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Comprehensive review on natural pharmacophore tethered 1,2, 3‐triazoles as active pharmaceuticals

https://doi.org/10.1111/cbdd.14148
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3‐Triazolylbenzyl‐aminophosphonates
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Synthesis of Isocryptolepine‐Triazole Adducts and Evaluation of Their Cytotoxic Activity
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1H‐Pyrazole‐Appended Pyridines and Their 1,2,4‐Triazine Precursors: A Rational Synthesis and in silico and in vitro Evaluation of Anti‐Cancer Activity
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Microwave‐Assisted Synthesis of N‐Substituted Maleimide Derivatives as Exogenous Antioxidant Agents
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Pharmakokinetic properties of noscapine
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Chalcone synthesis, properties and medicinal applications: a review
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Transition metal-based metal–organic frameworks for environmental applications: a review
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Green synthesis of xanthene and acridine-based heterocycles of pharmaceutical importance: a review
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Cyclodextrins as multitask agents for metal nano-heterogeneous catalysis: a review
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Heterocycles in drugs and drug discovery
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Lupane Triterpenoids—Betulin and Betulinic acid derivatives induce apoptosis in tumor cells
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Synthesis of 1,2,3-triazolyl nucleoside analogues and their antiviral activity
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Betulin and betulinic acid: triterpenoids derivatives with a powerful biological potential
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Medicinal attributes of 1,2,3-triazoles: Current developments
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New carbazole linked 1,2,3-triazoles as highly potent non-sugar α-glucosidase inhibitors
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Design, synthesis and biological evaluation of novel 1,2,3-triazole linked coumarinopyrazole conjugates as potent anticholinesterase, anti-5-lipoxygenase, anti-tyrosinase and anti-cancer agents
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Novel tacrine-coumarin hybrids linked to 1,2,3-triazole as anti-Alzheimer’s compounds: In vitro and in vivo biological evaluation and docking study
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Design, synthesis and anti-Alzheimer’s activity of novel 1,2,3-triazole-chromenone carboxamide derivatives
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Click chemistry based multicomponent approach in the synthesis of spirochromenocarbazole tethered 1,2,3-triazoles as potential anticancer agents
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Click chemistry-assisted synthesis of novel aminonaphthoquinone-1,2,3-triazole hybrids and investigation of their cytotoxicity and cancer cell cycle alterations
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Synthesis and biological evaluation of bergenin-1,2,3-triazole hybrids as novel class of anti-mitotic agents
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Biscoumarin-1,2,3-triazole hybrids as novel anti-diabetic agents: Design, synthesis, in vitro α-glucosidase inhibition, kinetic, and docking studies
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Molecular mechanism of action of new 1,4-naphthoquinones tethered to 1,2,3-1H-triazoles with cytotoxic and selective effect against oral squamous cell carcinoma
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Synthesis and antiplasmodial evaluation of 1H-1,2,3-triazole grafted 4-aminoquinoline-benzoxaborole hybrids and benzoxaborole analogues
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Isocryptolepine, an indoloquinoline alkaloid from Cryptolepis sanguinolenta promotes LDL uptake in HepG2 cells
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Cytotoxic and antitumoral properties in a series of new, ring D modified, olivacine analogues
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Novel 1,2,4-triazole and imidazole derivatives of l-ascorbic and imino-ascorbic acid: Synthesis, anti-HCV and antitumor activity evaluations
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(+)-Usnic acid enamines with remarkable cicatrizing properties
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1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview
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Chemo- and stereoselective synthesis of benzocycloheptene and 1-benzoxepin derivatives as α-sympathomimetic and anorexigenic agents
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Synthesis and antimicrobial activity of β-lactam–bile acid conjugates linked via triazole
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A new sesquiterpene lactone from the roots of Saussurea lappa: Structure–anticancer activity study
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5-Chloro-2-thiophenyl-1,2,3-triazolylmethyldihydroquinolines as dual inhibitors of Mycobacterium tuberculosis and influenza virus: Synthesis and evaluation
inferredcites →https://doi.org/10.1016/j.bmcl.2021.128092openalex-snapshot
Design and synthesis of novel diosgenin-triazole hybrids targeting inflammation as potential neuroprotective agents
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Discovery of 7-O-1, 2, 3-triazole hesperetin derivatives as multi-target-directed ligands against Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.ejmech.2014.02.050openalex-snapshot
Synthesis, antimicrobial and cytotoxic activities of pyrimidinyl benzoxazole, benzothiazole and benzimidazole
inferredcites →https://doi.org/10.1016/j.ejmech.2015.02.059openalex-snapshot
Biological potential of carbazole derivatives
inferredcites →https://doi.org/10.1016/j.ejmech.2015.11.018openalex-snapshot
A novel triazole derivative of betulinic acid induces extrinsic and intrinsic apoptosis in human leukemia HL-60 cells
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Design, synthesis and biological evaluation of novel l-ascorbic acid-conjugated pentacyclic triterpene derivatives as potential influenza virus entry inhibitors
inferredcites →https://doi.org/10.1016/j.ejmech.2017.12.051openalex-snapshot
Antimalarial naphthoquinones. Synthesis via click chemistry, in vitro activity, docking to PfDHODH and SAR of lapachol-based compounds
inferredcites →https://doi.org/10.1016/j.ejmech.2019.111739openalex-snapshot
Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives
inferredcites →https://doi.org/10.1016/j.ejmech.2019.112009openalex-snapshot
Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin
inferredcites →https://doi.org/10.1016/j.ejmech.2021.113162openalex-snapshot
Design and synthesis of 7-O-1,2,3-triazole hesperetin derivatives to relieve inflammation of acute liver injury in mice
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Diversity, pharmacology and synthesis of bergenin and its derivatives: Potential materials for therapeutic usages
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Novel substituted quinoxaline 1,4-dioxides with in vitro antimycobacterial and anticandida activity
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Synthesis and cytotoxicity of dihydroartemisinin ethers containing cyanoarylmethyl group
inferredcites →https://doi.org/10.1021/acs.jnatprod.6b00109openalex-snapshot
Usnic Acid Derivatives with Cytotoxic and Antifungal Activities from the Lichen Usnea longissima
inferredcites →https://doi.org/10.1021/acs.jnatprod.9b00475openalex-snapshot
Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents
inferredcites →https://doi.org/10.1021/acs.jproteome.0c00392openalex-snapshot
Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase, a Key Drug Target for COVID-19
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Synthesis and Immunosuppressive Activity of New Artemisinin Derivatives. 1. [12(β or α)-Dihydroartemisininoxy]phen(ox)yl Aliphatic Acids and Esters
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Benzoxepin-Derived Estrogen Receptor Modulators: A Novel Molecular Scaffold for the Estrogen Receptor
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Structure−Activity Modifications of the HIV-1 Inhibitors (+)-Calanolide A and (−)-Calanolide B
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SVCT-2 in breast cancer acts as an indicator for L-ascorbate treatment
inferredcites →https://doi.org/10.1039/c5md00224aopenalex-snapshot
Novel benzoxepine-1,2,3-triazole hybrids: synthesis and pharmacological evaluation as potential antibacterial and anticancer agents
inferredcites →https://doi.org/10.1039/c5ra16361gopenalex-snapshot
4-Aminoquinoline-hybridization en route towards the development of rationally designed antimalarial agents
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Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention
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“Click” reaction mediated synthesis of costunolide and dehydrocostuslactone derivatives and evaluation of their cytotoxic activity
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Synthesis and Bioactivity of Novel Trisubstituted Triazole Nucleosides
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Synthesis and anti-H5N1 virus activity of triazole- and oxadiazole-pyrimidine hybrids and their nucleoside analogs
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Triazole: A Promising Antitubercular Agent
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Coumarin: A Privileged Scaffold for the Design and Development of Antineurodegenerative Agents
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Naphthoquinones: A continuing source for discovery of therapeutic antineoplastic agents
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Vitamin C
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Synthesis of Novel Indolyl-1,2,4-triazoles as Potent and Selective Anticancer Agents
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Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology
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Derivatives of usnic acid inhibit broad range of influenza viruses and protect mice from lethal influenza infection
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Recent progress in the development of anti-malarial quinolones
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Recent development on naphthoquinone derivatives and their therapeutic applications as anticancer agents
inferredcites →https://doi.org/10.2174/0929867043365233openalex-snapshot
Recent Advances in Artemisinin and Its Derivatives as Antimalarial and Antitumor Agents
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An Overview of the Pharmacological Properties and Potential Applications of Natural Monoterpenes
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Semi-Synthesis of New 1,2,3-Triazole Derivatives of 9-Bromonoscapine and their Anticancer Activities.
inferredcites →https://doi.org/10.3109/14756360903524304openalex-snapshot
Pharmacological significance of triazole scaffold
inferredcites →https://doi.org/10.3389/fbioe.2021.662432openalex-snapshot
The Synthesis and Antitumor Activity of 1,8-Naphthalimide Derivatives Linked 1,2,3-Triazole
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Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation
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Monoterpenes and Their Derivatives—Recent Development in Biological and Medical Applications
inferredcites →https://doi.org/10.3390/molecules22020303openalex-snapshot
Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity
inferredcites →https://doi.org/10.3390/molecules22111876openalex-snapshot
Novel Triazole Hybrids of Betulin: Synthesis and Biological Activity Profile
inferredcites →https://doi.org/10.3390/molecules26113249openalex-snapshot
Synthesis and Antitumor Activity of 1-Substituted 1,2,3-Triazole-Mollugin Derivatives
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Design and Synthesis of (2-oxo-1,2-Dihydroquinolin-4-yl)-1,2,3-triazole Derivatives via Click Reaction: Potential Apoptotic Antiproliferative Agents
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Synthesis, Antifungal Activity, 3D-QSAR, and Molecular Docking Study of Novel Menthol-Derived 1,2,4-Triazole-thioether Compounds
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Synthesis and Biological Evaluation of 1,2,3-Triazole Tethered Thymol-1,3,4-Oxadiazole Derivatives as Anticancer and Antimicrobial Agents
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The Significance of 1, 2, 4 Triazoles in Agriculture Science: A Review

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Visible-Light-Induced Photocatalytic Iododi(Per)Fluoroalkylationof 5-Amino-N-Allyl-1,2,3-Triazole-4-Carboxamides
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Silver and Copper‐Catalyzed Cycloaddition Reactions of Isocyanide Esters
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Exploring the SAR of 1,2,3‐Triazoles as Tumor‐Associated Carbonic Anhydrases IX and XII Inhibitors for Anticancer Applications
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Design and Synthesis of Triazole‐Based p ‐ tert ‐Butylcalix[4]Arene Conjugates and Evaluation of Their Antimicrobial, Antibiofilm, and Anti‐Quorum‐Sensing Activities
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A New Insight Into The Huisgen Reaction: Heterogeneous Copper Catalyzed Azide‐Alkyne Cycloaddition for the Synthesis of 1,4‐Disubstituted Triazole (From 2018–2023)
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Assessment on Prominent Synthetic Approaches for the Cholesterol Absorption Inhibitor Ezetimibe and Their Process Impurities: A Review
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Bio‐Polymer Supported Heterogeneous Copper Catalysts for Azide‐Alkyne Cycloaddition Reactions: An Overview
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Triazole-functionalized compounds as promising antifungal agents: Synthesis, biological evaluation, and mechanistic insights
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The Benzoxazole Heterocycle: A Comprehensive Review of the Most Recent Medicinal Chemistry Developments of Antiproliferative, Brain-Penetrant, and Anti-inflammatory Agents
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Novel Functionalized Triazole/Carbazole-Based Chitosan: In Vitro, In Vivo and In Silico Evaluation of Anti-diabetic and Anti-obesity Activities
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Click Chemistry: An Outstanding Approach for Tuning Natural Products Bioactivities
inferred← citeshttps://doi.org/10.1016/b978-0-443-15742-4.00105-8openalex-snapshot
Microwave-Assisted Synthesis of Fine Chemicals – Triazoles
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Polymeric micelles loaded with a 1,2,3-triazolium derivative: a promising strategy against tegumentary leishmaniasis
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Design, synthesis and biological evaluation of a novel series of conjugates of N1-(phosphonoalkyl)-1,2,3-triazoles and N3-benzyl-6-bromoquinazoline-2,4-diones with anti-RSV activity
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Novel Piperlongumine derivatives exert multimodal antitumor effects in prostate cancer via MAPK pathway activation, poly-mechanistic apoptosis induction, and DNMT3A-mediated DNA methylation reduction
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Aurone synthesis and fluorescence properties for chemosensory, optoelectronic and biological applications: A review
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Triazole hybrid compounds: A new frontier in malaria treatment
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Unveiling the potential of click synthesized 1,2,3-triazole as an anticancer agent via in vivo, molecular docking and MD simulation approaches and its aptitude as plant growth regulator on Cajanus cajan
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Visible-light-induced photocatalytic iododi(per)fluoroalkylation of 5-amino-N-allyl-1,2,3-triazole-4-carboxamides
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inferred← citeshttps://doi.org/10.2174/0113852728268779240102101311openalex-snapshot
Nano-Biocomposites: A Versatile Combination of Nanocomposites and Biopolymers for the Synthesis of Heterocycles via Multicomponent Reactions
inferred← citeshttps://doi.org/10.3389/fchem.2023.1247805openalex-snapshot
1,2,3-Triazoles and their metal chelates with antimicrobial activity
inferred← citeshttps://doi.org/10.3390/catal13050835openalex-snapshot
Stereoselective Approach to Hydroxyalkyl-1,2,3-triazoles Containing Cyclooctane Core and Their Use for CuAAC Catalysis
inferred← citeshttps://doi.org/10.3390/ijms241713300openalex-snapshot
Synthesis, Antioxidant and Antiproliferative Actions of 4-(1,2,3-Triazol-1-yl)quinolin-2(1H)-ones as Multi-Target Inhibitors
inferred← citeshttps://doi.org/10.3390/molecules28155715openalex-snapshot
A Novel Betulinic Acid Analogue: Synthesis, Solubility, Antitumor Activity and Pharmacokinetic Study in Rats
inferred← citeshttps://doi.org/10.3390/reactions7030049openalex-snapshot
Regioselective Synthesis of 1,4-Disubstituted-1,2,3-triazole Hybrids Containing Isatin and 1,4-Dihydropyridines Mediated by Ionic Liquid/Water/Cu(I) System
inferred← citeshttps://doi.org/10.3762/bjoc.19.147openalex-snapshot
1-Butyl-3-methylimidazolium tetrafluoroborate as suitable solvent for BF 3 : the case of alkyne hydration. Chemistry vs electrochemistry
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