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Role of the CCL2‐CCR2 signalling axis in cancer: Mechanisms and therapeutic targeting
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Induction of inflammatory angiogenesis by monocyte chemoattractant protein-1
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EMT and inflammation: inseparable actors of cancer progression
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Klotho‐mediated targeting of CCL 2 suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments
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Metalloproteinases and their roles in human cancer
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CCL 2 as a potential therapeutic target for clear cell renal cell carcinoma
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Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2‐induced STAT3 activation
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PD‐1/PD‐L1 immune checkpoint: Potential target for cancer therapy
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Contribution of regulatory T cells to cancer: A review
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Perioperative cytokine levels portend early death after pancreatectomy for ductal adenocarcinoma
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Therapeutic strategies involving survivin inhibition in cancer
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Structural basis of chemokine and receptor interactions: Key regulators of leukocyte recruitment in inflammatory responses
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Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion
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Bindarit Attenuates Pain and Cancer-Related Inflammation by Influencing Myeloid Cells in a Model of Bone Cancer
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A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors
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The multifaceted roles of chemokines in malignancy
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CCL2 (Monocyte Chemoattractant Protein-1) in cancer bone metastases
inferredcites →https://doi.org/10.1007/s10585-008-9226-7openalex-snapshot
Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone
inferredcites →https://doi.org/10.1007/s10585-012-9473-5openalex-snapshot
Targeting monocyte chemotactic protein-1 synthesis with bindarit induces tumor regression in prostate and breast cancer animal models
inferredcites →https://doi.org/10.1007/s10585-019-09993-yopenalex-snapshot
CCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway
inferredcites →https://doi.org/10.1007/s10637-012-9869-8openalex-snapshot
Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer
inferredcites →https://doi.org/10.1007/s10637-019-00830-3openalex-snapshot
Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma
inferredcites →https://doi.org/10.1007/s11060-010-0473-5openalex-snapshot
Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy
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Carlumab, an anti-C-C chemokine ligand 2 monoclonal antibody, in combination with four chemotherapy regimens for the treatment of patients with solid tumors: an open-label, multicenter phase 1b study
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The Multifaceted Roles Neutrophils Play in the Tumor Microenvironment
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Purification of recombinant human chemokine CCL2 in E. coli and its function in ovarian cancer
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The CCL2/CCR2 axis enhances IL-6-induced epithelial-mesenchymal transition by cooperatively activating STAT3-Twist signaling
inferredcites →https://doi.org/10.1016/bs.acr.2019.12.002openalex-snapshot
Atypical chemokine receptors in tumor cell growth and metastasis
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Cancer metastases: challenges and opportunities
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CCL2 increases MMP-9 expression and cell motility in human chondrosarcoma cells via the Ras/Raf/MEK/ERK/NF-κB signaling pathway
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Small molecule inhibitors of the CCR2b receptor. Part 1: Discovery and optimization of homopiperazine derivatives
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MCP-1: Chemoattractant with a role beyond immunity: A review
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Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway
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Hallmarks of Cancer: The Next Generation
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CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function
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Tumor-associated macrophages
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Lymphocytes in cancer development: Polarization towards pro-tumor immunity
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A Natural CCR2 Antagonist Relieves Tumor-associated Macrophage-mediated Immunosuppression to Produce a Therapeutic Effect for Liver Cancer
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Serum CCL2 and serum TNF-α – Two new biomarkers predict bone invasion, post-treatment distant metastasis and poor overall survival in nasopharyngeal carcinoma
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CCL2 conditionally determines CCL22-dependent Th2-accumulation during TGF-β-induced breast cancer progression
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Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
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Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
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The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
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The CCR2+ Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers
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Targeted delivery of CCR2 antagonist to activated pulmonary endothelium prevents metastasis
inferredcites →https://doi.org/10.1016/j.jneuroim.2010.05.010openalex-snapshot
The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases
inferredcites →https://doi.org/10.1016/j.joms.2016.09.052openalex-snapshot
The CCL2-CCR2 Axis in Lymph Node Metastasis From Oral Squamous Cell Carcinoma: An Immunohistochemical Study
inferredcites →https://doi.org/10.1016/j.lfs.2020.118808openalex-snapshot
Loganin alleviates macrophage infiltration and activation by inhibiting the MCP-1/CCR2 axis in diabetic nephropathy
inferredcites →https://doi.org/10.1016/j.lfs.2021.119034openalex-snapshot
Role of CCL2/CCR2 axis in the immunopathogenesis of rheumatoid arthritis: Latest evidence and therapeutic approaches
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The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
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Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888
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RS 504393 inhibits M-MDSCs recruiting in immune microenvironment of bladder cancer after gemcitabine treatment
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Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers
inferredcites →https://doi.org/10.1016/j.prp.2016.12.013openalex-snapshot
CCL2 expression correlates with Snail expression and affects the prognosis of patients with gastric cancer
inferredcites →https://doi.org/10.1016/j.str.2018.10.027openalex-snapshot
Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists
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High expression of chemokine CCL2 is associated with recurrence after surgery in clear-cell renal cell carcinoma
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Chemokines in tumor development and progression
inferredcites →https://doi.org/10.1016/s1359-6101(99)00005-2openalex-snapshot
The MCP/eotaxin subfamily of CC chemokines
inferredcites →https://doi.org/10.1016/s1470-2045(16)00078-4openalex-snapshot
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial
inferredcites →https://doi.org/10.1016/s1471-4906(02)02302-5openalex-snapshot
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
inferredcites →https://doi.org/10.1021/acs.jmedchem.6b01309openalex-snapshot
Structural Analysis of Chemokine Receptor–Ligand Interactions
inferredcites →https://doi.org/10.1038/35006097openalex-snapshot
Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1
inferredcites →https://doi.org/10.1038/84205openalex-snapshot
Chemokines as regulators of T cell differentiation
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MCP-1-induced ERK/GSK-3β/Snail signaling facilitates the epithelial–mesenchymal transition and promotes the migration of MCF-7 human breast carcinoma cells
inferredcites →https://doi.org/10.1038/cmi.2017.135openalex-snapshot
The chemokine MCP-1 (CCL2) in the host interaction with cancer: a foe or ally?
inferredcites →https://doi.org/10.1038/cmi.2018.9openalex-snapshot
Chemokines: the past, the present and the future
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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
inferredcites →https://doi.org/10.1038/nature10138openalex-snapshot
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
inferredcites →https://doi.org/10.1038/nature13862openalex-snapshot
Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis
inferredcites →https://doi.org/10.1038/ni.2812openalex-snapshot
New nomenclature for atypical chemokine receptors
inferredcites →https://doi.org/10.1038/nrc.2017.51openalex-snapshot
Microenvironmental regulation of tumour angiogenesis
inferredcites →https://doi.org/10.1038/nrc.2017.6openalex-snapshot
Pre-metastatic niches: organ-specific homes for metastases
inferredcites →https://doi.org/10.1038/nri2506openalex-snapshot
Myeloid-derived suppressor cells as regulators of the immune system
inferredcites →https://doi.org/10.1038/nri3902openalex-snapshot
Immunological hallmarks of stromal cells in the tumour microenvironment
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Development of a genetically encodable FRET system using fluorescent RNA aptamers
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LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment
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A history of exploring cancer in context
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A framework for advancing our understanding of cancer-associated fibroblasts
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Turning foes to friends: targeting cancer-associated fibroblasts
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Sex-specific adipose tissue imprinting of regulatory T cells
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Correlative Factors of the Deterioration of Necrotizing Enterocolitis in Small for Gestational Age Newborns
inferredcites →https://doi.org/10.1038/s41598-018-27810-6openalex-snapshot
Estrogen promotes progression of hormone-dependent breast cancer through CCL2-CCR2 axis by upregulation of Twist via PI3K/AKT/NF-κB signaling
inferredcites →https://doi.org/10.1038/s41598-019-47438-4openalex-snapshot
Increased Antiangiogenic Effect by Blocking CCL2-dependent Macrophages in a Rodent Glioblastoma Model: Correlation Study with Dynamic Susceptibility Contrast Perfusion MRI
inferredcites →https://doi.org/10.1038/s41598-020-62416-xopenalex-snapshot
Metastasis-associated fibroblasts promote angiogenesis in metastasized pancreatic cancer via the CXCL8 and the CCL2 axes
inferredcites →https://doi.org/10.1038/s42003-020-01441-yopenalex-snapshot
Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy
inferredcites →https://doi.org/10.1038/sj.jid.5700827openalex-snapshot
Targeting Tumor-Associated Macrophages and Inhibition of MCP-1 Reduce Angiogenesis and Tumor Growth in a Human Melanoma Xenograft
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Monocyte subtypes and the CCR2 chemokine receptor in cardiovascular disease
inferredcites →https://doi.org/10.1056/nejmoa1011923openalex-snapshot
FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
inferredcites →https://doi.org/10.1067/mai.2003.1594openalex-snapshot
Chemokines: Roles in leukocyte development, trafficking, and effector function
inferredcites →https://doi.org/10.1073/pnas.1910856117openalex-snapshot
CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas
inferredcites →https://doi.org/10.1073/pnas.91.7.2752openalex-snapshot
Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.
inferredcites →https://doi.org/10.1074/jbc.272.2.1038openalex-snapshot
Organization and Differential Expression of the Human Monocyte Chemoattractant Protein 1 Receptor Gene
inferredcites →https://doi.org/10.1074/jbc.m000692200openalex-snapshot
Identification of the Binding Site for a Novel Class of CCR2b Chemokine Receptor Antagonists
inferredcites →https://doi.org/10.1074/jbc.m112.365999openalex-snapshot
CCL2/CCR2 Chemokine Signaling Coordinates Survival and Motility of Breast Cancer Cells through Smad3 Protein- and p42/44 Mitogen-activated Protein Kinase (MAPK)-dependent Mechanisms
inferredcites →https://doi.org/10.1074/jbc.m801073200openalex-snapshot
CCL2 Protects Prostate Cancer PC3 Cells from Autophagic Death via Phosphatidylinositol 3-Kinase/AKT-dependent Survivin Up-regulation
inferredcites →https://doi.org/10.1080/2162402x.2018.1470729openalex-snapshot
Recruitment of CCR2+tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer
inferredcites →https://doi.org/10.1084/jem.169.4.1449openalex-snapshot
Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants.
inferredcites →https://doi.org/10.1084/jem.169.4.1485openalex-snapshot
Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line.
inferredcites →https://doi.org/10.1084/jem.20141836openalex-snapshot
CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages
inferredcites →https://doi.org/10.1084/jem.20181551openalex-snapshot
Cancer cell CCR2 orchestrates suppression of the adaptive immune response
inferredcites →https://doi.org/10.1089/107999002760624305openalex-snapshot
Chemokine/Chemokine Receptor Nomenclature
inferredcites →https://doi.org/10.1089/jir.2008.0027openalex-snapshot
Monocyte Chemoattractant Protein-1 (MCP-1): An Overview
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Curcumin's Effect on Intestinal Inflammation and Tumorigenesis in the Apc Min/+ Mouse
inferredcites →https://doi.org/10.1089/jir.2018.0113openalex-snapshot
MCP-1/CCL2 Mediated by Autocrine Loop of PDGF-BB Promotes Invasion of Lung Cancer Cell by Recruitment of Macrophages Via CCL2–CCR2 Axis
inferredcites →https://doi.org/10.1089/thy.2008.0237openalex-snapshot
The Expression of Monocyte Chemotactic Protein-1 in Papillary Thyroid Carcinoma Is Correlated with Lymph Node Metastasis and Tumor Recurrence
inferredcites →https://doi.org/10.1093/carcin/bgu046openalex-snapshot
A CCL2/ROS autoregulation loop is critical for cancer-associated fibroblasts-enhanced tumor growth of oral squamous cell carcinoma
inferredcites →https://doi.org/10.1093/jnci/djn325openalex-snapshot
A Central Role for Tumor-derived Monocyte Chemoattractant Protein-1 in Malignant Pleural Effusion
inferredcites →https://doi.org/10.1093/jnci/djq044openalex-snapshot
Multiple Roles of Chemokine (C-C Motif) Ligand 2 in Promoting Prostate Cancer Growth
inferredcites →https://doi.org/10.1097/moh.0000000000000389openalex-snapshot
The regulation and importance of monocyte chemoattractant protein-1
inferredcites →https://doi.org/10.1097/pap.0000000000000219openalex-snapshot
Paget’s “Seed and Soil” Theory of Cancer Metastasis: An Idea Whose Time has Come
inferredcites →https://doi.org/10.1101/cshperspect.a016303openalex-snapshot
The Chemokine System in Innate Immunity
inferredcites →https://doi.org/10.1111/1759-7714.12643openalex-snapshot
High levels of CCL2 or CCL4 in the tumor microenvironment predict unfavorable survival in lung adenocarcinoma
inferredcites →https://doi.org/10.1111/cas.14075openalex-snapshot
Potentials of C‐C motif chemokine 2–C‐C chemokine receptor type 2 blockers including propagermanium as anticancer agents
inferredcites →https://doi.org/10.1111/cas.14230openalex-snapshot
Tumor‐associated macrophages secrete CC‐chemokine ligand 2 and induce tamoxifen resistance by activating PI3K/Akt/mTOR in breast cancer
inferredcites →https://doi.org/10.1111/cas.14306openalex-snapshot
Phase I dose‐escalation trial to repurpose propagermanium, an oral CCL2 inhibitor, in patients with breast cancer
inferredcites →https://doi.org/10.1111/febs.14466openalex-snapshot
A guide to chemokines and their receptors
inferredcites →https://doi.org/10.1111/imm.12910openalex-snapshot
Implications of macrophage polarization in autoimmunity
inferredcites →https://doi.org/10.1124/pr.111.005074openalex-snapshot
CC Chemokine Receptors and Chronic Inflammation—Therapeutic Opportunities and Pharmacological Challenges
inferredcites →https://doi.org/10.1126/science.1203543openalex-snapshot
A Perspective on Cancer Cell Metastasis
inferredcites →https://doi.org/10.1126/science.aax0182openalex-snapshot
Neoadjuvant checkpoint blockade for cancer immunotherapy
inferredcites →https://doi.org/10.1126/scisignal.aai8529openalex-snapshot
Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2
inferredcites →https://doi.org/10.1136/gutjnl-2015-310514openalex-snapshot
Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma
inferredcites →https://doi.org/10.1136/gutjnl-2017-313738openalex-snapshot
Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma
inferredcites →https://doi.org/10.1136/jitc-2020-001341openalex-snapshot
Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer
inferredcites →https://doi.org/10.1152/physrev.00012.2018openalex-snapshot
The Neutrophil’s Role During Health and Disease
inferredcites →https://doi.org/10.1155/2018/2124390openalex-snapshot
Plasma Chemokine CCL2 and Its Receptor CCR2 Concentrations as Diagnostic Biomarkers for Breast Cancer Patients
inferredcites →https://doi.org/10.1158/0008-5472.can-07-1286openalex-snapshot
Targeting CCL2 with Systemic Delivery of Neutralizing Antibodies Induces Prostate Cancer Tumor Regression In vivo
inferredcites →https://doi.org/10.1158/0008-5472.can-09-2326openalex-snapshot
CCL2 Blockade Augments Cancer Immunotherapy
inferredcites →https://doi.org/10.1158/0008-5472.can-10-0299openalex-snapshot
Correction: CCL2 Blockade Augments Cancer Immunotherapy
inferredcites →https://doi.org/10.1158/0008-5472.can-11-3873openalex-snapshot
Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
inferredcites →https://doi.org/10.1158/0008-5472.can-15-2973openalex-snapshot
FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3–CCL2 Signaling
inferredcites →https://doi.org/10.1158/0008-5472.can-16-0144openalex-snapshot
CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-16-0984openalex-snapshot
CCR2 Influences T Regulatory Cell Migration to Tumors and Serves as a Biomarker of Cyclophosphamide Sensitivity
inferredcites →https://doi.org/10.1158/1078-0432.ccr-13-0525openalex-snapshot
Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis
inferredcites →https://doi.org/10.1158/1078-0432.ccr-16-0870openalex-snapshot
Tumor-Derived CCL2 Mediates Resistance to Radiotherapy in Pancreatic Ductal Adenocarcinoma
inferredcites →https://doi.org/10.1158/1535-7163.mct-16-0124openalex-snapshot
Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
inferredcites →https://doi.org/10.1158/2326-6066.cir-18-0633openalex-snapshot
CCR2-Dependent Recruitment of Tregs and Monocytes Following Radiotherapy Is Associated with TNFα-Mediated Resistance
inferredcites →https://doi.org/10.1158/2326-6066.cir-18-0763openalex-snapshot
Tumor-Specific Regulatory T Cells from the Bone Marrow Orchestrate Antitumor Immunity in Breast Cancer
inferredcites →https://doi.org/10.1159/000495276openalex-snapshot
The Spleen Promotes the Secretion of CCL2 and Supports an M1 Dominant Phenotype in Hepatic Macrophages During Liver Fibrosis
inferredcites →https://doi.org/10.1161/01.atv.19.9.2085openalex-snapshot
Expression of CCR2 by Endothelial Cells
inferredcites →https://doi.org/10.1172/jci119798openalex-snapshot
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.
inferredcites →https://doi.org/10.1172/jci80006openalex-snapshot
Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages
inferredcites →https://doi.org/10.1182/blood.v96.1.34openalex-snapshot
Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression
inferredcites →https://doi.org/10.1183/13993003.01562-2018openalex-snapshot
Role of anlotinib-induced CCL2 decrease in anti-angiogenesis and response prediction for nonsmall cell lung cancer therapy
inferredcites →https://doi.org/10.1186/1476-4598-10-121openalex-snapshot
A MCP1 fusokine with CCR2-specific tumoricidal activity
inferredcites →https://doi.org/10.1186/bcr3143openalex-snapshot
New tricks for metastasis-associated macrophages
inferredcites →https://doi.org/10.1186/s12943-017-0742-4openalex-snapshot
Factors involved in cancer metastasis: a better understanding to “seed and soil” hypothesis
inferredcites →https://doi.org/10.1186/s12943-020-01165-xopenalex-snapshot
CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis
inferredcites →https://doi.org/10.1186/s13041-020-00701-6openalex-snapshot
CCL2 facilitates spinal synaptic transmission and pain via interaction with presynaptic CCR2 in spinal nociceptor terminals
inferredcites →https://doi.org/10.1186/s13045-019-0760-3openalex-snapshot
Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
inferredcites →https://doi.org/10.1186/s13046-020-01756-yopenalex-snapshot
Monocyte Chemoattractant Protein-1 promotes cancer cell migration via c-Raf/MAPK/AP-1 pathway and MMP-9 production in osteosarcoma
inferredcites →https://doi.org/10.1200/jco.2018.36.5_suppl.92openalex-snapshot
Overall survival in a trial of orally administered CCR2 inhibitor CCX872 in locally advanced/metastatic pancreatic cancer: Correlation with blood monocyte counts.
inferredcites →https://doi.org/10.1371/journal.pgen.1006244openalex-snapshot
Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling
inferredcites →https://doi.org/10.1371/journal.pone.0006562openalex-snapshot
A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth
inferredcites →https://doi.org/10.1371/journal.pone.0068904openalex-snapshot
Identification of Serum Monocyte Chemoattractant Protein-1 and Prolactin as Potential Tumor Markers in Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1371/journal.pone.0145342openalex-snapshot
Novel Markers to Delineate Murine M1 and M2 Macrophages
inferredcites →https://doi.org/10.1387/ijdb.041814hkopenalex-snapshot
The chemokine network in cancer - much more than directing cell movement
inferredcites →https://doi.org/10.1593/neo.07307openalex-snapshot
CCL2 as an Important Mediator of Prostate Cancer Growth In Vivo through the Regulation of Macrophage Infiltration
inferredcites →https://doi.org/10.18632/oncotarget.10492openalex-snapshot
CCL2/CCR2 axis is associated with postoperative survival and recurrence of patients with non-metastatic clear-cell renal cell carcinoma
inferredcites →https://doi.org/10.18632/oncotarget.16837openalex-snapshot
Targeting CCR2 with its antagonist suppresses viability, motility and invasion by downregulating MMP-9 expression in non-small cell lung cancer cells
inferredcites →https://doi.org/10.18632/oncotarget.6690openalex-snapshot
Serum chemokine (CC motif) ligand 2 level as a diagnostic, predictive, and prognostic biomarker for prostate cancer
inferredcites →https://doi.org/10.18632/oncotarget.6695openalex-snapshot
CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway
inferredcites →https://doi.org/10.18632/oncotarget.7376openalex-snapshot
Targeting the CCL2-CCR2 signaling axis in cancer metastasis
inferredcites →https://doi.org/10.18632/oncotarget.8069openalex-snapshot
High expression of C-C chemokine receptor 2 associates with poor overall survival in gastric cancer patients after surgical resection
inferredcites →https://doi.org/10.2147/cmar.s196355openalex-snapshot
ELF-1 expression in nasopharyngeal carcinoma facilitates proliferation and metastasis of cancer cells via modulation of CCL2/CCR2 signaling
inferredcites →https://doi.org/10.2210/pdb6gps/pdbopenalex-snapshot
CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812
inferredcites →https://doi.org/10.3389/fcell.2020.594372openalex-snapshot
Notch3 Knockout Suppresses Mouse Mammary Gland Development and Inhibits the Proliferation of 4T1 Murine Mammary Carcinoma Cells via CCL2/CCR4 Axis
inferredcites →https://doi.org/10.3389/fimmu.2019.00147openalex-snapshot
Support of Tumor Endothelial Cells by Chemokine Receptors
inferredcites →https://doi.org/10.3389/fonc.2019.00013openalex-snapshot
Survivin in Insulin-Like Growth Factor-Induced Resistance to Lapatinib in Head and Neck Squamous Carcinoma Cells
inferredcites →https://doi.org/10.3389/fonc.2019.00231openalex-snapshot
CCL2/CCR2 Axis Promotes the Progression of Salivary Adenoid Cystic Carcinoma via Recruiting and Reprogramming the Tumor-Associated Macrophages
inferredcites →https://doi.org/10.3389/fonc.2020.00014openalex-snapshot
A Risk Stratification Model for Predicting Overall Survival and Surgical Benefit in Triple-Negative Breast Cancer Patients With de novo Distant Metastasis
inferredcites →https://doi.org/10.3389/fonc.2020.00019openalex-snapshot
Schwann Cell-Derived CCL2 Promotes the Perineural Invasion of Cervical Cancer
inferredcites →https://doi.org/10.3390/biomedicines5020012openalex-snapshot
Novel Computerized Method for Measurement of Retinal Vessel Diameters
inferredcites →https://doi.org/10.3390/biomedicines5020034openalex-snapshot
The Role of Angiogenesis in Cancer Treatment
inferredcites →https://doi.org/10.3390/cancers12020287openalex-snapshot
Chemokines and their Receptors: Multifaceted Roles in Cancer Progression and Potential Value as Cancer Prognostic Markers
inferredcites →https://doi.org/10.3390/cancers12051253openalex-snapshot
CCL2 Expression in Tumor Cells and Tumor-Infiltrating Immune Cells Shows Divergent Prognostic Potential for Bladder Cancer Patients Depending on Lymph Node Stage
inferredcites →https://doi.org/10.3390/cells9030561openalex-snapshot
Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer
inferredcites →https://doi.org/10.3390/ijms21124449openalex-snapshot
Cytokines and Chemokines as Mediators of Prostate Cancer Metastasis
inferredcites →https://doi.org/10.3748/wjg.v20.i15.4421openalex-snapshot
Expression of monocyte chemotactic protein-1/CCL2 in gastric cancer and its relationship with tumor hypoxia
inferredcites →https://doi.org/10.3892/ijo_00000259openalex-snapshot
Curcumin blocks CCL2-induced adhesion, motility and invasion, in part, through down-regulation of CCL2 expression and proteolytic activity
inferredcites →https://doi.org/10.3892/ol.2018.8769openalex-snapshot
CCL2 influences the sensitivity of lung cancer A549 cells to docetaxel
inferredcites →https://doi.org/10.3892/or.2017.6069openalex-snapshot
CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in�vitro through activation of the Hedgehog pathway
inferredcites →https://doi.org/10.3892/or.2018.6660openalex-snapshot
C‑C chemokine receptor type�2 promotes epithelial‑to‑mesenchymal transition by upregulating matrix metalloproteinase‑2 in human liver cancer
inferredcites →https://doi.org/10.4049/jimmunol.142.6.1956openalex-snapshot
Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes.
inferredcites →https://doi.org/10.4049/jimmunol.159.4.1993openalex-snapshot
Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines
inferredcites →https://doi.org/10.4049/jimmunol.177.4.2651openalex-snapshot
CCL2 Regulates Angiogenesis via Activation of Ets-1 Transcription Factor
inferredcites →https://doi.org/10.4049/jimmunol.181.8.5791openalex-snapshot
Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice
inferredcites →https://doi.org/10.4172/2155-9899.1000308openalex-snapshot
Monocyte-Induced Prostate Cancer Cell Invasion is Mediated by Chemokine ligand 2 and Nuclear Factor-κB Activity
inferredcites →https://doi.org/10.7150/ijbs.25349openalex-snapshot
CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistance in gastric cancer
inferredcites →https://doi.org/10.7150/jca.17648openalex-snapshot
Role of tumor microenvironment in tumorigenesis
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Role of CAPN5 in Tumor Immune Microenvironment Based on Multi-Omics: From BLCA Molecular Subtypes to Therapeutic Prediction
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Cancer‐Associated Fibroblast‐Induced Remodeling of Tumor Microenvironment in Recurrent Bladder Cancer
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Hydrogen Therapy Reverses Cancer‐Associated Fibroblasts Phenotypes and Remodels Stromal Microenvironment to Stimulate Systematic Anti‐Tumor Immunity
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Ccl2‐Induced Regulatory T Cells Balance Inflammation Through Macrophage Polarization During Liver Reconstitution
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Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications
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CCN1 Enhances Tumor Immunosuppression through Collagen‐Mediated Chemokine Secretion in Pancreatic Cancer
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PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity
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Pure total flavonoids from citrus improve nonalcoholic steatohepatitis liver inflammatory responses by regulating the CCL2 / CCR2‐PI3K‐Akt signal transduction pathway
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Chemokines as possible therapeutic targets in metastatic melanoma
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Circulating CD3 + CD8 + T Lymphocytes as Indicators of Disease Status in Patients With Early Breast Cancer
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Increased plasma levels of monocyte chemoattractant protein‐1 in patients with hepatitis B virus pre‐S2 gene deletion mutation predict a higher risk of hepatocellular carcinoma recurrence after curative surgical resection
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Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non‐infectious uveitis
inferred← citeshttps://doi.org/10.1002/dc.70165openalex-snapshot
Diagnostic Value of CCL2 and CCR2 in Pleural Effusion for Distinguishing Lung Cancer Histological Subtypes: A Retrospective Study
inferred← citeshttps://doi.org/10.1002/jcp.31489openalex-snapshot
CCL2‐CCR2 Axis Inhibition in Osteosarcoma Cell Model: The Impact of Oxygen Level on Cell Phenotype
inferred← citeshttps://doi.org/10.1002/jgm.3708openalex-snapshot
Lysophosphatidic acid promotes ESCC progression by increasing the level of CCL2 secreted by esophageal epithelial cells
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A Novel Peptide, HS1002, Enhances Antitumor Activity via Dual Targeting of the GnRH Receptor and Human Telomerase Reverse Transcriptase in Prostate Cancer Cells
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Novel chemokine biomarkers in melanoma†
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Nanoengineered Macrophages Armed with TLR7/8 Agonist Enhance Remodeling of Immunosuppressive Tumor Microenvironment
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Role of formyl peptide receptor 2 in steatosis of L02 cells exposed to Mono‐(2‐ethylhexyl) phthalate
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Development of Monobody Variants for Functional Mirror-Image Protein Therapeutics
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Protein–Protein Interactions in Cancer
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Cytokines and Chemokines in Tumor Growth and Progression
inferred← citeshttps://doi.org/10.1007/978-981-99-4657-0_9openalex-snapshot
CCL2–CCR2 Signaling Axis in Cancer
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The role of macrophages in the tumor microenvironment and tumor metabolism
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CircHSPB6 Promotes Tumor-Associated Macrophages M2 Polarization and Infiltration to Accelerate Cell Malignant Properties in Lung Adenocarcinoma by CCL2
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Lipotoxicity, lipid peroxidation and ferroptosis: a dilemma in cancer therapy
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Antigen presenting cells in cancer immunity and mediation of immune checkpoint blockade
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FTO-Mediated m6A Demethylation of CCL2 Promotes Gastric Cancer Progression via Autophagy and Oxidative Stress Regulation
inferred← citeshttps://doi.org/10.1007/s11033-024-09315-wopenalex-snapshot
Osteosarcoma cells exhibit functional interactions with stromal cells, fostering a lung microenvironment conducive to the establishment of metastatic tumor cells
inferred← citeshttps://doi.org/10.1007/s11033-025-11231-6openalex-snapshot
Tumor microenvironment in breast cancer: cellular crosstalk, pathways, and therapeutic insights
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Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines
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Comparative transcriptomic and machine learning analysis identifies key genes and immune dysregulation in goats exposed to peste des petits ruminants virus
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Roles of Chemokines in Intervertebral Disk Degeneration
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Prenatal Programming of Monocyte Chemotactic Protein-1 Signaling in Autism Susceptibility
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Tumor Necrosis Factor Alpha-Mediated Interaction Between Microglia and Müller Cells Exacerbates Retinal Ganglion Cell Damage in Experimental Glaucoma
inferred← citeshttps://doi.org/10.1007/s12264-025-01519-9openalex-snapshot
Chemokine CCL2 Mediates Neuroglial Crosstalk and Drives Chronic Pain Pathogenesis
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Histological spatial analysis on the induction of PD-L1+ macrophages by CD8+ T cells at the marginal microenvironment of triple-negative breast cancer
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Causal association between immune cell phenotypes and colorectal cancer: a two-sample bidirectional Mendelian randomization analysis
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Long non-coding RNA TMEM51-AS1 inhibits colorectal cancer progression
inferred← citeshttps://doi.org/10.1007/s12672-025-03258-9openalex-snapshot
Advances in the regulation of macrophage polarization by the tumor microenvironment
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ADAMDEC1-driven CCL2-CCR2-PD-1 axis in esophageal squamous cell carcinoma: a dual threat of O-GlcNAcylation and m6A methylation in neoadjuvant therapy resistance and immune evasion
inferred← citeshttps://doi.org/10.1007/s40259-026-00777-xopenalex-snapshot
Progress in Designing Cytokine Antagonist Antibodies for Cancer Therapy
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The CCL2/CCR2 axis in irradiated tumors: orchestrating immune recruitment and microenvironment remodeling
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Therapeutic potentials of medicinal plants and significance of computational tools in anti-cancer drug discovery
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Targeting short-lived immunosuppressive myeloid cells for PDAC therapy
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Elucidating mechanisms of endocrine resistance in estrogen receptor-positive breast cancer
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Chemotactic signaling pathways in prostate cancer: Implications in the tumor microenvironment and as potential therapeutic targets
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Chemokine receptors in COVID-19 infection
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CCR2-overexpressing biomimetic carrier-free nanoplatform for enhanced cascade ferroptosis tumor therapy
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Inhibition of the Rho/ROCK pathway promotes the expression of developmental and migration-related genes in astrocytes exposed to alcohol
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Targeting cytokine/chemokine signaling to convert immunologically cold tumors into hot: Emerging strategies in cancer immunotherapy
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The phoQ gene of Pseudomonas plecoglossicida influences the immune response in Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂ during infection
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Significance of the Monocyte CCR2-CCL2 Axis in Triple-negative Breast Cancer
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NLRP6 deficiency suppresses colorectal cancer liver metastasis growth by modulating M-MDSC-induced immunosuppressive microenvironment
inferred← citeshttps://doi.org/10.1016/j.bbcan.2023.188891openalex-snapshot
S100A8 and S100A9 in Cancer
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Colorectal cancer chemoprevention: Exploring the path from molecular mechanisms to available drugs
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Innate immune cells in oral squamous cell carcinoma: Characteristics and therapeutic potential
inferred← citeshttps://doi.org/10.1016/j.bbcan.2026.189702openalex-snapshot
Metabolic and epigenetic plasticity of tumor-associated macrophages shapes immunosuppressive outputs and immune checkpoint response
inferred← citeshttps://doi.org/10.1016/j.bbi.2026.106471openalex-snapshot
Depression-related chronic stress promotes ovarian cancer progression via metabolic dysfunction and IRF1-mediated immune suppression
inferred← citeshttps://doi.org/10.1016/j.bbrc.2024.150437openalex-snapshot
Mechanisms by which obesity regulates inflammation and anti-tumor immunity in cancer
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Supernatants from DNase-deficient Prevotella intermedia strains enhance oral squamous cell carcinoma cell migration and invasion by activating inflammatory and epithelial–mesenchymal transition pathways
inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115399openalex-snapshot
Impact of cancer-associated mutations in CC chemokine receptor 2 on receptor function and antagonism
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116258openalex-snapshot
Hiding in plain sight: Do recruited dendritic cells surround amyloid plaques in Alzheimer’s disease?
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116464openalex-snapshot
CC chemokine receptor 2 is allosterically modulated by sodium ions and amiloride derivatives through a distinct sodium ion binding site
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Enhanced antitumor immune response in melanoma-bearing mice via attenuated Salmonella carrying an IL-21-shRNA-CCR2 co-expression plasmid
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An injectable and antifouling hydrogel prevents the development of abdominal adhesions by inhibiting the CCL2/CCR2 interaction
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Self-regulating immunosuppressive tumor microenvironment by NIR-II photothermal agent with anti-inflammatory activity for self-reinforcing immunotherapy synergy with cancer photothermal ablation
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.109422openalex-snapshot
Macelignan targets SLC7A11 to induce ferroptosis and modulate macrophage polarization via STAT6/PPAR-γ/KLF4 signaling
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115792openalex-snapshot
Ulipristal acetate, a selective progesterone receptor modulator, induces cell death via inhibition of STAT3/CCL2 signaling pathway in uterine sarcoma
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115974openalex-snapshot
Canagliflozin reduces thyroid cancer cells migration in vitro by inhibiting CXCL8 and CCL2: An additional anti-tumor effect of the drug
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116775openalex-snapshot
Oligopeptide-strategy of targeting at adipose tissue macrophages using ATS-9R/siCcl2 complex for ameliorating insulin resistance in GDM
inferred← citeshttps://doi.org/10.1016/j.bneo.2025.100095openalex-snapshot
Tumor-associated myeloid cells support murine T-ALL in the central nervous system via integrin signaling
inferred← citeshttps://doi.org/10.1016/j.bone.2026.117898openalex-snapshot
Anabolic effect of parathyroid hormone (1–34) to prevent ovariectomy induced bone loss is attenuated in Col1A1-cre floxed monocyte chemotactic protein 1 (MCP1, CCL2) mice
inferred← citeshttps://doi.org/10.1016/j.canlet.2024.217106openalex-snapshot
Drug-induced senescence by aurora kinase inhibitors attenuates innate immune response of macrophages on gastric cancer organoids
inferred← citeshttps://doi.org/10.1016/j.canlet.2025.217692openalex-snapshot
TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.canlet.2025.218068openalex-snapshot
MRC2 expression modulates metabolism in acute myeloid leukemia stem cells
inferred← citeshttps://doi.org/10.1016/j.canlet.2025.218175openalex-snapshot
BMP9 potentiates immunotherapy in triple-negative breast cancer by suppressing Tregs infiltration via the PRKDC-CCL2 axis
inferred← citeshttps://doi.org/10.1016/j.canlet.2026.218437openalex-snapshot
The hallmarks of pancreatic cancer
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Ferritin nanocages facilitate PROTAC delivery for enhanced targeted therapy in triple-negative breast cancer
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The CCL2 network in pulmonary hypertension: Potential therapeutic targets
inferred← citeshttps://doi.org/10.1016/j.compbiolchem.2025.108746openalex-snapshot
DiffuScope: A diffusion-regularized autoencoder for spatial transcriptomic clustering
inferred← citeshttps://doi.org/10.1016/j.compbiomed.2024.109415openalex-snapshot
Transcriptome analysis displays new molecular insights into the mechanisms of action of Mebendazole in gastric cancer cells
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GOReverseLookup: A gene ontology reverse lookup tool
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Progression of radio-labeled molecular imaging probes targeting chemokine receptors
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2024.104362openalex-snapshot
Potential therapeutic targets in myeloid cell therapy for overcoming chemoresistance and immune suppression in gastrointestinal tumors
inferred← citeshttps://doi.org/10.1016/j.cyto.2026.157170openalex-snapshot
Can CCR2+ non-classical monocytes serve as a diagnostic biomarker in HER2-negative breast cancer? A pilot study
inferred← citeshttps://doi.org/10.1016/j.ejphar.2023.176304openalex-snapshot
Roles of PPAR activation in cancer therapeutic resistance: Implications for combination therapy and drug development
inferred← citeshttps://doi.org/10.1016/j.ejphar.2024.176357openalex-snapshot
Advance in the role of chemokines/chemokine receptors in carcinogenesis: Focus on pancreatic cancer
inferred← citeshttps://doi.org/10.1016/j.ejphar.2024.177157openalex-snapshot
Cinobufagin modulates vasculogenic mimicry and tumor-associated macrophages to inhibit ovarian cancer progression
inferred← citeshttps://doi.org/10.1016/j.gendis.2024.101323openalex-snapshot
The scRNA-sequencing landscape of pancreatic ductal adenocarcinoma revealed distinct cell populations associated with tumor initiation and progression
inferred← citeshttps://doi.org/10.1016/j.gendis.2026.102115openalex-snapshot
Single-cell RNA sequencing reveals FOLR2+ macrophages interaction with HSPA6+ NSCLC cells via CCL2/ICAM-1 in malignant pleural effusion and promotes EGFR-TKI resistance
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e39419openalex-snapshot
Analyzing the impact of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) on the reproductive system using network toxicology and molecular docking
inferred← citeshttps://doi.org/10.1016/j.humimm.2024.110805openalex-snapshot
Unravelling drivers of cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa
inferred← citeshttps://doi.org/10.1016/j.intimp.2022.109569openalex-snapshot
Tumor-associated macrophages employ immunoediting mechanisms in colorectal tumor progression: Current research in Macrophage repolarization immunotherapy
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110570openalex-snapshot
CCR2 antagonist represses fibroblast-like synoviocyte-mediated inflammation in patients with rheumatoid arthritis
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111877openalex-snapshot
Gut microbiome-mediated monocytes promote liver metastasis
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112328openalex-snapshot
Decoding the role of the CCL2/CCR2 axis in Alzheimer’s disease and innovating therapeutic approaches: Keeping All options open
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113865openalex-snapshot
Recent advances targeting chemokines for breast cancer
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114721openalex-snapshot
Puerarin exerts an inhibitory effect on inflammatory infiltration in the cardiac tissue of EAM mice by regulation of the TNF-α/CCL2/CCR2 signal pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2026.117338openalex-snapshot
Targeting immunosuppressive tumor microenvironment to combat immunotherapy resistance: From mechanistic insights to therapeutic strategies
inferred← citeshttps://doi.org/10.1016/j.isci.2026.115079openalex-snapshot
A hereditary rat model of umbilical hernia: characterization, susceptibility locus mapping, and mechanism exploration
inferred← citeshttps://doi.org/10.1016/j.jconrel.2025.114340openalex-snapshot
Structure-guided design and engineering of a biparatopic antibody targeting CCR2 in triple negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.jep.2023.116834openalex-snapshot
Traditional Chinese medicine Kuan-Sin-Yin decoction inhibits cell mobility via downregulation of CCL2, CEACAM1 and PIK3R3 in hepatocellular carcinoma cells
inferred← citeshttps://doi.org/10.1016/j.jep.2024.118491openalex-snapshot
A literature review on signaling pathways of cervical cancer cell death-apoptosis induced by Traditional Chinese Medicine
inferred← citeshttps://doi.org/10.1016/j.jep.2026.121547openalex-snapshot
Deziyangxin suppresses non-small cell lung cancer through remodeling of the tumor immune microenvironment
inferred← citeshttps://doi.org/10.1016/j.jmb.2026.170013openalex-snapshot
Characterizing CCR2 Homodimers Using Homology-derived and AI-predicted Interfaces
inferred← citeshttps://doi.org/10.1016/j.jmii.2025.02.003openalex-snapshot
Role of CCL2/CCR2 axis in pulmonary fibrosis induced by respiratory viruses
inferred← citeshttps://doi.org/10.1016/j.jncc.2024.09.001openalex-snapshot
Osteoimmunology in bone malignancies: a symphony with evil
inferred← citeshttps://doi.org/10.1016/j.jvir.2023.11.021openalex-snapshot
Pulsed Electric Field Ablation versus Radiofrequency Thermal Ablation in Murine Breast Cancer Models: Anticancer Immune Stimulation, Tumor Response, and Abscopal Effects
inferred← citeshttps://doi.org/10.1016/j.mad.2024.112009openalex-snapshot
Role of chemokines in aging and age-related diseases
inferred← citeshttps://doi.org/10.1016/j.mcn.2026.104093openalex-snapshot
Glial-neuronal interactions via chemokine signaling in cerebral ischemia: Mechanisms and therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.molliq.2024.124218openalex-snapshot
Mechanistic insights into inhibition of CCL2-guided leukocyte recruitment by oxyresveratrol and its derivatives
inferred← citeshttps://doi.org/10.1016/j.nbd.2024.106635openalex-snapshot
Hsp90aa1/JUN/Ccl2 regulatory axis mediates migration and differentiation of NSPCs, promoting the onset and progression of early post-ischemic stroke epilepsy
inferred← citeshttps://doi.org/10.1016/j.omtn.2023.102053openalex-snapshot
Tumor-targeted delivery of lnc antisense RNA against RCAS1 by live-attenuated tryptophan-auxotrophic Salmonella inhibited 4T1 breast tumors and metastasis in mice
inferred← citeshttps://doi.org/10.1016/j.phrs.2025.107890openalex-snapshot
Extracellular vesicles: A new frontier in deciphering the mechanisms of traditional Chinese medicine
inferred← citeshttps://doi.org/10.1016/j.prp.2026.156621openalex-snapshot
Recent advances in understanding the role of chemokines in breast cancer microenvironment remodelling
inferred← citeshttps://doi.org/10.1016/j.tranon.2026.102746openalex-snapshot
CCL2: A double-edged sword in neuroblastoma, with a critical role in MYCN-amplified tumors
inferred← citeshttps://doi.org/10.1016/j.xcrm.2026.102775openalex-snapshot
Predicting glioma survival and extracellular matrix remodeling through MRI radiogenomics
inferred← citeshttps://doi.org/10.1021/acs.bioconjchem.5c00181openalex-snapshot
Design and Evaluation of Stable Cysteine-Modified Monobody Scaffolds for Mirror-Image Synthesis
inferred← citeshttps://doi.org/10.1021/acscentsci.4c01249openalex-snapshot
Late-Stage Minimal Labeling of Peptides and Proteins for Real-Time Imaging of Cellular Trafficking
inferred← citeshttps://doi.org/10.1021/acsnano.3c06194openalex-snapshot
A Trisulfide Bond Containing Biodegradable Polymer Delivering Pt(IV) Prodrugs to Deplete Glutathione and Donate H2S to Boost Chemotherapy and Antitumor Immunity
inferred← citeshttps://doi.org/10.1021/acsnano.3c09201openalex-snapshot
MRI Detection of Lymph Node Metastasis through Molecular Targeting of C–C Chemokine Receptor Type 2 and Monocyte Hitchhiking
inferred← citeshttps://doi.org/10.1021/acsptsci.3c00303openalex-snapshot
Chemokine Receptor 2 Targeted PET/CT Imaging Distant Metastases in Pancreatic Ductal Adenocarcinoma
inferred← citeshttps://doi.org/10.1021/jacs.6c05055openalex-snapshot
Automated Parallel Synthesis Accelerates Virtual Screening Hit Discovery
inferred← citeshttps://doi.org/10.1038/s41388-023-02934-wopenalex-snapshot
IFI35 limits antitumor immunity in triple-negative breast cancer via CCL2 secretion
inferred← citeshttps://doi.org/10.1038/s41388-024-03100-6openalex-snapshot
PIM1/NF-κB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC
inferred← citeshttps://doi.org/10.1038/s41388-025-03370-8openalex-snapshot
Suprabasin promotes gastric cancer liver metastasis via hepatic stellate cells-mediated EGF/CCL2/JAK2 intercellular signaling pathways
inferred← citeshttps://doi.org/10.1038/s41392-024-01826-zopenalex-snapshot
Development of pharmacological immunoregulatory anti-cancer therapeutics: current mechanistic studies and clinical opportunities
inferred← citeshttps://doi.org/10.1038/s41392-024-01868-3openalex-snapshot
Targeting cytokine and chemokine signaling pathways for cancer therapy
inferred← citeshttps://doi.org/10.1038/s41392-024-01937-7openalex-snapshot
Pre-metastatic niche: formation, characteristics and therapeutic implication
inferred← citeshttps://doi.org/10.1038/s41392-026-02998-6openalex-snapshot
Myeloid-derived suppressor cells in cancer: biology, regulatory networks and theranostic prospects
inferred← citeshttps://doi.org/10.1038/s41467-023-36109-8openalex-snapshot
HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC
inferred← citeshttps://doi.org/10.1038/s41577-025-01229-3openalex-snapshot
Microenvironmental regulation of solid tumour resistance to CAR T cell therapy
inferred← citeshttps://doi.org/10.1038/s41598-023-46968-2openalex-snapshot
Anti-CCL2 antibody combined with etoposide prolongs survival in a minimal residual disease mouse model of neuroblastoma
inferred← citeshttps://doi.org/10.1038/s41598-025-04862-zopenalex-snapshot
Machine learning and multi-omics analysis reveal key regulators of proneural–mesenchymal transition in glioblastoma
inferred← citeshttps://doi.org/10.1038/s41598-025-32222-4openalex-snapshot
Blockade of CC chemokine receptor 2 suppresses pancreatic cancer progression through the interaction with macrophages in the tumor microenvironment
inferred← citeshttps://doi.org/10.1038/s42003-023-04983-zopenalex-snapshot
Navoximod modulates local HSV-1 replication to reshape tumor immune microenvironment for enhanced immunotherapy via an injectable hydrogel
inferred← citeshttps://doi.org/10.1038/s43588-025-00809-6openalex-snapshot
Interpretable niche-based cell‒cell communication inference using multi-view graph neural networks
inferred← citeshttps://doi.org/10.1039/d5nr03762jopenalex-snapshot
In situ programming of CAR-macrophages via a polyplex nanomaterial and STING activation for triple-negative breast cancer immunotherapy
inferred← citeshttps://doi.org/10.1039/d5nr05009jopenalex-snapshot
Targeting obesity and adipokine signaling in the breast cancer microenvironment for enhanced tumor therapy
inferred← citeshttps://doi.org/10.1042/cs20257214openalex-snapshot
Chemokine receptors in vascular biology: a review of current evidence, implications, and therapeutic targets for hypertension
inferred← citeshttps://doi.org/10.1080/10255842.2026.2631138openalex-snapshot
Bioinformatics analysis unveils hub genes in the pathogenesis of sevoflurane anesthesia-induced respiratory depression
inferred← citeshttps://doi.org/10.1080/1061186x.2024.2384071openalex-snapshot
Targeting anticancer immunity in melanoma tumour microenvironment: unleashing the potential of adjuvants, drugs, and phytochemicals
inferred← citeshttps://doi.org/10.1080/14712598.2022.2087471openalex-snapshot
Prospects of cell chemotactic factors in bone and cartilage tissue engineering
inferred← citeshttps://doi.org/10.1080/15257770.2025.2584080openalex-snapshot
P2Y6 receptor inhibition arrests tumor cell progression in a mouse lymphoma model
inferred← citeshttps://doi.org/10.1080/15384047.2023.2205342openalex-snapshot
CCL2 promotes lymphatic metastasis via activating RhoA and Rac1 pathway and predict prognosis to some extent in tongue cancer
inferred← citeshttps://doi.org/10.1080/15384101.2025.2606113openalex-snapshot
Identification of mitochondrial permeability transition-related gene signatures to predict lung adenocarcinoma survival and drug response
inferred← citeshttps://doi.org/10.1080/1744666x.2024.2326626openalex-snapshot
Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma
inferred← citeshttps://doi.org/10.1080/19490976.2026.2647602openalex-snapshot
Circadian synchronization between diet and gut microbiota in modulating host's health
inferred← citeshttps://doi.org/10.1089/mab.2021.0063openalex-snapshot
Development of a Novel Anti-Mouse CCR2 Monoclonal Antibody (C 2 Mab-6) by N-Terminal Peptide Immunization
inferred← citeshttps://doi.org/10.1089/mab.2022.0001openalex-snapshot
Development of an Anti-human CCR2 Monoclonal Antibody (C 2 Mab-9) by N-Terminal Peptide Immunization
inferred← citeshttps://doi.org/10.1093/cvr/cvac132openalex-snapshot
Mechanisms shared between cancer, heart failure, and targeted anti-cancer therapies
inferred← citeshttps://doi.org/10.1093/intbio/zyaf020openalex-snapshot
Explicating miRNA-mediated regulation of inflammatory pathways in COPD, MS, and lung cancer using explainable artificial intelligence: insights from peripheral blood profiles
inferred← citeshttps://doi.org/10.1093/jleuko/qiae162openalex-snapshot
Enhanced CCR2 expression by ACKR2-deficient NK cells increases tumoricidal cell therapy efficacy
inferred← citeshttps://doi.org/10.1093/jpp/rgad112openalex-snapshot
Targeting the CCL2–CCR2 signaling pathway: potential implications of statins beyond cardiovascular diseases
inferred← citeshttps://doi.org/10.1097/hc9.0000000000000508openalex-snapshot
GATA4 downregulation enhances CCL20-mediated immunosuppression in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1097/hep.0000000000001185openalex-snapshot
Tumor-derived CCL2 drives tumor growth and immunosuppression in IDH1-mutant cholangiocarcinoma
inferred← citeshttps://doi.org/10.1097/j.pain.0000000000003090openalex-snapshot
A phenotypic screening platform for chronic pain therapeutics using all-optical electrophysiology
inferred← citeshttps://doi.org/10.1097/js9.0000000000004053openalex-snapshot
The impact of COVID-19 on the treatment and prognosis of cancer patients
inferred← citeshttps://doi.org/10.1097/md.0000000000033823openalex-snapshot
Bioinformatic analysis of biological changes involved in pelvic organ prolapse
inferred← citeshttps://doi.org/10.1097/md.0000000000035613openalex-snapshot
Role of MCP-1/CCR2 axis in renal fibrosis: Mechanisms and therapeutic targeting
inferred← citeshttps://doi.org/10.1097/md.0000000000037642openalex-snapshot
Development and validation of a pyroptosis-related prognostic signature associated with osteosarcoma metastasis and immune infiltration
inferred← citeshttps://doi.org/10.1097/md.0000000000043489openalex-snapshot
Study on identification and analysis of biomarkers related to neutrophils extracellular traps in childhood asthma
inferred← citeshttps://doi.org/10.1101/2023.11.15.567150openalex-snapshot
Molecular determinants of antagonist interactions with chemokine receptors CCR2 and CCR5
inferred← citeshttps://doi.org/10.1101/2024.03.01.583061openalex-snapshot
CHEMOKINE SIGNALING IN BREAST CANCER: FOCUS ON CC-MOTIF CHEMOKINE LIGANDS
inferred← citeshttps://doi.org/10.1101/2024.05.29.596531openalex-snapshot
CCR2 silencing in sensory neurons blocks bone cancer progression
inferred← citeshttps://doi.org/10.1101/2024.07.19.604341openalex-snapshot
TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers
inferred← citeshttps://doi.org/10.1101/2024.09.04.611306openalex-snapshot
A Graph Curvature-Based Pipeline for Discovering Immune Checkpoint Response Biomarkers
inferred← citeshttps://doi.org/10.1111/1759-7714.15394openalex-snapshot
Causal relationships between immune cell phenotypes and lung adenocarcinoma: A bidirectional two‐sample Mendelian randomization study
inferred← citeshttps://doi.org/10.1111/1759-7714.15398openalex-snapshot
PRPS2‐mediated modulation of the antitumor immune response in lung cancer through CCL2 ‐mediated tumor‐associated macrophages and myeloid‐derived suppressor cells
inferred← citeshttps://doi.org/10.1111/bph.70102openalex-snapshot
GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger
inferred← citeshttps://doi.org/10.1111/bph.70295openalex-snapshot
PLAGL2 promotes HCC progression by recruiting tumour‐associated macrophages via CCL2/CCR2 signalling
inferred← citeshttps://doi.org/10.1111/cas.70558openalex-snapshot
Angiogenic and Stromal Remodeling Associated With Aggressive Fibrosarcomatous Dermatofibrosarcoma Protuberans
inferred← citeshttps://doi.org/10.1111/cpr.13570openalex-snapshot
Cisplatin‐induced oxPAPC release enhances MDSCs infiltration into LL2 tumour tissues through MCP‐1/CCL2 and LTB4/LTB4R pathways
inferred← citeshttps://doi.org/10.1111/cpr.13740openalex-snapshot
Oncolytic herpes simplex virus propagates tertiary lymphoid structure formation via CXCL10 / CXCR3 to boost antitumor immunity
inferred← citeshttps://doi.org/10.1111/crj.70038openalex-snapshot
Causal Association Between Monounsaturated Fatty Acids and Lung Cancer: A Two‐Sample Mendelian Randomization Study
inferred← citeshttps://doi.org/10.1111/imm.70064openalex-snapshot
Leukocyte Specific Protein 1 Deficiency Impairs Anti‐Melanoma Immunity by Disrupting DC and CD8 + T Cell Function in Mice
inferred← citeshttps://doi.org/10.1111/imm.70103openalex-snapshot
Bidirectional Regulation in the Tumour Microenvironment: The Interaction Between Tumour‐Associated Macrophages and T Cells Reshapes the Paradigm of Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1111/imr.13287openalex-snapshot
The cell stress and immunity cycle in cancer: Toward next generation of cancer immunotherapy
inferred← citeshttps://doi.org/10.1111/imr.70052openalex-snapshot
Innate Immunity and Tertiary Lymphoid Structures
inferred← citeshttps://doi.org/10.1111/jcmm.70300openalex-snapshot
CCL2 / CCR2 Signalling in Mesenchymal Stem/Progenitor Cell Recruitment and Fracture Healing in Mice
inferred← citeshttps://doi.org/10.1111/jcpe.13872openalex-snapshot
CCL2 is a key regulator and therapeutic target for periodontitis
inferred← citeshttps://doi.org/10.1111/vco.13056openalex-snapshot
Evaluation of Serum Level of Chemokine (C‐C Motif) Ligand 2 ( CCL2 ) in Canine Urothelial Carcinomas, Mast Cell Tumours, and Insulinomas, and Its Correlation With Circulating Monocytes
inferred← citeshttps://doi.org/10.1126/sciadv.adx2988openalex-snapshot
Immunosuppressive macrophages determine the effect of cellular senescence on tumor progression
inferred← citeshttps://doi.org/10.1126/scisignal.abo4314openalex-snapshot
The dual-function chemokine receptor CCR2 drives migration and chemokine scavenging through distinct mechanisms
inferred← citeshttps://doi.org/10.1134/s123456782560035xopenalex-snapshot
The Doxorubicin-Induced Myocardial Injury Model in Rodents: A Paradigm Shift?
inferred← citeshttps://doi.org/10.1134/s2079086422040053openalex-snapshot
Chemokine CCL2 and Its Receptor CCR2 in Regulation of Cognitive Functions and in Development of Aging Diseases
inferred← citeshttps://doi.org/10.1136/gutjnl-2024-332535openalex-snapshot
Integration of lipidomics with targeted, single cell, and spatial transcriptomics defines an unresolved pro-inflammatory state in colon cancer
inferred← citeshttps://doi.org/10.1136/jitc-2022-006493openalex-snapshot
T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1136/jitc-2025-014681openalex-snapshot
Inhibition of histone demethylase LSD1 suppresses CD47 expression and enhances efficacy of CD47 blockade in breast cancer
inferred← citeshttps://doi.org/10.1142/s2737416524500819openalex-snapshot
Understanding the Relationship between MCP-1 SNP (rs1024611) and VEGF SNP (rs699947) with Aging and Lifestyle Habits via Computational Insights
inferred← citeshttps://doi.org/10.1146/annurev-cancerbio-061421-040258openalex-snapshot
Strategies for Heating Up Cold Tumors to Boost Immunotherapies
inferred← citeshttps://doi.org/10.1146/annurev-pharmtox-062124-043519openalex-snapshot
Neuroinflammation and Disease: Pathways and Opportunities
inferred← citeshttps://doi.org/10.1152/ajpcell.00712.2024openalex-snapshot
HOXA3 activates USP15 to suppress autophagy and promote M2-type macrophage polarization in renal cell carcinoma via facilitating the deubiquitination of SQSTM1
inferred← citeshttps://doi.org/10.1152/ajpcell.00834.2025openalex-snapshot
Tumor-associated macrophages: orchestrators of the tumor microenvironment
inferred← citeshttps://doi.org/10.1155/2021/7842035openalex-snapshot
BDNF Acts as a Prognostic Factor Associated with Tumor-Infiltrating Th2 Cells in Pancreatic Adenocarcinoma
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