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Positioning sulphonylureas in a modern treatment algorithm for patients with type 2 diabetes: Expert opinion from a European consensus panel

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.2018.18269openalex-snapshot
Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk
inferredcites →https://doi.org/10.1007/s11892-014-0473-5openalex-snapshot
Sulfonylureas: A New Look at Old Therapy
inferredcites →https://doi.org/10.1016/j.amepre.2013.04.017openalex-snapshot
Lifetime Direct Medical Costs of Treating Type 2 Diabetes and Diabetic Complications
inferredcites →https://doi.org/10.1016/j.diabres.2019.02.014openalex-snapshot
Meta-analyses of the effects of DPP-4 inhibitors, SGLT2 inhibitors and GLP1 receptor analogues on cardiovascular death, myocardial infarction, stroke and hospitalization for heart failure
inferredcites →https://doi.org/10.1016/j.diabres.2019.107785openalex-snapshot
The future of new drugs for diabetes management
inferredcites →https://doi.org/10.1016/j.diabres.2019.107836openalex-snapshot
The right place for Sulphonylureas today: Part of ‘Review the Series: Implications of recent CVOTs in Type 2 diabetes mellitus’
inferredcites →https://doi.org/10.1016/j.ecl.2017.10.002openalex-snapshot
Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes Mellitus
inferredcites →https://doi.org/10.1016/j.jacc.2018.07.071openalex-snapshot
The Changing Landscape of Diabetes Therapy for Cardiovascular Risk Reduction
inferredcites →https://doi.org/10.1016/j.pcd.2019.01.003openalex-snapshot
Network meta-analysis of nine large cardiovascular outcome trials of new antidiabetic drugs
inferredcites →https://doi.org/10.1016/s0140-6736(18)32590-xopenalex-snapshot
SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials
inferredcites →https://doi.org/10.1016/s0140-6736(18)32840-xopenalex-snapshot
Real-world studies no substitute for RCTs in establishing efficacy
inferredcites →https://doi.org/10.1016/s0140-6736(19)31149-3openalex-snapshot
Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial
inferredcites →https://doi.org/10.1016/s0300-7073(12)70593-5openalex-snapshot
Management of Hyperglycemia in Type 2 Diabetes
inferredcites →https://doi.org/10.1016/s2213-8587(17)30317-0openalex-snapshot
Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial
inferredcites →https://doi.org/10.1016/s2213-8587(18)30025-1openalex-snapshot
Do sulphonylureas still have a place in clinical practice?
inferredcites →https://doi.org/10.1016/s2213-8587(20)30038-3openalex-snapshot
Glucose-lowering drugs or strategies, atherosclerotic cardiovascular events, and heart failure in people with or at risk of type 2 diabetes: an updated systematic review and meta-analysis of randomised cardiovascular outcome trials
inferredcites →https://doi.org/10.1056/nejmoa0802987openalex-snapshot
Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes
inferredcites →https://doi.org/10.1056/nejmoa1811744openalex-snapshot
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
inferredcites →https://doi.org/10.1080/00325481.2019.1578590openalex-snapshot
Management of hypoglycemia in older adults with type 2 diabetes
inferredcites →https://doi.org/10.1093/eurheartj/ehv301openalex-snapshot
Risk of hospitalization for heart failure in patients with type 2 diabetes newly treated with DPP-4 inhibitors or other oral glucose-lowering medications: a retrospective registry study on 127,555 patients from the Nationwide OsMed Health-DB Database
inferredcites →https://doi.org/10.1111/dom.12306openalex-snapshot
Combination therapy with metformin plus sulphonylureas versus metformin plus DPP ‐4 inhibitors: association with major adverse cardiovascular events and all‐cause mortality
inferredcites →https://doi.org/10.1111/dom.12314openalex-snapshot
Cardiovascular safety of combination therapies with incretin‐based drugs and metformin compared with a combination of metformin and sulphonylurea in type 2 diabetes mellitus – a retrospective nationwide study
inferredcites →https://doi.org/10.1111/dom.13710openalex-snapshot
Real‐world prevalence of the inclusion criteria for the LEADER trial: Data from a national general practice network
inferredcites →https://doi.org/10.1111/dom.13962openalex-snapshot
Enrolment criteria for diabetes cardiovascular outcome trials do not inform on generalizability to clinical practice: The case of glucagon‐like peptide‐1 receptor agonists
inferredcites →https://doi.org/10.1111/j.1365-2362.2004.01381.xopenalex-snapshot
GUIDE study: double‐blind comparison of once‐daily gliclazide MR and glimepiride in type 2 diabetic patients
inferredcites →https://doi.org/10.1111/jgs.15767openalex-snapshot
American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults
inferredcites →https://doi.org/10.1136/bmj.b4731openalex-snapshot
Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database
inferredcites →https://doi.org/10.1136/bmj.i3625openalex-snapshot
Risk of hypoglycaemia in users of sulphonylureas compared with metformin in relation to renal function and sulphonylurea metabolite group: population based cohort study
inferredcites →https://doi.org/10.1136/bmjdrc-2018-000627openalex-snapshot
Eligibility of patients with type 2 diabetes for sodium–glucose cotransporter 2 inhibitor cardiovascular outcomes trials: a global perspective from the DISCOVER study
inferredcites →https://doi.org/10.1161/circresaha.115.306884openalex-snapshot
Vascular Complications of Diabetes
inferredcites →https://doi.org/10.1177/1479164113490765openalex-snapshot
Individualized glycaemic targets and pharmacotherapy in type 2 diabetes
inferredcites →https://doi.org/10.1186/s12933-017-0574-yopenalex-snapshot
Comparative effects of microvascular and macrovascular disease on the risk of major outcomes in patients with type 2 diabetes
inferredcites →https://doi.org/10.1371/journal.pone.0082880openalex-snapshot
Safety and Efficacy of Gliclazide as Treatment for Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Trials
inferredcites →https://doi.org/10.2337/dc08-0167openalex-snapshot
Is the Combination of Sulfonylureas and Metformin Associated With an Increased Risk of Cardiovascular Disease or All-Cause Mortality?
inferredcites →https://doi.org/10.2337/dc17-0595openalex-snapshot
Pharmacologic Differences of Sulfonylureas and the Risk of Adverse Cardiovascular and Hypoglycemic Events
inferredcites →https://doi.org/10.2337/dc19-s010openalex-snapshot
10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2019
inferredcites →https://doi.org/10.2337/dc20-s009openalex-snapshot
9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2020
inferredcites →https://doi.org/10.2337/dc20-s010openalex-snapshot
10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2020
inferredcites →https://doi.org/10.2337/dci18-0012openalex-snapshot
The Cost of Diabetes Care—An Elephant in the Room
inferredcites →https://doi.org/10.2337/dci18-0033openalex-snapshot
Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
inferredcites →https://doi.org/10.2337/dci19-0034openalex-snapshot
A Verdict for Glimepiride: Effective and Not Guilty of Cardiovascular Harm
inferredcites →https://doi.org/10.2337/dci19-0066openalex-snapshot
2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
inferredcites →https://doi.org/10.2337/diacare.12.3.203openalex-snapshot
Symptomatic Hypoglycemia in NIDDM Patients Treated With Oral Hypoglycemic Agents
inferredcites →https://doi.org/10.2337/diaspect.27.2.82openalex-snapshot
A Brief History of the Development of Diabetes Medications
inferredcites →https://doi.org/10.4103/ijem.ijem_556_17openalex-snapshot
Consensus recommendations on sulfonylurea and sulfonylurea combinations in the management of Type 2 diabetes mellitus – International Task Force
inferredcites →https://doi.org/10.4158/cs-2018-0535openalex-snapshot
Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Comprehensive Type 2 Diabetes Management Algorithm – 2019 Executive Summary
inferredcites →https://doi.org/10.4158/ep151126.csopenalex-snapshot
Consensus Statement By The American Association Of Clinical Endocrinologists And American College Of Endocrinology On The Comprehensive Type 2 Diabetes Management Algorithm – 2016 EXECUTIVE SUMMARY

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4765193openalex-extracted
Synergistic Effects of Sulfonylureas with Chemotherapeutics: In Vitro Screening Reveals Enhanced Cytotoxicity of Doxorubicin in Combination with Sulfonylureas
inferred← citeshttps://doi.org/10.1002/mco2.70588openalex-snapshot
Loss of Beta‐Cell Identity and Function as a Mechanism of Secondary Failure of Sulfonylurea Therapy in Diabetes
inferred← citeshttps://doi.org/10.1007/s11428-021-00822-zopenalex-snapshot
Diabetestherapie bei fortgeschrittenen Lebererkrankungen und Leberzirrhose
inferred← citeshttps://doi.org/10.1007/s13300-021-01137-4openalex-snapshot
Identification of the Inappropriate Clinical Actions (DON'T) to Improve the Management of Patients with Type 2 Diabetes Failing Basal Insulin Supported Oral Treatment: Results of Survey for a Panel of Diabetes Specialists in Italy
inferred← citeshttps://doi.org/10.1007/s42000-025-00734-3openalex-snapshot
Current treatment for diabetes: a holistic approach
inferred← citeshttps://doi.org/10.1016/j.deman.2021.100002openalex-snapshot
Sulphonylureas in the management of type 2 diabetes: To be or not to be?
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2022.11.038openalex-snapshot
An investigation into the potential action of polyphenols against human Islet Amyloid Polypeptide aggregation in type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.mmm.2020.11.001openalex-snapshot
Existe-t-il encore une place pour les sulfamides hypoglycémiants dans le traitement du diabète de type 2 en 2021 ?
inferred← citeshttps://doi.org/10.1016/j.numecd.2021.06.006openalex-snapshot
Initial treatment of diabetes in Italy. A nationwide population-based study from of the ARNO Diabetes Observatory
inferred← citeshttps://doi.org/10.1080/14656566.2021.1909570openalex-snapshot
Considerations for single- versus multiple-drug pharmacotherapy in the management of painful diabetic neuropathy
inferred← citeshttps://doi.org/10.1080/14656566.2021.1999413openalex-snapshot
The role of sulfonylureas in the treatment of type 2 diabetes
inferred← citeshttps://doi.org/10.1080/14656566.2022.2141108openalex-snapshot
Evaluating gliclazide for the treatment of type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1111/dom.14675openalex-snapshot
Preventing all‐cause hospitalizations in type 2 diabetes with sodium‐glucose cotransporter‐2 inhibitors and glucagon‐like peptide ‐1 receptor agonists: A narrative review and proposed clinical approach
inferred← citeshttps://doi.org/10.1111/dom.16632openalex-snapshot
Loss of β‐cell identity in human islets treated with glibenclamide
inferred← citeshttps://doi.org/10.1177/11795514221074663openalex-snapshot
Position of Sulfonylureas in the Current ERA: Review of National and International Guidelines
inferred← citeshttps://doi.org/10.1186/s12933-022-01600-xopenalex-snapshot
Time-resolved trajectory of glucose lowering medications and cardiovascular outcomes in type 2 diabetes: a recurrent neural network analysis
inferred← citeshttps://doi.org/10.1210/clinem/dgab849openalex-snapshot
New Horizons: Next-Generation Insulin Analogues: Structural Principles and Clinical Goals
inferred← citeshttps://doi.org/10.18203/2349-3933.ijam20220442openalex-snapshot
Utility and benefits of sulfonylureas beyond glycemic control
inferred← citeshttps://doi.org/10.2147/dmso.s390075openalex-snapshot
Efficacy of Dapagliflozin in Southern Europe Across the Spectrum of Characteristics of Type 2 Diabetes: An International Real-World Analysis
inferred← citeshttps://doi.org/10.24121/dh.2022.23openalex-snapshot
A 2-es típusú diabetes mellitus antihiperglikémiás kezelésének változása Magyarországon 2015–2020 között – adatbáziselemzés országos adatai
inferred← citeshttps://doi.org/10.3390/ijms242417147openalex-snapshot
Drug Therapies for Diabetes
inferred← citeshttps://doi.org/10.3390/ijms26062770openalex-snapshot
Unraveling the Mystery of Insulin Resistance: From Principle Mechanistic Insights and Consequences to Therapeutic Interventions
inferred← citeshttps://doi.org/10.3390/medicina58101382openalex-snapshot
Changing Patterns of Antihyperglycaemic Treatment among Patients with Type 2 Diabetes in Hungary between 2015 and 2020—Nationwide Data from a Register-Based Analysis
inferred← citeshttps://doi.org/10.3390/pharmaceutics17060777openalex-snapshot
Revolutionizing Diabetes Management Through Nanotechnology-Driven Smart Systems
inferred← citeshttps://doi.org/10.36290/vnl.2025.026openalex-snapshot
Treatment of type 2 diabetes mellitus - a current view of the different drug classes and strategies for their use
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