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Structural basis for the Target DNA recognition and binding by the MYB domain of phosphate starvation response 1

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s00018-012-1090-6openalex-snapshot
Transcriptional regulation of phosphate acquisition by higher plants
inferredcites →https://doi.org/10.1016/j.febslet.2012.01.036openalex-snapshot
Phosphate homeostasis in the yeast Saccharomyces cerevisiae, the key role of the SPX domain‐containing proteins
inferredcites →https://doi.org/10.1016/j.jmb.2007.05.022openalex-snapshot
Inference of Macromolecular Assemblies from Crystalline State
inferredcites →https://doi.org/10.1016/j.tplants.2010.06.005openalex-snapshot
MYB transcription factors in Arabidopsis
inferredcites →https://doi.org/10.1016/s1369-5266(00)00062-5openalex-snapshot
Phosphate transport and signaling
inferredcites →https://doi.org/10.1016/s1369-5266(00)80063-1openalex-snapshot
Phosphate transport and signaling
inferredcites →https://doi.org/10.1034/j.1399-3054.2002.1150101.xopenalex-snapshot
Phosphate sensing in higher plants
inferredcites →https://doi.org/10.1046/j.1365-2958.2003.03562.xopenalex-snapshot
Arg82p is a bifunctional protein whose inositol polyphosphate kinase activity is essential for nitrogen and PHO gene expression but not for Mcm1p chaperoning in yeast
inferredcites →https://doi.org/10.1046/j.1365-313x.1994.6050673.xopenalex-snapshot
The Arabidopsis ribonuclease gene RNS1 is tightly controlled in response to phosphate limitation
inferredcites →https://doi.org/10.1073/pnas.1404654111openalex-snapshot
SPX1 is a phosphate-dependent inhibitor of PHOSPHATE STARVATION RESPONSE 1 in Arabidopsis
inferredcites →https://doi.org/10.1073/pnas.1404680111openalex-snapshot
Rice SPX1 and SPX2 inhibit phosphate starvation responses through interacting with PHR2 in a phosphate-dependent manner
inferredcites →https://doi.org/10.1074/jbc.m113.482281openalex-snapshot
Arabidopsis Ferritin 1 (AtFer1) Gene Regulation by the Phosphate Starvation Response 1 (AtPHR1) Transcription Factor Reveals a Direct Molecular Link between Iron and Phosphate Homeostasis
inferredcites →https://doi.org/10.1074/jbc.m405398200openalex-snapshot
Low Affinity Orthophosphate Carriers Regulate PHO Gene Expression Independently of Internal Orthophosphate Concentration in Saccharomyces cerevisiae
inferredcites →https://doi.org/10.1093/bioinformatics/15.4.305openalex-snapshot
ESPript: analysis of multiple sequence alignments in PostScript.
inferredcites →https://doi.org/10.1093/jxb/erh009openalex-snapshot
The transcriptional control of plant responses to phosphate limitation
inferredcites →https://doi.org/10.1093/jxb/ern115openalex-snapshot
Transcript profiling of Zea mays roots reveals gene responses to phosphate deficiency at the plant- and species-specific levels
inferredcites →https://doi.org/10.1093/jxb/ert444openalex-snapshot
Coordination between zinc and phosphate homeostasis involves the transcription factor PHR1, the phosphate exporter PHO1, and its homologue PHO1;H3 in Arabidopsis
inferredcites →https://doi.org/10.1093/jxb/eru535openalex-snapshot
The transcription factor PHR1 regulates lipid remodeling and triacylglycerol accumulation in Arabidopsis thaliana during phosphorus starvation
inferredcites →https://doi.org/10.1101/gad.204401openalex-snapshot
A conserved MYB transcription factor involved in phosphate starvation signaling both in vascular plants and in unicellular algae
inferredcites →https://doi.org/10.1104/pp.103.020941openalex-snapshot
Changes in Gene Expression in Arabidopsis Shoots during Phosphate Starvation and the Potential for Developing Smart Plants
inferredcites →https://doi.org/10.1104/pp.103.021022openalex-snapshot
Phosphate Starvation Triggers Distinct Alterations of Genome Expression in Arabidopsis Roots and Leaves
inferredcites →https://doi.org/10.1104/pp.106.079707openalex-snapshot
PHO2, MicroRNA399, and PHR1 Define a Phosphate-Signaling Pathway in Plants
inferredcites →https://doi.org/10.1104/pp.107.096958openalex-snapshot
Phosphorus Stress in Common Bean: Root Transcript and Metabolic Responses
inferredcites →https://doi.org/10.1104/pp.112.209254openalex-snapshot
An RNA-Seq Transcriptome Analysis of Orthophosphate-Deficient White Lupin Reveals Novel Insights into Phosphorus Acclimation in Plants
inferredcites →https://doi.org/10.1104/pp.114.237990openalex-snapshot
A Shoot-Specific Hypoxic Response of Arabidopsis Sheds Light on the Role of the Phosphate-Responsive Transcription Factor PHOSPHATE STARVATION RESPONSE1
inferredcites →https://doi.org/10.1104/pp.15.01336openalex-snapshot
Arabidopsis PHL2 and PHR1 Act Redundantly as the Key Components of the Central Regulatory System Controlling Transcriptional Responses to Phosphate Starvation
inferredcites →https://doi.org/10.1104/pp.87.3.711openalex-snapshot
Phosphate Starvation Inducible Metabolism in Lycopersicon esculentum
inferredcites →https://doi.org/10.1104/pp.87.3.716openalex-snapshot
Phosphate Starvation Inducible Metabolism in Lycopersicon esculentum
inferredcites →https://doi.org/10.1105/tpc.002733openalex-snapshot
Molecular Structure of the GARP Family of Plant Myb-Related DNA Binding Motifs of the Arabidopsis Response Regulators
inferredcites →https://doi.org/10.1105/tpc.113.117325openalex-snapshot
Spatio-Temporal Transcript Profiling of Rice Roots and Shoots in Response to Phosphate Starvation and Recovery
inferredcites →https://doi.org/10.1107/s0021889807021206openalex-snapshot
Phaser crystallographic software
inferredcites →https://doi.org/10.1107/s0907444909042073openalex-snapshot
MolProbity : all-atom structure validation for macromolecular crystallography
inferredcites →https://doi.org/10.1107/s0907444909042589openalex-snapshot
Molecular replacement with MOLREP
inferredcites →https://doi.org/10.1107/s0907444909047337openalex-snapshot
XDS
inferredcites →https://doi.org/10.1107/s0907444909052925openalex-snapshot
PHENIX : a comprehensive Python-based system for macromolecular structure solution
inferredcites →https://doi.org/10.1107/s0907444910007493openalex-snapshot
Features and development of Coot
inferredcites →https://doi.org/10.1107/s0907444910045749openalex-snapshot
Overview of the CCP 4 suite and current developments
inferredcites →https://doi.org/10.1107/s0907444911001314openalex-snapshot
REFMAC 5 for the refinement of macromolecular crystal structures
inferredcites →https://doi.org/10.1107/s0907444913015308openalex-snapshot
Decision making inxia2
inferredcites →https://doi.org/10.1107/s0907444998004119openalex-snapshot
Incorporation of Prior Phase Information Strengthens Maximum-Likelihood Structure Refinement
inferredcites →https://doi.org/10.1107/s0907444998006684openalex-snapshot
SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model
inferredcites →https://doi.org/10.1107/s2053230x16004684openalex-snapshot
The Myb domain of LUX ARRHYTHMO in complex with DNA: expression, purification and crystallization
inferredcites →https://doi.org/10.1107/s2059798316016697openalex-snapshot
Molecular symmetry-constrained systematic search approach to structure solution of the coiled-coil SRGAP2 F-BARx domain
inferredcites →https://doi.org/10.1111/j.1365-3040.2007.01734.xopenalex-snapshot
Increased expression of the MYB‐related transcription factor, PHR1, leads to enhanced phosphate uptake in Arabidopsis thaliana
inferredcites →https://doi.org/10.1111/j.1365-3040.2008.01883.xopenalex-snapshot
Essential role of MYB transcription factor: PvPHR1 and microRNA: PvmiR399 in phosphorus‐deficiency signalling in common bean roots
inferredcites →https://doi.org/10.1111/j.1399-3054.2011.01520.xopenalex-snapshot
The Arabidopsis transcription factor PHR1 is essential for adaptation to high light and retaining functional photosynthesis during phosphate starvation
inferredcites →https://doi.org/10.1126/science.1218231openalex-snapshot
Linking Crystallographic Model and Data Quality
inferredcites →https://doi.org/10.1146/annurev-arplant-042110-103849openalex-snapshot
Signaling Network in Sensing Phosphate Availability in Plants
inferredcites →https://doi.org/10.1186/1471-2229-11-19openalex-snapshot
The transcription factor PHR1 plays a key role in the regulation of sulfate shoot-to-root flux upon phosphate starvation in Arabidopsis
inferredcites →https://doi.org/10.1371/journal.pgen.1001102openalex-snapshot
A Central Regulatory System Largely Controls Transcriptional Activation and Repression Responses to Phosphate Starvation in Arabidopsis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4766567openalex-extracted
Egphl7, Egphr1 and Egphr2 Bind to P1bs and a Unique Motif, Agatwc, for Phosphate Starvation Transcriptional Regulation in Oil Palm
inferred← citeshttps://doi.org/10.1002/1873-3468.13902openalex-snapshot
MYB‐like transcription factor NoPSR1 is crucial for membrane lipid remodeling under phosphate starvation in the oleaginous microalga Nannochloropsis oceanica
inferred← citeshttps://doi.org/10.1002/pro.5214openalex-snapshot
The potent PHL4 transcription factor effector domain contains significant disorder
inferred← citeshttps://doi.org/10.1007/s00425-026-05034-7openalex-snapshot
Transcription factors in phosphorus utilization: enhancing crop productivity and stress resilience
inferred← citeshttps://doi.org/10.1016/j.indcrop.2026.123385openalex-snapshot
Phosphate availability shapes source–sink dynamics and nitrogen balance in dual-purpose hemp (Cannabis sativa L.): Insights from physiological and transcriptomic analyses
inferred← citeshttps://doi.org/10.1016/j.plantsci.2023.111723openalex-snapshot
Silencing of SlSPX1 and SlSPX2 promote growth and root mycorrhization in tomato (Solanum lycopersicum L.) seedlings
inferred← citeshttps://doi.org/10.1016/j.plgene.2026.100589openalex-snapshot
EgPHL7, EgPHR1 and EgPHR2 bind to the P1BS and a unique motif, AGATACT for transcriptional regulation of phosphate-starvation inducible genes in oil palm
inferred← citeshttps://doi.org/10.1016/j.str.2023.04.008openalex-snapshot
Structural insights into DarT toxin neutralization by cognate DarG antitoxin: ssDNA mimicry by DarG C-terminal domain keeps the DarT toxin inhibited
inferred← citeshttps://doi.org/10.1016/j.tplants.2022.12.008openalex-snapshot
Cracking the code of plant central phosphate signaling
inferred← citeshttps://doi.org/10.1016/j.tplants.2023.06.023openalex-snapshot
Plant-TFClass: a structural classification for plant transcription factors
inferred← citeshttps://doi.org/10.1016/j.xplc.2025.101627openalex-snapshot
PHR1-like 7 and phosphatidic acid oppositely regulate TAG degradation and seed oil accumulation in Arabidopsis
inferred← citeshttps://doi.org/10.1038/s41467-020-20681-4openalex-snapshot
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis
inferred← citeshttps://doi.org/10.1038/s41467-021-27391-5openalex-snapshot
Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure
inferred← citeshttps://doi.org/10.1038/s41467-022-29275-8openalex-snapshot
Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 – PHR2 complex
inferred← citeshttps://doi.org/10.1038/s41467-026-69810-5openalex-snapshot
The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA
inferred← citeshttps://doi.org/10.1073/pnas.2319335121openalex-snapshot
The structure of B-ARR reveals the molecular basis of transcriptional activation by cytokinin
inferred← citeshttps://doi.org/10.1093/advances/nmaa062openalex-snapshot
Perspective: Do Fasting, Caloric Restriction, and Diets Increase Sensitivity to Radiotherapy? A Literature Review
inferred← citeshttps://doi.org/10.1093/jxb/erag002openalex-snapshot
Phosphate starvation response 1 (PHR1): a versatile master regulator shaping plant resilience beyond phosphate deprivation
inferred← citeshttps://doi.org/10.1093/nar/gkz1081openalex-snapshot
Structural insights into target DNA recognition by R2R3-MYB transcription factors
inferred← citeshttps://doi.org/10.1093/plcell/koad326openalex-snapshot
Milestones in understanding transport, sensing, and signaling of the plant nutrient phosphorus
inferred← citeshttps://doi.org/10.1101/2019.12.13.875393openalex-snapshot
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis
inferred← citeshttps://doi.org/10.1101/2022.04.15.488190openalex-snapshot
Stepwise origin and evolution of a transcriptional activator and repressor system integrating nutrient signaling in plants
inferred← citeshttps://doi.org/10.1101/2025.09.18.677093openalex-snapshot
METABOLIC AND TRANSCRIPTOMIC ANALYSES IDENTIFY COORDINATED RESOURCE REALLOCATION IN RESPONSE TO PHOSPHATE SUPPLY IN HEMP
inferred← citeshttps://doi.org/10.1111/ppl.13831openalex-snapshot
Phosphorylation of S11 in PHR1 negatively controls its transcriptional activity
inferred← citeshttps://doi.org/10.1111/tpj.70589openalex-snapshot
The MAPK regulatory module TaMPKKK18 ‐ 3B / TaMPKK1 .2‐ 6B / TaMPK2 ‐ 1D / TaNAC2 ‐ 5B regulates low‐P stress response in Triticum aestivum
inferred← citeshttps://doi.org/10.1111/tpj.70986openalex-snapshot
Structure‐informed engineering of plant–microbe interactions
inferred← citeshttps://doi.org/10.1134/s1021443722060152openalex-snapshot
Genome-Wide Identification and Characterization of MYB-CC Gene Factor Family in Sorghum and Their Response to Phosphate Starvation
inferred← citeshttps://doi.org/10.1186/s12864-024-10630-6openalex-snapshot
Transcription factor binding specificities of the oomycete Phytophthora infestans reflect conserved and divergent evolutionary patterns and predict function
inferred← citeshttps://doi.org/10.1186/s12870-022-03867-4openalex-snapshot
Integrated analyses reveal the response of peanut to phosphorus deficiency on phenotype, transcriptome and metabolome
inferred← citeshttps://doi.org/10.1371/journal.ppat.1013601openalex-snapshot
Starve or share? Phosphate availability shapes plant–microbe interactions
inferred← citeshttps://doi.org/10.2210/pdb6kks/pdbopenalex-snapshot
Structural insights into target DNA recognition by R2R3-type MYB transcription factor
inferred← citeshttps://doi.org/10.3390/agriculture16181947openalex-snapshot
The Aspartate Kinase GmAK1 Controls Low-Phosphate Tolerance and Seed Oil Content in Soybean
inferred← citeshttps://doi.org/10.3390/biology15131050openalex-snapshot
An MYB-Related Transcription Factor, UpMYB-PHL, Is Involved in Salt Tolerance by Coordinating Phosphorus Transporter and Energy Metabolism in Ulva prolifera
inferred← citeshttps://doi.org/10.3390/genes10121018openalex-snapshot
Plant PHR Transcription Factors: Put on A Map
inferred← citeshttps://doi.org/10.3390/ijms22115662openalex-snapshot
Plant Transcription Factors Involved in Drought and Associated Stresses
inferred← citeshttps://doi.org/10.3390/plants12051011openalex-snapshot
Genome-Wide Analysis of MYB Transcription Factor Gene Superfamily Reveals BjPHL2a Involved in Modulating the Expression of BjCHI1 in Brassica juncea
inferred← citeshttps://doi.org/10.5010/jpb.2024.51.014.129openalex-snapshot
Phosphate depletion: research status and challenges in agriculture
inferred← citeshttps://doi.org/10.64898/2026.05.18.725930openalex-snapshot
Prediction of Transcription Factor DNA Binding Affinity with High-Throughput K d Measurements and Deep Learning
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