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Utility of PAX 8 mouse monoclonal antibody in the diagnosis of thyroid, thymic, pleural and lung tumours: a comparison with polyclonal PAX 8 antibody

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cncy.20136openalex-snapshot
PAX8 is expressed in pancreatic well‐differentiated neuroendocrine tumors and in extrapancreatic poorly differentiated neuroendocrine carcinomas in fine‐needle aspiration biopsy specimens
inferredcites →https://doi.org/10.1007/s00418-011-0866-3openalex-snapshot
Immunohistochemical assessment of Pax8 expression during pancreatic islet development and in human neuroendocrine tumors
inferredcites →https://doi.org/10.1038/296200a0openalex-snapshot
Molecular recognition and the future of monoclonal antibodies
inferredcites →https://doi.org/10.1038/labinvest.2008.168openalex-snapshot
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription
inferredcites →https://doi.org/10.1038/modpathol.2010.176openalex-snapshot
PAX8 expression reliably distinguishes pancreatic well-differentiated neuroendocrine tumors from ileal and pulmonary well-differentiated neuroendocrine tumors and pancreatic acinar cell carcinoma
inferredcites →https://doi.org/10.1038/modpathol.2011.162openalex-snapshot
N-terminal PAX8 polyclonal antibody shows cross-reactivity with N-terminal region of PAX5 and is responsible for reports of PAX8 positivity in malignant lymphomas
inferredcites →https://doi.org/10.1038/modpathol.2011.3openalex-snapshot
PAX 8 expression in non-neoplastic tissues, primary tumors, and metastatic tumors: a comprehensive immunohistochemical study
inferredcites →https://doi.org/10.1038/nrc1778openalex-snapshot
A PANorama of PAX genes in cancer and development
inferredcites →https://doi.org/10.1097/pai.0b013e318257cc1copenalex-snapshot
PAX8 Mouse Monoclonal Antibody [BC12] Recognizes a Restricted Epitope and Is Highly Sensitive in Renal Cell and Ovarian Cancers But Does Not Cross-react With B Cells and Tumors of Pancreatic Origin
inferredcites →https://doi.org/10.1097/pas.0b013e3181da7687openalex-snapshot
PAX8 Reliably Distinguishes Ovarian Serous Tumors From Malignant Mesothelioma
inferredcites →https://doi.org/10.1097/pas.0b013e3181dc5e8aopenalex-snapshot
PAX8 (+)/p63 (−) Immunostaining Pattern in Renal Collecting Duct Carcinoma (CDC)
inferredcites →https://doi.org/10.1097/pas.0b013e3181fcd707openalex-snapshot
Oct4 Expression in Immature Teratoma of the Ovary
inferredcites →https://doi.org/10.1097/pas.0b013e318216c112openalex-snapshot
A Comprehensive Analysis of PAX8 Expression in Human Epithelial Tumors
inferredcites →https://doi.org/10.1097/pas.0b013e3182260735openalex-snapshot
Pax8 Expression in Thymic Epithelial Neoplasms
inferredcites →https://doi.org/10.1111/his.12020openalex-snapshot
PAX8 and PAX5 are differentially expressed in B‐cell and T‐cell lymphomas
inferredcites →https://doi.org/10.1309/8j2pqhf603whvl8kopenalex-snapshot
PAX-5 Expression in Pulmonary Neuroendocrine Neoplasms
inferredcites →https://doi.org/10.1309/ajcpzpqn0lugkmmeopenalex-snapshot
PAX5 Expression in Nonhematopoietic Tissues
inferredcites →https://doi.org/10.5858/2009-0664-oar1.1openalex-snapshot
Expression Patterns of PAX5, c-Met, and Paxillin in Neuroendocrine Tumors of the Lung

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4519866openalex-extracted
inferred← citeshttps://doi.org/10.1002/cncy.22634openalex-snapshot
The new endocrine WHO classification: What does this mean for thyroid cytology?
inferred← citeshttps://doi.org/10.1002/dc.25170openalex-snapshot
Case report: Primary adenocarcinoma NOS of the thymus and cytological features
inferred← citeshttps://doi.org/10.1002/jso.24393openalex-snapshot
Immunophenotypic and prognostic analysis of PAX8 and TTF‐1 expressions in neuroendocrine carcinomas of thymic origin: A comparative study with their pulmonary counterparts
inferred← citeshttps://doi.org/10.1007/978-1-4939-2339-7_9openalex-snapshot
Ancillary Studies: Contribution to Error and Error Prevention
inferred← citeshttps://doi.org/10.1007/978-3-030-73359-9_6openalex-snapshot
PAX8, an Emerging Player in Ovarian Cancer
inferred← citeshttps://doi.org/10.1007/978-3-030-80962-1_129-1openalex-snapshot
Immunohistochemistry in the Diagnosis of Primary and Secondary Cancers
inferred← citeshttps://doi.org/10.1007/978-3-031-89250-9_5openalex-snapshot
Mesothelioma
inferred← citeshttps://doi.org/10.1007/978-3-032-00763-6_129openalex-snapshot
Immunohistochemistry in the Diagnosis of Primary and Secondary Cancers
inferred← citeshttps://doi.org/10.1007/978-3-319-48379-5_4openalex-snapshot
Cytologic Features of Mediastinal Lesions
inferred← citeshttps://doi.org/10.1007/978-3-319-97508-5_5openalex-snapshot
Immunostains: Antibody Index – Solid Tumors
inferred← citeshttps://doi.org/10.1007/978-981-15-3164-4_9openalex-snapshot
Pathology of Thymic Carcinoma
inferred← citeshttps://doi.org/10.1007/s00292-018-0518-7openalex-snapshot
Transkriptionsfaktoren in der Tumordiagnostik
inferred← citeshttps://doi.org/10.1007/s00428-022-03437-xopenalex-snapshot
Insulinoma-associated-1 (INSM1) expression in thymic squamous cell carcinoma
inferred← citeshttps://doi.org/10.1007/s00428-024-03872-yopenalex-snapshot
PAX8 expression in cancerous and non-neoplastic tissue: a tissue microarray study on more than 17,000 tumors from 149 different tumor entities
inferred← citeshttps://doi.org/10.1007/s11033-025-10704-yopenalex-snapshot
The potential role of PAX5 and PAX8 in regulating telomerase activity: a narrative mini-review
inferred← citeshttps://doi.org/10.1007/s12022-018-9532-9openalex-snapshot
Immunohistochemical Biomarkers in Thyroid Pathology
inferred← citeshttps://doi.org/10.1007/s12022-023-09752-6openalex-snapshot
High-Grade Non-Anaplastic Thyroid Carcinomas of Follicular Cell Origin: A Review of Poorly Differentiated and High-Grade Differentiated Carcinomas
inferred← citeshttps://doi.org/10.1007/s12105-022-01509-7openalex-snapshot
Metastatic Disease to a Concurrent Thyroid Neoplasm: A Case Series and Review of the Literature
inferred← citeshttps://doi.org/10.1007/s12105-026-01901-7openalex-snapshot
Proceedings of the 2026 North American Society of Head and Neck Pathology Companion Meeting, San Antonio, TX, March 22, 2026: It’s a Trap! Pitfalls in Thyroid Pathology: Mets or Not Mets?
inferred← citeshttps://doi.org/10.1016/j.anndiagpath.2021.151762openalex-snapshot
Polyclonal PAX8 expression in carcinomas of the biliary tract — Frequent non-specific staining represents a potential diagnostic pitfall
inferred← citeshttps://doi.org/10.1016/j.anndiagpath.2023.152248openalex-snapshot
The over diagnosis of diffuse mesothelioma: An analysis of 311 cases with recommendations for the avoidance of pitfalls
inferred← citeshttps://doi.org/10.1016/j.ctarc.2025.101045openalex-snapshot
Immunohistochemical analysis of thyroid transcription factor-1 in type A and AB thymomas comparing multiple primary antibody clones
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e28251openalex-snapshot
Prognostic value of PAX8 in small cell lung cancer
inferred← citeshttps://doi.org/10.1016/j.humpath.2022.04.007openalex-snapshot
Unusual staining of immunohistochemical markers PAX8 and CDX2 in breast carcinoma: a potential diagnostic pitfall
inferred← citeshttps://doi.org/10.1016/j.humpath.2023.09.007openalex-snapshot
PAX1 expression in thymic epithelial neoplasms and morphologic mimics
inferred← citeshttps://doi.org/10.1016/j.humpath.2024.105695openalex-snapshot
PAX6 is a useful marker for pancreatic origin of neuroendocrine neoplasms: A tissue microarray study evaluating more than 19,000 tumors from 150 different tumor types
inferred← citeshttps://doi.org/10.1016/j.humpath.2026.106198openalex-snapshot
Practical approaches to the diagnosis and differential diagnosis of T-lymphoblastic leukemia/lymphoma
inferred← citeshttps://doi.org/10.1016/j.ijscr.2024.109762openalex-snapshot
Intra thyroid thymic carcinoma: A case report and literature review
inferred← citeshttps://doi.org/10.1016/j.jtho.2018.12.005openalex-snapshot
Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer
inferred← citeshttps://doi.org/10.1016/j.jtho.2026.103611openalex-snapshot
Challenges and Controversies in the Diagnosis and Management of Thymic Epithelial Tumors from the Thymic Tumor Subcommittee of the International Association for the Study of Lung Cancer Rare Tumors Committee
inferred← citeshttps://doi.org/10.1016/j.modpat.2025.100903openalex-snapshot
A Rational Approach to the Diagnosis of Liver Metastases
inferred← citeshttps://doi.org/10.1016/j.pathol.2017.09.005openalex-snapshot
Emerging entities in renal cell neoplasia: thyroid-like follicular renal cell carcinoma and multifocal oncocytoma-like tumours associated with oncocytosis
inferred← citeshttps://doi.org/10.1038/s41379-021-00839-1openalex-snapshot
Expression patterns for Bcl-2, EMA, β-catenin, E-cadherin, PAX8, and MIB1 in thymomas
inferred← citeshttps://doi.org/10.1053/j.semdp.2017.11.012openalex-snapshot
Immunohistochemistry, carcinomas of unknown primary, and incidence rates
inferred← citeshttps://doi.org/10.1089/thy.2020.0944openalex-snapshot
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer
inferred← citeshttps://doi.org/10.1097/pai.0000000000000549openalex-snapshot
Does Strong and Diffuse PAX-8 Positivity Occur in Primary Lung Carcinoma? An Immunohistochemical Study of 418 Cases and Review of the Literature
inferred← citeshttps://doi.org/10.1097/pai.0000000000000760openalex-snapshot
Estrogen Receptor-α Quantification in Breast Cancer: Concordance Between Immunohistochemical Assays and mRNA-In Situ Hybridization for ESR1 Gene
inferred← citeshttps://doi.org/10.1097/pap.0000000000000069openalex-snapshot
Metastatic Carcinoma of Unknown Primary
inferred← citeshttps://doi.org/10.1097/pap.0000000000000256openalex-snapshot
An Algorithmic Immunohistochemical Approach to Define Tumor Type and Assign Site of Origin
inferred← citeshttps://doi.org/10.1097/pap.0000000000000380openalex-snapshot
Advances in Thyroid Pathology: High Grade Follicular Cell-derived Thyroid Carcinoma and Anaplastic Thyroid Carcinoma
inferred← citeshttps://doi.org/10.1097/pas.0000000000002305openalex-snapshot
A Confirmed Extrarenal Birt-Hogg-Dubé-Associated Oncocytic Neoplasm
inferred← citeshttps://doi.org/10.1111/his.14246openalex-snapshot
Metastasis to the thyroid gland: a single‐institution 16‐year experience
inferred← citeshttps://doi.org/10.1111/pin.12783openalex-snapshot
Renal medullary carcinoma in a young mixed‐race man in Japan
inferred← citeshttps://doi.org/10.1136/jcp-2023-209070openalex-snapshot
PAX5 and CD70 are expressed in thymic carcinoma but not in atypical thymoma (WHO type B3 thymoma): an immunohistochemical analysis of 60 cases
inferred← citeshttps://doi.org/10.1159/000363142openalex-snapshot
VEGF mRNA Assessment in Human Pterygium: A New ‘Scope' for a Future Hope
inferred← citeshttps://doi.org/10.1507/endocrj.ej18-0282openalex-snapshot
Utility of monoclonal PAX8 antibody for distinguishing intrathyroid thymic carcinoma from follicular cell-derived thyroid carcinoma
inferred← citeshttps://doi.org/10.21037/med-22-54openalex-snapshot
Diagnostic approach to prevascular (anterior) mediastinal lymphomas: when thoracic pathology meets hematopathology
inferred← citeshttps://doi.org/10.2174/0109298673339877250210105022openalex-snapshot
Dermal Melanocytes Detectability for Distinguishing In Situ and Early Invasive Melanoma: A Narrative Review
inferred← citeshttps://doi.org/10.3389/fonc.2023.1266485openalex-snapshot
Pulmonary metastasis of stage I, low-grade endometrioid carcinoma: two case reports and the literature review
inferred← citeshttps://doi.org/10.3389/fonc.2025.1468233openalex-snapshot
BRAF V600E-mutated lung adenocarcinoma with thyroid metastasis as the initial manifestation: a case report
inferred← citeshttps://doi.org/10.3390/cancers14082013openalex-snapshot
Diagnostic Challenges in the Cytology of Thymic Epithelial Neoplasms
inferred← citeshttps://doi.org/10.4018/978-1-5225-5876-7.ch002openalex-snapshot
Digital Image Analysis in Clinical and Experimental Pathology
inferred← citeshttps://doi.org/10.4132/jptm.2020.06.08openalex-snapshot
Analysis of PAX8 immunohistochemistry in lung cancers: a meta-analysis
inferred← citeshttps://doi.org/10.55418/9781933477176-2openalex-snapshot
Renal Tumors of Adults
inferred← citeshttps://doi.org/10.55418/9781933477633-16openalex-snapshot
Secondary Tumors of the Thyroid Gland
inferred← citeshttps://doi.org/10.5858/arpa.2016-0119-raopenalex-snapshot
Diagnostic Immunohistochemistry: What Can Go Wrong and How to Prevent It
inferred← citeshttps://doi.org/10.5858/arpa.2022-0483-raopenalex-snapshot
Utility of Immunohistochemistry in the Diagnosis of Pleuropulmonary and Mediastinal Cancers: A Review and Update
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