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CIC – DUX 4 fusion‐positive round‐cell sarcomas of soft tissue and bone: a single‐institution morphological and molecular analysis of seven cases
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cncr.22456openalex-snapshot
Adjuvant and neoadjuvant chemotherapy for Ewing sarcoma family tumors in patients aged between 40 and 60
inferredcites →https://doi.org/10.1002/gcc.20945openalex-snapshot
High prevalence of CIC fusion with double‐homeobox (DUX4) transcription factors in EWSR1 ‐negative undifferentiated small blue round cell sarcomas
inferredcites →https://doi.org/10.1002/gcc.22172openalex-snapshot
Distinct transcriptional signature and immunoprofile of CIC‐DUX4 fusion–positive round cell tumors compared to EWSR1 ‐rearranged ewing sarcomas: Further evidence toward distinct pathologic entities
inferredcites →https://doi.org/10.1007/s00401-014-1312-0openalex-snapshot
Unusual primary cerebral localization of a CIC–DUX4 translocation tumor of the Ewing sarcoma family
inferredcites →https://doi.org/10.1007/s00428-013-1499-9openalex-snapshot
Superficial EWSR1-negative undifferentiated small round cell sarcoma with CIC/DUX4 gene fusion: a new variant of Ewing-like tumors with locoregional lymph node metastasis
inferredcites →https://doi.org/10.1016/0165-4608(92)90005-sopenalex-snapshot
12q13 abnormality in rhabdomyosarcoma
inferredcites →https://doi.org/10.1016/0165-4608(95)00240-5openalex-snapshot
t(4;19)(q35;q13.1): A recurrent change in primitive mesenchymal tumors?
inferredcites →https://doi.org/10.1016/j.biocel.2014.04.022openalex-snapshot
Round cell sarcomas – Biologically important refinements in subclassification
inferredcites →https://doi.org/10.1016/j.cancergencyto.2009.06.011openalex-snapshot
Fusion of EWSR1 with the DUX4 facioscapulohumeral muscular dystrophy region resulting from t(4;22)(q35;q12) in a case of embryonal rhabdomyosarcoma
inferredcites →https://doi.org/10.1016/j.cancergencyto.2009.06.015openalex-snapshot
Detailed cytogenetic and array analysis of pediatric primitive sarcomas reveals a recurrent CIC–DUX4 fusion gene event
inferredcites →https://doi.org/10.1016/j.cancergencyto.2010.04.012openalex-snapshot
Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor
inferredcites →https://doi.org/10.1016/j.humpath.2009.04.013openalex-snapshot
Undifferentiated sarcoma: does it exist? A clinicopathologic study of 7 pediatric cases and review of literature
inferredcites →https://doi.org/10.1016/j.humpath.2011.04.023openalex-snapshot
The CIC-DUX4 fusion transcript is present in a subgroup of pediatric primitive round cell sarcomas
inferredcites →https://doi.org/10.1038/modpathol.2014.83openalex-snapshot
CIC-DUX sarcomas demonstrate frequent MYC amplification and ETS-family transcription factor expression
inferredcites →https://doi.org/10.1093/annonc/mds117openalex-snapshot
Primary metastatic Ewing's family tumors: results of the Italian Sarcoma Group and Scandinavian Sarcoma Group ISG/SSG IV Study including myeloablative chemotherapy and total-lung irradiation
inferredcites →https://doi.org/10.1093/hmg/ddl136openalex-snapshot
Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation
inferredcites →https://doi.org/10.1097/pap.0000000000000036openalex-snapshot
Round Cell Tumors of Bone
inferredcites →https://doi.org/10.1097/pas.0000000000000286openalex-snapshot
A Novel CIC-FOXO4 Gene Fusion in Undifferentiated Small Round Cell Sarcoma
inferredcites →https://doi.org/10.1097/pas.0b013e318297a57dopenalex-snapshot
Undifferentiated Small Round Cell Sarcoma With t(4;19)(q35;q13.1) CIC-DUX4 Fusion
inferredcites →https://doi.org/10.1111/cyt.12079openalex-snapshot
CD 99‐positive undifferentiated round cell sarcoma diagnosed on fine needle aspiration cytology, later found to harbour a CIC ‐ DUX 4 translocation: a recently described entity
inferredcites →https://doi.org/10.1111/his.12281openalex-snapshot
Round cell sarcomas beyond E wing: emerging entities
inferredcites →https://doi.org/10.1200/jco.1993.11.9.1763openalex-snapshot
Prognostic significance of histopathologic response to chemotherapy in nonmetastatic Ewing's sarcoma of the extremities.
inferredcites →https://doi.org/10.12659/ajcr.892551openalex-snapshot
High-Grade Undifferentiated Small Round Cell Sarcoma with t(4;19)(q35;q13.1) CIC-DUX4 Fusion: Emerging Entities of Soft Tissue Tumors with Unique Histopathologic Features – A Case Report and Literature Review
inferredcites →https://doi.org/10.1371/journal.pone.0099439openalex-snapshot
The “Grep” Command But Not FusionMap, FusionFinder or ChimeraScan Captures the CIC-DUX4 Fusion Gene from Whole Transcriptome Sequencing Data on a Small Round Cell Tumor with t(4;19)(q35;q13)
inferredcites →https://doi.org/10.2350/07-06-0296.1openalex-snapshot
Translocation (4;19)(q35;q13.1)–Associated Primitive round Cell Sarcoma: Report of a Case and Review of the Literature
inferredcites →https://doi.org/10.2353/jmoldx.2007.070053openalex-snapshot
Undifferentiated Small Round Cell Sarcomas with Rare EWS Gene Fusions
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4197931openalex-extracted
A Global CollaboRAtive Study of CIC-Rearranged, BCOR::CCNB3-Rearranged and Other Ultra-Rare Unclassified Undifferentiated Round Cell Sarcomas (GRACefUl)
inferred← citeshttps://doi.org/10.1002/cam4.4688openalex-snapshot
Comorbidities rather than older age define outcome in adult patients with tumors of the Ewing sarcoma family
inferred← citeshttps://doi.org/10.1002/cam4.5539openalex-snapshot
Patterns of care and outcome of CIC‐rearranged sarcoma patients: A nationwide study of the French sarcoma group
inferred← citeshttps://doi.org/10.1002/cam4.6113openalex-snapshot
Clinical characteristics and outcomes for children, adolescents and young adults with “CIC‐fused” or “BCOR‐rearranged” soft tissue sarcomas: A multi‐institutional European retrospective analysis
inferred← citeshttps://doi.org/10.1002/cam4.71495openalex-snapshot
A Real‐World Analysis of Outcomes in CIC‐Rearranged Sarcomas: A Canadian Sarcoma Research and Clinical Collaboration (CanSaRCC) Study
inferred← citeshttps://doi.org/10.1002/cjp2.64openalex-snapshot
Fluorescence in situ hybridization in surgical pathology: principles and applications
inferred← citeshttps://doi.org/10.1002/dc.23520openalex-snapshot
A case report of CIC ‐rearranged undifferentiated small round cell sarcoma in the cerebrum
inferred← citeshttps://doi.org/10.1002/gcc.22454openalex-snapshot
ETV transcriptional upregulation is more reliable than RNA sequencing algorithms and FISH in diagnosing round cell sarcomas with CIC gene rearrangements
inferred← citeshttps://doi.org/10.1002/jcp.27558openalex-snapshot
Ewing‐like sarcoma: An emerging family of round cell sarcomas
inferred← citeshttps://doi.org/10.1002/ped4.12264openalex-snapshot
Primary cardiac CIC‐rearranged undifferentiated sarcoma in an infant
inferred← citeshttps://doi.org/10.1007/978-3-030-29676-6_39openalex-snapshot
Small Blue Round Cell Tumors
inferred← citeshttps://doi.org/10.1007/978-981-96-4872-6_12openalex-snapshot
Pathological Aspects and Recent Advances in Pathology
inferred← citeshttps://doi.org/10.1007/s00428-019-02678-7openalex-snapshot
Update on selected advances in the immunohistochemical and molecular genetic analysis of soft tissue tumors
inferred← citeshttps://doi.org/10.1007/s00428-019-02720-8openalex-snapshot
Ewing sarcoma and Ewing-like tumors
inferred← citeshttps://doi.org/10.1007/s10014-020-00366-yopenalex-snapshot
Primary spinal intramedullary Ewing-like sarcoma harboring CIC-DUX4 translocation: a similar cytological appearance as its soft tissue counterpart but no lobulation in association with desmoplastic stroma
inferred← citeshttps://doi.org/10.1007/s12672-025-01941-5openalex-snapshot
Primary capicua transcriptional repressor-rearranged sarcoma in the thyroid gland with cervical lymph node and lung metastases: a case report and literature review
inferred← citeshttps://doi.org/10.1016/b978-0-323-54806-9.50069-0openalex-snapshot
Undifferentiated Round Cell Tumor With CIC-DUX4 Translocation
inferred← citeshttps://doi.org/10.1016/j.adro.2023.101352openalex-snapshot
Methylation and Molecular Profiling to Aid in Diagnosis and Radiation Treatment for an Intracranial Ewing Sarcoma in a Pediatric Patient: A Case Report
inferred← citeshttps://doi.org/10.1016/j.anndiagpath.2021.151800openalex-snapshot
Novel fusion sarcomas including targetable NTRK and ALK
inferred← citeshttps://doi.org/10.1016/j.anndiagpath.2023.152153openalex-snapshot
Clinicopathological features of five cases of CIC::DUX4 positive sarcomas, including literature review
inferred← citeshttps://doi.org/10.1016/j.anndiagpath.2024.152320openalex-snapshot
Differential cyclin-E1 expression in CIC-rearranged sarcoma
inferred← citeshttps://doi.org/10.1016/j.annpat.2022.01.017openalex-snapshot
Les sarcomes osseux monotones à cellules rondes/fusiformes avec translocations (hors Ewing)
inferred← citeshttps://doi.org/10.1016/j.annpat.2024.09.012openalex-snapshot
Sarcomes indifférenciés à cellules rondes dans la 5e édition de la classification OMS (2020)
inferred← citeshttps://doi.org/10.1016/j.ejca.2023.01.003openalex-snapshot
A global collaboRAtive study of CIC-rearranged, BCOR::CCNB3-rearranged and other ultra-rare unclassified undifferentiated small round cell sarcomas (GRACefUl)
inferred← citeshttps://doi.org/10.1016/j.humpath.2017.01.012openalex-snapshot
NUTM2A-CIC fusion small round cell sarcoma: a genetically distinct variant of CIC-rearranged sarcoma
inferred← citeshttps://doi.org/10.1016/j.humpath.2017.02.032openalex-snapshot
Diagnostic utility of cyclin D1 in the diagnosis of small round blue cell tumors in children and adolescents: beware of cyclin D1 expression in clear cell sarcoma of the kidney and CIC-DUX4 fusion–positive sarcomas. Comment on Magro et al (2016)
inferred← citeshttps://doi.org/10.1016/j.humpath.2018.12.006openalex-snapshot
New fusion sarcomas: histopathology and clinical significance of selected entities
inferred← citeshttps://doi.org/10.1016/j.jmoldx.2017.09.007openalex-snapshot
Development and Evaluation of a Pan-Sarcoma Fusion Gene Detection Assay Using the NanoString nCounter Platform
inferred← citeshttps://doi.org/10.1016/j.mpdhp.2017.08.003openalex-snapshot
Molecular testing of sarcomas
inferred← citeshttps://doi.org/10.1016/j.mpdhp.2022.09.003openalex-snapshot
Small round blue cell sarcomas of bone: an update on classification, pathology and molecular profiling
inferred← citeshttps://doi.org/10.1016/j.path.2019.03.007openalex-snapshot
Bone Pathology for Hematopathologists
inferred← citeshttps://doi.org/10.1016/j.path.2023.07.001openalex-snapshot
Sarcomas with EWSR1::Non-ETS Fusion (EWSR1::NFATC2 and EWSR1::PATZ1)
inferred← citeshttps://doi.org/10.1016/j.pathol.2017.11.092openalex-snapshot
CIC-rearranged sarcoma of the pleura: an unreported primary site, expanding the anatomical distribution of an emerging entity
inferred← citeshttps://doi.org/10.1016/j.prp.2017.06.008openalex-snapshot
Primary undifferentiated small round cell sarcoma of the deep abdominal wall with a novel variant of t(10;19) CIC-DUX4 gene fusion
inferred← citeshttps://doi.org/10.1016/j.prp.2022.153773openalex-snapshot
CIC rearranged sarcomas: A single institution experience of the potential pitfalls in interpreting CIC FISH results
inferred← citeshttps://doi.org/10.1016/j.prp.2024.155406openalex-snapshot
Pathogenetic and molecular classifications of soft tissue and bone tumors: A 2024 update
inferred← citeshttps://doi.org/10.1038/modpathol.2016.140openalex-snapshot
Evaluation of ETV4 and WT1 expression in CIC-rearranged sarcomas and histologic mimics
inferred← citeshttps://doi.org/10.1038/s41389-021-00357-4openalex-snapshot
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma
inferred← citeshttps://doi.org/10.1038/s41598-019-52143-3openalex-snapshot
Establishment of a novel human CIC-DUX4 sarcoma cell line, Kitra-SRS, with autocrine IGF-1R activation and metastatic potential to the lungs
inferred← citeshttps://doi.org/10.1053/j.semdp.2021.10.002openalex-snapshot
From the ashes of “Ewing-like” sarcoma: A contemporary update of the classification, immunohistochemistry, and molecular genetics of round cell sarcomas
inferred← citeshttps://doi.org/10.1080/01913123.2020.1737610openalex-snapshot
Ultrastructure of CIC-DUX4 sarcoma: the first pathological report
inferred← citeshttps://doi.org/10.1080/14737140.2020.1753509openalex-snapshot
Evolution in the management of soft tissue sarcoma: classification, surgery and use of radiotherapy
inferred← citeshttps://doi.org/10.1097/pap.0000000000000284openalex-snapshot
The 2020 WHO Classification of Tumors of Soft Tissue: Selected Changes and New Entities
inferred← citeshttps://doi.org/10.1097/pap.0000000000000532openalex-snapshot
Small Round Cell Tumors of Soft Tissue and Skeleton in Children and Youth: A Narrative and TruSight-Based Illustrative Review of Diagnostic Cases
inferred← citeshttps://doi.org/10.1097/pas.0000000000000772openalex-snapshot
DUX4 Immunohistochemistry Is a Highly Sensitive and Specific Marker for CIC-DUX4 Fusion-positive Round Cell Tumor
inferred← citeshttps://doi.org/10.1097/pas.0000000000000846openalex-snapshot
Sarcomas With CIC-rearrangements Are a Distinct Pathologic Entity With Aggressive Outcome
inferred← citeshttps://doi.org/10.1097/pas.0000000000001098openalex-snapshot
Clinicopathologic Features of a Series of Primary Renal CIC-rearranged Sarcomas With Comprehensive Molecular Analysis
inferred← citeshttps://doi.org/10.1097/pas.0000000000001487openalex-snapshot
Primary Vascular Tumors of Bone
inferred← citeshttps://doi.org/10.1111/cas.13413openalex-snapshot
A double‐edged sword: The world according to Capicua in cancer
inferred← citeshttps://doi.org/10.1111/cup.14748openalex-snapshot
CIC ‐ DUX4 Sarcoma of the Skin: A Rare Case Report and Literature Review
inferred← citeshttps://doi.org/10.1111/cup.14781openalex-snapshot
Dermal CIC ‐Rearranged Sarcoma With Neuroendocrine Differentiation Mimicking Merkel Cell Carcinoma
inferred← citeshttps://doi.org/10.1111/cup.14792openalex-snapshot
Ancillary Tools for the Diagnosis of CIC ‐Rearranged Sarcoma: A Comprehensive Review
inferred← citeshttps://doi.org/10.1111/cup.70085openalex-snapshot
Superficial CIC::DUX4 Sarcoma With Focal WT1 Expression: Histomorphologic Clues and Immunohistochemical Pitfalls
inferred← citeshttps://doi.org/10.1111/his.13252openalex-snapshot
CIC break‐apart fluorescence in‐situ hybridization misses a subset of CIC – DUX 4 sarcomas: a clinicopathological and molecular study
inferred← citeshttps://doi.org/10.1111/his.15016openalex-snapshot
Fusion transcriptome profiling defines the monoclonal origin of multifocal epithelioid haemangioma of bone
inferred← citeshttps://doi.org/10.1111/pin.13293openalex-snapshot
Ewing and Ewing‐like sarcomas: A morphological guide through genetically‐defined entities
inferred← citeshttps://doi.org/10.1136/jclinpath-2016-204247openalex-snapshot
Novel exon–exon breakpoint in CIC-DUX4 fusion sarcoma identified by anchored multiplex PCR (Archer FusionPlex Sarcoma Panel)
inferred← citeshttps://doi.org/10.1155/2020/3498549openalex-snapshot
Survey of Paediatric Oncologists and Pathologists regarding Their Views and Experiences with Variant Translocations in Ewing and Ewing-Like Sarcoma: A Report of the Children’s Oncology Group
inferred← citeshttps://doi.org/10.1158/0008-5472.can-16-3351openalex-snapshot
CIC-DUX4 Induces Small Round Cell Sarcomas Distinct from Ewing Sarcoma
inferred← citeshttps://doi.org/10.1158/0008-5472.can-21-1222openalex-snapshot
Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma
inferred← citeshttps://doi.org/10.1158/2767-9764.crc-24-0348openalex-snapshot
The Capicua C1 Domain Is Required for Full Activity of the CIC::DUX4 Fusion Oncoprotein
inferred← citeshttps://doi.org/10.1177/1093526617698263openalex-snapshot
BCOR-CCNB3 Undifferentiated Sarcoma—Does Immunohistochemistry Help in the Identification?
inferred← citeshttps://doi.org/10.1177/1093526617706818openalex-snapshot
Sarcoma With CIC-DUX4 Gene Fusion
inferred← citeshttps://doi.org/10.1177/1093526617707856openalex-snapshot
Primary Spinal Epidural CIC-DUX4 Undifferentiated Sarcoma in a Child
inferred← citeshttps://doi.org/10.1186/s12876-020-01266-3openalex-snapshot
Pancreaticoduodenectomy for a primary duodenal capicua transcriptional repressor (CIC) -rearranged sarcoma with severe bleeding: a case report
inferred← citeshttps://doi.org/10.1186/s12943-025-02485-6openalex-snapshot
Modeling CIC::DUX4 sarcoma reveals oncogene-mediated MHCI-dependent immune evasion
inferred← citeshttps://doi.org/10.12659/ajcr.925683openalex-snapshot
A Rare Case of Round Cell Sarcoma with CIC-DUX4 Mutation Mimicking a Phlegmon: Review of Literature
inferred← citeshttps://doi.org/10.17116/patol20238501143openalex-snapshot
Changes in the WHO classification (2020) of soft tissue tumors
inferred← citeshttps://doi.org/10.17116/patol20238503164openalex-snapshot
CIC-rearranged sarcoma: a case report and literature review
inferred← citeshttps://doi.org/10.17116/patol20238505113openalex-snapshot
Clinical and morphological characteristics of Ewing’s sarcoma and the algorithm for diagnosing undifferentiated round cell sarcomas
inferred← citeshttps://doi.org/10.21873/invivo.13054openalex-snapshot
Chromosome Translocation t(10;19)(q26;q13) in a CIC-sarcoma
inferred← citeshttps://doi.org/10.2217/fon-2018-0075openalex-snapshot
The Key Role of Pathology, Surgery and Radiotherapy in the Initial Management of Soft Tissue Sarcoma
inferred← citeshttps://doi.org/10.32074/1591-951x-213openalex-snapshot
The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives
inferred← citeshttps://doi.org/10.3389/fmed.2025.1613510openalex-snapshot
Primary ovarian CIC-rearranged sarcoma in a child: a rare case report and review of the literature
inferred← citeshttps://doi.org/10.3389/fonc.2022.1018992openalex-snapshot
A case report of CIC–DUX4 fusion-positive sarcoma in the pelvic cavity with targeted next-generation sequencing results
inferred← citeshttps://doi.org/10.3389/fonc.2023.1095219openalex-snapshot
Targeting cyclin-dependent kinases in sarcoma treatment: Current perspectives and future directions
inferred← citeshttps://doi.org/10.3389/fonc.2026.1752091openalex-snapshot
Clinicopathologic correlates of Ewing (FET::ETS-rearranged) sarcoma and non-Ewing undifferentiated small round cell sarcomas across skeletal and extraskeletal sites
inferred← citeshttps://doi.org/10.3390/cancers12113092openalex-snapshot
Rare Primary Malignant Bone Sarcomas
inferred← citeshttps://doi.org/10.3390/cancers14215411openalex-snapshot
CIC-Rearranged Sarcomas: An Intriguing Entity That May Lead the Way to the Comprehension of More Common Cancers
inferred← citeshttps://doi.org/10.3390/cancers16132314openalex-snapshot
The Impact of Expert Pathology Review and Molecular Diagnostics on the Management of Sarcoma Patients: A Prospective Study of the Hellenic Group of Sarcomas and Rare Cancers
inferred← citeshttps://doi.org/10.3390/cancers18010133openalex-snapshot
Age-Related Clinicopathologic Patterns in Ewing Sarcoma (FET::ETS Family): A Comparative Analysis of Pediatric and Adult Patients
inferred← citeshttps://doi.org/10.3390/ijms21051818openalex-snapshot
DNA Methylation Profiling for Diagnosing Undifferentiated Sarcoma with Capicua Transcriptional Receptor (CIC) Alterations
inferred← citeshttps://doi.org/10.3390/jcm10081685openalex-snapshot
Ewing Sarcoma—Diagnosis, Treatment, Clinical Challenges and Future Perspectives
inferred← citeshttps://doi.org/10.51847/dedmr1fe39openalex-snapshot
A CIC::DUX4 Sarcoma Model Reveals Oncogene-Driven MHCI-Dependent Immune Evasion
inferred← citeshttps://doi.org/10.55418/9781933477138-11openalex-snapshot
Poorly/Undifferentiated Small Round/Spindle Cell Sarcoma
inferred← citeshttps://doi.org/10.7759/cureus.85154openalex-snapshot
CIC::DUX4 Sarcoma With Preferentially Expressed Antigen in Melanoma (PRAME) Immunopositivity
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