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Decrease of intracellular ROS by arbutin is associated with apoptosis induction and downregulation of IL‐1β and TNF‐α in LNCaP; prostate cancer
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/jcb.24897openalex-snapshot
IL‐1β Induces p62/SQSTM1 and Represses Androgen Receptor Expression in Prostate Cancer Cells
inferredcites →https://doi.org/10.1007/978-94-010-0163-2_1openalex-snapshot
Activators and Target Genes of Rel/NF-кB Transcription Factors
inferredcites →https://doi.org/10.1007/s00011-012-0474-2openalex-snapshot
Anti-inflammatory effects of arbutin in lipopolysaccharide-stimulated BV2 microglial cells
inferredcites →https://doi.org/10.1007/s10495-009-0416-9openalex-snapshot
Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer
inferredcites →https://doi.org/10.1007/s10495-014-1032-xopenalex-snapshot
Arbutin, an intracellular hydroxyl radical scavenger, protects radiation-induced apoptosis in human lymphoma U937 cells
inferredcites →https://doi.org/10.1016/0022-1759(83)90303-4openalex-snapshot
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
inferredcites →https://doi.org/10.1016/j.bbapap.2008.09.023openalex-snapshot
Proteomics analysis of A375 human malignant melanoma cells in response to arbutin treatment
inferredcites →https://doi.org/10.1016/j.bcp.2006.04.011openalex-snapshot
NF-κB activation by reactive oxygen species: Fifteen years later
inferredcites →https://doi.org/10.1016/j.cyto.2018.01.003openalex-snapshot
Association of TNF-α but not IL-1β levels with the presence of Helicobacter pylori infection increased the risk of peptic ulcer development
inferredcites →https://doi.org/10.1016/j.foodchem.2010.12.069openalex-snapshot
Pyrus biossieriana Buhse leaf extract: An antioxidant, antihyperglycaemic and antihyperlipidemic agent
inferredcites →https://doi.org/10.1016/j.ijporl.2012.01.041openalex-snapshot
Effect of caffeic acid phenethyl ester (CAPE) on H2O2 induced oxidative and inflammatory responses in human middle ear epithelial cells
inferredcites →https://doi.org/10.1016/j.intimp.2011.12.009openalex-snapshot
Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): Anti-inflammatory and anti-cancer properties
inferredcites →https://doi.org/10.1016/j.molcel.2012.09.025openalex-snapshot
Physiological Roles of Mitochondrial Reactive Oxygen Species
inferredcites →https://doi.org/10.1016/s0076-6879(02)52007-3openalex-snapshot
[5] Detection of intracellular reactive oxygen species in cultured cells using fluorescent probes
inferredcites →https://doi.org/10.1038/nature09663openalex-snapshot
A role for mitochondria in NLRP3 inflammasome activation
inferredcites →https://doi.org/10.1038/s41598-017-05416-8openalex-snapshot
Deoxyarbutin displays antitumour activity against melanoma in vitro and in vivo through a p38-mediated mitochondria associated apoptotic pathway
inferredcites →https://doi.org/10.1038/sj.onc.1203239openalex-snapshot
Activators and target genes of Rel/NF-κB transcription factors
inferredcites →https://doi.org/10.1038/srep34520openalex-snapshot
Tea polyphenols inhibit the activation of NF-κB and the secretion of cytokines and matrix metalloproteinases by macrophages stimulated with Fusobacterium nucleatum
inferredcites →https://doi.org/10.1084/jem.20110367openalex-snapshot
Mitochondrial reactive oxygen species drive proinflammatory cytokine production
inferredcites →https://doi.org/10.1093/nar/29.9.e45openalex-snapshot
A new mathematical model for relative quantification in real-time RT-PCR
inferredcites →https://doi.org/10.1097/cej.0b013e32834a8002openalex-snapshot
The role of oxidative stress in prostate cancer
inferredcites →https://doi.org/10.1111/j.1751-1097.1995.tb02369.xopenalex-snapshot
ACTIVATION OF NF‐KB IN HUMAN SKIN FIBROBLASTS BY THE OXIDATIVE STRESS GENERATED BY UVA RADIATION
inferredcites →https://doi.org/10.1158/0008-5472.can-12-3970openalex-snapshot
Interleukin-1β Promotes Skeletal Colonization and Progression of Metastatic Prostate Cancer Cells with Neuroendocrine Features
inferredcites →https://doi.org/10.1159/000347136openalex-snapshot
Immunotherapy with a Recombinant Hybrid Molecule Alleviates Allergic Responses More Efficiently than an Allergenic Cocktail or Pollen Extract in a Model of Chenopodium album Allergy
inferredcites →https://doi.org/10.1177/1177271918755391openalex-snapshot
Reactive Oxygen Species: A Key Constituent in Cancer Survival
inferredcites →https://doi.org/10.1177/1534735416681639openalex-snapshot
Potential Contributions of Antioxidants to Cancer Therapy: Immunomodulation and Radiosensitization
inferredcites →https://doi.org/10.1177/1758834014521111openalex-snapshot
Anti-inflammatory/antioxidant use in long-term maintenance cancer therapy: a new therapeutic approach to disease progression and recurrence
inferredcites →https://doi.org/10.1186/1476-4598-12-86openalex-snapshot
The complexity of NF-κB signaling in inflammation and cancer
inferredcites →https://doi.org/10.1186/1479-5876-4-48openalex-snapshot
Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment
inferredcites →https://doi.org/10.1186/s12906-016-1452-yopenalex-snapshot
In-vitro alpha amylase inhibitory activity of the leaf extracts of Adenanthera pavonina
inferredcites →https://doi.org/10.1186/s12937-016-0217-2openalex-snapshot
An overview on the role of dietary phenolics for the treatment of cancers
inferredcites →https://doi.org/10.18388/abp.2012_2116openalex-snapshot
NF-κB signaling pathway and free radical impact.
inferredcites →https://doi.org/10.2741/1667openalex-snapshot
Reactive oxygen species in tumor progression
inferredcites →https://doi.org/10.3109/10715761003610760openalex-snapshot
Reassessment of antioxidant activity of arbutin: Multifaceted evaluation using five antioxidant assay systems
inferredcites →https://doi.org/10.3892/ijmm.2017.3256openalex-snapshot
Investigation of the pro-apoptotic effects of arbutin and its acetylated derivative on murine melanoma cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4897438openalex-extracted
Dynamics of the Accumulation and Biological Activities of Active Components in the Aerial Parts of Comfrey (Symphytum Officinale L.)
inferred← citeshttps://doi.org/10.1002/ptr.7076openalex-snapshot
A comprehensive review of the therapeutic potential of α‐arbutin
inferred← citeshttps://doi.org/10.1002/slct.202503446openalex-snapshot
Computational Identification of FDA‐Approved Drugs as Potential BMX Inhibitors: An Integrated Virtual Screening, Pharmacokinetics and Molecular Dynamics Study
inferred← citeshttps://doi.org/10.1007/s11033-024-09488-4openalex-snapshot
Protective effects of arbutin against doxorubicin-induced cardiac damage
inferred← citeshttps://doi.org/10.1007/s12247-026-10669-wopenalex-snapshot
Exploring the Molecular Mechanism of Arbutin as a Potential Inhibitor Against Melanoma: Insights from Network Pharmacology, Molecular Docking, Dynamics Simulations, and DFT Analysis
inferred← citeshttps://doi.org/10.1007/s12672-024-01624-7openalex-snapshot
Research progress on the anti-tumor effects of euphorbia humifusa
inferred← citeshttps://doi.org/10.1007/s12672-024-01729-zopenalex-snapshot
Role of arbutin in the inhibition of FBXO5 in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1016/b978-0-323-85852-6.00021-4openalex-snapshot
Herbal glycosides in healthcare
inferred← citeshttps://doi.org/10.1016/j.cej.2026.172549openalex-snapshot
Research advances in arbutin-based materials: synthesis, encapsulation, applications, and trends
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2024.143305openalex-snapshot
Flubendiamide provokes oxidative stress, inflammation, miRNAs alteration, and cell cycle deregulation in human prostate epithelial cells: The attenuation impact of synthesized nano-selenium using Trichoderma aureoviride
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e32887openalex-snapshot
Temporary alleviation of MAPK by arbutin alleviates oxidative damage in the retina and ARPE-19 cells
inferred← citeshttps://doi.org/10.1016/j.jphotobiol.2025.113100openalex-snapshot
α-arbutin prevents UVA-induced skin photodamage via alleviating DNA damage and collagen degradation in NIH-3T3 cells
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.119005openalex-snapshot
The role of microRNA-338-3p in cancer: growth, invasion, chemoresistance, and mediators
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c07972openalex-snapshot
Efficient Whole-Cell Biotransformation for α-Arbutin Production through the Engineering of Sucrose Phosphorylase Combined with Engineered Cell Modification
inferred← citeshttps://doi.org/10.1038/s41598-023-42177-zopenalex-snapshot
Combined dandelion extract and all-trans retinoic acid induces cytotoxicity in human breast cancer cells
inferred← citeshttps://doi.org/10.1039/d4fo01155dopenalex-snapshot
Exploring the broad-spectrum pharmacological activity of two less studied Australian native fruits: chemical characterisation using LCMS-driven metabolomics
inferred← citeshttps://doi.org/10.1080/07391102.2023.2247080openalex-snapshot
Molecular analysis of dUTPase of Helicobacter pylori for identification of novel inhibitors using in silico studies
inferred← citeshttps://doi.org/10.1080/15287394.2024.2393308openalex-snapshot
Liposome preparation of alpha-arbutin: stability and toxicity assessment using mouse B16F10 melanoma cells
inferred← citeshttps://doi.org/10.1093/rb/rbad114openalex-snapshot
Electrospun PCL/gelatin/arbutin nanofiber membranes as potent reactive oxygen species scavengers to accelerate cutaneous wound healing
inferred← citeshttps://doi.org/10.1186/s11658-024-00591-9openalex-snapshot
The role of proinflammatory cytokines and CXC chemokines (CXCL1–CXCL16) in the progression of prostate cancer: insights on their therapeutic management
inferred← citeshttps://doi.org/10.17219/acem/133493openalex-snapshot
Arbutin inhibits inflammation and apoptosis by enhancing autophagy via SIRT1
inferred← citeshttps://doi.org/10.2174/2215083810666230815142928openalex-snapshot
Nano-based Herbal Medicine: A New Candidate for Prostate Cancer Treatment?
inferred← citeshttps://doi.org/10.30934/kusbed.1678429openalex-snapshot
Synergistic Apoptotic Effects of Cisplatin and Arbutin in MCF-7 Breast Cancer Cells
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1682390openalex-snapshot
Targeting the gut-pancreatic axis: microbial modulation of immunotherapy in pancreatic cancer
inferred← citeshttps://doi.org/10.3389/fonc.2022.951167openalex-snapshot
Role of Interleukin-1 family in bone metastasis of prostate cancer
inferred← citeshttps://doi.org/10.3389/fpubh.2025.1544174openalex-snapshot
Relationship between the level of mixed chemicals in male urine and the prevalence of male cancers, especially prostate cancer
inferred← citeshttps://doi.org/10.3390/antiox10071129openalex-snapshot
Arbutin as a Skin Depigmenting Agent with Antimelanogenic and Antioxidant Properties
inferred← citeshttps://doi.org/10.3390/antiox13020207openalex-snapshot
Molecular Mechanism of Natural Food Antioxidants to Regulate ROS in Treating Cancer: A Review
inferred← citeshttps://doi.org/10.3390/antiox13060625openalex-snapshot
Resveratrol-Enriched Rice Callus Extract Inhibits Oxidative and Cellular Melanogenic Activities in Melan-A Cells
inferred← citeshttps://doi.org/10.3390/cancers13030564openalex-snapshot
Harnessing Tumor Necrosis Factor Alpha to Achieve Effective Cancer Immunotherapy
inferred← citeshttps://doi.org/10.3390/cancers13236062openalex-snapshot
Therapeutic Influence on Important Targets Associated with Chronic Inflammation and Oxidative Stress in Cancer Treatment
inferred← citeshttps://doi.org/10.3390/molecules27248786openalex-snapshot
Arbutin: Occurrence in Plants, and Its Potential as an Anticancer Agent
inferred← citeshttps://doi.org/10.3390/plants14111646openalex-snapshot
Allelopathy and Identification of Allelochemicals in the Leaves of Hakea decurrens subsp. physocarpa W.R. Barker
inferred← citeshttps://doi.org/10.34019/ufjf/di/2022/00030openalex-snapshot
Investigação dos efeitos inibitórios de Eryngium foetidum, (E)-2-dodecenal e arbutina frente a mecanismos oxidativos e enzimas digestivas
inferred← citeshttps://doi.org/10.4236/jbm.2022.102008openalex-snapshot
Contributors to Cancer Susceptibility, Development and Treatment: Cyclic Nucleotides, Steroids and Autophagy Modulators
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