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Biofilm infections, their resilience to therapy and innovative treatment strategies
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2 of the 162 references listed on this page are in the Retraction Watch database as retracted (export 2026-10-28): 10.1016/j.cell.2012.02.055 (notice 2015-05-07), 10.1073/pnas.1100186108 (notice 2018-03-12).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ppul.21193openalex-snapshotGarlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis—a pilot randomized controlled trial
inferredcites →https://doi.org/10.1016/j.ejcb.2009.10.005openalex-snapshotStructure, function and contribution of polysaccharide intercellular adhesin (PIA) to Staphylococcus epidermidis biofilm formation and pathogenesis of biomaterial-associated infections
inferredcites →https://doi.org/10.1016/s0014-5793(99)00036-8openalex-snapshotElevated expression of the CD4 receptor and cell cycle arrest are induced in Jurkat cells by treatment with the novel cyclic dinucleotide 3′,5′‐cyclic diguanylic acid
inferredcites →https://doi.org/10.1021/ja1112029openalex-snapshotConservative Change to the Phosphate Moiety of Cyclic Diguanylic Monophosphate Remarkably Affects Its Polymorphism and Ability To Bind DGC, PDE, and PilZ Proteins
inferredcites →https://doi.org/10.1038/nprot.2010.110openalex-snapshotA 96-well-plate–based optical method for the quantitative and qualitative evaluation of Pseudomonas aeruginosa biofilm formation and its application to susceptibility testing
inferredcites →https://doi.org/10.1039/c0cc05432aopenalex-snapshotc-di-GMP can form remarkably stable G-quadruplexes at physiological conditions in the presence of some planar intercalators
inferredcites →https://doi.org/10.1073/pnas.0511090103openalex-snapshotAnalysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3′-5′)-cyclic-GMP in virulence
inferredcites →https://doi.org/10.1074/jbc.m109.040238openalex-snapshotYybT Is a Signaling Protein That Contains a Cyclic Dinucleotide Phosphodiesterase Domain and a GGDEF Domain with ATPase Activity
inferredcites →https://doi.org/10.1074/jbc.m702800200openalex-snapshotThe Flagellar Sigma Factor FliA Regulates Adhesion and Invasion of Crohn Disease-associated Escherichia coli via a Cyclic Dimeric GMP-dependent Pathway
inferredcites →https://doi.org/10.1084/jem.20082874openalex-snapshotA host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
inferredcites →https://doi.org/10.1093/cid/cir077openalex-snapshotBiofilm Elimination on Intravascular Catheters: Important Considerations for the Infectious Disease Practitioner
inferredcites →https://doi.org/10.1093/jac/dkh223openalex-snapshotSynthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice
inferredcites →https://doi.org/10.1093/jac/dks002openalex-snapshotSynergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model
inferredcites →https://doi.org/10.1111/j.1462-2920.2007.01366.xopenalex-snapshotPseudomonas aeruginosa cupA ‐encoded fimbriae expression is regulated by a GGDEF and EAL domain‐dependent modulation of the intracellular level of cyclic diguanylate
inferredcites →https://doi.org/10.1111/j.1749-4486.2009.01973.xopenalex-snapshotA controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic‐resistant Pseudomonas aeruginosa ; a preliminary report of efficacy
inferredcites →https://doi.org/10.1128/aac.01496-10openalex-snapshotA New Small Molecule Specifically Inhibits the Cariogenic Bacterium Streptococcus mutans in Multispecies Biofilms
inferredcites →https://doi.org/10.1128/aem.01233-10openalex-snapshotModulation of Pseudomonas aeruginosa Biofilm Dispersal by a Cyclic-Di-GMP Phosphodiesterase with a Putative Hypoxia-Sensing Domain
inferredcites →https://doi.org/10.1128/iai.00488-12openalex-snapshotPneumococcal Interactions with Epithelial Cells Are Crucial for Optimal Biofilm Formation and Colonization In Vitro and In Vivo
inferredcites →https://doi.org/10.1128/iai.00999-10openalex-snapshotTheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides
inferredcites →https://doi.org/10.1128/iai.05320-11openalex-snapshotCyclic Dimeric GMP Signaling Regulates Intracellular Aggregation, Sessility, and Growth of Ehrlichia chaffeensis
inferredcites →https://doi.org/10.1128/iai.06286-11openalex-snapshotHyperinduction of Host Beta Interferon by a Listeria monocytogenes Strain Naturally Overexpressing the Multidrug Efflux Pump MdrT
inferredcites →https://doi.org/10.1128/jb.00119-09openalex-snapshotPseudomonas aeruginosa Rugose Small-Colony Variants Have Adaptations That Likely Promote Persistence in the Cystic Fibrosis Lung
inferredcites →https://doi.org/10.1128/jb.00466-08openalex-snapshotInterplay between Cyclic AMP-Cyclic AMP Receptor Protein and Cyclic di-GMP Signaling in Vibrio cholerae Biofilm Formation
inferredcites →https://doi.org/10.1128/jb.00720-06openalex-snapshotDifferentiation and Distribution of Colistin- and Sodium Dodecyl Sulfate-Tolerant Cells in Pseudomonas aeruginosa Biofilms
inferredcites →https://doi.org/10.1128/jb.00975-09openalex-snapshotNitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal
inferredcites →https://doi.org/10.1128/jb.01195-08openalex-snapshotBacteria Possessing Two RelA/SpoT-Like Proteins Have Evolved a Specific Stringent Response Involving the Acyl Carrier Protein-SpoT Interaction
inferredcites →https://doi.org/10.1128/jb.01218-08openalex-snapshotThe Anaplasma phagocytophilum PleC Histidine Kinase and PleD Diguanylate Cyclase Two-Component System and Role of Cyclic Di-GMP in Host Cell Infection
inferredcites →https://doi.org/10.1128/jb.01460-10openalex-snapshotIdentification and Characterization of CdgB, a Diguanylate Cyclase Involved in Developmental Processes in Streptomyces coelicolor
inferredcites →https://doi.org/10.1128/jb.01726-08openalex-snapshotThe Molecular Alarmone (p)ppGpp Mediates Stress Responses, Vancomycin Tolerance, and Virulence inEnterococcus faecalis
inferredcites →https://doi.org/10.1128/mbio.00029-12openalex-snapshotBacteriophages ϕMR299-2 and ϕNH-4 Can Eliminate Pseudomonas aeruginosa in the Murine Lung and on Cystic Fibrosis Lung Airway Cells
inferredcites →https://doi.org/10.1186/1471-2164-10-291openalex-snapshotComprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH)
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1002/adma.201903513openalex-snapshotValidating a Predictive Structure–Property Relationship by Discovery of Novel Polymers which Reduce Bacterial Biofilm Formation
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inferred← citeshttps://doi.org/10.1002/advs.201900599openalex-snapshotHighly Effective and Noninvasive Near‐Infrared Eradication of a Staphylococcus aureus Biofilm on Implants by a Photoresponsive Coating within 20 Min
inferred← citeshttps://doi.org/10.1002/alr.22360openalex-snapshotKappa‐carrageenan sinus rinses reduce inflammation and intracellular Staphylococcus aureus infection in airway epithelial cells
inferred← citeshttps://doi.org/10.1002/app.49088openalex-snapshotAntibacterial effect of nanometer‐size grafted layer of quaternary ammonium polymer on poly(ether ether ketone) substrate
inferred← citeshttps://doi.org/10.1002/celc.202400691openalex-snapshotWireless Potentiometric Monitoring of Microbial Biofilm Formation: In Vitro and Ex Vivo Studies of Gram‐Positive and Gram‐Negative Bacteria
inferred← citeshttps://doi.org/10.1002/jbm.b.34821openalex-snapshotLactobacillus cell‐free supernatant as a novel bioagent and biosurfactant against Pseudomonas aeruginosa in the prevention and treatment of orthopedic implant infection
inferred← citeshttps://doi.org/10.1002/jobm.201300091openalex-snapshotPqs R ‐dependent and Pqs R ‐independent regulation of motility and biofilm formation by PQS in Pseudomonas aeruginosa PAO1
inferred← citeshttps://doi.org/10.1002/jor.25345openalex-snapshotCurrent treatments for biofilm‐associated periprosthetic joint infection and new potential strategies
inferred← citeshttps://doi.org/10.1002/mabi.202100150openalex-snapshotEnhanced Eradication of Mucin‐Embedded Bacterial Biofilm by Locally Delivered Antibiotics in Functionalized Microcontainers
inferred← citeshttps://doi.org/10.1002/mabi.202300519openalex-snapshotIt Takes Two to Tangle: Microneedle Patches Co‐delivering Monoclonal Antibodies and Engineered Antimicrobial Peptides Effectively Eradicate Wound Biofilms
inferred← citeshttps://doi.org/10.1002/mbo3.70391openalex-snapshotEffect of Green‐Synthesized Silver Nanoparticles From Nepeta pogonosperma and Astrodaucus persicus on the Reduction of Bap Gene Expression in Strong Biofilm‐Producing Acinetobacter baumannii Clinical Isolates
inferred← citeshttps://doi.org/10.1002/psc.2895openalex-snapshotAnti-biofilm and sporicidal activity of peptides based on wheat puroindoline and barley hordoindoline proteins
inferred← citeshttps://doi.org/10.1002/slct.202502768openalex-snapshotBiological and Computational Study of the Dual Antimicrobial and Anticancer Potential of 3,4‐Dihydropyrimidin‐2(1 H )‐ones and Thiones
inferred← citeshttps://doi.org/10.1007/5584_2016_93openalex-snapshotActivity of Norspermidine on Bacterial Biofilms of Multidrug-Resistant Clinical Isolates Associated with Persistent Extremity Wound Infections
inferred← citeshttps://doi.org/10.1007/s00018-022-04292-4openalex-snapshotListeria monocytogenes exposed to antimicrobial peptides displays differential regulation of lipids and proteins associated to stress response
inferred← citeshttps://doi.org/10.1007/s00203-025-04603-wopenalex-snapshotComparative analysis of quorum sensing mechanisms in Pseudomonas aeruginosa and Klebsiella pneumoniae: implications for antibiotic resistance
inferred← citeshttps://doi.org/10.1007/s00253-013-4875-0openalex-snapshotThe immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability
inferred← citeshttps://doi.org/10.1007/s10482-018-1045-5openalex-snapshotNegative pressure wound therapy reduces the motility of Pseudomonas aeruginosa and enhances wound healing in a rabbit ear biofilm infection model
inferred← citeshttps://doi.org/10.1007/s10856-014-5333-yopenalex-snapshotStructural and biological evaluation of lignin addition to simple and silver-doped hydroxyapatite thin films synthesized by matrix-assisted pulsed laser evaporation
inferred← citeshttps://doi.org/10.1007/s10965-020-02308-wopenalex-snapshotPotential of electrospun cellulose acetate nanofiber mat integrated with silver nanoparticles from Azadirachta indica as antimicrobial agent
inferred← citeshttps://doi.org/10.1007/s11259-021-09881-5openalex-snapshotCharacterization and antimicrobial susceptibility of biofilm-producing Avian Pathogenic Escherichia coli from broiler chickens and their environment in India
inferred← citeshttps://doi.org/10.1007/s11274-015-1884-4openalex-snapshotA central composite rotatable design (CCRD) approach to study the combined effect of antimicrobial agents against bacterial pathogens
inferred← citeshttps://doi.org/10.1007/s11274-022-03339-9openalex-snapshotEffect of quorum quenchers on virulence factors production and quorum sensing signalling pathway of non-mucoid, mucoid, and heavily mucoid Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1007/s12010-020-03330-wopenalex-snapshotMechanisms of Action of Luteolin Against Single- and Dual-Species of Escherichia coli and Enterobacter cloacae and Its Antibiofilm Activities
inferred← citeshttps://doi.org/10.1007/s12010-022-04231-wopenalex-snapshotEfficient Inhibition of Bacterial Biofilm Through Interference of Protein–Protein Interaction of Master Regulator Proteins: a Proof of Concept Study with SinR- SinI Complex of Bacillus subtilis
inferred← citeshttps://doi.org/10.1007/s12033-021-00371-2openalex-snapshotAlternatives to Conventional Antibiotic Therapy: Potential Therapeutic Strategies of Combating Antimicrobial-Resistance and Biofilm-Related Infections
inferred← citeshttps://doi.org/10.1016/j.bcab.2021.102209openalex-snapshotCurrent strategies in inhibiting biofilm formation for combating urinary tract infections: Special focus on peptides, nano-particles and phytochemicals
inferred← citeshttps://doi.org/10.1016/j.bcab.2025.103515openalex-snapshotA DNase from halophilic bacterium Bacillus pacificus targets two notorious biofilms of Pseudomonas aeruginosa PAO1 and Staphylococcus aureus
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.110324openalex-snapshotDesign and synthesis of novel thiazolotriazole–sulfonamide hybrids tackling antimicrobial resistance: mechanistic insights into efflux pump inhibitor, gene downregulation, and machine-aided results
inferred← citeshttps://doi.org/10.1016/j.bmc.2018.08.032openalex-snapshotAmphipathic sulfonamidobenzamides mimicking small antimicrobial marine natural products; investigation of antibacterial and anti-biofilm activity against antibiotic resistant clinical isolates
inferred← citeshttps://doi.org/10.1016/j.bmcl.2014.09.009openalex-snapshotDiscovery of quinoline small molecules with potent dispersal activity against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a scaffold hopping strategy
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.06.065openalex-snapshotAntibiofilm potential of 16-oxo-cleroda-3, 13(14) E-diene-15 oic acid and its five new γ-amino γ-lactone derivatives against methicillin resistant Staphylococcus aureus and Streptococcus mutans
inferred← citeshttps://doi.org/10.1016/j.ica.2013.12.006openalex-snapshotSynthesis and characterization of two cyanoxime ligands, their precursors, and light insensitive antimicrobial silver(I) cyanoximates
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2021.02.040openalex-snapshotEcofriendly novel synthesis of tertiary composite based on cellulose and myco-synthesized selenium nanoparticles: Characterization, antibiofilm and biocompatibility
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.128066openalex-snapshotPreparation, characterization, and Staphylococcus aureus biofilm elimination effect of baicalein-loaded tyrosine/hyaluronic acid/β-cyclodextrin-grafted chitosan nano-delivery system
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