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Symmetric Dimethylarginine Assay Validation, Stability, and Evaluation as a Marker for the Early Detection of Chronic Kidney Disease in Dogs

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/hep.20579openalex-snapshot

The human liver clears both asymmetric and symmetric dimethylarginine†

inferredcites →https://doi.org/10.1007/s00125-005-0066-6openalex-snapshot

Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover

inferredcites →https://doi.org/10.1007/s00335-002-2253-9openalex-snapshot

Genetic cause of X-linked Alport syndrome in a family of domestic dogs

inferredcites →https://doi.org/10.1016/j.rvsc.2005.07.005openalex-snapshot

Body size, but neither age nor asymptomatic mitral regurgitation, influences plasma concentrations of dimethylarginines in dogs

inferredcites →https://doi.org/10.1016/j.rvsc.2006.09.003openalex-snapshot

Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs

inferredcites →https://doi.org/10.1016/j.tvjl.2014.10.021openalex-snapshot

Comparison of serum concentrations of symmetric dimethylarginine and creatinine as kidney function biomarkers in healthy geriatric cats fed reduced protein foods enriched with fish oil, L-carnitine, and medium-chain triglycerides

inferredcites →https://doi.org/10.1016/s0021-9258(18)62716-4openalex-snapshot

Isolation and Identification of N,N- and N,N' -Dimethylarginine, Nε-Mono-, Di-, and Trimethyllysine, and Glucosylgalactosyl- and Galactosyl-δ-hydroxylysine from Human Urine

inferredcites →https://doi.org/10.1038/nrneph.2011.31openalex-snapshot

The role of asymmetric and symmetric dimethylarginines in renal disease

inferredcites →https://doi.org/10.1042/bj1540179openalex-snapshot

Studies on the catabolism of NG-methylarginine, NG, NG-dimethylarginine and NG, NG-dimethylarginine in the rabbit

inferredcites →https://doi.org/10.1093/clinchem/43.8.1429openalex-snapshot

Measurement of serum iohexol by determination of iodine with inductively coupled plasma–atomic emission spectroscopy

inferredcites →https://doi.org/10.1093/ndt/gfl292openalex-snapshot

Symmetric dimethylarginine (SDMA) as endogenous marker of renal function—a meta-analysis

inferredcites →https://doi.org/10.1093/ndt/gfs554openalex-snapshot

Effects of chronic SDMA infusion on glomerular filtration rate, blood pressure, myocardial function and renal histology in C57BL6/J mice

inferredcites →https://doi.org/10.1111/j.1939-1676.2012.00891.xopenalex-snapshot

Urinary Biomarkers of Renal Disease in Dogs with X-Linked Hereditary Nephropathy

inferredcites →https://doi.org/10.1111/jvim.12445openalex-snapshot

Comparison of Serum Concentrations of Symmetric Dimethylarginine and Creatinine as Kidney Function Biomarkers in Cats with Chronic Kidney Disease

inferredcites →https://doi.org/10.1111/jvim.12446openalex-snapshot

Relationship between Serum Symmetric Dimethylarginine Concentration and Glomerular Filtration Rate in Cats

inferredcites →https://doi.org/10.1111/jvim.12607openalex-snapshot

Relationship between lean body mass and serum renal biomarkers in healthy dogs

inferredcites →https://doi.org/10.1152/ajprenal.1990.258.3.f495openalex-snapshot

Single-nephron adaptations to partial renal ablation in the dog

inferredcites →https://doi.org/10.1201/ebk1439808184openalex-snapshot

Testing Statistical Hypotheses of Equivalence and Noninferiority

inferredcites →https://doi.org/10.1371/journal.pone.0096875openalex-snapshot

Incidence of All-Cause and Cardiovascular Mortality Predicted by Symmetric Dimethylarginine in the Population-Based Study of Health in Pomerania

inferredcites →https://doi.org/10.1515/cclm-2014-0314openalex-snapshot

Serum reference intervals of homoarginine, ADMA, and SDMA in the Study of Health in Pomerania

inferredcites →https://doi.org/10.1681/asn.2006040367openalex-snapshot

Role of Nitric Oxide–Producing and–Degrading Pathways in Coronary Endothelial Dysfunction in Chronic Kidney Disease

inferredcites →https://doi.org/10.2215/cjn.01720211openalex-snapshot

Symmetric Dimethylarginine as a Proinflammatory Agent in Chronic Kidney Disease

inferredcites →https://doi.org/10.2460/ajvr.1999.60.03.373openalex-snapshot

New form of X-linked dominant hereditary nephritis in dogs

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Symmetric Dimethylarginine Evaluation and Characterization of Proteinuria in Dogs with ACTH-Dependent Hyperadrenocorticism

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Renal Anatomy, Physiology, and Evaluation of Function

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The Kidney

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Evaluation of symmetric dimethylarginine and creatinine in dogs with primary hypoadrenocorticism receiving long‐term mineralocorticoid replacement therapy

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Diagnostic accuracy of symmetric dimethylarginine for chronic kidney disease in cats and dogs: A systematic review

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Machine Learning Model for Chronic Kidney Disease Prediction in Canines

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Serum symmetric dimethylarginine levels in a half-breed German shepherd dog with renal cystadenocarcinoma and nodular dermatofibrosis

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First automated immunoassay for symmetric dimethylarginine (SDMA) with reference interval establishment

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Symmetric Dimethylarginine

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Risk of Development of Chronic Kidney Disease After Exposure to Borrelia burgdorferi and Anaplasma spp

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Serum Symmetric Dimethylarginine Concentration in Greyhound Pups and Adults

inferred← citeshttps://doi.org/10.1016/j.tcam.2021.100580openalex-snapshot

Cystatin C and Neutrophil Gelatinase-Associated Lipocalin as Early Biomarkers for Chronic Kidney Disease in Dogs

inferred← citeshttps://doi.org/10.1016/j.tcam.2022.100674openalex-snapshot

Comparative Efficacy of Antihypertensive Drugs in Dogs: A Systematic Review

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inferred← citeshttps://doi.org/10.1016/j.tvjl.2019.05.010openalex-snapshot

Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs

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inferred← citeshttps://doi.org/10.1016/j.tvjl.2021.105729openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.tvjl.2021.105732openalex-snapshot

Longitudinal evaluation of symmetric dimethylarginine and concordance of kidney biomarkers in cats and dogs

inferred← citeshttps://doi.org/10.1016/j.tvjl.2024.106108openalex-snapshot

Description of serum symmetric dimethylarginine concentration and of urinary SDS-AGE pattern in dogs with ACTH dependent hyperadrenocorticism

inferred← citeshttps://doi.org/10.1016/j.vetpar.2019.109015openalex-snapshot

Evaluation of serum symmetric dimethylarginine as a biomarker of kidney disease in canine leishmaniosis due to Leishmania infantum

inferred← citeshttps://doi.org/10.1016/j.vetpar.2020.109144openalex-snapshot

Evaluation of serum biomarkers and proteinuria for the early detection of renal damage in dogs with heartworm (Dirofilaria immitis)

inferred← citeshttps://doi.org/10.1016/j.vetpar.2023.109930openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.vetpar.2024.110251openalex-snapshot

Urinary neutrophil gelatinase-associated lipocalin as early biomarker for renal disease in dogs with leishmaniosis

inferred← citeshttps://doi.org/10.1021/acs.jproteome.0c00116openalex-snapshot

Improved Discrimination of Asymmetric and Symmetric Arginine Dimethylation by Optimization of the Normalized Collision Energy in Liquid Chromatography–Mass Spectrometry Proteomics

inferred← citeshttps://doi.org/10.1038/s41598-018-34321-xopenalex-snapshot

Fearful dogs have increased plasma glutamine and γ-glutamyl glutamine

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inferred← citeshttps://doi.org/10.1053/j.jepm.2024.02.002openalex-snapshot

Assay validation and determination of the reference interval for symmetric dimethylarginine in healthy rabbits

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inferred← citeshttps://doi.org/10.1292/jvms.19-0694openalex-snapshot

Comparison of pancreatic and renal blood flow in a canine tachycardia-induced cardiomyopathy model

inferred← citeshttps://doi.org/10.1292/jvms.20-0125openalex-snapshot

Biomarkers for chronic kidney disease in dogs: a comparison study

inferred← citeshttps://doi.org/10.1292/jvms.20-0574openalex-snapshot

Iron status and erythropoiesis response to darbepoetin alfa in dogs with chronic kidney disease

inferred← citeshttps://doi.org/10.1371/journal.pone.0168343openalex-snapshot

X-Linked Alport Dogs Demonstrate Mesangial Filopodial Invasion of the Capillary Tuft as an Early Event in Glomerular Damage

inferred← citeshttps://doi.org/10.1371/journal.pone.0205030openalex-snapshot

Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum

inferred← citeshttps://doi.org/10.1371/journal.pone.0227964openalex-snapshot

A retrospective evaluation of the relationship between symmetric dimethylarginine, creatinine and body weight in hyperthyroid cats

inferred← citeshttps://doi.org/10.1371/journal.pone.0238440openalex-snapshot

Symmetric dimethylarginine in dogs with myxomatous mitral valve disease at various stages of disease severity

inferred← citeshttps://doi.org/10.1371/journal.pone.0247049openalex-snapshot

Serum symmetric dimethylarginine shows a relatively consistent long-term concentration in healthy dogs with a significant effect of increased body fat percentage

inferred← citeshttps://doi.org/10.1371/journal.pone.0269085openalex-snapshot

Evaluation of renal injury and function biomarkers, including symmetric dimethylarginine (SDMA), in the rat passive Heymann nephritis (PHN) model

inferred← citeshttps://doi.org/10.1371/journal.pone.0293545openalex-snapshot

Novel renal injury markers in dogs with ehrlichiosis

inferred← citeshttps://doi.org/10.1371/journal.pone.0311406openalex-snapshot

Glomerular filtration rate determined by measuring serum clearance of iohexol in unanesthetized cheetahs (Acinonyx jubatus) with comparison to serum symmetric dimethylarginine

inferred← citeshttps://doi.org/10.15421/022039openalex-snapshot

Macronutrient status and indicators of acid-alkaline blood balance in cats with chronic renal failure

inferred← citeshttps://doi.org/10.1638/2016-0224.1openalex-snapshot

EVALUATION OF SYMMETRIC DIMETHYLARGININE AS AN EARLY BIOMARKER OF CHRONIC KIDNEY DISEASE IN CAPTIVE CHEETAHS (ACINONYX JUBATUS)

inferred← citeshttps://doi.org/10.1638/2017-0056.1openalex-snapshot

RETROSPECTIVE ANALYSIS AND VALIDATION OF SERUM SYMMETRIC DIMETHYLARGININE (SDMA) CONCENTRATIONS IN CHEETAHS (ACINONYX JUBATUS)

inferred← citeshttps://doi.org/10.1638/2020-0032openalex-snapshot

COMPARISON OF BLOOD SYMMETRIC DIMETHYLARGININE AND CREATININE AS ENDOGENOUS MARKERS OF KIDNEY FUNCTION IN CAPTIVE TIGERS (PANTHERA TIGRIS)

inferred← citeshttps://doi.org/10.1638/2020-0218openalex-snapshot

USE OF SYMMETRIC DIMETHYLARGININE TO DETECT RENAL LESIONS IN FISH: A PRELIMINARY STUDY IN BROOK TROUT (SALVELINUS FONTINALIS)

inferred← citeshttps://doi.org/10.1638/2021-0067openalex-snapshot

METHOD COMPARISON FOR MEASUREMENT OF SYMMETRIC DIMETHYLARGININE IN TIGERS (PANTHERA TIGRIS)

inferred← citeshttps://doi.org/10.1638/2021-0133openalex-snapshot

PRELIMINARY EVALUATION OF SYMMETRIC DIMETHYLARGININE AS A BIOMARKER OF RENAL INSUFFICIENCY IN WILD AND REHABILITATED FLORIDA MANATEES (TRICHECHUS MANATUS LATIROSTRIS)

inferred← citeshttps://doi.org/10.1638/2021-0134openalex-snapshot

EVALUATION OF SYMMETRIC DIMETHYLARGININE AS AN ENDOGENOUS MARKER OF RENAL DISEASE IN GREATER FLAMINGOS (PHOENICOPTERUS ROSEUS)

inferred← citeshttps://doi.org/10.1638/2024-0025openalex-snapshot

ESTABLISHMENT OF REFERENCE INTERVAL FOR SYMMETRIC DIMETHYLARGININE IN HAMADRYAS BABOONS (PAPIO HAMADRYAS)

inferred← citeshttps://doi.org/10.1638/2024-0061openalex-snapshot

DETERMINATION OF SYMMETRIC DIMETHYLARGININE, CREATININE, AND BLOOD UREA NITROGEN REFERENCE INTERVALS IN AFRICAN WILD DOGS (LYCAON PICTUS) IN MANAGED CARE FROM TWO ZOOLOGICAL INSTITUTIONS IN THE UNITED KINGDOM

inferred← citeshttps://doi.org/10.1638/2025-0095openalex-snapshot

Evaluation of serum symmetric dimethylarginine as a renal biomarker in Asian elephants (Elephas maximus)

inferred← citeshttps://doi.org/10.1638/2025-0100openalex-snapshot

Symmetric dimethylarginine and renal disease evaluation in greater kudu (Tragelaphus strepsiceros )

inferred← citeshttps://doi.org/10.1647/avianms-d-24-00003openalex-snapshot

Reference Interval Creation for Symmetric Dimethylarginine (SDMA) in Healthy Hispaniolan Amazon Parrots (Amazona ventralis) and Quaker Parrots (Myiopsitta monachus)

inferred← citeshttps://doi.org/10.17221/77/2017-vetmedopenalex-snapshot

Indirect markers of glomerular filtration rate in dogs and cats: a review

inferred← citeshttps://doi.org/10.18002/10612/6907openalex-snapshot

Aplicación de la imagenología a la clínica del aparato urogenital canino = Application of imaging to the clinic of the urogenital canine apparatus

inferred← citeshttps://doi.org/10.18805/ijar.bf-1654openalex-snapshot

Comparison of Asymmetric Dimethyl Arginine and Oxidative Stress Parameters in Obese Dogs and Dogs with Clinically Normal Body Condition Based on Routine Hemogram and Serum Biochemicals

inferred← citeshttps://doi.org/10.21203/rs.2.11677/v1openalex-snapshot

Correlation between separate findings in 60 dogs suffering from CKD in IRIS stage 1

inferred← citeshttps://doi.org/10.21203/rs.2.11677/v2openalex-snapshot

Correlation between separate findings in 60 dogs suffering from CKD in IRIS stage 1

inferred← citeshttps://doi.org/10.21203/rs.3.rs-591312/v1openalex-snapshot

Alteration in Serum Cystatin-C and SDMA as biomarkers of early renal dysfunction associated with Canine Monocytic Ehrlichiosis (CME)

inferred← citeshttps://doi.org/10.21708/avb.2020.14.4.9322openalex-snapshot

Chronic kidney disease in a dog of the Teckel breed: case report

inferred← citeshttps://doi.org/10.21825/vdt.v87i3.16076openalex-snapshot

Succesvolle behandeling van een solitaire simpele renale cyste bij een hond

inferred← citeshttps://doi.org/10.21897/rmvz.2782openalex-snapshot

Correlación de biomarcadores de función renal en el primer acercamiento diagnóstico de la enfermedad renal crónica en perros

inferred← citeshttps://doi.org/10.22456/1679-9216.102937openalex-snapshot

A Transversal Study of Biochemical Profile, Urinalysis, UPC, Electrolytes and Blood Pressure in Dogs with Chronic Kidney Disease

inferred← citeshttps://doi.org/10.2460/ajvr.21.09.0150openalex-snapshot

Short course of immune-suppressive doses of prednisolone, evaluated through a prospective double-masked placebo-controlled clinical trial in healthy Beagles, is associated with sustained modifications in renal, hydration, and electrolytic status

inferred← citeshttps://doi.org/10.2460/ajvr.22.12.0222openalex-snapshot

Adult chicken hens (Gallus gallus) have measurable circulating plasma symmetric dimethylarginine via liquid chromatography–tandem mass spectrometry

inferred← citeshttps://doi.org/10.2460/ajvr.24.07.0204openalex-snapshot

Comparison of 2 point-of-care analyzers and the Eurolyser assay with an IDEXX reference laboratory method for measurement of symmetric dimethylarginine in dogs

inferred← citeshttps://doi.org/10.2460/ajvr.81.4.375openalex-snapshot

Glomerular filtration rate determined by measuring serum clearance of a single dose of inulin and serum symmetric dimethylarginine concentration in clinically normal cheetahs (Acinonyx jubatus)

inferred← citeshttps://doi.org/10.2460/javma.21.04.0216openalex-snapshot

Blood concentration of symmetric dimethylarginine correlates with kidney damage as assessed with a proposed histologic grading system for chronic kidney disease in tigers (Panthera tigris)

inferred← citeshttps://doi.org/10.2460/javma.21.06.0272openalex-snapshot

Long-term follow-up of a juvenile simple renal cyst in a dog treated by laparoscopic deroofing, fulguration, and omentalization

inferred← citeshttps://doi.org/10.2460/javma.22.07.0320openalex-snapshot

No adverse consequences associated with targeting clinical signs to initiate antimicrobial treatment of postoperative subclinical bacteriuria in dogs following surgical decompression of Hansen type I thoracolumbar disk herniation

inferred← citeshttps://doi.org/10.2478/acve-2022-0033openalex-snapshot

Symmetric Dimethylarginine is a Promising Biomarker for the Early Detection of Age-Related Kidney Dysfunction in Zoo Felids

inferred← citeshttps://doi.org/10.26512/2018.tcc.22419openalex-snapshot

Marcadores precoces de lesão renal em cães e gatos domésticos : revisão de literatura

inferred← citeshttps://doi.org/10.26843/investigacao.v16i8.1863openalex-snapshot

CONCEITOS E APLICABILIDADE DOS PRINCIPAIS BIOMARCADORES NA NEFROLOGIA VETERINÁRIA – REVISÃO DE LITERATURA

inferred← citeshttps://doi.org/10.29244/avl.8.2.35-36openalex-snapshot

Symmetry dimethylarginine (SDMA) assay for diagnosis of kidney disease in dogs and cats: a mini review of case reports in Indonesia between 2021-2023

inferred← citeshttps://doi.org/10.30607/kvj.1880986openalex-snapshot

Age-Related Comparison of Serum Symmetrical Dimethylarginine Levels and Urea, Creatinine Levels in Hair Goats

inferred← citeshttps://doi.org/10.30802/aalas-cm-22-000084openalex-snapshot

Effects of Mouse Kidney Parvovirus on Pharmacokinetics of Chemotherapeutics and the Adenine Model of Chronic Kidney Disease

inferred← citeshttps://doi.org/10.31533/pubvet.v16n11a1254.1-9openalex-snapshot

Doença renal crônica em pequenos animais e biomarcadores que visem sua precocidade

inferred← citeshttps://doi.org/10.3389/fvets.2021.738898openalex-snapshot

Plasmatic Dimethylarginines in Dogs With Myxomatous Mitral Valve Disease

inferred← citeshttps://doi.org/10.3389/fvets.2022.824748openalex-snapshot

Symmetrical Dimethylarginine as a Diagnostic Parameter in Hermann's Tortoises (Testudo hermanni)

inferred← citeshttps://doi.org/10.3389/fvets.2026.1747860openalex-snapshot

Physiological baseline of conscious tigers: expanded diagnostic framework integrating renal, electrolyte and cardiorenal biomarkers in Panthera tigris

inferred← citeshttps://doi.org/10.3390/ani10061000openalex-snapshot

Pharmacokinetic Profile of Oral Administration of Mefloquine to Clinically Normal Cats: A Preliminary In-Vivo Study of a Potential Treatment for Feline Infectious Peritonitis (FIP)

inferred← citeshttps://doi.org/10.3390/ani11061748openalex-snapshot

Measurement of Selected Renal Biochemical Parameters in Healthy Adult Donkeys Considering the Influence of Gender, Age and Blood Freezing

inferred← citeshttps://doi.org/10.3390/ani12030262openalex-snapshot

Drug-Dosing Adjustment in Dogs and Cats with Chronic Kidney Disease

inferred← citeshttps://doi.org/10.3390/ani12223192openalex-snapshot

Outcome of Acquired Fanconi Syndrome Associated with Ingestion of Jerky Treats in 30 Dogs

inferred← citeshttps://doi.org/10.3390/ani14091305openalex-snapshot

A Pilot Study of the Role of Selected Biomarkers of Kidney Injury in Dogs with Dilated Cardiomyopathy

inferred← citeshttps://doi.org/10.3390/ani14162313openalex-snapshot

Early Detection of Chronic Kidney Disease Using Plasma Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 in Small-Breed Dogs: A Retrospective Pilot Study

inferred← citeshttps://doi.org/10.3390/ani15060818openalex-snapshot

Renal Biomarkers in Companion Animals—A Review

inferred← citeshttps://doi.org/10.3390/ani15131940openalex-snapshot

High Prevalence of Lesions of Systemic Hypertension in Bile-Extracted Asiatic Black Bears (Ursus thibetanus) and Associated Renal Disease

inferred← citeshttps://doi.org/10.3390/ani15142003openalex-snapshot

Urinary NGAL as an Early Marker of Renal Dysfunction in Dogs with Heartworm Disease and Pulmonary Hypertension

inferred← citeshttps://doi.org/10.3390/ani15182760openalex-snapshot

Serum Creatinine, Cystatin C and Symmetric Dimethylarginine Concentrations and Relationship Between Them in Healthy Small and Miniature Dogs: A Preliminary Study

inferred← citeshttps://doi.org/10.3390/vetsci12050436openalex-snapshot

Urinary Gamma-Glutamil Transferase as an Early Biomarker of Renal Disease in Dogs with Leishmaniosis

inferred← citeshttps://doi.org/10.3390/vetsci13090852openalex-snapshot

Short-Term Renal Effects of Add-On Levetiracetam in Client-Owned Dogs with Idiopathic Epilepsy Receiving Phenobarbital: A Four-Week Prospective Study

inferred← citeshttps://doi.org/10.3390/vetsci13090881openalex-snapshot

Serum Cystatin C and the Urinary NAG Index Identify an Altered Renal Biochemical Phenotype in Clinically Healthy Geriatric Dogs with Normal Serum Creatinine: A Three-Tier Cross-Sectional Study

inferred← citeshttps://doi.org/10.3390/vetsci7020072openalex-snapshot

Evaluation of Symmetric Dimethylarginine (SDMA) in Dogs with Acute Pancreatitis

inferred← citeshttps://doi.org/10.3390/vetsci8080146openalex-snapshot

Alterations of Serum Biochemical and Urinary Parameters in a Canine Population before and after Intravenous Contrast Administration

inferred← citeshttps://doi.org/10.3390/vetsci8110263openalex-snapshot

Use of Levetiracetam in Epileptic Dogs with Chronic Kidney Disease: A Retrospective Study

inferred← citeshttps://doi.org/10.34067/kid.0006542020openalex-snapshot

Evaluation of Renal Biomarkers, Including Symmetric Dimethylarginine, following Gentamicin-Induced Proximal Tubular Injury in the Rat

inferred← citeshttps://doi.org/10.35229/jaes.1830234openalex-snapshot

Köpek ve Kedilerde Böbrek Hastalıklarında Biyobelirteçlerin Klinik Kullanımı

inferred← citeshttps://doi.org/10.37275/bsm.v7i9.866openalex-snapshot

Symmetric Dimethylarginine as a Biomarker for Chronic Kidney Disease

inferred← citeshttps://doi.org/10.4142/jvs.23101openalex-snapshot

Diagnostic assessment of two-dimensional shear wave elastography in relation to dimethyl arginine levels in dogs with chronic kidney disease

inferred← citeshttps://doi.org/10.4142/jvs.23268openalex-snapshot

Symmetric dimethylarginine correlates with the urea, creatinine, potassium, and clinical scores in feline urethral obstructions

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