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A Feline-Specific Anti-Nerve Growth Factor Antibody Improves Mobility in Cats with Degenerative Joint Disease–Associated Pain: A Pilot Proof of Concept Study
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/s40265-014-0208-6openalex-snapshot
Targeting Nerve Growth Factor (NGF) for Pain Management: What Does the Future Hold for NGF Antagonists?
inferredcites →https://doi.org/10.1016/j.jfms.2007.10.007openalex-snapshot
Long-term safety, efficacy and palatability of oral meloxicam at 0.01–0.03 mg/kg for treatment of osteoarthritic pain in cats
inferredcites →https://doi.org/10.1016/j.jfms.2011.06.008openalex-snapshot
Retrospective Case—Control Study of the Effects of Long-Term Dosing with Meloxicam on Renal Function in Aged Cats with Degenerative Joint Disease
inferredcites →https://doi.org/10.1016/j.joca.2013.06.004openalex-snapshot
Nerve growth factor: an update on the science and therapy
inferredcites →https://doi.org/10.1016/j.joca.2014.10.003openalex-snapshot
A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee
inferredcites →https://doi.org/10.1016/j.tvjl.2009.12.014openalex-snapshot
Cross-sectional study of the prevalence and clinical features of osteoarthritis in 100 cats
inferredcites →https://doi.org/10.1016/j.tvjl.2012.12.015openalex-snapshot
Reliability and discriminatory testing of a client-based metrology instrument, feline musculoskeletal pain index (FMPI) for the evaluation of degenerative joint disease-associated pain in cats
inferredcites →https://doi.org/10.1056/nejmoa0901510openalex-snapshot
Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee
inferredcites →https://doi.org/10.1111/j.1467-2995.2007.00367.xopenalex-snapshot
Evaluation of a digitally integrated accelerometer-based activity monitor for the measurement of activity in cats
inferredcites →https://doi.org/10.1111/j.1532-950x.2010.00708.xopenalex-snapshot
Cross-Sectional Study of the Prevalence of Radiographic Degenerative Joint Disease in Domesticated Cats
inferredcites →https://doi.org/10.1111/j.1939-1676.2007.tb02983.xopenalex-snapshot
Evaluation of Client-Specific Outcome Measures and Activity Monitoring to Measure Pain Relief in Cats with Osteoarthritis
inferredcites →https://doi.org/10.1111/jvim.12077openalex-snapshot
Feline Musculoskeletal Pain Index: Responsiveness and Testing of Criterion Validity
inferredcites →https://doi.org/10.1111/jvim.12312openalex-snapshot
Detection of Clinically Relevant Pain Relief in Cats with Degenerative Joint Disease Associated Pain
inferredcites →https://doi.org/10.1111/jvim.13985openalex-snapshot
In Vitro and In Vivo Characterization of a Fully Felinized Therapeutic Anti-Nerve Growth Factor Monoclonal Antibody for the Treatment of Pain in Cats
inferredcites →https://doi.org/10.1177/1098612x13511446openalex-snapshot
Prevalence and classification of chronic kidney disease in cats randomly selected from four age groups and in cats recruited for degenerative joint disease studies
inferredcites →https://doi.org/10.1177/1098612x14539499openalex-snapshot
Clinical trials involving cats
inferredcites →https://doi.org/10.1186/1746-6148-8-10openalex-snapshot
Relationship of orthopedic examination, goniometric measurements, and radiographic signs of degenerative joint disease in cats
inferredcites →https://doi.org/10.1186/s12917-015-0413-xopenalex-snapshot
A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain
inferredcites →https://doi.org/10.1371/journal.pone.0131839openalex-snapshot
Criterion Validation Testing of Clinical Metrology Instruments for Measuring Degenerative Joint Disease Associated Mobility Impairment in Cats
inferredcites →https://doi.org/10.2460/ajvr.71.12.1417openalex-snapshot
Item generation and design testing of a questionnaire to assess degenerative joint disease–associated pain in cats
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4683653openalex-extracted
Translation, Cross-Cultural Adaptation and Validation of the Feline Musculoskeletal Pain Screening Checklist into Brazilian Portuguese
inferred← citeshttps://doi.org/10.2139/ssrn.4683654openalex-extracted
Translation, Cross-Cultural Adaptation and Validation of the Feline Musculoskeletal Pain Screening Checklist into Brazilian Portuguese
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Treatment of Chronic (Maladaptive) Pain
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Skin and Musculoskeletal Diseases
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Appendix 2: Medications for Pain Management in CatsElizabeth Stelow
inferred← citeshttps://doi.org/10.1002/9781119830306.ch48openalex-snapshot
Clinical Management and Pharmacologic Treatment of Pain
inferred← citeshttps://doi.org/10.1002/vetr.516openalex-snapshot
Defining the rate of, and factors influencing, radiographic progression of osteoarthritis of the canine hip joint
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Analysis of serum biomarkers associated with pain in Spanish greyhounds undergoing ovariohysterectomy
inferred← citeshttps://doi.org/10.1007/5584_2022_717openalex-snapshot
Articular Cartilage Regeneration in Veterinary Medicine
inferred← citeshttps://doi.org/10.1016/b978-0-323-49687-2.00006-0openalex-snapshot
Assessment and Management of Pain
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Supportive Care for the Cancer Patient
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Pathophysiology and Treatment of Osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.applanim.2017.11.013openalex-snapshot
Development and preliminary validity and reliability of the montreal instrument for cat arthritis testing, for use by caretaker/owner, MI-CAT(C), via a randomised clinical trial
inferred← citeshttps://doi.org/10.1016/j.cvsm.2020.02.003openalex-snapshot
Feline Chronic Pain and Osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.jneumeth.2020.108997openalex-snapshot
Animal models of pain: Diversity and benefits
inferred← citeshttps://doi.org/10.1016/j.joca.2017.11.011openalex-snapshot
Spontaneous painful disease in companion animals can facilitate the development of chronic pain therapies for humans
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2020.107553openalex-snapshot
Targeting neurotrophic factors: Novel approaches to musculoskeletal pain
inferred← citeshttps://doi.org/10.1016/j.tvjl.2017.08.006openalex-snapshot
Chronic maladaptive pain in cats: A review of current and future drug treatment options
inferred← citeshttps://doi.org/10.1016/j.tvjl.2018.11.008openalex-snapshot
Characterization of gene expression in naturally occurring feline degenerative joint disease-associated pain
inferred← citeshttps://doi.org/10.1016/j.tvjl.2019.07.001openalex-snapshot
Measurement of chronic pain in companion animals: Discussions from the Pain in Animals Workshop (PAW) 2017
inferred← citeshttps://doi.org/10.1016/j.tvjl.2026.106909openalex-snapshot
Efficacy and safety of relfovetmab administered every three months for the treatment of pain associated with osteoarthritis in client-owned cats
inferred← citeshttps://doi.org/10.1016/j.vetimm.2026.111206openalex-snapshot
Pharmacokinetics and safety of an engineered anti-feline PD-1 chimeric antibody following repeated intravenous and subcutaneous administration in healthy cats
inferred← citeshttps://doi.org/10.1016/s1283-0828(21)45663-2openalex-snapshot
10.1016/s1283-0828(21)45663-2
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10.1016/s1283-0828(21)45922-3
inferred← citeshttps://doi.org/10.1021/acsptsci.5c00706openalex-snapshot
Overview of the Current Osteoarthritis Treatment in Veterinary Medicine and Future Directions
inferred← citeshttps://doi.org/10.1038/s41598-021-87023-2openalex-snapshot
Robenacoxib shows efficacy for the treatment of chronic degenerative joint disease-associated pain in cats: a randomized and blinded pilot clinical trial
inferred← citeshttps://doi.org/10.1038/s41598-021-87304-wopenalex-snapshot
Novel approach to modeling high-frequency activity data to assess therapeutic effects of analgesics in chronic pain conditions
inferred← citeshttps://doi.org/10.1055/s-0044-1788038openalex-snapshot
Activity Levels in Seven Cats with Osteoarthritis Monitored by GPS Tracker Following Frunevetmab Injection
inferred← citeshttps://doi.org/10.1093/jvimsj/aalag003openalex-snapshot
Safety assessment of frunevetmab for osteoarthritis pain in cats: disproportionality analysis of the Food and Drug Administration Animal Drug Adverse Events database
inferred← citeshttps://doi.org/10.1093/stmcls/sxae034openalex-snapshot
Evaluation of stem-cell therapies in companion animal disease models: a concise review (2015-2023)
inferred← citeshttps://doi.org/10.1097/bor.0000000000000354openalex-snapshot
Nerve growth factor blockade for the management of osteoarthritis pain: what can we learn from clinical trials and preclinical models?
inferred← citeshttps://doi.org/10.1097/j.pain.0000000000000799openalex-snapshot
Anti–nerve growth factor therapy increases spontaneous day/night activity in mice with orthopedic surgery–induced pain
inferred← citeshttps://doi.org/10.1097/j.pain.0000000000000978openalex-snapshot
Translational pain assessment: could natural animal models be the missing link?
inferred← citeshttps://doi.org/10.1111/jsap.13566openalex-snapshot
2022 WSAVA guidelines for the recognition, assessment and treatment of pain
inferred← citeshttps://doi.org/10.1111/jvim.15313openalex-snapshot
The pharmacokinetics of gabapentin in cats
inferred← citeshttps://doi.org/10.1111/jvim.16291openalex-snapshot
Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats
inferred← citeshttps://doi.org/10.1111/vsu.13822openalex-snapshot
Long‐term follow up of 44 cats undergoing total hip replacement: Cases from a feline hip registry (2010‐2020)
inferred← citeshttps://doi.org/10.1136/vr.104168openalex-snapshot
Caregiver placebo effect in analgesic clinical trials for cats with naturally occurring degenerative joint disease‐associated pain
inferred← citeshttps://doi.org/10.1136/vr.104590openalex-snapshot
Anti‐nerve growth factor monoclonal antibodies for the control of pain in dogs and cats
inferred← citeshttps://doi.org/10.1136/vr.k5292openalex-snapshot
Anti‐nerve growth factor monoclonal antibody: a prospective new therapy for canine and feline osteoarthritis
inferred← citeshttps://doi.org/10.1177/1098612x17730172openalex-snapshot
Refinement of the Montreal Instrument for Cat Arthritis Testing, for Use by Veterinarians: detection of naturally occurring osteoarthritis in laboratory cats
inferred← citeshttps://doi.org/10.1177/1098612x18787910openalex-snapshot
Prescribing practices of veterinarians in the treatment of chronic musculoskeletal pain in cats
inferred← citeshttps://doi.org/10.1177/1098612x19856179openalex-snapshot
Chronic pain in cats: Recent advances in clinical assessment
inferred← citeshttps://doi.org/10.1177/1098612x20907424openalex-snapshot
Development of a checklist for the detection of degenerative joint disease-associated pain in cats
inferred← citeshttps://doi.org/10.1177/1098612x20965832openalex-snapshot
Feline musculoskeletal ageing: How are we diagnosing and treating musculoskeletal impairment?
inferred← citeshttps://doi.org/10.1177/1098612x20967639openalex-snapshot
Owner evaluation of quality of life and mobility in osteoarthritic cats treated with amantadine or placebo
inferred← citeshttps://doi.org/10.1177/1098612x211011984openalex-snapshot
Refinement of the Feline Musculoskeletal Pain Index (FMPI) and development of the short-form FMPI
inferred← citeshttps://doi.org/10.1177/1098612x211021538openalex-snapshot
2021 AAFP Feline Senior Care Guidelines
inferred← citeshttps://doi.org/10.1177/1098612x211053484openalex-snapshot
Evaluation of a nutritional supplement for the alleviation of pain associated with feline degenerative joint disease: a prospective, randomized, stratified, double-blind, placebo-controlled clinical trial
inferred← citeshttps://doi.org/10.1177/1098612x231178765openalex-snapshot
Do owner-reported changes in mobility reflect measures of activity, pain and degenerative joint disease in cats?
inferred← citeshttps://doi.org/10.1177/1098612x231198416openalex-snapshot
Cutaneous lesions and clinical outcomes in five cats after frunevetmab injections
inferred← citeshttps://doi.org/10.1177/1098612x241241951openalex-snapshot
2024 ISFM and AAFP consensus guidelines on the long-term use of NSAIDs in cats
inferred← citeshttps://doi.org/10.1177/1098612x251347999openalex-snapshot
Osteoarthritis in cats: what we know, and mostly, what we don’t know. . . yet
inferred← citeshttps://doi.org/10.1177/1098612x251380011openalex-snapshot
Clinical therapeutics in feline medicine: updates for old and new drugs
inferred← citeshttps://doi.org/10.1186/s12917-017-1151-zopenalex-snapshot
A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models
inferred← citeshttps://doi.org/10.1186/s40813-025-00421-0openalex-snapshot
Part I: understanding pain in pigs—basic knowledge about pain assessment, measures and therapy
inferred← citeshttps://doi.org/10.12968/coan.2021.0036openalex-snapshot
Understanding and managing pain in the arthritic synovial joint: an update
inferred← citeshttps://doi.org/10.1371/journal.pone.0169576openalex-snapshot
The Use of Functional Data Analysis to Evaluate Activity in a Spontaneous Model of Degenerative Joint Disease Associated Pain in Cats
inferred← citeshttps://doi.org/10.18849/ve.v8i4.623openalex-snapshot
The effect of anti-nerve growth factor monoclonal antibodies on the clinical signs of degenerative joint disease in cats
inferred← citeshttps://doi.org/10.2139/ssrn.5390647openalex-snapshot
The Impact of Bedinvetmab, a Canine Anti-Nerve Growth Factor Monoclonal Antibody, on Daily Activity Levels and Body Composition in Obese Dogs with Osteoarthritis
inferred← citeshttps://doi.org/10.2460/ajvr.81.4.334openalex-snapshot
Novel use of an activity monitor to model jumping behaviors in cats
inferred← citeshttps://doi.org/10.3166/dea-2019-0070openalex-snapshot
Projets douleur en médecine vétérinaire
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Proteomic profiling of serum in cats with naturally occurring degenerative joint disease and co-morbid conditions
inferred← citeshttps://doi.org/10.3389/fpain.2026.1716651openalex-snapshot
Artemin/GFRA3 axis and TRP channels: molecular insights from a feline model of osteoarthritis
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Neuro-sensitization in cats with chronic pain and its association to osteoarthritis progression
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Anti-NGF treatment worsens subchondral bone and cartilage measures while improving symptoms in floor-housed rabbits with osteoarthritis
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Prospective Evaluation of Feline Sourced Platelet-Rich Plasma Using Centrifuge-Based Systems
inferred← citeshttps://doi.org/10.3389/fvets.2021.610028openalex-snapshot
Efficacy and Safety of an Anti-nerve Growth Factor Antibody (Frunevetmab) for the Treatment of Degenerative Joint Disease-Associated Chronic Pain in Cats: A Multisite Pilot Field Study
inferred← citeshttps://doi.org/10.3389/fvets.2021.687448openalex-snapshot
Pharmacokinetics and Immunogenicity of Frunevetmab in Osteoarthritic Cats Following Intravenous and Subcutaneous Administration
inferred← citeshttps://doi.org/10.3389/fvets.2025.1502218openalex-snapshot
A randomised, parallel-group clinical trial comparing bedinvetmab to meloxicam for the management of canine osteoarthritis
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Physical Activity Monitors in Companion Animal Chronic Pain Research—A Review Focused on Osteoarthritis Pain
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Beyond Osteoarthritis: Emerging Applications of Anti-NGF Monoclonal Antibodies in Pain Management in Dogs and Cats
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Spinal Reactive Oxygen Species and Oxidative Damage Mediate Chronic Pain in Lame Dairy Cows
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2022 AAHA Pain Management Guidelines for Dogs and Cats*
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