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Not a barrier but a key: How bacteriophages exploit host's O‐antigen as an essential receptor to initiate infection

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-1-4614-0980-9_5openalex-snapshot
Contractile Tail Machines of Bacteriophages
inferredcites →https://doi.org/10.1007/978-1-4614-0980-9_7openalex-snapshot
Short Noncontractile Tail Machines: Adsorption and DNA Delivery by Podoviruses
inferredcites →https://doi.org/10.1007/s00253-015-7247-0openalex-snapshot
Bacteriophage-encoded depolymerases: their diversity and biotechnological applications
inferredcites →https://doi.org/10.1007/s00705-012-1383-yopenalex-snapshot
Prokaryote viruses studied by electron microscopy
inferredcites →https://doi.org/10.1007/s00705-015-2609-6openalex-snapshot
Taxonomic reassessment of N4-like viruses using comparative genomics and proteomics suggests a new subfamily - “Enquartavirinae”
inferredcites →https://doi.org/10.1016/j.virol.2012.01.027openalex-snapshot
Isolation and characterization of a novel indigenous intestinal N4-related coliphage vB_EcoP_G7C
inferredcites →https://doi.org/10.1016/j.virol.2014.11.002openalex-snapshot
Structure and biochemical characterization of bacteriophage phi92 endosialidase
inferredcites →https://doi.org/10.1016/j.virol.2015.02.010openalex-snapshot
Bacteriophage lambda: Early pioneer and still relevant
inferredcites →https://doi.org/10.1016/j.virol.2015.07.006openalex-snapshot
Bacteriophage P22 ejects all of its internal proteins before its genome
inferredcites →https://doi.org/10.1016/j.virol.2015.09.022openalex-snapshot
The T7 ejection nanomachine components gp15–gp16 form a spiral ring complex that binds DNA and a lipid membrane
inferredcites →https://doi.org/10.1016/s0378-1097(98)00061-5openalex-snapshot
General transducing phages like Salmonella phage P22 isolated using a smooth strain of Escherichia coli as host
inferredcites →https://doi.org/10.1038/nature17971openalex-snapshot
Structure of the T4 baseplate and its function in triggering sheath contraction
inferredcites →https://doi.org/10.1038/nsmb874openalex-snapshot
Crystal structure of the polysialic acid–degrading endosialidase of bacteriophage K1F
inferredcites →https://doi.org/10.1073/pnas.1501064112openalex-snapshot
Structural remodeling of bacteriophage T4 and host membranes during infection initiation
inferredcites →https://doi.org/10.1074/jbc.m110.169003openalex-snapshot
Tailspike Interactions with Lipopolysaccharide Effect DNA Ejection from Phage P22 Particles in Vitro
inferredcites →https://doi.org/10.1074/jbc.m114.614222openalex-snapshot
Conformational Changes Leading to T7 DNA Delivery upon Interaction with the Bacterial Receptor
inferredcites →https://doi.org/10.1074/jbc.m205294200openalex-snapshot
The Tailspike Protein of Shigella Phage Sf6
inferredcites →https://doi.org/10.1107/s1399004714002685openalex-snapshot
Bacteriophage P22 tailspike: structure of the complete protein and function of the interdomain linker
inferredcites →https://doi.org/10.1111/j.1365-2958.2008.06311.xopenalex-snapshot
Crystal structure of Escherichia coli phage HK620 tailspike: podoviral tailspike endoglycosidase modules are evolutionarily related
inferredcites →https://doi.org/10.1111/j.1365-2958.2012.08006.xopenalex-snapshot
Tail morphology controls DNA release in two Salmonella phages with one lipopolysaccharide receptor recognition system
inferredcites →https://doi.org/10.1111/mmi.12134openalex-snapshot
Long tail fibres of the novel broad‐host‐range T ‐even bacteriophage S 16 specifically recognize S almonella OmpC
inferredcites →https://doi.org/10.1111/mmi.12536openalex-snapshot
OmpA and OmpC are critical host factors for bacteriophage S f6 entry in S higella
inferredcites →https://doi.org/10.1111/mmi.13710openalex-snapshot
Function of bacteriophage G7C esterase tailspike in host cell adsorption
inferredcites →https://doi.org/10.1126/science.1231887openalex-snapshot
The Bacteriophage T7 Virion Undergoes Extensive Structural Remodeling During Infection
inferredcites →https://doi.org/10.1126/science.8023158openalex-snapshot
Crystal Structure of P22 Tailspike Protein: Interdigitated Subunits in a Thermostable Trimer
inferredcites →https://doi.org/10.1128/jb.02398-14openalex-snapshot
Variations in O-Antigen Biosynthesis and O-Acetylation Associated with Altered Phage Sensitivity in Escherichia coli 4s
inferredcites →https://doi.org/10.1128/jvi.01641-07openalex-snapshot
Structure of the Receptor-Binding Protein of Bacteriophage Det7: a Podoviral Tail Spike in a Myovirus
inferredcites →https://doi.org/10.1128/jvi.38.3.1025-1033.1981openalex-snapshot
Salmonella Bacteriophage Glycanases: Endorhamnosidase Activity of Bacteriophages P27, 9NA, and KB1
inferredcites →https://doi.org/10.1128/mbio.01152-16openalex-snapshot
Localization of the Houdinisome (Ejection Proteins) inside the Bacteriophage P22 Virion by Bubblegram Imaging
inferredcites →https://doi.org/10.1177/09680519050110030201openalex-snapshot
Review: Lipopolysaccharide inner core oligosaccharide structure and outer membrane stability in human pathogens belonging to the Enterobacteriaceae
inferredcites →https://doi.org/10.1179/096805105x46592openalex-snapshot
Lipopolysaccharide inner core oligosaccharide structure and outer membrane stability in human pathogens belonging to the Enterobacteriaceae

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4766460openalex-extracted
Role of Core Lipopolysaccharide Biosynthetic Genes in the Infection and Adsorption of Broad-Host-Range Bacteriophages of Rhizobium Etli
inferred← citeshttps://doi.org/10.1002/1873-3468.70383openalex-snapshot
Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions
inferred← citeshttps://doi.org/10.1002/chem.202000495openalex-snapshot
Increasing the Affinity of an O‐Antigen Polysaccharide Binding Site in Shigella flexneri Bacteriophage Sf6 Tailspike Protein
inferred← citeshttps://doi.org/10.1007/s00705-019-04371-1openalex-snapshot
The O-polysaccharide of Escherichia coli F5, which is structurally related to that of E. coli O28ab, provides cells only weak protection against bacteriophage attack
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The histidine crossroad: An integrative theory of the gut–liver–vascular axis in MASLD
inferred← citeshttps://doi.org/10.1016/j.copbio.2021.02.006openalex-snapshot
Reprogramming bacteriophage host range: design principles and strategies for engineering receptor binding proteins
inferred← citeshttps://doi.org/10.1016/j.csbj.2021.06.001openalex-snapshot
Structural and functional characterization of the receptor binding proteins of Escherichia coli O157 phages EP75 and EP335
inferred← citeshttps://doi.org/10.1016/j.fm.2020.103586openalex-snapshot
Development of a broad-spectrum Salmonella phage cocktail containing Viunalike and Jerseylike viruses isolated from Thailand
inferred← citeshttps://doi.org/10.1016/j.foodres.2023.113257openalex-snapshot
Evaluation of the biocontrol potential of a collagen peptide/trehalose-based Cronobacter sakazakii phage powder in rehydrated powdered infant formula
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The branched receptor-binding complex of Ackermannviridae phages promotes adaptive host recognition
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.100286openalex-snapshot
Pantoea stewartii WceF is a glycan biofilm-modifying enzyme with a bacteriophage tailspike-like fold
inferred← citeshttps://doi.org/10.1016/j.mib.2022.102225openalex-snapshot
Toothpicks, logic, and next-generation sequencing: systematic investigation of bacteriophage-host interactions
inferred← citeshttps://doi.org/10.1016/j.mib.2024.102471openalex-snapshot
Virulence-associated factors as targets for phage infection
inferred← citeshttps://doi.org/10.1016/j.micres.2024.127766openalex-snapshot
Role of core lipopolysaccharide biosynthetic genes in the infection and adsorption of broad-host-range bacteriophages of Rhizobium etli.
inferred← citeshttps://doi.org/10.1016/j.str.2025.11.012openalex-snapshot
Cryo-EM structure of cyanopodophage Pan3 reveals a modular tail architecture for host recognition
inferred← citeshttps://doi.org/10.1021/acs.chemrev.0c01321openalex-snapshot
A Journey from Structure to Function of Bacterial Lipopolysaccharides
inferred← citeshttps://doi.org/10.1021/jacs.8b03719openalex-snapshot
Solvent Networks Tune Thermodynamics of Oligosaccharide Complex Formation in an Extended Protein Binding Site
inferred← citeshttps://doi.org/10.1038/s41396-020-0628-0openalex-snapshot
Diversity and evolution of surface polysaccharide synthesis loci in Enterobacteriales
inferred← citeshttps://doi.org/10.1038/s41396-021-00921-1openalex-snapshot
Systematic discovery of pseudomonad genetic factors involved in sensitivity to tailocins
inferred← citeshttps://doi.org/10.1038/s41598-018-29983-6openalex-snapshot
Characterization of LE3 and LE4, the only lytic phages known to infect the spirochete Leptospira
inferred← citeshttps://doi.org/10.1038/s41598-019-39590-8openalex-snapshot
High-throughput LPS profiling as a tool for revealing of bacteriophage infection strategies
inferred← citeshttps://doi.org/10.1038/s41598-024-77463-xopenalex-snapshot
Isolation, characterization, and receptor-binding protein specificity of phages PAS7, PAS59 and PAS61 infecting Shiga toxin-producing Escherichia coli O103 and O146
inferred← citeshttps://doi.org/10.1039/d6an00499gopenalex-snapshot
Adsorption-stage phage biosensors for foodborne bacteria detection: mechanisms, engineering strategies, and perspectives
inferred← citeshttps://doi.org/10.1073/pnas.1919888117openalex-snapshot
Pleiotropy complicates a trade-off between phage resistance and antibiotic resistance
inferred← citeshttps://doi.org/10.1074/jbc.ra119.008133openalex-snapshot
Time-resolved DNA release from an O-antigen–specific Salmonella bacteriophage with a contractile tail
inferred← citeshttps://doi.org/10.1074/jbc.rev120.009402openalex-snapshot
Lipopolysaccharide O-antigens—bacterial glycans made to measure
inferred← citeshttps://doi.org/10.1093/ismeco/ycae101openalex-snapshot
Phage resistance mutations affecting the bacterial cell surface increase susceptibility to fungi in a model cheese community
inferred← citeshttps://doi.org/10.1093/molbev/msad154openalex-snapshot
Stepwise Evolution of E. coli C and ΦX174 Reveals Unexpected Lipopolysaccharide (LPS) Diversity
inferred← citeshttps://doi.org/10.1099/mic.0.001146openalex-snapshot
Diverse functions for acyltransferase-3 proteins in the modification of bacterial cell surfaces
inferred← citeshttps://doi.org/10.1101/2021.04.09.439263openalex-snapshot
Isolation and characterization of a novel bacteriophage, Kapi1, capable of O-antigen modification in commensal Escherichia coli
inferred← citeshttps://doi.org/10.1101/2021.09.20.461090openalex-snapshot
The E34 Phage Tailspike Protein: An in vitro characterization, Structure Prediction, Potential Interaction with S. newington LPS and Cytotoxicity Assessment to Animal Cell Line
inferred← citeshttps://doi.org/10.1101/2024.03.21.586117openalex-snapshot
The branched receptor binding complex of Ackermannviridae phages promotes adaptative host recognition
inferred← citeshttps://doi.org/10.1101/2024.08.19.608551openalex-snapshot
Bacteriophages inject DNA into giant unilamellar vesicles mimicking Gram-negative lipopolysaccharide outer membranes
inferred← citeshttps://doi.org/10.1111/1462-2920.15973openalex-snapshot
Bacteriophage S6 requires bacterial cellulose for Erwinia amylovora infection
inferred← citeshttps://doi.org/10.1111/mmi.13936openalex-snapshot
Genes affecting progression of bacteriophage P22 infection in Salmonella identified by transposon and single gene deletion screens
inferred← citeshttps://doi.org/10.1128/aem.00145-20openalex-snapshot
A Novel Tail-Associated O91-Specific Polysaccharide Depolymerase from a Podophage Reveals Lytic Efficacy of Shiga Toxin-Producing Escherichia coli
inferred← citeshttps://doi.org/10.1128/iai.00291-26openalex-snapshot
Bridging two kingdoms: binding interactions between enteric viruses and intestinal bacteria
inferred← citeshttps://doi.org/10.1128/iai.00926-19openalex-snapshot
Fitness Trade-Offs Resulting from Bacteriophage Resistance Potentiate Synergistic Antibacterial Strategies
inferred← citeshttps://doi.org/10.1128/jvi.00248-23openalex-snapshot
Structural Study of the Cobetia marina Bacteriophage 1 (Carin-1) by Cryo-EM
inferred← citeshttps://doi.org/10.1128/jvi.01584-22openalex-snapshot
Deciphering Bacteriophage T5 Host Recognition Mechanism and Infection Trigger
inferred← citeshttps://doi.org/10.1128/mbio.02085-21openalex-snapshot
Isolation and Characterization of a Novel Temperate Escherichia coli Bacteriophage, Kapi1, Which Modifies the O-Antigen and Contributes to the Competitiveness of Its Host during Colonization of the Murine Gastrointestinal Tract
inferred← citeshttps://doi.org/10.1128/mbio.03246-21openalex-snapshot
A New Sugar for an Old Phage: a c-di-GMP-Dependent Polysaccharide Pathway Sensitizes Escherichia coli for Bacteriophage Infection
inferred← citeshttps://doi.org/10.1128/mra.00270-25openalex-snapshot
Complete genome sequences of Escherichia coli phages Huey, Dewey, and Louie
inferred← citeshttps://doi.org/10.1128/msystems.01644-24openalex-snapshot
Phage DisCo: targeted discovery of bacteriophages by co-culture
inferred← citeshttps://doi.org/10.1128/spectrum.02049-23openalex-snapshot
Molecular and evolutionary basis of O-antigenic polysaccharide-driven phage sensitivity in environmental pseudomonads
inferred← citeshttps://doi.org/10.1128/spectrum.03911-22openalex-snapshot
Pseudomonas aeruginosa Resists Phage Infection via Eavesdropping on Indole Signaling
inferred← citeshttps://doi.org/10.1134/s0003683821040049openalex-snapshot
Role of Lipopolysaccharide and Nonspecific Porins of Yersinia pseudotuberculosis in the Reception of Pseudotuberculous Diagnostic Bacteriophage
inferred← citeshttps://doi.org/10.1134/s0006297917130053openalex-snapshot
Adsorption of bacteriophages on bacterial cells
inferred← citeshttps://doi.org/10.1134/s0026261719060067openalex-snapshot
T5 Group Bacteriophages as Potential Phage Therapy Agents
inferred← citeshttps://doi.org/10.1155/2021/7494144openalex-snapshot
The Analysis of OmpA and Rz/Rz1 of Lytic Bacteriophage from Surabaya, Indonesia
inferred← citeshttps://doi.org/10.1186/s12915-025-02445-yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1186/s12985-019-1269-7openalex-snapshot
Effect of a bacteriophage T5virus on growth of Shiga toxigenic Escherichia coli and Salmonella strains in individual and mixed cultures
inferred← citeshttps://doi.org/10.12688/f1000research.74169.1openalex-snapshot
Isolation and sequencing of three RB49-like bacteriophages infecting O antigen-producing E. coli strains
inferred← citeshttps://doi.org/10.1371/journal.pbio.3000877openalex-snapshot
High-throughput mapping of the phage resistance landscape in E. coli
inferred← citeshttps://doi.org/10.1371/journal.pbio.3001424openalex-snapshot
Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection
inferred← citeshttps://doi.org/10.1371/journal.pbio.3003063openalex-snapshot
Completing the BASEL phage collection to unlock hidden diversity for systematic exploration of phage–host interactions
inferred← citeshttps://doi.org/10.1371/journal.pbio.3003716openalex-snapshot
Capsular specificity in temperate phages of Klebsiella pneumoniae is driven by diverse receptor-binding enzymes
inferred← citeshttps://doi.org/10.1371/journal.pone.0215456openalex-snapshot
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inferred← citeshttps://doi.org/10.1371/journal.ppat.1014106openalex-snapshot
Role of the C-terminal modules of Klebsiella phage KP32 receptor-binding protein gp38 in protein and phage functionality
inferred← citeshttps://doi.org/10.15252/emmm.202012435openalex-snapshot
Biological foundations of successful bacteriophage therapy
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Characterization and comprehensive genome analysis of novel bacteriophage, vB_Kpn_ZCKp20p, with lytic and anti-biofilm potential against clinical multidrug-resistant Klebsiella pneumoniae
inferred← citeshttps://doi.org/10.3389/fmicb.2020.510638openalex-snapshot
In vitro Analysis of O-Antigen-Specific Bacteriophage P22 Inactivation by Salmonella Outer Membrane Vesicles
inferred← citeshttps://doi.org/10.3389/fmicb.2020.595697openalex-snapshot
Polar Flagella Glycosylation in Aeromonas: Genomic Characterization and Involvement of a Specific Glycosyltransferase (Fgi-1) in Heterogeneous Flagella Glycosylation
inferred← citeshttps://doi.org/10.3389/fmicb.2025.1588121openalex-snapshot
Escherichia coli Group 2 capsules and their interplay with bacteriophages
inferred← citeshttps://doi.org/10.3389/fmicb.2025.1621103openalex-snapshot
Phage therapy for environmental biotechnology applications
inferred← citeshttps://doi.org/10.3390/antibiotics10060671openalex-snapshot
Antimicrobials and Food-Related Stresses as Selective Factors for Antibiotic Resistance along the Farm to Fork Continuum
inferred← citeshttps://doi.org/10.3390/antibiotics11070915openalex-snapshot
Evolutionary Dynamics between Phages and Bacteria as a Possible Approach for Designing Effective Phage Therapies against Antibiotic-Resistant Bacteria
inferred← citeshttps://doi.org/10.3390/biomedicines12102291openalex-snapshot
Biofilm Prevention and Removal in Non-Target Pseudomonas Strain by Siphovirus-like Coliphage
inferred← citeshttps://doi.org/10.3390/ijms20194929openalex-snapshot
Pyruvate Substitutions on Glycoconjugates
inferred← citeshttps://doi.org/10.3390/ijms24119320openalex-snapshot
Insights into the Alcyoneusvirus Adsorption Complex
inferred← citeshttps://doi.org/10.3390/microorganisms9061115openalex-snapshot
Prophage Genomics and Ecology in the Family Rhodobacteraceae
inferred← citeshttps://doi.org/10.3390/microorganisms9091869openalex-snapshot
In Vitro and In Vivo Assessment of the Potential of Escherichia coli Phages to Treat Infections and Survive Gastric Conditions
inferred← citeshttps://doi.org/10.3390/microorganisms9112402openalex-snapshot
Gut Microbiota Parameters Potentially Useful in Clinical Perspective
inferred← citeshttps://doi.org/10.3390/v10040158openalex-snapshot
1st German Phage Symposium—Conference Report
inferred← citeshttps://doi.org/10.3390/v10060289openalex-snapshot
In Vitro Studies of Lipopolysaccharide-Mediated DNA Release of Podovirus HK620
inferred← citeshttps://doi.org/10.3390/v10080396openalex-snapshot
Enzymes and Mechanisms Employed by Tailed Bacteriophages to Breach the Bacterial Cell Barriers
inferred← citeshttps://doi.org/10.3390/v10080431openalex-snapshot
Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens
inferred← citeshttps://doi.org/10.3390/v11060520openalex-snapshot
Characterization of Flagellotropic, Chi-Like Salmonella Phages Isolated from Thai Poultry Farms
inferred← citeshttps://doi.org/10.3390/v13030478openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/v15020286openalex-snapshot
Tailoring the Host Range of Ackermannviridae Bacteriophages through Chimeric Tailspike Proteins
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Interactions of Bacterial Extracellular Vesicles with Bacteriophages: Minireview
inferred← citeshttps://doi.org/10.70675/3085a957zab32z4127z9325z0ea892f33c81openalex-snapshot
Biocontrôle de la colibacillose aviaire par les bactériophages
inferred← citeshttps://doi.org/10.70675/6a16452bzebb1z4de2zbde8zc54cd26f1292openalex-snapshot
Rôle des phages dans l'évolution des leptospires
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