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Passive stiffness of fibrotic skeletal muscle in mdx mice relates to collagen architecture

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Relationships between range of motion, Lo, and passive force in five strap-like muscles of the feline hind limb
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Strain stiffening in collagen I networks
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Fabrication of skeletal muscle constructs by topographic activation of cell alignment
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Liver Stiffness Identifies Two Different Patterns of Fibrosis Progression in Patients With Hepatitis C Virus Recurrence After Liver Transplantation
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Effect of fiber distribution and realignment on the nonlinear and inhomogeneous mechanical properties of human supraspinatus tendon under longitudinal tensile loading
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Systemic administration of L ‐arginine benefits mdx skeletal muscle function
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Structure and function of the skeletal muscle extracellular matrix
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Protective effect of female gender–related factors on muscle force‐generating capacity and fragility in the dystrophic mdx mouse
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Increased collagen cross‐linking is a signature of dystrophin‐deficient muscle
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Conference report on contractures in musculoskeletal and neurological conditions
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Extraocular, limb and diaphragm muscle group-specific antioxidant enzyme activity patterns in control and mdx mice
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Dystrophin: The protein product of the duchenne muscular dystrophy locus
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Animal Models of Muscular Dystrophy
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Long-Range Force Transmission in Fibrous Matrices Enabled by Tension-Driven Alignment of Fibers
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Passive mechanical properties of the lumbar multifidus muscle support its role as a stabilizer
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Passive nonlinear elastic behaviour of skeletal muscle: Experimental results and model formulation
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Collagen crosslinking does not dictate stiffness in a transgenic mouse model of skeletal muscle fibrosis
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Regulation of fibrosis in muscular dystrophy
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Genetic background influences muscular dystrophy
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Prevention and Management of Limb Contractures in Neuromuscular Diseases
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Pathophysiology of Muscle Contractures in Cerebral Palsy
inferredcites →https://doi.org/10.1016/j.stem.2015.11.005openalex-snapshot
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Limb Contractures in Progressive Neuromuscular Disease and the Role of Stretching, Orthotics, and Surgery
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inferredcites →https://doi.org/10.1038/cddis.2015.198openalex-snapshot
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Single-cell transcriptional profiles in human skeletal muscle
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The scanning gradient Fourier transform (SGFT) method for assessing sarcomere organization and alignment
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Contribution of extracellular matrix components to the stiffness of skeletal muscle contractures in patients with cerebral palsy
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Myotubes differentiate optimally on substrates with tissue-like stiffness
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PAI-1–regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy
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Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling
inferredcites →https://doi.org/10.1093/hmg/ddt627openalex-snapshot
Recessive and dominant mutations in COL12A1 cause a novel EDS/myopathy overlap syndrome in humans and mice
inferredcites →https://doi.org/10.1096/fj.201802488ropenalex-snapshot
Natural disease history of the D2‐mdx mouse model for Duchenne muscular dystrophy
inferredcites →https://doi.org/10.1111/acel.12578openalex-snapshot
Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion
inferredcites →https://doi.org/10.1111/j.1600-0838.1997.tb00139.xopenalex-snapshot
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Principles and standards for reporting animal experiments in The Journal of Physiology and Experimental Physiology
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New perspectives on the development of muscle contractures following central motor lesions
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High resolution three‐dimensional reconstruction of fibrotic skeletal muscle extracellular matrix
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Infiltration of intramuscular adipose tissue impairs skeletal muscle contraction
inferredcites →https://doi.org/10.1113/jphysiol.2010.201921openalex-snapshot
Lateral transmission of force is impaired in skeletal muscles of dystrophic mice and very old rats
inferredcites →https://doi.org/10.1113/jphysiol.2010.203364openalex-snapshot
Hamstring contractures in children with spastic cerebral palsy result from a stiffer extracellular matrix and increased in vivo sarcomere length
inferredcites →https://doi.org/10.1115/1.1504099openalex-snapshot
Confined Compression of a Tissue-Equivalent: Collagen Fibril and Cell Alignment in Response to Anisotropic Strain
inferredcites →https://doi.org/10.1115/1.2834292openalex-snapshot
The Influence of Strain Rate on the Passive and Stimulated Engineering Stress–Large Strain Behavior of the Rabbit Tibialis Anterior Muscle
inferredcites →https://doi.org/10.1115/1.4004993openalex-snapshot
A Nonlinear Model of Passive Muscle Viscosity
inferredcites →https://doi.org/10.1115/1.4026285openalex-snapshot
Analysis of Collagen Organization in Mouse Achilles Tendon Using High-Frequency Ultrasound Imaging
inferredcites →https://doi.org/10.1117/1.jbo.18.2.026005openalex-snapshot
Quantitative evaluation of skeletal muscle defects in second harmonic generation images
inferredcites →https://doi.org/10.1126/science.1191035openalex-snapshot
Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture
inferredcites →https://doi.org/10.1126/science.1240104openalex-snapshot
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
inferredcites →https://doi.org/10.1126/scitranslmed.aao0475openalex-snapshot
Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials
inferredcites →https://doi.org/10.1152/ajpcell.00220.2012openalex-snapshot
Molecular, cellular, and muscle strip mechanics of the mdx mouse diaphragm
inferredcites →https://doi.org/10.1152/ajpcell.00253.2010openalex-snapshot
A muscle resident cell population promotes fibrosis in hindlimb skeletal muscles of mdx mice through the Wnt canonical pathway
inferredcites →https://doi.org/10.1152/ajpcell.00383.2013openalex-snapshot
Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice
inferredcites →https://doi.org/10.1152/ajpcell.1993.265.3.c834openalex-snapshot
Adaptations in myosin heavy chain expression and contractile function in dystrophic mouse diaphragm
inferredcites →https://doi.org/10.1152/ajpgi.00032.2007openalex-snapshot
Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis
inferredcites →https://doi.org/10.1152/ajpheart.01253.2007openalex-snapshot
Functional resolution of fibrosis in mdx mouse dystrophic heart and skeletal muscle by halofuginone
inferredcites →https://doi.org/10.1152/japplphysiol.00278.2018openalex-snapshot
Muscle contracture and passive mechanics in cerebral palsy
inferredcites →https://doi.org/10.1152/japplphysiol.00374.2013openalex-snapshot
Targeted inhibition of TGF-β results in an initial improvement but long-term deficit in force production after contraction-induced skeletal muscle injury
inferredcites →https://doi.org/10.1152/japplphysiol.00865.2018openalex-snapshot
Titin as a force-generating muscle protein under regulatory control
inferredcites →https://doi.org/10.1152/japplphysiol.01425.2010openalex-snapshot
The passive mechanical properties of the extensor digitorum longus muscle are compromised in 2- to 20-mo-old mdx mice
inferredcites →https://doi.org/10.1152/physiol.00026.2017openalex-snapshot
Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics
inferredcites →https://doi.org/10.1161/01.cir.96.6.1991openalex-snapshot
Myocardial Stiffness Is Attributed to Alterations in Cross-Linked Collagen Rather Than Total Collagen or Phenotypes in Spontaneously Hypertensive Rats
inferredcites →https://doi.org/10.1161/01.hyp.30.3.383openalex-snapshot
Contractile Systolic and Diastolic Dysfunction in Renin-Induced Hypertensive Cardiomyopathy
inferredcites →https://doi.org/10.1172/jci93561openalex-snapshot
Mechanosensing and fibrosis
inferredcites →https://doi.org/10.1186/2044-5040-1-21openalex-snapshot
Aberrant repair and fibrosis development in skeletal muscle
inferredcites →https://doi.org/10.1186/2044-5040-4-7openalex-snapshot
Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy
inferredcites →https://doi.org/10.1186/s12891-018-2212-6openalex-snapshot
Lower extremity joint contracture according to ambulatory status in children with Duchenne muscular dystrophy
inferredcites →https://doi.org/10.1242/jeb.182089openalex-snapshot
Frog muscle fibers bear a larger fraction of passive muscle tension than mouse fibers
inferredcites →https://doi.org/10.1242/jeb.204.9.1529openalex-snapshot
Sarcomere Length Operating Range of Vertebrate Muscles During Movement
inferredcites →https://doi.org/10.1364/boe.9.006350openalex-snapshot
Polarization-resolved second harmonic microscopy of skeletal muscle in sepsis
inferredcites →https://doi.org/10.1369/0022155417718541openalex-snapshot
Fluorescence of Picrosirius Red Multiplexed With Immunohistochemistry for the Quantitative Assessment of Collagen in Tissue Sections
inferredcites →https://doi.org/10.1371/journal.pone.0005902openalex-snapshot
Strain-Induced Alignment in Collagen Gels
inferredcites →https://doi.org/10.1371/journal.pone.0216537openalex-snapshot
Fiber alignment drives changes in architectural and mechanical features in collagen matrices
inferredcites →https://doi.org/10.1371/journal.pone.0224232openalex-snapshot
Fibre and extracellular matrix contributions to passive forces in human skeletal muscles: An experimental based constitutive law for numerical modelling of the passive element in the classical Hill-type three element model
inferredcites →https://doi.org/10.1529/biophysj.105.066944openalex-snapshot
Optical Clearing for Improved Contrast in Second Harmonic Generation Imaging of Skeletal Muscle
inferredcites →https://doi.org/10.1529/biophysj.105.071555openalex-snapshot
Characterization of the Myosin-Based Source for Second-Harmonic Generation from Muscle Sarcomeres
inferredcites →https://doi.org/10.2353/ajpath.2010.090887openalex-snapshot
Genetic Background Affects Properties of Satellite Cells and mdx Phenotypes
inferredcites →https://doi.org/10.3389/fbioe.2020.00203openalex-snapshot
Harnessing Fiber Diameter-Dependent Effects of Myoblasts Toward Biomimetic Scaffold-Based Skeletal Muscle Regeneration
inferredcites →https://doi.org/10.3389/fphys.2020.00211openalex-snapshot
Non-linear Scaling of Passive Mechanical Properties in Fibers, Bundles, Fascicles and Whole Rabbit Muscles
inferredcites →https://doi.org/10.3791/50036openalex-snapshot
Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies
inferredcites →https://doi.org/10.7554/elife.36354openalex-snapshot
Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis
inferredcites →https://doi.org/10.7554/elife.40532openalex-snapshot
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Complexity of skeletal muscle degeneration: multi-systems pathophysiology and organ crosstalk in dystrophinopathy
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Multiscale Passive Mechanical Characterization of Rodent Skeletal Muscle
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Along- and cross-muscle fiber shear moduli in skeletal muscle
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Passive mechanical properties of adipose tissue and skeletal muscle from C57BL/6J mice
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The extracellular matrix of dystrophic mouse diaphragm accounts for the majority of its passive stiffness and is resistant to collagenase digestion
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Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors
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Matrix stiffness and architecture drive fibro-adipogenic progenitors’ activation into myofibroblasts
inferred← citeshttps://doi.org/10.1038/s41598-023-37762-1openalex-snapshot
Specific and label-free endogenous signature of dystrophic muscle by Synchrotron deep ultraviolet radiation
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Combined stimuli of elasticity and microgrooves form aligned myotubes that characterize slow twitch muscles
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Histological characterization and quantification of late damage in mice after proton and photon irradiation
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Submaximal Eccentric Training During Immobilization Does Not Prevent Serial Sarcomere Loss or Impairments in Mechanical Function in Old or Young Rats
inferred← citeshttps://doi.org/10.1096/fj.202100711rropenalex-snapshot
A mutation in desmin makes skeletal muscle less vulnerable to acute muscle damage after eccentric loading in rats
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Collagen content and cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of collagen cross-linking inhibitor beta-aminopropionitrile
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Rapid histological quantification of muscle fibrosis and lysosomal activity using the HSB colour space
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Collagen architecture and biomechanics of gracilis and adductor longus muscles from children with cerebral palsy
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GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury
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Skeletal muscle progenitors are sensitive to collagen architectural features of fibril size and cross linking
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Thrown for a loop: fibro-adipogenic progenitors in skeletal muscle fibrosis
inferred← citeshttps://doi.org/10.1152/ajpcell.00287.2023openalex-snapshot
Alignment, cross linking, and beyond: a collagen architect’s guide to the skeletal muscle extracellular matrix
inferred← citeshttps://doi.org/10.1152/japplphysiol.00025.2022openalex-snapshot
Skeletal muscle properties show collagen organization and immune cell content are associated with resistance exercise response heterogeneity in older persons
inferred← citeshttps://doi.org/10.1152/japplphysiol.00041.2024openalex-snapshot
Age-related blunting of serial sarcomerogenesis and mechanical adaptations following 4 wk of maximal eccentric resistance training
inferred← citeshttps://doi.org/10.1152/japplphysiol.00248.2021openalex-snapshot
Diaphragm muscle fibrosis involves changes in collagen organization with mechanical implications in Duchenne muscular dystrophy
inferred← citeshttps://doi.org/10.1152/japplphysiol.00492.2025openalex-snapshot
Dystrophin deficiency stiffens skeletal muscle and impairs elasticity: an in vivo rheological examination
inferred← citeshttps://doi.org/10.1152/japplphysiol.00992.2025openalex-snapshot
Increasing intramuscular fluid volume increases passive tension in mammalian skeletal muscle
inferred← citeshttps://doi.org/10.1172/jci.insight.150112openalex-snapshot
Muscle fibrosis and maladaptation occur progressively in CKD and are rescued by dialysis
inferred← citeshttps://doi.org/10.1186/s13018-023-04069-wopenalex-snapshot
The pattern of collagen production may contribute to the gluteal muscle contracture pathogenic process
inferred← citeshttps://doi.org/10.1186/s13395-026-00432-7openalex-snapshot
Targeting muscle fibrosis using non-specific collagenase injections destabilizes the basal lamina and induces matrix remodeling
inferred← citeshttps://doi.org/10.1242/bio.059491openalex-snapshot
Influence of weighted downhill running training on serial sarcomere number and work loop performance in the rat soleus
inferred← citeshttps://doi.org/10.12688/wellcomeopenres.18251.1openalex-snapshot
The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy
inferred← citeshttps://doi.org/10.1371/journal.pone.0271776openalex-snapshot
Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor
inferred← citeshttps://doi.org/10.14814/phy2.71115openalex-snapshot
Long‐term imoxin treatment does not attenuate disease severity in dystrophic diaphragm of male mice
inferred← citeshttps://doi.org/10.1519/jsc.0000000000004898openalex-snapshot
Intramuscular Hamstring Stiffness Affects Anatomically Modeled Localized Muscle Strain During Passive Hip Flexion
inferred← citeshttps://doi.org/10.3389/fbioe.2024.1455225openalex-snapshot
ACL injury management: a comprehensive review of novel biotherapeutics
inferred← citeshttps://doi.org/10.3389/fendo.2022.801133openalex-snapshot
Evaluation of Muscle Mass and Stiffness with Limb Ultrasound in COVID-19 Survivors
inferred← citeshttps://doi.org/10.3389/fendo.2025.1560396openalex-snapshot
Hidden pathway: the role of extracellular matrix in type 2 diabetes mellitus–related sarcopenia
inferred← citeshttps://doi.org/10.3389/fphys.2021.804188openalex-snapshot
The Contributions of Extracellular Matrix and Sarcomere Properties to Passive Muscle Stiffness in Cerebral Palsy
inferred← citeshttps://doi.org/10.3389/fphys.2023.1183101openalex-snapshot
Duchenne muscular dystrophy: disease mechanism and therapeutic strategies
inferred← citeshttps://doi.org/10.3389/fspor.2024.1453730openalex-snapshot
Reliability of MyotonPro in measuring the biomechanical properties of the quadriceps femoris muscle in people with different levels and types of motor preparation
inferred← citeshttps://doi.org/10.3390/cancers18121928openalex-snapshot
Longitudinal Evaluation of Sternocleidomastoid Muscle Stiffness and Self-Reported Fibrosis-Related Symptoms After Radiotherapy in Patients with Head and Neck Cancer
inferred← citeshttps://doi.org/10.3390/ijms231810841openalex-snapshot
Myofibrillar Lattice Remodeling Is a Structural Cytoskeletal Predictor of Diaphragm Muscle Weakness in a Fibrotic mdx (mdx Cmah−/−) Model
inferred← citeshttps://doi.org/10.3390/life11080791openalex-snapshot
Skeletal Effects of Bone-Targeted TGFbeta Inhibition in a Mouse Model of Duchenne Muscular Dystrophy
inferred← citeshttps://doi.org/10.3390/life16010042openalex-snapshot
Relaxed Stiffness of Lower Extremity Muscles and Step Width Variability as Key Differences Between Sarcopenia and Dynapenia in Community-Dwelling Older Adults: A Cross-Sectional Study
inferred← citeshttps://doi.org/10.6084/m9.figshare.23902842openalex-snapshot
Additional file 1 of The pattern of collagen production may contribute to the gluteal muscle contracture pathogenic process
inferred← citeshttps://doi.org/10.70675/36243ce0zf732z454cz9b96z9e1df8ccce72openalex-snapshot
Deciphering the key conditions required to build a 3D biomimetic vascularized and innervated skeletal muscle-on-chip
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