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Exosome engineering for efficient and targeted drug delivery: Current status and future perspective

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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1007/s40199-026-00631-zopenalex-snapshot

Exosome-mediated siRNA delivery in cancer: Loading strategies, targeting approaches, and therapeutic outcomes

inferred← citeshttps://doi.org/10.1016/b978-0-443-22017-3.00005-6openalex-snapshot

Molecularly imprinted hydrogels in drug delivery

inferred← citeshttps://doi.org/10.1016/b978-0-443-23891-8.00011-1openalex-snapshot

Extracellular vesicles for ophthalmic and dermal ailments

inferred← citeshttps://doi.org/10.1016/b978-0-443-29052-7.00017-9openalex-snapshot

Current applications of new generations of exosomes nanovesicles

inferred← citeshttps://doi.org/10.1016/j.bbrep.2025.102313openalex-snapshot

Engineered mesenchymal stem cell-derived exosomes: A revolutionary approach to unlocking liver disease treatment

inferred← citeshttps://doi.org/10.1016/j.bioactmat.2024.02.021openalex-snapshot

Extracellular vesicles in nanomedicine and regenerative medicine: A review over the last decade

inferred← citeshttps://doi.org/10.1016/j.bioliv.2026.100003openalex-snapshot

Exosomes as emerging biomarkers and therapeutic platforms: From biology to clinical translation

inferred← citeshttps://doi.org/10.1016/j.expneurol.2024.114882openalex-snapshot

The role of exosomes derived from stem cells in nerve regeneration: A contribution to neurological repair

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e30630openalex-snapshot

Plant-derived exosome-like nanovesicles: A novel nanotool for disease therapy

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e34460openalex-snapshot

Mediation of radiation-induced bystander effect and epigenetic modification: The role of exosomes in cancer radioresistance

inferred← citeshttps://doi.org/10.1016/j.jlb.2024.100278openalex-snapshot

Global requirements for manufacturing and validation of clinical grade extracellular vesicles

inferred← citeshttps://doi.org/10.1016/j.jri.2023.103833openalex-snapshot

Exosome- based technologies as a platform for diagnosis and treatment of male and female infertility-related diseases

inferred← citeshttps://doi.org/10.1016/j.lfs.2025.123598openalex-snapshot

Exosomes in treating Eye Diseases: Targeting strategies

inferred← citeshttps://doi.org/10.1016/j.mtadv.2026.100950openalex-snapshot

Exosome trafficking, delivery, and detection, harnessed via 3D hydrogels and 3D DNA nanotechnologies

inferred← citeshttps://doi.org/10.1016/j.mtbio.2024.101312openalex-snapshot

Biodegradable exosome-engineered hydrogels for the prevention of peritoneal adhesions via anti-oxidation and anti-inflammation

inferred← citeshttps://doi.org/10.1016/j.mtbio.2025.101881openalex-snapshot

Engineering 3D-BMSC exosome-based hydrogels that collaboratively regulate bone microenvironment and promote osteogenesis for enhanced cell‐free bone regeneration

inferred← citeshttps://doi.org/10.1016/j.trac.2023.117310openalex-snapshot

Current progress and prospect of microfluidic-based exosome investigation

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.4c00952openalex-snapshot

Surface Engineered Osteoblast-Extracellular Vesicles Serve as an Efficient Carrier for Drug and Small RNA to Actively Target Osteosarcoma

inferred← citeshttps://doi.org/10.1021/acsnano.4c07992openalex-snapshot

Hybrid Nanoparticle Engineered with Transforming Growth Factor -β1-Overexpressed Extracellular Vesicle and Cartilage-Targeted Anti-Inflammatory Liposome for Osteoarthritis

inferred← citeshttps://doi.org/10.1080/15583724.2025.2561599openalex-snapshot

Exosomal Micro/Nanoparticles-Based Biological Polymersomes for Gene Delivery in Breast Cancer Therapy: Recent Advances and Progresses on Promising Approaches

inferred← citeshttps://doi.org/10.1080/17460751.2025.2561449openalex-snapshot

Stem cell-derived exosomes in wound healing: mechanistic insights and delivery strategies

inferred← citeshttps://doi.org/10.1080/21645515.2024.2345940openalex-snapshot

Exosome may be the next generation of promising cell-free vaccines

inferred← citeshttps://doi.org/10.1088/2632-959x/adff9fopenalex-snapshot

Bioinspired nanocarriers for advanced drug delivery

inferred← citeshttps://doi.org/10.1093/stcltm/szae027openalex-snapshot

Exploring the clinical transition of engineered exosomes designed for intracellular delivery of therapeutic proteins

inferred← citeshttps://doi.org/10.1111/bph.70403openalex-snapshot

Targeted peptide‐modified M2 exosomes drug delivery system for the targeted regulation of the lung injury microenvironment with isorhynchophylline (IRN): based on the inflammatory–metabolic–epigenetic synergy mechanism

inferred← citeshttps://doi.org/10.1111/cpr.13677openalex-snapshot

Exosomes on the development and progression of renal fibrosis

inferred← citeshttps://doi.org/10.1113/jp284018openalex-snapshot

The future of exosomes bioengineering in precision medicine

inferred← citeshttps://doi.org/10.1113/jp285654openalex-snapshot

Extracellular vesicles in organ and systems function in health and disease

inferred← citeshttps://doi.org/10.1134/s1819712423010087openalex-snapshot

Prospects for the Use of Small Extracellular Vesicles as a Transport Vehicle through the Blood–Brain Barrier

inferred← citeshttps://doi.org/10.1155/sci/4989846openalex-snapshot

The Evolving Role of Mesenchymal Stem Cells and Their Exosomes in Epilepsy Management: From Bench to Bedside

inferred← citeshttps://doi.org/10.1177/03000605251317476openalex-snapshot

Extracellular vesicles: their challenges and benefits as potential biomarkers for musculoskeletal disorders

inferred← citeshttps://doi.org/10.1186/s12951-023-01973-5openalex-snapshot

Extracellular vesicles: a rising star for therapeutics and drug delivery

inferred← citeshttps://doi.org/10.1186/s12951-025-03697-0openalex-snapshot

Engineered exosomes: a promising approach for overcoming challenges in pancreatic cancer therapy

inferred← citeshttps://doi.org/10.1186/s13287-025-04167-yopenalex-snapshot

Pyroptosis: candidate key targets for mesenchymal stem cell-derived exosomes for the treatment of bone-related diseases

inferred← citeshttps://doi.org/10.1302/2046-3758.1412.bjr-2025-0117.r1openalex-snapshot

The future of osteoarthritis treatment: exploring the potential of exosomes from adipose tissue-derived stem cells

inferred← citeshttps://doi.org/10.18632/oncotarget.28323openalex-snapshot

The future of bioorthogonal-chemistry for targeting of exosomes in precision medicine

inferred← citeshttps://doi.org/10.18687/laccei2023.1.1.1656openalex-snapshot

Research and development of emerging technologies for exosome-based cancer diagnostics and therapeutics

inferred← citeshttps://doi.org/10.2147/ijn.s476995openalex-snapshot

Exosomes Induce Crosstalk Between Multiple Types of Cells and Cardiac Fibroblasts: Therapeutic Potential for Remodeling After Myocardial Infarction

inferred← citeshttps://doi.org/10.2147/ijn.s547834openalex-snapshot

The New Approach to Treating Erectile Dysfunction: Stem Cell-Derived Extracellular Vesicles

inferred← citeshttps://doi.org/10.2174/0113816128338023241210140702openalex-snapshot

Metabolic Tagging Technology of Exosomes-An Updated Review

inferred← citeshttps://doi.org/10.2174/0113894501294136240610061328openalex-snapshot

Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges

inferred← citeshttps://doi.org/10.2174/0115733947341257241018150125openalex-snapshot

Disrupting Tumour Niches: Advanced Strategies for Targeting the Tumour Microenvironment in Cancer Therapy

inferred← citeshttps://doi.org/10.23937/2469-570x/1410079openalex-snapshot

Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer

inferred← citeshttps://doi.org/10.31857/s1027813323010089openalex-snapshot

Outlooks of Using Small Extracellular Vesicles as a Transport Vehicle through the Blood–Brain Barrier

inferred← citeshttps://doi.org/10.3389/fbioe.2026.1825617openalex-snapshot

Mammalian, plant, and gut microbiota-derived extracellular vesicles as emerging therapeutics for bone diseases

inferred← citeshttps://doi.org/10.3389/fcell.2024.1344705openalex-snapshot

Exosomes: a promising avenue for cancer diagnosis beyond treatment

inferred← citeshttps://doi.org/10.3389/fcell.2026.1854680openalex-snapshot

Exosomes: emerging biomarkers and therapeutic potential in postoperative delirium and postoperative cognitive dysfunction

inferred← citeshttps://doi.org/10.3389/fmedt.2025.1654003openalex-snapshot

Nanoparticles: a new frontier in neurodegenerative disease therapy

inferred← citeshttps://doi.org/10.3389/fphar.2026.1806328openalex-snapshot

Green tea–derived exosome-like nanoparticles attenuate oxidative stress–induced skin senescence via modulation of p38 MAPK signaling

inferred← citeshttps://doi.org/10.3390/bioengineering9110662openalex-snapshot

Mesenchymal Stem Cells and MSCs-Derived Extracellular Vesicles in Infectious Diseases: From Basic Research to Clinical Practice

inferred← citeshttps://doi.org/10.3390/cancers15041052openalex-snapshot

CAR-T-Derived Extracellular Vesicles: A Promising Development of CAR-T Anti-Tumor Therapy

inferred← citeshttps://doi.org/10.3390/cells11131989openalex-snapshot

Different Sourced Extracellular Vesicles and Their Potential Applications in Clinical Treatments

inferred← citeshttps://doi.org/10.3390/cells15010070openalex-snapshot

From CAR-T Cells to Exosome-Based Immunotherapy: Exploring the Frontiers of Cell-Free Targeted Cancer Therapeutics

inferred← citeshttps://doi.org/10.3390/cells15050422openalex-snapshot

Exosome Engineering for Blocking Gut Dysbiosis and Inducing Cell Death Mechanisms in Glioblastoma Multiforme

inferred← citeshttps://doi.org/10.3390/membranes12121244openalex-snapshot

Advances in Purification, Modification, and Application of Extracellular Vesicles for Novel Clinical Treatments

inferred← citeshttps://doi.org/10.3390/pharmaceutics14091919openalex-snapshot

“Targeting Design” of Nanoparticles in Tumor Therapy

inferred← citeshttps://doi.org/10.3390/pharmaceutics15020598openalex-snapshot

Exosome-Based Carrier for RNA Delivery: Progress and Challenges

inferred← citeshttps://doi.org/10.3390/pharmaceutics18060668openalex-snapshot

Exosomes as Disease-Informed Nanoplatforms for Pulmonary Fibrosis: From Pathogenic Signaling to Precision Diagnosis and Therapy

inferred← citeshttps://doi.org/10.3390/vaccines10101691openalex-snapshot

Regulation of Extracellular Vesicle-Mediated Immune Responses against Antigen-Specific Presentation

inferred← citeshttps://doi.org/10.4103/atn.atn-d-25-00001openalex-snapshot

Exosome-based therapy for spinal cord injury: a narrative review

inferred← citeshttps://doi.org/10.62347/kixf4662openalex-snapshot

Application of engineered exosomes in tumor therapy

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