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Rhodoxanthin synthase from honeysuckle; a membrane diiron enzyme catalyzes the multistep conversion of β-carotene to rhodoxanthin

https://doi.org/10.1126/sciadv.aay9226
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cber.19330660609openalex-snapshot
Über Rhodo‐xanthin, den Arillus‐Farbstoff der Eibe (Taxus baccata).
inferredcites →https://doi.org/10.1002/hlca.19700530513openalex-snapshot
New Methods for the Synthesis of Oxygenated Carotenoids
inferredcites →https://doi.org/10.1007/978-1-59745-289-2_12openalex-snapshot
Bimolecular Fluorescence Complementation (BiFC) to Study Protein-protein Interactions in Living Plant Cells
inferredcites →https://doi.org/10.1007/978-3-0348-7836-4openalex-snapshot
Carotenoids
inferredcites →https://doi.org/10.1007/s00438-005-0072-xopenalex-snapshot
Cloning of the astaxanthin synthase gene from Xanthophyllomyces dendrorhous (Phaffia rhodozyma) and its assignment as a β-carotene 3-hydroxylase/4-ketolase
inferredcites →https://doi.org/10.1016/0305-1978(87)90100-1openalex-snapshot
Different rhodoxanthin contents in the leaves of gymnosperms grown under various light intensities
inferredcites →https://doi.org/10.1016/b978-0-12-372180-8.50042-1openalex-snapshot
AMPLIFICATION AND DIRECT SEQUENCING OF FUNGAL RIBOSOMAL RNA GENES FOR PHYLOGENETICS
inferredcites →https://doi.org/10.1016/j.abb.2004.02.003openalex-snapshot
Progress in understanding the origin and functions of carotenoid hydroxylases in plants
inferredcites →https://doi.org/10.1016/j.abb.2013.09.009openalex-snapshot
Vibrational and electronic spectroscopy of the retro-carotenoid rhodoxanthin in avian plumage, solid-state films, and solution
inferredcites →https://doi.org/10.1016/j.cbpb.2007.02.004openalex-snapshot
Plumage carotenoids of the Pin-tailed Manakin (Ilicura militaris): Evidence for the endogenous production of rhodoxanthin from a colour variant
inferredcites →https://doi.org/10.1016/s0005-2760(98)00029-0openalex-snapshot
Xanthophyll biosynthesis: molecular and functional characterization of carotenoid hydroxylases from pepper fruits (Capsicum annuum L.)
inferredcites →https://doi.org/10.1016/s0021-9258(18)74131-8openalex-snapshot
ESCHSCHOLTZXANTHIN: A NEW XANTHOPHYLL FROM THE PETALS OF THE CALIFORNIA POPPY, ESCHSCHOLTZIA CALIFORNICA
inferredcites →https://doi.org/10.1016/s1369-5266(00)00163-1openalex-snapshot
Carotenoid biosynthesis in flowering plants
inferredcites →https://doi.org/10.1021/bi00209a009openalex-snapshot
Eight Histidine Residues Are Catalytically Essential in a Membrane-Associated Iron Enzyme, Stearoyl-CoA Desaturase, and Are Conserved in Alkane Hydroxylase and Xylene Monooxygenase
inferredcites →https://doi.org/10.1021/cr400106yopenalex-snapshot
Mechanistic Aspects of Carotenoid Biosynthesis
inferredcites →https://doi.org/10.1021/jacs.7b10033openalex-snapshot
Keto–Enol Tautomerization Triggers an Electrophilic Aldehyde Deformylation Reaction by a Nonheme Manganese(III)-Peroxo Complex
inferredcites →https://doi.org/10.1038/srep05627openalex-snapshot
Bird fruit preferences match the frequency of fruit colours in tropical Asia
inferredcites →https://doi.org/10.1073/pnas.0705385104openalex-snapshot
A multifunctional desaturase involved in the biosynthesis of the processionary moth sex pheromone
inferredcites →https://doi.org/10.1074/jbc.m115.680124openalex-snapshot
The Crystal Structure of an Integral Membrane Fatty Acid α-Hydroxylase
inferredcites →https://doi.org/10.1074/jbc.m200231200openalex-snapshot
Desaturation and Hydroxylation
inferredcites →https://doi.org/10.1074/jbc.m702520200openalex-snapshot
The Crystal Structure of the Ivy Δ4-16:0-ACP Desaturase Reveals Structural Details of the Oxidized Active Site and Potential Determinants of Regioselectivity
inferredcites →https://doi.org/10.1074/jbc.r900009200openalex-snapshot
Desaturases: Emerging Models for Understanding Functional Diversification of Diiron-containing Enzymes
inferredcites →https://doi.org/10.1074/jbc.ra118.005972openalex-snapshot
Two clusters of residues contribute to the activity and substrate specificity of Fm1, a bifunctional oleate and linoleate desaturase of fungal origin
inferredcites →https://doi.org/10.1074/mcp.ra117.000314openalex-snapshot
Optimization of Experimental Parameters in Data-Independent Mass Spectrometry Significantly Increases Depth and Reproducibility of Results
inferredcites →https://doi.org/10.1093/bioinformatics/btu153openalex-snapshot
Prokka: rapid prokaryotic genome annotation
inferredcites →https://doi.org/10.1093/jxb/err140openalex-snapshot
A proteomic analysis of the chromoplasts isolated from sweet orange fruits [Citrus sinensis (L.) Osbeck]
inferredcites →https://doi.org/10.1093/nar/gkh131openalex-snapshot
UniProt: the Universal Protein knowledgebase
inferredcites →https://doi.org/10.1093/nar/gkw1099openalex-snapshot
UniProt: the universal protein knowledgebase
inferredcites →https://doi.org/10.1101/gr.1917404openalex-snapshot
Using the miraEST Assembler for Reliable and Automated mRNA Transcript Assembly and SNP Detection in Sequenced ESTs
inferredcites →https://doi.org/10.1101/sqb.2013.77.014712openalex-snapshot
Color and Scent: How Single Genes Influence Pollinator Attraction
inferredcites →https://doi.org/10.1105/tpc.105.039966openalex-snapshot
A Chromoplast-Specific Carotenoid Biosynthesis Pathway Is Revealed by Cloning of the Tomato white-flower Locus
inferredcites →https://doi.org/10.1105/tpc.111.086827openalex-snapshot
Elucidation of the Pathway to Astaxanthin in the Flowers of Adonis aestivalis
inferredcites →https://doi.org/10.1109/gce.2010.5676129openalex-snapshot
Creating the CIPRES Science Gateway for inference of large phylogenetic trees
inferredcites →https://doi.org/10.1111/j.1751-1097.1991.tb01989.xopenalex-snapshot
CAROTENOIDS OF Erwinia herbicola AND AN Escherichia coli HB101 STRAIN CARRYING THE Erwinia herbicola CAROTENOID GENE CLUSTER
inferredcites →https://doi.org/10.1128/aem.02556-12openalex-snapshot
Heterologous Carotenoid-Biosynthetic Enzymes: Functional Complementation and Effects on Carotenoid Profiles in Escherichia coli
inferredcites →https://doi.org/10.1128/ec.00265-06openalex-snapshot
Carotenoid Biosynthesis in the Primitive Red Alga Cyanidioschyzon merolae
inferredcites →https://doi.org/10.1146/annurev.arplant.49.1.557openalex-snapshot
GENES AND ENZYMES OF CAROTENOID BIOSYNTHESIS IN PLANTS
inferredcites →https://doi.org/10.1146/annurev.arplant.49.1.611openalex-snapshot
DESATURATION AND RELATED MODIFICATIONS OF FATTY ACIDS
inferredcites →https://doi.org/10.1515/znc-1973-7-813openalex-snapshot
Ketocarotinoide in den Früchten von Lonicera webbiana und Lonicera ruprechtiana / Ketocarotinoids of the Berries from Lonicera webbiana and Lonicera ruprechtiana
inferredcites →https://doi.org/10.1525/auk.2012.11235openalex-snapshot
Rhodoxanthin as a characteristic keto-carotenoid of manakins (Pipridae)
inferredcites →https://doi.org/10.1676/11-161.1openalex-snapshot
Diet-Induced Plumage Erythrism in Baltimore Orioles as a Result of the Spread of Introduced Shrubs

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2021.112741zenodo-depositor-declared
Carotenoid profiles of red- and yellow-colored arils of cultivars of Taxus baccata L. and Taxus × media Rehder
inferred← citeshttps://doi.org/10.1002/1873-3468.14342openalex-snapshot
Promiscuous activity of β‐carotene hydroxylase CrtZ on epoxycarotenoids leads to the formation of rare carotenoids with 6‐hydroxy‐3‐keto‐ε‐ends
inferred← citeshttps://doi.org/10.1002/rcm.9250openalex-snapshot
Atmospheric pressure chemical ionization mass spectrometry of retro ‐carotenoids
inferred← citeshttps://doi.org/10.1016/b978-0-08-102688-5.00059-3openalex-snapshot
Diiron Enzyme Structure and Catalysis
inferred← citeshttps://doi.org/10.1016/j.agrformet.2025.110427openalex-snapshot
Winter leaf reddening and photoprotection accessed by vegetation indices and its influence on canopy light-use efficiency of a Japanese cypress (Chamaecyparis obtusa) forest
inferred← citeshttps://doi.org/10.1016/j.foodchem.2020.127370openalex-snapshot
The impact of (E/Z)-isomerization and aggregation on the color of rhodoxanthin formulations for food and beverages
inferred← citeshttps://doi.org/10.1016/j.tifs.2023.04.016openalex-snapshot
Rhodoxanthin: The new hit of the natural carotenoids market?
inferred← citeshttps://doi.org/10.1016/j.tifs.2025.105410openalex-snapshot
Integrating biosynthesis insights with biotechnological potential of bioactive carotenoids in food systems
inferred← citeshttps://doi.org/10.1111/mec.70065openalex-snapshot
Bdh1l Gene Expression Is a Potential Molecular Factor in the Evolution of Carotenoid‐Based Colour Diversity of Cichlid Fishes
inferred← citeshttps://doi.org/10.3390/foods14060968openalex-snapshot
Stabilization of β-Carotene Liposomes with Chitosan–Lactoferrin Coating System: Vesicle Properties and Anti-Inflammatory In Vitro Studies
inferred← citeshttps://doi.org/10.3390/nu14193898openalex-snapshot
Haskap Berry Leaves (Lonicera caerulea L.)—The Favorable Potential of Medical Use
inferred← citeshttps://doi.org/10.48130/forres-0025-0015openalex-snapshot
Photoprotective pigment plasticity and cold acclimation strategies in Cryptomeria japonica across two common gardens
inferred← citeshttps://doi.org/10.70675/364aaddaza093z47cdzb4d8ze451dc5612f5openalex-snapshot
Exploring linker's sequence diversity in protein fusion for the biosynthesis of zeaxanthin.
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