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Injectable hydrogel with MSNs/microRNA-21-5p delivery enables both immunomodification and enhanced angiogenesis for myocardial infarction therapy in pigs

https://doi.org/10.1126/sciadv.abd6740
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/adhm.201500778openalex-snapshot
Photocleavable Hydrogels for Light‐Triggered siRNA Release
inferredcites →https://doi.org/10.1002/adhm.201700159openalex-snapshot
Injectable Supramolecular Hydrogels as Delivery Agents of Bcl‐2 Conversion Gene for the Effective Shrinkage of Therapeutic Resistance Tumors
inferredcites →https://doi.org/10.1002/chem.201003144openalex-snapshot
Localized, Targeted, and Sustained siRNA Delivery
inferredcites →https://doi.org/10.1002/prca.201300099openalex-snapshot
The pig as an animal model for human pathologies: A proteomics perspective
inferredcites →https://doi.org/10.1007/s11914-020-00587-2openalex-snapshot
Delivery of RNAi-Based Therapeutics for Bone Regeneration
inferredcites →https://doi.org/10.1016/j.actbio.2018.06.007openalex-snapshot
RNA interfering molecule delivery from in situ forming biodegradable hydrogels for enhancement of bone formation in rat calvarial bone defects
inferredcites →https://doi.org/10.1016/j.biomaterials.2010.11.075openalex-snapshot
Delivery of basic fibroblast growth factor with a pH-responsive, injectable hydrogel to improve angiogenesis in infarcted myocardium
inferredcites →https://doi.org/10.1016/j.biomaterials.2011.08.042openalex-snapshot
The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis
inferredcites →https://doi.org/10.1016/j.biomaterials.2013.03.052openalex-snapshot
The promotion of bone regeneration through positive regulation of angiogenic–osteogenic coupling using microRNA-26a
inferredcites →https://doi.org/10.1016/j.canlet.2017.03.032openalex-snapshot
MiRNA-29b suppresses tumor growth through simultaneously inhibiting angiogenesis and tumorigenesis by targeting Akt3
inferredcites →https://doi.org/10.1016/j.devcel.2016.01.018openalex-snapshot
Mechanisms of Cardiac Regeneration
inferredcites →https://doi.org/10.1016/j.ejpb.2018.02.023openalex-snapshot
Development of controlled drug delivery systems for bone fracture-targeted therapeutic delivery: A review
inferredcites →https://doi.org/10.1016/j.jconrel.2015.09.066openalex-snapshot
Technologies for controlled, local delivery of siRNA
inferredcites →https://doi.org/10.1016/j.mvr.2007.08.005openalex-snapshot
Therapeutic myocardial angiogenesis
inferredcites →https://doi.org/10.1016/j.surg.2004.04.015openalex-snapshot
Determinants of regional myocardial acidosis during cardiac surgery
inferredcites →https://doi.org/10.1021/acs.nanolett.6b02536openalex-snapshot
Ultrasensitive pH Triggered Charge/Size Dual-Rebound Gene Delivery System
inferredcites →https://doi.org/10.1021/acsnano.7b03088openalex-snapshot
Stimuli-Responsive “Cluster Bomb” for Programmed Tumor Therapy
inferredcites →https://doi.org/10.1038/428138aopenalex-snapshot
Creation of long-lasting blood vessels
inferredcites →https://doi.org/10.1038/gt.2011.50openalex-snapshot
MicroRNA therapeutics
inferredcites →https://doi.org/10.1038/mt.2015.101openalex-snapshot
MiR-26a Rescues Bone Regeneration Deficiency of Mesenchymal Stem Cells Derived From Osteoporotic Mice
inferredcites →https://doi.org/10.1038/nature01320openalex-snapshot
Points of control in inflammation
inferredcites →https://doi.org/10.1038/nature02446openalex-snapshot
Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts
inferredcites →https://doi.org/10.1038/nature11739openalex-snapshot
Functional screening identifies miRNAs inducing cardiac regeneration
inferredcites →https://doi.org/10.1038/ncomms10376openalex-snapshot
Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects
inferredcites →https://doi.org/10.1038/nmat3922openalex-snapshot
Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition
inferredcites →https://doi.org/10.1038/nri2448openalex-snapshot
Exploring the full spectrum of macrophage activation
inferredcites →https://doi.org/10.1038/s41551-017-0157-yopenalex-snapshot
Sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischaemic injury
inferredcites →https://doi.org/10.1038/s41551-018-0229-7openalex-snapshot
Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells
inferredcites →https://doi.org/10.1038/s41586-019-1191-6openalex-snapshot
MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs
inferredcites →https://doi.org/10.1073/pnas.1015623108openalex-snapshot
Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair
inferredcites →https://doi.org/10.1073/pnas.1303377110openalex-snapshot
Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles
inferredcites →https://doi.org/10.1073/pnas.181177898openalex-snapshot
Mobilized bone marrow cells repair the infarcted heart, improving function and survival
inferredcites →https://doi.org/10.1073/pnas.94.4.1074openalex-snapshot
Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300
inferredcites →https://doi.org/10.1089/ars.2012.4849openalex-snapshot
Angiogenesis in the Infarcted Myocardium
inferredcites →https://doi.org/10.1089/wound.2011.0327openalex-snapshot
siRNA Delivery from an Injectable Scaffold for Wound Therapy
inferredcites →https://doi.org/10.1093/eurheartj/ehq253openalex-snapshot
Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde
inferredcites →https://doi.org/10.1111/ajt.13878openalex-snapshot
Micro and Nano Material Carriers for Immunomodulation
inferredcites →https://doi.org/10.1126/sciadv.1400183openalex-snapshot
Role of Toll-like receptors in diabetic renal lesions in a miniature pig model
inferredcites →https://doi.org/10.1126/sciadv.aaw0254openalex-snapshot
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype
inferredcites →https://doi.org/10.1126/science.1242551openalex-snapshot
Gene Therapy That Works
inferredcites →https://doi.org/10.1126/scitranslmed.3003841openalex-snapshot
Instructive Nanofiber Scaffolds with VEGF Create a Microenvironment for Arteriogenesis and Cardiac Repair
inferredcites →https://doi.org/10.1128/mcb.10.7.3709openalex-snapshot
The c-myc proto-oncogene regulates cardiac development in transgenic mice.
inferredcites →https://doi.org/10.1128/mcb.10.7.3709-3716.1990openalex-snapshot
The c-myc Proto-Oncogene Regulates Cardiac Development in Transgenic Mice
inferredcites →https://doi.org/10.1152/ajpgi.00507.2005openalex-snapshot
Administration of r-VEGF-A prevents hepatic artery ligation-induced bile duct damage in bile duct ligated rats
inferredcites →https://doi.org/10.1155/2013/491497openalex-snapshot
Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair
inferredcites →https://doi.org/10.1161/circresaha.116.310058openalex-snapshot
Cardiomyocyte Proliferation
inferredcites →https://doi.org/10.1172/jci25878openalex-snapshot
Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers
inferredcites →https://doi.org/10.1172/jci89786openalex-snapshot
Redirecting cardiac growth mechanisms for therapeutic regeneration
inferredcites →https://doi.org/10.1182/blood-2006-01-012369openalex-snapshot
MicroRNAs modulate the angiogenic properties of HUVECs
inferredcites →https://doi.org/10.1242/dev.132910openalex-snapshot
Building and re-building the heart by cardiomyocyte proliferation
inferredcites →https://doi.org/10.1242/jcs.066399openalex-snapshot
Breaking down the barriers: siRNA delivery and endosome escape
inferredcites →https://doi.org/10.2147/ijn.s150918openalex-snapshot
Lipopolysaccharide-induced inflammation in monocytes/macrophages is blocked by liposomal delivery of Gi-protein inhibitor
inferredcites →https://doi.org/10.2147/ijn.s57934openalex-snapshot
Immunotoxicity of silicon dioxide nanoparticles with different sizes and electrostatic charge
inferredcites →https://doi.org/10.2217/nnm-2016-0088openalex-snapshot
Light-Triggered RNA Release and Induction of Hmsc Osteogenesis Via Photodegradable, Dual-Crosslinked Hydrogels
inferredcites →https://doi.org/10.2217/nnm-2017-0061openalex-snapshot
Inorganic Nanoparticles As Potential Regulators of Immune Response in Dendritic Cells
inferredcites →https://doi.org/10.2217/nnm-2018-0076openalex-snapshot
The Toxicity of Silica Nanoparticles to the Immune System
inferredcites →https://doi.org/10.3389/fcvm.2017.00074openalex-snapshot
Platelet-Derived Microvesicles in Cardiovascular Diseases
inferredcites →https://doi.org/10.3389/fcvm.2019.00117openalex-snapshot
Large Animal Models of Heart Failure With Reduced Ejection Fraction (HFrEF)
inferredcites →https://doi.org/10.3390/pharmaceutics11040149openalex-snapshot
Feasibility Study of Mesoporous Silica Particles for Pulmonary Drug Delivery: Therapeutic Treatment with Dexamethasone in a Mouse Model of Airway Inflammation
inferredcites →https://doi.org/10.5152/akd.2014.5731openalex-snapshot
Mortality in heart failure patients

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/advs.202304627openalex-snapshot
3D Chiral Self‐Assembling Matrixes for Regulating Polarization of Macrophages and Enhance Repair of Myocardial Infarction
inferred← citeshttps://doi.org/10.1002/advs.202305895openalex-snapshot
Nanosponge for Iron Chelation and Efflux: A Ferroptosis‐Inhibiting Approach for Myocardial Infarction Therapy
inferred← citeshttps://doi.org/10.1002/advs.202306884openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/advs.202402267openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/advs.202410590openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/advs.202412360openalex-snapshot
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piR112710 attenuates diabetic cardiomyopathy through inhibiting Txnip/NLRP3-mediated pyroptosis in db/db mice
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A novel approach in biomedical engineering: The use of polyvinyl alcohol hydrogel encapsulating human umbilical cord mesenchymal stem cell-derived exosomes for enhanced osteogenic differentiation and angiogenesis in bone regeneration
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.144862openalex-snapshot
A review of stimuli-responsive hydrogels for RNA delivery: From material innovations to clinical barriers
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.147197openalex-snapshot
Anti-inflammatory and osteogenic nanofibrous scaffolds of bioactive glass/carboxymethyl chitosan-reinforced PCL short fibers for alveolar bone regeneration
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.126153openalex-snapshot
Nanodrug targeting for myocardial ischemia-reperfusion injury: mechanisms, therapeutic strategies, and challenges in clinical translation
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2026.126643openalex-snapshot
Nanotechnology-driven heart targeting to fulfil the potential of cardiac microRNA therapies
inferred← citeshttps://doi.org/10.1016/j.isci.2023.107662openalex-snapshot
Application of locally responsive design of biomaterials based on microenvironmental changes in myocardial infarction
inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.08.006openalex-snapshot
Immunomodulation of MiRNA-223-based nanoplatform for targeted therapy in retinopathy of prematurity
inferred← citeshttps://doi.org/10.1016/j.jconrel.2023.09.032openalex-snapshot
Protein-based delivery systems for RNA delivery
inferred← citeshttps://doi.org/10.1016/j.jconrel.2025.114484openalex-snapshot
Engineered mesenchymal stem cells for targeted delivery of H2S to suppress cGAS-STING inflammation and enhance cardioprotection in myocardial ischemia-reperfusion
inferred← citeshttps://doi.org/10.1016/j.jconrel.2026.115170openalex-snapshot
Advances in RNA delivery to extrahepatic tissues and cells
inferred← citeshttps://doi.org/10.1016/j.jddst.2025.106782openalex-snapshot
Therapeutic drug delivery system for ischemic heart disease based on hydrogel carriers
inferred← citeshttps://doi.org/10.1016/j.jmst.2024.07.028openalex-snapshot
An injectable hydrogel containing versatile nanoparticles with antioxidant and antifibrotic properties for myocardial infarction treatment
inferred← citeshttps://doi.org/10.1016/j.jshs.2026.101175openalex-snapshot
Exercise mitigates cardiac dysfunction post MI in ovariectomized mice via miR-21/Sox7-mediated suppression of cardiac fibroblast activation
inferred← citeshttps://doi.org/10.1016/j.jtcvs.2023.07.014openalex-snapshot
Stem cell-derived exosome patch with coronary artery bypass graft restores cardiac function in chronically ischemic porcine myocardium
inferred← citeshttps://doi.org/10.1016/j.lfs.2025.123424openalex-snapshot
MicroRNAs in vascular smooth muscle cells: Mechanisms, therapeutic potential, and advances in delivery systems
inferred← citeshttps://doi.org/10.1016/j.matdes.2022.110986openalex-snapshot
A pain reflex-inspired hydrogel for refractory wound healing
inferred← citeshttps://doi.org/10.1016/j.matdes.2025.114635openalex-snapshot
Beyond static scaffolds: glucose-responsive hydrogels as dynamic intelligent platform for tissue engineering
inferred← citeshttps://doi.org/10.1016/j.mattod.2026.103351openalex-snapshot
From edits to Circuits: Nucleic acid therapeutics for Correcting human disease
inferred← citeshttps://doi.org/10.1016/j.molmed.2024.03.004openalex-snapshot
SnoRNAs in cardiovascular development, function, and disease
inferred← citeshttps://doi.org/10.1016/j.mtadv.2026.100729openalex-snapshot
Application of injectable hydrogels in immunotherapy via the cGAS-STING pathway for cancer and inflammatory disease treatment
inferred← citeshttps://doi.org/10.1016/j.mtbio.2024.100978openalex-snapshot
Hydrogel-based cardiac repair and regeneration function in the treatment of myocardial infarction
inferred← citeshttps://doi.org/10.1016/j.mtbio.2025.101476openalex-snapshot
Innovative approaches to boost mesenchymal stem cells efficacy in myocardial infarction therapy
inferred← citeshttps://doi.org/10.1016/j.mtbio.2025.102147openalex-snapshot
Research progress on the advantages, mechanisms and design strategies of nanomaterials for immunomodulatory angiogenesis
inferred← citeshttps://doi.org/10.1016/j.mtbio.2026.102976openalex-snapshot
Hepatic cavernous hemangioma decellularized extracellular matrix/GelMA composite hydrogel promotes angiogenesis via the ITGA9–FAK–ERK1/2 axis
inferred← citeshttps://doi.org/10.1016/j.mtbio.2026.103048openalex-snapshot
Intelligent design and application of molecular recognition hydrogels in tissue engineering
inferred← citeshttps://doi.org/10.1016/j.mtcomm.2025.113232openalex-snapshot
Bioinspired injectable hydrogels for microenvironment modulation in myocardial infarction: Recent advances and outlook
inferred← citeshttps://doi.org/10.1016/j.nano.2022.102618openalex-snapshot
Delivery of Mir-196c-3p with NIR-II light-triggered gel attenuates cardiomyocyte ferroptosis in cardiac ischemia-reperfusion injury
inferred← citeshttps://doi.org/10.1016/j.nantod.2021.101227openalex-snapshot
Artificial apoptotic cells/VEGF-loaded injectable hydrogel united with immunomodification and revascularization functions to reduce cardiac remodeling after myocardial infarction
inferred← citeshttps://doi.org/10.1016/j.phymed.2026.158619openalex-snapshot
Targeting TOM70 crotonylation to improve hypoxic vascular dysfunction: A new strategy for treating myocardial infarction
inferred← citeshttps://doi.org/10.1016/j.polymertesting.2023.108109openalex-snapshot
Injectable EC-BMSC hydrogel with prolonged VEGF action for enhanced angiogenesis
inferred← citeshttps://doi.org/10.1016/j.rineng.2026.110396openalex-snapshot
Emerging roles of mesoporous silica nanoparticles in personalized medicine: revolutionizing therapy and diagnosis — a comprehensive review
inferred← citeshttps://doi.org/10.1016/j.semcdb.2021.07.007openalex-snapshot
Non-coding RNAs in cardiac regeneration: Mechanism of action and therapeutic potential
inferred← citeshttps://doi.org/10.1016/j.stem.2022.04.002openalex-snapshot
Biomaterials to enhance stem cell transplantation
inferred← citeshttps://doi.org/10.1016/j.vesic.2022.100010openalex-snapshot
Greasing wheels of cell-free therapies for cardiovascular diseases: Integrated devices of exosomes/exosome-like nanovectors with bioinspired materials
inferred← citeshttps://doi.org/10.1016/j.xcrm.2025.101987openalex-snapshot
Injectable hydrogel with miR-222-engineered extracellular vesicles ameliorates myocardial ischemic reperfusion injury via mechanotransduction
inferred← citeshttps://doi.org/10.1021/acs.chemrev.2c00179openalex-snapshot
Self-Healing Injectable Hydrogels for Tissue Regeneration
inferred← citeshttps://doi.org/10.1021/acs.chemrev.3c00611openalex-snapshot
Chemically Modified Platforms for Better RNA Therapeutics
inferred← citeshttps://doi.org/10.1021/acs.chemrev.4c00923openalex-snapshot
Hitchhiking Delivery Systems: Therapeutic Hydrogels as Advanced Tools for Immunomodulatory Applications
inferred← citeshttps://doi.org/10.1021/acs.langmuir.3c01269openalex-snapshot
Peptide Hydrogels and Nanostructures Controlling Biological Machinery
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.2c00650openalex-snapshot
Insight into Heart-Tailored Architectures of Hydrogel to Restore Cardiac Functions after Myocardial Infarction
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.4c00595openalex-snapshot
Hydrogels as a Potential Biomaterial for Multimodal Therapeutic Applications
inferred← citeshttps://doi.org/10.1021/acsami.2c11574openalex-snapshot
Decorated Polyetheretherketone Implants with Antibacterial and Antioxidative Effects through Layer-by-Layer Nanoarchitectonics Facilitate Diabetic Bone Integration with Infection
inferred← citeshttps://doi.org/10.1021/acsami.3c10053openalex-snapshot
Silicon–Carbon Dots-Loaded Mesoporous Silica Nanocomposites (mSiO2@SiCDs): An Efficient Dual Inhibitor of Cu2+-Mediated Oxidative Stress and Aβ Aggregation for Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1021/acsami.4c03598openalex-snapshot
From Bone Remodeling to Wound Healing: An miR-146a-5p-Loaded Nanocarrier Targets Endothelial Cells to Promote Angiogenesis
inferred← citeshttps://doi.org/10.1021/acsbiomaterials.2c01252openalex-snapshot
Electrostatic Assembly of Multiarm PEG-Based Hydrogels as Extracellular Matrix Mimics: Cell Response in the Presence and Absence of RGD Cell Adhesive Ligands
inferred← citeshttps://doi.org/10.1021/acsmaterialslett.4c02108openalex-snapshot
Combating Cellular Aging: Frontiers in Biomaterials and Therapies
inferred← citeshttps://doi.org/10.1021/acsnano.2c00734openalex-snapshot
Aggregation-Induced Emission Nanoparticles for Single Near-Infrared Light-Triggered Photodynamic and Photothermal Antibacterial Therapy
inferred← citeshttps://doi.org/10.1021/acsnano.2c05168openalex-snapshot
An Intrapericardial Injectable Hydrogel Patch for Mechanical–Electrical Coupling with Infarcted Myocardium
inferred← citeshttps://doi.org/10.1021/acsnano.3c08219openalex-snapshot
Bioinspired Spatiotemporal Management toward RNA Therapies
inferred← citeshttps://doi.org/10.1021/acsnano.3c08811openalex-snapshot
Nanoparticle–Patch System for Localized, Effective, and Sustained miRNA Administration into Infarcted Myocardium to Alleviate Myocardial Ischemia–Reperfusion Injury
inferred← citeshttps://doi.org/10.1021/acsnano.3c11661openalex-snapshot
One Endothelium-Targeted Combined Nucleic Acid Delivery System for Myocardial Infarction Therapy
inferred← citeshttps://doi.org/10.1021/acsnano.4c13028openalex-snapshot
Biomimetic Extracellular Vesicles Based on Composite Bioactive Ions for the Treatment of Ischemic Bone Disease
inferred← citeshttps://doi.org/10.1021/acsnano.4c14869openalex-snapshot
Ultrasmall PtIr Bimetallic Nanozyme Treats Myocardial Infarction via Ischemic/Inflammatory Cardiac Microenvironment Remodeling
inferred← citeshttps://doi.org/10.1021/acsomega.4c02037openalex-snapshot
Engineering Three-Dimensional Spheroid Culture for Enrichment of Proangiogenic miRNAs in Umbilical Cord Mesenchymal Stem Cells and Promotion of Angiogenesis
inferred← citeshttps://doi.org/10.1021/acsomega.4c04682openalex-snapshot
Application of Pro-angiogenic Biomaterials in Myocardial Infarction
inferred← citeshttps://doi.org/10.1021/acsomega.5c07004openalex-snapshot
Cross-Linking PEG Microgels with Mesoporous Organosilica Nanoparticles to Engineer Microporous Annealed Particle Scaffold Properties
inferred← citeshttps://doi.org/10.1038/s41392-022-01082-zopenalex-snapshot
Nanoparticles in the diagnosis and treatment of vascular aging and related diseases
inferred← citeshttps://doi.org/10.1038/s41392-024-01840-1openalex-snapshot
Macrophages in cardiovascular diseases: molecular mechanisms and therapeutic targets
inferred← citeshttps://doi.org/10.1038/s41427-021-00330-yopenalex-snapshot
Functional hydrogels for the treatment of myocardial infarction
inferred← citeshttps://doi.org/10.1038/s41467-024-49901-xopenalex-snapshot
Single dose of intravenous miR199a-5p delivery targeting ischemic heart for long-term repair of myocardial infarction
inferred← citeshttps://doi.org/10.1038/s41467-024-53579-6openalex-snapshot
A wearable and stretchable dual-wavelength LED device for home care of chronic infected wounds
inferred← citeshttps://doi.org/10.1038/s41467-025-64283-4openalex-snapshot
CCL28 contributes to angiogenesis and cardiac repair through CCR10+ endothelial cells after myocardial infarction in male mice
inferred← citeshttps://doi.org/10.1038/s41551-025-01420-wopenalex-snapshot
Strategies for the vascular patterning of engineered tissues for organ repair
inferred← citeshttps://doi.org/10.1038/s41563-023-01472-wopenalex-snapshot
Hydrogels for RNA delivery
inferred← citeshttps://doi.org/10.1038/s41569-025-01229-9openalex-snapshot
Non-coding RNAs in lipid metabolism and their roles in atherosclerosis
inferred← citeshttps://doi.org/10.1038/s41598-023-47079-8openalex-snapshot
Development of a potency assay for CD34+ cell-based therapy
inferred← citeshttps://doi.org/10.1038/s42003-024-06483-0openalex-snapshot
PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3
inferred← citeshttps://doi.org/10.1038/s44222-024-00213-1openalex-snapshot
Design and translation of injectable biomaterials
inferred← citeshttps://doi.org/10.1039/9781837675739-00024openalex-snapshot
The Design and Manipulation Principles of Immunomodulatory Biomaterials
inferred← citeshttps://doi.org/10.1039/bk9781837673070-00404openalex-snapshot
Injectable Smart Hydrogels for Myocardial Infarction Therapy
inferred← citeshttps://doi.org/10.1039/d1cs00707fopenalex-snapshot
How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells?
inferred← citeshttps://doi.org/10.1039/d1tb00330eopenalex-snapshot
Engineered bioresponsive nanotherapeutics: recent advances in the treatment of atherosclerosis and ischemic-related disease
inferred← citeshttps://doi.org/10.1039/d2tb01591aopenalex-snapshot
Advanced bioactive hydrogels for the treatment of myocardial infarction
inferred← citeshttps://doi.org/10.1039/d3bm01352aopenalex-snapshot
Injectable smart stimuli-responsive hydrogels: pioneering advancements in biomedical applications
inferred← citeshttps://doi.org/10.1039/d4tb02550dopenalex-snapshot
Multifunctional theranostic glyconanoprobes for synergistic eradication of breast cancer
inferred← citeshttps://doi.org/10.1039/d5mh01554eopenalex-snapshot
A “drug-carrier homologation” cardiac patch for myocardial infarction therapy via month-long controlled H 2 S release
inferred← citeshttps://doi.org/10.1039/d5tb00611bopenalex-snapshot
Injectable thermosensitive hydrogel-encapsulated paclitaxel liposomes enriched with miR-455-3p antagomir for dormancy therapy of salivary adenoid cystic carcinoma
inferred← citeshttps://doi.org/10.1063/5.0093399openalex-snapshot
Myocardial infarction from a tissue engineering and regenerative medicine point of view: A comprehensive review on models and treatments
inferred← citeshttps://doi.org/10.1063/5.0103703openalex-snapshot
Factor significance based mortality grading of heart failure patients
inferred← citeshttps://doi.org/10.1063/5.0312953openalex-snapshot
Research advances in intelligent microenvironment-responsive hydrogels for myocardial infarction therapy
inferred← citeshttps://doi.org/10.1080/14686996.2025.2485668openalex-snapshot
Rapid isolation of extracellular vesicles from stem cell conditioned medium using osmosis-driven filtration
inferred← citeshttps://doi.org/10.1080/17425247.2025.2539960openalex-snapshot
Strategies for the delivery of RNA therapeutics to diseased heart tissue
inferred← citeshttps://doi.org/10.1080/21655979.2022.2065743openalex-snapshot
Suppression of lncRNA Gm47283 attenuates myocardial infarction via miR-706/ Ptgs2/ferroptosis axis
inferred← citeshttps://doi.org/10.1089/hum.2024.113openalex-snapshot
Advances in MicroRNA Therapeutics: From Preclinical to Clinical Studies
inferred← citeshttps://doi.org/10.1093/lifemedi/lnad027openalex-snapshot
Engineered biomaterials in stem cell-based regenerative medicine
inferred← citeshttps://doi.org/10.1093/rb/rbac009openalex-snapshot
Rational design of hydrogels for immunomodulation
inferred← citeshttps://doi.org/10.1093/rb/rbac098openalex-snapshot
Recent advances in regenerative biomaterials
inferred← citeshttps://doi.org/10.1093/rb/rbae131openalex-snapshot
An immunoregulatory and metabolism-improving injectable hydrogel for cardiac repair after myocardial infarction
inferred← citeshttps://doi.org/10.1096/fj.202400737rropenalex-snapshot
Cardiomyocyte‐derived exosomes promote cardiomyocyte proliferation and neonatal heart regeneration
inferred← citeshttps://doi.org/10.1097/fjc.0000000000001305openalex-snapshot
Revisiting miRNA-21 as a Therapeutic Strategy for Myocardial Infarction: A Systematic Review
inferred← citeshttps://doi.org/10.1111/wrr.70028openalex-snapshot
Rapid angiogenic hydrogel nanofiber scaffold promotes random flap regeneration and modulates inflammation
inferred← citeshttps://doi.org/10.1124/molpharm.124.000899openalex-snapshot
New Perspectives and Prospects of microRNA Delivery in Diabetic Wound Healing
inferred← citeshttps://doi.org/10.1126/sciadv.ado1223openalex-snapshot
Nanosilicates promote angiogenesis through activation of ROS-mediated WNT/β-catenin pathway
inferred← citeshttps://doi.org/10.1155/2023/2561509openalex-snapshot
MicroRNAs Regulate Function in Atherosclerosis and Clinical Implications
inferred← citeshttps://doi.org/10.1161/atvbaha.122.318235openalex-snapshot
Hydrogels to Recapture Extracellular Matrix Cues That Regulate Vascularization
inferred← citeshttps://doi.org/10.1177/20417314241265897openalex-snapshot
Mechanisms of hydrogel-based microRNA delivery systems and its application strategies in targeting inflammatory diseases
inferred← citeshttps://doi.org/10.1177/20417314241310541openalex-snapshot
Bioengineering strategies targeting angiogenesis: Innovative solutions for osteonecrosis of the femoral head
inferred← citeshttps://doi.org/10.1186/s10020-021-00352-wopenalex-snapshot
Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis
inferred← citeshttps://doi.org/10.1186/s11658-023-00491-4openalex-snapshot
Macrophage-driven cardiac inflammation and healing: insights from homeostasis and myocardial infarction
inferred← citeshttps://doi.org/10.1186/s12872-024-03742-0openalex-snapshot
Injectable hydrogel-based combination therapy for myocardial infarction: a systematic review and Meta-analysis of preclinical trials
inferred← citeshttps://doi.org/10.1186/s12951-021-01157-zopenalex-snapshot
Acupoint nanocomposite hydrogel for simulation of acupuncture and targeted delivery of triptolide against rheumatoid arthritis
inferred← citeshttps://doi.org/10.1186/s12951-022-01315-xopenalex-snapshot
Nanoarchitectured prototypes of mesoporous silica nanoparticles for innovative biomedical applications
inferred← citeshttps://doi.org/10.1186/s12951-023-02063-2openalex-snapshot
Application of biomedical materials in the diagnosis and treatment of myocardial infarction
inferred← citeshttps://doi.org/10.1186/s12951-024-02462-zopenalex-snapshot
Developing hydrogels for gene therapy and tissue engineering
inferred← citeshttps://doi.org/10.1186/s12951-024-02685-0openalex-snapshot
Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair
inferred← citeshttps://doi.org/10.1186/s13018-025-06503-7openalex-snapshot
Localized therapeutic strategy based on microRNA-21-loaded mesoporous silica nanoparticles hydrogel improves bone repair in medication-related osteonecrosis of the jaw
inferred← citeshttps://doi.org/10.1186/s13287-025-04277-7openalex-snapshot
3D culturing as a promising strategy to enhance the angiogenic potential of adipose stem cell-derived secretome: insights into the role of miR-145-5p/ANGPT2 axis
inferred← citeshttps://doi.org/10.1186/s13578-023-00960-5openalex-snapshot
Loss of TET2 impairs endothelial angiogenesis via downregulating STAT3 target genes
inferred← citeshttps://doi.org/10.1186/s40779-025-00664-6openalex-snapshot
Engineered immune-driven theranostics for clinical cardiology
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