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Femtomolar Sensitivity of Metalloregulatory Proteins Controlling Zinc Homeostasis

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Zinc enzymes
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The Cyanobacterial Repressor SmtB Is Predominantly a Dimer and Binds Two Zn2+ Ions per Subunit
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ZntR is a Zn(II)‐responsive MerR‐like transcriptional regulator of zntA in Escherichia coli
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ZntR is an autoregulatory protein and negatively regulates the chromosomal zinc resistance operon znt of Staphylococcus aureus
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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
inferredcites →https://doi.org/10.1073/pnas.95.18.10728openalex-snapshot
An SmtB-like repressor from Synechocystis PCC 6803 regulates a zinc exporter
inferredcites →https://doi.org/10.1074/jbc.274.14.9183openalex-snapshot
Metallothionein Is Part of a Zinc-scavenging Mechanism for Cell Survival under Conditions of Extreme Zinc Deprivation
inferredcites →https://doi.org/10.1074/jbc.274.53.37517openalex-snapshot
DNA Distortion Mechanism for Transcriptional Activation by ZntR, a Zn(II)-responsive MerR Homologue in Escherichia coli
inferredcites →https://doi.org/10.1074/jbc.c000172200openalex-snapshot
Energetics of Copper Trafficking between the Atx1 Metallochaperone and the Intracellular Copper Transporter, Ccc2
inferredcites →https://doi.org/10.1074/jbc.m001775200openalex-snapshot
The Zinc-responsive Regulator Zur and Its Control of theznu Gene Cluster Encoding the ZnuABC Zinc Uptake System in Escherichia coli
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Isolation of a prokaryotic metallothionein locus and analysis of transcriptional control by trace metal ions
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Identification of a Zinc-Specific Metalloregulatory Protein, Zur, Controlling Zinc Transport Operons in Bacillus subtilis
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Families of Soft-Metal-Ion-Transporting ATPases
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Growth Phase-Dependent Variation in Protein Composition of the Escherichia coli Nucleoid
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The importance of siderophores in iron nutrition of heterotrophic marine bacteria

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Effects of Zn(Ii) on the Performance and Microbial Community of Simultaneous Nitrification and Denitrification (Snd) in a Sequencing Batch Biofilm Reactor (Sbbr)
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MetalloregulationBased in part on the article Metalloregulation by Robert P. Hausinger which appeared in theEncyclopedia of Inorganic Chemistry, First Edition.
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Metal Homeostasis
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Metalloregulatory Proteins
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Near‐Infrared Photothermally Activated DNAzyme–Gold Nanoshells for Imaging Metal Ions in Living Cells
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Imaging Endogenous Metal Ions in Living Cells Using a DNAzyme–Catalytic Hairpin Assembly Probe
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EPR Spectroscopy Detects Various Active State Conformations of the Transcriptional Regulator CueR
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DNAzyme‐Loaded Metal–Organic Frameworks (MOFs) for Self‐Sufficient Gene Therapy
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DNAzyme‐Mediated Genetically Encoded Sensors for Ratiometric Imaging of Metal Ions in Living Cells
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inferred← citeshttps://doi.org/10.1007/978-1-59745-462-9_13openalex-snapshot
MRI of Brain Iron and Neurodegenerative Diseases: A Potential Biomarker
inferred← citeshttps://doi.org/10.1007/978-1-59745-462-9_4openalex-snapshot
Iron as Nutrient: Strategies for Iron Acquisition and Usage by Pathogenic Microorganisms
inferred← citeshttps://doi.org/10.1007/978-3-030-76235-3_10openalex-snapshot
Metallothioneins’ Responses on Impact of Metal-Based Nanomaterials for Biomedical Use
inferred← citeshttps://doi.org/10.1007/978-3-030-76609-2_9openalex-snapshot
Role of Zinc Homeostasis in Plant Growth
inferred← citeshttps://doi.org/10.1007/978-3-030-97185-4_14openalex-snapshot
Microbial Metabolism of Nickel
inferred← citeshttps://doi.org/10.1007/978-3-031-33957-8_15openalex-snapshot
Organic Approaches Toward Iron and Zinc Biofortification in Legume Crops
inferred← citeshttps://doi.org/10.1007/978-3-031-61877-2_10openalex-snapshot
Metallothionein-Antworten auf den Einfluss von metallbasierten Nanomaterialien für den biomedizinischen Gebrauch
inferred← citeshttps://doi.org/10.1007/978-3-319-20164-1_6openalex-snapshot
Recombinant Intrinsically Disordered Proteins for NMR: Tips and Tricks
inferred← citeshttps://doi.org/10.1007/978-3-319-89833-9_6openalex-snapshot
Dark Septate Endophytes and Mycorrhizal Fungi of Trees Affected by Metal Pollution
inferred← citeshttps://doi.org/10.1007/978-3-319-90143-5_3openalex-snapshot
Environmental Metallomics
inferred← citeshttps://doi.org/10.1007/978-3-540-87978-7_8openalex-snapshot
Mechanisms Underlying Heavy Metal Tolerance in Arbuscular Mycorrhizas
inferred← citeshttps://doi.org/10.1007/978-3-642-10613-2_12openalex-snapshot
Zn – A Versatile Player in Plant Cell Biology
inferred← citeshttps://doi.org/10.1007/978-3-642-13431-9_14openalex-snapshot
Metal Transport
inferred← citeshttps://doi.org/10.1007/978-3-642-14369-4_4openalex-snapshot
Iron Transport and Signaling in Plants
inferred← citeshttps://doi.org/10.1007/978-3-642-21408-0_7openalex-snapshot
The Role of Membrane Transport in the Detoxification and Accumulation of Zinc in Plants
inferred← citeshttps://doi.org/10.1007/978-4-431-55114-0_15openalex-snapshot
Zinc as a Key Meiotic Cell-Cycle Regulator in the Mammalian Oocyte
inferred← citeshttps://doi.org/10.1007/978-4-431-55114-0_4openalex-snapshot
Oxidative Stress and Neuronal Zinc Signaling
inferred← citeshttps://doi.org/10.1007/978-4-431-56463-8_11openalex-snapshot
Comprehensive Element Analysis of Prokaryotic and Eukaryotic Cells as well as Organelles by ICP-MS
inferred← citeshttps://doi.org/10.1007/978-90-481-9852-8_12openalex-snapshot
State-of-the-Art Chemical Analyses: Xenobiotics, Plant Proteomics, and Residues in Plant Based Products
inferred← citeshttps://doi.org/10.1007/978-94-007-1599-8_12openalex-snapshot
Dark Septate Endophytes and Mycorrhizal Fungi of Trees Affected by Pollution
inferred← citeshttps://doi.org/10.1007/978-94-007-2172-2_1openalex-snapshot
Characterization of Metal Ion-Nucleic Acid Interactions in Solution
inferred← citeshttps://doi.org/10.1007/978-94-007-5561-1_11openalex-snapshot
Nickel Metallomics: General Themes Guiding Nickel Homeostasis
inferred← citeshttps://doi.org/10.1007/978-981-10-1950-0_7openalex-snapshot
Selective Metal Ion Homeostasis in Cyanobacteria
inferred← citeshttps://doi.org/10.1007/978-981-10-5514-0_13openalex-snapshot
Plant-Microbe-Metal Interactions: Basics, Recent Advances, and Future Trends
inferred← citeshttps://doi.org/10.1007/978-981-15-0557-7_19openalex-snapshot
Zinc Signals in Biology
inferred← citeshttps://doi.org/10.1007/978-981-15-1902-4_17openalex-snapshot
Microbiological Advances in Bioactives from High Altitude
inferred← citeshttps://doi.org/10.1007/s00018-004-4214-9openalex-snapshot
Metallo-?-lactamases: two binding sites for one catalytic metal ion?
inferred← citeshttps://doi.org/10.1007/s00018-026-06137-wopenalex-snapshot
ZIP-ZnT1 complexes mediate a local Zn2+-cycle regulating neuronal Zn²⁺ transport
inferred← citeshttps://doi.org/10.1007/s00203-004-0670-8openalex-snapshot
Identification of a regulatory pathway that controls the heavy-metal resistance system Czc via promoter czcNp in Ralstonia metallidurans
inferred← citeshttps://doi.org/10.1007/s00203-006-0126-4openalex-snapshot
Iron nutrition and physiological responses to iron stress in Nitrosomonas europaea
inferred← citeshttps://doi.org/10.1007/s00203-007-0341-7openalex-snapshot
Genome-wide transcriptional responses of Nitrosomonas europaea to zinc
inferred← citeshttps://doi.org/10.1007/s00216-003-2333-zopenalex-snapshot
Metallomics: a new frontier in analytical chemistry
inferred← citeshttps://doi.org/10.1007/s00216-007-1635-yopenalex-snapshot
Variation in the isotopic composition of zinc in the natural environment and the use of zinc isotopes in biogeosciences: a review
inferred← citeshttps://doi.org/10.1007/s00216-007-1690-4openalex-snapshot
Metal-binding molecules in the organs of Mus musculus by size-exclusion chromatography coupled with UV spectroscopy and ICP-MS
inferred← citeshttps://doi.org/10.1007/s00249-021-01539-zopenalex-snapshot
A study on the secondary structure of the metalloregulatory protein CueR: effect of pH, metal ions and DNA
inferred← citeshttps://doi.org/10.1007/s00253-015-6922-5openalex-snapshot
The ZntA-like NpunR4017 plays a key role in maintaining homeostatic levels of zinc in Nostoc punctiforme
inferred← citeshttps://doi.org/10.1007/s00253-020-10346-zopenalex-snapshot
Identification of Zur boxes and determination of their roles in the differential regulation of the Zur regulon in Agrobacterium tumefaciens C58
inferred← citeshttps://doi.org/10.1007/s00289-017-2119-7openalex-snapshot
Colorimetric chemosensor for Zn2+ based on pyrogallol red and poly(diallyldimethylammonium chloride) in aqueous solution
inferred← citeshttps://doi.org/10.1007/s00424-003-1074-3openalex-snapshot
The SLC39 family of metal ion transporters
inferred← citeshttps://doi.org/10.1007/s00424-010-0809-1openalex-snapshot
Glutamate receptors, neurotoxicity and neurodegeneration
inferred← citeshttps://doi.org/10.1007/s00425-003-1091-7openalex-snapshot
Localization and functional characterization of metal-binding sites in phytochelatin synthases
inferred← citeshttps://doi.org/10.1007/s00449-011-0562-7openalex-snapshot
A study on the dynamics of the zraP gene expression profile and its application to the construction of zinc adsorption bacteria
inferred← citeshttps://doi.org/10.1007/s00775-004-0535-2openalex-snapshot
The binding of iron and zinc to glyoxalase II occurs exclusively as di-metal centers and is unique within the metallo-β-lactamase family
inferred← citeshttps://doi.org/10.1007/s00775-004-0607-3openalex-snapshot
Effect of complex formation between Zn2+ ions and the anticancer drug mithramycin upon enzymatic activity of zinc(II)-dependent alcohol dehydrogenase
inferred← citeshttps://doi.org/10.1007/s00775-005-0647-3openalex-snapshot
The time-dependent transport of chromium in adult rats from the bloodstream to the urine
inferred← citeshttps://doi.org/10.1007/s00775-006-0150-5openalex-snapshot
Zinc-buffering capacity of a eukaryotic cell at physiological pZn
inferred← citeshttps://doi.org/10.1007/s00775-010-0621-6openalex-snapshot
Characterizing metalloendonuclease mixed metal complexes by global kinetic analysis
inferred← citeshttps://doi.org/10.1007/s00775-014-1140-7openalex-snapshot
Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins
inferred← citeshttps://doi.org/10.1007/s00775-016-1421-4openalex-snapshot
Some nontoxic metal-based drugs for selected prevalent tropical pathogenic diseases
inferred← citeshttps://doi.org/10.1007/s00775-019-01667-0openalex-snapshot
Emergence of metal selectivity and promiscuity in metalloenzymes
inferred← citeshttps://doi.org/10.1007/s00775-021-01864-wopenalex-snapshot
Low-molecular-mass labile metal pools in Escherichia coli: advances using chromatography and mass spectrometry
inferred← citeshttps://doi.org/10.1007/s00775-025-02112-1openalex-snapshot
Bioinorganic chemistry: where from and where to?
inferred← citeshttps://doi.org/10.1007/s00792-007-0118-6openalex-snapshot
Insights into different dependence of dNTP triphosphohydrolase on metal ion species from intracellular ion concentrations in Thermus thermophilus
inferred← citeshttps://doi.org/10.1007/s10123-025-00735-7openalex-snapshot
Zinc-mediated changes to cytosol osmolyte and lipid profiles in soil fungi under growth-stimulating conditions
inferred← citeshttps://doi.org/10.1007/s10295-005-0224-3openalex-snapshot
New developments in the understanding of the cation diffusion facilitator family
inferred← citeshttps://doi.org/10.1007/s10495-010-0520-xopenalex-snapshot
Zinc induced apoptotic death of mouse dendritic cells
inferred← citeshttps://doi.org/10.1007/s10522-006-9046-6openalex-snapshot
Inflammation, genes and zinc in ageing and age-related diseases
inferred← citeshttps://doi.org/10.1007/s10534-005-3716-8openalex-snapshot
Structural Determinants of Metal Selectivity in Prokaryotic Metal-responsive Transcriptional Regulators
inferred← citeshttps://doi.org/10.1007/s10534-005-3717-7openalex-snapshot
A Design for Life: Prokaryotic Metal-binding MerR Family Regulators
inferred← citeshttps://doi.org/10.1007/s10534-005-4576-yopenalex-snapshot
Tracing of labile zinc in live fish hepatocytes using FluoZin-3
inferred← citeshttps://doi.org/10.1007/s10534-006-9039-6openalex-snapshot
The RcnRA (YohLM) system of Escherichia coli: A connection between nickel, cobalt and iron homeostasis
inferred← citeshttps://doi.org/10.1007/s10534-006-9055-6openalex-snapshot
The structure and function of heavy metal transport P1B-ATPases
inferred← citeshttps://doi.org/10.1007/s10534-006-9059-2openalex-snapshot
The bacterial metallome: composition and stability with specific reference to the anaerobic bacterium Desulfovibrio desulfuricans
inferred← citeshttps://doi.org/10.1007/s10534-006-9070-7openalex-snapshot
Functional specialization within the Fur family of metalloregulators
inferred← citeshttps://doi.org/10.1007/s10534-008-9186-zopenalex-snapshot
Molecular aspects of human cellular zinc homeostasis: redox control of zinc potentials and zinc signals
inferred← citeshttps://doi.org/10.1007/s10534-010-9319-zopenalex-snapshot
Point mutations change specificity and kinetics of metal uptake by ZupT from Escherichia coli
inferred← citeshttps://doi.org/10.1007/s10534-011-9425-6openalex-snapshot
Escherichia coli topoisomerase I is an iron and zinc binding protein
inferred← citeshttps://doi.org/10.1007/s10534-011-9451-4openalex-snapshot
Transition metal homeostasis: from yeast to human disease
inferred← citeshttps://doi.org/10.1007/s10534-012-9604-0openalex-snapshot
Application of Zinpyr-1 for the investigation of zinc signals in Escherichia coli
inferred← citeshttps://doi.org/10.1007/s10534-013-9613-7openalex-snapshot
Inhibitory zinc sites in enzymes
inferred← citeshttps://doi.org/10.1007/s10534-013-9646-yopenalex-snapshot
Zinc regulates the activity of kinase-phosphatase pair (BasPrkC/BasPrpC) in Bacillus anthracis
inferred← citeshttps://doi.org/10.1007/s10534-015-9883-3openalex-snapshot
Acute changes in cellular zinc alters zinc uptake rates prior to zinc transporter gene expression in Jurkat cells
inferred← citeshttps://doi.org/10.1007/s10534-019-00218-zopenalex-snapshot
Protein kinase CK2 is involved in zinc homeostasis in breast and prostate cancer cells
inferred← citeshttps://doi.org/10.1007/s10534-025-00744-zopenalex-snapshot
The E. coli escape wave in response to external Zn2+ is zinc reserve-dependent
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