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Structural Basis for Double-Stranded RNA Processing by Dicer
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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RNase III enzymes and the initiation of gene silencing
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Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
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Catalytic mechanism of Escherichia coli ribonuclease III: kinetic and inhibitor evidence for the involvement of two magnesium ions in RNA phosphodiester hydrolysis
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Germ Line Transcripts Are Processed by a Dicer-Like Protein That Is Essential for Developmentally Programmed Genome Rearrangements of Tetrahymena thermophila
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Genetic and Functional Diversification of Small RNA Pathways in Plants
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inferred← citeshttps://doi.org/10.1007/s00439-012-1246-3openalex-snapshot
Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women’s Health Initiative SHARe Study
inferred← citeshttps://doi.org/10.1007/s00439-013-1271-xopenalex-snapshot
Genetic syndromes caused by mutations in epigenetic genes
inferred← citeshttps://doi.org/10.1007/s00604-017-2163-xopenalex-snapshot
Electrochemiluminescence based determination of micro-RNA using target-guided assembly of gold nanoparticles on an electrode modified with Nafion, carbon nanotubes and polyvinylpyrrolidone
inferred← citeshttps://doi.org/10.1007/s10142-009-0111-5openalex-snapshot
Dicer-like (DCL) proteins in plants
inferred← citeshttps://doi.org/10.1007/s10142-016-0495-yopenalex-snapshot
Genomes of parasitic nematodes (Meloidogyne hapla, Meloidogyne incognita, Ascaris suum and Brugia malayi) have a reduced complement of small RNA interference pathway genes: knockdown can reduce host infectivity of M. incognita
inferred← citeshttps://doi.org/10.1007/s10142-020-00745-wopenalex-snapshot
Identification and characterization of Dicer-like genes in leaf rust pathogen (Puccinia triticina) of wheat
inferred← citeshttps://doi.org/10.1007/s10265-016-0877-1openalex-snapshot
Plant dicer-like proteins: double-stranded RNA-cleaving enzymes for small RNA biogenesis
inferred← citeshttps://doi.org/10.1007/s10571-017-0515-zopenalex-snapshot
The Stress-Responding miR-132-3p Shows Evolutionarily Conserved Pathway Interactions
inferred← citeshttps://doi.org/10.1007/s10695-015-0081-6openalex-snapshot
A key gene of the small RNA pathway in the flounder, Paralichthys olivaceus: identification and functional characterization of dicer
inferred← citeshttps://doi.org/10.1007/s10709-010-9462-zopenalex-snapshot
Identification, chromosomal mapping and conserved synteny of porcine Argonaute family of genes
inferred← citeshttps://doi.org/10.1007/s10725-020-00654-9openalex-snapshot
MicroRNA biogenesis in plant
inferred← citeshttps://doi.org/10.1007/s10741-016-9572-5openalex-snapshot
MicroRNAs, heart failure, and aging: potential interactions with skeletal muscle
inferred← citeshttps://doi.org/10.1007/s11011-020-00622-2openalex-snapshot
Insulin resistance: a connecting link between Alzheimer’s disease and metabolic disorder
inferred← citeshttps://doi.org/10.1007/s11105-014-0736-yopenalex-snapshot
Identification, Characterization and Expression Profiling of Dicer-Like, Argonaute and RNA-Dependent RNA Polymerase Gene Families in Foxtail Millet
inferred← citeshttps://doi.org/10.1007/s11426-014-5115-xopenalex-snapshot
RNA interference with DNA polymerase and synthesis
inferred← citeshttps://doi.org/10.1007/s12010-012-0046-5openalex-snapshot
Advances in RNA Interference Technology and Its Impact on Nutritional Improvement, Disease and Insect Control in Plants
inferred← citeshttps://doi.org/10.1007/s12020-015-0629-3openalex-snapshot
Gene interference strategies as a new tool for the treatment of prostate cancer
inferred← citeshttps://doi.org/10.1007/s12035-015-9201-7openalex-snapshot
Are microRNAs the Molecular Link Between Metabolic Syndrome and Alzheimer’s Disease?
inferred← citeshttps://doi.org/10.1007/s12551-021-00902-wopenalex-snapshot
DICER: structure, function, and regulation
inferred← citeshttps://doi.org/10.1007/s13205-025-04300-xopenalex-snapshot
Genome-wide identification and characterization of dicer-like genes in Andrographis paniculata (Burm. f.) Wall. ex Nees and their expression response to methyl jasmonate elicitation
inferred← citeshttps://doi.org/10.1007/s13238-015-0212-yopenalex-snapshot
Biogenesis and regulation of the let-7 miRNAs and their functional implications
inferred← citeshttps://doi.org/10.1007/s13273-025-00522-5openalex-snapshot
Carcinogenic mechanism of cooking fumes based on miRNA expression analysis: a systematic review
inferred← citeshttps://doi.org/10.1007/s13277-013-0728-9openalex-snapshot
The regulatory mechanism of CCR7 gene expression and its involvement in the metastasis and progression of gastric cancer
inferred← citeshttps://doi.org/10.1007/s13277-015-3452-9openalex-snapshot
MiR-140-3p suppressed cell growth and invasion by downregulating the expression of ATP8A1 in non-small cell lung cancer
inferred← citeshttps://doi.org/10.1007/s13277-016-5378-2openalex-snapshot
The E6-TAp63β-Dicer feedback loop involves in miR-375 downregulation and epithelial-to-mesenchymal transition in HR-HPV+ cervical cancer cells
inferred← citeshttps://doi.org/10.1007/s13353-023-00750-2openalex-snapshot
MicroRNA in lung cancer—a novel potential way for early diagnosis and therapy
inferred← citeshttps://doi.org/10.1016/b978-0-08-046884-6.00223-2openalex-snapshot
Physiological and Pathological Functions of Mammalian MicroRNAs
inferred← citeshttps://doi.org/10.1016/b978-0-12-374153-0.00007-2openalex-snapshot
The Complex Interactions of Viruses and the RNAi Machinery: A Driving Force in Viral Evolution
inferred← citeshttps://doi.org/10.1016/b978-0-12-385859-7.00001-xopenalex-snapshot
MicroRNAs in Drosophila Development
inferred← citeshttps://doi.org/10.1016/b978-0-12-391429-3.00006-xopenalex-snapshot
Trichomonas vaginalis Pathobiology
inferred← citeshttps://doi.org/10.1016/b978-0-12-394447-4.10055-0openalex-snapshot
miRNAs/Small Noncoding RNAs
inferred← citeshttps://doi.org/10.1016/b978-0-12-404740-2.00010-0openalex-snapshot
The Diverse Functions of Fungal RNase III Enzymes in RNA Metabolism
inferred← citeshttps://doi.org/10.1016/b978-0-12-404741-9.00001-5openalex-snapshot
Dicer Proteins and Their Role in Gene Silencing Pathways
inferred← citeshttps://doi.org/10.1016/b978-0-12-404741-9.00002-7openalex-snapshot
Loquacious, a Dicer Partner Protein, Functions in Both the MicroRNA and siRNA Pathways
inferred← citeshttps://doi.org/10.1016/b978-0-12-404741-9.00004-0openalex-snapshot
Structure and Mechanism of Argonaute Proteins
inferred← citeshttps://doi.org/10.1016/b978-0-12-404741-9.00005-2openalex-snapshot
Drosha and DGCR8 in MicroRNA Biogenesis
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.12424-2openalex-snapshot
Current Progress and Future Prospects in Nucleic Acid Based Therapeutics
inferred← citeshttps://doi.org/10.1016/b978-0-12-800178-3.00005-1openalex-snapshot
Biological Mechanisms Determining the Success of RNA Interference in Insects
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.95612-5openalex-snapshot
Physiological and Pathological Functions of Mammalian MicroRNAs
inferred← citeshttps://doi.org/10.1016/b978-0-12-804402-5.00001-7openalex-snapshot
Making and Maintaining microRNAs in Animals
inferred← citeshttps://doi.org/10.1016/b978-0-12-811022-5.00003-6openalex-snapshot
Alteration of MicroRNA Biogenesis Pathways in Cancers
inferred← citeshttps://doi.org/10.1016/b978-0-12-821618-7.00096-1openalex-snapshot
miRNAs/Small Noncoding RNAs
inferred← citeshttps://doi.org/10.1016/b978-0-12-821843-3.00008-8openalex-snapshot
RNA interference as a promising strategy for plant disease management
inferred← citeshttps://doi.org/10.1016/b978-0-323-89774-7.00010-8openalex-snapshot
Maturation of microRNAs
inferred← citeshttps://doi.org/10.1016/b978-0-323-90053-9.00003-8openalex-snapshot
miRNAs: the genetic regulators of immunity
inferred← citeshttps://doi.org/10.1016/b978-0-323-95375-7.00011-2openalex-snapshot
Role of miRNAs in the cross-talk of phytohormone signaling pathways
inferred← citeshttps://doi.org/10.1016/b978-0-323-98803-2.00011-0openalex-snapshot
Function of membrane and protein synthesis in the cell
inferred← citeshttps://doi.org/10.1016/b978-0-443-44585-9.00004-4openalex-snapshot
Overcoming drug resistance in nonsmall cell lung cancer: Small interfering RNAs-guided gene silencing combined with cisplatin therapy
inferred← citeshttps://doi.org/10.1016/bs.aiip.2017.02.002openalex-snapshot
The Role of MicroRNAs in Drosophila Regulation of Insulin-Like Peptides and Ecdysteroid Signalling: Where Are We Now?
inferred← citeshttps://doi.org/10.1016/bs.apar.2019.12.002openalex-snapshot
Recent advances in functional research in Giardia intestinalis
inferred← citeshttps://doi.org/10.1016/bs.mie.2023.02.023openalex-snapshot
The pre-miRNA cleavage assays for DICER
inferred← citeshttps://doi.org/10.1016/j.addr.2007.03.003openalex-snapshot
Non-viral siRNA delivery to the lung
inferred← citeshttps://doi.org/10.1016/j.addr.2009.03.004openalex-snapshot
Lentiviral delivery of short hairpin RNAs
inferred← citeshttps://doi.org/10.1016/j.addr.2009.04.004openalex-snapshot
siRNA vs. shRNA: Similarities and differences
inferred← citeshttps://doi.org/10.1016/j.addr.2011.01.006openalex-snapshot
RNA interference therapy via functionalized scaffolds
inferred← citeshttps://doi.org/10.1016/j.addr.2012.06.005openalex-snapshot
Reprogrammed cell delivery for personalized medicine
inferred← citeshttps://doi.org/10.1016/j.ajps.2018.12.005openalex-snapshot
Design, mechanism, delivery and therapeutics of canonical and Dicer-substrate siRNA
inferred← citeshttps://doi.org/10.1016/j.antiviral.2020.104916openalex-snapshot
Enzymatically synthesized 2′-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity
inferred← citeshttps://doi.org/10.1016/j.arr.2014.07.001openalex-snapshot
The mitochondrial genome in aging and senescence
inferred← citeshttps://doi.org/10.1016/j.bbadis.2021.166314openalex-snapshot
An emerging role of the 5′ termini of mature tRNAs in human diseases: Current situation and prospects
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2008.10.002openalex-snapshot
Human Dicer C-terminus functions as a 5-lipoxygenase binding domain
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2009.05.006openalex-snapshot
A structural perspective of the protein–RNA interactions involved in virus-induced RNA silencing and its suppression
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2013.03.009openalex-snapshot
Intracellular ribonucleases involved in transcript processing and decay: Precision tools for RNA
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2016.02.014openalex-snapshot
siRNA release from pri-miRNA scaffolds is controlled by the sequence and structure of RNA
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2024.195046openalex-snapshot
Incautious design of shRNAs for stable overexpression of miRNAs could result in generation of undesired isomiRs
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2013.06.017openalex-snapshot
Regulation of RNA interference by Hsp90 is an evolutionarily conserved process
inferred← citeshttps://doi.org/10.1016/j.bbapap.2014.07.001openalex-snapshot
Helicase associated 2 domain is essential for helicase activity of RNA helicase A
inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.10.116openalex-snapshot
Chemically modified symmetric and asymmetric duplex RNAs: An enhanced stability to nuclease degradation and gene silencing effect
inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.04.118openalex-snapshot
Functional analysis of dicer-2 missense mutations in the siRNA pathway of Drosophila
inferred← citeshttps://doi.org/10.1016/j.bbrc.2012.07.047openalex-snapshot
The regulatory roles of miRNA and methylation on oncogene and tumor suppressor gene expression in pancreatic cancer cells
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