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The SOS Response Controls Integron Recombination

https://doi.org/10.1126/science.1172914
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.mib.2006.07.002openalex-snapshot
The biological cost of mutational antibiotic resistance: any practical conclusions?
inferredcites →https://doi.org/10.1016/j.tim.2006.08.006openalex-snapshot
Upstream of the SOS response: figure out the trigger
inferredcites →https://doi.org/10.1038/nrmicro1462openalex-snapshot
Integrons: agents of bacterial evolution
inferredcites →https://doi.org/10.1111/j.1574-6976.2007.00082.xopenalex-snapshot
Aeons of distress: an evolutionary perspective on the bacterial SOS response
inferredcites →https://doi.org/10.1128/aac.39.1.155openalex-snapshot
Expression of antibiotic resistance genes in the integrated cassettes of integrons

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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The Peril and Promise of Integrons: Beyond Antibiotic Resistance
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Hospital and urban wastewaters shape the matrix and active resistome of environmental biofilms
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Temporal dynamics of class 1 and class 3 integron pools in treated wastewater
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Resistencia a los antibióticos y unidad de cuidados críticos
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River Networks as Ecological Corridors
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Preface
inferred← citeshttps://doi.org/10.1017/9781108775014.002openalex-snapshot
Introduction
inferred← citeshttps://doi.org/10.1017/9781108775014.003openalex-snapshot
Species
inferred← citeshttps://doi.org/10.1017/9781108775014.004openalex-snapshot
Populations
inferred← citeshttps://doi.org/10.1017/9781108775014.005openalex-snapshot
Waterborne Disease
inferred← citeshttps://doi.org/10.1017/9781108775014.006openalex-snapshot
Afterthoughts and Outlook
inferred← citeshttps://doi.org/10.1017/9781108775014.007openalex-snapshot
Appendices
inferred← citeshttps://doi.org/10.1017/9781108775014.008openalex-snapshot
Index
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Targets for Combating the Evolution of Acquired Antibiotic Resistance
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Type- and Treatment Duration-Dependent Efficacy of Metal–Organic Frameworks for Combating Antibiotic Resistance Genes in Real Wastewater
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Influence of Manure Application on the Environmental Resistome under Finnish Agricultural Practice with Restricted Antibiotic Use
inferred← citeshttps://doi.org/10.1021/acsinfecdis.7b00122openalex-snapshot
Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic–Industry Partnership
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Specificity Determinants for Autoproteolysis of LexA, a Key Regulator of Bacterial SOS Mutagenesis
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Dynamic Assessment of the Floc Morphology, Bacterial Diversity, and Integron Content of an Activated Sludge Reactor Processing Hospital Effluent
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Cellular pathways controlling integron cassette site folding
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Erratum to: Cellular pathways controlling integron cassette site folding
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Coral-mucus-associated Vibrio integrons in the Great Barrier Reef: genomic hotspots for environmental adaptation
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Impacts of anthropogenic activity on the ecology of class 1 integrons and integron-associated genes in the environment
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Quantitative and qualitative impact of hospital effluent on dissemination of the integron pool
inferred← citeshttps://doi.org/10.1038/ismej.2015.222openalex-snapshot
The evolutionary dynamics of integrons in changing environments
inferred← citeshttps://doi.org/10.1038/ismej.2017.38openalex-snapshot
Class 1 integrons are low-cost structures in Escherichia coli
inferred← citeshttps://doi.org/10.1038/ja.2010.137openalex-snapshot
Modulation of Salmonella gene expression by subinhibitory concentrations of quinolones
inferred← citeshttps://doi.org/10.1038/ncomms10937openalex-snapshot
Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
inferred← citeshttps://doi.org/10.1038/npjbiofilms.2016.22openalex-snapshot
Plasmid transfer in biofilms: a perspective on limitations and opportunities
inferred← citeshttps://doi.org/10.1038/nrmicro2192openalex-snapshot
In Brief
inferred← citeshttps://doi.org/10.1038/nrmicro2333openalex-snapshot
How antibiotics kill bacteria: from targets to networks
inferred← citeshttps://doi.org/10.1038/s41396-022-01249-0openalex-snapshot
Protozoal food vacuoles enhance transformation in Vibrio cholerae through SOS-regulated DNA integration
inferred← citeshttps://doi.org/10.1038/s41467-024-50917-6openalex-snapshot
RNA polymerase stalling-derived genome instability underlies ribosomal antibiotic efficacy and resistance evolution
inferred← citeshttps://doi.org/10.1038/s41467-024-53525-6openalex-snapshot
The expression of integron arrays is shaped by the translation rate of cassettes
inferred← citeshttps://doi.org/10.1038/s41564-021-00930-yopenalex-snapshot
Single-molecule imaging of LexA degradation in Escherichia coli elucidates regulatory mechanisms and heterogeneity of the SOS response
inferred← citeshttps://doi.org/10.1038/s41564-023-01548-yopenalex-snapshot
Integron cassettes integrate into bacterial genomes via widespread non-classical attG sites
inferred← citeshttps://doi.org/10.1038/s41598-017-00600-2openalex-snapshot
Lateral Antimicrobial Resistance Genetic Transfer is active in the open environment
inferred← citeshttps://doi.org/10.1038/s41598-017-17640-3openalex-snapshot
Genetic adaptation of microbial populations present in high-intensity catfish production systems with therapeutic oxytetracycline treatment
inferred← citeshttps://doi.org/10.1038/s41598-018-21841-9openalex-snapshot
Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments
inferred← citeshttps://doi.org/10.1038/s41598-018-25474-wopenalex-snapshot
Acquisition and dissemination of cephalosporin-resistant E. coli in migratory birds sampled at an Alaska landfill as inferred through genomic analysis
inferred← citeshttps://doi.org/10.1038/s41598-019-44640-2openalex-snapshot
Promoter activity of ORF-less gene cassettes isolated from the oral metagenome
inferred← citeshttps://doi.org/10.1038/s41598-020-77377-4openalex-snapshot
Integron gene cassettes harboring novel variants of d-alanine-d-alanine ligase confer high-level resistance to d-cycloserine
inferred← citeshttps://doi.org/10.1038/s41598-023-35074-yopenalex-snapshot
Sub-inhibitory gentamicin pollution induces gentamicin resistance gene integration in class 1 integrons in the environment
inferred← citeshttps://doi.org/10.1038/s42003-021-02489-0openalex-snapshot
Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
inferred← citeshttps://doi.org/10.1038/s42003-026-09788-4openalex-snapshot
Mechanistic insights into the structure and function of the RecA C-terminal tail
inferred← citeshttps://doi.org/10.1038/srep24645openalex-snapshot
Characterization of the resistome in manure, soil and wastewater from dairy and beef production systems
inferred← citeshttps://doi.org/10.1039/c7ra07303hopenalex-snapshot
The mode of antimicrobial action of curcumin depends on the delivery system: monolithic nanoparticles vs. supramolecular inclusion complex
inferred← citeshttps://doi.org/10.1039/d6en00454gopenalex-snapshot
Nanotechnology-based strategies for environmental control of antimicrobial resistance
inferred← citeshttps://doi.org/10.1051/medsci/201026128openalex-snapshot
Les antibiotiques induisent la capture de gènes de résistance par les bactéries
inferred← citeshttps://doi.org/10.1051/medsci/2012282016openalex-snapshot
Antibiotiques et réponse SOS bactérienne
inferred← citeshttps://doi.org/10.1051/medsci/2026026openalex-snapshot
Les intégrons, architectes de la défense bactérienne contre les phages
inferred← citeshttps://doi.org/10.1057/s41599-019-0251-8openalex-snapshot
Antimicrobials before antibiotics: war, peace, and disinfectants
inferred← citeshttps://doi.org/10.1071/ma10158openalex-snapshot
Biocides in the health industry
inferred← citeshttps://doi.org/10.1071/ma10192openalex-snapshot
Biocide use, integrons and novel genetic elements
inferred← citeshttps://doi.org/10.1073/pnas.1203333109openalex-snapshot
Reassessment of the 2010–2011 Haiti cholera outbreak and rainfall-driven multiseason projections
inferred← citeshttps://doi.org/10.1073/pnas.1907567116openalex-snapshot
Sublethal antibiotics collapse gut bacterial populations by enhancing aggregation and expulsion
inferred← citeshttps://doi.org/10.1080/10408398.2010.519837openalex-snapshot
Antibiotic-Resistant Bacteria: A Challenge for the Food Industry
inferred← citeshttps://doi.org/10.1080/10408398.2015.1077192openalex-snapshot
Antimicrobial resistance: A global emerging threat to public health systems
inferred← citeshttps://doi.org/10.1080/1040841x.2021.1907301openalex-snapshot
The equine hindgut as a reservoir of mobile genetic elements and antimicrobial resistance genes
inferred← citeshttps://doi.org/10.1080/1040841x.2024.2412007openalex-snapshot
Exploring the antibiotic resistance of Listeria monocytogenes in food environments – a review
inferred← citeshttps://doi.org/10.1080/10643389.2022.2085956openalex-snapshot
Framework for establishing regulatory guidelines to control antibiotic resistance in treated effluents
inferred← citeshttps://doi.org/10.1089/mdr.2012.0115openalex-snapshot
Antibiotic Resistance: From Darwin to Lederberg to Keynes
inferred← citeshttps://doi.org/10.1093/bioinformatics/btt753openalex-snapshot
Characterization of the SOS meta-regulon in the human gut microbiome
inferred← citeshttps://doi.org/10.1093/etojnl/vgag089openalex-snapshot
Beyond the chemical load: Wastewater residuals as drivers of antibiotic resistance proliferation and dissemination into soil, water, and food webs
inferred← citeshttps://doi.org/10.1093/femsre/fuae017openalex-snapshot
Unravelling the mechanisms of antibiotic and heavy metal resistance co-selection in environmental bacteria
inferred← citeshttps://doi.org/10.1093/ismeco/ycaf169openalex-snapshot
Common non-antibiotic drugs enhance selection for antimicrobial resistance in mixture with ciprofloxacin
inferred← citeshttps://doi.org/10.1093/ismeco/ycag140openalex-snapshot
Selective shifts in mobile antibiotic resistance genes under carbamazepine exposure in wastewater microbiomes
inferred← citeshttps://doi.org/10.1093/ismejo/wrae014openalex-snapshot
Protozoan predation enhances stress resistance and antibiotic tolerance in Burkholderia cenocepacia by triggering the SOS response
inferred← citeshttps://doi.org/10.1093/ismejo/wraf009openalex-snapshot
Protozoa-enhanced conjugation frequency alters the dissemination of soil antibiotic resistance
inferred← citeshttps://doi.org/10.1093/jac/dkab045openalex-snapshot
Expression of the qepA1 gene is induced under antibiotic exposure
inferred← citeshttps://doi.org/10.1093/jac/dkab450openalex-snapshot
Antimicrobial-induced horizontal transfer of antimicrobial resistance genes in bacteria: a mini-review
inferred← citeshttps://doi.org/10.1093/jac/dkaf068openalex-snapshot
Antibiotic-induced stress responses in Gram-negative bacteria and their role in antibiotic resistance
inferred← citeshttps://doi.org/10.1093/jac/dkq167openalex-snapshot
Quantitative multiplex real-time PCR for detecting class 1, 2 and 3 integrons
inferred← citeshttps://doi.org/10.1093/jac/dks196openalex-snapshot
Bacterial stress responses as determinants of antimicrobial resistance
inferred← citeshttps://doi.org/10.1093/jac/dkx202openalex-snapshot
Inducibility of Tn916 conjugative transfer in Enterococcus faecalis by subinhibitory concentrations of ribosome-targeting antibiotics
inferred← citeshttps://doi.org/10.1093/nar/gkab412openalex-snapshot
Cassette recruitment in the chromosomal Integron of Vibrio cholerae
inferred← citeshttps://doi.org/10.1093/nar/gkac662openalex-snapshot
The expression of aminoglycoside resistance genes in integron cassettes is not controlled by riboswitches
inferred← citeshttps://doi.org/10.1093/nar/gkae243openalex-snapshot
RecA-dependent or independent recombination of plasmid DNA generates a conflict with the host EcoKI immunity by launching restriction alleviation
inferred← citeshttps://doi.org/10.1093/nar/gkae866openalex-snapshot
Chromosomal integrons are genetically and functionally isolated units of genomes
inferred← citeshttps://doi.org/10.1093/nar/gkaf1162openalex-snapshot
Bacterial natural transformation drives cassette shuffling and simplifies recombination in chromosomal integrons
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