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Landscape of Somatic Retrotransposition in Human Cancers

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/humu.20307openalex-snapshot
dbRIP: A highly integrated database of retrotransposon insertion polymorphisms in humans
inferredcites →https://doi.org/10.1007/s00018-008-8494-3openalex-snapshot
Endogenous retroviruses
inferredcites →https://doi.org/10.1016/j.ccr.2010.03.020openalex-snapshot
PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas
inferredcites →https://doi.org/10.1016/j.cell.2010.05.020openalex-snapshot
Natural Mutagenesis of Human Genomes by Endogenous Retrotransposons
inferredcites →https://doi.org/10.1016/j.cell.2010.05.021openalex-snapshot
LINE-1 Retrotransposition Activity in Human Genomes
inferredcites →https://doi.org/10.1016/j.cell.2010.10.027openalex-snapshot
A Human Genome Structural Variation Sequencing Resource Reveals Insights into Mutational Mechanisms
inferredcites →https://doi.org/10.1016/j.cell.2011.08.016openalex-snapshot
Sperm Methylation Profiles Reveal Features of Epigenetic Inheritance and Evolution in Primates
inferredcites →https://doi.org/10.1016/j.gde.2012.02.006openalex-snapshot
Active human retrotransposons: variation and disease
inferredcites →https://doi.org/10.1016/j.gene.2009.05.014openalex-snapshot
Internal priming: An opportunistic pathway for L1 and Alu retrotransposition in hominins
inferredcites →https://doi.org/10.1016/j.tig.2007.02.006openalex-snapshot
Which transposable elements are active in the human genome?
inferredcites →https://doi.org/10.1021/bi981858sopenalex-snapshot
Targeting of Human Retrotransposon Integration Is Directed by the Specificity of the L1 Endonuclease for Regions of Unusual DNA Structure
inferredcites →https://doi.org/10.1038/35038572openalex-snapshot
Mobile elements and the human genome
inferredcites →https://doi.org/10.1038/nature02536openalex-snapshot
Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes
inferredcites →https://doi.org/10.1038/nature02886openalex-snapshot
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L
inferredcites →https://doi.org/10.1038/nature09744openalex-snapshot
The genomic complexity of primary human prostate cancer
inferredcites →https://doi.org/10.1038/nature09837openalex-snapshot
Initial genome sequencing and analysis of multiple myeloma
inferredcites →https://doi.org/10.1038/nature09906openalex-snapshot
Mapping and analysis of chromatin state dynamics in nine human cell types
inferredcites →https://doi.org/10.1038/nature10531openalex-snapshot
Somatic retrotransposition alters the genetic landscape of the human brain
inferredcites →https://doi.org/10.1038/ng.969openalex-snapshot
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains
inferredcites →https://doi.org/10.1038/ng898openalex-snapshot
DNA repair mediated by endonuclease-independent LINE-1 retrotransposition
inferredcites →https://doi.org/10.1038/nmeth.1628openalex-snapshot
CREST maps somatic structural variation in cancer genomes with base-pair resolution
inferredcites →https://doi.org/10.1038/nrg2072openalex-snapshot
Transposable elements and the epigenetic regulation of the genome
inferredcites →https://doi.org/10.1038/nsmb1141openalex-snapshot
L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells
inferredcites →https://doi.org/10.1038/sj.onc.1205651openalex-snapshot
DNA methylation in cancer: too much, but also too little
inferredcites →https://doi.org/10.1038/sj.onc.1210461openalex-snapshot
Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma
inferredcites →https://doi.org/10.1038/sj.onc.1210631openalex-snapshot
Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice
inferredcites →https://doi.org/10.1073/pnas.0710052104openalex-snapshot
Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
inferredcites →https://doi.org/10.1073/pnas.1009941107openalex-snapshot
PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice
inferredcites →https://doi.org/10.1093/hmg/ddi092openalex-snapshot
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers
inferredcites →https://doi.org/10.1093/hmg/ddr245openalex-snapshot
Retrotransposition of marked SVA elements by human L1s in cultured cells
inferredcites →https://doi.org/10.1093/nar/gkp335openalex-snapshot
MEME SUITE: tools for motif discovery and searching
inferredcites →https://doi.org/10.1093/nar/gkr863openalex-snapshot
The non-autonomous retrotransposon SVA is trans -mobilized by the human LINE-1 protein machinery
inferredcites →https://doi.org/10.1101/gr.106419.110openalex-snapshot
High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes
inferredcites →https://doi.org/10.1101/gr.114777.110openalex-snapshot
Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans
inferredcites →https://doi.org/10.1101/gr.115956.110openalex-snapshot
Alu repeat discovery and characterization within human genomes
inferredcites →https://doi.org/10.1101/gr.121541.111openalex-snapshot
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
inferredcites →https://doi.org/10.1101/gr.9.9.868openalex-snapshot
CAP3: A DNA Sequence Assembly Program
inferredcites →https://doi.org/10.1111/j.1349-7006.2009.01185.xopenalex-snapshot
Involvement of G‐patch domain containing 2 overexpression in breast carcinogenesis
inferredcites →https://doi.org/10.1155/jbb/2006/75327openalex-snapshot
The Genomic Distribution of L1 Elements: The Role of Insertion Bias and Natural Selection
inferredcites →https://doi.org/10.1158/1078-0432.ccr-10-1071openalex-snapshot
Molecular Karyotypes of Hodgkin and Reed–Sternberg Cells at Disease Onset Reveal Distinct Copy Number Alterations in Chemosensitive versus Refractory Hodgkin Lymphoma
inferredcites →https://doi.org/10.1159/000084979openalex-snapshot
Repbase Update, a database of eukaryotic repetitive elements
inferredcites →https://doi.org/10.1186/gb-2010-11-6-r69openalex-snapshot
Estimating enrichment of repetitive elements from high-throughput sequence data
inferredcites →https://doi.org/10.1371/journal.pgen.1000327openalex-snapshot
A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation
inferredcites →https://doi.org/10.1371/journal.pgen.1002236openalex-snapshot
A Comprehensive Map of Mobile Element Insertion Polymorphisms in Humans
inferredcites →https://doi.org/10.1371/journal.pone.0027792openalex-snapshot
Glucocorticoid Regulation of SLIT/ROBO Tumour Suppressor Genes in the Ovarian Surface Epithelium and Ovarian Cancer Cells

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3245216openalex-extracted
MSH2 is Inactivated by Multiple Mechanisms in Prostate Tumors, Leading to a Distinct Immune Response and Clinical Outcome Compared to MSH2 Deficient Colorectal Cancer
inferred← citeshttps://doi.org/10.1002/1873-3468.13260openalex-snapshot
SOX ‐11 regulates LINE ‐1 retrotransposon activity during neuronal differentiation
inferred← citeshttps://doi.org/10.1002/1878-0261.70111openalex-snapshot
Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies
inferred← citeshttps://doi.org/10.1002/9780470015902.a0020837openalex-snapshot
Recently Mobilised Transposons in the Human Genome
inferred← citeshttps://doi.org/10.1002/9780470015902.a0024377openalex-snapshot
Mobile Elements in the Human Genome: Implications for Disease
inferred← citeshttps://doi.org/10.1002/ajmg.b.32225openalex-snapshot
Transposable elements and psychiatric disorders
inferred← citeshttps://doi.org/10.1002/bies.201200133openalex-snapshot
How do mammalian transposons induce genetic variation? A conceptual framework
inferred← citeshttps://doi.org/10.1002/bies.201300049openalex-snapshot
Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis
inferred← citeshttps://doi.org/10.1002/bies.201300097openalex-snapshot
Death by transposition – the enemy within?
inferred← citeshttps://doi.org/10.1002/bies.201300130openalex-snapshot
DNA methylation reprogramming in cancer: Does it act by re‐configuring the binding landscape of Polycomb repressive complexes?
inferred← citeshttps://doi.org/10.1002/bies.201300181openalex-snapshot
Diversity through duplication: Whole‐genome sequencing reveals novel gene retrocopies in the human population
inferred← citeshttps://doi.org/10.1002/bies.201600031openalex-snapshot
P53 and the defenses against genome instability caused by transposons and repetitive elements
inferred← citeshttps://doi.org/10.1002/bies.201700189openalex-snapshot
Heritable L1 Retrotransposition Events During Development: Understanding Their Origins
inferred← citeshttps://doi.org/10.1002/bies.201800058openalex-snapshot
Surveillance of Retroelement Expression and Nucleic‐Acid Immunity by Histone Methyltransferase SETDB1
inferred← citeshttps://doi.org/10.1002/bies.201900197openalex-snapshot
Transposable Elements Cross Kingdom Boundaries and Contribute to Inflammation and Ageing
inferred← citeshttps://doi.org/10.1002/bies.201900232openalex-snapshot
What Doesn't Kill You Makes You Stronger: Transposons as Dual Players in Chromatin Regulation and Genomic Variation
inferred← citeshttps://doi.org/10.1002/bies.202100242openalex-snapshot
Nucleic acids movement and its relation to genome dynamics of repetitive DNA
inferred← citeshttps://doi.org/10.1002/bies.70078openalex-snapshot
Revisiting Clonal Evolution Through the Light of Retrotransposons
inferred← citeshttps://doi.org/10.1002/cne.24046openalex-snapshot
Epigenetic mechanisms and associated brain circuits in the regulation of positive emotions: A role for transposable elements
inferred← citeshttps://doi.org/10.1002/cphg.102openalex-snapshot
Identification and Genotyping of Transposable Element Insertions From Genome Sequencing Data
inferred← citeshttps://doi.org/10.1002/cphg.103openalex-snapshot
A Practical Guide for Structural Variation Detection in the Human Genome
inferred← citeshttps://doi.org/10.1002/cpz1.206openalex-snapshot
RepExpress: A Novel Pipeline for the Quantification and Characterization of Transposable Element Expression from RNA‐seq Data
inferred← citeshttps://doi.org/10.1002/dneu.22567openalex-snapshot
LINE‐1 retrotransposons in healthy and diseased human brain
inferred← citeshttps://doi.org/10.1002/dneu.22626openalex-snapshot
Genomic mosaicism in the developing and adult brain
inferred← citeshttps://doi.org/10.1002/dvg.70031openalex-snapshot
ATRX : From Chromatin Remodeling to Disease
inferred← citeshttps://doi.org/10.1002/eji.201344322openalex-snapshot
Insertional hypermutation in mineral oil‐induced plasmacytomas
inferred← citeshttps://doi.org/10.1002/em.22366openalex-snapshot
Long INterspersed element‐1 mobility as a sensor of environmental stresses
inferred← citeshttps://doi.org/10.1002/gcc.22954openalex-snapshot
Transposable element insertion as a mechanism of SMARCB1 inactivation in atypical teratoid/rhabdoid tumor
inferred← citeshttps://doi.org/10.1002/humu.22953openalex-snapshot
Germline Chromothripsis Driven by L1-Mediated Retrotransposition and Alu/Alu Homologous Recombination
inferred← citeshttps://doi.org/10.1002/humu.23027openalex-snapshot
Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.1002/humu.23608openalex-snapshot
LINE- andAlu-containing genomic instability hotspot at 16q24.1 associated with recurrent and nonrecurrent CNV deletions causative for ACDMPV
inferred← citeshttps://doi.org/10.1002/iub.70077openalex-snapshot
Silent Guardians Gone Rogue: The Role of PIWI and piRNA in Malignant Transformation
inferred← citeshttps://doi.org/10.1002/mco2.70472openalex-snapshot
Exosomal Long Interspersed Nuclear Element‐1 Analytes Discriminate Histologic Subtypes, Sex, and Clinicopathological Characteristics of Patients with Non‐Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.1002/mco2.790openalex-snapshot
Multifaceted role of TRIM28 in health and disease
inferred← citeshttps://doi.org/10.1002/path.5755openalex-snapshot
Optical genome mapping identifies a germline retrotransposon insertion in SMARCB1 in two siblings with atypical teratoid rhabdoid tumors
inferred← citeshttps://doi.org/10.1002/path.6371openalex-snapshot
LINE ‐1 hypomethylation characterizes the inflammatory response in coeliac disease associated‐intestinal mucosa and small bowel adenocarcinomas
inferred← citeshttps://doi.org/10.1002/rmv.2142openalex-snapshot
The role of endogenous retroviruses‐K in human cancer
inferred← citeshttps://doi.org/10.1007/82_2015_442openalex-snapshot
Pseudogene-Expressed RNAs: Emerging Roles in Gene Regulation and Disease
inferred← citeshttps://doi.org/10.1007/978-1-4939-1804-1_10openalex-snapshot
Epigenetics of Urothelial Carcinoma
inferred← citeshttps://doi.org/10.1007/978-1-4939-3372-3_1openalex-snapshot
Study of Transposable Elements and Their Genomic Impact
inferred← citeshttps://doi.org/10.1007/978-1-4939-3372-3_19openalex-snapshot
Purification of L1-Ribonucleoprotein Particles (L1-RNPs) from Cultured Human Cells
inferred← citeshttps://doi.org/10.1007/978-1-4939-3372-3_24openalex-snapshot
Profiling DNA Methylation and Hydroxymethylation at Retrotransposable Elements
inferred← citeshttps://doi.org/10.1007/978-1-4939-3372-3_5openalex-snapshot
Long Interspersed Element Sequencing (L1-Seq): A Method to Identify Somatic LINE-1 Insertions in the Human Genome
inferred← citeshttps://doi.org/10.1007/978-1-4939-7710-9_11openalex-snapshot
Analysis of RNA-Seq Data Using TEtranscripts
inferred← citeshttps://doi.org/10.1007/978-1-4939-7768-0_4openalex-snapshot
CpG Islands in Cancer: Heads, Tails, and Sides
inferred← citeshttps://doi.org/10.1007/978-1-4939-9004-7_15openalex-snapshot
High-Throughput Targeted Repeat Element Bisulfite Sequencing (HT-TREBS)
inferred← citeshttps://doi.org/10.1007/978-1-4939-9074-0_6openalex-snapshot
Transposable Elements: Classification, Identification, and Their Use As a Tool For Comparative Genomics
inferred← citeshttps://doi.org/10.1007/978-3-031-16286-2_2openalex-snapshot
Cancer Genetics
inferred← citeshttps://doi.org/10.1007/978-3-031-42806-7_2openalex-snapshot
Krebsgenetik
inferred← citeshttps://doi.org/10.1007/978-3-032-04125-8_4openalex-snapshot
Epigenetic Control of Transposable Elements
inferred← citeshttps://doi.org/10.1007/978-3-032-12166-0_10openalex-snapshot
Cell-Free DNA (cfDNA), Its Applications in Cancer Diagnosis and Monitoring, and Its Potential Role in Regulating Cancer Metabolism
inferred← citeshttps://doi.org/10.1007/978-3-319-19932-0_6openalex-snapshot
The Impact of Transposable Elements in the Evolution of Plant Genomes: From Selfish Elements to Key Players
inferred← citeshttps://doi.org/10.1007/978-3-319-48344-3_11openalex-snapshot
Retrotransposon-Driven Transcription and Cancer
inferred← citeshttps://doi.org/10.1007/978-3-319-48344-3_12openalex-snapshot
LINE-1 Retrotransposons as Neoplastic Biomarkers
inferred← citeshttps://doi.org/10.1007/978-3-319-48344-3_3openalex-snapshot
Retrotransposon Contribution to Genomic Plasticity
inferred← citeshttps://doi.org/10.1007/978-3-319-48344-3_6openalex-snapshot
Activity of Retrotransposons in Stem Cells and Differentiated Cells
inferred← citeshttps://doi.org/10.1007/978-3-319-48344-3_7openalex-snapshot
Environment, Cellular Signaling, and L1 Activity
inferred← citeshttps://doi.org/10.1007/978-3-319-64543-8_1openalex-snapshot
Circadian Dysregulation and Melatonin Rhythm Suppression in the Context of Aging
inferred← citeshttps://doi.org/10.1007/978-3-642-31974-7_9openalex-snapshot
Epigenetic Reprogramming in Cancer
inferred← citeshttps://doi.org/10.1007/978-94-017-9639-2_3openalex-snapshot
LINE-1 Retrotransposons and Their Role in Cancer
inferred← citeshttps://doi.org/10.1007/978-981-97-1777-4_20openalex-snapshot
Trends Innovations Challenges in Employing Interdisciplinary Approaches to Biomedical Sciences
inferred← citeshttps://doi.org/10.1007/978-981-99-7074-2_13openalex-snapshot
ricME: Long-Read Based Mobile Element Variant Detection Using Sequence Realignment and Identity Calculation
inferred← citeshttps://doi.org/10.1007/s00018-015-1947-6openalex-snapshot
Molecular functions of human endogenous retroviruses in health and disease
inferred← citeshttps://doi.org/10.1007/s00239-019-09911-6openalex-snapshot
An Evolutionary Perspective on the Impact of Genomic Copy Number Variation on Human Health
inferred← citeshttps://doi.org/10.1007/s00294-016-0592-4openalex-snapshot
Potential movement of transposable elements through DNA circularization
inferred← citeshttps://doi.org/10.1007/s00439-021-02365-1openalex-snapshot
Evaluation of copy number variants for genetic hearing loss: a review of current approaches and recent findings
inferred← citeshttps://doi.org/10.1007/s00705-023-05747-0openalex-snapshot
HERV-K (HML-2) insertion polymorphisms in the 8q24.13 region and their potential etiological associations with acute myeloid leukemia
inferred← citeshttps://doi.org/10.1007/s10522-023-10028-zopenalex-snapshot
The role of transposable elements in aging and cancer
inferred← citeshttps://doi.org/10.1007/s11101-019-09627-xopenalex-snapshot
Phytochemicals in cancer prevention: modulating epigenetic alterations of DNA methylation
inferred← citeshttps://doi.org/10.1007/s12011-014-0015-7openalex-snapshot
Evaluating the Extent of LINE-1 Mobility Following Exposure to Heavy Metals in HepG2 Cells
inferred← citeshttps://doi.org/10.1007/s12011-015-0298-3openalex-snapshot
Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage
inferred← citeshttps://doi.org/10.1007/s12094-020-02424-5openalex-snapshot
Efavirenz as a potential drug for the treatment of triple-negative breast cancers
inferred← citeshttps://doi.org/10.1007/s12539-023-00563-1openalex-snapshot
A Self-attention Graph Convolutional Network for Precision Multi-tumor Early Diagnostics with DNA Methylation Data
inferred← citeshttps://doi.org/10.1007/s13258-014-0256-zopenalex-snapshot
Biological changes of transposable elements by radiation: recent progress
inferred← citeshttps://doi.org/10.1007/s13258-024-01546-2openalex-snapshot
Epigenetic regulation of HERVs: Implications for cancer immunotherapy
inferred← citeshttps://doi.org/10.1007/s40291-026-00861-6openalex-snapshot
LINE-1 Deregulation in Ovarian Cancer: Implications for Diagnosis, Prognosis, and Therapeutic Targeting
inferred← citeshttps://doi.org/10.1007/s41745-016-0018-9openalex-snapshot
Spatio-Temporal Control of Cellular and Organismal Physiology by Sirtuins
inferred← citeshttps://doi.org/10.1016/b978-0-12-394447-4.10044-6openalex-snapshot
Small RNAs/Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-800206-3.00024-0openalex-snapshot
Genetic Intratumor Heterogeneity
inferred← citeshttps://doi.org/10.1016/b978-0-12-800563-7.00005-1openalex-snapshot
Risks of Insertional Mutagenesis by DNA Transposons in Cancer Gene Therapy
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.01922-xopenalex-snapshot
Long Interspersed Nuclear Element (LINE-1/L1)
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.99175-xopenalex-snapshot
Genetic and Epigenetic Determinants of Environmental Injury and Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-801596-4.00007-1openalex-snapshot
Measuring CpG Methylation by SMRT Sequencing
inferred← citeshttps://doi.org/10.1016/b978-0-12-801899-6.00014-0openalex-snapshot
DNA Methylation Alterations as Biomarkers for Prostate Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-809633-8.20227-6openalex-snapshot
Repeat in Genomes: How and Why You Should Consider Them in Genome Analyses?
inferred← citeshttps://doi.org/10.1016/b978-0-12-821618-7.10044-6openalex-snapshot
Small RNAs/Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-823761-8.00027-6openalex-snapshot
The epigenetics of aging
inferred← citeshttps://doi.org/10.1016/b978-0-12-824010-6.00059-9openalex-snapshot
Transformer-based modeling to study repetitive sequences of the human genome
inferred← citeshttps://doi.org/10.1016/b978-0-323-95502-7.00066-xopenalex-snapshot
Repeats in Genomes
inferred← citeshttps://doi.org/10.1016/b978-0-443-13963-5.00011-xopenalex-snapshot
“Multiomics in precision medicine”
inferred← citeshttps://doi.org/10.1016/bs.adgen.2025.11.004openalex-snapshot
Transposable elements in human cancer: Regulation, activation, and genomic consequences
inferred← citeshttps://doi.org/10.1016/j.ajpath.2014.01.007openalex-snapshot
Long Interspersed Element-1 Protein Expression Is a Hallmark of Many Human Cancers
inferred← citeshttps://doi.org/10.1016/j.ajpath.2018.11.005openalex-snapshot
Long Interspersed Nuclear Element 1 Retrotransposons Become Deregulated during the Development of Ovarian Cancer Precursor Lesions
inferred← citeshttps://doi.org/10.1016/j.arcmed.2022.11.011openalex-snapshot
Cancer Genomics
inferred← citeshttps://doi.org/10.1016/j.arr.2020.101153openalex-snapshot
Transposable elements in brain health and disease
inferred← citeshttps://doi.org/10.1016/j.arr.2023.101881openalex-snapshot
Transposable elements and their role in aging
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2014.07.007openalex-snapshot
Retrotransposons in pluripotent cells: Impact and new roles in cellular plasticity
inferred← citeshttps://doi.org/10.1016/j.bbcan.2012.09.001openalex-snapshot
Transposable elements and human cancer: A causal relationship?
inferred← citeshttps://doi.org/10.1016/j.bbcan.2024.189096openalex-snapshot
Understanding the role of DNA methylation in colorectal cancer: Mechanisms, detection, and clinical significance
inferred← citeshttps://doi.org/10.1016/j.bbcan.2024.189143openalex-snapshot
Targeting transposable elements in cancer: developments and opportunities
inferred← citeshttps://doi.org/10.1016/j.bbrc.2015.01.007openalex-snapshot
MILI, a PIWI family protein, inhibits melanoma cell migration through methylation of LINE1
inferred← citeshttps://doi.org/10.1016/j.bpj.2025.03.038openalex-snapshot
Chromatin unfolding via loops can drive clustered transposon insertion
inferred← citeshttps://doi.org/10.1016/j.cancergen.2019.09.002openalex-snapshot
Dysregulated expression of repetitive DNA in ER+/HER2- breast cancer
inferred← citeshttps://doi.org/10.1016/j.cancergen.2020.01.050openalex-snapshot
LINE-1 retrotransposon encoded ORF1p expression and promoter methylation in oral squamous cell carcinoma: a pilot study
inferred← citeshttps://doi.org/10.1016/j.canlet.2012.11.004openalex-snapshot
Genomic sequencing in cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2013.04.008openalex-snapshot
Novel dimensions of piRNAs in cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2020.02.029openalex-snapshot
Reverse transcriptase inhibitors promote the remodelling of nuclear architecture and induce autophagy in prostate cancer cells
inferred← citeshttps://doi.org/10.1016/j.canlet.2025.217874openalex-snapshot
Characterizing chromosome instability reveals its association with lipid-associated macrophages and clonal evolution of lymph node metastasis in esophageal squamous cell carcinoma
inferred← citeshttps://doi.org/10.1016/j.cbpc.2020.108718openalex-snapshot
Cyclophosphamide in Drosophila promotes genes and transposable elements differential expression and mitochondrial dysfunction
inferred← citeshttps://doi.org/10.1016/j.cca.2018.11.018openalex-snapshot
Long interspersed nucleotide element-1 (LINE-1) methylation in colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.ccr.2013.10.002openalex-snapshot
Wiping DNA Methylation: Wip1 Regulates Genomic Fluidity on Cancer
inferred← citeshttps://doi.org/10.1016/j.ccr.2014.02.011openalex-snapshot
RNA Identity Crisis: Hepatitis B Walks the LINE
inferred← citeshttps://doi.org/10.1016/j.ceb.2014.09.002openalex-snapshot
Repetitive elements dynamics in cell identity programming, maintenance and disease
inferred← citeshttps://doi.org/10.1016/j.cell.2012.09.035openalex-snapshot
Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain
inferred← citeshttps://doi.org/10.1016/j.cell.2013.02.032openalex-snapshot
Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.1016/j.cell.2013.03.008openalex-snapshot
Interplay between the Cancer Genome and Epigenome
inferred← citeshttps://doi.org/10.1016/j.cell.2013.04.010openalex-snapshot
Diverse Mechanisms of Somatic Structural Variations in Human Cancer Genomes
inferred← citeshttps://doi.org/10.1016/j.cell.2015.03.026openalex-snapshot
Ubiquitous L1 Mosaicism in Hippocampal Neurons
inferred← citeshttps://doi.org/10.1016/j.cell.2026.05.003openalex-snapshot
Transposable element DNA and RNA: Drivers of gene expression, evolution, and disease
inferred← citeshttps://doi.org/10.1016/j.celrep.2014.10.059openalex-snapshot
Cohesin Rad21 Mediates Loss of Heterozygosity and Is Upregulated via Wnt Promoting Transcriptional Dysregulation in Gastrointestinal Tumors
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.05.090openalex-snapshot
L1 Retrotransposon Heterogeneity in Ovarian Tumor Cell Evolution
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.02.048openalex-snapshot
Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.113749openalex-snapshot
Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.116343openalex-snapshot
Landscape of extrachromosomal DNA characteristics in high-grade serous ovarian cancer via long-read sequencing
inferred← citeshttps://doi.org/10.1016/j.cmet.2019.02.014openalex-snapshot
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
inferred← citeshttps://doi.org/10.1016/j.compbiomed.2026.111541openalex-snapshot
Insertional activity of human Alu and L1 retrotransposons is associated with DNA repair pathways and genome instability in cancer
inferred← citeshttps://doi.org/10.1016/j.copbio.2014.03.001openalex-snapshot
From genomes to societies: a holistic view of determinants of human health
inferred← citeshttps://doi.org/10.1016/j.coviro.2013.09.002openalex-snapshot
Alu elements: an intrinsic source of human genome instability
inferred← citeshttps://doi.org/10.1016/j.csbj.2021.10.037openalex-snapshot
Human endogenous retroviruses in development and disease
inferred← citeshttps://doi.org/10.1016/j.ctrv.2013.05.009openalex-snapshot
The promise and failures of epigenetic therapies for cancer treatment
inferred← citeshttps://doi.org/10.1016/j.cub.2013.10.028openalex-snapshot
Neanderthal and Denisovan retroviruses in modern humans
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2019.10.001openalex-snapshot
Retrotransposons shuttling genetic and epigenetic information from the nuclear to the mitochondrial compartment: Do they play a pathogenetic role in scleroderma?
inferred← citeshttps://doi.org/10.1016/j.envres.2016.06.043openalex-snapshot
Densely ionizing radiation affects DNA methylation of selective LINE-1 elements
inferred← citeshttps://doi.org/10.1016/j.exphem.2016.06.251openalex-snapshot
Transposable elements: The enemies within
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2016.12.027openalex-snapshot
Retrotransposon expression and incorporation of cloned human and mouse retroelements in human spermatozoa
inferred← citeshttps://doi.org/10.1016/j.gde.2013.02.007openalex-snapshot
Functional impact of the human mobilome
inferred← citeshttps://doi.org/10.1016/j.gde.2016.02.005openalex-snapshot
Intracellular mitochondrial DNA transfers to the nucleus in human cancer cells
inferred← citeshttps://doi.org/10.1016/j.gene.2021.145975openalex-snapshot
Transposons: Unexpected players in cancer
inferred← citeshttps://doi.org/10.1016/j.gene.2022.146344openalex-snapshot
Repeat expression is linked to patient survival and exhibits single nucleotide variation in pancreatic cancer revealing LTR70:r.879A>G
inferred← citeshttps://doi.org/10.1016/j.genrep.2025.102364openalex-snapshot
MeX_Docker: An integrated application for transposon identification and annotation based on the Docker platform
inferred← citeshttps://doi.org/10.1016/j.humpath.2019.06.001openalex-snapshot
Expression of L1 retrotransposon open reading frame protein 1 in gynecologic cancers
inferred← citeshttps://doi.org/10.1016/j.isci.2023.108482openalex-snapshot
Comprehensive identification of onco-exaptation events in bladder cancer cell lines revealed L1PA2-SYT1 as a prognosis-relevant event
inferred← citeshttps://doi.org/10.1016/j.isci.2023.108494openalex-snapshot
Characteristics and expression of lncRNA and transposable elements in Drosophila aneuploidy
inferred← citeshttps://doi.org/10.1016/j.jhep.2013.05.001openalex-snapshot
Retrotransposons: A new and credible source of inherited and somatically acquired hepatocellular carcinoma mutations
inferred← citeshttps://doi.org/10.1016/j.molcel.2014.03.032openalex-snapshot
Quiescence-Induced LncRNAs Trigger H4K20 Trimethylation and Transcriptional Silencing
inferred← citeshttps://doi.org/10.1016/j.molcel.2016.10.021openalex-snapshot
An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences
inferred← citeshttps://doi.org/10.1016/j.molcel.2016.11.035openalex-snapshot
pRB Takes an EZ Path to a Repetitive Task
inferred← citeshttps://doi.org/10.1016/j.molcel.2019.05.024openalex-snapshot
LINE-1 Evasion of Epigenetic Repression in Humans
inferred← citeshttps://doi.org/10.1016/j.molonc.2013.04.003openalex-snapshot
Reprogramming of the HepG2 genome by long interspersed nuclear element‐1
inferred← citeshttps://doi.org/10.1016/j.mrrev.2015.05.003openalex-snapshot
Response of transposable elements to environmental stressors
inferred← citeshttps://doi.org/10.1016/j.mrrev.2018.09.003openalex-snapshot
Line-1: Implications in the etiology of cancer, clinical applications, and pharmacologic targets
inferred← citeshttps://doi.org/10.1016/j.neo.2019.11.002openalex-snapshot
Long interspersed element-1 ribonucleoprotein particles protect telomeric ends in alternative lengthening of telomeres dependent cells
inferred← citeshttps://doi.org/10.1016/j.neuron.2014.12.028openalex-snapshot
Cell Lineage Analysis in Human Brain Using Endogenous Retroelements
inferred← citeshttps://doi.org/10.1016/j.neuron.2016.02.004openalex-snapshot
The Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning
inferred← citeshttps://doi.org/10.1016/j.neurot.2025.e00754openalex-snapshot
LINE-1 hypomethylation in cell-free DNA of high-grade glioma patients correlates with tissue levels and is associated with reduced DNMT1 and H4K20me3 expression
inferred← citeshttps://doi.org/10.1016/j.omtn.2020.01.035openalex-snapshot
Targeting Circulating SINEs and LINEs with DNase I Provides Metastases Inhibition in Experimental Tumor Models
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2019.03.004openalex-snapshot
Cancer mutational burden is shaped by G4 DNA, replication stress and mitochondrial dysfunction
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2016.03.004openalex-snapshot
Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2022.108334openalex-snapshot
DNA methylation in cell plasticity and malignant transformation in liver diseases
inferred← citeshttps://doi.org/10.1016/j.semcancer.2018.10.001openalex-snapshot
Human endogenous retroviruses role in cancer cell stemness
inferred← citeshttps://doi.org/10.1016/j.semcancer.2020.12.011openalex-snapshot
Use of DNA methylation profiling in translational oncology
inferred← citeshttps://doi.org/10.1016/j.semcancer.2020.12.014openalex-snapshot
Causes, effects, and clinical implications of perturbed patterns within the cancer epigenome
inferred← citeshttps://doi.org/10.1016/j.semcancer.2021.06.007openalex-snapshot
Giant cells: Linking McClintock’s heredity to early embryogenesis and tumor origin throughout millennia of evolution on Earth
inferred← citeshttps://doi.org/10.1016/j.smim.2017.05.003openalex-snapshot
Interplay between viruses and bacterial microbiota in cancer development
inferred← citeshttps://doi.org/10.1016/j.stem.2015.07.022openalex-snapshot
The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation
inferred← citeshttps://doi.org/10.1016/j.tcb.2025.12.004openalex-snapshot
The role of retrotransposons in hematopoiesis and cancer
inferred← citeshttps://doi.org/10.1016/j.tig.2012.12.002openalex-snapshot
Mobile element biology: new possibilities with high-throughput sequencing
inferred← citeshttps://doi.org/10.1016/j.tig.2017.07.004openalex-snapshot
L1 Mosaicism in Mammals: Extent, Effects, and Evolution
inferred← citeshttps://doi.org/10.1016/j.tig.2018.04.003openalex-snapshot
Detecting Somatic Mutations in Normal Cells
inferred← citeshttps://doi.org/10.1016/j.tig.2025.07.012openalex-snapshot
Single-cell omics sequencing technologies: the long-read generation
inferred← citeshttps://doi.org/10.1016/j.toxlet.2014.05.025openalex-snapshot
Exposure of hepatocellular carcinoma cells to low-level As2O3 causes an extra toxicity pathway via L1 retrotransposition induction
inferred← citeshttps://doi.org/10.1016/j.tranon.2026.102849openalex-snapshot
Variation in LINE-1 ORF1p expression across histologic and demographic subgroups in non-small cell lung cancers
inferred← citeshttps://doi.org/10.1016/j.trecan.2016.08.004openalex-snapshot
Extraordinary Cancer Epigenomics: Thinking Outside the Classical Coding and Promoter Box
inferred← citeshttps://doi.org/10.1016/j.trsl.2012.12.005openalex-snapshot
Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy
inferred← citeshttps://doi.org/10.1016/j.xgen.2023.100484openalex-snapshot
Haplotype-specific assembly of shattered chromosomes in esophageal adenocarcinomas
inferred← citeshttps://doi.org/10.1016/j.ydbio.2020.06.001openalex-snapshot
DNA methylation and the core pluripotency network
inferred← citeshttps://doi.org/10.1016/j.yexcr.2021.112678openalex-snapshot
The role of non-apoptotic cell death in the treatment and drug-resistance of digestive tumors
inferred← citeshttps://doi.org/10.1016/j.ygeno.2019.02.009openalex-snapshot
Chromosomal breakpoints in a cohort of head and neck squamous cell carcinoma patients
inferred← citeshttps://doi.org/10.1017/s2040174421000313openalex-snapshot
DNA methylation profile of liver of mice conceived by in vitro fertilization
inferred← citeshttps://doi.org/10.1038/cr.2018.8openalex-snapshot
Whole-genome sequencing reveals principles of brain retrotransposition in neurodevelopmental disorders
inferred← citeshttps://doi.org/10.1038/emboj.2013.118openalex-snapshot
The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells
inferred← citeshttps://doi.org/10.1038/gim.2015.119openalex-snapshot
LINE-1 in cancer: multifaceted functions and potential clinical implications
inferred← citeshttps://doi.org/10.1038/hgv.2015.30openalex-snapshot
Identification of novel exonic mobile element insertions in epithelial ovarian cancers
inferred← citeshttps://doi.org/10.1038/nature12987openalex-snapshot
PIWI proteins and PIWI-interacting RNAs in the soma
inferred← citeshttps://doi.org/10.1038/ncb2879openalex-snapshot
Senescent cells harbour features of the cancer epigenome
inferred← citeshttps://doi.org/10.1038/ncomms10286openalex-snapshot
Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells
inferred← citeshttps://doi.org/10.1038/ncomms4644openalex-snapshot
Processed pseudogenes acquired somatically during cancer development
inferred← citeshttps://doi.org/10.1038/ncomms6011openalex-snapshot
SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age
inferred← citeshttps://doi.org/10.1038/ncomms8256openalex-snapshot
Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms
inferred← citeshttps://doi.org/10.1038/ng.2702openalex-snapshot
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers
inferred← citeshttps://doi.org/10.1038/nm.3919openalex-snapshot
Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma
inferred← citeshttps://doi.org/10.1038/nrc.2017.35openalex-snapshot
Transposable elements in cancer
inferred← citeshttps://doi.org/10.1038/nrg.2016.139openalex-snapshot
Regulatory activities of transposable elements: from conflicts to benefits
inferred← citeshttps://doi.org/10.1038/nrg3445openalex-snapshot
Cancer genome-sequencing study design
inferred← citeshttps://doi.org/10.1038/nri.2016.27openalex-snapshot
Immune responses to endogenous retroelements: taking the bad with the good
inferred← citeshttps://doi.org/10.1038/nrmicro.2015.22openalex-snapshot
Viral fossils
inferred← citeshttps://doi.org/10.1038/nsmb.2658openalex-snapshot
The Microprocessor controls the activity of mammalian retrotransposons
inferred← citeshttps://doi.org/10.1038/nsmb.3090openalex-snapshot
miR-128 represses L1 retrotransposition by binding directly to L1 RNA
inferred← citeshttps://doi.org/10.1038/onc.2012.516openalex-snapshot
Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor
inferred← citeshttps://doi.org/10.1038/onc.2014.375openalex-snapshot
Wip1 phosphatase in breast cancer
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