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The Accuracy of Reverse Transcriptase from HIV-1
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/0014-5793(86)80303-9openalex-snapshot
Biochemical heterogeneity of reverse transcriptase purified from the AIDS virus, HTLV‐III
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Genetic variation in AIDS viruses
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On the fidelity of DNA replication. Lack of exodeoxyribonuclease activity and error-correcting function in avian myeloblastosis virus DNA polymerase.
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The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation.
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Mutagenesis by transient misalignment.
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Exonucleolytic proofreading enhances the fidelity of DNA synthesis by chick embryo DNA polymerase-gamma.
inferredcites →https://doi.org/10.1016/s0021-9258(18)89090-1openalex-snapshot
The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations.
inferredcites →https://doi.org/10.1016/s0021-9258(19)37638-0openalex-snapshot
Studies on the mechanism of human immunodeficiency virus reverse transcriptase. Steady-state kinetics, processivity, and polynucleotide inhibition.
inferredcites →https://doi.org/10.1016/s0092-8674(88)90189-4openalex-snapshot
Exonucleolytic proofreading
inferredcites →https://doi.org/10.1021/bi00416a027openalex-snapshot
Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase
inferredcites →https://doi.org/10.1073/pnas.84.14.4865openalex-snapshot
Exonucleolytic proofreading by calf thymus DNA polymerase delta.
inferredcites →https://doi.org/10.1073/pnas.85.19.7064openalex-snapshot
Fidelity of a human cell DNA replication complex.
inferredcites →https://doi.org/10.1093/genetics/109.4.633openalex-snapshot
MECHANISMS OF SPONTANEOUS AND INDUCED FRAMESHIFT MUTATION IN BACTERIOPHAGE T4
inferredcites →https://doi.org/10.1101/sqb.1966.031.01.014openalex-snapshot
Frameshift Mutations and the Genetic Code
inferredcites →https://doi.org/10.1126/science.3012778openalex-snapshot
Genetic Variation in HTLV-III/LAV Over Time in Patients with AIDS or at Risk for AIDS
inferredcites →https://doi.org/10.1126/science.3277274openalex-snapshot
The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis
inferredcites →https://doi.org/10.1128/mcb.9.2.469openalex-snapshot
Fidelity of Two Retroviral Reverse Transcriptases during DNA-Dependent DNA Synthesis In Vitro
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Use of Single-Cycle Analysis to Study Rates and Mechanisms of Retroviral Mutation
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Retroviral Recombination Is Nonrandom and Sequence Dependent
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Molecular and Biological Interactions between Two HIV-1 Strains from a Coinfected Patient Reveal the First Evidence in Favor of Viral Synergism
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In Vitro Strand Transfer from Broken RNAs Results in Mismatch but Not Frameshift Mutations
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The Epidemiology of HIV and AIDS
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Human Immunodeficiency Virus Replication in the Presence of Antiretroviral Drugs: Analogies to Antineoplastic Drug Resistance
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Retroelements: Propagation and Adaptation
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Role of the Nucleolus in HIV Infection and Therapy
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HIV Treatment Scale-up in Africa: The Impact of Drug Resistance
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Human Immunodeficiency Virus Reverse Transcriptase
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HIV Reverse Transcriptase Fidelity, Clade Diversity, and Acquisition of Drug Resistance
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Evolutionary Potential of Complex Retroviruses
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Mechanisms of Retrovirus Replication
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Complications of RNA Heterogeneity for the Engineering of Virus Vaccines and Antiviral Agents
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Mechanistic Analysis of HIV-1 Reverse Transcriptase
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Genetic Variation in Retroviruses
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Immune Response to Retroviral Infection
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Principles of HIV Gene Therapy
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Analysis of Mitochondrial DNA and RNA Integrity by a Real-Time qPCR-Based Method
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Mutational Immune Escape in HIV-1 Infection
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Sequence Accuracy in Primary Databases: A Case Study on HIV-1B
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Intrahost Selective Pressure and HIV-1 Heterogeneity During Progression to AIDS
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HIV-Specific Neutralizing Antibodies
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Resistance to Nucleoside and Nucleotide Reverse Transcriptase Inhibitors
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Biological Basis and Clinical Significance of HIV Resistance to Antiviral Drugs
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Basics of Molecular Biology
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Resistance Mechanisms to HIV-1 Nucleoside Reverse Transcriptase Inhibitors
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Antigenic Variation and Immune Escape in the MTBC
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Construction of Rough Set-Based Classifiers for Predicting HIV Resistance to Nucleoside Reverse Transcriptase Inhibitors
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Genetic Diversity and Evolution of Retroviruses
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Retroviral Reverse Transcriptases: Error Frequencies and Mutagenesis
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Human Immunodeficiency Virus Type 1 Quasispecies In Vivo and Ex Vivo
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Envelope Sequence Variation, Neutralizing Antibodies, and Primate Lentivirus Persistence
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Vergleich der biologischen Resistenzbestimmung von HIV-Stämmen gegenüber Azidothymidin (AZT) mit der Sequenzanalyse des Polymerasegens
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Prime Boost Regimens for Enhancing Immunity: Magnitude, Quality of Mucosal and Systemic Gene Vaccines
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Natural History of HIV Infection
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Large DNA Template Dependent Error Variation During Transcription
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Evolution of mutation rate and virulence among human retroviruses
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The role of HIV variability in the pathogenesis of AIDS
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Biological Variability of HIV-1
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BARE-1, a copia-like retroelement in barley (Hordeum vulgare L.)
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On the early emergence of reverse transcription: Theoretical basis and experimental evidence
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Nucleotide composition as a driving force in the evolution of retroviruses
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Mutants from V79 fibroblasts exhibiting hypersensitivity to aphidicolin and 3?-azido-3?-deoxythymidine
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Generation of multiple drug resistance by sequential in vitro passage of the human immunodeficiency virus type 1
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Retroelements: Propagation and adaptation
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Competitive inhibitors of human immunodeficiency virus reverse transcriptase
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Four Classes of HERV-K Long Terminal Repeats and Their Relative Promoter Strengths for Transcription
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The Effect of Increased Processivity on Overall Fidelity of Human Immunodeficiency Virus Type 1 Reverse Transcriptase
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Gene therapy of T helper cells in HIV infection: Mathematical model of the criteria for clinical effect
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A recombination-based strategy for assembling open-reading frames
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Current Status of the Development of HIV Protease Inhibitors and Their Clinical Potential
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Nucleoside and nucleotide inhibitors of HIV-1 replication
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Mechanisms of viral mutation
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The influence of antigenic variation on cytotoxic T lymphocyte responses in HIV-1 infection
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HIV-1 reverse transcriptase inhibitors
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Genetic diversity of Brazilian isolates of feline immunodeficiency virus
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HIV-1 sequences isolated from patients promote expression of shorter isoforms of the Gag polyprotein
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Feline immudeficiency virus subtypes B and A in cats from São Luis, Maranhão, Brazil
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Genomic heterogeneity of small ruminant lentiviruses: existenceof heterogeneous populations in sheep and of the samelentiviral genotypes in sheep and goats
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Mutations in the SIV env and the M13 lacZa gene generatedin vitro by reverse transcriptases and DNA polymerases
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The mechanism of retroviral recombination: the role ofsequences proximal to the point of strand transfer
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Human immunodeficiency virus reverse transcriptase base misincorporations can promote strand transfer
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Inhibition of Viruses by RNA Interference
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The potential emerging role of piRNA/PIWI complex in virus infection
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Targeting host cofactors to inhibit viral infection
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Modeling Within-Host Evolution of HIV: Mutation, Competition and Strain Replacement
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Impact of Latently Infected Cells on Strain Archiving Within HIV Hosts
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Resistance to DAAs: When to Look and When It Matters
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Indinavir resistance evolution in one human immunodeficiency virus type 1 infected patient revealed by single-genome amplification
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Discordant genotypic resistance and HIV-1 genetic diversity from paired plasma and cerebrospinal fluid samples in Chinese settings
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Human cell lines stably expressing HIV env and tat gene products
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Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate
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On the origins of genetic variants
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A possible role for cysteine residues in the fidelity of DNA synthesis exhibited by the reverse transcriptases of human immunodeficiency viruses type 1 and type 2
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Fidelity of the reverse transcriptase of human immunodeficiency virus type 2
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The fidelity of the reverse transcriptases of human immunodeficiency viruses and murine leukemia virus, exhibited by the mispair extension frequencies, is sequence dependent and enzyme related
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Mutational studies of human immunodeficiency virus type 1 reverse transcriptase : the involvement of residues 183 and 184 in the fidelity of DNA synthesis
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A novel protein immunoassay with predetermined specificity using monoclonal antibodies against tryptic fragments: application to HIV P24 antigen
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Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural RNA
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Site-directed mutagenesis for quantitation of base-base interactions at defined sites
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AZT (zidovudine) may act postintegrationally to inhibit generation of HIV-1 progeny virus in chronically infected cells
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Nucleotide sequence and genome organization of biologically active proviruses of the bovine immunodeficiency-like virus
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Envelope gene sequence of HTLV-1 isolate MT-2 and its comparison with other HTLV-1 isolates
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Limited sequence variation in human T-lymphotropic virus type 1 isolates from North American and African patients
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Purification and partial characterization of equine infectious anemia virus reverse transcriptase
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Structure and pathogenicity of individual variants within an immunodeficiency disease-inducing isolate of FeLV
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Subversion of the immune system by pathogens
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Strategy for developing a genetically-engineered whole-virus vaccine against HIV
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Therapeutic applications of ribozymes
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On a coupled map lattice formulation of the evolution of genetic sequences
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AIDS pathogenesis: a dynamic interaction between HIV and the immune system
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Molecular sequence accuracy: analysing imperfect data
inferred← citeshttps://doi.org/10.1016/0190-9622(90)70175-hopenalex-snapshot
Antiviral therapy against HIV infection
inferred← citeshttps://doi.org/10.1016/0378-1135(90)90174-topenalex-snapshot
Methodologies for in vitro nucleic acid amplification and their applications
inferred← citeshttps://doi.org/10.1016/0966-842x(96)81500-9openalex-snapshot
Mechanisms of retroviral mutation
inferred← citeshttps://doi.org/10.1016/b0-08-045044-x/00002-xopenalex-snapshot
Drug Discovery: Historical Perspective, Current Status, and Outlook
inferred← citeshttps://doi.org/10.1016/b978-0-08-091832-7.50007-8openalex-snapshot
Human Immunodeficiency Virus (HIV) Gene Structure and Genetic Diversity
inferred← citeshttps://doi.org/10.1016/b978-0-08-091832-7.50021-2openalex-snapshot
Toward the Rational Design of Antiretroviral Therapy for Human Immunodeficiency Virus (HIV) Infection
inferred← citeshttps://doi.org/10.1016/b978-0-08-097086-8.27002-5openalex-snapshot
AIDS: Acquired Immune-Deficiency Syndrome
inferred← citeshttps://doi.org/10.1016/b978-0-12-374153-0.00008-4openalex-snapshot
The Role of the APOBEC3 Family of Cytidine Deaminases in Innate Immunity, G-to-A Hypermutation, and Evolution of Retroviruses
inferred← citeshttps://doi.org/10.1016/b978-0-12-803309-8.00002-1openalex-snapshot
Genetic Instability of RNA Viruses
inferred← citeshttps://doi.org/10.1016/b978-0-12-804678-4.00007-5openalex-snapshot
cDNA—A Permanent Biochemical Record of the Cell
inferred← citeshttps://doi.org/10.1016/b978-0-323-85679-9.00002-7openalex-snapshot
Genetic instability of RNA viruses
inferred← citeshttps://doi.org/10.1016/b978-0-443-06981-9.50050-8openalex-snapshot
HIV, HTLV, and Other Retroviruses
inferred← citeshttps://doi.org/10.1016/b978-0-8089-2442-5.00012-2openalex-snapshot
10.1016/b978-0-8089-2442-5.00012-2
inferred← citeshttps://doi.org/10.1016/b978-012200741-5/50005-2openalex-snapshot
Biological Properties of HIV-1 and Their Relevance for Aids Pathogenesis
inferred← citeshttps://doi.org/10.1016/b978-012200741-5/50016-7openalex-snapshot
HIV Resistance to Antagonists of Viral Reverse Transcriptase
inferred← citeshttps://doi.org/10.1016/b978-012220360-2/50006-4openalex-snapshot
The Fidelity of Cellular and Viral polymerases and its manipulation for Hypermutagenesis
inferred← citeshttps://doi.org/10.1016/b978-012220360-2/50010-6openalex-snapshot
Dynamics of HIV Pathogenesis and Treatment
inferred← citeshttps://doi.org/10.1016/b978-012437551-2/50007-0openalex-snapshot
The Advent of Lentiviral Vectors: Prospects for Cancer Therapy
inferred← citeshttps://doi.org/10.1016/b978-012492543-4/50031-3openalex-snapshot
The Transcription of Genes
inferred← citeshttps://doi.org/10.1016/b978-012764051-8/50013-5openalex-snapshot
Immunodeficiency in HIV-1 Infection
inferred← citeshttps://doi.org/10.1016/b978-1-4160-2882-6.50018-6openalex-snapshot
Development and Transmission of HIV Drug Resistance
inferred← citeshttps://doi.org/10.1016/b978-1-4557-0695-2.00012-2openalex-snapshot
Development and transmission of HIV drug resistance
inferred← citeshttps://doi.org/10.1016/j.ab.2006.10.009openalex-snapshot
Escherichia coli DNA polymerase III ε subunit increases Moloney murine leukemia virus reverse transcriptase fidelity and accuracy of RT–PCR procedures
inferred← citeshttps://doi.org/10.1016/j.antiviral.2005.03.004openalex-snapshot
KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis
inferred← citeshttps://doi.org/10.1016/j.antiviral.2009.09.008openalex-snapshot
Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989–2009)
inferred← citeshttps://doi.org/10.1016/j.antiviral.2009.09.014openalex-snapshot
Nucleoside and nucleotide HIV reverse transcriptase inhibitors: 25 years after zidovudine
inferred← citeshttps://doi.org/10.1016/j.antiviral.2023.105788openalex-snapshot
Next-generation bNAbs for HIV-1 cure strategies
inferred← citeshttps://doi.org/10.1016/j.bbagen.2014.04.001openalex-snapshot
A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase
inferred← citeshttps://doi.org/10.1016/j.bbrc.2005.10.092openalex-snapshot
Hypophosphoric acid is a unique substrate of pyrophosphorolysis catalyzed by HIV-1 reverse transcriptase
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.07.169openalex-snapshot
Next-generation sequencing-based analysis of reverse transcriptase fidelity
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.151716openalex-snapshot
Engineering thermostable friend mouse leukemia virus reverse transcriptase through mutational combination
inferred← citeshttps://doi.org/10.1016/j.biocel.2004.02.025openalex-snapshot
Nucleoside-analog resistance mutations in HIV-1 reverse transcriptase and their influence on polymerase fidelity and viral mutation rates
inferred← citeshttps://doi.org/10.1016/j.biocel.2004.02.028openalex-snapshot
Primer unblocking by HIV-1 reverse transcriptase and resistance to nucleoside RT inhibitors (NRTIs)
inferred← citeshttps://doi.org/10.1016/j.bmcl.2019.06.047openalex-snapshot
Molecular and cellular studies evaluating a potent 2-cyanoindolizine catechol diether NNRTI targeting wildtype and Y181C mutant HIV-1 reverse transcriptase
inferred← citeshttps://doi.org/10.1016/j.canlet.2020.09.002openalex-snapshot
Extracellular RNA: Emerging roles in cancer cell communication and biomarkers
inferred← citeshttps://doi.org/10.1016/j.cccn.2005.07.009openalex-snapshot
Present and future of rapid and/or high-throughput methods for nucleic acid testing
inferred← citeshttps://doi.org/10.1016/j.chembiol.2004.08.010openalex-snapshot
Combating Susceptibility to Drug Resistance
inferred← citeshttps://doi.org/10.1016/j.coviro.2012.08.004openalex-snapshot
The distinct contributions of fitness and genetic barrier to the development of antiviral drug resistance
inferred← citeshttps://doi.org/10.1016/j.coviro.2018.07.001openalex-snapshot
Adaptation by copy number variation in monopartite viruses
inferred← citeshttps://doi.org/10.1016/j.drup.2011.01.002openalex-snapshot
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase
inferred← citeshttps://doi.org/10.1016/j.ebiom.2021.103678openalex-snapshot
CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.111699openalex-snapshot
Discovery of 2-isoxazol-3-yl-acetamide analogues as heat shock protein 90 (HSP90) inhibitors with significant anti-HIV activity
inferred← citeshttps://doi.org/10.1016/j.ejmech.2023.115188openalex-snapshot
Various strategies for developing APOBEC3G protectors to circumvent human immunodeficiency virus type 1
inferred← citeshttps://doi.org/10.1016/j.ejmech.2023.115449openalex-snapshot
Synthesis and evaluation of DAG-lactone derivatives with HIV-1 latency reversing activity
inferred← citeshttps://doi.org/10.1016/j.enzmictec.2018.05.001openalex-snapshot
Accurate fidelity analysis of the reverse transcriptase by a modified next-generation sequencing
inferred← citeshttps://doi.org/10.1016/j.febslet.2005.01.043openalex-snapshot
The fidelity of DNA synthesis by human immunodeficiency virus type 1 reverse transcriptase increases in the presence of polyamines
inferred← citeshttps://doi.org/10.1016/j.febslet.2006.08.074openalex-snapshot
The incorporation of nucleoside analogs by human immunodeficiency virus type 1 reverse transcriptase decreases in the presence of polyamines
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