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erb B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 Cells
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/j.1460-2075.1985.tb02334.xopenalex-snapshot
The cytoplasmically‐made subunit IV is necessary for assembly of cytochrome c oxidase in yeast.
inferredcites →https://doi.org/10.1002/j.1460-2075.1987.tb04797.xopenalex-snapshot
Overexpression of the EGF receptor‐related proto‐oncogene erbB‐2 in human mammary tumor cell lines by different molecular mechanisms.
inferredcites →https://doi.org/10.1016/0042-6822(73)90341-3openalex-snapshot
A new technique for the assay of infectivity of human adenovirus 5 DNA
inferredcites →https://doi.org/10.1016/0092-8674(82)90065-4openalex-snapshot
Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas
inferredcites →https://doi.org/10.1016/0092-8674(83)90209-xopenalex-snapshot
The erbB gene of avian erythroblastosis virus is a member of the src gene family
inferredcites →https://doi.org/10.1016/0092-8674(86)90779-8openalex-snapshot
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185
inferredcites →https://doi.org/10.1016/s0021-9258(18)43497-7openalex-snapshot
Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.
inferredcites →https://doi.org/10.1016/s0092-8674(85)80047-7openalex-snapshot
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1
inferredcites →https://doi.org/10.1016/s0092-8674(85)80052-0openalex-snapshot
c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor
inferredcites →https://doi.org/10.1016/s0140-6736(80)91256-8openalex-snapshot
HLA ANTIGENS AND SCHIZOPHRENIA
inferredcites →https://doi.org/10.1016/s0140-6736(86)91782-4openalex-snapshot
AMPLIFICATION OF c-erbB-2 ONCOGENE IN HUMAN ADENOCARCINOMAS IN VIVO
inferredcites →https://doi.org/10.1038/290261a0openalex-snapshot
Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts
inferredcites →https://doi.org/10.1038/295419a0openalex-snapshot
Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor
inferredcites →https://doi.org/10.1038/304035a0openalex-snapshot
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus
inferredcites →https://doi.org/10.1038/307521a0openalex-snapshot
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
inferredcites →https://doi.org/10.1038/309418a0openalex-snapshot
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
inferredcites →https://doi.org/10.1038/312513a0openalex-snapshot
The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen
inferredcites →https://doi.org/10.1038/313144a0openalex-snapshot
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
inferredcites →https://doi.org/10.1038/319230a0openalex-snapshot
Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor
inferredcites →https://doi.org/10.1038/320277a0openalex-snapshot
Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus
inferredcites →https://doi.org/10.1073/pnas.78.4.2072openalex-snapshot
Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.
inferredcites →https://doi.org/10.1073/pnas.79.14.4303openalex-snapshot
Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes.
inferredcites →https://doi.org/10.1073/pnas.79.22.6777openalex-snapshot
The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.
inferredcites →https://doi.org/10.1073/pnas.81.1.85openalex-snapshot
Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases.
inferredcites →https://doi.org/10.1073/pnas.81.23.7308openalex-snapshot
Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines.
inferredcites →https://doi.org/10.1073/pnas.82.19.6497openalex-snapshot
A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.
inferredcites →https://doi.org/10.1073/pnas.83.2.261openalex-snapshot
Molecular cloning of the neu gene: absence of gross structural alteration in oncogenic alleles.
inferredcites →https://doi.org/10.1093/nar/13.23.8477openalex-snapshot
Human tumor cell lines with EGF receptor gene amplification in the absence of aberrant sized mRNAs
inferredcites →https://doi.org/10.1126/science.2992089openalex-snapshot
Amplification of a Novel v- erb B-Related Gene in a Human Mammary Carcinoma
inferredcites →https://doi.org/10.1126/science.2992090openalex-snapshot
The neu Gene: an erb B-Homologous Gene Distinct from and Unlinked to the Gene Encoding the EGF Receptor
inferredcites →https://doi.org/10.1126/science.2999974openalex-snapshot
Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene
inferredcites →https://doi.org/10.1126/science.3798106openalex-snapshot
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene
inferredcites →https://doi.org/10.1126/science.6200934openalex-snapshot
Amplification and Enhanced Expression of the Epidermal Growth Factor Receptor Gene in A431 Human Carcinoma Cells
inferredcites →https://doi.org/10.1126/science.6304883openalex-snapshot
Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor
inferredcites →https://doi.org/10.1126/science.6324343openalex-snapshot
Production of an Epidermal Growth Factor Receptor-Related Protein
inferredcites →https://doi.org/10.1128/jvi.60.1.19-28.1986openalex-snapshot
Mammalian cell transformation by a murine retrovirus vector containing the avian erythroblastosis virus erbB gene
inferredcites →https://doi.org/10.1128/mcb.6.3.955openalex-snapshot
Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line.
inferredcites →https://doi.org/10.1128/mcb.6.5.1729openalex-snapshot
p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity.
inferredcites →https://doi.org/10.1146/annurev.bi.54.070185.004341openalex-snapshot
PROTEIN-TYROSINE KINASES
inferredcites →https://doi.org/10.1146/annurev.me.36.020185.002241openalex-snapshot
The Molecular Mechanism of Insulin Action
inferredcites →https://doi.org/10.1146/annurev.ph.47.030185.002041openalex-snapshot
The Nature and Regulation of the Insulin Receptor: Structure and Function
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.5281/zenodo.810572openalex-extracted
Life After Trastuzumab: Neu Strategies For Her2-Positive Breast Cancer
inferred← citesno DOI in the source recordopenalex-snapshot
Staphylococcal nasal carriage of health care workers.
inferred← citeshttps://doi.org/10.1001/archotol.1995.01890110041008openalex-snapshot
HER-2/neu Oncogene Characterization in Head and Neck Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.1002/(sici)1097-0142(19960201)77:3<474::aid-cncr8>3.0.co;2-kopenalex-snapshot
Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients
inferred← citeshttps://doi.org/10.1002/(sici)1097-0215(19970807)72:4<631::aid-ijc14>3.0.co;2-eopenalex-snapshot
Inhibition of tumorigenicity in lung adenocarcinoma cells by c-erbB-2 antisense expression
inferred← citeshttps://doi.org/10.1002/(sici)1097-0215(19990129)80:3<477::aid-ijc23>3.0.co;2-wopenalex-snapshot
New model of ErbB-2 over-expression in human mammary luminal epithelial cells
inferred← citeshttps://doi.org/10.1002/(sici)1097-0215(19990812)82:4<525::aid-ijc10>3.0.co;2-jopenalex-snapshot
Relative cytotoxic activity of immunotoxins reactive with different epitopes on the extracellular domain of the c-erbB-2 (HER-2/neu) gene product p185
inferred← citeshttps://doi.org/10.1002/(sici)1097-0215(19991029)83:3<393::aid-ijc16>3.0.co;2-mopenalex-snapshot
Targeting HER-2/neu for active-specific immunotherapy in a mouse model of spontaneous breast cancer
inferred← citeshttps://doi.org/10.1002/(sici)1097-0347(199805)20:3<224::aid-hed7>3.0.co;2-2openalex-snapshot
Prognostic significance of c-erbB-2 oncoprotein expression in intestinal-type adenocarcinoma of the sinonasal tract
inferred← citeshttps://doi.org/10.1002/(sici)1097-4644(199607)62:1<102::aid-jcb11>3.0.co;2-popenalex-snapshot
NDF induces expression of a novel 46 kD protein in estrogen receptor positive breast cancer cells
inferred← citeshttps://doi.org/10.1002/(sici)1097-4644(19971201)67:3<316::aid-jcb4>3.0.co;2-zopenalex-snapshot
Binding-induced activation of overexpressed p185HER2 is essential in triggering neuronal differentiation of PC12 cells
inferred← citeshttps://doi.org/10.1002/(sici)1097-4644(19990701)74:1<23::aid-jcb3>3.0.co;2-lopenalex-snapshot
Overexpression of ErbB2 impairs ligand-dependent downregulation of epidermal growth factor receptors via a post-transcriptional mechanism
inferred← citeshttps://doi.org/10.1002/(sici)1097-4652(200002)182:2<150::aid-jcp3>3.0.co;2-eopenalex-snapshot
Role of HER2 gene overexpression in breast carcinoma
inferred← citeshttps://doi.org/10.1002/(sici)1098-2264(199812)23:4<307::aid-gcc5>3.0.co;2-#openalex-snapshot
Mapping of chromosomal imbalances in gastric adenocarcinoma revealed amplified protooncogenes MYCN , MET , WNT2 , and ERBB2
inferred← citeshttps://doi.org/10.1002/(sici)1098-2744(199603)15:3<227::aid-mc8>3.0.co;2-eopenalex-snapshot
Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine-phosphorylated p185erbB-2
inferred← citeshttps://doi.org/10.1002/(sici)1098-2744(199707)19:3<165::aid-mc4>3.0.co;2-dopenalex-snapshot
Metastasis induced by overexpression of p185neu-T after orthotopic injection into a prostatic epithelial cell line (NbE)
inferred← citeshttps://doi.org/10.1002/(sici)1098-2744(199810)23:2<62::aid-mc2>3.0.co;2-oopenalex-snapshot
A novel splice variant ofHER2 with increased transformation activity
inferred← citeshttps://doi.org/10.1002/(sici)1520-6823(1996)4:1<1::aid-roi1>3.0.co;2-1openalex-snapshot
Overexpression of a synthetic phosphotyrosine protein phosphatase gene increases radiosensitivity in vitro of normal and transformed murine NIH/3T3 fibroblasts
inferred← citeshttps://doi.org/10.1002/(sici)1521-1878(199801)20:1<41::aid-bies7>3.0.co;2-vopenalex-snapshot
Specificity within the EGF family/ErbB receptor family signaling network
inferred← citeshttps://doi.org/10.1002/1097-0142(19910715)68:2<331::aid-cncr2820680221>3.0.co;2-xopenalex-snapshot
C-ERBB-2 oncogens protein inIn situ and invasive lobular breast neoplasia
inferred← citeshttps://doi.org/10.1002/1097-0142(19930701)72:1<51::aid-cncr2820720112>3.0.co;2-oopenalex-snapshot
An immunohistochemical study of the c-erbB-2 oncogene product in intraductal mucin-hypersecreting neoplasms and in ductal cell carcinomas of the pancreas
inferred← citeshttps://doi.org/10.1002/1097-0142(19940301)73:5<1456::aid-cncr2820730522>3.0.co;2-lopenalex-snapshot
Prevalence and significance of HER-2/neu expression in early epithelial ovarian cancer
inferred← citeshttps://doi.org/10.1002/1097-0215(200002)9999:9999<::aid-ijc1074>3.0.co;2-oopenalex-snapshot
Role of Fas ligand expression in promoting escape from immune rejection in a spontaneous tumor model
inferred← citeshttps://doi.org/10.1002/1097-0215(20000715)87:2<186::aid-ijc5>3.0.co;2-1openalex-snapshot
p185neu protein is required for tumor and anchorage-independent growth, not for cell proliferation of transgenic mammary carcinoma
inferred← citeshttps://doi.org/10.1002/1097-0215(20000815)87:4<553::aid-ijc15>3.0.co;2-8openalex-snapshot
A HER2/NEU-derived peptide, a Kd-restricted murine tumor rejection antigen, induces HER2-specific HLA-A2402-restricted CD8+ cytotoxic T lymphocytes
inferred← citeshttps://doi.org/10.1002/1097-0215(20001015)88:2<267::aid-ijc19>3.0.co;2-gopenalex-snapshot
A novel recombinant fusion toxin targeting HER-2/NEU-over-expressing cells and containing human tumor necrosis factor
inferred← citeshttps://doi.org/10.1002/1097-0215(20001101)88:3<329::aid-ijc2>3.0.co;2-5openalex-snapshot
Salivary carcinoma in HER-2/neu transgenic male mice: An angiogenic switch is not required for tumor onset and progression
inferred← citeshttps://doi.org/10.1002/1097-4652(200010)185:1<1::aid-jcp1>3.0.co;2-oopenalex-snapshot
Retinoids and ovarian cancer
inferred← citeshttps://doi.org/10.1002/9780470454923.ch13openalex-snapshot
Media and Extra Cellular Matrix Requirements for Large‐Scale ESC Growth
inferred← citeshttps://doi.org/10.1002/9780470485408.ch31openalex-snapshot
Therapeutic Antibodies in Clinical Use and Leading Clinical Candidates
inferred← citeshttps://doi.org/10.1002/9781119967309.ch2openalex-snapshot
Cancer Biomarkers for Diagnosis, Prognosis and Therapy
inferred← citeshttps://doi.org/10.1002/ajmg.a.37609openalex-snapshot
Identification of a novel insertion mutation in FGFR3 that causes thanatophoric dysplasia type 1
inferred← citeshttps://doi.org/10.1002/bies.950151207openalex-snapshot
Neu and its ligands: From an oncogene to neural factors
inferred← citeshttps://doi.org/10.1002/cam4.5288openalex-snapshot
Breastfeeding reduces the risk of breast cancer: A call for action in high‐income countries with low rates of breastfeeding
inferred← citeshttps://doi.org/10.1002/cmdc.200600174openalex-snapshot
Advances towards the Development of ATP‐Competitive Small‐Molecule Inhibitors of the Insulin‐Like Growth Factor Receptor (IGF‐IR)
inferred← citeshttps://doi.org/10.1002/cncr.10339openalex-snapshot
HER‐2 profiling and targeting in prostate carcinoma
inferred← citeshttps://doi.org/10.1002/cncr.10839openalex-snapshot
Evaluation of HER‐2/neu expression in prostatic adenocarcinoma
inferred← citeshttps://doi.org/10.1002/cncr.2820710209openalex-snapshot
Growth regulation and transformation of ovarian epithelium
inferred← citeshttps://doi.org/10.1002/cncr.30869openalex-snapshot
HER2 mutations in lung adenocarcinomas: A report from the Lung Cancer Mutation Consortium
inferred← citeshttps://doi.org/10.1002/cncy.22124openalex-snapshot
The past, present, and future of HER2 (ERBB2) in cancer: Approaches to molecular testing and an evolving role in targeted therapy
inferred← citeshttps://doi.org/10.1002/cyto.a.24922openalex-snapshot
EGFR ‐ HER2 Transactivation Viewed in Space and Time Through the Versatile Spectacles of Imaging Cytometry—Implications for Targeted Therapy
inferred← citeshttps://doi.org/10.1002/eji.1830241143openalex-snapshot
Antigenic and immunogenic mimicry of the HER2/neu oncoprotein by phage‐displayed peptides
inferred← citeshttps://doi.org/10.1002/gcc.20624openalex-snapshot
ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry
inferred← citeshttps://doi.org/10.1002/gcc.2870030208openalex-snapshot
Expression of the ERBB2 protein in benign and malignant salivary gland tumors
inferred← citeshttps://doi.org/10.1002/gcc.2870030403openalex-snapshot
Cytogenetics of papillary renal cell tumors
inferred← citeshttps://doi.org/10.1002/humu.20955openalex-snapshot
Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: Molecular diversity and associated phenotypic spectrum
inferred← citeshttps://doi.org/10.1002/ijc.10129openalex-snapshot
No association between HER‐2 gene polymorphism at codon 655 and a risk of bladder cancer
inferred← citeshttps://doi.org/10.1002/ijc.1459openalex-snapshot
Truncated ErbB2 receptor enhances ErbB1 signaling and induces reversible, ERK-independent loss of epithelial morphology
inferred← citeshttps://doi.org/10.1002/ijc.20536openalex-snapshot
Xenogeneic immunization in mice using HER2 DNA delivered by an adenoviral vector
inferred← citeshttps://doi.org/10.1002/ijc.21426openalex-snapshot
Inefficient proteasomal‐degradation pathway stabilizes AP‐2α and activates HER‐2/neu gene in breast cancer
inferred← citeshttps://doi.org/10.1002/ijc.22606openalex-snapshot
Rapamycin together with herceptin significantly increased anti‐tumor efficacy compared to either alone in ErbB2 over expressing breast cancer cells
inferred← citeshttps://doi.org/10.1002/ijc.24995openalex-snapshot
Synergism from combined immunologic and pharmacologic inhibition of HER2 in vivo
inferred← citeshttps://doi.org/10.1002/ijc.2910420524openalex-snapshot
Expression of the c‐Ha‐ras and neu oncogenes in DMBA‐induced, anti‐estrogen‐treated rat mammary tumors
inferred← citeshttps://doi.org/10.1002/ijc.2910420608openalex-snapshot
Immunohistochemical distribution of c‐erbB‐2 in infiltrating and in situ breast cancer
inferred← citeshttps://doi.org/10.1002/ijc.2910450314openalex-snapshot
Expression of the p185 encoded by her2 oncogene in normal and transformed human tissues
inferred← citeshttps://doi.org/10.1002/ijc.2910460708openalex-snapshot
4. The role of the epidermal growth factor receptor and the c-erbB-2 protein in breast cancer
inferred← citeshttps://doi.org/10.1002/ijc.2910490425openalex-snapshot
Estrogen suppression of erbB2 expression is associated with increased growth rate of ZR‐75‐1 human breast cancer cells in vitro and in nude mice
inferred← citeshttps://doi.org/10.1002/ijc.2910530322openalex-snapshot
Cellular and In Vivo characterization of the MCR rat mammary tumor model
inferred← citeshttps://doi.org/10.1002/ijc.2910540209openalex-snapshot
Amplification and over‐expression of the EGFR and erbB‐2 genes in human esophageal adenocarcinomas
inferred← citeshttps://doi.org/10.1002/ijc.2910550122openalex-snapshot
Characterization of cytotoxic activity of saporin anti‐gp185/HER‐2 immunotoxins
inferred← citeshttps://doi.org/10.1002/ijc.2910560308openalex-snapshot
Expression of gp 185HER‐2 in human cutaneous melanoma: Implications for experimental immunotherapeutics
inferred← citeshttps://doi.org/10.1002/ijc.2910580415openalex-snapshot
Interferon gamma‐induced reduction in erbB‐2 tyrosyl phosphorylation in human ovarian carcinoma cells
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1988.tb02906.xopenalex-snapshot
EGF‐stimulated tyrosine phosphorylation of p185neu: a potential model for receptor interactions.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1988.tb02907.xopenalex-snapshot
Primary structure of c‐kit: relationship with the CSF‐1/PDGF receptor kinase family–oncogenic activation of v‐kit involves deletion of extracellular domain and C terminus.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1988.tb02991.xopenalex-snapshot
Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB‐2 protein in the mammary tumor cell line SK‐BR‐3.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1988.tb03044.xopenalex-snapshot
Oncogenic activation of the neu‐encoded receptor protein by point mutation and deletion.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1988.tb03093.xopenalex-snapshot
Molecular cloning and characterization of the human dbl proto‐oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1989.tb03360.xopenalex-snapshot
A chimeric EGF‐R‐neu proto‐oncogene allows EGF to regulate neu tyrosine kinase and cell transformation.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1989.tb03361.xopenalex-snapshot
HER2 cytoplasmic domain generates normal mitogenic and transforming signals in a chimeric receptor.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1989.tb03605.xopenalex-snapshot
Molecular characterization of a gene of the ‘EGF family’ expressed in undifferentiated human NTERA2 teratocarcinoma cells.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1990.tb08094.xopenalex-snapshot
Induction of a variety of tumors by c‐erbB2 and clonal nature of lymphomas even with the mutated gene (Val659‐‐‐‐Glu659).
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1991.tb04935.xopenalex-snapshot
Ligand stimulation of transfected and endogenous growth factor receptors enhances cytokine production by mast cells.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1991.tb07739.xopenalex-snapshot
Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1992.tb05131.xopenalex-snapshot
A subdomain in the transmembrane domain is necessary for p185neu* activation.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1992.tb05486.xopenalex-snapshot
A single amino acid substitution is sufficient to modify the mitogenic properties of the epidermal growth factor receptor to resemble that of gp185erbB‐2.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1993.tb05737.xopenalex-snapshot
Cell‐type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER‐2 suggests complex ligand‐receptor relationships.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1994.tb06577.xopenalex-snapshot
Identification of c‐erbB‐3 binding sites for phosphatidylinositol 3′‐kinase and SHC using an EGF receptor/c‐erbB‐3 chimera.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1995.tb00101.xopenalex-snapshot
Heregulin‐dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1996.tb00356.xopenalex-snapshot
ErbB‐2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer.
inferred← citeshttps://doi.org/10.1002/j.1460-2075.1996.tb00632.xopenalex-snapshot
Molecular heterogeneity of RET loss of function in Hirschsprung's disease.
inferred← citeshttps://doi.org/10.1002/jcb.22754openalex-snapshot
Early response to ErbB2 over‐expression in polarized Caco‐2 cells involves partial segregation from ErbB3 by relocalization to the apical surface and initiation of survival signaling
inferred← citeshttps://doi.org/10.1002/jcb.240390207openalex-snapshot
Retroviruses expressing different levels of the normal epidermal growth factor receptor: Biological properties and new bioassay
inferred← citeshttps://doi.org/10.1002/jcb.240390208openalex-snapshot
Overexpression of the c‐erbB‐2 protein in human breast tumor cell lines
inferred← citeshttps://doi.org/10.1002/jcb.240530108openalex-snapshot
Interaction of the neu/p185 and EGF receptor tyrosine kinases: Implications for cellular transformation and tumor therapy
inferred← citeshttps://doi.org/10.1002/jcb.240590931openalex-snapshot
Screening for ovarian cancer: What are the optimal surrogate endpoints for clinical trials?
inferred← citeshttps://doi.org/10.1002/jcb.24111openalex-snapshot
Ultrasensitive detection of cellular protein interactions using bioluminescence resonance energy transfer quantum dot‐based nanoprobes
inferred← citeshttps://doi.org/10.1002/jcp.22257openalex-snapshot
Shed HER2 extracellular domain in HER2‐mediated tumor growth and in trastuzumab susceptibility
inferred← citeshttps://doi.org/10.1002/jcp.22333openalex-snapshot
Lapatinib, a dual HER1/HER2 tyrosine kinase inhibitor, augments basal cleavage of HER2 extracellular domain (ECD) to inhibit HER2‐driven cancer cell growth
inferred← citeshttps://doi.org/10.1002/jemt.10181openalex-snapshot
Prognostic and predictive value of HER2/neu oncogene in breast cancer
inferred← citeshttps://doi.org/10.1002/mc.20054openalex-snapshot
Pharmacological inhibition of fatty acid synthase (FAS): A novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her‐2/neu (erbB‐2) oncogene‐induced malignant transformation
inferred← citeshttps://doi.org/10.1002/mc.2940030406openalex-snapshot
Direct sequencing analysis of transmembrane region of human neu gene by polymerase chain reaction
inferred← citeshttps://doi.org/10.1002/mc.2940030503openalex-snapshot
Amplification and expression of the c‐erb B‐2/neu proto‐oncogene in human bladder cancer
inferred← citeshttps://doi.org/10.1002/mc.2940030607openalex-snapshot
Differentiation of cultured human breast cancer cells (AU‐565 and MCF‐7) associated with loss of cell surface HER‐2/neu antigen
inferred← citeshttps://doi.org/10.1002/mc.2940090407openalex-snapshot
Infrequent transforming mutations in the transmembrane domain of the neu oncogene in spontaneous rat schwannomas
inferred← citeshttps://doi.org/10.1002/path.1240openalex-snapshot
The role of heregulin‐α as a motility factor and amphiregulin as a growth factor in wound healing
inferred← citeshttps://doi.org/10.1002/path.1711590204openalex-snapshot
c‐erbB‐2 oncogene product staining in gastric adenocarcinoma. An immunohistochemical study
inferred← citeshttps://doi.org/10.1002/path.1711640403openalex-snapshot
Immunohistochemical detection of the epidermal growth factor receptor in paraffin‐embedded human tissues
inferred← citeshttps://doi.org/10.1002/path.4502openalex-snapshot
Erbin interacts with c‐Cbl and promotes tumourigenesis and tumour growth in colorectal cancer by preventing c‐Cbl‐mediated ubiquitination and down‐regulation of EGFR
inferred← citeshttps://doi.org/10.1002/prca.201200075openalex-snapshot
Breast cancer biomarker measurements and standards
inferred← citeshttps://doi.org/10.1002/slct.202303604openalex-snapshot
Design, Synthesis, Biological Evaluation, and Molecular Docking Studies of 4‐Nitrobenzohydrazide Derivatives as Potential Anticancer Agents
inferred← citeshttps://doi.org/10.1002/stem.150001openalex-snapshot
HER‐2/ neu Signal Transduction in Human Breast and Ovarian Cancer
inferred← citeshttps://doi.org/10.1006/bbrc.1999.0634openalex-snapshot
Identification of a Novel Promoter and Exons of the c-ERBB-2Gene
inferred← citeshttps://doi.org/10.1006/bbrc.1999.1144openalex-snapshot
Heregulin Regulation of Akt/Protein Kinase B in Breast Cancer Cells
inferred← citeshttps://doi.org/10.1006/excr.1996.3468openalex-snapshot
Expression of the Activated p185erbB2Tyrosine Kinase in Human Epithelial Cells Leads to MAP Kinase Activation but Does Not Confer Oncogenicity
inferred← citeshttps://doi.org/10.1006/excr.1997.3695openalex-snapshot
α6β4 and α6β1 Integrins Associate with ErbB-2 in Human Carcinoma Cell Lines
inferred← citeshttps://doi.org/10.1006/exmp.1999.2266openalex-snapshot
Shared Antigenic Epitopes and Pathobiological Functions of Anti-p185 Monoclonal Antibodies
inferred← citeshttps://doi.org/10.1006/gyno.1997.4661openalex-snapshot
p53 and HER-2/neu Overexpression in Ovarian Borderline Tumors
inferred← citeshttps://doi.org/10.1006/gyno.1999.5467openalex-snapshot
An Alternative HER-2/neu Transcript of 8 kb Has an Extended 3′UTR and Displays Increased Stability in SKOV-3 Ovarian Carcinoma Cells
inferred← citeshttps://doi.org/10.1006/jmbi.1998.1948openalex-snapshot
A bivalent disulfide-stabilized fv with improved antigen binding to erbb2
inferred← citeshttps://doi.org/10.1006/jmbi.2001.5111openalex-snapshot
Targeted gene transduction of mammalian cells expressing the HER2/neu receptor by filamentous phage 1 1Edited by J. Karn
inferred← citeshttps://doi.org/10.1007/2-287-31109-2_11openalex-snapshot
Breast cancer with HER 2 overexpressed. From laboratory to clinical practice
inferred← citeshttps://doi.org/10.1007/3-540-26337-3_14openalex-snapshot
Cervical and Endometrial Cancer Prevention
inferred← citeshttps://doi.org/10.1007/3-7643-7414-4_3openalex-snapshot
Tumor models for preclinical development of targeted agents
inferred← citeshttps://doi.org/10.1007/978-0-387-69080-3_29openalex-snapshot
Her-2/neu-induced “Cytokine Signature” in Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-1-349-10671-4_12openalex-snapshot
The Structure and Function of Growth Factor Receptors and Their Subversion in Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4020-8341-9_4openalex-snapshot
The Impact of ErbB2 on Cancer Progression and Metastasis through Modulation of Tumor and Tumor Microenvironment
inferred← citeshttps://doi.org/10.1007/978-1-4419-0507-9_13openalex-snapshot
The Biology of the HER Family and Her2/neu Directed-Antibody Therapy
inferred← citeshttps://doi.org/10.1007/978-1-4419-8877-5_6openalex-snapshot
Monoclonal and Bispecific Antibodies in Combination with Radiotherapy for Cancer Treatment
inferred← citeshttps://doi.org/10.1007/978-1-4471-0801-6_28openalex-snapshot
Pancreatic Cancer: Growth Factors and Growth Factor Receptors
inferred← citeshttps://doi.org/10.1007/978-1-4612-1810-4_3openalex-snapshot
Growth Factors and Growth Factor Receptors in Chronic Pancreatitis, and the Relation to Pancreatic Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4612-3162-2_10openalex-snapshot
Growth Factors as Local Regulators of Normal and Malignant Human Mammary Epithelium
inferred← citeshttps://doi.org/10.1007/978-1-4612-4092-1_15openalex-snapshot
Antiestrogen Regulation of erbB2 Expression in Human Breast Cancer Cells
inferred← citeshttps://doi.org/10.1007/978-1-4612-4266-6_7openalex-snapshot
Genetics of Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4613-1151-5_3openalex-snapshot
Nutritional, Hormonal, and Environmental Mechanisms in Breast Tumorigenesis
inferred← citeshttps://doi.org/10.1007/978-1-4613-1733-3_3openalex-snapshot
Different mechanisms are responsible for oncogene activation in human mammary neoplasia
inferred← citeshttps://doi.org/10.1007/978-1-4615-1973-7_6openalex-snapshot
The Role of erbB-Family Genes and Wnt Genes in Normal and Preneoplastic Mammary Epithelium, Studied by Tissue Reconstitution
inferred← citeshttps://doi.org/10.1007/978-1-4615-2592-9_9openalex-snapshot
Molecular and clinical aspects of the Neu/ErbB-2 receptor tyrosine kinase
inferred← citeshttps://doi.org/10.1007/978-1-4615-2926-2_10openalex-snapshot
Breast Cancer: Influence of Endocrine Hormones, Growth Factors and Genetic Alterations
inferred← citeshttps://doi.org/10.1007/978-1-4615-3088-6_2openalex-snapshot
Activated oncogenes and putative tumor suppressor genes involved in human breast cancers
inferred← citeshttps://doi.org/10.1007/978-1-4615-3494-5_1openalex-snapshot
The Role of Oncogenes and Onco-Suppressor Genes in Human Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4615-3494-5_3openalex-snapshot
c-erbB-2, a Tyrosine Kinase Growth Factor Receptor and its Role in Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4615-3500-3_10openalex-snapshot
Anti-p185HER2 monoclonal antibodies: Biological properties and potential for immunotherapy
inferred← citeshttps://doi.org/10.1007/978-1-4615-3500-3_7openalex-snapshot
Mechanisms involving an expanding erbB/EGF receptor family of tyrosine kinases in human neoplasia
inferred← citeshttps://doi.org/10.1007/978-1-4615-3500-3_8openalex-snapshot
c-erb B2 amplification and overexpression in human tumors
inferred← citeshttps://doi.org/10.1007/978-1-4615-3500-3_9openalex-snapshot
Clinical significance of erbB2 protein overexpression
inferred← citeshttps://doi.org/10.1007/978-1-4615-3740-3_7openalex-snapshot
Expression and Prognostic Significance of the HER-2/neu Oncogene During the Evolutionary Progression of Human Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4615-3938-4_2openalex-snapshot
Growth factors regulating normal and malignant melanocytes
inferred← citeshttps://doi.org/10.1007/978-1-4615-3940-7_1openalex-snapshot
Oncogenes as clinical prognostic indicators
inferred← citeshttps://doi.org/10.1007/978-1-4684-5751-3_12openalex-snapshot
The Roles of Transforming Growth Factors α and β in Growth Regulation of Normal and Transformed Human Mammary Epithelial Cells
inferred← citeshttps://doi.org/10.1007/978-1-4757-1296-4_10openalex-snapshot
The Oncogenic Potential of Membrane Receptor Proteins Encoded by Members of the Human erbB Proto-Oncogene Family
inferred← citeshttps://doi.org/10.1007/978-1-4899-1813-0_59openalex-snapshot
The Role of Linoleic Acid Metabolism in the Proliferative Response of Cells Overexpressing the erbB-2/HER2 Oncogene
inferred← citeshttps://doi.org/10.1007/978-1-4939-2886-6_9openalex-snapshot
Molecular Pathology of HER Family of Oncogenes in Breast Cancer: HER-2 Evaluation and Role in Targeted Therapy
inferred← citeshttps://doi.org/10.1007/978-1-4939-3649-6_5openalex-snapshot
The Role of TCPTP in Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4939-7219-7_17openalex-snapshot
Analysis of Epithelial–Mesenchymal Transition Induced by Overexpression of Twist
inferred← citeshttps://doi.org/10.1007/978-1-59259-125-1_23openalex-snapshot
Novel Molecular Targets for Cancer Drug Discovery
inferred← citeshttps://doi.org/10.1007/978-1-59259-223-4_9openalex-snapshot
Epidermal Growth Factor-Related Peptides in Endocrine Neoplasias
inferred← citeshttps://doi.org/10.1007/978-1-59259-313-2_4openalex-snapshot
Oncogenic Receptor Tyrosine Kinases
inferred← citeshttps://doi.org/10.1007/978-1-59745-458-2_38openalex-snapshot
Targeting Oncoproteins for Molecular Cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-1-59745-458-2_7openalex-snapshot
An Overview of Cancer Genes
inferred← citeshttps://doi.org/10.1007/978-3-030-43032-0_5openalex-snapshot
HER2-Targeted Therapy in Osteosarcoma
inferred← citeshttps://doi.org/10.1007/978-3-030-94753-8_21-1openalex-snapshot
Pharmacological Insights into Morin: Therapeutic Applications and Future Perspectives
inferred← citeshttps://doi.org/10.1007/978-3-319-04843-7_9openalex-snapshot
HER-2 Involvement in Osteosarcoma
inferred← citeshttps://doi.org/10.1007/978-3-540-68986-7_18openalex-snapshot
Endometrial Cancer Prevention
inferred← citeshttps://doi.org/10.1007/978-3-540-69414-4_9openalex-snapshot
Tiermodelle in der biomedizinischen Forschung
inferred← citeshttps://doi.org/10.1007/978-3-642-60068-5_20openalex-snapshot
Growth Factors and Transcription Factors in Pancreatic Cancer
inferred← citeshttps://doi.org/10.1007/978-3-642-78984-7_3openalex-snapshot
Do We Carry the Cause of Cancer in Our Genes?
inferred← citeshttps://doi.org/10.1007/978-3-642-78984-7_4openalex-snapshot
Activation of Cancer-Causing Genes (Biochemical Discussion)
inferred← citeshttps://doi.org/10.1007/978-3-642-79782-8_4openalex-snapshot
Hyperexpression von Wachstumsfaktoren
inferred← citeshttps://doi.org/10.1007/978-3-642-83638-1_5openalex-snapshot
Serum Tyrosine Kinase Activity and Neoplastic Disease
inferred← citeshttps://doi.org/10.1007/978-3-642-83638-1_7openalex-snapshot
Expression of the c-erbB-2 Proto-Oncogene Protein in Human Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-3-662-07588-3_10openalex-snapshot
Tiermodelle in der biomedizinischen Forschung
inferred← citeshttps://doi.org/10.1007/978-3-662-08822-7_10openalex-snapshot
Tiermodelle in der biomedizinischen Forschung
inferred← citeshttps://doi.org/10.1007/978-4-431-55552-0_19openalex-snapshot
Human Epidermal Growth Factor Receptor (HER) Family Molecular Structure
inferred← citeshttps://doi.org/10.1007/978-90-481-3725-1_2openalex-snapshot
The Role of Oncogene Activation in Tumor Progression
inferred← citeshttps://doi.org/10.1007/978-981-10-7296-3_3openalex-snapshot
Regulation of microRNA Expression by Growth Factors in Tumor Development and Progression
inferred← citeshttps://doi.org/10.1007/bf00049410openalex-snapshot
Growth factors and tyrosine protein kinases in normal and malignant melanocytes
inferred← citeshttps://doi.org/10.1007/bf00171701openalex-snapshot
erbB-2/Her-2 gene amplification and overexpression in parotid gland tumors
inferred← citeshttps://doi.org/10.1007/bf00177474openalex-snapshot
Immunohistochemical evaluation of erbB-2 and p53 protein expression in benign and atypical human meningiomas
inferred← citeshttps://doi.org/10.1007/bf00202070openalex-snapshot
Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors
inferred← citeshttps://doi.org/10.1007/bf00311556openalex-snapshot
Effectiveness of an adriamycin immunoconjugate that recognizes the c-erbB-2 product on breast cancer cell lines
inferred← citeshttps://doi.org/10.1007/bf00665783openalex-snapshot
MCF-7 breast cancer cells overexpressing transfectedc-erbB-2 have anin vitro growth advantage in estrogen-depleted conditions and reduced estrogen-dependence and tamoxifen-sensitivityin vivo
inferred← citeshttps://doi.org/10.1007/bf00666151openalex-snapshot
Modulation of breast cancer progression and differentiation by thegp30/neregulin
inferred← citeshttps://doi.org/10.1007/bf00683195openalex-snapshot
The role of erbB2 signal transduction pathways in human breast cancer
inferred← citeshttps://doi.org/10.1007/bf00918679openalex-snapshot
Monoclonal antibody therapy of human cancer: Taking the HER2 protooncogene to the clinic
inferred← citeshttps://doi.org/10.1007/bf01024899openalex-snapshot
Conformational changes induced by the transforming amino acid substitution in the transmembrane domain of theneu oncogene-encoded p185 protein
inferred← citeshttps://doi.org/10.1007/bf01612634openalex-snapshot
c-erbB2 expression in correlation to other biological parameters of breast cancer
inferred← citeshttps://doi.org/10.1007/bf01612912openalex-snapshot
Application of molecular cytogenetic techniques to the evaluation of renal parenchymal tumors
inferred← citeshttps://doi.org/10.1007/bf01629433openalex-snapshot
Expression ofHer2/neu oncogene product p185 in correlation to clinicopathological and prognostic factors of gastric carcinoma
inferred← citeshttps://doi.org/10.1007/bf01803780openalex-snapshot
Preclinical testing of an anti-erbB-2 recombinant toxin
inferred← citeshttps://doi.org/10.1007/bf01803784openalex-snapshot
The significance ofheregulin in breast cancer tumor progression and drug resistance
inferred← citeshttps://doi.org/10.1007/bf01806508openalex-snapshot
Determination of ErbB2 protein in breast cancer tissues by different methods. Relationships with other biological parameters
inferred← citeshttps://doi.org/10.1007/bf01806677openalex-snapshot
Epidermal growth factor receptor and c-erbB-2 expression in normal breast tissue during the menstrual cycle
inferred← citeshttps://doi.org/10.1007/bf01902842openalex-snapshot
Conformation of the transmembrane domain of the c-erbB-2 oncogene-encoded protein in its monomeric and dimeric states
inferred← citeshttps://doi.org/10.1007/bf02013643openalex-snapshot
ErbB2 activation and signal transduction in normal and malignant mammary cells
inferred← citeshttps://doi.org/10.1007/bf02710297openalex-snapshot
ErbB tyrosine kinase receptor inhibitors in breast cancer treatment
inferred← citeshttps://doi.org/10.1007/bf02943053openalex-snapshot
c-erbB-2 oncoprotein expression in malignant and nonmalignant breast tissue
inferred← citeshttps://doi.org/10.1007/bf02967477openalex-snapshot
Biological and clinical significance of her2 overexpression in Breast Cancer
inferred← citeshttps://doi.org/10.1007/bf02974664openalex-snapshot
Expression of c-erbB-2 and PCNA in cervical adenocarcinoma and its signification
inferred← citeshttps://doi.org/10.1007/pl00003274openalex-snapshot
Herceptin in the treatment of metastatic breast cancer
inferred← citeshttps://doi.org/10.1007/s00018-004-4277-7openalex-snapshot
Oncogenic protein tyrosine kinases
inferred← citeshttps://doi.org/10.1007/s001090050237openalex-snapshot
The level of erbB2 expression predicts sensitivity to the cytotoxic effects of an intracellular anti-erbB2 sFv
inferred← citeshttps://doi.org/10.1007/s00249-008-0293-0openalex-snapshot
Insight into the recognition patterns of the ErbB receptor family transmembrane domains: heterodimerization models through molecular dynamics search
inferred← citeshttps://doi.org/10.1007/s00259-020-05094-1openalex-snapshot
HER2-directed antibodies, affibodies and nanobodies as drug-delivery vehicles in breast cancer with a specific focus on radioimmunotherapy and radioimmunoimaging
inferred← citeshttps://doi.org/10.1007/s002689900616openalex-snapshot
Concomitant Analysis of the Epidermal Growth Factor Receptor Family in Esophageal Cancer: Overexpression of Epidermal Growth Factor Receptor mRNA but Not of c‐erbB‐2 and c‐erbB‐3
inferred← citeshttps://doi.org/10.1007/s002770050404openalex-snapshot
Antisense strategies for the treatment of hematological malignancies and solid tumors
inferred← citeshttps://doi.org/10.1007/s00292-008-1021-3openalex-snapshot
Unterschiedliche koexistierende Genotypen in der Brustkrebszelllinie MDA-MB-468
inferred← citeshttps://doi.org/10.1007/s00384-006-0192-8openalex-snapshot
HER-2/neu overexpression is an independent prognostic factor in colorectal cancer
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