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ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/eji.201545772openalex-snapshot
Caspase‐11 activates a canonical NLRP3 inflammasome by promoting K + efflux
inferredcites →https://doi.org/10.1002/eji.201747404openalex-snapshot
The Gasdermin‐D pore acts as a conduit for IL‐1β secretion in mice
inferredcites →https://doi.org/10.1016/j.cell.2017.03.020openalex-snapshot
ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences
inferredcites →https://doi.org/10.1016/j.immuni.2017.11.013openalex-snapshot
The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
inferredcites →https://doi.org/10.1016/j.tcb.2014.07.008openalex-snapshot
Damage control: cellular mechanisms of plasma membrane repair
inferredcites →https://doi.org/10.1038/nature10558openalex-snapshot
Non-canonical inflammasome activation targets caspase-11
inferredcites →https://doi.org/10.1038/nature13683openalex-snapshot
Inflammatory caspases are innate immune receptors for intracellular LPS
inferredcites →https://doi.org/10.1038/nature13820openalex-snapshot
Inefficient star formation in extremely metal poor galaxies
inferredcites →https://doi.org/10.1038/nature15514openalex-snapshot
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
inferredcites →https://doi.org/10.1038/nature15541openalex-snapshot
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
inferredcites →https://doi.org/10.1038/nature18590openalex-snapshot
Pore-forming activity and structural autoinhibition of the gasdermin family
inferredcites →https://doi.org/10.1038/nature18629openalex-snapshot
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
inferredcites →https://doi.org/10.1038/ncomms6646openalex-snapshot
Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair
inferredcites →https://doi.org/10.1038/nmeth.1199openalex-snapshot
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals
inferredcites →https://doi.org/10.1038/nri.2016.58openalex-snapshot
Inflammasomes: mechanism of assembly, regulation and signalling
inferredcites →https://doi.org/10.1073/pnas.1607769113openalex-snapshot
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
inferredcites →https://doi.org/10.1083/jcb.201003053openalex-snapshot
Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair
inferredcites →https://doi.org/10.1126/science.1247136openalex-snapshot
ESCRT Machinery Is Required for Plasma Membrane Repair
inferredcites →https://doi.org/10.1126/science.aar5078openalex-snapshot
Triggered recruitment of ESCRT machinery promotes endolysosomal repair
inferredcites →https://doi.org/10.15252/embj.201694696openalex-snapshot
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Mots-C Inhibits Pyroptosis by Promoting the Expression Chmp4b
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Advanced Nanoarchitectonics of Drug Delivery Systems with Pyroptosis Inhibition for Noncancerous Disease Treatment
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Nanomaterials for Disease Treatment by Modulating the Pyroptosis Pathway
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Copper‐Bacteriochlorin Nanosheet as a Specific Pyroptosis Inducer for Robust Tumor Immunotherapy
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Programmed Targeting Pyruvate Metabolism Therapy Amplified Single‐Atom Nanozyme‐Activated Pyroptosis for Immunotherapy
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Embryo‐Derived Cathepsin B Promotes Implantation and Decidualization by Activating Pyroptosis
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Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications
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Hepatocyte‐Specific GSDMD Deficiency Aggravates Sepsis by Disrupting Non‐Canonical Secretion of Anti‐Inflammatory Factors
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Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis
inferred← citeshttps://doi.org/10.1002/ange.202309786openalex-snapshot
In Situ Self‐Assembled J‐Aggregate Nanofibers of Glycosylated Aza‐BODIPY for Synergetic Cell Membrane Disruption and Type I Photodynamic Therapy
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Self‐Assembly of Short Peptides Activates Specific ER‐Phagy and Induces Pyroptosis for Enhanced Tumor Immunotherapy
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In Situ Self‐Assembled J‐Aggregate Nanofibers of Glycosylated Aza‐BODIPY for Synergetic Cell Membrane Disruption and Type I Photodynamic Therapy
inferred← citeshttps://doi.org/10.1002/anie.202422874openalex-snapshot
Self‐Assembly of Short Peptides Activates Specific ER‐Phagy and Induces Pyroptosis for Enhanced Tumor Immunotherapy
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Pyroptosis, metabolism, and tumor immune microenvironment
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P2X7 is expressed on human innate‐like T lymphocytes and mediates susceptibility to ATP‐induced cell death
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Circumventing pyroptosis via hyperactivation shapes superior immune responses of human type 2 dendritic cells compared to type 3 dendritic cells
inferred← citeshttps://doi.org/10.1002/eji.202451053openalex-snapshot
Release of IL‐1β and IL‐18 in human primary bronchial epithelial cells exposed to cigarette smoke is independent of NLRP3
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Saikosaponin‐D induces the pyroptosis of lung cancer by increasing ROS and activating the NF‐κB/NLRP3/caspase‐1/GSDMD pathway
inferred← citeshttps://doi.org/10.1002/jev2.12127openalex-snapshot
Inflammasome‐induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses
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C1qc Mediates Blood–Brain Barrier Disruption in a Mouse Model of Intracerebral Haemorrhage Through Microglia‐Derived Migrasomes
inferred← citeshttps://doi.org/10.1002/jlb.3mr0420-305ropenalex-snapshot
Multiple roles of caspase-8 in cell death, inflammation, and innate immunity
inferred← citeshttps://doi.org/10.1002/jlb.4mr0119-013ropenalex-snapshot
Guanylate-binding proteins at the crossroad of noncanonical inflammasome activation during bacterial infections
inferred← citeshttps://doi.org/10.1002/mco2.249openalex-snapshot
Role of pyroptosis in the pathogenesis and treatment of diseases
inferred← citeshttps://doi.org/10.1002/mco2.391openalex-snapshot
Inflammasome: structure, biological functions, and therapeutic targets
inferred← citeshttps://doi.org/10.1002/mco2.70010openalex-snapshot
Ferroptosis: mechanisms and therapeutic targets
inferred← citeshttps://doi.org/10.1002/mco2.70798openalex-snapshot
Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities
inferred← citeshttps://doi.org/10.1002/mco2.70915openalex-snapshot
Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets
inferred← citeshttps://doi.org/10.1002/path.5248openalex-snapshot
The pathological features of regulated necrosis
inferred← citeshttps://doi.org/10.1002/smll.202405496openalex-snapshot
Devising Biocompatible, NIR‐Activated Helical Pyroptosis Agents via 𝛑‐Twisting Strategy for Promoting Antitumor Immunity
inferred← citeshttps://doi.org/10.1007/978-1-0716-2449-4_14openalex-snapshot
Detection of Gasdermin Activation and Lytic Cell Death During Pyroptosis and Apoptosis
inferred← citeshttps://doi.org/10.1007/978-1-0716-2449-4_16openalex-snapshot
Non-apoptotic Cell Death Control of Neutrophil Extracellular Trap Formation
inferred← citeshttps://doi.org/10.1007/978-1-0716-3040-2_1openalex-snapshot
Molecular Mechanisms of Pyroptosis
inferred← citeshttps://doi.org/10.1007/978-1-0716-3040-2_14openalex-snapshot
Monitoring Calcium Fluxes and Lysosome Exocytosis During Pyroptosis
inferred← citeshttps://doi.org/10.1007/978-3-031-92785-0_8openalex-snapshot
For Better or Worse: The Impact of Necrotic Cell Death Modalities
inferred← citeshttps://doi.org/10.1007/978-981-96-3675-4_8openalex-snapshot
Cell Death in Atherosclerosis: Apoptosis? Or Necrosis? Or More?
inferred← citeshttps://doi.org/10.1007/s00005-023-00678-9openalex-snapshot
The Pyroptotic and Nonpyroptotic Roles of Gasdermins in Modulating Cancer Progression and Their Perspectives on Cancer Therapeutics
inferred← citeshttps://doi.org/10.1007/s00018-022-04211-7openalex-snapshot
ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system
inferred← citeshttps://doi.org/10.1007/s00401-022-02528-yopenalex-snapshot
Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons
inferred← citeshttps://doi.org/10.1007/s00401-024-02722-0openalex-snapshot
Regulated cell death and its role in Alzheimer’s disease and amyotrophic lateral sclerosis
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Low ALIX expression might promote mucosal inflammation in the colon of patients with ulcerative colitis, possibly by promoting pyroptosis: an in silico analysis
inferred← citeshttps://doi.org/10.1007/s10238-025-01740-wopenalex-snapshot
Regulation of pyroptosis in diabetic nephropathy by long non-coding and circular RNAs
inferred← citeshttps://doi.org/10.1007/s10495-023-01906-5openalex-snapshot
New prospects of cancer therapy based on pyroptosis and pyroptosis inducers
inferred← citeshttps://doi.org/10.1007/s10495-024-01966-1openalex-snapshot
FSP1-mediated ferroptosis in cancer: from mechanisms to therapeutic applications
inferred← citeshttps://doi.org/10.1007/s10495-025-02133-wopenalex-snapshot
Disrupting membranes, controlling cell fate: the role of pore-forming proteins in cell death and therapy
inferred← citeshttps://doi.org/10.1007/s10495-025-02161-6openalex-snapshot
Comprehensive analysis of regulated cell death pathways: intrinsic disorder, protein–protein interactions, and cross-pathway communication
inferred← citeshttps://doi.org/10.1007/s10495-025-02250-6openalex-snapshot
Advances in the research of gasdermin-dependent pyroptosis mechanisms and therapeutic targets in inflammatory diseases
inferred← citeshttps://doi.org/10.1007/s10528-023-10446-1openalex-snapshot
A Novel Defined Necroptosis-Related Genes Prognostic Signature for Predicting Prognosis and Treatment of Osteosarcoma
inferred← citeshttps://doi.org/10.1007/s10528-023-10583-7openalex-snapshot
Identification and Immune Characteristics Study of Pyroptosis‑Related Genes in Endometriosis
inferred← citeshttps://doi.org/10.1007/s10753-021-01439-6openalex-snapshot
The Signaling Pathways Regulating NLRP3 Inflammasome Activation
inferred← citeshttps://doi.org/10.1007/s10815-026-03799-0openalex-snapshot
A novel PCOS susceptibility gene, cathepsin B, might be likely to contribute to the pyroptosis of ovarian granulosa cells
inferred← citeshttps://doi.org/10.1007/s11033-021-06252-wopenalex-snapshot
Repairing plasma membrane damage in regulated necrotic cell death
inferred← citeshttps://doi.org/10.1007/s11302-026-10140-yopenalex-snapshot
The P2X7 receptor/NLRP3 inflammasome signaling axis in sepsis: molecular mechanisms, organ-specific pathophysiology, and emerging therapeutic strategies
inferred← citeshttps://doi.org/10.1007/s12026-022-09286-9openalex-snapshot
Insights into inflammasome regulation: cellular, molecular, and pathogenic control of inflammasome activation
inferred← citeshttps://doi.org/10.1007/s12035-024-04255-9openalex-snapshot
Pyroptosis Signature Gene CHMP4B Regulates Microglia Pyroptosis by Inhibiting GSDMD in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1007/s12035-024-04359-2openalex-snapshot
Targeting NLRP3 Inflammasomes: A Trojan Horse Strategy for Intervention in Neurological Disorders
inferred← citeshttps://doi.org/10.1007/s12035-026-06055-9openalex-snapshot
Gasdermin D in Neurodegenerative Diseases: Pathogenic Roles and Therapeutic Perspectives
inferred← citeshttps://doi.org/10.1007/s12079-020-00564-5openalex-snapshot
Gasdermin family: a promising therapeutic target for cancers and inflammation-driven diseases
inferred← citeshttps://doi.org/10.1007/s12265-022-10224-1openalex-snapshot
Polymyxin B Reduces Brain Injury in Ischemic Stroke Rat Through a Mechanism Involving Targeting ESCRT-III Machinery and RIPK1/RIPK3/MLKL Pathway
inferred← citeshttps://doi.org/10.1007/s12640-026-00824-zopenalex-snapshot
Targeting Gasdermins for Therapeutic Interventions in Central Nervous System Injury
inferred← citeshttps://doi.org/10.1007/s12672-025-03508-wopenalex-snapshot
From gum inflammation to oral cancers: pyroptosis as the molecular torchbearer in periodontitis-driven carcinogenesis
inferred← citeshttps://doi.org/10.1007/s13402-026-01232-3openalex-snapshot
Regulated cell death programs shaping cancer therapy
inferred← citeshttps://doi.org/10.1007/s13577-025-01343-3openalex-snapshot
Potential of potentiometric biosensors for the study of ion influx and efflux via gasdermin pores in plasma membrane in pyroptosis: a hypothesis
inferred← citeshttps://doi.org/10.1007/s40291-024-00718-wopenalex-snapshot
Beyond Death: Unmasking the Intricacies of Apoptosis Escape
inferred← citeshttps://doi.org/10.1007/s44411-026-00528-yopenalex-snapshot
Critical Insight into the Relationship and Dynamic Complexity of Pyroptosis and Inflammation in Cancer Microenvironment: Potential Multifaceted Intervention Points in Tumor Immunotherapy
inferred← citeshttps://doi.org/10.1016/b978-0-12-816768-7.00028-4openalex-snapshot
IL-1 mediated autoinflammatory diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-821618-7.00136-xopenalex-snapshot
ESCRTing Around the Cell
inferred← citeshttps://doi.org/10.1016/b978-0-323-89911-6.00003-0openalex-snapshot
ESCRT-mediated plasma membrane shaping
inferred← citeshttps://doi.org/10.1016/b978-0-323-91802-2.00006-2openalex-snapshot
Inflammasome formation and triggers
inferred← citeshttps://doi.org/10.1016/b978-0-323-91802-2.00015-3openalex-snapshot
Inflammasomes in cigarette smoke- or ozone-induced lung diseases
inferred← citeshttps://doi.org/10.1016/b978-0-323-91802-2.00028-1openalex-snapshot
Cellular signaling, molecular activation, and regulation of the noncanonical inflammasome
inferred← citeshttps://doi.org/10.1016/b978-0-323-91802-2.00032-3openalex-snapshot
Apoptosis and inflammasome regulation
inferred← citeshttps://doi.org/10.1016/b978-0-323-91802-2.00036-0openalex-snapshot
Regulation of neutrophil NETosis by inflammasome
inferred← citeshttps://doi.org/10.1016/b978-0-443-15447-8.00007-6openalex-snapshot
Damage-associated molecular patterns as metabolic regulators of innate immunity
inferred← citeshttps://doi.org/10.1016/bs.abl.2019.01.006openalex-snapshot
Tuning the way to die: implications of membrane perturbations in necroptosis
inferred← citeshttps://doi.org/10.1016/bs.ai.2023.03.002openalex-snapshot
Regulation of gasdermins in pyroptosis and cytokine release
inferred← citeshttps://doi.org/10.1016/bs.ctm.2019.07.003openalex-snapshot
Signaling pathways involved in adaptive responses to cell membrane disruption
inferred← citeshttps://doi.org/10.1016/bs.mcb.2026.02.019openalex-snapshot
Measurement and quantification of macrophage lytic cell death by kinetic microscopy
inferred← citeshttps://doi.org/10.1016/bs.mcb.2026.05.003openalex-snapshot
The heat-ramp method to study regulated cell death in a pathogenic yeast Cryptococcus neoformans
inferred← citeshttps://doi.org/10.1016/bs.mie.2019.04.024openalex-snapshot
Monitoring gasdermin pore formation in vitro
inferred← citeshttps://doi.org/10.1016/j.actbio.2022.11.017openalex-snapshot
Cell mechanical responses to subcellular perturbations generated by ultrasound and targeted microbubbles
inferred← citeshttps://doi.org/10.1016/j.apsb.2020.07.003openalex-snapshot
The role of lysosome in regulated necrosis
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.06.026openalex-snapshot
Pyroptosis: Induction and inhibition strategies for immunotherapy of diseases
inferred← citeshttps://doi.org/10.1016/j.bbadva.2023.100109openalex-snapshot
WITHDRAWN: CHMP4B and VSP4A reverse GSDMD-mediated pyroptosis by cell membrane remodeling in endometrial carcinoma
inferred← citeshttps://doi.org/10.1016/j.bbagen.2023.130497openalex-snapshot
CHMP4B and VSP4A reverse GSDMD-mediated pyroptosis by cell membrane remodeling in endometrial carcinoma
inferred← citeshttps://doi.org/10.1016/j.bbcan.2021.188635openalex-snapshot
The multifaceted roles of gasdermins in cancer biology and oncologic therapies
inferred← citeshttps://doi.org/10.1016/j.bbi.2020.07.042openalex-snapshot
Acute stress induces the rapid and transient induction of caspase-1, gasdermin D and release of constitutive IL-1β protein in dorsal hippocampus
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.11.110openalex-snapshot
ESCRT-III–dependent membrane repair blocks ferroptosis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2020.07.127openalex-snapshot
The Ca2+-dependent pathway contributes to changes in the subcellular localization and extracellular release of interleukin-33
inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.149394openalex-snapshot
Caspase-4 has a role in cell division in epithelial cells through actin depolymerization
inferred← citeshttps://doi.org/10.1016/j.bbrc.2024.149978openalex-snapshot
The protease caspase-1: Activation pathways and functions
inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114585openalex-snapshot
Targeting the gasdermin D as a strategy for ischemic stroke therapy
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116348openalex-snapshot
Insight into the structure, function and the tumor suppression effect of gasdermin E
inferred← citeshttps://doi.org/10.1016/j.bcp.2026.117763openalex-snapshot
The role of gasdermin D-mediated pyroptosis in hepatic ischemia–reperfusion injury and prediction of the therapeutic natural products
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2024.02.022openalex-snapshot
Self-adaptive pyroptosis-responsive nanoliposomes block pyroptosis in autoimmune inflammatory diseases
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115914openalex-snapshot
Pyroptosis in septic lung injury: Interactions with other types of cell death
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116863openalex-snapshot
The role of pyroptosis in metabolism and metabolic disease
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117367openalex-snapshot
Overview of pyroptosis mechanism and in-depth analysis of cardiomyocyte pyroptosis mediated by NF-κB pathway in heart failure
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118286openalex-snapshot
Pyroptosis in acute respiratory distress syndrome and pulmonary fibrosis
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119180openalex-snapshot
Macrophage extracellular traps in autoimmunity: In vivo definition, pathogenic circuits, and therapeutic targeting
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119591openalex-snapshot
Estrogen /progesterone receptor-gasdermin E axis links hormone signalling to pyroptotic cell death, anti-tumour immunity and response to chemotherapy in breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.brainres.2021.147639openalex-snapshot
Defining (and blocking) neuronal death in Parkinson’s disease: Does it matter what we call it?
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2020.10.009openalex-snapshot
Targeting pyroptosis to regulate ischemic stroke injury: Molecular mechanisms and preclinical evidences
inferred← citeshttps://doi.org/10.1016/j.canlet.2023.216413openalex-snapshot
Epigenetic regulation of pyroptosis in cancer: Molecular pathogenesis and targeting strategies
inferred← citeshttps://doi.org/10.1016/j.canlet.2026.218860openalex-snapshot
Radiation-induced cell-death states in cancer: Toward biomarker-guided radioimmunotherapy
inferred← citeshttps://doi.org/10.1016/j.ceb.2019.04.005openalex-snapshot
The ESCRT-machinery: closing holes and expanding roles
inferred← citeshttps://doi.org/10.1016/j.ceb.2020.06.002openalex-snapshot
ESCRT puts its thumb on the nanoscale: Fixing tiny holes in endolysosomes
inferred← citeshttps://doi.org/10.1016/j.ceb.2026.102632openalex-snapshot
A current view on molecular mechanisms and machineries driving unconventional pathways of protein secretion
inferred← citeshttps://doi.org/10.1016/j.ceca.2023.102778openalex-snapshot
Calcium as a master regulator of ferroptosis and other types of regulated necrosis
inferred← citeshttps://doi.org/10.1016/j.cej.2026.182142openalex-snapshot
A pH-responsive nanoplatform targets pyroptosis reversibility to enhance chemo-immunotherapy in gastric cancer
inferred← citeshttps://doi.org/10.1016/j.cell.2019.04.024openalex-snapshot
The Coming Decade of Cell Death Research: Five Riddles
inferred← citeshttps://doi.org/10.1016/j.cell.2021.06.028openalex-snapshot
Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
inferred← citeshttps://doi.org/10.1016/j.cell.2023.04.025openalex-snapshot
A 360° view of the inflammasome: Mechanisms of activation, cell death, and diseases
inferred← citeshttps://doi.org/10.1016/j.cell.2023.05.027openalex-snapshot
Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine
inferred← citeshttps://doi.org/10.1016/j.cell.2024.03.031openalex-snapshot
Synthetic protein circuits for programmable control of mammalian cell death
inferred← citeshttps://doi.org/10.1016/j.cell.2024.11.018openalex-snapshot
Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells
inferred← citeshttps://doi.org/10.1016/j.cellsig.2019.109388openalex-snapshot
IL-18/IL-18BP and IL-22/IL-22BP: Two interrelated couples with therapeutic potential
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.03.100openalex-snapshot
Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.12.066openalex-snapshot
Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.108826openalex-snapshot
Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.108887openalex-snapshot
Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.108998openalex-snapshot
Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.109012openalex-snapshot
Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.109750openalex-snapshot
Inappropriate use of antibiotics exacerbates inflammation through OMV-induced pyroptosis in MDR Klebsiella pneumoniae infection
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111205openalex-snapshot
Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111374openalex-snapshot
The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.113349openalex-snapshot
The SNARE complex formed by RIC-4/SEC-22/SYX-2 promotes C. elegans epidermal wound healing
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.113700openalex-snapshot
Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115233openalex-snapshot
Gasdermin D mediates a fast transient release of ATP after NLRP3 inflammasome activation before ninjurin 1-induced lytic cell death
inferred← citeshttps://doi.org/10.1016/j.chembiol.2024.03.009openalex-snapshot
Strategies of bacterial detection by inflammasomes
inferred← citeshttps://doi.org/10.1016/j.chembiol.2024.04.006openalex-snapshot
Metabolism-inflammasome crosstalk shapes innate and adaptive immunity
inferred← citeshttps://doi.org/10.1016/j.chembiol.2026.04.011openalex-snapshot
Kinetic control of macrophage death by PTM-turnover crosstalk in infection and inflammation
inferred← citeshttps://doi.org/10.1016/j.chembiol.2026.05.003openalex-snapshot
Beyond the veil of cell death
inferred← citeshttps://doi.org/10.1016/j.chemphyslip.2020.105026openalex-snapshot
Pore-forming proteins: From defense factors to endogenous executors of cell death
inferred← citeshttps://doi.org/10.1016/j.chom.2020.02.004openalex-snapshot
TMEM173 Drives Lethal Coagulation in Sepsis
inferred← citeshttps://doi.org/10.1016/j.clim.2019.06.008openalex-snapshot
CASP1 variants influence subcellular caspase-1 localization, pyroptosome formation, pro-inflammatory cell death and macrophage deformability
inferred← citeshttps://doi.org/10.1016/j.clnves.2025.100049openalex-snapshot
Targeting ferroptosis in cancer therapy: Mechanisms, strategies, and clinical applications
inferred← citeshttps://doi.org/10.1016/j.coi.2020.09.008openalex-snapshot
Necroptotic movers and shakers: cell types, inflammatory drivers and diseases
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2025.104909openalex-snapshot
Inflammatory cell death and leukemia treatment
inferred← citeshttps://doi.org/10.1016/j.csbj.2024.02.002openalex-snapshot
Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancer
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2025.05.005openalex-snapshot
The secretion of interleukin-1β
inferred← citeshttps://doi.org/10.1016/j.devcel.2019.10.025openalex-snapshot
Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal
inferred← citeshttps://doi.org/10.1016/j.devcel.2019.11.004openalex-snapshot
Prominin-2 Suppresses Ferroptosis Sensitivity
inferred← citeshttps://doi.org/10.1016/j.devcel.2021.12.015openalex-snapshot
Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis
inferred← citeshttps://doi.org/10.1016/j.devcel.2024.08.008openalex-snapshot
Cell death: Revisiting the roads to ruin
inferred← citeshttps://doi.org/10.1016/j.devcel.2026.05.014openalex-snapshot
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair
inferred← citeshttps://doi.org/10.1016/j.ejmech.2025.118171openalex-snapshot
Progress in small-molecule inhibitors of gasdermin D
inferred← citeshttps://doi.org/10.1016/j.exphem.2024.104214openalex-snapshot
Lethal and sublethal effects of programmed cell death pathways on hematopoietic stem cells
inferred← citeshttps://doi.org/10.1016/j.fct.2021.112771openalex-snapshot
Ubiquitinated gasdermin D mediates arsenic-induced pyroptosis and hepatic insulin resistance in rat liver
inferred← citeshttps://doi.org/10.1016/j.gene.2023.147888openalex-snapshot
RNA-seq revealed the anti-pyroptotic effect of suramin by suppressing NLRP3/caspase-1/GSDMD pathway in LPS-induced MH-S alveolar macrophages
inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e23004openalex-snapshot
Pyroptosis-related gene signature: A predictor for overall survival, immunotherapy response, and chemosensitivity in patients with pancreatic adenocarcinoma
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e24010openalex-snapshot
Triptolide attenuates cardiac remodeling by inhibiting pyroptosis and EndMT via modulating USP14/Keap1/Nrf2 pathway
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e30022openalex-snapshot
The role of FGF-21 in promoting diabetic wound healing by modulating high glucose-induced inflammation
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.140116openalex-snapshot
Hyaluronic acid-mediated targeted nano-modulators for activation of pyroptosis for cancer therapy through multichannel regulation of Ca2+ overload
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.142865openalex-snapshot
Non-coding RNAs modulate pyroptosis in diabetic cardiomyopathy: A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.imj.2022.09.001openalex-snapshot
The noncanonical inflammasome in health and disease
inferred← citeshttps://doi.org/10.1016/j.imlet.2021.04.002openalex-snapshot
Inflammasomes in dendritic cells: Friend or foe?
inferred← citeshttps://doi.org/10.1016/j.immuni.2018.12.032openalex-snapshot
Defying Death: The (W)hole Truth about the Fate of GSDMD Pores
inferred← citeshttps://doi.org/10.1016/j.immuni.2019.03.007openalex-snapshot
Cytokine Circuits in Cardiovascular Disease
inferred← citeshttps://doi.org/10.1016/j.immuni.2019.04.005openalex-snapshot
Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM
inferred← citeshttps://doi.org/10.1016/j.immuni.2019.08.005openalex-snapshot
Inflammasomes: Threat-Assessment Organelles of the Innate Immune System
inferred← citeshttps://doi.org/10.1016/j.immuni.2019.11.005openalex-snapshot
Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure
inferred← citeshttps://doi.org/10.1016/j.immuni.2022.07.013openalex-snapshot
Hold your horses! Reining in your fastest pores with caspase-7
inferred← citeshttps://doi.org/10.1016/j.immuni.2024.02.011openalex-snapshot
Gasdermin and MLKL necrotic cell death effectors: Signaling and diseases
inferred← citeshttps://doi.org/10.1016/j.immuni.2025.04.007openalex-snapshot
Inflammasome signaling in astrocytes modulates hippocampal plasticity
inferred← citeshttps://doi.org/10.1016/j.immuni.2025.06.019openalex-snapshot
Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine
inferred← citeshttps://doi.org/10.1016/j.immuni.2026.02.017openalex-snapshot
Cellular memory of sub-lethal stress
inferred← citeshttps://doi.org/10.1016/j.intimp.2021.108338openalex-snapshot
Isoliquiritigenin alleviates P. gingivalis-LPS/ATP-induced pyroptosis by inhibiting NF-κB/ NLRP3/GSDMD signals in human gingival fibroblasts
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.109875openalex-snapshot
SMSCs-derived sEV overexpressing miR-433-3p inhibits angiogenesis induced by sEV released from synoviocytes under triggering of ferroptosis
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112203openalex-snapshot
Ferroptosis in antitumor therapy: Unraveling regulatory mechanisms and immunogenic potential
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112386openalex-snapshot
An explanation of the role of pyroptosis playing in epilepsy
inferred← citeshttps://doi.org/10.1016/j.intimp.2026.117007openalex-snapshot
ESCRT-mediated membrane remodeling in cancer immune evasion and resistance to immunotherapy: mechanisms, therapeutic vulnerabilities, and translational implications
inferred← citeshttps://doi.org/10.1016/j.intimp.2026.117118openalex-snapshot
Catalpol ameliorates intervertebral disc degeneration by suppressing NP cell Pyroptosis via the NF-ĸB pathway
inferred← citeshttps://doi.org/10.1016/j.isci.2021.103518openalex-snapshot
Long non-coding RNA MIAT is involved in the regulation of pyroptosis in diabetic cardiomyopathy via targeting miR-214-3p
inferred← citeshttps://doi.org/10.1016/j.isci.2026.115663openalex-snapshot
Pyroptosis in endometritis: Molecular mechanisms, pathogenic roles, and therapeutic opportunities
inferred← citeshttps://doi.org/10.1016/j.it.2019.09.005openalex-snapshot
Emerging Activators and Regulators of Inflammasomes and Pyroptosis
inferred← citeshttps://doi.org/10.1016/j.it.2021.04.001openalex-snapshot
Emerging mechanisms of immunocoagulation in sepsis and septic shock
inferred← citeshttps://doi.org/10.1016/j.it.2021.05.001openalex-snapshot
NLRP3 inflammasomes that induce antitumor immunity
inferred← citeshttps://doi.org/10.1016/j.it.2025.11.007openalex-snapshot
Neuronal inflammasomes: balancing immunity, neuroinflammation, and homeostasis
inferred← citeshttps://doi.org/10.1016/j.jaci.2021.04.018openalex-snapshot
Structures and functions of the inflammasome engine
inferred← citeshttps://doi.org/10.1016/j.jare.2024.05.010openalex-snapshot
Quercetin, a natural flavonoid, protects against hepatic ischemia–reperfusion injury via inhibiting Caspase-8/ASC dependent macrophage pyroptosis
inferred← citeshttps://doi.org/10.1016/j.jbc.2023.102908openalex-snapshot
Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis
inferred← citeshttps://doi.org/10.1016/j.jbc.2025.110557openalex-snapshot
10 things you wish you knew about inflammatory caspases: A holistic review of their biochemistry, activation, and signalling
inferred← citeshttps://doi.org/10.1016/j.jbc.2026.113370openalex-snapshot
Systematic genetic analysis of GSDMD, GSDME, and MLKL in PANoptosis
inferred← citeshttps://doi.org/10.1016/j.jbc.2026.113547openalex-snapshot
The phosphate exporter XPR1 promotes gasdermin D–independent mature IL-1β secretion
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.11.009openalex-snapshot
Hepatocytes Are Resistant to Cell Death From Canonical and Non-Canonical Inflammasome-Activated Pyroptosis
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.12.006openalex-snapshot
Burning, but Not Dying: the Failure of Pyroptotic Cell Death in Hepatocytes
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.04.054openalex-snapshot
Biodegradable pyroptosis inducer with multienzyme-mimic activity kicks up reactive oxygen species storm for sensitizing immunotherapy
inferred← citeshttps://doi.org/10.1016/j.jmb.2019.11.016openalex-snapshot
Nucleic Acid Sensors and Programmed Cell Death
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