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Microglial autophagy–associated phagocytosis is essential for recovery from neuroinflammation
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3 of the 84 references listed on this page are in the Retraction Watch database as retracted (export 2026-11-04): 10.1038/nature17950 (notice 2022-08-31), 10.1038/ncb3192 (notice 2024-03-04), 10.1073/pnas.1113421108 (notice 2025-08-04).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/eji.200636837openalex-snapshot
Blockade of TREM‐2 exacerbates experimental autoimmune encephalomyelitis
inferredcites →https://doi.org/10.1002/eji.201948342openalex-snapshot
Comparative analysis of CreER transgenic mice for the study of brain macrophages: A case study
inferredcites →https://doi.org/10.1002/glia.22298openalex-snapshot
Comparison of polarization properties of human adult microglia and blood‐derived macrophages
inferredcites →https://doi.org/10.1007/s12311-013-0489-4openalex-snapshot
The Salih Ataxia Mutation Impairs Rubicon Endosomal Localization
inferredcites →https://doi.org/10.1016/0167-8140(96)01705-7openalex-snapshot
Time course of radiation-induced apoptosis in the adult rat spinal cord
inferredcites →https://doi.org/10.1016/j.cell.2013.11.030openalex-snapshot
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
inferredcites →https://doi.org/10.1016/j.cell.2015.12.057openalex-snapshot
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
inferredcites →https://doi.org/10.1016/j.cell.2017.05.018openalex-snapshot
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
inferredcites →https://doi.org/10.1016/j.cell.2017.07.023openalex-snapshot
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease
inferredcites →https://doi.org/10.1016/j.cell.2019.05.056openalex-snapshot
LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease
inferredcites →https://doi.org/10.1016/j.celrep.2016.05.039openalex-snapshot
TMEM16F Regulates Spinal Microglial Function in Neuropathic Pain States
inferredcites →https://doi.org/10.1016/j.chom.2018.01.018openalex-snapshot
The β2 Integrin Mac-1 Induces Protective LC3-Associated Phagocytosis of Listeria monocytogenes
inferredcites →https://doi.org/10.1016/j.expneurol.2013.08.002openalex-snapshot
Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage
inferredcites →https://doi.org/10.1016/j.immuni.2017.08.008openalex-snapshot
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
inferredcites →https://doi.org/10.1016/j.immuni.2017.08.015openalex-snapshot
A Tale of Two Genes: Microglial Apoe and Trem2
inferredcites →https://doi.org/10.1016/j.intimp.2016.09.017openalex-snapshot
The role of autophagy in the pathogenesis of systemic lupus erythematosus
inferredcites →https://doi.org/10.1016/j.neuroscience.2018.10.030openalex-snapshot
Role of the CD200-CD200R Axis During Homeostasis and Neuroinflammation
inferredcites →https://doi.org/10.1016/j.pep.2003.11.016openalex-snapshot
Single-step purification and refolding of recombinant mouse and human myelin oligodendrocyte glycoprotein and induction of EAE in mice
inferredcites →https://doi.org/10.1016/s0140-6736(18)30475-6openalex-snapshot
Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study
inferredcites →https://doi.org/10.1016/s1474-4422(14)70256-xopenalex-snapshot
Pathological mechanisms in progressive multiple sclerosis
inferredcites →https://doi.org/10.1038/nature17950openalex-snapshot
RETRACTED ARTICLE: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells
inferredcites →https://doi.org/10.1038/ncb3192openalex-snapshot
RETRACTED ARTICLE: Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins
inferredcites →https://doi.org/10.1038/ncomms15750openalex-snapshot
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
inferredcites →https://doi.org/10.1038/ni.3196openalex-snapshot
The transcription factor TFEB acts as a molecular switch that regulates exogenous antigen-presentation pathways
inferredcites →https://doi.org/10.1038/s41467-018-07295-7openalex-snapshot
Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells
inferredcites →https://doi.org/10.1038/s41467-019-08729-6openalex-snapshot
Suppression of autophagic activity by Rubicon is a signature of aging
inferredcites →https://doi.org/10.1038/s41467-019-12516-8openalex-snapshot
Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus
inferredcites →https://doi.org/10.1038/s41586-019-0924-xopenalex-snapshot
Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
inferredcites →https://doi.org/10.1038/s41586-019-1404-zopenalex-snapshot
Neuronal vulnerability and multilineage diversity in multiple sclerosis
inferredcites →https://doi.org/10.1038/s41590-018-0091-5openalex-snapshot
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling
inferredcites →https://doi.org/10.1073/pnas.1113421108openalex-snapshot
RETRACTED: Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells
inferredcites →https://doi.org/10.1073/pnas.1708018114openalex-snapshot
Metal transporter Slc39a10 regulates susceptibility to inflammatory stimuli by controlling macrophage survival
inferredcites →https://doi.org/10.1074/jbc.m112.382812openalex-snapshot
Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens
inferredcites →https://doi.org/10.1080/15548627.2018.1434373openalex-snapshot
TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis
inferredcites →https://doi.org/10.1080/15548627.2018.1446626openalex-snapshot
Release the autophage brake on inflammation: The MAPK14/p38α-ULK1 pedal
inferredcites →https://doi.org/10.1080/15548627.2018.1474313openalex-snapshot
Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency
inferredcites →https://doi.org/10.1080/15548627.2018.1535292openalex-snapshot
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration
inferredcites →https://doi.org/10.1083/jcb.200412022openalex-snapshot
Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice
inferredcites →https://doi.org/10.1084/jem.20021546openalex-snapshot
CD36 Mediates the Innate Host Response to β-Amyloid
inferredcites →https://doi.org/10.1084/jem.20132477openalex-snapshot
Differential roles of microglia and monocytes in the inflamed central nervous system
inferredcites →https://doi.org/10.1084/jem.20141656openalex-snapshot
Inefficient clearance of myelin debris by microglia impairs remyelinating processes
inferredcites →https://doi.org/10.1093/brain/awq076openalex-snapshot
Evidence for a two-stage disability progression in multiple sclerosis
inferredcites →https://doi.org/10.1093/brain/awx113openalex-snapshot
Loss of ‘homeostatic’ microglia and patterns of their activation in active multiple sclerosis
inferredcites →https://doi.org/10.1093/brain/awx250openalex-snapshot
Long-term disability progression in primary progressive multiple sclerosis: a 15-year study
inferredcites →https://doi.org/10.1093/cvr/cvt117openalex-snapshot
Vimentin is an endogenous ligand for the pattern recognition receptor Dectin-1
inferredcites →https://doi.org/10.1093/hmg/ddt343openalex-snapshot
Combining genetic mapping with genome-wide expression in experimental autoimmune encephalomyelitis highlights a gene network enriched for T cell functions and candidate genes regulating autoimmunity
inferredcites →https://doi.org/10.1093/nar/gki475openalex-snapshot
WebGestalt: an integrated system for exploring gene sets in various biological contexts
inferredcites →https://doi.org/10.1111/febs.14354openalex-snapshot
Rubicon: LC 3‐associated phagocytosis and beyond
inferredcites →https://doi.org/10.1111/j.1460-9568.1997.tb01694.xopenalex-snapshot
The Role of the Mouse Macrophage Scavenger Receptor in Myelin Phagocytosis
inferredcites →https://doi.org/10.1111/j.1471-4159.1973.tb07519.xopenalex-snapshot
MYELINATION IN RAT BRAIN: METHOD OF MYELIN ISOLATION1
inferredcites →https://doi.org/10.1111/j.1750-3639.1998.tb00194.xopenalex-snapshot
Autoimmunity to Myelin Oligodendrocyte Glycoprotein in Rats Mimics the Spectrum of Multiple Sclerosis Pathology
inferredcites →https://doi.org/10.1111/j.2517-6161.1995.tb02031.xopenalex-snapshot
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
inferredcites →https://doi.org/10.1126/science.1204592openalex-snapshot
TFEB Links Autophagy to Lysosomal Biogenesis
inferredcites →https://doi.org/10.1126/science.aan4183openalex-snapshot
Defective cholesterol clearance limits remyelination in the aged central nervous system
inferredcites →https://doi.org/10.1126/science.aat7554openalex-snapshot
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation
inferredcites →https://doi.org/10.1146/annurev.immunol.23.021704.115707openalex-snapshot
IMMUNOLOGY OF MULTIPLE SCLEROSIS
inferredcites →https://doi.org/10.1159/000358140openalex-snapshot
Crohn's Disease: Loss of Tolerance or a Disorder of Autophagy?
inferredcites →https://doi.org/10.1159/000370112openalex-snapshot
Autophagy Controls Acquisition of Aging Features in Macrophages
inferredcites →https://doi.org/10.1159/000479516openalex-snapshot
Older Age at Multiple Sclerosis Onset Is an Independent Factor of Poor Prognosis: A Population-Based Cohort Study
inferredcites →https://doi.org/10.1182/blood-2008-02-137398openalex-snapshot
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
inferredcites →https://doi.org/10.1182/blood-2008-04-151639openalex-snapshot
Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
inferredcites →https://doi.org/10.1186/1750-1172-9-68openalex-snapshot
LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1212/01.wnl.0000435551.90824.d0openalex-snapshot
Gray matter damage predicts the accumulation of disability 13 years later in MS
inferredcites →https://doi.org/10.1212/wnl.0b013e318230a17dopenalex-snapshot
Age and disability accumulation in multiple sclerosis
inferredcites →https://doi.org/10.1371/journal.pone.0021800openalex-snapshot
REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms
inferredcites →https://doi.org/10.1523/jneurosci.1569-12.2012openalex-snapshot
PPARγ/RXRα-Induced and CD36-Mediated Microglial Amyloid-β Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice
inferredcites →https://doi.org/10.1523/jneurosci.2615-05.2006openalex-snapshot
Myelin Impairs CNS Remyelination by Inhibiting Oligodendrocyte Precursor Cell Differentiation
inferredcites →https://doi.org/10.3389/fimmu.2017.00909openalex-snapshot
Anti-inflammatory Mechanisms Triggered by Apoptotic Cells during Their Clearance
inferredcites →https://doi.org/10.3389/fimmu.2018.02761openalex-snapshot
NLRX1 Facilitates Histoplasma capsulatum-Induced LC3-Associated Phagocytosis for Cytokine Production in Macrophages
inferredcites →https://doi.org/10.3389/fimmu.2019.00790openalex-snapshot
Phagocytosis in the Brain: Homeostasis and Disease
inferredcites →https://doi.org/10.3389/fnagi.2017.00194openalex-snapshot
Aging Microglia—Phenotypes, Functions and Implications for Age-Related Neurodegenerative Diseases
inferredcites →https://doi.org/10.3389/fnagi.2018.00004openalex-snapshot
Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications
inferredcites →https://doi.org/10.3389/fncel.2014.00152openalex-snapshot
Microglia change from a reactive to an age-like phenotype with the time in culture
inferredcites →https://doi.org/10.3389/fnmol.2018.00144openalex-snapshot
Microglial Phagocytosis and Its Regulation: A Therapeutic Target in Parkinson’s Disease?
inferredcites →https://doi.org/10.3390/ijms20010081openalex-snapshot
The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives
inferredcites →https://doi.org/10.4049/jimmunol.0801143openalex-snapshot
Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes
inferredcites →https://doi.org/10.4049/jimmunol.153.10.4349openalex-snapshot
Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice.
inferredcites →https://doi.org/10.4161/auto.25188openalex-snapshot
Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons
inferredcites →https://doi.org/10.4161/auto.29647openalex-snapshot
Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome
inferredcites →https://doi.org/10.4161/auto.7.1.13893openalex-snapshot
A quantitative assay for the monitoring of autophagosome accumulation in different phases of the cell cycle
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4795163openalex-extracted
The Microglial Response to Inhibition of Colony-Stimulating-Factor-1 Receptor Differs by Sex in Adult Mice
inferred← citeshttps://doi.org/10.1002/adma.202108435openalex-snapshot
Controlled Activation of TRPV1 Channels on Microglia to Boost Their Autophagy for Clearance of Alpha‐Synuclein and Enhance Therapy of Parkinson's Disease
inferred← citeshttps://doi.org/10.1002/advs.77117openalex-snapshot
A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair
inferred← citeshttps://doi.org/10.1002/cns.70881openalex-snapshot
Inhibition of Microglial TRPV1 Ameliorates Brain Injury After Intracerebral Hemorrhage by Suppressing AMPK / PINK1 ‐Mediated Mitophagy
inferred← citeshttps://doi.org/10.1002/cns.70984openalex-snapshot
CYP46A1 ‐Targeted Treatment Alleviates Long‐Term White Matter Injury Following Traumatic Brain Injury by Promoting Cholesterol Metabolic Clearance and Remyelination
inferred← citeshttps://doi.org/10.1002/ctm2.70462openalex-snapshot
Atg7 in CD4+ T cells improves intestinal mucosal inflammation by regulating Ets1‐mediated T cell differentiation
inferred← citeshttps://doi.org/10.1002/glia.24446openalex-snapshot
Prophylactic effect of chronic immunosuppression in a mouse model of CSF ‐1 receptor‐related leukoencephalopathy
inferred← citeshttps://doi.org/10.1002/glia.24602openalex-snapshot
Myelin debris phagocytosis in demyelinating disease
inferred← citeshttps://doi.org/10.1002/mco2.150openalex-snapshot
Autophagy in health and disease: From molecular mechanisms to therapeutic target
inferred← citeshttps://doi.org/10.1002/mco2.311openalex-snapshot
Modulation of the immunity and inflammation by autophagy
inferred← citeshttps://doi.org/10.1007/978-1-0716-3437-0_3openalex-snapshot
Studying Autophagy in Microglia: Overcoming the Obstacles
inferred← citeshttps://doi.org/10.1007/978-981-95-3945-1_12openalex-snapshot
Inflammatory Demyelination and Autophagic Dysfunction in Multiple Sclerosis
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Pathophysiological basis and promise of experimental therapies for Gulf War Illness, a chronic neuropsychiatric syndrome in veterans
inferred← citeshttps://doi.org/10.1007/s00441-021-03487-8openalex-snapshot
Loss-of-function manipulations to identify roles of diverse glia and stromal cells during CNS scar formation
inferred← citeshttps://doi.org/10.1007/s10753-025-02355-9openalex-snapshot
Autophagy-NLRP3 Inflammasome Crosstalk in Microglia: A Therapeutic Target for Multiple Sclerosis
inferred← citeshttps://doi.org/10.1007/s11064-022-03695-wopenalex-snapshot
Resveratrol Attenuated Manganese-Induced Learning and Memory Impairments in Mice Through PGC-1Alpha-Mediated Autophagy and Microglial M1/M2 Polarization
inferred← citeshttps://doi.org/10.1007/s11356-022-24292-yopenalex-snapshot
Lipopolysaccharide induces inflammatory microglial activation through CD147-mediated matrix metalloproteinase expression
inferred← citeshttps://doi.org/10.1007/s12031-021-01894-8openalex-snapshot
Caffeine Inhibits Activation of the NLRP3 Inflammasome via Autophagy to Attenuate Microglia-Mediated Neuroinflammation in Experimental Autoimmune Encephalomyelitis
inferred← citeshttps://doi.org/10.1007/s12035-024-03996-xopenalex-snapshot
Autophagy in Multiple Sclerosis: Phagocytosis and Autophagy of Oligodendrocyte Precursor Cells
inferred← citeshttps://doi.org/10.1007/s12035-025-05144-5openalex-snapshot
Quaking Protein in Myelin Maintenance and Regeneration in the Central Nervous System
inferred← citeshttps://doi.org/10.1007/s12264-023-01120-yopenalex-snapshot
The Multiple Roles of Autophagy in Neural Function and Diseases
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Trehalose’s untapped mechanisms in alzheimer’s: gut–brain–autophagy signalling beyond the usual targets
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Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles
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Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming
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PYGL-driven glycogenolysis impairs microglial autophagic flux via SNAP29 O-GlcNAcylation in Alzheimer's disease
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The roles of transient receptor potential vanilloid in autoimmune diseases
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Unlocking the therapeutic promise of miRNAs in promoting amyloid-β clearance for Alzheimer's disease
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Drug repurposing: Clemastine fumarate and neurodegeneration
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Recent advances of nanomaterials for intervention in Parkinson’s disease in the context of anti-inflammation
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Consequences and mechanisms of myelin debris uptake and processing by cells in the central nervous system
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FGF20 alleviates neuroinflammation in ischemic stroke by modulating microglial polarization via TREM2-TLR4/NF-κB pathway
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Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy
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The microglial response to inhibition of Colony-stimulating-factor-1 receptor by PLX3397 differs by sex in adult mice
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Autophagy in severe acute respiratory syndrome coronavirus 2 infection
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Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina
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Microglial senescence and epigenetic reprogramming in alzheimer's disease: An immunometabolic perspective
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Reactive nitrogen species as therapeutic targets for autophagy/mitophagy modulation to relieve neurodegeneration in multiple sclerosis: Potential application for drug discovery
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A critical role for microglia in regulating metabolic homeostasis and neural repair after spinal cord injury
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Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes
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Diosgenin alleviates neuropathic pain based on the enhancement of autophagy and promotion of M2 polarization
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Modulation of microglial metabolism facilitates regeneration in demyelination
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SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury
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Aurkb deficiency disrupts microglial development, homeostasis and hinders remyelination following cuprizone-induced demyelination
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NLRP6 governs hippocampal microglial phagocytosis to resist stress-induced depressive-like behaviors in mice and the intervention effect of bezafibrate
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Anti–IL-6R antibody treatment changes microglial phenotype in AQP4 peptide–immunized mice, leading to suppression of myelitis severity
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A bacterially engineered macrophage sponge as a neutralization decoy to treat bacterial infection
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Distinct olfactory mucosal macrophage populations mediate neuronal maintenance and pathogen defense
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The mechanism of disease progression by aging and age-related gut dysbiosis in multiple sclerosis
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Autophagy–exosome crosstalk in neurodegeneration: Mechanisms and therapeutic opportunities
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The regulation of microglia by aging and autophagy in multiple sclerosis
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PIM1-induced Drp1 phosphorylation disrupts microglial mitophagy and aggravates neuroinflammation
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Lipophagy: a new player in CNS disorders
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Local cholesterol metabolism orchestrates remyelination
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Next questions of autophagy in neurodegenerative diseases: From mechanisms to therapeutics
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Neuroinflammation-Modulating Agent SB1617 Enhances LC3-Associated Phagocytosis to Mitigate Tau Pathology
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Molecular, Biochemical, and Epigenetic Mechanisms Involved in Environmental Neurotoxicants Exposure Induced Premature Brain Aging with Central Focus on Pesticides Role
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Bionic Dormant Body of Timed Wake-Up for Bacteriotherapy in Vivo
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The role of glial autophagy in Alzheimer’s disease
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Cell death in multiple sclerosis
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Rubicon modulates neuroimmune responses following traumatic brain injury
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Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice
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LC3-associated phagocytosis promotes glial degradation of axon debris after injury in Drosophila models
inferred← citeshttps://doi.org/10.1038/s41467-023-40370-2openalex-snapshot
Microglial expression of CD83 governs cellular activation and restrains neuroinflammation in experimental autoimmune encephalomyelitis
inferred← citeshttps://doi.org/10.1038/s41467-023-44556-6openalex-snapshot
The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34
inferred← citeshttps://doi.org/10.1038/s41556-023-01158-0openalex-snapshot
Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence
inferred← citeshttps://doi.org/10.1038/s41556-023-01168-yopenalex-snapshot
Autophagy prevents microglial senescence
inferred← citeshttps://doi.org/10.1038/s41577-023-00907-4openalex-snapshot
Microglia regulation of central nervous system myelin health and regeneration
inferred← citeshttps://doi.org/10.1038/s41593-025-02161-4openalex-snapshot
TGFβ signaling mediates microglial resilience to spatiotemporally restricted myelin degeneration
inferred← citeshttps://doi.org/10.1038/s41598-025-10441-zopenalex-snapshot
Localized brain stimulation with mild magnetic hyperthermia promotes microglia activity towards reactive and autophagic phenotypes in vivo
inferred← citeshttps://doi.org/10.1039/d1nj03214copenalex-snapshot
A dual-channel fluorescent probe for monitoring pH changes in lysosomes during autophagy
inferred← citeshttps://doi.org/10.1073/pnas.2023418118openalex-snapshot
Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading
inferred← citeshttps://doi.org/10.1073/pnas.2209990120openalex-snapshot
Staged suppression of microglial autophagy facilitates regeneration in CNS demyelination by enhancing the production of linoleic acid
inferred← citeshttps://doi.org/10.1080/08916934.2024.2351872openalex-snapshot
New insight in treating autoimmune diseases by targeting autophagy
inferred← citeshttps://doi.org/10.1080/15548627.2022.2047343openalex-snapshot
Targeting lipophagy in macrophages improves repair in multiple sclerosis
inferred← citeshttps://doi.org/10.1080/15548627.2023.2165313openalex-snapshot
Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy
inferred← citeshttps://doi.org/10.1080/15548627.2023.2259281openalex-snapshot
The beneficial role of autophagy in multiple sclerosis: Yes or No?
inferred← citeshttps://doi.org/10.1080/15548627.2023.2277634openalex-snapshot
ATG5 (autophagy related 5) in microglia controls hippocampal neurogenesis in Alzheimer disease
inferred← citeshttps://doi.org/10.1080/21655979.2022.2052671openalex-snapshot
Protecting effect of emodin in experimental autoimmune encephalomyelitis mice by inhibiting microglia activation and inflammation via Myd88/PI3K/Akt/NF-κB signalling pathway
inferred← citeshttps://doi.org/10.1080/27694127.2022.2119743openalex-snapshot
Interactions of Autophagy and the Immune System in Health and Diseases
inferred← citeshttps://doi.org/10.1080/27694127.2025.2471677openalex-snapshot
Autophagy in alzheimer disease pathogenesis and its therapeutic values
inferred← citeshttps://doi.org/10.1084/jem.20230173openalex-snapshot
Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control
inferred← citeshttps://doi.org/10.1093/neuonc/noad257openalex-snapshot
Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma
inferred← citeshttps://doi.org/10.1101/2023.05.15.23289980openalex-snapshot
Identification of neuropathology-based subgroups in multiple sclerosis using a data-driven approach
inferred← citeshttps://doi.org/10.1101/2025.06.14.659704openalex-snapshot
Human placental stem cells induce a novel multiple myeloid cell-driven immunosuppressive program that ameliorates proinflammatory CNS pathology
inferred← citeshttps://doi.org/10.1101/2025.07.23.25331426openalex-snapshot
Identification of co-segregating RUBCN and KANK1 mutations in a UK ALS kindred
inferred← citeshttps://doi.org/10.1111/febs.15772openalex-snapshot
Complement cascade functions during brain development and neurodegeneration
inferred← citeshttps://doi.org/10.1111/febs.17192openalex-snapshot
Extracellular vesicles promote autophagy in human microglia through lipid raft‐dependent mechanisms
inferred← citeshttps://doi.org/10.1111/jnc.15984openalex-snapshot
Bilirubin impacts microglial autophagy via the Akt–mTOR signaling pathway
inferred← citeshttps://doi.org/10.1111/jnc.70384openalex-snapshot
Microglia at the Forefront: New Insights From the Glial Club South Cone Meeting 2025
inferred← citeshttps://doi.org/10.1111/jpi.12916openalex-snapshot
Melatonin prevents EAAC1 deletion‐induced retinal ganglion cell degeneration by inhibiting apoptosis and senescence
inferred← citeshttps://doi.org/10.1172/jci.insight.148719openalex-snapshot
CD47 antibody blockade suppresses microglia-dependent phagocytosis and monocyte transition to macrophages, impairing recovery in EAE
inferred← citeshttps://doi.org/10.1177/13872877261452179openalex-snapshot
Crocin alleviates neuroinflammation and glia-associated synaptic alterations through NRF2 after chronic cerebral hypoperfusion
inferred← citeshttps://doi.org/10.1186/s12944-024-02185-yopenalex-snapshot
MiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice
inferred← citeshttps://doi.org/10.1186/s12950-023-00349-8openalex-snapshot
Stem cell-derived brainstem mouse astrocytes obtain a neurotoxic phenotype in vitro upon neuroinflammation
inferred← citeshttps://doi.org/10.1186/s12964-026-02911-2openalex-snapshot
Gas6 restores microglial efferocytosis and limits neuroinflammation in neonatal hypoxic-ischemic encephalopathy by activating MerTK and the PI3K–Rac1 pathway
inferred← citeshttps://doi.org/10.1186/s12974-021-02200-4openalex-snapshot
Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice
inferred← citeshttps://doi.org/10.1186/s12974-023-02866-yopenalex-snapshot
Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration
inferred← citeshttps://doi.org/10.1186/s12974-024-03278-2openalex-snapshot
Senolytic treatment diminishes microglia and decreases severity of experimental autoimmune encephalomyelitis
inferred← citeshttps://doi.org/10.1186/s12974-024-03296-0openalex-snapshot
Fueling neurodegeneration: metabolic insights into microglia functions
inferred← citeshttps://doi.org/10.1186/s12974-026-03743-0openalex-snapshot
FGF4 activates FGFR1 - PI3K/AKT signaling to enhance Clec10a-mediated intracellular myelin debris processing and promote spinal cord repair
inferred← citeshttps://doi.org/10.1186/s13041-021-00794-7openalex-snapshot
Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response
inferred← citeshttps://doi.org/10.1186/s13073-025-01519-4openalex-snapshot
Single-nucleus transcriptomics reveals a distinct microglial state and increased MSR1-mediated phagocytosis as common features across dementia subtypes
inferred← citeshttps://doi.org/10.1186/s40478-026-02370-3openalex-snapshot
CSF1R inhibition following antibody mediated demyelination has limited impact on remyelination
inferred← citeshttps://doi.org/10.1523/eneuro.0183-20.2021openalex-snapshot
Deficiency of Microglial Autophagy Increases the Density of Oligodendrocytes and Susceptibility to Severe Forms of Seizures
inferred← citeshttps://doi.org/10.15252/embj.2021108863openalex-snapshot
Autophagy in major human diseases
inferred← citeshttps://doi.org/10.15252/embr.202154499openalex-snapshot
Myeloid cell‐specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation
inferred← citeshttps://doi.org/10.15252/msb.202110239openalex-snapshot
A systems‐level study reveals host‐targeted repurposable drugs against SARS‐CoV‐2 infection
inferred← citeshttps://doi.org/10.21037/atm-22-5159openalex-snapshot
BAG3 promotes autophagy and suppresses NLRP3 inflammasome activation in Parkinson’s disease
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3936707/v1openalex-snapshot
MiR-223 Enhances Lipophagy by Suppressing CTSB in Microglia Following Lysolecithin-Induced Demyelination in Mice
inferred← citeshttps://doi.org/10.21203/rs.3.rs-6578878/v1openalex-snapshot
P2Y6R-positive microglia sense the stress metabolite uridine and exacerbate photoreceptor degeneration in the retina
inferred← citeshttps://doi.org/10.2174/011570159x386374250623095520openalex-snapshot
Targeting the cGAS-STING Pathway: Modulating Inflammation, Oxidative Stress, and Autophagy for Novel Depression Therapies
inferred← citeshttps://doi.org/10.2174/1570159x19666210407150632openalex-snapshot
Autophagy & Phagocytosis in Neurological Disorders and their Possible Cross-talk
inferred← citeshttps://doi.org/10.32607/actanaturae.11830openalex-snapshot
Attenuating Neuronal Autophagy Alleviates Inflammatory Injury in OGD-Deprived Co-culture of HT22 with BV2
inferred← citeshttps://doi.org/10.3389/fchem.2026.1891677openalex-snapshot
Lysosomes as chemical and metabolic organizers of central nervous system injury and repair
inferred← citeshttps://doi.org/10.3389/fimmu.2020.620602openalex-snapshot
Assessing Autophagy in Microglia: A Two-Step Model to Determine Autophagosome Formation, Degradation, and Net Turnover
inferred← citeshttps://doi.org/10.3389/fimmu.2021.724108openalex-snapshot
Therapeutic Targeting of Immune Cell Autophagy in Multiple Sclerosis: Russian Roulette or Silver Bullet?
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1322842openalex-snapshot
Epigenetic regulation of autophagy in neuroinflammation and synaptic plasticity
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1775841openalex-snapshot
Focusing on microglial mitochondria-lysosome crosstalk and neuroinflammation underlying depression: from molecular pathways to potential therapeutic interventions
inferred← citeshttps://doi.org/10.3389/fnagi.2022.1023679openalex-snapshot
Microglial autophagy in cerebrovascular diseases
inferred← citeshttps://doi.org/10.3389/fnagi.2022.1039780openalex-snapshot
The role of microglial autophagy in Parkinson’s disease
inferred← citeshttps://doi.org/10.3389/fnagi.2026.1735696openalex-snapshot
Molecular mechanism of Alzheimer’s disease using integrated multi-omics
inferred← citeshttps://doi.org/10.3389/fnagi.2026.1884230openalex-snapshot
Dysfunction of lipid metabolism and lysosomal capacity: at the core of microglial aging?
inferred← citeshttps://doi.org/10.3389/fncel.2021.811852openalex-snapshot
Alzheimer’s Disease: From Pathogenesis to Mesenchymal Stem Cell Therapy – Bridging the Missing Link
inferred← citeshttps://doi.org/10.3389/fncel.2023.1182621openalex-snapshot
Regulation of microglia polarization after cerebral ischemia
inferred← citeshttps://doi.org/10.3389/fnmol.2021.749737openalex-snapshot
Psychological Stress as a Risk Factor for Accelerated Cellular Aging and Cognitive Decline: The Involvement of Microglia-Neuron Crosstalk
inferred← citeshttps://doi.org/10.3389/fnmol.2023.1299314openalex-snapshot
Immune response of BV-2 microglial cells is impacted by peroxisomal beta-oxidation
inferred← citeshttps://doi.org/10.3389/fphar.2021.770610openalex-snapshot
Fluoxetine Potentiates Phagocytosis and Autophagy in Microglia
inferred← citeshttps://doi.org/10.3390/cells13242069openalex-snapshot
Distinct UPR and Autophagic Functions Define Cell-Specific Responses to Proteotoxic Stress in Microglial and Neuronal Cell Lines
inferred← citeshttps://doi.org/10.3390/genes15081027openalex-snapshot
Identification of Autophagy-Related Biomarkers and Diagnostic Model in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3390/ijms22020740openalex-snapshot
Mitophagy Modulation, a New Player in the Race against ALS
inferred← citeshttps://doi.org/10.3390/ijms232214455openalex-snapshot
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study
inferred← citeshttps://doi.org/10.3390/ijms232314997openalex-snapshot
Neuroinflammation and Autophagy in Parkinson’s Disease—Novel Perspectives
inferred← citeshttps://doi.org/10.3390/jcm10061239openalex-snapshot
Roles of Microglial Ion Channel in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.3390/molecules30061251openalex-snapshot
Anthraquinones and Aloe Vera Extracts as Potential Modulators of Inflammaging Mechanisms: A Translational Approach from Autoimmune to Onco-Hematological Diseases
inferred← citeshttps://doi.org/10.34133/research.0130openalex-snapshot
Transcranial Magneto-Acoustic Stimulation Attenuates Synaptic Plasticity Impairment through the Activation of Piezo1 in Alzheimer’s Disease Mouse Model
inferred← citeshttps://doi.org/10.4103/1673-5374.358612openalex-snapshot
Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis
inferred← citeshttps://doi.org/10.4103/1673-5374.382227openalex-snapshot
Autophagy in neural stem cells and glia for brain health and diseases
inferred← citeshttps://doi.org/10.4103/nrr.nrr-d-24-01405openalex-snapshot
Generation and clearance of myelin debris after spinal cord injury
inferred← citeshttps://doi.org/10.4103/tcmj.tcmj_213_25openalex-snapshot
Microglial activation and lysosomal dysfunction in hemorrhagic stroke
inferred← citeshttps://doi.org/10.6084/m9.figshare.14728529openalex-snapshot
Additional file 1 of Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response
inferred← citeshttps://doi.org/10.64898/2026.01.31.703045openalex-snapshot
Functional border-associated macrophages limit Alzheimer’s Disease progression
inferred← citeshttps://doi.org/10.70675/65eec3acz4916z460cza447zbbae94dd481eopenalex-snapshot
Étude de la physiopathologie de l'épilepsie du lobe temporal : analyse détaillée de la myélinisation des interneurones à parvalbumine et des réactions gliales
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