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Mechanism of Action and Limited Cross-Resistance of New Lipopeptide MX-2401

https://doi.org/10.1128/aac.00170-11
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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ChemInform Abstract: Friulimicins: Novel Lipopeptide Antibiotics with Peptidoglycan Synthesis Inhibiting Activity from Actinoplanes friuliensis sp. nov. Part 2. Isolation and Structural Characterization.
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Water Suppression That Works. Excitation Sculpting Using Arbitrary Wave-Forms and Pulsed-Field Gradients
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Parametrisation of time-averaged distance restraints in MD simulations
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Effect of divalent cations on the structure of the antibiotic daptomycin
inferredcites →https://doi.org/10.1016/0006-291x(79)91797-2openalex-snapshot
Amphomycin inhibits phospho-N-acetylmuramyl-pentapeptide translocase in peptidoglycan synthesis of Bacillus
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Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins
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Time-dependent distance restraints in molecular dynamics simulations
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Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes
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Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy
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Studies on bacterial cell wall inhibitors
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Mode of action of the new antibiotic for Gram-positive pathogens daptomycin: Comparison with cationic antimicrobial peptides and lipopeptides
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NMR structural studies of the antibiotic lipopeptide daptomycin in DHPC micelles
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Oligomerization of daptomycin on membranes
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Structural Transitions as Determinants of the Action of the Calcium-Dependent Antibiotic Daptomycin
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A Revised Pathway Proposed for Staphylococcus aureus Wall Teichoic Acid Biosynthesis Based on In Vitro Reconstitution of the Intracellular Steps
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Lipid-specific binding of the calcium-dependent antibiotic daptomycin leads to changes in lipid polymorphism of model membranes
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Novel antimicrobial lipopeptides with long in vivo half-lives
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An oldie but a goodie – cell wall biosynthesis as antibiotic target pathway
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Rapid test for distinguishing membrane-active antibacterial agents
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Amphomycin inhibition of mannose and GlcNAc incorporation into lipid-linked saccharides.
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Engineering a Cell-Free Murein Biosynthetic Pathway: Combinatorial Enzymology in Drug Discovery
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The GROMOS Biomolecular Simulation Program Package
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Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
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Natural products to drugs: daptomycin and related lipopeptide antibiotics
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Role of lipid‐bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics
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Investigation of exchange processes by two-dimensional NMR spectroscopy
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Molecular dynamics with coupling to an external bath
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A generalized reaction field method for molecular dynamics simulations
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Interaction of Cationic Antimicrobial Peptides with Model Membranes
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Inhibition of Daptomycin by Pulmonary Surfactant: In Vitro Modeling and Clinical Impact
inferredcites →https://doi.org/10.1093/glycob/11.3.25ropenalex-snapshot
Formation of the glycan chains in the synthesis of bacterial peptidoglycan
inferredcites →https://doi.org/10.1093/glycob/cwi016openalex-snapshot
NMR study of the preferred membrane orientation of polyisoprenols (dolichol) and the impact of their complex with polyisoprenyl recognition sequence peptides on membrane structure
inferredcites →https://doi.org/10.1107/s0907444905017270openalex-snapshot
Structure of the lipopeptide antibiotic tsushimycin
inferredcites →https://doi.org/10.1111/j.1365-2958.2004.04149.xopenalex-snapshot
In vitro assembly of a complete, pentaglycine interpeptide bridge containing cell wall precursor (lipid II‐Gly 5 ) of Staphylococcus aureus
inferredcites →https://doi.org/10.1126/science.1185723openalex-snapshot
Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II
inferredcites →https://doi.org/10.1128/aac.00238-10openalex-snapshot
In Vivo Pharmacodynamics of New Lipopeptide MX-2401
inferredcites →https://doi.org/10.1128/aac.00322-11openalex-snapshot
Antimicrobial Properties of MX-2401, an Expanded-Spectrum Lipopeptide Active in the Presence of Lung Surfactant
inferredcites →https://doi.org/10.1128/aac.01040-08openalex-snapshot
The Lipopeptide Antibiotic Friulimicin B Inhibits Cell Wall Biosynthesis through Complex Formation with Bactoprenol Phosphate
inferredcites →https://doi.org/10.1128/aac.47.8.2538-2544.2003openalex-snapshot
Correlation of Daptomycin Bactericidal Activity and Membrane Depolarization in Staphylococcus aureus
inferredcites →https://doi.org/10.1128/aem.02750-06openalex-snapshot
Assessment and Interpretation of Bacterial Viability by Using the LIVE/DEAD BacLight Kit in Combination with Flow Cytometry
inferredcites →https://doi.org/10.1128/jb.170.5.2197-2201.1988openalex-snapshot
murH, a new genetic locus in Escherichia coli involved in cell wall peptidoglycan biosynthesis
inferredcites →https://doi.org/10.1128/jb.173.11.3425-3431.1991openalex-snapshot
Analysis of murein and murein precursors during antibiotic-induced lysis of Escherichia coli
inferredcites →https://doi.org/10.7164/antibiotics.35.1216openalex-snapshot
Studies on bacterial cell wall inhibitors. X. Properties of phospho-N-acetylmuramoyl-pentapeptide-transferase in peptidoglycan synthesis of Bacillus megaterium and its inhibition by amphomycin.
inferredcites →https://doi.org/10.7164/antibiotics.41.1093openalex-snapshot
Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: The synthesis and evaluation of daptomycin (LY146032).
inferredcites →https://doi.org/10.7164/antibiotics.53.807openalex-snapshot
Friulimicins: Novel Lipopeptide Antibiotics with Peptidoglycan Synthesis Inhibiting Activity from Actinoplanes friuliensis sp. nov. I. Taxonomic Studies of the Producing Microorganism and Fermentation.
inferredcites →https://doi.org/10.7164/antibiotics.53.816openalex-snapshot
Friulimicins. Novel Lipopeptide Antibiotics with Peptidoglycan Synthesis Inhibiting Activity from Actinoplanes friuliensis sp. nov. II. Isolation and Structural Characterization.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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