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Kinetics of Influenza A Virus Infection in Humans

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Outgoing claims: the papers this work cites, builds on, or argues with.

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A simple cellular automaton model for influenza A viral infections

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HLA-RESTRICTED VIRUS-SPECIFIC CYTOTOXIC T-LYMPHOCYTE RESPONSES TO LIVE AND INACTIVATED INFLUENZA VACCINES

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Modelling how ribavirin improves interferon response rates in hepatitis C virus infection

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Lung Defense Mechanisms

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Inhaled Zanamivir for the Prevention of Influenza in Families

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Human and avian influenza viruses target different cell types in cultures of human airway epithelium

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Viral dynamics in hepatitis B virus infection.

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Nasal Cytokine and Chemokine Responses in Experimental Influenza A Virus Infection: Results of a Placebo‐Controlled Trial of Intravenous Zanamivir Treatment

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The Impact of Influenza Epidemics on Hospitalizations

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Differences in Viral Dynamics between Genotypes 1 and 2 of Hepatitis C Virus

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Production of Interferon in Volunteers Infected with Asian Influenza

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Interferon Bioassay: Reduction in Yield of Myxovirus Neuraminidases

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Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA

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HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

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Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-α Therapy

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Antiviral Actions of Interferons

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Influenza A Virus NS1 Protein Prevents Activation of NF-κB and Induction of Alpha/Beta Interferon

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HOW CELLS RESPOND TO INTERFERONS

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Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense.

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Bootstrap Methods for Standard Errors, Confidence Intervals, and Other Measures of Statistical Accuracy

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Virus-Induced Interferon Production by Human Macrophages

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On the Role of CD8 T Cells in the Control of Persistent Infections

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Chemical kinetics of the development of coronaviral infection in the human body: Critical conditions, toxicity mechanisms, “thermoheliox”, and “thermovaccination”

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A percolation phase transition controls complement protein coating of surfaces

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Modeling of innate immune responses of cells for vaccine production

inferred← citeshttps://doi.org/10.1016/j.chom.2016.01.011openalex-snapshot

Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus

inferred← citeshttps://doi.org/10.1016/j.coisb.2018.10.005openalex-snapshot

Validated models of immune response to virus infection

inferred← citeshttps://doi.org/10.1016/j.ddmod.2007.09.001openalex-snapshot

In silico modeling in infectious disease

inferred← citeshttps://doi.org/10.1016/j.ejps.2017.05.070openalex-snapshot

A human challenge model for respiratory syncytial virus kinetics, the pharmacological effect of a novel fusion inhibitor, and the modelling of symptoms scores

inferred← citeshttps://doi.org/10.1016/j.ejps.2026.107481openalex-snapshot

Experimental and virus-specific drivers of EC50 variability in antiviral assays evaluated using mathematical modeling

inferred← citeshttps://doi.org/10.1016/j.epidem.2010.10.001openalex-snapshot

High infectivity and pathogenicity of influenza A virus via aerosol and droplet transmission

inferred← citeshttps://doi.org/10.1016/j.epidem.2011.11.001openalex-snapshot

A new approach to characterising infectious disease transmission dynamics from sentinel surveillance: Application to the Italian 2009–2010 A/H1N1 influenza pandemic

inferred← citeshttps://doi.org/10.1016/j.epidem.2020.100406openalex-snapshot

Quantifying mechanistic traits of influenza viral dynamics using in vitro data

inferred← citeshttps://doi.org/10.1016/j.epidem.2021.100454openalex-snapshot

Estimation of the incubation period of COVID-19 using viral load data

inferred← citeshttps://doi.org/10.1016/j.epidem.2025.100843openalex-snapshot

Modelling the dynamics of SARS-CoV-2 during the first 14 days of infection

inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e21591openalex-snapshot

Rapid detection of human influenza A viruses by HFman probe-based loop-mediated isothermal amplification assays

inferred← citeshttps://doi.org/10.1016/j.hsr.2024.100201openalex-snapshot

Deciphering the intricacies of immune system dysfunction and its impact on diabetes mellitus: Revisiting the communication strategies to manage diabetes mellitus

inferred← citeshttps://doi.org/10.1016/j.idm.2017.04.002openalex-snapshot

In-host modeling

inferred← citeshttps://doi.org/10.1016/j.idm.2021.02.005openalex-snapshot

Within-host model of respiratory virus shedding and antibody response to H9N2 avian influenza virus vaccination and infection in chickens

inferred← citeshttps://doi.org/10.1016/j.idm.2025.07.003openalex-snapshot

Should public health policy exempt cases with low viral load from isolation during an epidemic?: a modelling study

inferred← citeshttps://doi.org/10.1016/j.ifacol.2015.12.135openalex-snapshot

Identifiability Challenges in Mathematical Models of Viral Infectious Diseases**This work was supported by iMed - the Helmholtz Initiative on Pesonalized Medicine.

inferred← citeshttps://doi.org/10.1016/j.ifacol.2019.02.001openalex-snapshot

Bacterial Pneumonia Fate Decisions

inferred← citeshttps://doi.org/10.1016/j.ifacol.2019.12.243openalex-snapshot

Strain-Specific Immune Response to Influenza Virus Infection

inferred← citeshttps://doi.org/10.1016/j.ifacol.2025.08.001openalex-snapshot

Reconstructing Governing Equations of Influenza Virus Dynamics from Incomplete Measurements

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Effectiveness of oseltamivir in reduction of complications and 30-day mortality in severe seasonal influenza infection

inferred← citeshttps://doi.org/10.1016/j.ijantimicag.2022.106606openalex-snapshot

Mechanistic Models of COVID-19: Insights into Disease Progression, Vaccines, and Therapeutics

inferred← citeshttps://doi.org/10.1016/j.ijantimicag.2024.107308openalex-snapshot

Host immunomodulation strategies to combat pandemic-associated antimicrobial-resistant secondary bacterial infections

inferred← citeshttps://doi.org/10.1016/j.ijid.2011.12.008openalex-snapshot

Effectiveness of a new bioequivalent formulation of oseltamivir (Enfluvir®) on 2010–2011 seasonal influenza viruses: an open phase IV study

inferred← citeshttps://doi.org/10.1016/j.ijid.2021.01.011openalex-snapshot

Effectiveness of Oseltamivir in reducing 30-day readmissions and mortality among patients with severe seasonal influenza in Australian hospitalized patients

inferred← citeshttps://doi.org/10.1016/j.ijid.2024.107034openalex-snapshot

Association of viral loads of influenza A (H3N2) with age and care setting on presentation—a prospective study during the 2022-2023 influenza season in Spain

inferred← citeshttps://doi.org/10.1016/j.immuno.2023.100021openalex-snapshot

The race to understand immunopathology in COVID-19: Perspectives on the impact of quantitative approaches to understand within-host interactions

inferred← citeshttps://doi.org/10.1016/j.ins.2008.11.012openalex-snapshot

Agent-based modeling of host–pathogen systems: The successes and challenges

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Impulsive optimal control for drug treatment of influenza A virus in the host with impulsive-axis equivalent model

inferred← citeshttps://doi.org/10.1016/j.isci.2022.104448openalex-snapshot

Modeling explains prolonged SARS-CoV-2 nasal shedding relative to lung shedding in remdesivir-treated rhesus macaques

inferred← citeshttps://doi.org/10.1016/j.isci.2024.109421openalex-snapshot

Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle “OP7”

inferred← citeshttps://doi.org/10.1016/j.it.2008.11.001openalex-snapshot

The race between infection and immunity: how do pathogens set the pace?

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Lung aerosol dynamics of airborne influenza A virus-laden droplets and the resultant immune system responses: An in silico study

inferred← citeshttps://doi.org/10.1016/j.jcrc.2008.02.003openalex-snapshot

Equation-based models of dynamic biological systems

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Viral load dynamics in intubated patients with COVID-19 admitted to the intensive care unit

inferred← citeshttps://doi.org/10.1016/j.jfma.2010.10.001openalex-snapshot

Viral load and clinical features in children infected with seasonal influenza B in 2006/2007

inferred← citeshttps://doi.org/10.1016/j.jinf.2024.106303openalex-snapshot

Modelling multiplex testing for outbreak control

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A simulation framework to investigate in vitro viral infection dynamics

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Probing the effects of the well-mixed assumption on viral infection dynamics

inferred← citeshttps://doi.org/10.1016/j.jtbi.2007.02.004openalex-snapshot

Simple scaling laws for influenza A rise time, duration, and severity

inferred← citeshttps://doi.org/10.1016/j.jtbi.2008.05.031openalex-snapshot

Modeling amantadine treatment of influenza A virus in vitro

inferred← citeshttps://doi.org/10.1016/j.jtbi.2010.05.036openalex-snapshot

Phenotypic differences in viral immune escape explained by linking within-host dynamics to host-population immunity

inferred← citeshttps://doi.org/10.1016/j.jtbi.2010.10.017openalex-snapshot

Neuraminidase inhibitors for treatment of human and avian strain influenza: A comparative modeling study

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Estimation of the incubation period of influenza A (H1N1-2009) among imported cases: Addressing censoring using outbreak data at the origin of importation

inferred← citeshttps://doi.org/10.1016/j.jtbi.2012.06.020openalex-snapshot

Evolution of viral life-cycle in response to cytotoxic T lymphocyte-mediated immunity

inferred← citeshttps://doi.org/10.1016/j.jtbi.2013.03.024openalex-snapshot

Towards multiscale modeling of influenza infection

inferred← citeshttps://doi.org/10.1016/j.jtbi.2014.01.008openalex-snapshot

Modeling inoculum dose dependent patterns of acute virus infections

inferred← citeshttps://doi.org/10.1016/j.jtbi.2015.03.017openalex-snapshot

The inflammatory response to influenza A virus (H1N1): An experimental and mathematical study

inferred← citeshttps://doi.org/10.1016/j.jtbi.2015.03.033openalex-snapshot

Predicting pathogen-specific CD8 T cell immune responses from a modeling approach

inferred← citeshttps://doi.org/10.1016/j.jtbi.2015.07.003openalex-snapshot

Quantifying relative within-host replication fitness in influenza virus competition experiments

inferred← citeshttps://doi.org/10.1016/j.jtbi.2018.01.012openalex-snapshot

Intermittent treatment of severe influenza

inferred← citeshttps://doi.org/10.1016/j.jtbi.2018.07.029openalex-snapshot

Modeling of fusion inhibitor treatment of RSV in African green monkeys

inferred← citeshttps://doi.org/10.1016/j.jtbi.2019.01.011openalex-snapshot

Superinfection and cell regeneration can lead to chronic viral coinfections

inferred← citeshttps://doi.org/10.1016/j.jtbi.2019.110026openalex-snapshot

Spatio-temporal dynamics of Host-Virus competition: A model study of influenza A

inferred← citeshttps://doi.org/10.1016/j.jtbi.2020.110266openalex-snapshot

An approximate solution of the interferon-dependent viral kinetics model of influenza

inferred← citeshttps://doi.org/10.1016/j.jtbi.2020.110320openalex-snapshot

A within-host mathematical model of H9N2 avian influenza infection and type-I interferon response pathways in chickens

inferred← citeshttps://doi.org/10.1016/j.jtbi.2020.110492openalex-snapshot

Modelling within-host macrophage dynamics in influenza virus infection

inferred← citeshttps://doi.org/10.1016/j.jtbi.2021.110749openalex-snapshot

The role of syncytia during viral infections

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Mathematical modelling of SARS-CoV-2 infection of human and animal host cells reveals differences in the infection rates and delays in viral particle production by infected cells

inferred← citeshttps://doi.org/10.1016/j.jtbi.2021.110896openalex-snapshot

Modeling the dynamics of Usutu virus infection in birds

inferred← citeshttps://doi.org/10.1016/j.jtbi.2021.110918openalex-snapshot

A multiscale multicellular spatiotemporal model of local influenza infection and immune response

inferred← citeshttps://doi.org/10.1016/j.jtbi.2021.110962openalex-snapshot

The role of a programmatic immune response on the evolution of pathogen traits

inferred← citeshttps://doi.org/10.1016/j.jtbi.2022.111091openalex-snapshot

The dynamics of relapses during treatment switch in relapsing-remitting multiple sclerosis

inferred← citeshttps://doi.org/10.1016/j.jtbi.2022.111370openalex-snapshot

Effect of cellular regeneration and viral transmission mode on viral spread

inferred← citeshttps://doi.org/10.1016/j.jtbi.2023.111447openalex-snapshot

Simplified within-host and Dose–response Models of SARS-CoV-2

inferred← citeshttps://doi.org/10.1016/j.jtbi.2023.111449openalex-snapshot

Multiple cohort study of hospitalized SARS-CoV-2 in-host infection dynamics: Parameter estimates, identifiability, sensitivity and the eclipse phase profile

inferred← citeshttps://doi.org/10.1016/j.jtbi.2023.111491openalex-snapshot

A target-cell limited model can reproduce influenza infection dynamics in hosts with differing immune responses

inferred← citeshttps://doi.org/10.1016/j.jtbi.2023.111592openalex-snapshot

Choice of spatial discretisation influences the progression of viral infection within multicellular tissues

inferred← citeshttps://doi.org/10.1016/j.jtbi.2024.111898openalex-snapshot

Modeling the CD8＋ T cell immune response to influenza infection in adult and aged mice

inferred← citeshttps://doi.org/10.1016/j.jtbi.2024.111959openalex-snapshot

Exploring the treatment of SARS-CoV-2 with modified vesicular stomatitis virus

inferred← citeshttps://doi.org/10.1016/j.jtbi.2025.112061openalex-snapshot

Efficient coupling of within-and between-host infectious disease dynamics

inferred← citeshttps://doi.org/10.1016/j.jtbi.2025.112184openalex-snapshot

The Role of Nutrition in Virus Dynamics in Vector-Borne Viral Infections

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Intracellular ISG-virus interactions determine viral infection severity and persistence

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Thermodynamic effect of RNA virus infection on the human cardiovascular system

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A comparison of methods for extracting influenza viral titer characteristics

inferred← citeshttps://doi.org/10.1016/j.matcom.2016.10.002openalex-snapshot

The logistic growth model as an approximating model for viral load measurements of influenza A virus

inferred← citeshttps://doi.org/10.1016/j.mbs.2012.04.008openalex-snapshot

Alternative to Ritt’s pseudodivision for finding the input-output equations of multi-output models

inferred← citeshttps://doi.org/10.1016/j.mbs.2018.03.011openalex-snapshot

Numerical schemes for solving and optimizing multiscale models with age of hepatitis C virus dynamics

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Stochastic dynamics in a time-delayed model for autoimmunity

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Data-driven models for replication kinetics of Orthohantavirus infections

inferred← citeshttps://doi.org/10.1016/j.mbs.2023.109011openalex-snapshot

Topological data analysis of antibody dynamics of severe and non-severe patients with COVID-19

inferred← citeshttps://doi.org/10.1016/j.mbs.2023.109052openalex-snapshot

The role of Type I interferons in the pathogenesis of foot-and-mouth disease virus in cattle: A mathematical modelling analysis

inferred← citeshttps://doi.org/10.1016/j.mbs.2023.109129openalex-snapshot

Different routes of infection of H5N1 lead to changes in infecting time

inferred← citeshttps://doi.org/10.1016/j.mbs.2025.109467openalex-snapshot

Bistability between acute and chronic states in a Model of Hepatitis B Virus Dynamics

inferred← citeshttps://doi.org/10.1016/j.meegid.2011.03.018openalex-snapshot

Computational analysis and modeling the effectiveness of ‘Zanamivir’ targeting neuraminidase protein in pandemic H1N1 strains

inferred← citeshttps://doi.org/10.1016/j.meegid.2011.10.019openalex-snapshot

Biased mutational pattern and quasispecies hypothesis in H5N1 virus

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