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Comparative evaluation of RT-PCR and antigen-based rapid diagnostic tests (Ag-RDTs) for SARS-CoV-2 detection: performance, variant specificity, and clinical implications

https://doi.org/10.1128/spectrum.00073-24
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Applied Logistic Regression
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Performance of a novel diagnostic assay for rapid SARS-CoV-2 antigen detection in nasopharynx samples
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Clinical significance of measuring serum cytokine levels as inflammatory biomarkers in adult and pediatric COVID-19 cases: A review
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Performance of a rapid antigen test for SARS-CoV-2 in Kenya
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Association of hypertension, diabetes, stroke, cancer, kidney disease, and high-cholesterol with COVID-19 disease severity and fatality: A systematic review
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Performance of SARS-CoV-2 rapid antigen test compared with real-time RT-PCR in asymptomatic individuals
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Prospective analytical performance evaluation of the QuickNavi™-COVID19 Ag for asymptomatic individuals
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How is immunosuppressive status affecting children and adults in SARS-CoV-2 infection? A systematic review
inferredcites →https://doi.org/10.1016/j.jinf.2021.04.009openalex-snapshot
Performance characteristics of five antigen-detecting rapid diagnostic test (Ag-RDT) for SARS-CoV-2 asymptomatic infection: a head-to-head benchmark comparison
inferredcites →https://doi.org/10.1016/j.tmaid.2020.101942openalex-snapshot
Comparative evaluation of four rapid SARS-CoV-2 antigen detection tests using universal transport medium
inferredcites →https://doi.org/10.1016/s2666-5247(21)00302-5openalex-snapshot
SARS-CoV-2 antigen-detecting rapid tests for the delta variant
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Temporal dynamics in viral shedding and transmissibility of COVID-19
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‘Test, re-test, re-test’: using inaccurate tests to greatly increase the accuracy of COVID-19 testing
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SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients
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Utility of Antigen-Based Rapid Diagnostic Test for Detection of SARS-CoV-2 Virus in Routine Hospital Settings
inferredcites →https://doi.org/10.1101/2020.03.07.20032524openalex-snapshot
Diagnosis of Acute Respiratory Syndrome Coronavirus 2 Infection by Detection of Nucleocapsid Protein
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Use cases for COVID-19 screening and surveillance with rapid antigen-detecting tests: a systematic review
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Evaluation of a Rapid Diagnostic Assay for Detection of SARS-CoV-2 Antigen in Nasopharyngeal Swabs
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Analytical Sensitivity of Eight Different SARS-CoV-2 Antigen-Detecting Rapid Tests for Omicron-BA.1 Variant
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Two-Period Study Results from a Large Italian Hospital Laboratory Attesting SARS-CoV-2 Variant PCR Assay Evolution
inferredcites →https://doi.org/10.11613/bm.2012.031openalex-snapshot
Interrater reliability: the kappa statistic
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Performance of antigen testing for diagnosis of COVID-19: a direct comparison of a lateral flow device to nucleic acid amplification based tests
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Trends of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody prevalence in selected regions across Ghana
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Field evaluation of the performance of seven Antigen Rapid diagnostic tests for the diagnosis of SARs-CoV-2 virus infection in Uganda
inferredcites →https://doi.org/10.17504/protocols.io.q26g7y32kgwz/v1openalex-snapshot
Isolation and Amplification of SARS-CoV-2 RNA from Nasopharyngeal Specimen v1
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Clinical Evaluation of Two Rapid Antigen Tests for Severe Acute Respiratory Syndrome Coronavirus 2 Detection
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An Update on Molecular Diagnostics for COVID-19
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Development and Potential Usefulness of the COVID-19 Ag Respi-Strip Diagnostic Assay in a Pandemic Context
inferredcites →https://doi.org/10.3389/fmicb.2022.810576openalex-snapshot
Performance of SARS-CoV-2 Antigen-Detecting Rapid Diagnostic Tests for Omicron and Other Variants of Concern
inferredcites →https://doi.org/10.3390/biom11030425openalex-snapshot
COVID-19 Rapid Antigen Test as Screening Strategy at Points of Entry: Experience in Lazio Region, Central Italy, August–October 2020
inferredcites →https://doi.org/10.3390/diagnostics11112105openalex-snapshot
Rapid, Cheap, and Effective COVID-19 Diagnostics for Africa
inferredcites →https://doi.org/10.3390/v13050908openalex-snapshot
Diagnostic Performance of Ag-RDTs and NAAT for SARS-CoV2 Identification in Symptomatic Patients in Catalonia
inferredcites →https://doi.org/10.7717/peerj.10801openalex-snapshot
Evaluation of two fluorescence immunoassays for the rapid detection of SARS-CoV-2 antigen—new tool to detect infective COVID-19 patients
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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.3897/rio.11.e152094zenodo-depositor-declared
Enhancing diagnostic sensitivity: Investigating molecular mechanisms of Antigen Rapid Diagnostic Test (AgRDTs) variability across SARS-CoV-2 variants
inferred← citeshttps://doi.org/10.1007/978-981-95-0618-7_5openalex-snapshot
Rolling out COVID-19 Rapid Detection Test Point of Care Diagnoses in Managing and Curbing COVID-19 in Ghana
inferred← citeshttps://doi.org/10.1016/j.microc.2025.114455openalex-snapshot
Ultrasensitive electrochemical biosensor using Carboxylated graphitic carbon nitride-nanogold composite for SARS-CoV-2 receptor binding protein
inferred← citeshttps://doi.org/10.1016/j.snb.2025.139324openalex-snapshot
A portable, electromagnetically-driven microfluidic system for molecular diagnosis of SARS-CoV-2 and Influenza A/B viruses
inferred← citeshttps://doi.org/10.1155/tbed/5701806openalex-snapshot
Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases
inferred← citeshttps://doi.org/10.1360/ssv-2024-0304openalex-snapshot
Research progress in the application of microfluidic chip <?A3B2 pi6?>technology for infectious disease diagnosis
inferred← citeshttps://doi.org/10.3390/diagnostics16060830openalex-snapshot
Evaluation of Flu A/B, SARS-CoV-2, and RSV Antigen Combo Rapid Test in Hospitalized Children Under Two Years of Age
inferred← citeshttps://doi.org/10.3390/metabo16030158openalex-snapshot
Untargeted Sweat and Sebum Volatilomics by HS-SPME-GC/ToF-MS for the Identification of SARS-CoV-2-Associated Biomarkers
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