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PPARα Ligands as Antitumorigenic and Antiangiogenic Agents
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1098-2744(200011)29:3<134::aid-mc2>3.0.co;2-fopenalex-snapshot
Activators of peroxisome proliferator-activated receptor-? partially inhibit mouse skin tumor promotion
inferredcites →https://doi.org/10.1002/ijc.20519openalex-snapshot
An overview of the effect of linoleic and conjugated‐linoleic acids on the growth of several human tumor cell lines
inferredcites →https://doi.org/10.1002/ijc.22115openalex-snapshot
Intestinal‐specific PPARγ deficiency enhances tumorigenesis in ApcMin/+ mice
inferredcites →https://doi.org/10.1002/ijc.23004openalex-snapshot
PPARα and PP2A are involved in the proapoptotic effect of conjugated linoleic acid on human hepatoma cell line SK‐HEP‐1
inferredcites →https://doi.org/10.1002/jcp.20738openalex-snapshot
Apoptosis induced by troglitazone is both peroxisome proliferator‐activated receptor‐γ‐ and ERK‐dependent in human non‐small lung cancer cells
inferredcites →https://doi.org/10.1002/mc.10061openalex-snapshot
Peroxisome proliferator–activated receptor α in the human breast cancer cell lines MCF‐7 and MDA‐MB‐231
inferredcites →https://doi.org/10.1007/s00018-003-2322-6openalex-snapshot
Fenofibrate inhibits angiogenesis in vitro and in vivo
inferredcites →https://doi.org/10.1007/s00109-005-0678-9openalex-snapshot
Peroxisome proliferator-activated receptor-α and liver cancer: where do we stand?
inferredcites →https://doi.org/10.1007/s00403-004-0479-yopenalex-snapshot
Inhibition of melanoma metastases by fenofibrate
inferredcites →https://doi.org/10.1016/0076-6879(90)87045-5openalex-snapshot
[43] Cytochrome P-450 arachidonate oxygenase
inferredcites →https://doi.org/10.1016/0092-8674(94)90006-xopenalex-snapshot
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
inferredcites →https://doi.org/10.1016/j.coph.2006.03.012openalex-snapshot
PPARs and other nuclear receptors in inflammation
inferredcites →https://doi.org/10.1016/j.ctrv.2004.04.004openalex-snapshot
Peroxisome proliferator-activated receptor-γ ligands as cell-cycle modulators
inferredcites →https://doi.org/10.1016/j.pharmthera.2005.11.003openalex-snapshot
From endothelium-derived hyperpolarizing factor (EDHF) to angiogenesis: Epoxyeicosatrienoic acids (EETs) and cell signaling
inferredcites →https://doi.org/10.1016/j.prostaglandins.2006.05.003openalex-snapshot
Epoxyeicosatrienoic acids, cell signaling and angiogenesis
inferredcites →https://doi.org/10.1016/j.tox.2007.09.030openalex-snapshot
PPARα: Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators
inferredcites →https://doi.org/10.1016/j.vph.2005.11.014openalex-snapshot
Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications
inferredcites →https://doi.org/10.1016/s0002-9149(01)01486-2openalex-snapshot
Plasma vascular endothelial growth factor and its receptor Flt-1 in patients with hyperlipidemia and atherosclerosis and the effects of fluvastatin or fenofibrate
inferredcites →https://doi.org/10.1016/s0006-291x(02)00385-6openalex-snapshot
PPAR activators inhibit endothelial cell migration by targeting Akt
inferredcites →https://doi.org/10.1016/s0022-2275(20)32049-6openalex-snapshot
Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase
inferredcites →https://doi.org/10.1016/s0027-5107(99)00232-8openalex-snapshot
Central role of PPARα in the mechanism of action of hepatocarcinogenic peroxisome proliferators
inferredcites →https://doi.org/10.1016/s0300-483x(02)00275-5openalex-snapshot
PPARα and the regulation of cell division and apoptosis
inferredcites →https://doi.org/10.1016/s0303-7207(02)00098-9openalex-snapshot
The peroxisome proliferator-activated receptor α (PPARα): role in hepatocarcinogenesis
inferredcites →https://doi.org/10.1016/s0960-0760(03)00214-0openalex-snapshot
Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation
inferredcites →https://doi.org/10.1016/s1097-2765(00)80210-5openalex-snapshot
PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance
inferredcites →https://doi.org/10.1016/s1357-2725(02)00025-0openalex-snapshot
Peroxisome proliferator-activated receptor β expression in human breast epithelial cell lines of tumorigenic and non-tumorigenic origin
inferredcites →https://doi.org/10.1038/2036openalex-snapshot
Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
inferredcites →https://doi.org/10.1038/34178openalex-snapshot
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
inferredcites →https://doi.org/10.1038/35013000openalex-snapshot
Roles of PPARs in health and disease
inferredcites →https://doi.org/10.1038/358771a0openalex-snapshot
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
inferredcites →https://doi.org/10.1038/nm1278openalex-snapshot
Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption
inferredcites →https://doi.org/10.1038/nrc1254openalex-snapshot
Peroxisome-proliferator-activated receptors and cancers: complex stories
inferredcites →https://doi.org/10.1056/nejm198711123172001openalex-snapshot
Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia
inferredcites →https://doi.org/10.1056/nejm199803263381302openalex-snapshot
Effect of Troglitazone in Insulin-Treated Patients with Type II Diabetes Mellitus
inferredcites →https://doi.org/10.1056/nejm199908053410604openalex-snapshot
Gemfibrozil for the Secondary Prevention of Coronary Heart Disease in Men with Low Levels of High-Density Lipoprotein Cholesterol
inferredcites →https://doi.org/10.1073/pnas.0500153102openalex-snapshot
Concurrent suppression of hyperlipidemia and intestinal polyp formation by NO-1886, increasing lipoprotein lipase activity in Min mice
inferredcites →https://doi.org/10.1073/pnas.0607948103openalex-snapshot
Crosstalk between peroxisome proliferator-activated receptor δ and VEGF stimulates cancer progression
inferredcites →https://doi.org/10.1073/pnas.0711281105openalex-snapshot
PPARα agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition
inferredcites →https://doi.org/10.1073/pnas.91.15.7355openalex-snapshot
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.
inferredcites →https://doi.org/10.1074/jbc.274.13.9116openalex-snapshot
Peroxisome Proliferator-activated Receptor γ Ligands Are Potent Inhibitors of Angiogenesis in Vitro and in Vivo
inferredcites →https://doi.org/10.1074/jbc.m110806200openalex-snapshot
Cytochrome P450 2C9-induced Endothelial Cell Proliferation Involves Induction of Mitogen-activated Protein (MAP) Kinase Phosphatase-1, Inhibition of the c-Jun N-terminal Kinase, and Up-regulation of Cyclin D1
inferredcites →https://doi.org/10.1074/jbc.m305385200openalex-snapshot
11,12-Epoxyeicosatrienoic Acid-induced Inhibition of FOXO Factors Promotes Endothelial Proliferation by Down-Regulating p27
inferredcites →https://doi.org/10.1074/jbc.m501730200openalex-snapshot
Characterization of 5,6- and 8,9-Epoxyeicosatrienoic Acids (5,6- and 8,9-EET) as Potent in Vivo Angiogenic Lipids
inferredcites →https://doi.org/10.1074/jbc.m701429200openalex-snapshot
Peroxisomal Proliferator-activated Receptor-α-dependent Inhibition of Endothelial Cell Proliferation and Tumorigenesis
inferredcites →https://doi.org/10.1080/01926230490515283openalex-snapshot
Decreased Longevity and Enhancement of Age-Dependent Lesions in Mice Lacking the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα)
inferredcites →https://doi.org/10.1093/carcin/bgh285openalex-snapshot
Role of peroxisome proliferator-activated receptor- (PPAR ) in bezafibrate-induced hepatocarcinogenesis and cholestasis
inferredcites →https://doi.org/10.1093/carcin/bgi329openalex-snapshot
Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor α to Wy-14,643-induced liver tumorigenesis
inferredcites →https://doi.org/10.1093/toxsci/kfm206openalex-snapshot
The PPARα-Humanized Mouse: A Model to Investigate Species Differences in Liver Toxicity Mediated by PPARα
inferredcites →https://doi.org/10.1096/fj.02-0640fjeopenalex-snapshot
Cytochrome P450 2C9‐derived epoxyeicosatrienoic acids induce angiogenesis via cross‐talk with the epidermal growth factor receptor
inferredcites →https://doi.org/10.1128/mcb.00317-07openalex-snapshot
Peroxisome Proliferator-Activated Receptor α Regulates a MicroRNA-Mediated Signaling Cascade Responsible for Hepatocellular Proliferation
inferredcites →https://doi.org/10.1128/mcb.00605-06openalex-snapshot
Peroxisome Proliferator-Activated Receptor γ Regulates E-Cadherin Expression and Inhibits Growth and Invasion of Prostate Cancer
inferredcites →https://doi.org/10.1136/gut.52.9.1317openalex-snapshot
Potential role for peroxisome proliferator activated receptor (PPAR) in preventing colon cancer
inferredcites →https://doi.org/10.1152/physrev.2001.81.3.1269openalex-snapshot
Nuclear Hormone Receptors and Gene Expression
inferredcites →https://doi.org/10.1155/2008/431763openalex-snapshot
Peroxisome Proliferator‐Activated Receptor‐ γ Ligands: Potential Pharmacological Agents for Targeting the Angiogenesis Signaling Cascade in Cancer
inferredcites →https://doi.org/10.1155/2008/548919openalex-snapshot
PPAR Ligands for Cancer Chemoprevention
inferredcites →https://doi.org/10.1158/0008-5472.can-05-4277openalex-snapshot
Ligand Activation of Peroxisome Proliferator–Activated Receptor β Inhibits Colon Carcinogenesis
inferredcites →https://doi.org/10.1158/1078-0432.ccr-05-2556openalex-snapshot
Peroxisome Proliferator–Activated Receptor α Activation Decreases Metastatic Potential of Melanoma Cells In vitro via Down-Regulation of Akt
inferredcites →https://doi.org/10.1158/1535-7163.mct-06-0722openalex-snapshot
Clofibric acid, a peroxisome proliferator–activated receptor α ligand, inhibits growth of human ovarian cancer
inferredcites →https://doi.org/10.1159/000479571openalex-snapshot
Induction of the Vitamin D Receptor Attenuates Autophagy Dysfunction-Mediated Cell Death Following Traumatic Brain Injury
inferredcites →https://doi.org/10.1161/01.atv.0000151648.58516.ebopenalex-snapshot
Cytochrome P4502C9-Derived Epoxyeicosatrienoic Acids Induce the Expression of Cyclooxygenase-2 in Endothelial Cells
inferredcites →https://doi.org/10.1161/01.res.0000113781.08139.81openalex-snapshot
PPARα Activators Inhibit Vascular Endothelial Growth Factor Receptor-2 Expression by Repressing Sp1-Dependent DNA Binding and Transactivation
inferredcites →https://doi.org/10.1161/circresaha.107.164384openalex-snapshot
Peroxisome Proliferator-Activated Receptor-γ–Mediated Effects in the Vasculature
inferredcites →https://doi.org/10.1172/jci117252openalex-snapshot
Mechanisms of fatty acid-induced inhibition of glucose uptake.
inferredcites →https://doi.org/10.1172/jci22756openalex-snapshot
PPARα inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a
inferredcites →https://doi.org/10.1186/1476-4598-5-13openalex-snapshot
In vitro and in vivo effects of the PPAR-alpha agonists fenofibrate and retinoic acid in endometrial cancer
inferredcites →https://doi.org/10.1210/edrv.20.5.0380openalex-snapshot
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism
inferredcites →https://doi.org/10.1210/endo.137.1.8536636openalex-snapshot
Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
inferredcites →https://doi.org/10.1371/journal.pone.0000260openalex-snapshot
PPARα Deficiency in Inflammatory Cells Suppresses Tumor Growth
inferredcites →https://doi.org/10.1539/joh.49.172openalex-snapshot
Di(2‐ethylhexyl)phthalate Induces Hepatic Tumorigenesis through a Peroxisome Proliferator‐activated Receptor α‐independent Pathway
inferredcites →https://doi.org/10.1539/joh.l7105openalex-snapshot
Different Mechanisms of DEHP‐induced Hepatocellular Adenoma Tumorigenesis in Wild‐type and Pparα‐null Mice
inferredcites →https://doi.org/10.2337/db07-0765openalex-snapshot
Selective Activation of Peroxisome Proliferator–Activated Receptor (PPAR)α and PPARγ Induces Neoangiogenesis Through a Vascular Endothelial Growth Factor–Dependent Mechanism
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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RETRACTED ARTICLE: EET signaling in cancer
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Targeting cytochrome P450-dependent cancer cell mitochondria: cancer associated CYPs and where to find them
inferred← citeshttps://doi.org/10.1016/j.chembiol.2014.05.008openalex-snapshot
Metabolic Profiling Reveals PAFAH1B3 as a Critical Driver of Breast Cancer Pathogenicity
inferred← citeshttps://doi.org/10.1016/j.ebiom.2020.102696openalex-snapshot
Enhanced monoacylglycerol lipolysis by ABHD6 promotes NSCLC pathogenesis
inferred← citeshttps://doi.org/10.1016/j.jfutfo.2026.03.004openalex-snapshot
Cajanstilbenoid A from Pigeon Pea: A Functional Food Component for Managing High-Fat Diet-Induced Hepatic Steatosis via PPARα Activation
inferred← citeshttps://doi.org/10.1016/j.mce.2016.02.005openalex-snapshot
Expression of Peroxisome Proliferator-Activated Receptor alpha (PPARα) in somatotropinomas: Relationship with Aryl hydrocarbon receptor Interacting Protein (AIP) and in vitro effects of fenofibrate in GH3 cells
inferred← citeshttps://doi.org/10.1016/j.taap.2022.116127openalex-snapshot
Dibutylstannanediyl (2Z,2′Z)-bis(4-(benzylamino)-4-oxobut-2-enoate inhibits prostate cancer progression by activating p38 MAPK/PPARα/SMAD4 signaling
inferred← citeshttps://doi.org/10.1039/c8dt03950jopenalex-snapshot
Synthesis and characterization of cyclohexane-1 R ,2 R -diamine-based Pt( iv ) dicarboxylato anticancer prodrugs: their selective activity against human colon cancer cell lines
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Expression of Peroxisome Proliferator-Activated Receptor Alpha (PPARα) in Non-Somatotroph Pituitary Tumours and the Effects of PPARα Agonists on MMQ Cells
inferred← citeshttps://doi.org/10.1074/jbc.m109.081554openalex-snapshot
The Anti-tumorigenic Properties of Peroxisomal Proliferator-activated Receptor α Are Arachidonic Acid Epoxygenase-mediated
inferred← citeshttps://doi.org/10.1093/carcin/bgv032openalex-snapshot
Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death
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The Role of Peroxisome Proliferator-Activated Receptors in the Esophageal, Gastric, and Colorectal Cancer
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Pan-PPAR Agonist, Bezafibrate, Restores Angiogenesis in Hindlimb Ischemia in Normal and Diabetic Rats
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The Emerging Role of PPAR Beta/Delta in Tumor Angiogenesis
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Fenofibrate in cancer: mechanisms involved in anticancer activity
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Factors that Influence Fenofibrate Effects on Cancer Cells
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Aberrant control of NF-κB in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode
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Pleiotropic Functions of Cytochrome P450 Monooxygenase-Derived Eicosanoids in Cancer
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A comparison of peroxisome proliferator-activated receptor-α agonist and antagonist on human umbilical vein endothelial cells angiogenesis
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Role of peroxisome proliferator-activated receptors alpha and gamma in gastric ulcer: An overview of experimental evidences
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