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Bone Effects of Biologic Drugs in Rheumatoid Arthritis

https://doi.org/10.1155/2013/945945
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1529-0131(199810)41:10<1798::aid-art11>3.0.co;2-lopenalex-snapshot
Altered susceptibility to collagen-induced arthritis in transgenic mice with aberrant expression of interleukin-1 receptor antagonist
inferredcites →https://doi.org/10.1002/1529-0131(199812)41:12<2196::aid-art15>3.0.co;2-2openalex-snapshot
Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist
inferredcites →https://doi.org/10.1002/1529-0131(199904)42:3<498::aid-anr15>3.0.co;2-aopenalex-snapshot
Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: Comparison of efficacy in animal models with human clinical data
inferredcites →https://doi.org/10.1002/1529-0131(200002)43:2<250::aid-anr3>3.0.co;2-popenalex-snapshot
Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
inferredcites →https://doi.org/10.1002/acr.20612openalex-snapshot
Changes in hand bone mineral density and the association with the level of disease activity in patients with RA
inferredcites →https://doi.org/10.1002/art.1780310614openalex-snapshot
Interleukin‐6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides
inferredcites →https://doi.org/10.1002/art.21110openalex-snapshot
Prevalence of and risk factors for low bone mineral density and vertebral fractures in patients with systemic lupus erythematosus
inferredcites →https://doi.org/10.1002/art.25053openalex-snapshot
Rapid and sustained improvement in bone and cartilage turnover markers with the anti–interleukin‐6 receptor inhibitor tocilizumab plus methotrexate in rheumatoid arthritis patients with an inadequate response to methotrexate: Results from a substudy of the multicenter double‐blind,…
inferredcites →https://doi.org/10.1002/art.30158openalex-snapshot
Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: Results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structu
inferredcites →https://doi.org/10.1002/j.1460-2075.1991.tb04978.xopenalex-snapshot
Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.
inferredcites →https://doi.org/10.1002/jbmr.1489openalex-snapshot
Effects of disease-modifying antirheumatic drugs on nonvertebral fracture risk in rheumatoid arthritis: A population-based cohort study
inferredcites →https://doi.org/10.1002/jcb.23352openalex-snapshot
T cell‐mediated increased osteoclast formation from peripheral blood as a mechanism for crohn's disease‐associated bone loss
inferredcites →https://doi.org/10.1002/path.2153openalex-snapshot
Lymphocytes and synovial fluid fibroblasts support osteoclastogenesis through RANKL, TNFα, and IL‐7 in an in vitro model derived from human psoriatic arthritis
inferredcites →https://doi.org/10.1007/s00198-012-2113-8openalex-snapshot
Osteoporosis drug therapy strategies in the setting of disease-modifying agents for autoimmune disease
inferredcites →https://doi.org/10.1007/s00774-011-0321-5openalex-snapshot
Role of osteoclasts and interleukin-17 in the pathogenesis of rheumatoid arthritis: crucial ‘human osteoclastology’
inferredcites →https://doi.org/10.1007/s10238-010-0117-2openalex-snapshot
Osteoclastogenesis and arthritis
inferredcites →https://doi.org/10.1016/j.ajpath.2012.03.023openalex-snapshot
Type 1 Interferons Suppress Accelerated Osteoclastogenesis and Prevent Loss of Bone Mass During Systemic Inflammatory Responses to Pneumocystis Lung Infection
inferredcites →https://doi.org/10.1016/j.bone.2004.07.004openalex-snapshot
TNF-α antibodies and osteoprotegerin decrease systemic bone loss associated with inflammation through distinct mechanisms in collagen-induced arthritis
inferredcites →https://doi.org/10.1016/j.jbspin.2010.03.002openalex-snapshot
Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis
inferredcites →https://doi.org/10.1016/j.semarthrit.2012.01.004openalex-snapshot
IL-6 Receptor Inhibition Positively Modulates Bone Balance in Rheumatoid Arthritis Patients with an Inadequate Response to Anti-Tumor Necrosis Factor Therapy: Biochemical Marker Analysis of Bone Metabolism in the Tocilizumab RADIATE Study (NCT00106522)
inferredcites →https://doi.org/10.1016/s0140-6736(94)91049-9openalex-snapshot
Generalised bone loss in patients with early rheumatoid arthritis
inferredcites →https://doi.org/10.1016/s8756-3282(01)00420-3openalex-snapshot
Tumor necrosis factor-α cooperates with receptor activator of nuclear factor κB ligand in generation of osteoclasts in stromal cell-depleted rat bone marrow cell culture
inferredcites →https://doi.org/10.1038/nm1538openalex-snapshot
Dickkopf-1 is a master regulator of joint remodeling
inferredcites →https://doi.org/10.1053/sarh.2001.23704openalex-snapshot
Uncoupling of inflammatory and destructive mechanisms in arthritis
inferredcites →https://doi.org/10.1055/s-2007-978815openalex-snapshot
Effect of 1α,25(OH)2-Vitamin D3on TNFα-Mediated Apoptosis of Human Primary Osteoblast-Like Cellsin Vitro
inferredcites →https://doi.org/10.1074/jbc.m106339200openalex-snapshot
Expression of the Osteoblast Differentiation Factor RUNX2 (Cbfa1/AML3/Pebp2αA) Is Inhibited by Tumor Necrosis Factor-α
inferredcites →https://doi.org/10.1074/jbc.m507804200openalex-snapshot
Transcriptional Regulation of the Osterix (Osx, Sp7) Promoter by Tumor Necrosis Factor Identifies Disparate Effects of Mitogen-activated Protein Kinase and NFκB Pathways
inferredcites →https://doi.org/10.1084/jem.191.2.275openalex-snapshot
Tumor Necrosis Factor α Stimulates Osteoclast Differentiation by a Mechanism Independent of the Odf/Rankl–Rank Interaction
inferredcites →https://doi.org/10.1093/rheumatology/32.5.387openalex-snapshot
BONE METABOLISM IN RHEUMATOID ARTHRITIS; RELATION TO DISEASE ACTIVITY
inferredcites →https://doi.org/10.1093/rheumatology/38.3.202openalex-snapshot
Cytokine production by synovial T cells in rheumatoid arthritis
inferredcites →https://doi.org/10.1093/rheumatology/kei082openalex-snapshot
Increase in bone mineral density of patients with rheumatoid arthritis treated with anti-TNF-α antibody: a prospective open-label pilot study
inferredcites →https://doi.org/10.1093/rheumatology/kei280openalex-snapshot
The effect of infliximab on bone metabolism markers in patients with rheumatoid arthritis
inferredcites →https://doi.org/10.1097/01.bor.0000231913.32364.32openalex-snapshot
Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory bone disease
inferredcites →https://doi.org/10.1136/ard.2003.017780openalex-snapshot
Bone mineral density in patients with rheumatoid arthritis treated with infliximab
inferredcites →https://doi.org/10.1136/ard.2005.044198openalex-snapshot
Evaluation of bone mineral density, bone metabolism, osteoprotegerin and receptor activator of the NFκB ligand serum levels during treatment with infliximab in patients with rheumatoid arthritis
inferredcites →https://doi.org/10.1136/ard.2007.076604openalex-snapshot
Long-term effects of infliximab on bone and cartilage turnover markers in patients with rheumatoid arthritis
inferredcites →https://doi.org/10.1136/ard.2007.086348openalex-snapshot
Changes in hand and generalised bone mineral density in patients with recent-onset rheumatoid arthritis
inferredcites →https://doi.org/10.1136/ard.2008.091611openalex-snapshot
Bone mineral density in rheumatoid arthritis patients 1 year after adalimumab therapy: arrest of bone loss
inferredcites →https://doi.org/10.1136/ard.2008.104786openalex-snapshot
Interleukin-1 is essential for systemic inflammatory bone loss
inferredcites →https://doi.org/10.1136/ard.2008.106484openalex-snapshot
Bone loss in patients with active early rheumatoid arthritis: infliximab and methotrexate compared with methotrexate treatment alone. Explorative analysis from a 12-month randomised, double-blind, placebo-controlled study
inferredcites →https://doi.org/10.1136/ard.2009.127787openalex-snapshot
Stable bone mineral density in lumbar spine and hip in contrast to bone loss in the hands during long-term treatment with infliximab in patients with rheumatoid arthritis
inferredcites →https://doi.org/10.1136/ard.59.suppl_1.i81openalex-snapshot
Arguments for interleukin 1 as a target in chronic arthritis
inferredcites →https://doi.org/10.1136/bmj.306.6877.558openalex-snapshot
Risk of vertebral fracture in women with rheumatoid arthritis.
inferredcites →https://doi.org/10.1155/2011/765624openalex-snapshot
The Roles of Interleukin-6 in the Pathogenesis of Rheumatoid Arthritis
inferredcites →https://doi.org/10.1172/jci11176openalex-snapshot
TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
inferredcites →https://doi.org/10.1172/jci117187openalex-snapshot
Interleukin-1 receptor antagonist decreases bone loss and bone resorption in ovariectomized rats.
inferredcites →https://doi.org/10.1172/jci16069openalex-snapshot
Mechanisms of TNF-α– and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis
inferredcites →https://doi.org/10.1186/1471-2474-12-54openalex-snapshot
Adalimumab reduces hand bone loss in rheumatoid arthritis independent of clinical response: Subanalysis of the PREMIER study
inferredcites →https://doi.org/10.1186/ar1872openalex-snapshot
Imbalance of local bone metabolism in inflammatory arthritis and its reversal upon tumor necrosis factor blockade: direct analysis of bone turnover in murine arthritis
inferredcites →https://doi.org/10.1186/ar2219openalex-snapshot
A 1-year case-control study in patients with rheumatoid arthritis indicates prevention of loss of bone mineral density in both responders and nonresponders to infliximab
inferredcites →https://doi.org/10.1186/ar2277openalex-snapshot
Tumour necrosis factor blockade and the risk of osteoporosis: back to the future
inferredcites →https://doi.org/10.1186/ar2879openalex-snapshot
RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFα or anti-IL-1 therapies
inferredcites →https://doi.org/10.1210/en.143.3.1108openalex-snapshot
TNF Potently Activates Osteoclasts, through a Direct Action Independent of and Strongly Synergistic with RANKL
inferredcites →https://doi.org/10.1210/endo.141.11.7739openalex-snapshot
Inhibition of Osteoblast Differentiation by Tumor Necrosis Factor-α*
inferredcites →https://doi.org/10.1210/endo.143.3.8701openalex-snapshot
TNFα Potently Activates Osteoclasts, through a Direct Action Independent of and Strongly Synergistic with RANKL
inferredcites →https://doi.org/10.1359/jbmr.070207openalex-snapshot
Effect of Blockade of TNF-α and Interleukin-1 Action on Bone Resorption in Early Postmenopausal Women
inferredcites →https://doi.org/10.1677/joe-08-0568openalex-snapshot
Bone loss in inflammatory disorders
inferredcites →https://doi.org/10.4049/jimmunol.1003986openalex-snapshot
IL-23 Is Critical for Induction of Arthritis, Osteoclast Formation, and Maintenance of Bone Mass
inferredcites →https://doi.org/10.4049/jimmunol.148.10.3152openalex-snapshot
Inhibition of tumor necrosis factor (TNF)-mediated NF-kappa B activation by selective blockade of the human 55-kDa TNF receptor
inferredcites →https://doi.org/10.4049/jimmunol.163.9.5049openalex-snapshot
IL-1αβ Blockade Prevents Cartilage and Bone Destruction in Murine Type II Collagen-Induced Arthritis, Whereas TNF-α Blockade Only Ameliorates Joint Inflammation
inferredcites →https://doi.org/10.7326/0003-4819-133-10-200011210-00012openalex-snapshot
The Incidence of Fracture among Patients with Inflammatory Bowel Disease: A Population-Based Cohort Study

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4058421openalex-extracted
Association between Biologic Therapy and Fracture Incidence in Patients with Selected Rheumatic and Autoimmune Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
inferred← citeshttps://doi.org/10.1002/jbmr.2592openalex-snapshot
NF-κB Has a Direct Role in Inhibiting Bmp- and Wnt-Induced Matrix Protein Expression
inferred← citeshttps://doi.org/10.1002/prp2.169openalex-snapshot
Modeling effects of dexamethasone on disease progression of bone mineral density in collagen‐induced arthritic rats
inferred← citeshttps://doi.org/10.1007/978-3-030-46725-8_18openalex-snapshot
Osteoclasts in Cardiovascular Calcification
inferred← citeshttps://doi.org/10.1007/s00264-014-2386-yopenalex-snapshot
Induction of osteoclast progenitors in inflammatory conditions: key to bone destruction in arthritis
inferred← citeshttps://doi.org/10.1007/s10787-021-00815-wopenalex-snapshot
Infliximab prevents systemic bone loss and suppresses tendon inflammation in a collagen-induced arthritis rat model
inferred← citeshttps://doi.org/10.1007/s11926-016-0609-5openalex-snapshot
Infections With Biologics in Rheumatoid Arthritis and Related Conditions: a Scoping Review of Serious or Hospitalized Infections in Observational Studies
inferred← citeshttps://doi.org/10.1007/s12016-025-09046-1openalex-snapshot
Osteoimmunology: Crosstalk Between T Cells and Osteoclasts in Osteoporosis
inferred← citeshttps://doi.org/10.1016/b978-0-12-816992-6.00003-6openalex-snapshot
Anti-inflammatory efficacy of some potentially bioactive natural products against rheumatoid arthritis
inferred← citeshttps://doi.org/10.1016/j.injury.2023.111203openalex-snapshot
Cytokines: The links between bone and the immune system
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Regulatory cells in the skin: Pathophysiologic role and potential targets for anti-inflammatory therapies
inferred← citeshttps://doi.org/10.1016/j.jor.2025.03.032openalex-snapshot
Outcomes and complications of shoulder arthroplasty in patients with rheumatoid arthritis: A large insurance claims matched cohort analysis
inferred← citeshttps://doi.org/10.1016/j.phrs.2022.106278openalex-snapshot
Association between biologic therapy and fracture incidence in patients with selected rheumatic and autoimmune diseases: A systematic review and meta-analysis of randomized controlled trials
inferred← citeshttps://doi.org/10.1038/s41368-019-0068-8openalex-snapshot
Interleukin-1β is a potential therapeutic target for periodontitis: a narrative review
inferred← citeshttps://doi.org/10.1038/s41413-020-00105-1openalex-snapshot
Molecular mechanisms and clinical management of cancer bone metastasis
inferred← citeshttps://doi.org/10.1038/s41598-021-89625-2openalex-snapshot
IL-23 receptor deficiency results in lower bone mass via indirect regulation of bone formation
inferred← citeshttps://doi.org/10.1039/d3bm00544eopenalex-snapshot
Immune homeostasis modulation by hydrogel-guided delivery systems: a tool for accelerated bone regeneration
inferred← citeshttps://doi.org/10.1080/08923973.2020.1745830openalex-snapshot
Cholinergic agonists inhibit proliferation of human fibroblast-like synoviocytes and monocytic cell lines and reduce VEGF and MMPs expression by these cells
inferred← citeshttps://doi.org/10.1080/08952841.2018.1522126openalex-snapshot
Resveratrol restores the level of key inflammatory cytokines and RANKL/OPG ratio in the femur of rat osteoporosis model
inferred← citeshttps://doi.org/10.1097/md.0000000000004669openalex-snapshot
Gout increases risk of fracture
inferred← citeshttps://doi.org/10.1155/2013/875363openalex-snapshot
The Role of TNF‐α and TNF Superfamily Members in the Pathogenesis of Calcific Aortic Valvular Disease
inferred← citeshttps://doi.org/10.1155/2015/782382openalex-snapshot
The Role of IL‐1 β in the Bone Loss during Rheumatic Diseases
inferred← citeshttps://doi.org/10.1186/1476-511x-14-3openalex-snapshot
Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model
inferred← citeshttps://doi.org/10.1186/s13018-019-1317-4openalex-snapshot
Gout is not associated with the risk of fracture: a meta-analysis
inferred← citeshttps://doi.org/10.1186/s13075-020-02242-8openalex-snapshot
High susceptibility to collagen-induced arthritis in mice with progesterone receptors selectively inhibited in osteoprogenitor cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0136116openalex-snapshot
A Short Peptide That Mimics the Binding Domain of TGF-β1 Presents Potent Anti-Inflammatory Activity
inferred← citeshttps://doi.org/10.14393/ufu.di.2014.374openalex-snapshot
Desenvolvimento de peptideo bioativo modulador da resposta immune
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Role of Cytokines in Bone Diseases and Their Therapeutic Application
inferred← citeshttps://doi.org/10.21608/adjalexu.2016.59274openalex-snapshot
EFFECT OF FISH OIL ON ALVEOLAR BONE OF RATS WITH INDUCED RHEUMATOID ARTHRITIS
inferred← citeshttps://doi.org/10.21608/adjalexu.2018.57782openalex-snapshot
PREVALENCE OF THE OCCUPATIONAL HAZARDS AMONG MINISTRY OF HEALTH DENTISTS, ALEXANDRIA, EGYPT
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1925819openalex-snapshot
Osteoimmunology: interactions of the bone and immune system
inferred← citeshttps://doi.org/10.4103/njms.njms_436_21openalex-snapshot
Role of various pharmacologic agents in alveolar bone regeneration: A review
inferred← citeshttps://doi.org/10.4110/in.2018.18.e8openalex-snapshot
Regulation of Osteoclast Differentiation by Cytokine Networks
inferred← citeshttps://doi.org/10.5312/wjo.v6.i1.106openalex-snapshot
Hand bone mass in rheumatoid arthritis: A review of the literature
inferred← citeshttps://doi.org/10.5455/jice.20170218092913openalex-snapshot
Effects of Trichilia monadelpha (Meliaceae) extracts on bone histomorphology in complete Freund's adjuvant-induced arthritis
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