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Indirubin and Indirubin Derivatives for Counteracting Proliferative Diseases

https://doi.org/10.1155/2015/654098

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Comparison of Refined and Crude Indigo Naturalis Ointment in Treating Psoriasis: Randomized, Observer-Blind, Controlled, Intrapatient Trial

inferredcites →https://doi.org/10.1002/cbic.200400108openalex-snapshot

From the Insoluble Dye Indirubin towards Highly Active, Soluble CDK2‐Inhibitors

inferredcites →https://doi.org/10.1002/cmdc.201000374openalex-snapshot

Synthesis and Bioactivity of Carbohydrate Derivatives of Indigo, Its Isomers and Heteroanalogues

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Exploring the Anticancer Activity of Functionalized Isoindigos: Synthesis, Drug‐like Potential, Mode of Action and Effect on Tumor‐Induced Xenografts

inferredcites →https://doi.org/10.1002/ijc.25909openalex-snapshot

Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2‐mediated JAK/STAT3 signaling in endothelial cell

inferredcites →https://doi.org/10.1002/jcb.23055openalex-snapshot

Indirubin‐3'‐monoxime, a derivative of a chinese antileukemia medicine, inhibits angiogenesis

inferredcites →https://doi.org/10.1002/jemt.20832openalex-snapshot

Effect of indirubin‐3‐monoxime against lung cancer as evaluated by histological and transmission electron microscopic studies

inferredcites →https://doi.org/10.1002/jps.23696openalex-snapshot

Enhancement of Oral Bioavailability of E804 by Self-Nanoemulsifying Drug Delivery System (SNEDDS) in Rats

inferredcites →https://doi.org/10.1002/mc.20761openalex-snapshot

5′‐Nitro‐indirubinoxime inhibits epidermal growth factor‐ and phorbol ester‐induced AP‐1 activity and cell transformation through inhibition of phosphorylation of Pin1

inferredcites →https://doi.org/10.1002/mc.22307openalex-snapshot

5-diphenylacetamido-indirubin-3′-oxime as a novel mitochondria-targeting agent with anti-leukemic activities

inferredcites →https://doi.org/10.1007/978-3-030-12858-6openalex-snapshot

Progress in the Chemistry of Organic Natural Products 109

inferredcites →https://doi.org/10.1007/978-3-319-04900-7_2openalex-snapshot

A Colorful History: The Evolution of Indigoids

inferredcites →https://doi.org/10.1007/s00432-004-0579-2openalex-snapshot

Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules with their origin in traditional Chinese phytomedicine

inferredcites →https://doi.org/10.1007/s10456-010-9181-1openalex-snapshot

Anti-angiogenic potential of small molecular inhibitors of cyclin dependent kinases in vitro

inferredcites →https://doi.org/10.1007/s10495-009-0315-0openalex-snapshot

NFκB signaling in carcinogenesis and as a potential molecular target for cancer therapy

inferredcites →https://doi.org/10.1016/0006-2952(96)00098-6openalex-snapshot

Induction of differentiation and down-regulation of c-myb gene expression in ML-1 human myeloblastic leukemia cells by the clinically effective anti-leukemia agent meisoindigo

inferredcites →https://doi.org/10.1016/0165-7992(92)90099-4openalex-snapshot

The presence of genotoxic and bioactive components in indigo dyed fabrics — a possible heatlh risk?

inferredcites →https://doi.org/10.1016/j.atherosclerosis.2010.01.040openalex-snapshot

5′-Nitro-indirubinoxime inhibits inflammatory response in TNF-α stimulated human umbilical vein endothelial cells

inferredcites →https://doi.org/10.1016/j.bbagen.2009.11.007openalex-snapshot

5′-Nitro-indirubinoxime induces G1 cell cycle arrest and apoptosis in salivary gland adenocarcinoma cells through the inhibition of Notch-1 signaling

inferredcites →https://doi.org/10.1016/j.bcp.2008.01.021openalex-snapshot

Critical role of Bid and Bax in indirubin-3′-monoxime-induced apoptosis in human cancer cells

inferredcites →https://doi.org/10.1016/j.bcp.2010.09.010openalex-snapshot

Sensitization of melanoma cells for death ligand-induced apoptosis by an indirubin derivative—Enhancement of both extrinsic and intrinsic apoptosis pathways

inferredcites →https://doi.org/10.1016/j.bcp.2011.12.003openalex-snapshot

An indirubin derivative, E804, exhibits potent angiosuppressive activity

inferredcites →https://doi.org/10.1016/j.bcp.2014.07.009openalex-snapshot

The pleiotropic profile of the indirubin derivative 6BIO overcomes TRAIL resistance in cancer

inferredcites →https://doi.org/10.1016/j.biotechadv.2015.08.001openalex-snapshot

Discovery and resupply of pharmacologically active plant-derived natural products: A review

inferredcites →https://doi.org/10.1016/j.bmc.2010.04.066openalex-snapshot

Synthesis and cytotoxicity of novel indirubin-5-carboxamides

inferredcites →https://doi.org/10.1016/j.bmc.2013.11.031openalex-snapshot

7,7′-Diazaindirubin—A small molecule inhibitor of casein kinase 2 in vitro and in cells

inferredcites →https://doi.org/10.1016/j.bmcl.2005.05.105openalex-snapshot

Induction of apoptosis by a novel indirubin-5-nitro-3′-monoxime, a CDK inhibitor, in human lung cancer cells

inferredcites →https://doi.org/10.1016/j.bmcl.2011.07.011openalex-snapshot

Synthesis of methoxy- and bromo-substituted indirubins and their activities on apoptosis induction in human neuroblastoma cells

inferredcites →https://doi.org/10.1016/j.canlet.2008.02.013openalex-snapshot

Indirubin-3′-monoxime, a derivative of a Chinese anti-leukemia medicine, inhibits Notch1 signaling

inferredcites →https://doi.org/10.1016/j.canlet.2008.08.033openalex-snapshot

5′-nitro-indirubinoxime induces G2/M cell cycle arrest and apoptosis in human KB oral carcinoma cells

inferredcites →https://doi.org/10.1016/j.canlet.2011.03.006openalex-snapshot

5′-Nitro-indirubinoxime, an indirubin derivative, suppresses metastatic ability of human head and neck cancer cells through the inhibition of Integrin β1/FAK/Akt signaling

inferredcites →https://doi.org/10.1016/j.canlet.2011.10.029openalex-snapshot

Inhibition of Plk1 and Pin1 by 5′-nitro-indirubinoxime suppresses human lung cancer cells

inferredcites →https://doi.org/10.1016/j.chembiol.2003.11.010openalex-snapshot

GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins

inferredcites →https://doi.org/10.1016/j.ejphar.2011.07.047openalex-snapshot

A novel indirubin derivative PHII-7 potentiates adriamycin cytotoxicity via inhibiting P-glycoprotein expression in human breast cancer MCF-7/ADR cells

inferredcites →https://doi.org/10.1016/j.jdermsci.2009.02.007openalex-snapshot

Anti-psoriatic effects of indigo naturalis on the proliferation and differentiation of keratinocytes with indirubin as the active component

inferredcites →https://doi.org/10.1016/j.jdermsci.2012.05.008openalex-snapshot

Indirubin, an acting component of indigo naturalis, inhibits EGFR activation and EGF-induced CDC25B gene expression in epidermal keratinocytes

inferredcites →https://doi.org/10.1016/j.jep.2010.05.016openalex-snapshot

Indirubin shows anti-angiogenic activity in an in vivo zebrafish model and an in vitro HUVEC model

inferredcites →https://doi.org/10.1016/j.jep.2012.11.044openalex-snapshot

Indigo naturalis upregulates claudin-1 expression in human keratinocytes and psoriatic lesions

inferredcites →https://doi.org/10.1016/j.jmb.2003.08.031openalex-snapshot

Structural Characterization of the GSK-3β Active Site Using Selective and Non-selective ATP-mimetic Inhibitors

inferredcites →https://doi.org/10.1016/j.leukres.2009.09.001openalex-snapshot

Imatinib achieved complete cytogenetic response in a CML patient received 32-year indirubin and its derivative treatment

inferredcites →https://doi.org/10.1016/j.leukres.2012.12.017openalex-snapshot

5′-OH-5-nitro-Indirubin oxime (AGM130), an Indirubin derivative, induces apoptosis of Imatinib-resistant chronic myeloid leukemia cells

inferredcites →https://doi.org/10.1016/j.molonc.2012.02.002openalex-snapshot

Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling

inferredcites →https://doi.org/10.1016/j.molonc.2012.10.013openalex-snapshot

Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively‐activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells

inferredcites →https://doi.org/10.1016/j.phymed.2014.02.013openalex-snapshot

Efficacy and safety of Indigo naturalis extract in oil (Lindioil) in treating nail psoriasis: A randomized, observer-blind, vehicle-controlled trial

inferredcites →https://doi.org/10.1016/j.vph.2014.10.005openalex-snapshot

Antiplatelet action of indirubin-3′-monoxime through suppression of glycoprotein VI-mediated signal transduction: A possible role for ERK signaling in platelets

inferredcites →https://doi.org/10.1016/s0065-230x(08)60862-3openalex-snapshot

How Tumors Become Angiogenic

inferredcites →https://doi.org/10.1016/s0092-8674(00)80108-7openalex-snapshot

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

inferredcites →https://doi.org/10.1016/s0092-8674(00)81683-9openalex-snapshot

The Hallmarks of Cancer

inferredcites →https://doi.org/10.1016/s0093-7754(02)70065-1openalex-snapshot

Role of angiogenesis in tumor growth and metastasis

inferredcites →https://doi.org/10.1021/jm031016dopenalex-snapshot

Structural Basis for the Synthesis of Indirubins as Potent and Selective Inhibitors of Glycogen Synthase Kinase-3 and Cyclin-Dependent Kinases

inferredcites →https://doi.org/10.1021/jm060314iopenalex-snapshot

3‘-Substituted 7-Halogenoindirubins, a New Class of Cell Death Inducing Agents

inferredcites →https://doi.org/10.1021/jm800648yopenalex-snapshot

Soluble 3′,6-Substituted Indirubins with Enhanced Selectivity toward Glycogen Synthase Kinase -3 Alter Circadian Period

inferredcites →https://doi.org/10.1021/ml300207aopenalex-snapshot

Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases

inferredcites →https://doi.org/10.1021/np200391copenalex-snapshot

The Relevance of Higher Plants in Lead Compound Discovery Programs

inferredcites →https://doi.org/10.1021/np200906sopenalex-snapshot

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

inferredcites →https://doi.org/10.1021/np9003905openalex-snapshot

Synthesis and Antiproliferative Activity of 7-Azaindirubin-3′-oxime, a 7-Aza Isostere of the Natural Indirubin Pharmacophore

inferredcites →https://doi.org/10.1038/35025220openalex-snapshot

Angiogenesis in cancer and other diseases

inferredcites →https://doi.org/10.1038/374131a0openalex-snapshot

Principles of CDK regulation

inferredcites →https://doi.org/10.1038/9035openalex-snapshot

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

inferredcites →https://doi.org/10.1038/bjc.2015.16openalex-snapshot

Cell migration in paediatric glioma; characterisation and potential therapeutic targeting

inferredcites →https://doi.org/10.1038/jid.2013.92openalex-snapshot

Malassezia Yeasts Produce a Collection of Exceptionally Potent Activators of the Ah (Dioxin) Receptor Detected in Diseased Human Skin

inferredcites →https://doi.org/10.1038/nature05663openalex-snapshot

Pathogenesis and therapy of psoriasis

inferredcites →https://doi.org/10.1038/ni.2060openalex-snapshot

Inflammation meets cancer, with NF-κB as the matchmaker

inferredcites →https://doi.org/10.1038/nrc3599openalex-snapshot

Cancer drug resistance: an evolving paradigm

inferredcites →https://doi.org/10.1038/sj.onc.1204503openalex-snapshot

Anti-mitotic properties of indirubin-3′-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest

inferredcites →https://doi.org/10.1038/sj.onc.1207535openalex-snapshot

Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins

inferredcites →https://doi.org/10.1038/sj.onc.1208012openalex-snapshot

Cyclin-dependent kinase inhibitor indirubin-3′-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies

inferredcites →https://doi.org/10.1038/sj.onc.1210473openalex-snapshot

Indirubin-3′-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK

inferredcites →https://doi.org/10.1046/j.1365-2230.2001.00832.xopenalex-snapshot

Psoriasis − epidemiology and clinical spectrum

inferredcites →https://doi.org/10.1053/euhj.2000.2153openalex-snapshot

Coronary in-stent restenosis—predictors, treatment and prevention

inferredcites →https://doi.org/10.1053/sonc.2002.37263openalex-snapshot

Role of angiogenesis in tumor growth and metastasis

inferredcites →https://doi.org/10.1054/bjoc.2000.1546openalex-snapshot

Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells

inferredcites →https://doi.org/10.1055/s-0032-1315261openalex-snapshot

From Tyrian Purple to Kinase Modulators: Naturally Halogenated Indirubins and Synthetic Analogues

inferredcites →https://doi.org/10.1056/nejmra0804595openalex-snapshot

Psoriasis

inferredcites →https://doi.org/10.1073/pnas.0409467102openalex-snapshot

Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells

inferredcites →https://doi.org/10.1073/pnas.0712365105openalex-snapshot

Dissection of mechanisms of Chinese medicinal formula Realgar- Indigo naturalis as an effective treatment for promyelocytic leukemia

inferredcites →https://doi.org/10.1074/jbc.c100238200openalex-snapshot

Indirubin and Indigo Are Potent Aryl Hydrocarbon Receptor Ligands Present in Human Urine

inferredcites →https://doi.org/10.1074/jbc.m002466200openalex-snapshot

Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease

inferredcites →https://doi.org/10.1074/jbc.m602627200openalex-snapshot

Indirubin Enhances Tumor Necrosis Factor-induced Apoptosis through Modulation of Nuclear Factor-κB Signaling Pathway

inferredcites →https://doi.org/10.1080/1042819021000006295openalex-snapshot

Indirubin and Meisoindigo in the Treatment of Chronic Myelogenous Leukemia in China

inferredcites →https://doi.org/10.1093/cvr/cvt339openalex-snapshot

Indirubin-3′-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migration

inferredcites →https://doi.org/10.1111/j.1432-1033.2004.04173.xopenalex-snapshot

Binding of the potential antitumour agent indirubin‐5‐sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b

inferredcites →https://doi.org/10.1111/j.1600-0447.1954.tb05659.xopenalex-snapshot

PATHOGENESIS AND THERAPY

inferredcites →https://doi.org/10.1124/pr.114.009001openalex-snapshot

The Aryl Hydrocarbon Receptor in Barrier Organ Physiology, Immunology, and Toxicology

inferredcites →https://doi.org/10.1126/science.277.5332.1630openalex-snapshot

STATs and Gene Regulation

inferredcites →https://doi.org/10.1158/0008-5472.can-07-3126openalex-snapshot

Automated, Quantitative Screening Assay for Antiangiogenic Compounds Using Transgenic Zebrafish

inferredcites →https://doi.org/10.1158/0008-5472.can-10-3026openalex-snapshot

Indirubins Decrease Glioma Invasion by Blocking Migratory Phenotypes in Both the Tumor and Stromal Endothelial Cell Compartments

inferredcites →https://doi.org/10.1158/0008-5472.can-10-3852openalex-snapshot

6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells

inferredcites →https://doi.org/10.1158/0008-5472.can-12-4358openalex-snapshot

Indirubin Derivative 6BIO Suppresses Metastasis

inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-1154openalex-snapshot

Antitumor Activity of Novel Indirubin Derivatives in Rat Tumor Model

inferredcites →https://doi.org/10.1158/1078-0432.ccr-11-0431openalex-snapshot

Natura-Alpha Targets Forkhead Box M1 and Inhibits Androgen-Dependent and -Independent Prostate Cancer Growth and Invasion

inferredcites →https://doi.org/10.1161/atvbaha.110.212654openalex-snapshot

Indirubin-3′-Monoxime Blocks Vascular Smooth Muscle Cell Proliferation by Inhibition of Signal Transducer and Activator of Transcription 3 Signaling and Reduces Neointima Formation In Vivo

inferredcites →https://doi.org/10.1161/circinterventions.110.959882openalex-snapshot

Restenosis

inferredcites →https://doi.org/10.1182/blood-2008-05-156422openalex-snapshot

Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML

inferredcites →https://doi.org/10.1186/1471-2407-12-164openalex-snapshot

Indirubin derivative E804 inhibits angiogenesis

inferredcites →https://doi.org/10.1186/1476-4598-9-153openalex-snapshot

A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention

inferredcites →https://doi.org/10.1246/bcsj.69.1621openalex-snapshot

The Synthesis, Antileukemic Activity, and Crystal Structures of Indirubin Derivatives

inferredcites →https://doi.org/10.1371/journal.pone.0070198openalex-snapshot

An Indirubin Derivative, Indirubin-3′-Monoxime Suppresses Oral Cancer Tumorigenesis through the Downregulation of Survivin

inferredcites →https://doi.org/10.1517/13543776.2015.1019865openalex-snapshot

Indirubin derivatives: a patent review (2010 – present)

inferredcites →https://doi.org/10.2147/ijn.s28761openalex-snapshot

Improved oral bioavailability of poorly water-soluble indirubin by a supersaturatable self-microemulsifying drug delivery system

inferredcites →https://doi.org/10.2174/138920307781369409openalex-snapshot

Structure-Based Approaches in the Design of GSK-3 Selective Inhibitors

inferredcites →https://doi.org/10.2174/1566524023362456openalex-snapshot

The Role of STATs in Apoptosis

inferredcites →https://doi.org/10.2174/1871520614666140825112924openalex-snapshot

New Perspective on the Dual Functions of Indirubins in Cancer Therapy and Neuroprotection

inferredcites →https://doi.org/10.3892/or.2012.2094openalex-snapshot

Indirubin-3′-oxime induces mitochondrial dysfunction and triggers growth inhibition and cell cycle arrest in human neuroblastoma cells

inferredcites →https://doi.org/10.3892/or.2013.2334openalex-snapshot

Indirubin-3′-monoxime promotes autophagic and apoptotic death in JM1 human acute lymphoblastic leukemia cells and K562 human chronic myelogenous leukemia cells

inferredcites →https://doi.org/10.4049/jimmunol.0901080openalex-snapshot

Cutting Edge: Necrosis Activates the NLRP3 Inflammasome

inferredcites →https://doi.org/10.4161/cbt.21781openalex-snapshot

A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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6BIO Enhances Oligonucleotide Activity in Cells: A Potential Combinatorial Anti-androgen Receptor Therapy in Prostate Cancer Cells

inferred← citeshttps://doi.org/10.1021/acs.orglett.4c04539openalex-snapshot

Domino Synthesis of Thioindirubin via Aldol Condensation/C–S Cross-Coupling/Cyclization Reaction Using Xanthate as a Sulfur Surrogate

inferred← citeshttps://doi.org/10.1021/acscatal.9b02613openalex-snapshot

Elucidating Cysteine-Assisted Synthesis of Indirubin by a Flavin-Containing Monooxygenase

inferred← citeshttps://doi.org/10.1038/s41598-019-48533-2openalex-snapshot

Mapping insoluble indole metabolites in the gastrointestinal environment of a murine colorectal cancer model using desorption/ionisation on porous silicon imaging

inferred← citeshttps://doi.org/10.1039/bk9781837672301-00045openalex-snapshot

The molecules of colour. New structural derivatives from indigo: tryptanthrin and indirubin

inferred← citeshttps://doi.org/10.1039/d1cb00063bopenalex-snapshot

Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine

inferred← citeshttps://doi.org/10.1039/d2ra01035fopenalex-snapshot

Synthesis and antibacterial activity studies in vitro of indirubin-3′-monoximes

inferred← citeshttps://doi.org/10.1080/00498254.2023.2297745openalex-snapshot

Indirubin mediates adverse intestinal reactions in guinea pigs by downregulating the expression of AchE through AhR

inferred← citeshttps://doi.org/10.1080/07391102.2019.1591301openalex-snapshot

Binding and stability of indirubin-3-monoxime in the GSK3β enzyme: a molecular dynamics simulation and binding free energy study

inferred← citeshttps://doi.org/10.1080/07391102.2023.2294182openalex-snapshot

Theoretical characterization and biological activity investigation of indirubins, cyclin dependent kinases inhibitors

inferred← citeshttps://doi.org/10.1080/13880209.2016.1238949openalex-snapshot

Meisoindigo, but not its core chemical structure indirubin, inhibits zebrafish interstitial leukocyte chemotactic migration

inferred← citeshttps://doi.org/10.1080/13880209.2017.1354387openalex-snapshot

Effects of indirubin and isatin on cell viability, mutagenicity, genotoxicity and BAX/ERCC1 gene expression

inferred← citeshttps://doi.org/10.1111/bjd.16074openalex-snapshot

Indirubin: a novel topical agent in the treatment of psoriasis

inferred← citeshttps://doi.org/10.1111/cbdd.13792openalex-snapshot

Synthesis and activity of novel indirubin derivatives

inferred← citeshttps://doi.org/10.1117/12.3002527openalex-snapshot

Metabolic imaging with FLIM/PLIM indirubin derivatives: an ultrafast window into cellular metabolism and oxygen consumption

inferred← citeshttps://doi.org/10.1134/s0036024424701759openalex-snapshot

In Silico Studies of 2-((2-Hydroxybenzylidene)hydrazineylidene)-2-phenylacetaldehyde Oxime

inferred← citeshttps://doi.org/10.1134/s1070363224110185openalex-snapshot

Design, Synthesis, and Anticancer Activity Evaluation of Novel Betulin Derivatives

inferred← citeshttps://doi.org/10.1155/2017/3082805openalex-snapshot

Indirubin Treatment of Lipopolysaccharide-Induced Mastitis in a Mouse Model and Activity in Mouse Mammary Epithelial Cells

inferred← citeshttps://doi.org/10.1186/s12864-026-12543-yopenalex-snapshot

The pan-plastome of Strobilanthes cusia provided new information about the genetic diversity and cultivation history of an important medicinal and natural dye plant

inferred← citeshttps://doi.org/10.18632/oncotarget.17560openalex-snapshot

Indirubin improves antioxidant and anti-inflammatory functions in lipopolysaccharide-challenged mice

inferred← citeshttps://doi.org/10.2152/jmi.67.158openalex-snapshot

Treatment with indigo plant (Polygonum tinctorium Lour) improves serum lipid profiles in Wistar rats fed a high-fat diet

inferred← citeshttps://doi.org/10.2174/0113895575407443250919042610openalex-snapshot

Synthesis and Biological Properties of Isatin-indole Hybrids: A Review

inferred← citeshttps://doi.org/10.2174/0929867323666160321121819openalex-snapshot

Anti-Psoriasis Agents from Natural Plant Sources

inferred← citeshttps://doi.org/10.25004/ijpsdr.2023.150506openalex-snapshot

Synthesis of Some Quinoline Oximes by an Efficient Method and their Biological Screening

inferred← citeshttps://doi.org/10.26502/fjppr.073openalex-snapshot

Further Investigation of the Potential Anti-neoplastic, Anti-inflammatory and Immunomodulatory Actions of Phenoxybenzamine Using the Broad Institute CLUE Platform

inferred← citeshttps://doi.org/10.29303/jk.v12i4.4569openalex-snapshot

The Effect Of Indigofera Tinctoria Extract On Cdk5 Expression And Signs Of Inflammation In A Chronic Pain Rat Model

inferred← citeshttps://doi.org/10.31018/jans.v13i3.2717openalex-snapshot

A review on the important phytochemicals and their role in psoriasis

inferred← citeshttps://doi.org/10.31989/ffhd.v7i8.376openalex-snapshot

Natural product inhibitors of acetyl-lysine erasers in the prevention and treatment of heart failure

inferred← citeshttps://doi.org/10.3389/fphar.2020.00032openalex-snapshot

Evaluation of the Developmental Toxicity Induced by E804 in Zebrafish Embryos

inferred← citeshttps://doi.org/10.3389/fphar.2022.1014508openalex-snapshot

New insights into the characteristics of DRAK2 and its role in apoptosis: From molecular mechanisms to clinically applied potential

inferred← citeshttps://doi.org/10.3389/fphar.2025.1595019openalex-snapshot

Efficacy of indigo naturalis nanofibrous patches in the treatment of chronic plaque psoriasis: a 4-week prospective, randomized, semi-compartmental paired, positive drug-controlled trial

inferred← citeshttps://doi.org/10.3390/antiox10101514openalex-snapshot

Crucial Role of Reactive Oxygen Species (ROS) for the Proapoptotic Effects of Indirubin Derivatives in Cutaneous SCC Cells

inferred← citeshttps://doi.org/10.3390/antiox8100423openalex-snapshot

p53-Mediated Oxidative Stress Enhances Indirubin-3′-Monoxime-Induced Apoptosis in HCT116 Colon Cancer Cells by Upregulating Death Receptor 5 and TNF-Related Apoptosis-Inducing Ligand Expression

inferred← citeshttps://doi.org/10.3390/app112411599openalex-snapshot

Anti-Psoriatic Effects and IL-22 Targeting Mechanism of Indirubin by Suppressing Keratinocyte Inflammation and Proliferation

inferred← citeshttps://doi.org/10.3390/biom11060777openalex-snapshot

Oximes: Novel Therapeutics with Anticancer and Anti-Inflammatory Potential

inferred← citeshttps://doi.org/10.3390/cancers13081770openalex-snapshot

Small Molecules in the Treatment of Squamous Cell Carcinomas: Focus on Indirubins

inferred← citeshttps://doi.org/10.3390/cells9061451openalex-snapshot

Targeting the JAK/STAT Signaling Pathway Using Phytocompounds for Cancer Prevention and Therapy

inferred← citeshttps://doi.org/10.3390/ijms20051158openalex-snapshot

Key Role of Reactive Oxygen Species (ROS) in Indirubin Derivative-Induced Cell Death in Cutaneous T-Cell Lymphoma Cells

inferred← citeshttps://doi.org/10.3390/molecules22091546openalex-snapshot

Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC

inferred← citeshttps://doi.org/10.3390/ph19050782openalex-snapshot

Traditional Chinese Medicine-Derived Active Ingredient and Formulation Therapy for Glioma: Multi-Target Mechanisms, Drug Delivery Systems, and Advances in Clinical Translational Research

inferred← citeshttps://doi.org/10.3390/pharmaceutics15122728openalex-snapshot

Podophyllotoxin: Recent Advances in the Development of Hybridization Strategies to Enhance Its Antitumoral Profile

inferred← citeshttps://doi.org/10.3892/ijo.2020.5144openalex-snapshot

Isatin inhibits the invasion and metastasis of SH‑SY5Y neuroblastoma cells in vitro and in vivo

inferred← citeshttps://doi.org/10.3987/com-19-14118openalex-snapshot

Syntheses of Indirubins by Aldol Condensation of Isatins with Indoxyl Anion Generated in situ by Lipase-Catalyzed Deacetylation of Indoxyl Acetate

inferred← citeshttps://doi.org/10.4062/biomolther.2018.091openalex-snapshot

Discovery of an Indirubin Derivative as a Novel c-Met Kinase Inhibitor with In Vitro Anti-Tumor Effects

inferred← citeshttps://doi.org/10.4155/ppa-2021-0022openalex-snapshot

Patent Highlights June–July 2021

inferred← citeshttps://doi.org/10.4236/jbm.2018.65015openalex-snapshot

Effect of N’-Acetylindirubin on Proliferation, Apoptosis and Cell Cycle in Acute Myeloid Leukemia HL-60 Cells

inferred← citeshttps://doi.org/10.55730/1300-0527.3681openalex-snapshot

New imidazolidindionedioximes and their Pt(II) complexes: Synthesis and investigation of their antitumoral activities on breast cancer cells

inferred← citeshttps://doi.org/10.70675/1945db5dz72d5z45efzb303z598eb41c6048openalex-snapshot

Human limbal stem cell regulation : importance of Wnt signaling pathway

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