On the public citation graph

Analytical Quality by Design: A Tool for Regulatory Flexibility and Robust Analytics

https://doi.org/10.1155/2015/868727
0 signed · 303 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jps.22325openalex-snapshot
Development of Quality-By-Design Analytical Methods
inferredcites →https://doi.org/10.1007/s00216-012-6302-2openalex-snapshot
Application of quality by design to the development of analytical separation methods
inferredcites →https://doi.org/10.1016/j.chroma.2010.02.001openalex-snapshot
Aspects of the “Design Space” in high pressure liquid chromatography method development
inferredcites →https://doi.org/10.1016/j.chroma.2011.12.041openalex-snapshot
Quality by Design: Multidimensional exploration of the design space in high performance liquid chromatography method development for better robustness before validation
inferredcites →https://doi.org/10.1016/j.jpba.2011.04.015openalex-snapshot
Expanding the term “Design Space” in high performance liquid chromatography (I)
inferredcites →https://doi.org/10.1016/s0263-8762(97)71569-7openalex-snapshot
Organic Process Research and Development
inferredcites →https://doi.org/10.1021/op300292aopenalex-snapshot
Applying QbD Principles To Develop a Generic UHPLC Method Which Facilitates Continual Improvement and Innovation Throughout the Product Lifecycle for a Commercial API
inferredcites →https://doi.org/10.1080/10826076.2013.765457openalex-snapshot
REVERSED-PHASE LIQUID CHROMATOGRAPHIC METHOD DEVELOPMENT IN AN ANALYTICAL QUALITY BY DESIGN FRAMEWORK
inferredcites →https://doi.org/10.1093/chrsci/49.6.439openalex-snapshot
Quality by Design (QbD) Based Development of a Stability Indicating HPLC Method for Drug and Impurities
inferredcites →https://doi.org/10.1155/2013/676501openalex-snapshot
Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Propafenone Hydrochloride in Tablet Dosage Form
inferredcites →https://doi.org/10.1155/2013/738397openalex-snapshot
Quality by Design Approach for the Development and Validation of Glipizide, an Antidiabetic Drug, by RP-UPLC with Application to Formulated Forms and Urine
inferredcites →https://doi.org/10.2533/chimia.2010.825openalex-snapshot
Enhancing the Quality and Efficiency of Analytical Method Development as Part of the Quality by Design Framework
inferredcites →https://doi.org/10.4000/ebc.9418openalex-snapshot
Aspects of the Novel, or E.M. Forster’s (In)formal Criticism
inferredcites →https://doi.org/10.4103/0975-1483.76415openalex-snapshot
Six Sigma: Process of Understanding the Control and Capability of Ranitidine Hydrochloride Tablet
inferredcites →https://doi.org/10.5402/2012/592849openalex-snapshot
Implementation of Quality by Design for the Development and Validation of Pioglitazone Hydrochloride by RP-UPLC with Application to Formulated Forms

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4160588openalex-extracted
Application of Design Space and Quality by Design Methodologies Combined with Ultra High-Performance Liquid Chromatography for the Optimization of the Sample Preparation of Complex Pharmaceutical Dosage Forms
inferred← citeshttps://doi.org/10.2139/ssrn.4490093openalex-extracted
Factorial Design Assisted Rp-Hplc Method for Sımultaneous Estimatıon of Luliconazole and Salicylic Acid: Analytical Quality by Design (AQbD) Approach in Method Development
inferred← citeshttps://doi.org/10.3897/pharmacia.72.e168287zenodo-depositor-declared
Ion-pair RP-HPLC strategy for resolving polarity-mismatched APIs in sustained-release capsules: an AQbD-driven mechanistic and statistical optimization
inferred← citeshttps://doi.org/10.1002/9781118895238.ch10openalex-snapshot
Analytical Method Design, Development, and Lifecycle Management
inferred← citeshttps://doi.org/10.1002/9783527837489.ch4-5openalex-snapshot
Systematic Method Development with an Analytical Quality‐by‐Design Approach Supported by Fusion QbD and UPLC – MS
inferred← citeshttps://doi.org/10.1002/bmc.3859openalex-snapshot
Hazards in chromatographic bioanalysis method development and applications
inferred← citeshttps://doi.org/10.1002/bmc.4169openalex-snapshot
Development of a validated liquid chromatographic method for quantification of sorafenib tosylate in the presence of stress‐induced degradation products and in biological matrix employing analytical quality by design approach
inferred← citeshttps://doi.org/10.1002/bmc.70031openalex-snapshot
Navigating the AQbD Landscape: Enhancing Quality Management in Liquid Chromatography Method Development
inferred← citeshttps://doi.org/10.1002/bmc.70563openalex-snapshot
AQbD‐Based Development and Optimization of a Stability‐Indicating RP‐HPLC Method for Imeglimin With Integration of Lean Six Sigma Principles
inferred← citeshttps://doi.org/10.1002/bmc.70617openalex-snapshot
Challenge‐Oriented Decision Tree for Analytical Method Selection in Metformin, Sodium–Glucose Cotransporter‐2 (SGLT2) Inhibitors and Dipeptidyl Peptidase‐4 (DPP‐4) Inhibitors Triple Antidiabetic Fixed‐Dose Combinations in Pharmaceutical Dosage Forms
inferred← citeshttps://doi.org/10.1002/elps.201600519openalex-snapshot
Establishment and validation of a microfluidic capillary gel electrophoresis platform method for purity analysis of therapeutic monoclonal antibodies
inferred← citeshttps://doi.org/10.1002/elps.201900068openalex-snapshot
Implementation of at‐line capillary zone electrophoresis for fast and reliable determination of adenovirus concentrations in vaccine manufacturing
inferred← citeshttps://doi.org/10.1002/elps.202100157openalex-snapshot
DoE‐based validation of a HPLC–UV method for quantification of rotigotine nanocrystals: Application to in vitro dissolution and ex vivo nasal permeation studies
inferred← citeshttps://doi.org/10.1002/elps.202200072openalex-snapshot
Design of experiment techniques for the optimization of chromatographic analysis conditions: A review
inferred← citeshttps://doi.org/10.1002/elps.8110openalex-snapshot
A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development
inferred← citeshttps://doi.org/10.1002/jms.4789openalex-snapshot
Design of experiment‐based LC‐MS/MS method development for simultaneous estimation of nateglinide and metformin hydrochloride in rat plasma
inferred← citeshttps://doi.org/10.1002/jssc.202100388openalex-snapshot
Implementation of design of experiments for optimization of forced degradation conditions and development of a stability‐indicating high‐performance liquid chromatography method for sepiwhite
inferred← citeshttps://doi.org/10.1002/slct.201803254openalex-snapshot
Modulated Preparation of Capillary Monolithic HILIC Column by Target‐Analogues of Matrine and Oxymatrine and Applied for Extracted Analysis of Sophorae flavescentis radix
inferred← citeshttps://doi.org/10.1002/sscp.202000028openalex-snapshot
Implementation of analytical quality‐by‐design and green analytical chemistry approaches for the development of robust and ecofriendly UHPLC analytical method for quantification of chrysin
inferred← citeshttps://doi.org/10.1002/sscp.202200138openalex-snapshot
Estimation of rutin‐loaded chitosan sodium alginate nanoparticles in rat plasma using a chemometrics‐assisted bioanalytical high‐performance liquid chromatography method
inferred← citeshttps://doi.org/10.1002/sscp.70016openalex-snapshot
A Stability Indicating HPLC Methodology Applying Quality by Design for the Concurrent Estimation of Luliconazole and Clobetasol Propionate in Cream Formulation
inferred← citeshttps://doi.org/10.1002/sscp.70155openalex-snapshot
A Validated Ion‐Pair Reversed‐Phase High‐Performance Liquid Chromatography for Simultaneous Quantification of Metformin Hydrochloride, Empagliflozin, and Linagliptin in the Antidiabetic Drug Combination and Dissolution Media
inferred← citeshttps://doi.org/10.1002/sscp.70225openalex-snapshot
Quality by Design Guided Stability‐Indicating HPLC Method for Concurrent Analysis of Clotrimazole and Mometasone Furoate in Cream Formulation
inferred← citeshttps://doi.org/10.1007/978-981-16-5180-9_19openalex-snapshot
Computers in Pharmaceutical Analysis
inferred← citeshttps://doi.org/10.1007/978-981-33-6897-2_7openalex-snapshot
Green in Analytical Chemistry
inferred← citeshttps://doi.org/10.1007/978-981-99-8034-5_4openalex-snapshot
Analytical Quality by Design
inferred← citeshttps://doi.org/10.1007/s00449-026-03369-9openalex-snapshot
Operationalizing digital twins in biomanufacturing through interoperable process analytical technology
inferred← citeshttps://doi.org/10.1007/s00764-020-00019-yopenalex-snapshot
Application of analytical quality by design approach in method development for the simultaneous estimation of levocetrizine hydrochloride and montelukast sodium in their combined dosage form
inferred← citeshttps://doi.org/10.1007/s00764-023-00246-zopenalex-snapshot
Quality by design approach for the quantitative determination of andrographolide, gallic acid and quercetin from polyherbal tablets by instrumental thin-layer chromatography
inferred← citeshttps://doi.org/10.1007/s00769-017-1270-zopenalex-snapshot
Evolution of quality on pharmaceutical design: regulatory requirement?
inferred← citeshttps://doi.org/10.1007/s00769-024-01587-wopenalex-snapshot
Analytical quality by design (AQbD) in the ICHQ14 guidelines for analytical procedure development
inferred← citeshttps://doi.org/10.1007/s10337-018-3545-xopenalex-snapshot
Simple and Efficient Solution for Robustness Testing in Gradient Elution Liquid Chromatographic Methods
inferred← citeshttps://doi.org/10.1007/s10337-020-03925-9openalex-snapshot
QbD-Enabled Stability-Indicating Assay Method for the Estimation of Linezolid in Newly Developed Gelatin Nanoparticles for Anti-tubercular Therapy
inferred← citeshttps://doi.org/10.1007/s10337-022-04223-2openalex-snapshot
Evolution of Stability-Indicating Method in the Quantification of Related Substances and Degradation Products of Elagolix Sodium: Quality by Design-Driven Approach Utilizing Ultra-high Performance Liquid Chromatography
inferred← citeshttps://doi.org/10.1007/s10337-024-04378-0openalex-snapshot
Systematic Development of a Gradient Elution HPLC Method for the Analysis of Voxelotor and Its Structurally Related Substances Applying Analytical Quality by Design Approach
inferred← citeshttps://doi.org/10.1007/s10337-025-04460-1openalex-snapshot
Quantification of Menthol by Chromatography Applying Analytical Quality by Design
inferred← citeshttps://doi.org/10.1007/s10895-024-04020-0openalex-snapshot
A Novel Spectrofluorimetric Method for Vibegron in the Newly FDA Approved Pharmaceutical Formulation and in Human Plasma: Analytical QbD Strategy for Method Development and Optimization
inferred← citeshttps://doi.org/10.1007/s11094-024-03153-7openalex-snapshot
Analytical Quality by Design Approach for the Development and Validation of Liquid Chromatographic Procedure for the Estimation of Abrocitinib
inferred← citeshttps://doi.org/10.1007/s12247-021-09581-2openalex-snapshot
Evaluation and Monitoring of the API Content of a Portable Near Infrared Instrument Combined with Chemometrics Based on Fluidized Bed Mixing Process
inferred← citeshttps://doi.org/10.1007/s12247-025-10295-yopenalex-snapshot
Design of Experiments-Based RP-HPLC Bioanalytical Method Development and Validation for Ticagrelor Quantification in Rat Plasma with Pharmacokinetic Application
inferred← citeshttps://doi.org/10.1007/s12247-025-10303-1openalex-snapshot
RP-HPLC Method for Simultaneous Estimation of Sulopenem Etzadroxil and Probenecid: Incorporating Design of Experiment and Green Metrics
inferred← citeshttps://doi.org/10.1007/s12247-026-10460-xopenalex-snapshot
Development and Validation of a Cost-Effective, DoE-Optimized RP-HPLC Method for the Quantification of Alogliptin in Human Plasma
inferred← citeshttps://doi.org/10.1007/s12247-026-10711-xopenalex-snapshot
Development and Validation of Stability-Indicating RP-HPLC Method for Nirmatrelvir and Ritonavir: Integration of Quality by Design and Multi-Metric Analytical Evaluation
inferred← citeshttps://doi.org/10.1007/s42452-025-08207-3openalex-snapshot
Stability indicating UV spectrophotometric method development and validation of quercetin and apigenin simultaneously by quality by design approach
inferred← citeshttps://doi.org/10.1007/s43441-026-00930-2openalex-snapshot
A Survey on the Implementation of Analytical Quality by Design in Method Development in the Pharmaceutical Industries of Southeast Brazil: Challenges and Opportunities
inferred← citeshttps://doi.org/10.1007/s44211-024-00538-2openalex-snapshot
A design of experiment based RP-HPLC method for the simultaneous estimation of antihypertensive drugs with greenness assessment
inferred← citeshttps://doi.org/10.1007/s44371-024-00036-4openalex-snapshot
Application of quality by design in the development of HPTLC Method for the estimation of ceritinib in bulk and synthetic mixture
inferred← citeshttps://doi.org/10.1007/s44371-025-00168-1openalex-snapshot
RP-HPLC method development and validation of Abacavir, Lamivudine and Zidovudine in combined pharmaceutical dosage by analytical QbD
inferred← citeshttps://doi.org/10.1016/b978-0-08-102824-7.00022-1openalex-snapshot
Biotechnology products: validation of analytical methods
inferred← citeshttps://doi.org/10.1016/b978-0-12-811065-2.00010-2openalex-snapshot
Applications of MVDA and PAT for Drug Product Development and Manufacturing
inferred← citeshttps://doi.org/10.1016/b978-0-12-814421-3.00012-9openalex-snapshot
Documentation Protocol in Product Development Including Clinical Records
inferred← citeshttps://doi.org/10.1016/b978-0-12-815799-2.00005-8openalex-snapshot
QbD Considerations for Analytical Development
inferred← citeshttps://doi.org/10.1016/b978-0-12-820043-8.00017-7openalex-snapshot
Pharmaceutical product development: A quality by design (QbD) approach
inferred← citeshttps://doi.org/10.1016/b978-0-12-820332-3.00002-9openalex-snapshot
Analytical quality by design for gas chromatographic method development
inferred← citeshttps://doi.org/10.1016/b978-0-12-820332-3.00005-4openalex-snapshot
Analytical quality by design for capillary electrophoresis
inferred← citeshttps://doi.org/10.1016/b978-0-12-820332-3.00007-8openalex-snapshot
Analytical quality by design for high-performance thin-layer chromatography method development
inferred← citeshttps://doi.org/10.1016/b978-0-12-820332-3.00008-xopenalex-snapshot
Risk assessment and design space consideration in analytical quality by design
inferred← citeshttps://doi.org/10.1016/b978-0-443-13466-1.00023-4openalex-snapshot
Biotechnology products: Validation of analytical methods
inferred← citeshttps://doi.org/10.1016/b978-0-443-18655-4.00003-0openalex-snapshot
Quality by design in the pharmaceutical development
inferred← citeshttps://doi.org/10.1016/j.ab.2022.114793openalex-snapshot
An analytical quality by design approach towards a simple and novel HPLC-UV method for quantification of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline
inferred← citeshttps://doi.org/10.1016/j.aca.2021.338217openalex-snapshot
A new approach based on inversion of a partial least squares model searching for a preset analytical target profile. Application to the determination of five bisphenols by liquid chromatography with diode array detector
inferred← citeshttps://doi.org/10.1016/j.chroma.2015.12.080openalex-snapshot
A simultaneous determination of related substances by high performance liquid chromatography in a drug product using quality by design approach
inferred← citeshttps://doi.org/10.1016/j.chroma.2017.07.062openalex-snapshot
Application of quality by design concept to develop a dual gradient elution stability-indicating method for cloxacillin forced degradation studies using combined mixture-process variable models
inferred← citeshttps://doi.org/10.1016/j.chroma.2020.461658openalex-snapshot
A methodology employing retention modeling for achieving control space in liquid chromatography method development using quality by design approach
inferred← citeshttps://doi.org/10.1016/j.chroma.2021.462577openalex-snapshot
Method operable design region obtained with a partial least squares model inversion in the determination of ten polycyclic aromatic hydrocarbons by liquid chromatography with fluorescence detection
inferred← citeshttps://doi.org/10.1016/j.chroma.2022.463494openalex-snapshot
Analytical quality by design-compliant retention modeling for exploring column interchangeabilities in separating ezetimibe and its related substances
inferred← citeshttps://doi.org/10.1016/j.colcom.2023.100709openalex-snapshot
Dialysis is a key factor modulating interactions between critical process parameters during the microfluidic preparation of lipid nanoparticles
inferred← citeshttps://doi.org/10.1016/j.compchemeng.2026.109690openalex-snapshot
CADET-Hub: Online platform for biomanufacturing modeling and stability testing
inferred← citeshttps://doi.org/10.1016/j.cpan.2026.04.006openalex-snapshot
Implementation of analytical quality by design (AQbD) in RP-HPLC method development for quantification of allopurinol in pure and commercial formulations
inferred← citeshttps://doi.org/10.1016/j.ejpb.2020.12.002openalex-snapshot
Harnessing the nano-bio interface: Application of membrane coating to long acting silica particles
inferred← citeshttps://doi.org/10.1016/j.ejps.2018.03.029openalex-snapshot
Application of Quality by Design to optimize a stability-indicating LC method for the determination of ticagrelor and its impurities
inferred← citeshttps://doi.org/10.1016/j.ejps.2025.107268openalex-snapshot
High-performance liquid chromatography method for simultaneous determination of the degradation products of metformin hydrochloride and vildagliptin
inferred← citeshttps://doi.org/10.1016/j.ejps.2026.107561openalex-snapshot
Is a DoE-based approach superior to OFAT for HPLC robustness assessment under ICH Q14? A practical case study
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e28414openalex-snapshot
Development of a robust cell-based potency assay for a coxsackievirus A21 oncolytic virotherapy
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2019.118695openalex-snapshot
aQbD as a platform for IVRT method development – A regulatory oriented approach
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.123255openalex-snapshot
Development of a buccal in vitro permeation method – exploring aQbD implementation
inferred← citeshttps://doi.org/10.1016/j.jchromb.2021.122549openalex-snapshot
In depth investigation of the retention behavior of structurally related β-blockers on RP-HPLC column: Quality by design and quantitative structure-property relationship complementary approaches for optimization and validation
inferred← citeshttps://doi.org/10.1016/j.jchromb.2026.125084openalex-snapshot
Development of a fit-for-purpose method using the analytical quality by design approach for quantifying a sesquiterpenoid and an 8-hydroxyquinoline derivative in a porcine hoof permeation model
inferred← citeshttps://doi.org/10.1016/j.jcoa.2022.100052openalex-snapshot
Analytical quality by design assisted RP-HPLC method for quantifying atorvastatin with green analytical chemistry perspective
inferred← citeshttps://doi.org/10.1016/j.jcoa.2026.100318openalex-snapshot
Analytical Quality by Design approach in the development of a green reversed-phase ultra-high performance liquid chromatography/high-resolution time-of-flight mass spectrometry method for the simultaneous analysis of synthetic antimicrobial and hypotensive peptides
inferred← citeshttps://doi.org/10.1016/j.jddst.2017.06.004openalex-snapshot
Design space and critical points in solid dosage forms
inferred← citeshttps://doi.org/10.1016/j.jics.2026.102538openalex-snapshot
A green chemistry-oriented quality by design approach for sensitive voltammetric determination of ketotifen fumarate using a nano-zirconium oxide-modified electrode
inferred← citeshttps://doi.org/10.1016/j.jim.2016.12.003openalex-snapshot
Evaluation of a digital dispenser for direct curve dilutions in a vaccine potency assay
inferred← citeshttps://doi.org/10.1016/j.jpba.2016.04.022openalex-snapshot
Application of Analytical Quality by Design concept for bilastine and its degradation impurities determination by hydrophilic interaction liquid chromatographic method
inferred← citeshttps://doi.org/10.1016/j.jpba.2017.06.020openalex-snapshot
Life cycle management of analytical methods
inferred← citeshttps://doi.org/10.1016/j.jpba.2018.06.018openalex-snapshot
A Quality by Design (QbD) approach to the development of a gradient high-performance liquid chromatography for the simultaneous assay of curcuminoids and doxorubicin from long-circulating liposomes
inferred← citeshttps://doi.org/10.1016/j.jpba.2018.07.050openalex-snapshot
Risk-based approach for method development in pharmaceutical quality control context: A critical review
inferred← citeshttps://doi.org/10.1016/j.jpba.2019.05.026openalex-snapshot
Quality by Design oriented development of hydrophilic interaction liquid chromatography method for the analysis of amitriptyline and its impurities
inferred← citeshttps://doi.org/10.1016/j.jpba.2019.112910openalex-snapshot
Strategies for stabilizing formulation and QbD assisted development of robust stability indicating method of azilsartan medoxomil/chlorthalidone
inferred← citeshttps://doi.org/10.1016/j.jpba.2020.113309openalex-snapshot
Development of a method of analysis for profiling of the impurities in phenoxymethylpenicillin potassium based on the analytical quality by design concept combined with the degradation mechanism of penicillins
inferred← citeshttps://doi.org/10.1016/j.jpba.2020.113371openalex-snapshot
Updating the European Pharmacopoeia impurity profiling method for terazosin and suggesting alternative columns
inferred← citeshttps://doi.org/10.1016/j.jpba.2020.113729openalex-snapshot
Ultra high-performance liquid chromatography method development for separation of formoterol, budesonide, and related substances using an analytical quality by design approach
inferred← citeshttps://doi.org/10.1016/j.jpba.2021.114203openalex-snapshot
Computer-assisted UHPLC method development and optimization for the determination of albendazole and its related substances
inferred← citeshttps://doi.org/10.1016/j.jpba.2021.114330openalex-snapshot
Multi-attribute method performance profile for quality control of monoclonal antibody therapeutics
inferred← citeshttps://doi.org/10.1016/j.jpba.2021.114417openalex-snapshot
Analytical Lifecycle Management (ALM) and Analytical Quality by Design (AQbD) for analytical procedure development of related substances in tenofovir alafenamide fumarate tablets
inferred← citeshttps://doi.org/10.1016/j.jpba.2022.114911openalex-snapshot
A state of the art in analytical quality-by-design and perspectives in characterization of nano-enabled medicinal products
inferred← citeshttps://doi.org/10.1016/j.jpba.2022.115149openalex-snapshot
Application of design space and quality by design methodologies combined with ultra high-performance liquid chromatography for the optimization of the sample preparation of complex pharmaceutical dosage forms
inferred← citeshttps://doi.org/10.1016/j.jpba.2022.115208openalex-snapshot
Development and optimization of stability-indicating method of ethinylestradiol, levonorgestrel, and their main impurities using quality by design approach
inferred← citeshttps://doi.org/10.1016/j.jpba.2023.115907openalex-snapshot
Enhancing analytical development in the pharmaceutical industry: A DoE-QSRR model for virtual Method Operable Design Region assessment
inferred← citeshttps://doi.org/10.1016/j.jpba.2026.117553openalex-snapshot
Analytical quality by design-based development and validation of a robust impurity analysis method for albumin-bound paclitaxel nanoparticles
inferred← citeshttps://doi.org/10.1016/j.jscs.2023.101772openalex-snapshot
Central composite design (CCD) approach to develop HPLC method for caffeine: Application to coffee samples analysis of Jazan region, Saudi Arabia
inferred← citeshttps://doi.org/10.1016/j.microc.2020.104610openalex-snapshot
Development and optimization of a stability-indicating chromatographic method for verapamil hydrochloride and its impurities in tablets using an analytical quality by design (AQbD) approach
inferred← citeshttps://doi.org/10.1016/j.microc.2020.104626openalex-snapshot
A smartphone-based bioassay for determining relative potency estimated from sigmoidal-response curves and respective measurement uncertainty
inferred← citeshttps://doi.org/10.1016/j.microc.2020.104921openalex-snapshot
Development and validation of a stability indicating HPLC-DAD method for the determination of the peptide stigmurin
inferred← citeshttps://doi.org/10.1016/j.microc.2020.105711openalex-snapshot
A combined approach of green chemistry and Quality-by-Design for sustainable and robust analysis of two newly introduced pharmaceutical formulations treating benign prostate hyperplasia
inferred← citeshttps://doi.org/10.1016/j.microc.2021.106692openalex-snapshot
Application of the lifecycle approach to the development and validation of a chromatographic method for therapeutic drug monitoring of ceftazidime, meropenem, and piperacillin
inferred← citeshttps://doi.org/10.1016/j.microc.2021.106929openalex-snapshot
New HPLC-UV analytical method for quantification of metronidazole: Application to ex vivo ocular kinetic assessments following the administration of thermosensitive ocular in situ gel
inferred← citeshttps://doi.org/10.1016/j.microc.2022.108166openalex-snapshot
Simultaneous estimation of crotamiton and hydrocortisone by RP-UPLC using green analytical principles embedded analytical quality by design (AQbD) method
inferred← citeshttps://doi.org/10.1016/j.microc.2022.108310openalex-snapshot
QbD and Six Sigma quality approach for chromatographic estimation of repurposed simvastatin from nanostructured lipid carriers
inferred← citeshttps://doi.org/10.1016/j.microc.2023.108848openalex-snapshot
Simultaneous estimation of neratinib and naringenin from pharmaceuticals using a stability-indicating liquid chromatographic method: Application to analytical quality by design concept and multi-tool method greenness assessment
inferred← citeshttps://doi.org/10.1016/j.microc.2024.109939openalex-snapshot
Application of analytical quality by design (AQbD) for stability-indicating method development for quantification of nevirapine and its degradation products
inferred← citeshttps://doi.org/10.1016/j.microc.2024.111634openalex-snapshot
A DOE- based sustainable UPLC method for the Quantification of COVID-19 antiviral, Favipiravir, co-administered with prednisolone in rat Plasma, including pharmacokinetic study greenness and whiteness Assessment
inferred← citeshttps://doi.org/10.1016/j.microc.2025.115071openalex-snapshot
Evaluation of integrative AQbD, advanced environmentally benign assessment tools for estimation of Polymyxin B in kidney-on-Chip (RPTEC) media using ESI-LC-MS/MS
inferred← citeshttps://doi.org/10.1016/j.microc.2025.116016openalex-snapshot
Ecofriendly analytical quality by design-based HPLC method for a quintuple-drug combination: assay, forced degradation, dissolution profiling, and greenness assessment
inferred← citeshttps://doi.org/10.1016/j.microc.2026.119061openalex-snapshot
Managing false compliance risk in primaquine analysis: a retrospective AQbD approach guided by measurement uncertainty
inferred← citeshttps://doi.org/10.1016/j.pharma.2023.12.011openalex-snapshot
A brief review on application of design of experiment for the analysis of pharmaceuticals using HPLC
inferred← citeshttps://doi.org/10.1016/j.sampre.2023.100079openalex-snapshot
Quality by design approach with design of experiment for sample preparation techniques
inferred← citeshttps://doi.org/10.1016/j.scca.2026.100212openalex-snapshot
Quality by design- assisted green HPLC and UPLC methods: Advancing sustainable analytical chemistry for climate action - a review
inferred← citeshttps://doi.org/10.1016/j.sciaf.2022.e01109openalex-snapshot
Chromatographic method development for the simultaneous assay of pseudoephedrine hydrochloride and chlorphenamine maleate in oral dosage formulations
inferred← citeshttps://doi.org/10.1016/j.scp.2023.101197openalex-snapshot
Application of advanced environmentally benign assessment tools in determining ternary cardiovascular drug combination by RP-HPLC with analytical quality by design: Application to stability indicating method evaluation
inferred← citeshttps://doi.org/10.1016/j.scp.2026.102450openalex-snapshot
A sustainability-integrated analytical quality by design UPLC–PDA method for amoxapine determination in bulk and tablet formulations: Application to stability studies
inferred← citeshttps://doi.org/10.1016/j.talanta.2023.124481openalex-snapshot
Development and optimization of a LC-MS/MS compatible method for quantification of losartan, hydrochlorothiazide and their impurities using AQbD approach and measurement uncertainty evaluation
inferred← citeshttps://doi.org/10.1016/j.talanta.2026.130236openalex-snapshot
Quality by design-based RP-HPLC methods for pharmaceutical analytical estimation: A review
inferred← citeshttps://doi.org/10.1016/j.techfore.2025.124182openalex-snapshot
Quality-by-design as the pharmaceutical innovation paradigm: mapping the field and proposing a conceptual framework
inferred← citeshttps://doi.org/10.1016/j.trac.2021.116486openalex-snapshot
Supercritical fluid chromatography for pharmaceutical quality control: Current challenges and perspectives
inferred← citeshttps://doi.org/10.1016/j.xphs.2022.08.025openalex-snapshot
Novel Eco-Friendly Stability Indicating Capillary Zone Electrophoresis Method for Determination of Aripiprazole in Tablet Dosage form: DoE Directed Optimization, Development and Method Validation
inferred← citeshttps://doi.org/10.1021/acs.analchem.0c04504openalex-snapshot
Use of Stage-Wise AQbD and an Orthogonality Approach to Develop a Short-Runtime Method for the Simultaneous Quantification of Bosentan and Impurities using UPLC Equipped with PDA and ESI-MS
inferred← citeshttps://doi.org/10.1021/acs.analchem.8b04596openalex-snapshot
Using the Analytical Target Profile to Drive the Analytical Method Lifecycle
inferred← citeshttps://doi.org/10.1021/acs.oprd.9b00238openalex-snapshot
Development and Optimization of Liquid Chromatography Analytical Methods by Using AQbD Principles: Overview and Recent Advances
inferred← citeshttps://doi.org/10.1021/acsomega.2c04013openalex-snapshot
Development of a New Solid-Phase Extraction Base Method for Free Saccharide Content Estimation of Meningococcal Conjugate Vaccines
inferred← citeshttps://doi.org/10.1021/acsomega.4c03065openalex-snapshot
Discovery of Quality by Design-Based Extraction Technology and the Quality Standard of Jinhua Finger Citron Essential Oil
inferred← citeshttps://doi.org/10.1021/acsomega.5c09833openalex-snapshot
Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Arformoterol Tartrate Inhalation Solution Dosage Form via RP-HPLC
inferred← citeshttps://doi.org/10.1038/s41598-022-04931-7openalex-snapshot
Process intensification for the continuous production of an antimicrobial peptide in stably-transformed Sf-9 insect cells
inferred← citeshttps://doi.org/10.1039/c5nj03719kopenalex-snapshot
Dual design spaces for micro-extraction together with the core–shell chromatographic determination of dorzolamide and timolol in rabbit plasma: an example of quality by design method development
inferred← citeshttps://doi.org/10.1039/d2ay02016eopenalex-snapshot
Developing an improved UHPLC method for impurity profile analysis of ceftriaxone using analytical quality by design
inferred← citeshttps://doi.org/10.1039/d2ra00966hopenalex-snapshot
Quality by design approach for green HPLC method development for simultaneous analysis of two thalassemia drugs in biological fluid with pharmacokinetic study
inferred← citeshttps://doi.org/10.1039/d4ay02080dopenalex-snapshot
An AQbD driven stability indicating HPLC method for simultaneous estimation of lamivudine, tenofovir disoproxil fumarate and efavirenz in plasma
inferred← citeshttps://doi.org/10.1055/a-2185-4916openalex-snapshot
Quality by Design in Pharmaceuticals: A Review of its Impact on Regulatory Compliance and Product Quality
inferred← citeshttps://doi.org/10.1063/5.0162969openalex-snapshot
A novel quality by design compliant approach for the determination of albendazole in bulk and pharmaceutical dosage form using RP-HPLC
inferred← citeshttps://doi.org/10.1080/03639045.2017.1412459openalex-snapshot
Applying the methodology of Design of Experiments to stability studies: a Partial Least Squares approach for evaluation of drug stability
inferred← citeshttps://doi.org/10.1080/03639045.2024.2400199openalex-snapshot
Stability-indicating green HPLC method for fixed-dose tablets containing remogliflozin etabonate and teneligliptin: an AQbD approach
inferred← citeshttps://doi.org/10.1080/03639045.2026.2686259openalex-snapshot
Analytical quality by design (AQbD)-based RP-HPLC method development and validation for concurrent determination of meloxicam and chlorhexidine in a novel dental in-situ gel for odontalgia
inferred← citeshttps://doi.org/10.1080/10408347.2019.1615863openalex-snapshot
Quinquennial Review of Progress in Degradation Studies and Impurity Profiling: An Instrumental Perspective Statistics
inferred← citeshttps://doi.org/10.1080/10408347.2023.2253321openalex-snapshot
Drilling into “Quality by Design” Approach for Analytical Methods
inferred← citeshttps://doi.org/10.1080/10408347.2025.2516607openalex-snapshot
Enhancing Pharmaceutical Analysis with Analytical Quality by Design in UHPLC: A Review of Methodological Innovations (2014–2025)
inferred← citeshttps://doi.org/10.1080/10408347.2025.2593506openalex-snapshot
Innovative Analytical Methodologies for Quantification of Efonidipine HCl and Chlorthalidone: A Critical Review
inferred← citeshttps://doi.org/10.1080/10826068.2025.2602603openalex-snapshot
Quality by design (QbD) approach to SE-HPLC method development for cetuximab Monoclonal antibodies
inferred← citeshttps://doi.org/10.1080/10826076.2017.1330211openalex-snapshot
Quality-by-design-based development and validation of a stability-indicating UPLC method for quantification of teriflunomide in the presence of degradation products and its application toin-vitrodissolution
inferred← citeshttps://doi.org/10.1080/10826076.2017.1382377openalex-snapshot
Applications of Monte-Carlo simulation and chemometric techniques for development of bioanalytical liquid chromatography method for estimation of rosuvastatin calcium
inferred← citeshttps://doi.org/10.1080/10826076.2021.1874982openalex-snapshot
Analytical quality by design approach versus conventional approach: Development of HPLC-DAD method for simultaneous determination of etizolam and propranolol hydrochloride
inferred← citeshttps://doi.org/10.1080/10826076.2021.1973027openalex-snapshot
Analytical quality-by-design (AQbD) guided development of a robust HPLC method for the quantification of plumbagin from Plumbago species
inferred← citeshttps://doi.org/10.1080/10826076.2022.2025827openalex-snapshot
Quantitative structure retention relationship (QSRR) approach for assessment of chromatographic behavior of antiviral drugs in the development of liquid chromatographic method
inferred← citeshttps://doi.org/10.1080/10826076.2023.2204238openalex-snapshot
A comprehensive review on QbD driven analytical procedures developed for the analysis of various drugs
inferred← citeshttps://doi.org/10.1080/10826076.2023.2270734openalex-snapshot
Eco-friendly design of experiment based approach for estimation of azelnidipine and olmesartan medoxomil in RP-HPLC: Greenness appraisal
inferred← citeshttps://doi.org/10.1080/10826076.2023.2284713openalex-snapshot
Novel chromatographic methods for fingerprinting the bioactive constituents of herbal medicines used as hepatoprotective and adaptogenic in herbo-mineral regimen
inferred← citeshttps://doi.org/10.1080/10826076.2023.2299670openalex-snapshot
Development and validation of simultaneous HPLC-PDA analysis method for quality control of Hwang-ryeon-hae-dok-tang: An analytical quality by design approach
inferred← citeshttps://doi.org/10.1080/10826076.2025.2569880openalex-snapshot
Optimizing quality and sustainability in drug development: A comprehensive Desidustat stability study using QbD and green chemistry
inferred← citeshttps://doi.org/10.1080/10826076.2026.2636541openalex-snapshot
In-silico tools and Analytical Quality by Design in liquid chromatographic method development
inferred← citeshttps://doi.org/10.1080/10837450.2020.1817073openalex-snapshot
Prediction of saxagliptin stability using a new approach based on Partial Least Squares and Design of Experiments
inferred← citeshttps://doi.org/10.1080/16583655.2023.2252593openalex-snapshot
Ecofriendly analytical quality by design-based method for determining Metronidazole, Lidocaine and Miconazole using RP-HPLC in semisolid dosage form
inferred← citeshttps://doi.org/10.1080/16583655.2024.2415156openalex-snapshot
AQbD-guided stability indicating HPLC method for azelnidipine and chlorthalidone fixed-dose combination tablet: a green approach
inferred← citeshttps://doi.org/10.1080/22297928.2018.1552537openalex-snapshot
Analytical QbD-Integrated Method Development and Validation of Silver Sulphadiazine in Pure Drug and Topical Nanocarrier(s)
inferred← citeshttps://doi.org/10.1080/22297928.2020.1713211openalex-snapshot
Application of Analytical Lifecycle Management and Monte-Carlo Simulation Approach for Development of a Liquid Chromatography Method for Estimation of Nitazoxanide
inferred← citeshttps://doi.org/10.1080/22297928.2020.1810120openalex-snapshot
Stability-Indicating LC Method for Estimation of Nimodipine in Dosage Form and Spiked Serum Using Systematized Design of Experiments (DoE) Approach
inferred← citeshttps://doi.org/10.1080/22297928.2021.1938215openalex-snapshot
Implementing Analytical Quality by Design (AQbD) Approach for Simultaneous Estimation of Tadalafil and Macitentan by RP-HPLC Method
inferred← citeshttps://doi.org/10.1080/22297928.2024.2314529openalex-snapshot
A stability-indicating liquid chromatography - diode array detection method for quantification of febuxostat in pharmaceuticals: a recent application to chemometrics based method development and comparative greenness assessment
inferred← citeshttps://doi.org/10.1080/22297928.2024.2353056openalex-snapshot
Utilizing central composite design (CCD) in the optimization of new HPLC-PDA method for the assay of daridorexant: Application to the analysis in bulk and tablet dosage forms
inferred← citeshttps://doi.org/10.1080/22297928.2024.2357151openalex-snapshot
Design of experiment driven ecofriendly RP-HPLC for simultaneous determination of Cilnidipine and Metoprolol succinate
inferred← citeshttps://doi.org/10.1080/22297928.2024.2376118openalex-snapshot
AQbD based approach for UPLC procedure development for the concurrent quantification of Metformin, Vildagliptin, Dapagliflozin and Sitagliptin in bulk and tablets: Response surface methodology paradigm
inferred← citeshttps://doi.org/10.1080/22297928.2024.2416480openalex-snapshot
Development and validation of an eco-friendly, stability-indicating UV spectroscopic method for trigonelline analysis in nanoformulation using quality by design approach
inferred← citeshttps://doi.org/10.1080/22297928.2025.2563835openalex-snapshot
Quality by design integrated reverse-phase HPLC method for Dolutegravir: Greenness, whiteness, and kinetic insights
inferred← citeshttps://doi.org/10.1093/chromsci/bmaa054openalex-snapshot
Quality by Design Approach to Develop Stability Indicating Method to Quantify Related Substances and Degradation Products of Sacubitril by High Performance Liquid Chromatography
inferred← citeshttps://doi.org/10.1093/chromsci/bmab030openalex-snapshot
Quality-by-Design Approach for Chromatographic Analysis of Metformin, Empagliflozin and Linagliptin
inferred← citeshttps://doi.org/10.1093/chromsci/bmac044openalex-snapshot
Analysis of Fixed-Dose Combination of Three Antihypertensive Drugs by a Green and Quality by Design Approach
inferred← citeshttps://doi.org/10.1093/chromsci/bmad065openalex-snapshot
Using the AQbD Approach, Development and Validation of a Simple, Rapid Stability Indicating Chromatographic Method for Quantification of Related Impurities of Apixaban
inferred← citeshttps://doi.org/10.1093/chromsci/bmaf045openalex-snapshot
Optimized Simultaneous Estimation of Metformin, Teneligliptin, and Pioglitazone in Tablet and Bulk Drug: A Box–Behnken Design Approach for RP-UFLC Method Development and Validation
inferred← citeshttps://doi.org/10.1093/chromsci/bmag012openalex-snapshot
Analytical quality by design (AQbD)-assisted bioanalytical method for the estimation of Lasmiditan in human plasma by reverse phase–high performance liquid chromatography (RP-HPLC)
inferred← citeshttps://doi.org/10.1093/jaoacint/qsab013openalex-snapshot
Quantification of Scopoletin from the Roots of Argyreia Speciosa (Linn. F) Sweet Using HPLC Through the Concept of Design of Experiment
inferred← citeshttps://doi.org/10.1093/jaoacint/qsae020openalex-snapshot
Eco-Friendly Simultaneous Estimation of Ponceau 4R and Carmoisine Employing an Analytical Quality by Design-Aided RP-HPLC Method in Commercial Food Samples Utilizing a Green Ultrasound-Assisted Extraction Technique
inferred← citeshttps://doi.org/10.1093/jaoacint/qsae085openalex-snapshot
Analytical Quality by Design-Assisted Eco-Friendly RP-HPLC Method for the Simultaneous Estimation of Artificial Sweeteners in Commercial Food Samples Utilizing a Green Ultrasound-Assisted Extraction Technique: Greenness, Blueness, and Whiteness Appraisal
inferred← citeshttps://doi.org/10.1098/rsos.220215openalex-snapshot
Analytical quality by design based on design space in reversed-phase-high performance liquid chromatography analysis for simultaneous estimation of metformin, linagliptin and empagliflozin
inferred← citeshttps://doi.org/10.1134/s1061934822070048openalex-snapshot
Multiple Optimization for Extraction of Ethinylestradiol, Levonorgestrel, and Their Main Impurities using Mixture Design
inferred← citeshttps://doi.org/10.1134/s1061934824700333openalex-snapshot
The Problem of Worst-Case Variability in Cleaning Validation and Cross-Contamination Control: A Quality by Design Approach on Some Cephalosporin Residuals
inferred← citeshttps://doi.org/10.1155/2022/2062406openalex-snapshot
Quality-by-Design Principles Applied to the Establishment of a Pharmaceutical Quality Control Laboratory in a Resource-Limited Setting: The Lab Water
inferred← citeshttps://doi.org/10.1159/000496868openalex-snapshot
Developing Robust Standardised Analytical Procedures for Cannabinoid Quantification: Laying the Foundations for an Emerging Cannabis-Based Pharmaceutical Industry
inferred← citeshttps://doi.org/10.11606/d.9.2016.tde-28042016-110201openalex-snapshot
Doseamento microbiológico de neomicina e bacitracina - desenvolvimento e validação de método rápido em microplacas
inferred← citeshttps://doi.org/10.11606/d.9.2019.tde-31072019-120137openalex-snapshot
Desenvolvimento de método colorimétrico para determinação de sulfato de neomicina empregando os conceitos de qualidade por design analítico (AQbD)
inferred← citeshttps://doi.org/10.11606/d.9.2020.tde-19022020-164639openalex-snapshot
Qualidade por >i /i< Analítico (AQbD) aplicado no desenvolvimento e otimização de métodos cromatográficos
inferred← citeshttps://doi.org/10.11606/d.9.2020.tde-19022020-175129openalex-snapshot
Desenvolvimento e otimização de sistemas conservantes empregando os conceitos de Qualidade por >I /I< (QbD) e Tecnologia Analítica de Processos (PAT)
inferred← citeshttps://doi.org/10.11606/d.9.2022.tde-30112022-105305openalex-snapshot
Aplicação da eletroforese capilar - espectrometria de massas para identificação dos produtos de degradação do aripiprazol em medicamentos
inferred← citeshttps://doi.org/10.11606/d.9.2023.tde-18082023-154055openalex-snapshot
Desenvolvimento de método cromatográfico compatível com LC-MS, indicativo de estabilidade para associação de losartana potássica e hidroclorotiazida em comprimidos pela abordagem Quality by Design e avaliação de incertezas
inferred← citeshttps://doi.org/10.1177/14690667211005335openalex-snapshot
Establishment of validated stability indicating purity method based on the stress degradation behavior of gonadotropin-releasing hormone antagonist (ganirelix) in an injectable formulation using HPLC and LC-MS-QTOF
inferred← citeshttps://doi.org/10.1186/s13065-026-01727-yopenalex-snapshot
From design space to green space: an analytical quality by design–assisted high-performance liquid chromatography method for the quantification of triple-combination antihypertensive drugs
inferred← citeshttps://doi.org/10.1186/s43094-021-00229-zopenalex-snapshot
Multivariate optimization of liquid chromatographic conditions for determination of dapagliflozin and saxagliptin, application to an in vitro dissolution and stability studies
inferred← citeshttps://doi.org/10.1186/s43094-021-00266-8openalex-snapshot
Multivariate optimization and evaluation of quaternary mixture in bulk and co-formulated dosage forms by central composite design
inferred← citeshttps://doi.org/10.1186/s43094-021-00286-4openalex-snapshot
QbD approach to HPLC method development and validation of ceftriaxone sodium
inferred← citeshttps://doi.org/10.1186/s43094-021-00396-zopenalex-snapshot
Analytical quality by design approach to RP-HPLC method development and validation for simultaneous estimation of esomeprazole and naproxen in modified-release dosage form
inferred← citeshttps://doi.org/10.1186/s43094-022-00438-0openalex-snapshot
Development and validation of stability indicating UPLC method for the simultaneous estimation of triamterene and hydrochlorothiazide in combined dosage forms using quality by design approach
inferred← citeshttps://doi.org/10.1186/s43094-023-00537-6openalex-snapshot
Assessment of computational approaches in the prediction of spectrogram and chromatogram behaviours of analytes in pharmaceutical analysis: assessment review
inferred← citeshttps://doi.org/10.1186/s43094-024-00706-1openalex-snapshot
AQbD-novel strategy for analytical methods
showing the first 200 of 288
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.