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The Impact of Evolutionary Driving Forces on Human Complex Diseases: A Population Genetics Approach

https://doi.org/10.1155/2016/2079704

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Consanguinity and common adult diseases in Israeli Arab communities

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Analysis ofBRCA1andBRCA2genes in Spanish breast/ovarian cancer patients: A high proportion of mutations unique to Spain and evidence of founder effects

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Germline BRCA1 mutations predispose to pancreatic adenocarcinoma

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Natural selection at genomic regions associated with obesity and type-2 diabetes: East Asians and sub-Saharan Africans exhibit high levels of differentiation at type-2 diabetes regions

inferredcites →https://doi.org/10.1007/s00439-011-1025-6openalex-snapshot

A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk

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Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans

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Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians

inferredcites →https://doi.org/10.1016/j.ajhg.2013.12.010openalex-snapshot

Revisiting the Thrifty Gene Hypothesis via 65 Loci Associated with Susceptibility to Type 2 Diabetes

inferredcites →https://doi.org/10.1016/j.atg.2013.10.002openalex-snapshot

Signatures of natural selection on genetic variants affecting complex human traits

inferredcites →https://doi.org/10.1016/j.canep.2010.04.004openalex-snapshot

Does consanguinity lead to decreased incidence of breast cancer?

inferredcites →https://doi.org/10.1016/j.clinbiochem.2005.11.018openalex-snapshot

Oxidative stress and antioxidant status in non-metastatic prostate cancer and benign prostatic hyperplasia

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From Social to Genetic Structures in Central Asia

inferredcites →https://doi.org/10.1016/j.cub.2008.04.074openalex-snapshot

Natural Selection on Genes that Underlie Human Disease Susceptibility

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Correlation between Genetic and Geographic Structure in Europe

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The hygiene hypothesis: an evolutionary perspective

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Host nutritional status: the neglected virulence factor

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Peto's Paradox: evolution's prescription for cancer prevention

inferredcites →https://doi.org/10.1016/s0140-6736(01)07018-0openalex-snapshot

BRCA1 and BRCA2 in breast cancer

inferredcites →https://doi.org/10.1016/s0140-6736(08)60208-1openalex-snapshot

LDL-cholesterol concentrations: a genome-wide association study

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Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study

inferredcites →https://doi.org/10.1016/s0954-6111(98)90511-xopenalex-snapshot

Variations in hospitalization rates for asthma among Black and minority ethnic communities

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The hitch-hiking effect of a favourable gene

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The hitch-hiking effect of a favourable gene

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Genetic evidence for a higher female migration rate in humans

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Initial sequencing and analysis of the human genome

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Genetic evidence of an early exit of Homo sapiens sapiens from Africa through eastern Africa

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Cancer and ageing in mice and men

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A haplotype map of the human genome

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Natural selection on protein-coding genes in the human genome

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A new radiocarbon revolution and the dispersal of modern humans in Eurasia

inferredcites →https://doi.org/10.1038/nature05911openalex-snapshot

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

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Genome-wide detection and characterization of positive selection in human populations

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A second generation human haplotype map of over 3.1 million SNPs

inferredcites →https://doi.org/10.1038/nature09298openalex-snapshot

Integrating common and rare genetic variation in diverse human populations

inferredcites →https://doi.org/10.1038/nature09710openalex-snapshot

Genetic history of an archaic hominin group from Denisova Cave in Siberia

inferredcites →https://doi.org/10.1038/nature10659openalex-snapshot

New gene functions in megakaryopoiesis and platelet formation

inferredcites →https://doi.org/10.1038/nature11582openalex-snapshot

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

inferredcites →https://doi.org/10.1038/nature11632openalex-snapshot

An integrated map of genetic variation from 1,092 human genomes

inferredcites →https://doi.org/10.1038/nature12886openalex-snapshot

The complete genome sequence of a Neanderthal from the Altai Mountains

inferredcites →https://doi.org/10.1038/nature12961openalex-snapshot

The genomic landscape of Neanderthal ancestry in present-day humans

inferredcites →https://doi.org/10.1038/ng.120openalex-snapshot

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

inferredcites →https://doi.org/10.1038/ng.2360openalex-snapshot

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

inferredcites →https://doi.org/10.1038/ng.2384openalex-snapshot

Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome

inferredcites →https://doi.org/10.1038/ng.506openalex-snapshot

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

inferredcites →https://doi.org/10.1038/ng.717openalex-snapshot

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

inferredcites →https://doi.org/10.1038/ng.732openalex-snapshot

Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3

inferredcites →https://doi.org/10.1038/ng.76openalex-snapshot

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

inferredcites →https://doi.org/10.1038/ng1001-223openalex-snapshot

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

inferredcites →https://doi.org/10.1038/nrg2506openalex-snapshot

Genetics and the understanding of selection

inferredcites →https://doi.org/10.1038/nrg2632openalex-snapshot

Spatial patterns of variation due to natural selection in humans

inferredcites →https://doi.org/10.1038/nrg2698openalex-snapshot

From evolutionary genetics to human immunology: how selection shapes host defence genes

inferredcites →https://doi.org/10.1038/nrg999openalex-snapshot

Signatures of natural selection in the human genome

inferredcites →https://doi.org/10.1038/sj.ejhg.5200898openalex-snapshot

Linkage of aggressive prostate cancer to chromosome 7q31-33 in German prostate cancer families

inferredcites →https://doi.org/10.1046/j.1464-410x.2003.04167.xopenalex-snapshot

Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial

inferredcites →https://doi.org/10.1073/pnas.0507611102openalex-snapshot

Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa

inferredcites →https://doi.org/10.1073/pnas.0906079106openalex-snapshot

Consanguinity, human evolution, and complex diseases

inferredcites →https://doi.org/10.1084/jem.20082779openalex-snapshot

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

inferredcites →https://doi.org/10.1086/302913openalex-snapshot

Genomewide Search in Canadian Families with Inflammatory Bowel Disease Reveals Two Novel Susceptibility Loci

inferredcites →https://doi.org/10.1086/342506openalex-snapshot

Contribution of BRCA1 and BRCA2 Mutations to Breast and Ovarian Cancer in Pakistan

inferredcites →https://doi.org/10.1086/425938openalex-snapshot

The Genetic or Mythical Ancestry of Descent Groups: Lessons from the Y Chromosome

inferredcites →https://doi.org/10.1086/516757openalex-snapshot

The Himalayas as a Directional Barrier to Gene Flow

inferredcites →https://doi.org/10.1093/carcin/bgi267openalex-snapshot

Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study

inferredcites →https://doi.org/10.1093/genetics/123.4.887openalex-snapshot

The "hitchhiking effect" revisited.

inferredcites →https://doi.org/10.1093/genetics/131.2.479openalex-snapshot

Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data.

inferredcites →https://doi.org/10.1093/hmg/12.4.415openalex-snapshot

Identification of multiple loci for Alzheimer disease in a consanguineous Israeli-Arab community

inferredcites →https://doi.org/10.1093/jnci/djm203openalex-snapshot

Breast Cancer Risk Among Male BRCA1 and BRCA2 Mutation Carriers

inferredcites →https://doi.org/10.1093/molbev/msh214openalex-snapshot

Genetic Evidence for Unequal Effective Population Sizes of Human Females and Males

inferredcites →https://doi.org/10.1093/molbev/msh252openalex-snapshot

Disentangling the Effects of Demography and Selection in Human History

inferredcites →https://doi.org/10.1093/molbev/msr151openalex-snapshot

Crohn's Disease and Genetic Hitchhiking at IBD5

inferredcites →https://doi.org/10.1093/molbev/mss259openalex-snapshot

Anisotropic Isolation by Distance: The Main Orientations of Human Genetic Differentiation

inferredcites →https://doi.org/10.1097/01.aog.0000187892.78392.3fopenalex-snapshot

BRCA-Mutation–Associated Fallopian Tube Carcinoma

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Levels of genetic polymorphism: marker loci versus quantitative traits

inferredcites →https://doi.org/10.1098/rstb.2011.0266openalex-snapshot

Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules

inferredcites →https://doi.org/10.1101/gr.087577.108openalex-snapshot

Signals of recent positive selection in a worldwide sample of human populations

inferredcites →https://doi.org/10.1111/eva.12045openalex-snapshot

The impact of natural selection on health and disease: uses of the population genetics approach in humans

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The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

inferredcites →https://doi.org/10.1111/j.1558-5646.1993.tb01215.xopenalex-snapshot

ISOLATION BY DISTANCE IN EQUILIBRIUM AND NON-EQUILIBRIUM POPULATIONS

inferredcites →https://doi.org/10.1126/science.1058040openalex-snapshot

The Sequence of the Human Genome

inferredcites →https://doi.org/10.1126/science.1078311openalex-snapshot

Genetic Structure of Human Populations

inferredcites →https://doi.org/10.1126/science.1109792openalex-snapshot

Single, Rapid Coastal Settlement of Asia Revealed by Analysis of Complete Mitochondrial Genomes

inferredcites →https://doi.org/10.1126/science.1124309openalex-snapshot

Positive Natural Selection in the Human Lineage

inferredcites →https://doi.org/10.1126/science.1188021openalex-snapshot

A Draft Sequence of the Neandertal Genome

inferredcites →https://doi.org/10.1126/science.1209202openalex-snapshot

The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans

inferredcites →https://doi.org/10.1126/science.1224344openalex-snapshot

A High-Coverage Genome Sequence from an Archaic Denisovan Individual

inferredcites →https://doi.org/10.1126/science.1245938openalex-snapshot

Resurrecting Surviving Neandertal Lineages from Modern Human Genomes

inferredcites →https://doi.org/10.1126/science.273.5281.1516openalex-snapshot

The Future of Genetic Studies of Complex Human Diseases

inferredcites →https://doi.org/10.1136/bmj.299.6705.953openalex-snapshot

Ethnic differences in consultation rates in urban general practice.

inferredcites →https://doi.org/10.1136/bmj.299.6710.1259openalex-snapshot

Hay fever, hygiene, and household size.

inferredcites →https://doi.org/10.1146/annurev.genet.36.050802.093940openalex-snapshot

Estimating F-Statistics

inferredcites →https://doi.org/10.1158/1055-9965.epi-05-0459openalex-snapshot

No Association Between Glutathione Peroxidase Pro198Leu Polymorphism and Breast Cancer Risk

inferredcites →https://doi.org/10.1158/1055-9965.epi-05-0471openalex-snapshot

High Serum Selenium and Reduced Risk of Advanced Colorectal Adenoma in a Colorectal Cancer Early Detection Program

inferredcites →https://doi.org/10.1158/1078-0432.ccr-09-0797openalex-snapshot

Recent Natural Selection Identifies a Genetic Variant in a Regulatory Subunit of Protein Phosphatase 2A that Associates with Altered Cancer Risk and Survival

inferredcites →https://doi.org/10.1159/000102147openalex-snapshot

Consanguineous Marriages and Their Effects on Common Adult Diseases: Studies from an Endogamous Population

inferredcites →https://doi.org/10.1159/000362447openalex-snapshot

Investigating the Potential Effect of Consanguinity on Type 2 Diabetes Susceptibility in a Saudi Population

inferredcites →https://doi.org/10.1164/ajrccm/148.1.10openalex-snapshot

Race and Gender Differences in Respiratory Illness Prevalence and Their Relationship to Environmental Exposures in Children 7 to 14 Years of Age

inferredcites →https://doi.org/10.1177/146642409211200403openalex-snapshot

Suspected Synergism Between Consanguinity and Familial Aggregation in Type 2 Diabetes Mellitus in Saudi Arabia

inferredcites →https://doi.org/10.1177/147323000603400209openalex-snapshot

Antioxidant Enzyme Activities and Lipid Peroxidation Levels in Erythrocytes of Patients with Oesophageal and Gastric Cancer

inferredcites →https://doi.org/10.1186/1471-2156-7-56openalex-snapshot

Polymorphism analysis of six selenoprotein genes: support for a selective sweep at the glutathione peroxidase 1 locus (3p21) in Asian populations

inferredcites →https://doi.org/10.1186/1471-2350-12-10openalex-snapshot

Testing the thrifty gene hypothesis: the Gly482Ser variant in PPARGC1Ais associated with BMI in Tongans

inferredcites →https://doi.org/10.1186/1471-2350-12-55openalex-snapshot

Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease

inferredcites →https://doi.org/10.1212/01.wnl.0000178744.42953.b7openalex-snapshot

Familial aggregation, the PDE4D gene, and ischemic stroke in a genetically isolated population

inferredcites →https://doi.org/10.1371/journal.pbio.0020286openalex-snapshot

Population History and Natural Selection Shape Patterns of Genetic Variation in 132 Genes

inferredcites →https://doi.org/10.1371/journal.pbio.0030170openalex-snapshot

A Scan for Positively Selected Genes in the Genomes of Humans and Chimpanzees

inferredcites →https://doi.org/10.1371/journal.pbio.0040072openalex-snapshot

A Map of Recent Positive Selection in the Human Genome

inferredcites →https://doi.org/10.1371/journal.pgen.0020064openalex-snapshot

Balancing Selection and Its Effects on Sequences in Nearby Genome Regions

inferredcites →https://doi.org/10.1371/journal.pgen.1002886openalex-snapshot

A Quantitative Comparison of the Similarity between Genes and Geography in Worldwide Human Populations

inferredcites →https://doi.org/10.1371/journal.pone.0001206openalex-snapshot

Negative Selection on BRCA1 Susceptibility Alleles Sheds Light on the Population Genetics of Late-Onset Diseases and Aging Theory

inferredcites →https://doi.org/10.1371/journal.pone.0003519openalex-snapshot

Genome-Wide Analysis of Single Nucleotide Polymorphisms Uncovers Population Structure in Northern Europe

inferredcites →https://doi.org/10.1371/journal.pone.0010284openalex-snapshot

Formulating a Historical and Demographic Model of Recent Human Evolution Based on Resequencing Data from Noncoding Regions

inferredcites →https://doi.org/10.1373/clinchem.2010.157016openalex-snapshot

Genetics of Type 2 Diabetes

inferredcites →https://doi.org/10.1373/clinchem.2014.237016openalex-snapshot

The Sequence of the Human Genome

inferredcites →https://doi.org/10.1385/endo:9:2:139openalex-snapshot

The Thrifty Genotype in Type 2 Diabetes: An Unfinished Symphony Moving to Its Finale?

inferredcites →https://doi.org/10.1677/joe.1.05971openalex-snapshot

Selenium and endocrine systems

inferredcites →https://doi.org/10.2105/ajph.90.3.428openalex-snapshot

The effects of race/ethnicity and income on early childhood asthma prevalence and health care use

inferredcites →https://doi.org/10.2337/diacare.21.6.936openalex-snapshot

High Prevalence of Diabetes in Bahrainis: Associations with ethnicity and raised plasma cholesterol

inferredcites →https://doi.org/10.3109/02770909909087294openalex-snapshot

Asthma Hospitalization Trends in California, 1983-1996

inferredcites →https://doi.org/10.3109/15622970701849960openalex-snapshot

The rate of consanguineous marriages among parents of schizophrenic patients in the Arab Bedouin population in Southern Israel

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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