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TP53 Mutations Promote Immunogenic Activity in Breast Cancer
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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p53 Binds to Estrogen Receptor 1 Promoter in Human Breast Cancer Cells
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Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
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Immunity, Inflammation, and Cancer
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Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
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Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
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Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
inferredcites →https://doi.org/10.1016/j.immuni.2016.10.021openalex-snapshot
Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells
inferredcites →https://doi.org/10.1016/j.semcancer.2015.03.004openalex-snapshot
Immune evasion in cancer: Mechanistic basis and therapeutic strategies
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A Comprehensive Immunologic Portrait of Triple-Negative Breast Cancer
inferredcites →https://doi.org/10.1016/j.tranon.2018.07.012openalex-snapshot
Immunogenomics Analysis Reveals that TP53 Mutations Inhibit Tumor Immunity in Gastric Cancer
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Cytokine patterns in patients with cancer: a systematic review
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Products of the major histocompatibility complex and their relationship to the immune response
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Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer
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Regulatory T cells in cancer immunotherapy
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Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
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Comprehensive molecular portraits of human breast tumours
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Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
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p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1
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Inferring tumour purity and stromal and immune cell admixture from expression data
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Robust enumeration of cell subsets from tissue expression profiles
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Combination cancer immunotherapies tailored to the tumour microenvironment
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Cancer immunotherapy and the value of cure
inferredcites →https://doi.org/10.1038/nri.2016.99openalex-snapshot
Emerging roles of p53 and other tumour-suppressor genes in immune regulation
inferredcites →https://doi.org/10.1038/s41418-018-0126-3openalex-snapshot
TP53 gain-of-function mutation promotes inflammation in glioblastoma
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Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
inferredcites →https://doi.org/10.1056/nejmoa1500596openalex-snapshot
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
inferredcites →https://doi.org/10.1073/pnas.0506580102openalex-snapshot
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
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A chemical method for fast and sensitive detection of DNA synthesis in vivo
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Tumor STAT1 Transcription Factor Activity Enhances Breast Tumor Growth and Immune Suppression Mediated by Myeloid-derived Suppressor Cells
inferredcites →https://doi.org/10.1074/jbc.m302637200openalex-snapshot
STAT-1 Interacts with p53 to Enhance DNA Damage-induced Apoptosis
inferredcites →https://doi.org/10.1080/028418600750013096openalex-snapshot
TP53Mutation is an Independent Prognostic Marker for Poor Outcome in Both Node-negative and Node-positive Breast Cancer
inferredcites →https://doi.org/10.1080/2162402x.2016.1214789openalex-snapshot
Characterization of cytokinome landscape for clinical responses in human cancers
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Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors
inferredcites →https://doi.org/10.1093/nar/gkn673openalex-snapshot
CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens
inferredcites →https://doi.org/10.1093/nar/gkw1092openalex-snapshot
KEGG: new perspectives on genomes, pathways, diseases and drugs
inferredcites →https://doi.org/10.1097/cco.0000000000000234openalex-snapshot
Prognostic and predictive immune gene signatures in breast cancer
inferredcites →https://doi.org/10.1097/md.0000000000004321openalex-snapshot
Integrative exploration of genomic profiles for triple negative breast cancer identifies potential drug targets
inferredcites →https://doi.org/10.1101/cshperspect.a001107openalex-snapshot
Mutant p53 Gain-of-Function in Cancer
inferredcites →https://doi.org/10.1101/cshperspect.a001883openalex-snapshot
Tumor Suppressive Functions of p53
inferredcites →https://doi.org/10.1101/cshperspect.a026104openalex-snapshot
The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression
inferredcites →https://doi.org/10.1101/gr.220533.117openalex-snapshot
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity
inferredcites →https://doi.org/10.1111/j.1349-7006.2009.01303.xopenalex-snapshot
Cancer/testis (CT) antigens: Potential targets for immunotherapy
inferredcites →https://doi.org/10.1111/j.2517-6161.1995.tb02031.xopenalex-snapshot
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
inferredcites →https://doi.org/10.1126/science.1905840openalex-snapshot
p53 Mutations in Human Cancers
inferredcites →https://doi.org/10.1126/science.aaa1348openalex-snapshot
Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
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The future of immune checkpoint therapy
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A p53-regulated immune checkpoint relevant to cancer
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Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
inferredcites →https://doi.org/10.1158/0008-5472.can-10-3211openalex-snapshot
Human NK Cells Are Alerted to Induction of p53 in Cancer Cells by Upregulation of the NKG2D Ligands ULBP1 and ULBP2
inferredcites →https://doi.org/10.1158/0008-5472.can-11-4134openalex-snapshot
The Human TLR Innate Immune Gene Family Is Differentially Influenced by DNA Stress and p53 Status in Cancer Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-16-2832openalex-snapshot
Local Activation of p53 in the Tumor Microenvironment Overcomes Immune Suppression and Enhances Antitumor Immunity
inferredcites →https://doi.org/10.1158/0008-5472.can-16-3478openalex-snapshot
Immune Gene Expression Is Associated with Genomic Aberrations in Breast Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-13-3271openalex-snapshot
Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti–PD-1 Therapy
inferredcites →https://doi.org/10.1158/1078-0432.ccr-16-0066openalex-snapshot
Genomic Approaches to Understanding Response and Resistance to Immunotherapy
inferredcites →https://doi.org/10.1158/1535-7163.mct-14-0983openalex-snapshot
PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy
inferredcites →https://doi.org/10.1158/1535-7163.mct-17-0386openalex-snapshot
Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers
inferredcites →https://doi.org/10.1158/1538-7445.am2012-3948openalex-snapshot
Abstract 3948: Proteome analysis of ovarian cancer cell lines under hypoxic conditon by two-dimensional difference gel electrophoresis (2D-DIGE)
inferredcites →https://doi.org/10.1158/1538-7445.sabcs14-pd1-6openalex-snapshot
Abstract PD1-6: Inhibition of PD-L1 by MPDL3280A leads to clinical activity in patients with metastatic triple-negative breast cancer
inferredcites →https://doi.org/10.1159/000353099openalex-snapshot
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
inferredcites →https://doi.org/10.1159/000453569openalex-snapshot
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
inferredcites →https://doi.org/10.1186/1471-2105-14-7openalex-snapshot
GSVA: gene set variation analysis for microarray and RNA-Seq data
inferredcites →https://doi.org/10.1186/s12885-015-1880-yopenalex-snapshot
Genomic profiling of CHEK2*1100delC-mutated breast carcinomas
inferredcites →https://doi.org/10.1186/s13045-018-0578-4openalex-snapshot
Lessons learned from the blockade of immune checkpoints in cancer immunotherapy
inferredcites →https://doi.org/10.1186/s13059-016-0995-zopenalex-snapshot
Widespread parainflammation in human cancer
inferredcites →https://doi.org/10.1200/jco.1995.13.11.2745openalex-snapshot
p53 Status predicts survival in breast cancer patients treated with or without postoperative radiotherapy: a novel hypothesis based on clinical findings.
inferredcites →https://doi.org/10.1200/jco.2015.64.8931openalex-snapshot
Pembrolizumab in Patients With Advanced Triple-Negative Breast Cancer: Phase Ib KEYNOTE-012 Study
inferredcites →https://doi.org/10.1677/joe.0.1800497openalex-snapshot
Regulation of estrogen receptor-alpha expression by the tumor suppressor gene p53 in MCF-7 cells
inferredcites →https://doi.org/10.17615/85ph-f542openalex-snapshot
Understanding and treating triple-negative breast cancer
inferredcites →https://doi.org/10.18632/oncotarget.13483openalex-snapshot
TP53mutations, expression and interaction networks in human cancers
inferredcites →https://doi.org/10.21873/anticanres.11777openalex-snapshot
Clinical Study on the Medical Value of Combination Therapy Involving Adoptive Immunotherapy and Chemotherapy for Stage IV Colorectal Cancer (COMVI Study)
inferredcites →https://doi.org/10.3389/fimmu.2017.01679openalex-snapshot
Neoantigens Generated by Individual Mutations and Their Role in Cancer Immunity and Immunotherapy
inferredcites →https://doi.org/10.4049/jimmunol.155.8.3877openalex-snapshot
Alpha and β chemokines induce NK cell migration and enhance NK-mediated cytolysis
inferredcites →https://doi.org/10.4049/jimmunol.172.5.3119openalex-snapshot
Coordinate Expression of Cytokines and Chemokines by NK Cells during Murine Cytomegalovirus Infection
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Personal neoantigen cancer vaccines
inferredcites →https://doi.org/10.5351/csam.2015.22.6.665openalex-snapshot
ppcor: An R Package for a Fast Calculation to Semi-partial Correlation Coefficients
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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P53: A Guardian of Immunity Becomes Its Saboteur through Mutation
inferred← citeshttps://doi.org/10.3390/ijms232314937openalex-snapshot
Genetic Heterogeneity, Tumor Microenvironment and Immunotherapy in Triple-Negative Breast Cancer
inferred← citeshttps://doi.org/10.3390/ijms241915033openalex-snapshot
Unveiling the Anti-Cancer Potential of Onoceranoid Triterpenes from Lansium domesticum Corr. cv. kokosan: An In Silico Study against Estrogen Receptor Alpha
inferred← citeshttps://doi.org/10.3390/ijms27010138openalex-snapshot
Decoding Breast Cancer: Emerging Molecular Biomarkers and Novel Therapeutic Targets for Precision Medicine
inferred← citeshttps://doi.org/10.4254/wjh.v14.i12.1997openalex-snapshot
Immunological classification of hepatitis B virus-positive hepatocellular carcinoma by transcriptome analysis
inferred← citeshttps://doi.org/10.6084/m9.figshare.16633254openalex-snapshot
Additional file 1 of A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.16633257openalex-snapshot
Additional file 2 of A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.16633260openalex-snapshot
Additional file 3 of A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.16633263openalex-snapshot
Additional file 4 of A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.16633266openalex-snapshot
Additional file 5 of A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.16633269openalex-snapshot
Additional file 6 of A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.16633272openalex-snapshot
Additional file 7 of A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.16633275openalex-snapshot
Additional file 8 of A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.16633278openalex-snapshot
Additional file 9 of A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma
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