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p38 Inhibitors Prevent TGF-β–Induced Myofibroblast Transdifferentiation in Human Tenon Fibroblasts

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cm.10098openalex-snapshot
Smad3 mediates the TGF‐β‐induced contraction of type I collagen gels by mouse embryo fibroblasts
inferredcites →https://doi.org/10.1006/bbrc.1998.9443openalex-snapshot
Upregulated Expression of Fibroblast Growth Factor (FGF) Receptors by Transforming Growth Factor-β1 (TGF-β1) Mediates Enhanced Mitogenic Responses to FGFs in Cultured Human Lung Fibroblasts
inferredcites →https://doi.org/10.1006/excr.2000.4869openalex-snapshot
Transforming Growth Factor-β1 Promotes the Morphological and Functional Differentiation of the Myofibroblast
inferredcites →https://doi.org/10.1006/exer.1996.0044openalex-snapshot
Transforming Growth Factor-β1 Induces α-Smooth Muscle-Actin Expression in Cultured Human and Monkey Trabecular Meshwork
inferredcites →https://doi.org/10.1006/exer.2002.2066openalex-snapshot
TGFβ Induced Myofibroblast Differentiation of Rabbit Keratocytes Requires Synergistic TGFβ, PDGF and Integrin Signaling
inferredcites →https://doi.org/10.1007/bf00193944openalex-snapshot
Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity
inferredcites →https://doi.org/10.1007/bf02147594openalex-snapshot
Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
inferredcites →https://doi.org/10.1007/s004170000252openalex-snapshot
Transforming growth factor β2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development
inferredcites →https://doi.org/10.1016/0092-8674(90)90448-nopenalex-snapshot
TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop
inferredcites →https://doi.org/10.1016/j.copbio.2003.08.006openalex-snapshot
Mechanisms of force generation and transmission by myofibroblasts
inferredcites →https://doi.org/10.1016/s0002-9440(10)61776-2openalex-snapshot
Mechanical Tension Controls Granulation Tissue Contractile Activity and Myofibroblast Differentiation
inferredcites →https://doi.org/10.1016/s0002-9440(10)63562-6openalex-snapshot
Mediation of Transforming Growth Factor-β1-Stimulated Matrix Contraction by Fibroblasts
inferredcites →https://doi.org/10.1016/s0002-9440(10)65334-5openalex-snapshot
The Compliance of Collagen Gels Regulates Transforming Growth Factor-β Induction of α-Smooth Muscle Actin in Fibroblasts
inferredcites →https://doi.org/10.1016/s0021-9258(17)31269-3openalex-snapshot
Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β
inferredcites →https://doi.org/10.1016/s0021-9258(17)35666-1openalex-snapshot
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.
inferredcites →https://doi.org/10.1016/s0021-9258(18)68561-8openalex-snapshot
Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.
inferredcites →https://doi.org/10.1016/s0962-8924(03)00057-6openalex-snapshot
Fibroblast biology in three-dimensional collagen matrices
inferredcites →https://doi.org/10.1038/12971openalex-snapshot
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response
inferredcites →https://doi.org/10.1038/294691a0openalex-snapshot
Are stress fibres contractile?
inferredcites →https://doi.org/10.1038/35043051openalex-snapshot
How cells read TGF-β signals
inferredcites →https://doi.org/10.1038/nature02006openalex-snapshot
Smad-dependent and Smad-independent pathways in TGF-β family signalling
inferredcites →https://doi.org/10.1038/nrm809openalex-snapshot
Myofibroblasts and mechano-regulation of connective tissue remodelling
inferredcites →https://doi.org/10.1042/cs20020150openalex-snapshot
Role of transforming growth factor β in conjunctival scarring
inferredcites →https://doi.org/10.1046/j.1523-1747.1999.00477.xopenalex-snapshot
Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3
inferredcites →https://doi.org/10.1046/j.1523-1747.2002.01719.xopenalex-snapshot
Role of p38 MAPK in Transforming Growth Factor β Stimulation of Collagen Production by Scleroderma and Healthy Dermal Fibroblasts
inferredcites →https://doi.org/10.1056/nejm199909023411006openalex-snapshot
Cutaneous Wound Healing
inferredcites →https://doi.org/10.1056/nejm200005043421807openalex-snapshot
Role of Transforming Growth Factor β in Human Disease
inferredcites →https://doi.org/10.1074/jbc.271.17.10188openalex-snapshot
Transforming Growth Factors β1, β2, and β3 and Their Receptors Are Differentially Regulated during Normal and Impaired Wound Healing
inferredcites →https://doi.org/10.1074/jbc.272.16.10948openalex-snapshot
A Transforming Growth Factor β (TGFβ) Control Element Drives TGFβ-induced Stimulation of Smooth Muscle α-Actin Gene Expression in Concert with Two CArG Elements
inferredcites →https://doi.org/10.1074/jbc.274.13.8949openalex-snapshot
ATF-2 Is a Common Nuclear Target of Smad and TAK1 Pathways in Transforming Growth Factor-β Signaling
inferredcites →https://doi.org/10.1074/jbc.274.2.918openalex-snapshot
Differences in the Regulation of Fibroblast Contraction of Floating Versus Stressed Collagen Matrices
inferredcites →https://doi.org/10.1074/jbc.274.34.24211openalex-snapshot
A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration
inferredcites →https://doi.org/10.1074/jbc.274.38.27161openalex-snapshot
Involvement of the p38 Mitogen-activated Protein Kinase Pathway in Transforming Growth Factor-β-induced Gene Expression
inferredcites →https://doi.org/10.1074/jbc.m000893200openalex-snapshot
Transforming Growth Factor-β1-induced Activation of the ERK Pathway/Activator Protein-1 in Human Lung Fibroblasts Requires the Autocrine Induction of Basic Fibroblast Growth Factor
inferredcites →https://doi.org/10.1074/jbc.m003339200openalex-snapshot
Synergistic Cooperation between Sp1 and Smad3/Smad4 Mediates Transforming Growth Factor β1 Stimulation of α2(I)-Collagen (COL1A2) Transcription
inferredcites →https://doi.org/10.1074/jbc.m006442200openalex-snapshot
Sp1 and Smad Proteins Cooperate to Mediate Transforming Growth Factor-β1-induced α2(I) Collagen Expression in Human Glomerular Mesangial Cells
inferredcites →https://doi.org/10.1083/jcb.103.6.2787openalex-snapshot
A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation.
inferredcites →https://doi.org/10.1083/jcb.122.1.103openalex-snapshot
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
inferredcites →https://doi.org/10.1083/jcb.124.4.401openalex-snapshot
Fibroblasts, myofibroblasts, and wound contraction
inferredcites →https://doi.org/10.1083/jcb.153.3.569openalex-snapshot
Rho-Kinase–Mediated Contraction of Isolated Stress Fibers
inferredcites →https://doi.org/10.1091/mbc.01-08-0398openalex-snapshot
Transforming Growth Factor-β–induced Mobilization of Actin Cytoskeleton Requires Signaling by Small GTPases Cdc42 and RhoA
inferredcites →https://doi.org/10.1091/mbc.12.9.2730openalex-snapshot
Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity
inferredcites →https://doi.org/10.1091/mbc.e02-05-0291openalex-snapshot
Modulation of Fibroblast Morphology and Adhesion during Collagen Matrix Remodeling
inferredcites →https://doi.org/10.1091/mbc.e02-11-0729openalex-snapshot
α-Smooth Muscle Actin Is Crucial for Focal Adhesion Maturation in Myofibroblasts
inferredcites →https://doi.org/10.1091/mbc.e04-04-0353openalex-snapshot
A Critical Role of Tropomyosins in TGF-β Regulation of the Actin Cytoskeleton and Cell Motility in Epithelial Cells
inferredcites →https://doi.org/10.1093/emboj/18.1.179openalex-snapshot
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1–TAK1 in the BMP signaling pathway
inferredcites →https://doi.org/10.1093/emboj/19.8.1745openalex-snapshot
Transcriptional control by the TGF‐β/Smad signaling system
inferredcites →https://doi.org/10.1093/emboj/cdf366openalex-snapshot
TGF‐β receptor‐activated p38 MAP kinase mediates Smad‐independent TGF‐β responses
inferredcites →https://doi.org/10.1093/emboj/cdf643openalex-snapshot
Smad‐dependent GADD45β expression mediates delayed activation of p38 MAP kinase by TGF‐β
inferredcites →https://doi.org/10.1096/fasebj.13.13.1774openalex-snapshot
Connective tissue growth factor mediates transforming growth factor β‐induced collagen synthesis: down‐regulation by cAMP
inferredcites →https://doi.org/10.1096/fj.03-1273revopenalex-snapshot
TGF‐β signaling and the fibrotic response
inferredcites →https://doi.org/10.1097/00055735-199804000-00002openalex-snapshot
Classification of filtering blebs in trabeculectomy: biomicroscopy and functionality
inferredcites →https://doi.org/10.1128/mcb.22.7.2304-2317.2002openalex-snapshot
Opposing Roles of the Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Cascades in Ras-Mediated Downregulation of Tropomyosin
inferredcites →https://doi.org/10.1167/iovs.02-0973openalex-snapshot
Myofibroblast Differentiation of Normal Human Keratocytes and hTERT, Extended-Life Human Corneal Fibroblasts
inferredcites →https://doi.org/10.1167/iovs.03-0660openalex-snapshot
Involvement of CTGF in TGF-β1–Stimulation of Myofibroblast Differentiation and Collagen Matrix Contraction in the Presence of Mechanical Stress
inferredcites →https://doi.org/10.1167/iovs.03-1276openalex-snapshot
p38 MAPK Mediates the Expression of Type I Collagen Induced by TGF-β2 in Human Retinal Pigment Epithelial Cells ARPE-19
inferredcites →https://doi.org/10.1172/jci114065openalex-snapshot
Correlation of fibrosis and transforming growth factor-beta type 2 levels in the eye.
inferredcites →https://doi.org/10.1242/jcs.108.3.985openalex-snapshot
Neutralisation of TGF-β1 and TGF-β2 or exogenous addition of TGF-β3 to cutaneous rat wounds reduces scarring
inferredcites →https://doi.org/10.1242/jcs.114.18.3285openalex-snapshot
Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors
inferredcites →https://doi.org/10.1242/jcs.115.15.3193openalex-snapshot
p38 mitogen-activated protein kinase is required for TGFβ-mediated fibroblastic transdifferentiation and cell migration

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3912950openalex-extracted
Fibrosis Without Myofibroblasts Revealed by Genetic Analysis of PDGFRα
inferred← citeshttps://doi.org/10.1002/ardp.201400116openalex-snapshot
Targeting the TGF‐β Receptor with Kinase Inhibitors for Scleroderma Therapy
inferred← citeshttps://doi.org/10.1002/cbf.3382openalex-snapshot
An in vitro study of scarring formation mediated by human Tenon fibroblasts: Effect of Y‐27632, a Rho kinase inhibitor
inferred← citeshttps://doi.org/10.1002/cbin.10265openalex-snapshot
Focal adhesion kinase (FAK) siRNA inhibits human hypertrophic scar by suppressing integrin α, TGF‐β and α‐SMA
inferred← citeshttps://doi.org/10.1002/jcb.21441openalex-snapshot
Pod1 induces myofibroblast differentiation in mesenchymal progenitor cells from mouse kidney
inferred← citeshttps://doi.org/10.1002/jcp.21345openalex-snapshot
Reversal of myofibroblasts by amniotic membrane stromal extract
inferred← citeshttps://doi.org/10.1002/jcp.25879openalex-snapshot
TGFβ signaling and the control of myofibroblast differentiation: Implications for chronic inflammatory disorders
inferred← citeshttps://doi.org/10.1002/jcp.28011openalex-snapshot
The Smad2/3/4 complex binds miR‐139 promoter to modulate TGFβ‐induced proliferation and activation of human Tenon's capsule fibroblasts through the Wnt pathway
inferred← citeshttps://doi.org/10.1002/path.2973openalex-snapshot
Overexpression of the Flii gene increases dermal–epidermal blistering in an autoimmune ColVII mouse model of epidermolysis bullosa acquisita
inferred← citeshttps://doi.org/10.1007/978-3-319-57613-8_3openalex-snapshot
Properties and Immune Function of Cardiac Fibroblasts
inferred← citeshttps://doi.org/10.1007/s00011-011-0405-7openalex-snapshot
The p38 mitogen-activated protein kinases modulate endothelial cell survival and tissue repair
inferred← citeshttps://doi.org/10.1007/s00417-014-2872-3openalex-snapshot
Evaluation of filtering blebs exhibiting transconjunctival oozing using anterior segment optical coherence tomography
inferred← citeshttps://doi.org/10.1007/s11010-008-9801-xopenalex-snapshot
Osteoblastic MG-63 cell differentiation, contraction, and mRNA expression in stress-relaxed 3D collagen I gels
inferred← citeshttps://doi.org/10.1007/s11033-009-9645-9openalex-snapshot
Effects of ROCK inhibitor, Y-27632, on adhesion and mobility in esophageal squamous cell cancer cells
inferred← citeshttps://doi.org/10.1007/s12017-021-08662-2openalex-snapshot
Long Noncoding RNA LINC01518 Modulates Proliferation and Migration in TGF-β1-Treated Human Tenon Capsule Fibroblast Cells Through the Regulation of hsa-miR-216b-5p
inferred← citeshttps://doi.org/10.1007/s43450-022-00334-xopenalex-snapshot
Liensinine, an Isoquinoline-Type Alkaloid in Lotus Seeds, Suppressed TGF-beta1-Induced Proliferation and Migration in Human Tenon Capsule Fibroblast Cells Through MAP3K7 Gene
inferred← citeshttps://doi.org/10.1016/b978-0-7020-2983-7.00028-0openalex-snapshot
Wound-healing responses to glaucoma surgery
inferred← citeshttps://doi.org/10.1016/b978-012370585-3.50017-0openalex-snapshot
Tissue Repair and Regeneration
inferred← citeshttps://doi.org/10.1016/j.ajpath.2014.07.022openalex-snapshot
Protein Phosphatase Magnesium Dependent 1A Governs the Wound Healing–Inflammation–Angiogenesis Cross Talk on Injury
inferred← citeshttps://doi.org/10.1016/j.apsb.2020.09.001openalex-snapshot
Artemisinin and artemisinin derivatives as anti-fibrotic therapeutics
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.01.052openalex-snapshot
The selective cysteinyl leukotriene receptor 1 (CysLT1R) antagonist montelukast regulates extracellular matrix remodeling
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116130openalex-snapshot
The involvement of the Wnt/β-catenin signaling cascade in fibrosis progression and its therapeutic targeting by relaxin
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111192openalex-snapshot
Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
inferred← citeshttps://doi.org/10.1016/j.devcel.2012.08.017openalex-snapshot
A TRPC6-Dependent Pathway for Myofibroblast Transdifferentiation and Wound Healing In Vivo
inferred← citeshttps://doi.org/10.1016/j.ejphar.2016.02.059openalex-snapshot
Paclitaxel inhibits cell proliferation and collagen lattice contraction via TGF-β signaling pathway in human tenon's fibroblasts in vitro
inferred← citeshttps://doi.org/10.1016/j.exer.2020.108119openalex-snapshot
Epigallocatechin-3-gallate (EGCG) inhibits myofibroblast transformation of human Tenon's fibroblasts
inferred← citeshttps://doi.org/10.1016/j.jcrs.2006.08.035openalex-snapshot
Seven-year follow-up of combined cataract extraction and viscocanalostomy
inferred← citeshttps://doi.org/10.1016/j.jdermsci.2012.09.012openalex-snapshot
Knockdown of electron transfer flavoprotein β subunit reduced TGF-β-induced α-SMA mRNA expression but not COL1A1 in fibroblast-populated three-dimensional collagen gel cultures
inferred← citeshttps://doi.org/10.1016/j.jdermsci.2017.08.013openalex-snapshot
FGF2-mediated attenuation of myofibroblast activation is modulated by distinct MAPK signaling pathways in human dermal fibroblasts
inferred← citeshttps://doi.org/10.1016/j.joca.2016.05.014openalex-snapshot
Bone morphogenetic protein 2/SMAD signalling in human ligamentocytes of degenerated and aged anterior cruciate ligaments
inferred← citeshttps://doi.org/10.1016/j.ophtha.2008.06.009openalex-snapshot
Evaluation of Subconjunctival Bevacizumab as an Adjunct to Trabeculectomy
inferred← citeshttps://doi.org/10.1016/j.preteyeres.2007.12.002openalex-snapshot
Fibrotic disorders in the eye: Targets of gene therapy
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2022.155558openalex-snapshot
Suppression of NADPH oxidase 4 inhibits PM2.5-induced cardiac fibrosis through ROS-P38 MAPK pathway
inferred← citeshttps://doi.org/10.1016/j.survophthal.2012.01.008openalex-snapshot
Wound Modulation After Filtration Surgery
inferred← citeshttps://doi.org/10.1016/j.trsl.2011.06.002openalex-snapshot
Gefitinib attenuates transforming growth factor-β1–activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2013.10.019openalex-snapshot
Myofibroblasts: Trust your heart and let fate decide
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2016.05.002openalex-snapshot
Molecular networks underlying myofibroblast fate and fibrosis
inferred← citeshttps://doi.org/10.1016/s0079-6123(08)01117-5openalex-snapshot
Modulation of wound healing during and after glaucoma surgery
inferred← citeshttps://doi.org/10.1038/nrcardio.2014.162openalex-snapshot
Cardiac valve cells and their microenvironment—insights from in vitro studies
inferred← citeshttps://doi.org/10.1038/onc.2013.18openalex-snapshot
CLIC4 regulates TGF-β-dependent myofibroblast differentiation to produce a cancer stroma
inferred← citeshttps://doi.org/10.1038/s41401-020-00587-zopenalex-snapshot
6-Gingerol protects against cardiac remodeling by inhibiting the p38 mitogen-activated protein kinase pathway
inferred← citeshttps://doi.org/10.1038/s41598-017-00845-xopenalex-snapshot
TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma
inferred← citeshttps://doi.org/10.1038/s41598-019-46075-1openalex-snapshot
Macrophages promote a profibrotic phenotype in orbital fibroblasts through increased hyaluronic acid production and cell contractility
inferred← citeshttps://doi.org/10.1038/s41598-024-52359-yopenalex-snapshot
A MEK inhibitor arrests the cell cycle of human conjunctival fibroblasts and improves the outcome of glaucoma filtration surgery
inferred← citeshttps://doi.org/10.1038/srep25785openalex-snapshot
Identification of P-Rex1 as an anti-inflammatory and anti-fibrogenic target for pulmonary fibrosis
inferred← citeshttps://doi.org/10.1038/srep30872openalex-snapshot
Control of fibrotic changes through the synergistic effects of anti-fibronectin antibody and an RGDS-tagged form of the same antibody
inferred← citeshttps://doi.org/10.1042/bsr20130091openalex-snapshot
Fibroblast-to-myofibroblast switch is mediated by NAD(P)H oxidase generated reactive oxygen species
inferred← citeshttps://doi.org/10.1074/jbc.m110.127183openalex-snapshot
Hyaluronan Synthesis Mediates the Fibrotic Response of Keratocytes to Transforming Growth Factor β
inferred← citeshttps://doi.org/10.1074/jbc.m110.128959openalex-snapshot
Tgfβ Signaling Directly Induces Arf Promoter Remodeling by a Mechanism Involving Smads 2/3 and p38 MAPK
inferred← citeshttps://doi.org/10.1074/jbc.m113.504290openalex-snapshot
Akt1 Mediates α-Smooth Muscle Actin Expression and Myofibroblast Differentiation via Myocardin and Serum Response Factor
inferred← citeshttps://doi.org/10.1074/jbc.m114.558130openalex-snapshot
Prostaglandin E2 Inhibits α-Smooth Muscle Actin Transcription during Myofibroblast Differentiation via Distinct Mechanisms of Modulation of Serum Response Factor and Myocardin-related Transcription Factor-A
inferred← citeshttps://doi.org/10.1074/jbc.m803645200openalex-snapshot
Focal Adhesion Kinase (FAK)-related Non-kinase Inhibits Myofibroblast Differentiation through Differential MAPK Activation in a FAK-dependent Manner
inferred← citeshttps://doi.org/10.1080/02713683.2022.2039204openalex-snapshot
Glaucoma – ‘A Stiff Eye in a Stiff Body’
inferred← citeshttps://doi.org/10.1080/08977194.2023.2215335openalex-snapshot
Dynamics of transforming growth factor β signaling and therapeutic efficacy
inferred← citeshttps://doi.org/10.1080/15384101.2016.1170261openalex-snapshot
Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma
inferred← citeshttps://doi.org/10.1089/jop.2018.0120openalex-snapshot
Inhibition of LPA 1 Signaling Impedes Conversion of Human Tenon's Fibroblasts into Myofibroblasts Via Suppressing TGF-β/Smad2/3 Signaling
inferred← citeshttps://doi.org/10.1093/carcin/bgn077openalex-snapshot
A novel role of thrombospondin-1 in cervical carcinogenesis: inhibit stroma reaction by inhibiting activated fibroblasts from invading cancer
inferred← citeshttps://doi.org/10.1093/cvr/cvq224openalex-snapshot
Role of myofibroblasts in vascular remodelling: focus on restenosis and aneurysm
inferred← citeshttps://doi.org/10.1093/cvr/cvu062openalex-snapshot
Crosstalk between fibroblasts and inflammatory cells
inferred← citeshttps://doi.org/10.1096/fj.14-254623openalex-snapshot
Roles of transforming growth factor‐β1 and OB‐cadherin in porcine cardiac valve myofibroblast differentiation
inferred← citeshttps://doi.org/10.1097/ijg.0000000000000201openalex-snapshot
A p38 MAPK Inhibitor Improves Outcome After Glaucoma Filtration Surgery
inferred← citeshttps://doi.org/10.1101/2023.09.26.559527openalex-snapshot
Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts
inferred← citeshttps://doi.org/10.1111/exd.12854openalex-snapshot
The role of aldo‐keto reductase 1 C 3 ( AKR 1 C 3)‐mediated prostaglandin D 2 ( PGD 2) metabolism in keloids
inferred← citeshttps://doi.org/10.1111/sji.12298openalex-snapshot
Immunopathogenesis of Myocarditis: The Interplay Between Cardiac Fibroblast Cells, Dendritic Cells, Macrophages and CD 4+T Cells
inferred← citeshttps://doi.org/10.1111/vop.12485openalex-snapshot
Altering equine corneal fibroblast differentiation through Smad gene transfer
inferred← citeshttps://doi.org/10.1111/wrr.12390openalex-snapshot
A cell‐based screening assay to identify pharmaceutical compounds that enhance the regenerative quality of corneal repair
inferred← citeshttps://doi.org/10.1128/iai.02158-14openalex-snapshot
Endotoxin-Induced Endothelial Fibrosis Is Dependent on Expression of Transforming Growth Factors β1 and β2
inferred← citeshttps://doi.org/10.1152/ajpendo.00015.2010openalex-snapshot
Enhanced transforming growth factor-β signaling and fibrogenesis in ovine fetal skeletal muscle of obese dams at late gestation
inferred← citeshttps://doi.org/10.1152/ajpendo.00434.2010openalex-snapshot
Maternal obesity induces fibrosis in fetal myocardium of sheep
inferred← citeshttps://doi.org/10.1152/ajplung.90462.2008openalex-snapshot
MMP dependence of fibroblast contraction and collagen production induced by human mast cell activation in a three-dimensional collagen lattice
inferred← citeshttps://doi.org/10.1152/ajprenal.00010.2007openalex-snapshot
MKK3-p38 signaling promotes apoptosis and the early inflammatory response in the obstructed mouse kidney
inferred← citeshttps://doi.org/10.1159/000246571openalex-snapshot
Future Target Molecules in Antiglaucoma Therapy: TGF-β May Have a Role to Play
inferred← citeshttps://doi.org/10.1159/000341470openalex-snapshot
Microarray Analysis of Dupuytrens Disease Cells: The Profibrogenic Role of the TGF-� Inducible p38 MAPK Pathway
inferred← citeshttps://doi.org/10.1159/000345525openalex-snapshot
Differential Roles of JNK, ERK1/2, and p38 Mitogen-Activated Protein Kinases on Endothelial Cell Tissue Repair Functions in Response to Tumor Necrosis Factor-α
inferred← citeshttps://doi.org/10.1161/circulationaha.116.026238openalex-snapshot
Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis
inferred← citeshttps://doi.org/10.1165/rcmb.2016-0374ocopenalex-snapshot
p38 MAPK Inhibition Improves Heart Function in Pressure-Loaded Right Ventricular Hypertrophy
inferred← citeshttps://doi.org/10.1167/iovs.06-0118openalex-snapshot
Contractility as a Prerequisite for TGF-β–Induced Myofibroblast Transdifferentiation in Human Tenon Fibroblasts
inferred← citeshttps://doi.org/10.1167/iovs.06-0968openalex-snapshot
Expression and Function of Toll-like Receptor-3 and -9 in Human Corneal Myofibroblasts
inferred← citeshttps://doi.org/10.1167/iovs.07-0878openalex-snapshot
Potential Role of Rho-Associated Protein Kinase Inhibitor Y-27632 in Glaucoma Filtration Surgery
inferred← citeshttps://doi.org/10.1167/iovs.07-1610openalex-snapshot
Lovastatin Inhibits TGF-β–Induced Myofibroblast Transdifferentiation in Human Tenon Fibroblasts
inferred← citeshttps://doi.org/10.1167/iovs.08-1675openalex-snapshot
SB-431542 Inhibition of Scar Formation after Filtration Surgery and Its Potential Mechanism
inferred← citeshttps://doi.org/10.1167/iovs.08-2815openalex-snapshot
Effects of Pirfenidone on Proliferation, Migration, and Collagen Contraction of Human Tenon’s Fibroblasts In Vitro
inferred← citeshttps://doi.org/10.1167/iovs.10-6679openalex-snapshot
Extracellular Matrix Elasticity Modulates TGF-β–Induced p38 Activation and Myofibroblast Transdifferentiation in Human Tenon Fibroblasts
inferred← citeshttps://doi.org/10.1167/iovs.11-8491openalex-snapshot
Transduction of PTEN Proteins Using the Tat Domain Modulates TGF-β1–Mediated Signaling Pathways and Transdifferentiation in Subconjunctival Fibroblasts
inferred← citeshttps://doi.org/10.1167/iovs.12-10198openalex-snapshot
A Novel Aptamer Targeting TGF-β Receptor II Inhibits Transdifferentiation of Human Tenon's Fibroblasts into Myofibroblast
inferred← citeshttps://doi.org/10.1167/iovs.13-13572openalex-snapshot
Inhibition by All- Trans -Retinoic Acid of Transforming Growth Factor-β–Induced Collagen Gel Contraction Mediated by Human Tenon Fibroblasts
inferred← citeshttps://doi.org/10.1167/iovs.15-17693openalex-snapshot
Activation of Prostaglandin FP and EP2 Receptors Differently Modulates Myofibroblast Transition in a Model of Adult Primary Human Trabecular Meshwork Cells
inferred← citeshttps://doi.org/10.1167/iovs.16-19529openalex-snapshot
Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2–Treated Human Tenon's Fibroblasts
inferred← citeshttps://doi.org/10.1172/jci144336openalex-snapshot
IL-36 in chronic inflammation and fibrosis — bridging the gap?
inferred← citeshttps://doi.org/10.1186/s12891-019-2486-3openalex-snapshot
Investigating the effects of Pirfenidone on TGF-β1 stimulated non-SMAD signaling pathways in Dupuytren’s disease -derived fibroblasts
inferred← citeshttps://doi.org/10.1186/s40001-026-04514-6openalex-snapshot
The relationship between the nasal conjunctival origin of primary pterygium and the position of the medial rectus muscle
inferred← citeshttps://doi.org/10.1272/jnms.79.46openalex-snapshot
Sequential Analysis of Myofibroblast Differentiation and Transforming Growth Factor-β1/Smad Pathway Activation in Murine Pulmonary Fibrosis
inferred← citeshttps://doi.org/10.1371/journal.pone.0105796openalex-snapshot
Rosiglitazone Inhibits TGF-β 1 Induced Activation of Human Tenon Fibroblasts via p38 Signal Pathway
inferred← citeshttps://doi.org/10.1371/journal.pone.0120724openalex-snapshot
Stromal Expression of Heat-Shock Protein 27 Is Associated with Worse Clinical Outcome in Patients with Colorectal Cancer Lung Metastases
inferred← citeshttps://doi.org/10.1371/journal.pone.0125169openalex-snapshot
Adiponectin Attenuates Lung Fibroblasts Activation and Pulmonary Fibrosis Induced by Paraquat
inferred← citeshttps://doi.org/10.1371/journal.pone.0153968openalex-snapshot
Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-β Signaling Pathway
inferred← citeshttps://doi.org/10.18632/oncotarget.22737openalex-snapshot
Interaction of macrophages with apoptotic cells inhibits transdifferentiation and invasion of lung fibroblasts
inferred← citeshttps://doi.org/10.18632/oncotarget.6703openalex-snapshot
Sphingosine kinase 1 is required for TGF-β mediated fibroblast-to-myofibroblast differentiation in ovarian cancer
inferred← citeshttps://doi.org/10.18632/oncotarget.9667openalex-snapshot
Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2
inferred← citeshttps://doi.org/10.2174/0113816128308622240709102830openalex-snapshot
Huangqi Guizhi Wuwu Decoction Improves Inflammatory Factor Levels in Chemotherapy-induced Peripheral Neuropathy by Regulating the Arachidonic Acid Metabolic Pathway
inferred← citeshttps://doi.org/10.3341/kjo.2012.26.1.45openalex-snapshot
The Role of Focal Adhesion Kinase in the TGF-β-Induced Myofibroblast Transdifferentiation of Human Tenon's Fibroblasts
inferred← citeshttps://doi.org/10.33549/physiolres.933092openalex-snapshot
The Role of Cytokines TGF-β1 and FGF-1 in the Expression of Characteristic Markers of Rat Liver Myofibroblasts Cultured in Three-Dimensional Collagen Gel
inferred← citeshttps://doi.org/10.3389/fimmu.2018.02452openalex-snapshot
Unraveling SSc Pathophysiology; The Myofibroblast
inferred← citeshttps://doi.org/10.3389/fphar.2021.644886openalex-snapshot
Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization
inferred← citeshttps://doi.org/10.3389/fphar.2021.696635openalex-snapshot
Ivabradine Ameliorates Cardiac Diastolic Dysfunction in Diabetic Mice Independent of Heart Rate Reduction
inferred← citeshttps://doi.org/10.3390/biomedicines11030657openalex-snapshot
Novel Therapies for the Prevention of Fibrosis in Glaucoma Filtration Surgery
inferred← citeshttps://doi.org/10.3390/cells10071572openalex-snapshot
Inhibition of CREB-CBP Signaling Improves Fibroblast Plasticity for Direct Cardiac Reprogramming
inferred← citeshttps://doi.org/10.3390/cells10082131openalex-snapshot
Metformin and Glaucoma—Review of Anti-Fibrotic Processes and Bioenergetics
inferred← citeshttps://doi.org/10.3390/ijms20081972openalex-snapshot
Migrating Myofibroblastic Iliotibial Band-Derived Fibroblasts Represent a Promising Cell Source for Ligament Reconstruction
inferred← citeshttps://doi.org/10.3390/ijms20194670openalex-snapshot
Activation of the Sphingosine 1 Phosphate–Rho Pathway in Pterygium and in Ultraviolet-Irradiated Normal Conjunctiva
inferred← citeshttps://doi.org/10.3390/ijms222111748openalex-snapshot
Understanding Drivers of Ocular Fibrosis: Current and Future Therapeutic Perspectives
inferred← citeshttps://doi.org/10.3390/ijms222312790openalex-snapshot
SB203580—A Potent p38 MAPK Inhibitor Reduces the Profibrotic Bronchial Fibroblasts Transition Associated with Asthma
inferred← citeshttps://doi.org/10.3892/ijmm.2018.3949openalex-snapshot
Crosstalk between mitogen-activated protein kinase inhibitors and transforming growth factor-β signaling results in variable activation of human dermal fibroblasts
inferred← citeshttps://doi.org/10.3892/ijo.2013.2100openalex-snapshot
Rho/Rho-associated kinase pathway in glaucoma
inferred← citeshttps://doi.org/10.3892/mmr.2018.9673openalex-snapshot
MEK inhibition prevents TGF‑β1‑induced myofibroblast transdifferentiation in human tenon fibroblasts
inferred← citeshttps://doi.org/10.4049/jimmunol.181.7.5001openalex-snapshot
Mast Cells Promote Airway Smooth Muscle Cell Differentiation via Autocrine Up-Regulation of TGF-β1
inferred← citeshttps://doi.org/10.7150/ijbs.6.350openalex-snapshot
Differential transcriptional analysis between red and white skeletal muscle of Chinese Meishan pigs
inferred← citeshttps://doi.org/10.7554/elife.91876openalex-snapshot
Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts
inferred← citeshttps://doi.org/10.7554/elife.91876.1openalex-snapshot
Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts
inferred← citeshttps://doi.org/10.7554/elife.91876.2openalex-snapshot
Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts
inferred← citeshttps://doi.org/10.7554/elife.91876.3openalex-snapshot
Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts
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