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Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1097-0142(19980815)83:4<797::aid-cncr25>3.0.co;2-mopenalex-snapshot
Trends in the safety of high dose bolus interleukin-2 administration in patients with metastatic cancer
inferredcites →https://doi.org/10.1002/eji.1830250831openalex-snapshot
Tumor cells cotransfected with interleukin‐7 and B7.1 genes induce CD25 and CD28 on tumor‐infiltrating T lymphocytes and are strong vaccines
inferredcites →https://doi.org/10.1016/j.immuni.2004.06.015openalex-snapshot
Immunodominance in TCD8+ Responses to Viruses
inferredcites →https://doi.org/10.1016/s0264-410x(98)00271-0openalex-snapshot
IL-15 expression plasmid enhances cell-mediated immunity induced by an HIV-1 DNA vaccine
inferredcites →https://doi.org/10.1016/s1074-7613(00)80092-8openalex-snapshot
The Peptide Ligands Mediating Positive Selection in the Thymus Control T Cell Survival and Homeostatic Proliferation in the Periphery
inferredcites →https://doi.org/10.1016/s1074-7613(00)80093-xopenalex-snapshot
Low-Affinity Ligands for the TCR Drive Proliferation of Mature CD8+ T Cells in Lymphopenic Hosts
inferredcites →https://doi.org/10.1016/s1074-7613(00)80461-6openalex-snapshot
The Duration of Antigenic Stimulation Determines the Fate of Naive and Effector T Cells
inferredcites →https://doi.org/10.1016/s1074-7613(00)80564-6openalex-snapshot
Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15
inferredcites →https://doi.org/10.1016/s1074-7613(02)00429-6openalex-snapshot
IL-15Rα Recycles and Presents IL-15 In trans to Neighboring Cells
inferredcites →https://doi.org/10.1038/21208openalex-snapshot
Modelling T-cell memory by genetic marking of memory T cells in vivo
inferredcites →https://doi.org/10.1038/369652a0openalex-snapshot
Virus-specific CD8+ T-cell memory determined by clonal burst size
inferredcites →https://doi.org/10.1038/80868openalex-snapshot
Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo
inferredcites →https://doi.org/10.1038/83381openalex-snapshot
Increased production of IL-7 accompanies HIV-1–mediated T-cell depletion: implications for T-cell homeostasis
inferredcites →https://doi.org/10.1038/87720openalex-snapshot
Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells
inferredcites →https://doi.org/10.1038/87730openalex-snapshot
Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation
inferredcites →https://doi.org/10.1038/ni0104-7openalex-snapshot
Dendritic cells: a journey from laboratory to clinic
inferredcites →https://doi.org/10.1038/ni1009openalex-snapshot
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
inferredcites →https://doi.org/10.1038/ni908openalex-snapshot
T cell fitness determined by signal strength
inferredcites →https://doi.org/10.1038/nm1100openalex-snapshot
Cancer immunotherapy: moving beyond current vaccines
inferredcites →https://doi.org/10.1038/nm866openalex-snapshot
Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo
inferredcites →https://doi.org/10.1038/nri778openalex-snapshot
Effector and memory T-cell differentiation: implications for vaccine development
inferredcites →https://doi.org/10.1038/sj.bmt.1701655openalex-snapshot
Serum levels of IL-7 in bone marrow transplant recipients: relationship to clinical characteristics and lymphocyte count
inferredcites →https://doi.org/10.1073/pnas.0630592100openalex-snapshot
Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity
inferredcites →https://doi.org/10.1073/pnas.161126098openalex-snapshot
IL-7 is critical for homeostatic proliferation and survival of naïve T cells
inferredcites →https://doi.org/10.1073/pnas.200363097openalex-snapshot
IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice
inferredcites →https://doi.org/10.1073/pnas.92.12.5491openalex-snapshot
Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division.
inferredcites →https://doi.org/10.1084/jem.20020066openalex-snapshot
Interleukin (IL)-15 and IL-7 Jointly Regulate Homeostatic Proliferation of Memory Phenotype CD8+ Cells but Are Not Required for Memory Phenotype CD4+ Cells
inferredcites →https://doi.org/10.1084/jem.20020067openalex-snapshot
Overexpression of Interleukin (IL)-7 Leads to IL-15–independent Generation of Memory Phenotype CD8+ T Cells
inferredcites →https://doi.org/10.1089/hum.1994.5.12-1457openalex-snapshot
Consequences of Stable Transduction and Antigen-Inducible Expression of the Human Interleukin-7 Gene on Tetanus-Toxoid-Specific T Cells
inferredcites →https://doi.org/10.1097/00002371-200409000-00001openalex-snapshot
Escape from Immune Surveillance Does Not Result in Tolerance to Tumor-Associated Antigens
inferredcites →https://doi.org/10.1097/00043426-199211000-00005openalex-snapshot
A Phase I Study of Interleukin-2 in Children with Cancer
inferredcites →https://doi.org/10.1126/science.1070441openalex-snapshot
Diversity Considerations in HIV-1 Vaccine Selection
inferredcites →https://doi.org/10.1126/science.1076514openalex-snapshot
Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes
inferredcites →https://doi.org/10.1126/science.283.5408.1745openalex-snapshot
Linear Differentiation of Cytotoxic Effectors into Memory T Lymphocytes
inferredcites →https://doi.org/10.1126/science.288.5466.675openalex-snapshot
Control of Homeostasis of CD8 + Memory T Cells by Opposing Cytokines
inferredcites →https://doi.org/10.1128/cdli.7.5.751-758.2000openalex-snapshot
Interleukin 7 Can Enhance Antigen-Specific Cytotoxic-T-Lymphocyte and/or Th2-Type Immune Responses In Vivo
inferredcites →https://doi.org/10.1128/iai.68.5.2962-2970.2000openalex-snapshot
Interleukin-7 or Interleukin-15 Enhances Survival ofMycobacterium tuberculosis-Infected Mice
inferredcites →https://doi.org/10.1128/jvi.77.8.4911-4927.2003openalex-snapshot
Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment
inferredcites →https://doi.org/10.1146/annurev.immunol.21.120601.141045openalex-snapshot
On Natural and Artificial Vaccinations
inferredcites →https://doi.org/10.1172/jci200422674openalex-snapshot
Progress on new vaccine strategies against chronic viral infections
inferredcites →https://doi.org/10.1172/jci22674openalex-snapshot
Progress on new vaccine strategies against chronic viral infections
inferredcites →https://doi.org/10.1182/blood-2002-04-1082openalex-snapshot
Interleukin 7 worsens graft-versus-host disease
inferredcites →https://doi.org/10.1182/blood-2002-07-2297openalex-snapshot
IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates
inferredcites →https://doi.org/10.1182/blood-2002-08-2671openalex-snapshot
Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys
inferredcites →https://doi.org/10.1182/blood.v97.10.2983openalex-snapshot
A potential role for interleukin-7 in T-cell homeostasis
inferredcites →https://doi.org/10.1182/blood.v97.6.1525openalex-snapshot
Interleukin-7 restores immunity in athymic T-cell–depleted hosts
inferredcites →https://doi.org/10.4049/jimmunol.156.12.4609openalex-snapshot
Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing
inferredcites →https://doi.org/10.4049/jimmunol.161.11.5909openalex-snapshot
IL-7-Dependent Extrathymic Expansion of CD45RA+ T Cells Enables Preservation of a Naive Repertoire
inferredcites →https://doi.org/10.4049/jimmunol.162.8.4502openalex-snapshot
Biochemical and Immunogenetic Analysis of an Immunodominant Peptide (B6dom1) Encoded by the Classical H7 Minor Histocompatibility Locus
inferredcites →https://doi.org/10.4049/jimmunol.163.8.4503openalex-snapshot
IL-15 Prolongs the Duration of CD8+ T Cell-Mediated Immunity in Mice Infected with a Vaccine Strain of Toxoplasma gondii
inferredcites →https://doi.org/10.4049/jimmunol.166.5.3019openalex-snapshot
IL-7 Administration Alters the CD4:CD8 Ratio, Increases T Cell Numbers, and Increases T Cell Function in the Absence of Activation
inferredcites →https://doi.org/10.4049/jimmunol.168.3.1198openalex-snapshot
Overexpression of IL-15 In Vivo Increases Antigen-Driven Memory CD8+ T Cells Following a Microbe Exposure
inferredcites →https://doi.org/10.4049/jimmunol.169.9.4928openalex-snapshot
Systemic Administration of IL-15 Augments the Antigen-Specific Primary CD8+ T Cell Response Following Vaccination with Peptide-Pulsed Dendritic Cells
inferredcites →https://doi.org/10.4049/jimmunol.170.10.5018openalex-snapshot
IL-15 Promotes the Survival of Naive and Memory Phenotype CD8+ T Cells
inferredcites →https://doi.org/10.4049/jimmunol.171.8.3928openalex-snapshot
Different Dynamics of CD4+ and CD8+ T Cell Responses During and After Acute Lymphocytic Choriomeningitis Virus Infection
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4166327openalex-extracted
The CIt Protocol: A Blueprint to Potentiate the Immunogenicity of Immunoproteasome-Reprogrammed Mesenchymal Stromal Cells
inferred← citeshttps://doi.org/10.1002/9781119000822.hfcm068.pub2openalex-snapshot
Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1002/9781119000822.hfcm069.pub2openalex-snapshot
Cancer Gene Therapy
inferred← citeshttps://doi.org/10.1002/bit.24431openalex-snapshot
Microparticle delivery of Interleukin‐7 to boost T‐cell proliferation and survival
inferred← citeshttps://doi.org/10.1002/dvg.20497openalex-snapshot
IL7‐hCD25 and IL7‐Cre BAC transgenic mouse lines: New tools for analysis of IL‐7 expressing cells
inferred← citeshttps://doi.org/10.1002/eji.200939271openalex-snapshot
Marked enhancement of antigen‐specific T‐cell responses by IL‐7‐fused nonlytic, but not lytic, Fc as a genetic adjuvant
inferred← citeshttps://doi.org/10.1002/eji.201040603openalex-snapshot
Tumor immune therapy: Lessons from infection and implications for cancer – Can IL‐7 help overcome immune inhibitory networks?
inferred← citeshttps://doi.org/10.1007/978-0-387-72005-0_35openalex-snapshot
Interleukin-7 Immunotherapy
inferred← citeshttps://doi.org/10.1007/978-0-387-76842-7_10openalex-snapshot
The Efficacy of Vaccines to Prevent Infectious Diseases in the Elderly
inferred← citeshttps://doi.org/10.1007/978-1-4020-9063-9_72openalex-snapshot
Interleukin -7 and Immunorejuvenation
inferred← citeshttps://doi.org/10.1007/978-1-60761-980-2_19openalex-snapshot
Allogeneic and Autologous Transplantation Therapy of Cancer: Converging Themes
inferred← citeshttps://doi.org/10.1007/978-1-60761-980-2_9openalex-snapshot
Mechanisms and Implications of Immunodominance in CD8+ T-Cell Responses
inferred← citeshttps://doi.org/10.1007/978-1-62703-290-2_9openalex-snapshot
Homeostatic Proliferation of Mature T Cells
inferred← citeshttps://doi.org/10.1007/978-3-0346-0219-8_9openalex-snapshot
Immunosenescence and the 3Rs: Restoration, Replacement and Reprogramming
inferred← citeshttps://doi.org/10.1007/978-4-431-56027-2_3openalex-snapshot
Strategies for Thymic Regeneration: Recent Advances Towards Clinical Therapy
inferred← citeshttps://doi.org/10.1007/978-90-481-3999-6_15openalex-snapshot
Maintenance and Restoration of Immune System Function
inferred← citeshttps://doi.org/10.1007/978-981-13-1699-9_8openalex-snapshot
Immune Modulation and Its Role in Antiaging
inferred← citeshttps://doi.org/10.1007/978-981-99-4657-0_13openalex-snapshot
Prognostic and Diagnostic Significance of Chemokines and Cytokines in Cancer
inferred← citeshttps://doi.org/10.1007/s00262-008-0638-7openalex-snapshot
Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches
inferred← citeshttps://doi.org/10.1007/s00262-009-0666-yopenalex-snapshot
Incubation of antigen-sensitized T lymphocytes activated with bryostatin 1 + ionomycin in IL-7 + IL-15 increases yield of cells capable of inducing regression of melanoma metastases compared to culture in IL-2
inferred← citeshttps://doi.org/10.1007/s00262-011-1020-8openalex-snapshot
Exploitation of differential homeostatic proliferation of T-cell subsets following chemotherapy to enhance the efficacy of vaccine-mediated antitumor responses
inferred← citeshttps://doi.org/10.1007/s00262-012-1215-7openalex-snapshot
IL-15 augments antitumoral activity of an ErbB2/HER2 cancer vaccine targeted to professional antigen-presenting cells
inferred← citeshttps://doi.org/10.1007/s00262-016-1808-7openalex-snapshot
Requirement of interleukin 7 signaling for anti-tumor immune response under lymphopenic conditions in a murine lung carcinoma model
inferred← citeshttps://doi.org/10.1007/s10549-008-0024-3openalex-snapshot
Radiofrequency thermal ablation of breast tumors combined with intralesional administration of IL-7 and IL-15 augments anti-tumor immune responses and inhibits tumor development and metastasis
inferred← citeshttps://doi.org/10.1007/s10549-009-0573-0openalex-snapshot
IL-7 + IL-15 are superior to IL-2 for the ex vivo expansion of 4T1 mammary carcinoma-specific T cells with greater efficacy against tumors in vivo
inferred← citeshttps://doi.org/10.1007/s11523-012-0210-4openalex-snapshot
Interleukin-7 and immune reconstitution in cancer patients: a new paradigm for dramatically increasing overall survival
inferred← citeshttps://doi.org/10.1007/s12026-008-8027-zopenalex-snapshot
Intrinsic and extrinsic control of effector T cell survival and memory T cell development
inferred← citeshttps://doi.org/10.1016/b978-0-12-374279-7.17019-5openalex-snapshot
Vaccines and Their Role in CD8 T Cell-Mediated Antitumor Immunity
inferred← citeshttps://doi.org/10.1016/b978-0-12-822569-1.00020-2openalex-snapshot
Vaccination in old age: Challenges and promises
inferred← citeshttps://doi.org/10.1016/b978-1-4557-5414-4.00047-4openalex-snapshot
10.1016/b978-1-4557-5414-4.00047-4
inferred← citeshttps://doi.org/10.1016/bs.mcb.2023.04.002openalex-snapshot
Adoptive immunotherapy with cells from tumor-draining lymph nodes activated and expanded in vitro
inferred← citeshttps://doi.org/10.1016/j.bbmt.2010.12.712openalex-snapshot
Extracorporeal Photopheresis Attenuates Murine Graft-versus-Host Disease via Bone Marrow–Derived Interleukin-10 and Preserves Responses to Dendritic Cell Vaccination
inferred← citeshttps://doi.org/10.1016/j.bbmt.2013.10.009openalex-snapshot
Minor Antigen Distribution Predicts Site-Specific Graft-versus-Tumor Activity of Adoptively Transferred, Minor Antigen-Specific CD8 T Cells
inferred← citeshttps://doi.org/10.1016/j.beha.2005.11.004openalex-snapshot
Autologous immune strategies to reduce the risk of leukemic relapse: Consideration for IL-15
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2016.08.043openalex-snapshot
Nanostructured recombinant cytokines: A highly stable alternative to short-lived prophylactics
inferred← citeshttps://doi.org/10.1016/j.clim.2005.08.013openalex-snapshot
Adoptive immunotherapy: New ways to skin the cat?
inferred← citeshttps://doi.org/10.1016/j.clim.2007.04.003openalex-snapshot
Maximizing CD8+ T cell responses elicited by peptide vaccines containing CpG oligodeoxynucleotides
inferred← citeshttps://doi.org/10.1016/j.coi.2006.05.016openalex-snapshot
Progress in tuberculosis vaccine development
inferred← citeshttps://doi.org/10.1016/j.coi.2007.04.015openalex-snapshot
Cytokines and T-cell homeostasis
inferred← citeshttps://doi.org/10.1016/j.cyto.2009.09.008openalex-snapshot
Regulation of memory T cells by γc cytokines
inferred← citeshttps://doi.org/10.1016/j.cyto.2015.11.013openalex-snapshot
Regulation of effector and memory CD8+ T cell function by inflammatory cytokines
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2007.01.016openalex-snapshot
The relevance of cytokines for development of protective immunity and rational design of vaccines
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2014.07.012openalex-snapshot
Exploiting differential expression of the IL-7 receptor on memory T cells to modulate immune responses
inferred← citeshttps://doi.org/10.1016/j.exger.2008.04.014openalex-snapshot
Reversal of age-associated thymic atrophy: Treatments, delivery, and side effects
inferred← citeshttps://doi.org/10.1016/j.exger.2021.111454openalex-snapshot
Exercise training partially rescues impaired mucosal associated invariant t-cell mobilization in breast cancer survivors compared to healthy older women
inferred← citeshttps://doi.org/10.1016/j.exppara.2015.12.013openalex-snapshot
Co-administration of interleukins 7 and 15 with DNA vaccine improves protective immunity against Toxoplasma gondii
inferred← citeshttps://doi.org/10.1016/j.imlet.2006.11.006openalex-snapshot
Common γ chain cytokines: Dissidence in the details
inferred← citeshttps://doi.org/10.1016/j.imlet.2009.12.019openalex-snapshot
IL-7, but not thymic stromal lymphopoietin (TSLP), during priming enhances the generation of memory CD4+ T cells
inferred← citeshttps://doi.org/10.1016/j.imlet.2013.12.019openalex-snapshot
IL-7 inhibits tumor growth by promoting T cell-mediated antitumor immunity in Meth A model
inferred← citeshttps://doi.org/10.1016/j.immuni.2007.08.007openalex-snapshot
Heterogeneity and Cell-Fate Decisions in Effector and Memory CD8+ T Cell Differentiation during Viral Infection
inferred← citeshttps://doi.org/10.1016/j.isci.2022.105537openalex-snapshot
The CIt protocol: A blueprint to potentiate the immunogenicity of immunoproteasome-reprogrammed mesenchymal stromal cells
inferred← citeshttps://doi.org/10.1016/j.jaci.2013.05.029openalex-snapshot
Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function
inferred← citeshttps://doi.org/10.1016/j.jaut.2012.01.012openalex-snapshot
IL-7 modulates B cells survival and activation by inducing BAFF and CD70 expression in T cells
inferred← citeshttps://doi.org/10.1016/j.jaut.2013.06.007openalex-snapshot
Interleukin-7: Fuel for the autoimmune attack
inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.10.004openalex-snapshot
Nanomedicine for advanced cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.jcyt.2020.08.006openalex-snapshot
Identification of new cytokine combinations for antigen-specific T-cell therapy products via a high-throughput multi-parameter assay
inferred← citeshttps://doi.org/10.1016/j.jim.2008.01.003openalex-snapshot
Serum-free culture medium and IL-7 costimulation increase the sensitivity of ELISpot detection
inferred← citeshttps://doi.org/10.1016/j.jim.2021.113086openalex-snapshot
Characterization and ex vivo expansion of rare in situ cytokine secreting T cell populations from tumor tissue and blood of oral squamous cell carcinoma patients
inferred← citeshttps://doi.org/10.1016/j.mad.2006.01.016openalex-snapshot
T cell development, ageing and Interleukin-7
inferred← citeshttps://doi.org/10.1016/j.smim.2009.02.002openalex-snapshot
Surviving the crash: Transitioning from effector to memory CD8+ T cell
inferred← citeshttps://doi.org/10.1016/j.smim.2010.02.003openalex-snapshot
Adoptive transfer of unselected or leukemia-reactive T-cells in the treatment of relapse following allogeneic hematopoietic cell transplantation
inferred← citeshttps://doi.org/10.1016/j.tips.2010.05.003openalex-snapshot
Fighting cancers from within: augmenting tumor immunity with cytokine therapy
inferred← citeshttps://doi.org/10.1016/j.vaccine.2005.07.108openalex-snapshot
Regulation of CD4 T cell memory by OX40 (CD134)
inferred← citeshttps://doi.org/10.1016/j.vaccine.2008.03.067openalex-snapshot
IL-15 as memory T-cell adjuvant for topical HIV-1 DermaVir vaccine
inferred← citeshttps://doi.org/10.1016/j.vaccine.2013.04.029openalex-snapshot
Nonlytic Fc-fused IL-7 synergizes with Mtb32 DNA vaccine to enhance antigen-specific T cell responses in a therapeutic model of tuberculosis
inferred← citeshttps://doi.org/10.1016/j.vaccine.2016.10.035openalex-snapshot
Mumps, measles and rubella vaccination in children with PFAPA syndrome
inferred← citeshttps://doi.org/10.1016/j.virol.2006.07.031openalex-snapshot
Decreased number of CD4+ and CD8+ T cells that express the interleukin-7 receptor in blood and tissues of SIV-infected macaques
inferred← citeshttps://doi.org/10.1016/j.virol.2009.01.007openalex-snapshot
Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251
inferred← citeshttps://doi.org/10.1016/j.yasu.2012.03.007openalex-snapshot
How Important is Glycemic Control During Coronary Artery Bypass?
inferred← citeshttps://doi.org/10.1016/j.ymthe.2019.04.001openalex-snapshot
Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma
inferred← citeshttps://doi.org/10.1016/j.ymthe.2022.02.002openalex-snapshot
The generation and application of antigen-specific T cell therapies for cancer and viral-associated disease
inferred← citeshttps://doi.org/10.1016/j.ymthe.2025.04.008openalex-snapshot
DNA-based immunotherapy for cancer: In vivo approaches for recalcitrant targets
inferred← citeshttps://doi.org/10.1038/bcj.2017.29openalex-snapshot
Imatinib mesylate inhibits STAT5 phosphorylation in response to IL-7 and promotes T cell lymphopenia in chronic myelogenous leukemia patients
inferred← citeshttps://doi.org/10.1038/bjc.2012.456openalex-snapshot
Stage-dependent alterations of the serum cytokine pattern in colorectal carcinoma
inferred← citeshttps://doi.org/10.1038/gene.2014.33openalex-snapshot
IL-12 is required for mTOR regulation of memory CTLs during viral infection
inferred← citeshttps://doi.org/10.1038/gt.2014.10openalex-snapshot
Vaccination with tumor cells expressing IL-15 and IL-15Rα inhibits murine breast and prostate cancer
inferred← citeshttps://doi.org/10.1038/icb.2008.30openalex-snapshot
Enhancing T cell memory: IL‐7 as an adjuvant to boost memory T‐cell generation
inferred← citeshttps://doi.org/10.1038/icb.2010.25openalex-snapshot
Immunogenicity and protective efficacy of mycobacterial DNA vaccines incorporating plasmid‐encoded cytokines against Mycobacterium bovis
inferred← citeshttps://doi.org/10.1038/mt.2012.130openalex-snapshot
Rapidly Generated Multivirus-specific Cytotoxic T Lymphocytes for the Prophylaxis and Treatment of Viral Infections
inferred← citeshttps://doi.org/10.1038/mt.2012.265openalex-snapshot
HDAC Inhibition Suppresses Primary Immune Responses, Enhances Secondary Immune Responses, and Abrogates Autoimmunity During Tumor Immunotherapy
inferred← citeshttps://doi.org/10.1038/ncomms6150openalex-snapshot
NK1.1+ CD8+ T cells escape TGF-β control and contribute to early microbial pathogen response
inferred← citeshttps://doi.org/10.1038/ni.1695openalex-snapshot
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells
inferred← citeshttps://doi.org/10.1038/ni.2018openalex-snapshot
Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells
inferred← citeshttps://doi.org/10.1038/nm.1953openalex-snapshot
Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies
inferred← citeshttps://doi.org/10.1038/nm1312openalex-snapshot
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells
inferred← citeshttps://doi.org/10.1038/nri1806openalex-snapshot
Regulatory T cells, tumour immunity and immunotherapy
inferred← citeshttps://doi.org/10.1038/nri2970openalex-snapshot
Harnessing the biology of IL-7 for therapeutic application
inferred← citeshttps://doi.org/10.1038/s41467-023-40959-7openalex-snapshot
Let-7 enhances murine anti-tumor CD8 T cell responses by promoting memory and antagonizing terminal differentiation
inferred← citeshttps://doi.org/10.1038/s41598-017-12488-zopenalex-snapshot
Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells
inferred← citeshttps://doi.org/10.1038/s41598-021-84270-1openalex-snapshot
Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model
inferred← citeshttps://doi.org/10.1038/s44319-024-00191-wopenalex-snapshot
Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity
inferred← citeshttps://doi.org/10.1038/srep32351openalex-snapshot
Forced co-expression of IL-21 and IL-7 in whole-cell cancer vaccines promotes antitumor immunity
inferred← citeshttps://doi.org/10.1042/bcj20210313openalex-snapshot
Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation
inferred← citeshttps://doi.org/10.1073/pnas.0610115104openalex-snapshot
The IL-15/IL-15Rα on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells
inferred← citeshttps://doi.org/10.1073/pnas.0705007104openalex-snapshot
Expression of IL-7 receptor α is necessary but not sufficient for the formation of memory CD8 T cells during viral infection
inferred← citeshttps://doi.org/10.1073/pnas.0712135105openalex-snapshot
CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity
inferred← citeshttps://doi.org/10.1080/08830180600992423openalex-snapshot
Roadmap to a Better Therapeutic Tumor Vaccine
inferred← citeshttps://doi.org/10.1080/14712598.2018.1473368openalex-snapshot
Strategies for enhancing adoptive T-cell immunotherapy against solid tumors using engineered cytokine signaling and other modalities
inferred← citeshttps://doi.org/10.1080/14712598.2018.1518422openalex-snapshot
Understanding how combinatorial targeting of TLRs and TNFR family costimulatory members promote enhanced T cell responses
inferred← citeshttps://doi.org/10.1080/15384047.2020.1739952openalex-snapshot
Chimeric cytokine receptor enhancing PSMA-CAR-T cell-mediated prostate cancer regression
inferred← citeshttps://doi.org/10.1080/2162402x.2014.1002720openalex-snapshot
Extending the lifespan and efficacies of immune cells used in adoptive transfer for cancer immunotherapies–A review
inferred← citeshttps://doi.org/10.1080/21645515.2015.1009814openalex-snapshot
Clinically feasible approaches to potentiating cancer cell-based immunotherapies
inferred← citeshttps://doi.org/10.1084/jem.20071681openalex-snapshot
Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets
inferred← citeshttps://doi.org/10.1084/jem.20192203openalex-snapshot
Optimized gene engineering of murine CAR-T cells reveals the beneficial effects of IL-15 coexpression
inferred← citeshttps://doi.org/10.1086/653827openalex-snapshot
Coadministration of Interleukins 7 and 15 with Bacille Calmette‐Guérin Mounts Enduring T Cell Memory Response againstMycobacterium tuberculosis
inferred← citeshttps://doi.org/10.1089/dna.2007.0645openalex-snapshot
Efficient Systemic Expression of Bioactive IL-15 in Mice upon Delivery of Optimized DNA Expression Plasmids
inferred← citeshttps://doi.org/10.1089/hgtb.2013.022openalex-snapshot
Potential Limitations of the NSG Humanized Mouse as a Model System to Optimize Engineered Human T cell Therapy for Cancer
inferred← citeshttps://doi.org/10.1089/hgtb.2014.004openalex-snapshot
Manufacture of Gene-Modified Human T-Cells with a Memory Stem/Central Memory Phenotype
inferred← citeshttps://doi.org/10.1089/jir.2017.0101openalex-snapshot
IL-2 and Beyond in Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1089/rej.2011.1258openalex-snapshot
Pulmonary Delivery of Interleukin-7 Provides Efficient and Safe Delivery to the Aging Immune System
inferred← citeshttps://doi.org/10.1093/infdis/jir515openalex-snapshot
BCG Vaccination Induces Different Cytokine Profiles Following Infant BCG Vaccination in the UK and Malawi
inferred← citeshttps://doi.org/10.1097/01.cji.0000165356.03924.e7openalex-snapshot
Cytokine Signals in T-Cell Homeostasis
inferred← citeshttps://doi.org/10.1097/cji.0b013e31818403bcopenalex-snapshot
Dendritic Cells: A Critical Player in Cancer Therapy?
inferred← citeshttps://doi.org/10.1097/ppo.0b013e3181eacbc4openalex-snapshot
Novel Gamma-Chain Cytokines as Candidate Immune Modulators in Immune Therapies for Cancer
inferred← citeshttps://doi.org/10.1111/ajt.12719openalex-snapshot
IL-15 Induces Alloreactive CD28− Memory CD8 T Cell Proliferation and CTLA4-Ig Resistant Memory CD8 T Cell Activation
inferred← citeshttps://doi.org/10.1111/imm.12039openalex-snapshot
Human cord blood γδ T cells expressing public Vγ2 chains dominate the response to bisphosphonate plus interleukin‐15
inferred← citeshttps://doi.org/10.1111/imm.12092openalex-snapshot
Defective thymic progenitor development and mature T ‐cell responses in a mouse model for D own syndrome
inferred← citeshttps://doi.org/10.1111/imm.12500openalex-snapshot
Mathematical model reveals how regulating the three phases of T‐cell response could counteract immune evasion
inferred← citeshttps://doi.org/10.1111/imr.12538openalex-snapshot
Dying to protect: cell death and the control of T‐cell homeostasis
inferred← citeshttps://doi.org/10.1111/imr.12644openalex-snapshot
The role of cytokines in T‐cell memory in health and disease
inferred← citeshttps://doi.org/10.1111/imr.13306openalex-snapshot
Primary and secondary defects of the thymus
inferred← citeshttps://doi.org/10.1111/j.0105-2896.2006.00387.xopenalex-snapshot
Control of CD4+ T‐cell memory by cytokines and costimulators
inferred← citeshttps://doi.org/10.1111/j.0105-2896.2006.00391.xopenalex-snapshot
CD8 + T‐cell memory in tumor immunology and immunotherapy
inferred← citeshttps://doi.org/10.1111/j.1365-2567.2010.03316.xopenalex-snapshot
Evidence that CD8 T‐cell homeostasis and function remain intact during murine pregnancy
inferred← citeshttps://doi.org/10.1111/j.1365-2796.2009.02085.xopenalex-snapshot
Modulating T‐cell homeostasis with IL‐7: preclinical and clinical studies
inferred← citeshttps://doi.org/10.1111/j.1365-3083.2006.01847.xopenalex-snapshot
Long‐term Haematopoietic Reconstitution and Survival without Interleukin‐7 in a Murine Syngeneic Bone Marrow Transplantation Model
inferred← citeshttps://doi.org/10.1111/j.1600-065x.2007.00575.xopenalex-snapshot
Taming cancer by inducing immunity via dendritic cells
inferred← citeshttps://doi.org/10.1111/j.1600-065x.2008.00604.xopenalex-snapshot
Twelve immunotherapy drugs that could cure cancers
inferred← citeshttps://doi.org/10.1111/j.1600-065x.2008.00697.xopenalex-snapshot
Interleukin‐2 in the development and control of inflammatory disease
inferred← citeshttps://doi.org/10.1111/j.1600-0684.2007.00240.xopenalex-snapshot
Rapid modifications of peripheral T‐cell subsets that express CD127 in macaques treated with recombinant IL‐7
inferred← citeshttps://doi.org/10.1111/j.1749-6632.2009.05075.xopenalex-snapshot
Perspective on Potential Clinical Applications of Recombinant Human Interleukin‐7
inferred← citeshttps://doi.org/10.1126/scitranslmed.abg6986openalex-snapshot
A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia
inferred← citeshttps://doi.org/10.1128/jvi.00476-07openalex-snapshot
Interleukin-7 Enhances Proliferation Responses to T-Cell Receptor Stimulation in Naive CD4 + T Cells from Human Immunodeficiency Virus-Infected Persons
inferred← citeshttps://doi.org/10.1128/jvi.00534-14openalex-snapshot
Crucial Roles of Interleukin-7 in the Development of T Follicular Helper Cells and in the Induction of Humoral Immunity
inferred← citeshttps://doi.org/10.1128/jvi.02324-16openalex-snapshot
Overexpression of Interleukin-7 Extends the Humoral Immune Response Induced by Rabies Vaccination
inferred← citeshttps://doi.org/10.1128/jvi.05996-11openalex-snapshot
CD8 + T Cell Immunodominance in Lymphocytic Choriomeningitis Virus Infection Is Modified in the Presence of Toll-Like Receptor Agonists
inferred← citeshttps://doi.org/10.1148/radiol.2511072175openalex-snapshot
Radiofrequency Ablation Induces Antigen-presenting Cell Infiltration and Amplification of Weak Tumor-induced Immunity
inferred← citeshttps://doi.org/10.1155/2010/380697openalex-snapshot
Vaccines against Human Carcinomas: Strategies to Improve Antitumor Immune Responses
inferred← citeshttps://doi.org/10.1155/2020/4795171openalex-snapshot
Engineered IL‐7 Receptor Enhances the Therapeutic Effect of AXL‐CAR‐T Cells on Triple‐Negative Breast Cancer
inferred← citeshttps://doi.org/10.1158/0008-5472.can-07-2251openalex-snapshot
Chimeric NKG2D–Modified T Cells Inhibit Systemic T-Cell Lymphoma Growth in a Manner Involving Multiple Cytokines and Cytotoxic Pathways
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-11-0503openalex-snapshot
Determinants of Successful CD8+ T-Cell Adoptive Immunotherapy for Large Established Tumors in Mice
inferred← citeshttps://doi.org/10.1158/2159-8290.cd-17-0538openalex-snapshot
Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells
inferred← citeshttps://doi.org/10.1158/2767-9764.crc-24-0286openalex-snapshot
Activation of Cell-Intrinsic Signaling in CAR-T Cells via a Chimeric IL7R Domain
inferred← citeshttps://doi.org/10.1172/jci32020openalex-snapshot
Effects of IL-7 on memory CD8+ T cell homeostasis are influenced by the timing of therapy in mice
inferred← citeshttps://doi.org/10.1182/blood-2005-09-3560openalex-snapshot
Altered IL-7Rα expression with aging and the potential implications of IL-7 therapy on CD8+ T-cell immune responses
inferred← citeshttps://doi.org/10.1182/blood-2006-01-0177openalex-snapshot
Regulatory T-cell compartmentalization and trafficking
inferred← citeshttps://doi.org/10.1182/blood-2006-04-016857openalex-snapshot
Do CD8 effector cells need IL-7R expression to become resting memory cells?
inferred← citeshttps://doi.org/10.1182/blood-2006-11-057935openalex-snapshot
Vaccination regimens incorporating CpG-containing oligodeoxynucleotides and IL-2 generate antigen-specific antitumor immunity from T-cell populations undergoing homeostatic peripheral expansion after BMT
inferred← citeshttps://doi.org/10.1182/blood-2008-05-155309openalex-snapshot
IL-7 adjuvant treatment enhances long-term tumor antigen-specific CD8+ T-cell responses after immunization with recombinant lentivector
inferred← citeshttps://doi.org/10.1182/blood-2008-06-160945openalex-snapshot
IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response
inferred← citeshttps://doi.org/10.1182/blood-2008-08-173658openalex-snapshot
Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants
inferred← citeshttps://doi.org/10.1182/blood-2008-11-187385openalex-snapshot
Bone marrow deficient in IFN-γ signaling selectively reverses GVHD-associated immunosuppression and enhances a tumor-specific GVT effect
inferred← citeshttps://doi.org/10.1182/blood-2008-12-189266openalex-snapshot
Safety and immunologic effects of IL-15 administration in nonhuman primates
inferred← citeshttps://doi.org/10.1182/blood-2010-12-323154openalex-snapshot
Immunotherapeutic effects of IL-7 during a chronic viral infection in mice
inferred← citeshttps://doi.org/10.1182/blood-2015-05-645077openalex-snapshot
Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia
inferred← citeshttps://doi.org/10.1182/bloodadvances.2021006591openalex-snapshot
A single administration of hIL-7-hyFc induces long-lasting T-cell expansion with maintained effector functions
inferred← citeshttps://doi.org/10.1182/bloodadvances.2025018073openalex-snapshot
Zamtocabtagene autoleucel in relapsed/refractory B-NHL: 5-year follow-up of a CD20/19 tandem CAR T-cell phase 1 trial
inferred← citeshttps://doi.org/10.1186/1479-5876-4-36openalex-snapshot
Improved overall survival in dendritic cell vaccination-induced immunoreactive subgroup of advanced melanoma patients
inferred← citeshttps://doi.org/10.1186/1479-5876-9-162openalex-snapshot
Elevated levels of circulating IL-7 and IL-15 in patients with early stage prostate cancer
inferred← citeshttps://doi.org/10.1186/s12929-025-01154-6openalex-snapshot
Unraveling Cathepsin S regulation in interleukin-7-mediated anti-tumor immunity reveals its targeting potential against oral cancer
inferred← citeshttps://doi.org/10.1186/s40425-019-0549-5openalex-snapshot
Lymphopenia in Cancer Patients and its Effects on Response to Immunotherapy: an opportunity for combination with Cytokines?
inferred← citeshttps://doi.org/10.1189/jlb.0209086openalex-snapshot
IL-21 preferentially enhances IL-15-mediated homeostatic proliferation of human CD28+ CD8 memory T cells throughout the adult age span
inferred← citeshttps://doi.org/10.1189/jlb.0306147openalex-snapshot
Immunostimulatory combinations: designing the next generation of vaccine adjuvants
inferred← citeshttps://doi.org/10.1189/jlb.0313122openalex-snapshot
Jak/STAT and PI3K signaling pathways have both common and distinct roles in IL-7-mediated activities in human CD8+ T cells
inferred← citeshttps://doi.org/10.12688/f1000research.12999.1openalex-snapshot
IL-15 enhances cross-reactive antibody recall responses to seasonal H3 influenza viruses in vitro
inferred← citeshttps://doi.org/10.13016/m2330mopenalex-snapshot
The role of interleukin-12 for mTOR regulation of memory CTLs
inferred← citeshttps://doi.org/10.1371/journal.pone.0007965openalex-snapshot
Cancer Associated Fibroblasts Promote Tumor Growth and Metastasis by Modulating the Tumor Immune Microenvironment in a 4T1 Murine Breast Cancer Model
inferred← citeshttps://doi.org/10.1371/journal.pone.0016097openalex-snapshot
Co-Administration of IL-1+IL-6+TNF-α with Mycobacterium tuberculosis Infected Macrophages Vaccine Induces Better Protective T Cell Memory than BCG
inferred← citeshttps://doi.org/10.1371/journal.pone.0037801openalex-snapshot
IL-12 and GM-CSF in DNA/MVA Immunizations against HIV-1 CRF12_BF Nef Induced T-Cell Responses With an Enhanced Magnitude, Breadth and Quality
inferred← citeshttps://doi.org/10.1371/journal.pone.0058860openalex-snapshot
Val-BoroPro Accelerates T Cell Priming via Modulation of Dendritic Cell Trafficking Resulting in Complete Regression of Established Murine Tumors
inferred← citeshttps://doi.org/10.1371/journal.pone.0159690openalex-snapshot
Interleukin-7 Modulates Anti-Tumor CD8+ T Cell Responses via Its Action on Host Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0176495openalex-snapshot
Diminished plasma levels of common γ-chain cytokines in pulmonary tuberculosis and reversal following treatment
inferred← citeshttps://doi.org/10.1517/14712590903260785openalex-snapshot
Treatment of lymphoma with adoptively transferred T cells
inferred← citeshttps://doi.org/10.1517/14712590903431022openalex-snapshot
Immune-based therapeutics for pediatric cancer
inferred← citeshttps://doi.org/10.1517/14712598.2012.668516openalex-snapshot
Poxviral vectors for cancer immunotherapy
inferred← citeshttps://doi.org/10.1517/14712598.7.10.1563openalex-snapshot
The potential of topical DNA vaccines adjuvanted by cytokines
inferred← citeshttps://doi.org/10.1586/14760584.2014.905746openalex-snapshot
The BCG replacement vaccine VPM1002: from drawing board to clinical trial
inferred← citeshttps://doi.org/10.1586/1744666x.1.3.443openalex-snapshot
Immunosenescence: immune deficits in the elderly and therapeutic strategies to enhance immune competence
inferred← citeshttps://doi.org/10.1586/eci.10.102openalex-snapshot
Stimulating natural killer cells to protect against cancer: recent developments
inferred← citeshttps://doi.org/10.17169/refubium-7489openalex-snapshot
Appraisal of second-generation BCG ΔureC::hly experimental vaccine candidates co-expressing human interleukin 7 or interleukin 18.
inferred← citeshttps://doi.org/10.17863/cam.80296openalex-snapshot
Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation.
inferred← citeshttps://doi.org/10.18632/oncotarget.7044openalex-snapshot
Human melanoma immunotherapy using tumor antigen-specific T cells generated in humanized mice
inferred← citeshttps://doi.org/10.2174/0113862073293963240409040110openalex-snapshot
IL-7R Expression Correlates with Prognosis in Breast Cancer
inferred← citeshttps://doi.org/10.2174/157018006778194655openalex-snapshot
Utilizing IL-12, IL-15 and IL-7 as Mucosal Vaccine Adjuvants
inferred← citeshttps://doi.org/10.25772/c6a3-f034openalex-snapshot
AUGMENTATION OF T CELL EXPANSION FOR ADOPTIVE IMMUNOTHERAPY BY ALTERNATE GAMMA CHAIN CYTOKINES AND BY GEMCITABINE MEDIATED INHIBITION OF MYELOID DERIVED SUPPRESSOR CELLS
inferred← citeshttps://doi.org/10.31274/rtd-180813-16639openalex-snapshot
Interleukin-15 and [alpha](1,3)galactosyl-expressing vaccine combination therapy for melanoma
inferred← citeshttps://doi.org/10.3324/haematol.2023.282875openalex-snapshot
CAR T-cell therapy for central nervous system lymphomas: blood and cerebrospinal fluid biology, and outcomes
inferred← citeshttps://doi.org/10.3389/fbioe.2021.795300openalex-snapshot
Electrical Stimulation for Immune Modulation in Cancer Treatments
inferred← citeshttps://doi.org/10.3389/fimmu.2013.00020openalex-snapshot
Role of PI3K/Akt signaling in memory CD8 T cell differentiation
inferred← citeshttps://doi.org/10.3389/fimmu.2021.680442openalex-snapshot
The Broad Immunomodulatory Effects of IL-7 and Its Application In Vaccines
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