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Abrogation of TGF-β signaling enhances chemokine production and correlates with prognosis in human breast cancer

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.285.22.2859openalex-snapshot

Association Between the T29→C Polymorphism in the Transforming Growth Factor β1 Gene and Breast Cancer Among Elderly White Women

inferredcites →https://doi.org/10.1002/gene.10046openalex-snapshot

Conditional inactivation of the TGF‐β type II receptor using Cre:Lox

inferredcites →https://doi.org/10.1007/s10585-004-5458-3openalex-snapshot

Constitutive expression of growth regulated oncogene (gro) in human colon carcinoma cells with different metastatic potential and its role in regulating their metastatic phenotype

inferredcites →https://doi.org/10.1016/0303-7207(96)03761-6openalex-snapshot

Expression of transcripts of interleukin-6 and related cytokines by human breast tumors, breast cancer cells, and adipose stromal cells

inferredcites →https://doi.org/10.1016/j.ccr.2007.01.013openalex-snapshot

Molecular Definition of Breast Tumor Heterogeneity

inferredcites →https://doi.org/10.1016/j.ccr.2007.12.004openalex-snapshot

Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis

inferredcites →https://doi.org/10.1016/j.cell.2004.06.006openalex-snapshot

Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

inferredcites →https://doi.org/10.1016/j.cell.2008.01.046openalex-snapshot

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

inferredcites →https://doi.org/10.1016/j.cyto.2006.03.004openalex-snapshot

Oncostatin M induces cell detachment and enhances the metastatic capacity of T-47D human breast carcinoma cells

inferredcites →https://doi.org/10.1016/s0002-9440(10)63510-9openalex-snapshot

Transgenic Mice Expressing a Dominant-Negative Mutant Type II Transforming Growth Factor-β Receptor Exhibit Impaired Mammary Development and Enhanced Mammary Tumor Formation

inferredcites →https://doi.org/10.1016/s0021-9258(18)47215-8openalex-snapshot

Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells

inferredcites →https://doi.org/10.1016/s0039-6109(05)70447-3openalex-snapshot

INFLAMMATORY BREAST CANCER

inferredcites →https://doi.org/10.1016/s0960-9822(07)00533-7openalex-snapshot

TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis

inferredcites →https://doi.org/10.1023/b:clin.0000024760.02667.dbopenalex-snapshot

Oncostatin M stimulates the detachment of a reservoir of invasive mammary carcinoma cells: Role of cyclooxygenase-2

inferredcites →https://doi.org/10.1038/35021093openalex-snapshot

Molecular portraits of human breast tumours

inferredcites →https://doi.org/10.1038/35065016openalex-snapshot

Involvement of chemokine receptors in breast cancer metastasis

inferredcites →https://doi.org/10.1038/415530aopenalex-snapshot

Gene expression profiling predicts clinical outcome of breast cancer

inferredcites →https://doi.org/10.1038/nature03799openalex-snapshot

Genes that mediate breast cancer metastasis to lung

inferredcites →https://doi.org/10.1038/ncb807openalex-snapshot

Metastasis is driven by sequential elevation of H-ras and Smad2 levels

inferredcites →https://doi.org/10.1038/ng1901openalex-snapshot

Genome-wide analysis of estrogen receptor binding sites

inferredcites →https://doi.org/10.1038/sj.onc.1204312openalex-snapshot

Reducing mammary cancer risk through premature stem cell senescence

inferredcites →https://doi.org/10.1038/sj.onc.1208964openalex-snapshot

Activated type I TGFβ receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression

inferredcites →https://doi.org/10.1046/j.1365-2559.2000.00841.xopenalex-snapshot

Loss of expression of transforming growth factor beta type II receptor correlates with high tumour grade in human breast in‐situ and invasive carcinomas

inferredcites →https://doi.org/10.1056/nejmoa021967openalex-snapshot

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

inferredcites →https://doi.org/10.1073/pnas.0932636100openalex-snapshot

Transforming growth factor β signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

inferredcites →https://doi.org/10.1073/pnas.0932692100openalex-snapshot

Repeated observation of breast tumor subtypes in independent gene expression data sets

inferredcites →https://doi.org/10.1073/pnas.191367098openalex-snapshot

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

inferredcites →https://doi.org/10.1073/pnas.92.10.4254openalex-snapshot

Mammary tumor suppression by transforming growth factor beta 1 transgene expression.

inferredcites →https://doi.org/10.1093/biostatistics/4.2.249openalex-snapshot

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

inferredcites →https://doi.org/10.1093/jnci/91.24.2096openalex-snapshot

Transforming Growth Factor-β and Breast Cancer Risk in Women With Mammary Epithelial Hyperplasia

inferredcites →https://doi.org/10.1128/mcb.00787-08openalex-snapshot

Transforming Growth Factor β Engages TACE and ErbB3 To Activate Phosphatidylinositol-3 Kinase/Akt in ErbB2-Overexpressing Breast Cancer and Desensitizes Cells to Trastuzumab

inferredcites →https://doi.org/10.1128/mcb.23.23.8691-8703.2003openalex-snapshot

Increased Malignancy of Neu-Induced Mammary Tumors Overexpressing Active Transforming Growth Factor β1

inferredcites →https://doi.org/10.1152/ajpcell.00322.2005openalex-snapshot

Oncostatin M differentially regulates CXC chemokines in mouse cardiac fibroblasts

inferredcites →https://doi.org/10.1158/0008-5472.can-04-2111openalex-snapshot

Conditional Overexpression of Active Transforming Growth Factor β1 In vivo Accelerates Metastases of Transgenic Mammary Tumors

inferredcites →https://doi.org/10.1158/0008-5472.can-04-3272openalex-snapshot

Effect of Conditional Knockout of the Type II TGF-β Receptor Gene in Mammary Epithelia on Mammary Gland Development and Polyomavirus Middle T Antigen Induced Tumor Formation and Metastasis

inferredcites →https://doi.org/10.1158/0008-5472.can-05-4414openalex-snapshot

Genetic Reclassification of Histologic Grade Delineates New Clinical Subtypes of Breast Cancer

inferredcites →https://doi.org/10.1158/0008-5472.can-07-2938openalex-snapshot

Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways

inferredcites →https://doi.org/10.1158/0008-5472.can-07-5597openalex-snapshot

Transforming Growth Factor–β Regulates Mammary Carcinoma Cell Survival and Interaction with the Adjacent Microenvironment

inferredcites →https://doi.org/10.1158/1078-0432.ccr-07-1922openalex-snapshot

Secreted CXCL1 Is a Potential Mediator and Marker of the Tumor Invasion of Bladder Cancer

inferredcites →https://doi.org/10.1172/jci15333openalex-snapshot

Lifetime exposure to a soluble TGF-β antagonist protects mice against metastasis without adverse side effects

inferredcites →https://doi.org/10.1172/jci200522320openalex-snapshot

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

inferredcites →https://doi.org/10.1186/1471-2164-9-239openalex-snapshot

Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen

inferredcites →https://doi.org/10.1186/bcr778openalex-snapshot

Induction by transforming growth factor-β1 of epithelial to mesenchymal transition is a rare event in vitro

inferredcites →https://doi.org/10.1200/jco.2006.07.1522openalex-snapshot

Definition of Clinically Distinct Molecular Subtypes in Estrogen Receptor–Positive Breast Carcinomas Through Genomic Grade

inferredcites →https://doi.org/10.1200/jco.2008.18.1370openalex-snapshot

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

inferredcites →https://doi.org/10.1529/biophysj.107.113613openalex-snapshot

Breakdown of the Endothelial Barrier Function in Tumor Cell Transmigration

inferredcites →https://doi.org/10.1593/neo.07815openalex-snapshot

Endothelial Cells Enhance Tumor Cell Invasion through a Crosstalk Mediated by CXC Chemokine Signaling

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Associations between genetic variants in the TGF-β signaling pathway and breast cancer risk among Hispanic and non-Hispanic white women

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TGFβ1 pathway components in breast cancer tissue from aggressive subtypes correlate with better prognostic parameters in ER-positive and p53-negative cancers

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Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties

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Inflammation-Mediated Genetic and Epigenetic Alterations Drive Cancer Development in the Neighboring Epithelium upon Stromal Abrogation of TGF-β Signaling

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Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-κB target genes in human breast cancer

inferred← citeshttps://doi.org/10.18632/oncotarget.9885openalex-snapshot

Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment

inferred← citeshttps://doi.org/10.2106/jbjs.17.01230openalex-snapshot

Periostin Promotes Fibroblast Migration and Inhibits Muscle Repair After Skeletal Muscle Injury

inferred← citeshttps://doi.org/10.2147/cmar.s278382openalex-snapshot

Nomogram Including Elastography for Prediction of Contralateral Central Lymph Node Metastasis in Solitary Papillary Thyroid Carcinoma Preoperatively

inferred← citeshttps://doi.org/10.2174/138920111798808284openalex-snapshot

The Complexities of TGF-β Action During Mammary and Squamous Cell Carcinogenesis

inferred← citeshttps://doi.org/10.2217/bmt.13.74openalex-snapshot

Chemotherapeutic targeting of the TGF-β pathway in breast cancers

inferred← citeshttps://doi.org/10.2217/fon.09.138openalex-snapshot

Emerging Therapeutic Targets in Breast Cancer Bone Metastasis

inferred← citeshttps://doi.org/10.23736/s0393-3660.19.04058-0openalex-snapshot

Advances in research on the role of interleukin-11 in cardiovascular system

inferred← citeshttps://doi.org/10.2967/jnumed.111.092809openalex-snapshot

PET with the89Zr-Labeled Transforming Growth Factor-β Antibody Fresolimumab in Tumor Models

inferred← citeshttps://doi.org/10.2967/jnumed.115.167932openalex-snapshot

Targeted Imaging of the Atypical Chemokine Receptor 3 (ACKR3/CXCR7) in Human Cancer Xenografts

inferred← citeshttps://doi.org/10.3109/1547691x.2014.945667openalex-snapshot

TGF β : A player on multiple fronts in the tumor microenvironment

inferred← citeshttps://doi.org/10.3389/fbioe.2022.988683openalex-snapshot

Multifunctional biomaterial platforms for blocking the fibrosis process and promoting cellular restoring effects in myocardial fibrosis therapy

inferred← citeshttps://doi.org/10.3389/fphar.2021.646331openalex-snapshot

Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling

inferred← citeshttps://doi.org/10.3390/cancers13112584openalex-snapshot

Pivotal Role for Cxcr2 in Regulating Tumor-Associated Neutrophil in Breast Cancer

inferred← citeshttps://doi.org/10.3390/genes12070975openalex-snapshot

Skeletal Deformities in Osterix-Cre;Tgfbr2f/f Mice May Cause Postnatal Death

inferred← citeshttps://doi.org/10.3390/gidisord1020024openalex-snapshot

Immunomodulatory Effects of TGF-β Family Signaling within Intestinal Epithelial Cells and Carcinomas

inferred← citeshttps://doi.org/10.3390/ijms24087262openalex-snapshot

Involvement in Tumorigenesis and Clinical Significance of CXCL1 in Reproductive Cancers: Breast Cancer, Cervical Cancer, Endometrial Cancer, Ovarian Cancer and Prostate Cancer

inferred← citeshttps://doi.org/10.3892/mmr.2014.2891openalex-snapshot

Dihydromyricetin induces mouse hepatoma Hepal-6 cell apoptosis via the transforming growth factor-β pathway

inferred← citeshttps://doi.org/10.4172/1948-5956.1000098openalex-snapshot

Differential Gene Expression Pattern of Transforming Growth Factor Beta-1 in Early and Advanced Breast Cancers

inferred← citeshttps://doi.org/10.4172/2155-9929.1000153openalex-snapshot

A Canonical Transforming Growth Factor Beta-Dependent Signaling Pathway is Present in Peripheral Blood Cells of Cancer Patients with Skeletal Metastasis

inferred← citeshttps://doi.org/10.4236/jct.2014.57082openalex-snapshot

Targeting Transforming Growth Factor-β (TGF-β) in Cancer and Non-Neoplastic Diseases

inferred← citeshttps://doi.org/10.5167/uzh-102646openalex-snapshot

A New Approach to Cancer Therapy: The Tumor Microenvironment as Target

inferred← citeshttps://doi.org/10.58830/ozgur.pub80.c355openalex-snapshot

Meme Kanseri Tedavisinde Sinyal Yolaklarının Kritik Rolü

inferred← citeshttps://doi.org/10.7150/ijbs.4564openalex-snapshot

Complexities of TGF-β Targeted Cancer Therapy

inferred← citeshttps://doi.org/10.7150/jca.48418openalex-snapshot

MiR-146b-3p regulates proliferation of pancreatic cancer cells with stem cell-like properties by targeting MAP3K10

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.