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Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

https://doi.org/10.1172/jci45862
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Association of Increased Immunostaining for Inducible Nitric Oxide Synthase and Nitrotyrosine With Fibroblast Growth Factor Transformation in Pancreatic Cancer
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Nitric oxide synthase expression and nitric oxide production in human colon carcinoma tissue
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Increased protein nitrosylation in head and neck squamous cell carcinogenesis
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Hydrogen peroxide secreted by tumor‐derived macrophages down‐modulates signal‐transducing zeta molecules and inhibits tumor‐specific T cell‐and natural killer cell‐mediated cytotoxicity
inferredcites →https://doi.org/10.1002/ijc.21767openalex-snapshot
Tumor iNOS predicts poor survival for stage III melanoma patients
inferredcites →https://doi.org/10.1002/ijc.23437openalex-snapshot
Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression
inferredcites →https://doi.org/10.1002/jemt.10098openalex-snapshot
Oxidative stress in phagocytes—“The enemy within”
inferredcites →https://doi.org/10.1007/978-0-387-69118-3openalex-snapshot
Tumor-induced immune suppression : mechanisms and therapeutic reversal
inferredcites →https://doi.org/10.1007/s00726-003-0018-8openalex-snapshot
Peroxynitrite reactivity with amino acids and proteins
inferredcites →https://doi.org/10.1016/j.coi.2009.02.004openalex-snapshot
Adoptive immunotherapy of cancer using CD4+ T cells
inferredcites →https://doi.org/10.1016/j.coi.2009.03.002openalex-snapshot
Adoptive cell therapy for the treatment of patients with metastatic melanoma
inferredcites →https://doi.org/10.1016/j.coi.2010.04.005openalex-snapshot
Targeting inhibitory pathways in cancer immunotherapy
inferredcites →https://doi.org/10.1016/j.semcancer.2005.04.004openalex-snapshot
Inducible nitric oxide synthase (iNOS) in tumor biology: The two sides of the same coin
inferredcites →https://doi.org/10.1016/s0960-894x(98)00479-xopenalex-snapshot
Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages
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Localization, Quantitation, and In Situ Detection of Specific Peptide–MHC Class I Complexes Using a Monoclonal Antibody
inferredcites →https://doi.org/10.1038/nature01322openalex-snapshot
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inferredcites →https://doi.org/10.1038/ni1001-907openalex-snapshot
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inferredcites →https://doi.org/10.1038/nrc2129openalex-snapshot
Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer
inferredcites →https://doi.org/10.1038/nri2506openalex-snapshot
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inferredcites →https://doi.org/10.1046/j.1365-2133.2000.03352.xopenalex-snapshot
Expression of the inducible isoform of nitric oxide synthase in pigment cell lesions of the skin
inferredcites →https://doi.org/10.1073/pnas.0500815102openalex-snapshot
Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress
inferredcites →https://doi.org/10.1073/pnas.93.23.13119openalex-snapshot
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inferredcites →https://doi.org/10.1084/jem.181.5.1881openalex-snapshot
Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex.
inferredcites →https://doi.org/10.1084/jem.20030590openalex-snapshot
Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells
inferredcites →https://doi.org/10.1084/jem.20042028openalex-snapshot
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inferredcites →https://doi.org/10.1084/jem.20100587openalex-snapshot
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inferredcites →https://doi.org/10.1097/cji.0b013e3181b88ffcopenalex-snapshot
Increased Intensity Lymphodepletion Enhances Tumor Treatment Efficacy of Adoptively Transferred Tumor-specific T Cells
inferredcites →https://doi.org/10.1097/ppo.0b013e3181a7450fopenalex-snapshot
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inferredcites →https://doi.org/10.1111/j.1600-065x.2008.00615.xopenalex-snapshot
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inferredcites →https://doi.org/10.1111/j.1755-148x.2009.00634.xopenalex-snapshot
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inferredcites →https://doi.org/10.1126/science.1177627openalex-snapshot
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inferredcites →https://doi.org/10.1158/0008-5472.can-10-1439openalex-snapshot
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inferredcites →https://doi.org/10.1158/1078-0432.ccr-05-1269openalex-snapshot
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inferredcites →https://doi.org/10.1158/1078-0432.ccr-07-1378openalex-snapshot
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inferredcites →https://doi.org/10.1158/1078-0432.ccr-09-3272openalex-snapshot
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inferredcites →https://doi.org/10.1164/rccm.200411-1523ocopenalex-snapshot
Abnormalities in Nitric Oxide and Its Derivatives in Lung Cancer
inferredcites →https://doi.org/10.1165/rcmb.2003-0409ocopenalex-snapshot
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inferredcites →https://doi.org/10.1172/jci0215175openalex-snapshot
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inferredcites →https://doi.org/10.1172/jci15175openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.0900092openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.171.2.528openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.172.2.989openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.175.7.4583openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.176.1.284openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.180.9.5956openalex-snapshot
Conversion of Tyrosine to the Inflammation-Associated Analog 3′-Nitrotyrosine at Either TCR- or MHC-Contact Positions Can Profoundly Affect Recognition of the MHC Class I-Restricted Epitope of Lymphocytic Choriomeningitis Virus Glycoprotein 33 by CD8 T Cells

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Tumor-Promoting/Associated Inflammation and the Microenvironment: A State of the Science and New Horizons
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A transplantable TH‐MYCN transgenic tumor model in C57Bl/6 mice for preclinical immunological studies in neuroblastoma
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Subpopulations of myeloid‐derived suppressor cells impair T cell responses through independent nitric oxide‐related pathways
inferred← citeshttps://doi.org/10.1002/jcp.30643openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-3-319-67577-0_8openalex-snapshot
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Molecular mechanisms orchestrating the origin, expansion, and function of myeloid-derived suppressor cells
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Breast Cancer Immunology and Immunotherapy
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Madecassic acid alleviates colitis-associated colorectal cancer by blocking the recruitment of myeloid-derived suppressor cells via the inhibition of IL-17 expression in γδT17 cells
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Fluorescence imaging guided CpG nanoparticles-loaded IR820-hydrogel for synergistic photothermal immunotherapy
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27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression
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KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer
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Oxidative Stress in Cancer
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Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy
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Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
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CXCR2-Expressing Myeloid-Derived Suppressor Cells Are Essential to Promote Colitis-Associated Tumorigenesis
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Inhibition of hexokinase 2 with 3-BrPA promotes MDSCs differentiation and immunosuppressive function
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Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer
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Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells
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On the armament and appearances of human myeloid-derived suppressor cells
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A2A adenosine receptor antagonists to weaken the hypoxia-HIF-1α driven immunosuppression and improve immunotherapies of cancer
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Immune watchdogs: Tissue-resident lymphocytes as key players in cancer defense
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Inhibition of Hedgehog signaling in the gastrointestinal tract: Targeting the cancer microenvironment
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A review of the efficacy of prostate cancer therapies against castration-resistant prostate cancer
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Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 4
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Thyroid dysfunction (TD) induced by PD-1/PD-L1 inhibitors in advanced lung cancer
inferred← citeshttps://doi.org/10.1016/j.humimm.2016.12.001openalex-snapshot
Suppression of T cells by myeloid-derived suppressor cells in cancer
inferred← citeshttps://doi.org/10.1016/j.imbio.2013.07.003openalex-snapshot
Modulation of CD8+ T-cell activation events by monocytic and granulocytic myeloid-derived suppressor cells
inferred← citeshttps://doi.org/10.1016/j.imbio.2014.07.017openalex-snapshot
Myeloid regulatory cells in tumor spreading and metastasis
inferred← citeshttps://doi.org/10.1016/j.immuni.2014.08.015openalex-snapshot
The Stress-Response Sensor Chop Regulates the Function and Accumulation of Myeloid-Derived Suppressor Cells in Tumors
inferred← citeshttps://doi.org/10.1016/j.immuni.2025.04.027openalex-snapshot
Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells
inferred← citeshttps://doi.org/10.1016/j.intimp.2018.10.026openalex-snapshot
Immune regulation and anti-cancer activity by lipid inflammatory mediators
inferred← citeshttps://doi.org/10.1016/j.intimp.2021.107627openalex-snapshot
Role of immune regulatory cells in breast cancer: Foe or friend?
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110581openalex-snapshot
Mononuclear myeloid-derived suppressor cells expansion is associated with progression of liver failure in patients with acute decompensation of cirrhosis
inferred← citeshttps://doi.org/10.1016/j.isci.2024.109546openalex-snapshot
Disruption of CD47-SIRPα signaling restores inflammatory function in tumor-associated myeloid-derived suppressor cells
inferred← citeshttps://doi.org/10.1016/j.it.2011.12.001openalex-snapshot
Differential macrophage programming in the tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.it.2015.02.004openalex-snapshot
Macrophages and cancer: from mechanisms to therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.jaci.2014.04.035openalex-snapshot
Myeloid-derived suppressor cell function is diminished in aspirin-triggered allergic airway hyperresponsiveness in mice
inferred← citeshttps://doi.org/10.1016/j.jconrel.2017.03.395openalex-snapshot
Targeting tumor associated macrophages (TAMs) via nanocarriers
inferred← citeshttps://doi.org/10.1016/j.jddst.2024.106589openalex-snapshot
Transforming cancer immunotherapy: Overcoming immunosuppression in tumors via gene silencing techniques based on nanoparticles
inferred← citeshttps://doi.org/10.1016/j.jiec.2020.01.017openalex-snapshot
Enhancement of antitumor effect of radiotherapy via combination with Au@SiO2 nanoparticles targeted to tumor-associated macrophages
inferred← citeshttps://doi.org/10.1016/j.lpm.2016.06.017openalex-snapshot
Past, present and forecast of transfusion medicine: What has changed and what is expected to change?
inferred← citeshttps://doi.org/10.1016/j.maturitas.2013.06.010openalex-snapshot
Can exercise-related improvements in immunity influence cancer prevention and prognosis in the elderly?
inferred← citeshttps://doi.org/10.1016/j.mce.2013.06.003openalex-snapshot
The immune system and inflammation in breast cancer
inferred← citeshttps://doi.org/10.1016/j.mvr.2021.104189openalex-snapshot
The heterogeneity of cancer endothelium: The relevance of angiogenesis and endothelial progenitor cells in cancer microenvironment
inferred← citeshttps://doi.org/10.1016/j.nantod.2022.101641openalex-snapshot
Nanomodulators targeting tumor-resident immunosuppressive cells: Mechanisms and recent updates
inferred← citeshttps://doi.org/10.1016/j.pan.2017.11.003openalex-snapshot
Intratumoural leukocyte infiltration is a prognostic indicator among pancreatic cancer patients with type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.prp.2026.156658openalex-snapshot
Reprogramming tumor-associated macrophages and interferon-gamma signaling to overcome therapeutic resistance in cancer
inferred← citeshttps://doi.org/10.1016/j.redox.2021.101891openalex-snapshot
Immune cell - produced ROS and their impact on tumor growth and metastasis
inferred← citeshttps://doi.org/10.1016/j.semcancer.2012.01.010openalex-snapshot
Regulation of suppressive function of myeloid-derived suppressor cells by CD4+ T cells
inferred← citeshttps://doi.org/10.1016/j.semcancer.2012.01.011openalex-snapshot
Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression
inferred← citeshttps://doi.org/10.1016/j.semcancer.2013.02.007openalex-snapshot
The kinship of neutrophils and granulocytic myeloid-derived suppressor cells in cancer: Cousins, siblings or twins?
inferred← citeshttps://doi.org/10.1016/j.semradonc.2014.07.008openalex-snapshot
Myeloid-Derived Cells in Tumors: Effects of Radiation
inferred← citeshttps://doi.org/10.1016/j.xcrm.2022.100787openalex-snapshot
Peroxynitrite promotes immune evasion by reducing tumor antigenicity
inferred← citeshttps://doi.org/10.1021/acsptsci.3c00014openalex-snapshot
Fluorescent Detection of Peroxynitrite Produced by Myeloid-Derived Suppressor Cells in Cancer and Inhibition by Dasatinib
inferred← citeshttps://doi.org/10.1038/cdd.2016.131openalex-snapshot
Double-stranded RNA promotes CTL-independent tumor cytolysis mediated by CD11b+Ly6G+ intratumor myeloid cells through the TICAM-1 signaling pathway
inferred← citeshttps://doi.org/10.1038/ncomms12150openalex-snapshot
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
inferred← citeshttps://doi.org/10.1038/nrc.2016.54openalex-snapshot
The role of myeloid cells in cancer therapies
inferred← citeshttps://doi.org/10.1038/nri3175openalex-snapshot
Coordinated regulation of myeloid cells by tumours
inferred← citeshttps://doi.org/10.1038/onc.2013.257openalex-snapshot
The immune network in pancreatic cancer development and progression
inferred← citeshttps://doi.org/10.1038/onc.2016.288openalex-snapshot
Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma
inferred← citeshttps://doi.org/10.1038/s41388-020-1200-0openalex-snapshot
BMP9 signaling promotes the normalization of tumor blood vessels
inferred← citeshttps://doi.org/10.1038/s41388-024-03100-6openalex-snapshot
PIM1/NF-κB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC
inferred← citeshttps://doi.org/10.1038/s41391-024-00825-zopenalex-snapshot
Targeting the tumor microenvironment, a new therapeutic approach for prostate cancer
inferred← citeshttps://doi.org/10.1038/s41392-021-00670-9openalex-snapshot
Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer
inferred← citeshttps://doi.org/10.1038/s41417-025-00886-9openalex-snapshot
MDSC checkpoint blockade therapy: a new breakthrough point overcoming immunosuppression in cancer immunotherapy
inferred← citeshttps://doi.org/10.1038/s41419-017-0194-1openalex-snapshot
Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β production
inferred← citeshttps://doi.org/10.1038/s41467-022-29000-5openalex-snapshot
Targeting myeloid derived suppressor cells reverts immune suppression and sensitizes BRAF-mutant papillary thyroid cancer to MAPK inhibitors
inferred← citeshttps://doi.org/10.1038/s41467-023-41470-9openalex-snapshot
Metabolic Reprogramming via ACOD1 depletion enhances function of human induced pluripotent stem cell-derived CAR-macrophages in solid tumors
inferred← citeshttps://doi.org/10.1038/s41467-025-58319-yopenalex-snapshot
SCFA biotherapy delays diabetes in humanized gnotobiotic mice by remodeling mucosal homeostasis and metabolome
inferred← citeshttps://doi.org/10.1038/s41577-019-0127-6openalex-snapshot
Macrophages as regulators of tumour immunity and immunotherapy
inferred← citeshttps://doi.org/10.1038/s41577-020-00490-yopenalex-snapshot
Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity
inferred← citeshttps://doi.org/10.1038/s41590-022-01153-xopenalex-snapshot
Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity
inferred← citeshttps://doi.org/10.1038/s41590-024-02029-yopenalex-snapshot
The heterogeneity of neutrophils in cancer and its implication for therapeutic targeting
inferred← citeshttps://doi.org/10.1038/s42003-021-02376-8openalex-snapshot
Neutrophil-derived reactive oxygen species promote tumor colonization
inferred← citeshttps://doi.org/10.1038/srep13650openalex-snapshot
IL-11 induces differentiation of myeloid-derived suppressor cells through activation of STAT3 signalling pathway
inferred← citeshttps://doi.org/10.1049/syb2.12097openalex-snapshot
A tumour‐associated macrophage‐based signature for deciphering prognosis and immunotherapy response in prostate cancer
inferred← citeshttps://doi.org/10.1073/pnas.1905005116openalex-snapshot
Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade
inferred← citeshttps://doi.org/10.1080/07357907.2021.2016800openalex-snapshot
An Introduction to the Relationship Between Lewis x and Malignancy Mainly Related to Breast Cancer and Head Neck Squamous Cell Carcinoma (HNSCC)
inferred← citeshttps://doi.org/10.1080/08830185.2024.2401352openalex-snapshot
The molecular landscape of T cell exhaustion in the tumor microenvironment and reinvigoration strategies
inferred← citeshttps://doi.org/10.1080/09553002.2019.1547435openalex-snapshot
Effect of gamma irradiation doses in the structural and functional properties of mice splenic cells
inferred← citeshttps://doi.org/10.1080/09553002.2021.1956005openalex-snapshot
Reconciling two opposing effects of radiation therapy: stimulation of cancer cell invasion and activation of anti-cancer immunity
inferred← citeshttps://doi.org/10.1080/09553002.2024.2331115openalex-snapshot
Targeting two radiation-induced immunosuppressive pathways to improve the efficacy of normofractionated radiation therapy in a preclinical colorectal cancer model
inferred← citeshttps://doi.org/10.1080/1061186x.2018.1474360openalex-snapshot
Modulating T-cell-based cancer immunotherapy via particulate systems
inferred← citeshttps://doi.org/10.1080/2162402x.2014.995541openalex-snapshot
Characterization of the myeloid-derived suppressor cell subset regulated by NK cells in malignant lymphoma
inferred← citeshttps://doi.org/10.1080/2162402x.2015.1019195openalex-snapshot
The nitric oxide radical scavenger carboxy-PTIO reduces the immunosuppressive activity of myeloid-derived suppressor cells and potentiates the antitumor activity of adoptive cytotoxic T lymphocyte immunotherapy
inferred← citeshttps://doi.org/10.1080/2162402x.2015.1044712openalex-snapshot
COX-2 promotes metastasis in nasopharyngeal carcinoma by mediating interactions between cancer cells and myeloid-derived suppressor cells
inferred← citeshttps://doi.org/10.1080/2162402x.2016.1164919openalex-snapshot
Anti-GD2 mAb and Vorinostat synergize in the treatment of neuroblastoma
inferred← citeshttps://doi.org/10.1080/2162402x.2016.1252013openalex-snapshot
Immunosuppressive CD14 + HLA-DR lo/neg monocytes are elevated in pancreatic cancer and “primed” by tumor-derived exosomes
inferred← citeshttps://doi.org/10.1080/2162402x.2018.1509821openalex-snapshot
Whole cell melanoma vaccine genetically modified to stem cells like phenotype generates specific immune responses to ALDH1A1 and long-term survival in advanced melanoma patients
inferred← citeshttps://doi.org/10.1080/21655979.2021.1899532openalex-snapshot
Effect of CMNa combined with radiotherapy on the tumor immune microenvironment of mouse cervical cancer cell transplantation tumor model
inferred← citeshttps://doi.org/10.1080/21691401.2019.1687504openalex-snapshot
The role of myeloid-derived suppressor cells in the pathogenesis of rheumatoid arthritis; anti- or pro-inflammatory cells?
inferred← citeshttps://doi.org/10.1093/cei/uxac025openalex-snapshot
MDSCs and T cells in solid tumors and non-Hodgkin lymphomas: an immunosuppressive speech
inferred← citeshttps://doi.org/10.1093/ejcts/ezx492openalex-snapshot
Blood and lymphatic vessels contribute to the impact of the immune microenvironment on clinical outcome in non-small-cell lung cancer†
inferred← citeshttps://doi.org/10.1093/immadv/ltag001openalex-snapshot
Comprehensive spatial and immune profiling of metastatic mismatch repair–deficient colorectal cancer reveals response to immunotherapy
inferred← citeshttps://doi.org/10.1093/jnci/djs629openalex-snapshot
Combining Radiotherapy and Cancer Immunotherapy: A Paradigm Shift
inferred← citeshttps://doi.org/10.1097/cji.0000000000000497openalex-snapshot
A New Method for Constructing Macrophage-Associated Predictors of Treatment Efficacy Based on Single-Cell Sequencing Analysis
inferred← citeshttps://doi.org/10.1097/j.pain.0000000000000681openalex-snapshot
The cystine/glutamate antiporter system xc − drives breast tumor cell glutamate release and cancer-induced bone pain
inferred← citeshttps://doi.org/10.1097/md.0000000000005541openalex-snapshot
Role of immune cells in pancreatic cancer from bench to clinical application
inferred← citeshttps://doi.org/10.1097/ppo.0000000000000240openalex-snapshot
Adoptive Cell Therapy for Metastatic Melanoma
inferred← citeshttps://doi.org/10.1097/qai.0000000000001283openalex-snapshot
Granulocytic Myeloid–Derived Suppressor Cells Increased in Early Phases of Primary HIV Infection Depending on TRAIL Plasma Level
inferred← citeshttps://doi.org/10.1098/rsob.170006openalex-snapshot
Tuning cancer fate: the unremitting role of host immunity
inferred← citeshttps://doi.org/10.1101/2023.04.20.537647openalex-snapshot
Metabolic Reprogramming via targeting ACOD1 promotes polarization and anti-tumor activity of human CAR-iMACs in solid tumors
inferred← citeshttps://doi.org/10.1101/gad.169029.111openalex-snapshot
Immune microenvironments in solid tumors: new targets for therapy
inferred← citeshttps://doi.org/10.1111/acel.12571openalex-snapshot
Expansion of myeloid-derived suppressor cells with aging in the bone marrow of mice through a NF-κB-dependent mechanism
inferred← citeshttps://doi.org/10.1111/imm.12036openalex-snapshot
The immunosuppressive tumour network: myeloid‐derived suppressor cells, regulatory T cells and natural killer T cells
inferred← citeshttps://doi.org/10.1111/imr.12125openalex-snapshot
Of CAR s and TRUCK s: chimeric antigen receptor ( CAR ) T cells engineered with an inducible cytokine to modulate the tumor stroma
inferred← citeshttps://doi.org/10.1111/imr.13176openalex-snapshot
N1 versus N2 and PMN‐MDSC: A critical appraisal of current concepts on tumor‐associated neutrophils and new directions for human oncology
inferred← citeshttps://doi.org/10.1111/joim.12229openalex-snapshot
Tumour‐induced immune suppression: role of inflammatory mediators released by myelomonocytic cells
inferred← citeshttps://doi.org/10.1124/pr.111.004846openalex-snapshot
Synthetic Oleanane Triterpenoids: Multifunctional Drugs with a Broad Range of Applications for Prevention and Treatment of Chronic Disease
inferred← citeshttps://doi.org/10.1126/scitranslmed.3004306openalex-snapshot
The Stoichiometric Production of IL-2 and IFN-γ mRNA Defines Memory T Cells That Can Self-Renew After Adoptive Transfer in Humans
inferred← citeshttps://doi.org/10.1126/scitranslmed.add1868openalex-snapshot
FcγRIIB expressed on CD8+T cells limits responsiveness to PD-1 checkpoint inhibition in cancer
inferred← citeshttps://doi.org/10.1136/jitc-2023-008081openalex-snapshot
Fibrinogen-like protein 2 promotes tumor immune suppression by regulating cholesterol metabolism in myeloid-derived suppressor cells
inferred← citeshttps://doi.org/10.1137/23m1593061openalex-snapshot
Mathematical Modeling and Solution Landscape Reveal Cancer Progression Dynamics in Tumor Ecological Microenvironment
inferred← citeshttps://doi.org/10.1146/annurev-cancerbio-042120-105240openalex-snapshot
Myeloid-Derived Suppressor Cells: Facilitators of Cancer and Obesity-Induced Cancer
inferred← citeshttps://doi.org/10.1146/annurev-med-051013-052304openalex-snapshot
Regulation of Tumor Metastasis by Myeloid-Derived Suppressor Cells
inferred← citeshttps://doi.org/10.1146/annurev-pathmechdis-032221-115501openalex-snapshot
Innate Immunity and Cancer Pathophysiology
inferred← citeshttps://doi.org/10.1152/ajpcell.00834.2025openalex-snapshot
Tumor-associated macrophages: orchestrators of the tumor microenvironment
inferred← citeshttps://doi.org/10.1155/2016/9720912openalex-snapshot
New Mechanisms of Tumor-Associated Macrophages on Promoting Tumor Progression: Recent Research Advances and Potential Targets for Tumor Immunotherapy
inferred← citeshttps://doi.org/10.1155/2018/6728474openalex-snapshot
Corrigendum to “New Mechanisms of Tumor-Associated Macrophages on Promoting Tumor Progression: Recent Research Advances and Potential Targets for Tumor Immunotherapy”
inferred← citeshttps://doi.org/10.1158/0008-5472.can-11-3850openalex-snapshot
Therapeutic Efficacy of Bifunctional siRNA Combining TGF-β1 Silencing with RIG-I Activation in Pancreatic Cancer
inferred← citeshttps://doi.org/10.1158/0008-5472.can-12-3913openalex-snapshot
Simultaneous Targeting of Tumor Antigens and the Tumor Vasculature Using T Lymphocyte Transfer Synergize to Induce Regression of Established Tumors in Mice
inferred← citeshttps://doi.org/10.1158/0008-5472.can-12-3932openalex-snapshot
Tumor-Specific Cytotoxic T Cells Are Crucial for Efficacy of Immunomodulatory Antibodies in Patients with Lung Cancer
inferred← citeshttps://doi.org/10.1158/0008-5472.can-13-0987openalex-snapshot
Enhancement of Antitumor Immunity in Lung Cancer by Targeting Myeloid-Derived Suppressor Cell Pathways
inferred← citeshttps://doi.org/10.1158/0008-5472.can-13-1550openalex-snapshot
Therapeutic PD-1 Pathway Blockade Augments with Other Modalities of Immunotherapy T-Cell Function to Prevent Immune Decline in Ovarian Cancer
inferred← citeshttps://doi.org/10.1158/0008-5472.can-14-0473openalex-snapshot
Vaccine-Elicited CD8+ T Cells Cure Mesothelioma by Overcoming Tumor-Induced Immunosuppressive Environment
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