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Serrapeptase and nattokinase intervention for relieving Alzheimer’s disease pathophysiology in rat model

https://doi.org/10.1177/0960327112467040
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Mechanism of Amyloid Removal in Patients With Alzheimer Disease Treated With Gantenerumab
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Dying neural cells activate glia through the release of a protease product
inferredcites →https://doi.org/10.1002/eji.200838549openalex-snapshot
The Nlrp3 inflammasome is critical for aluminium hydroxide‐mediated IL‐1β secretion but dispensable for adjuvant activity
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Aluminum: Impacts and Disease
inferredcites →https://doi.org/10.1007/978-1-4419-8997-0_14openalex-snapshot
Oxidative Stress and Aging
inferredcites →https://doi.org/10.1007/bf01729833openalex-snapshot
Interleukin-6 in clinical medicine
inferredcites →https://doi.org/10.1007/bf01956052openalex-snapshot
A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet
inferredcites →https://doi.org/10.1007/pl00000630openalex-snapshot
Oxidative stress and hypoxia-like injury cause Alzheimer-type molecular abnormalities in central nervous system neurons
inferredcites →https://doi.org/10.1007/s00018-007-7288-3openalex-snapshot
Trypsin and trypsin-like proteases in the brain: Proteolysis and cellular functions
inferredcites →https://doi.org/10.1007/s11064-005-6960-yopenalex-snapshot
The Role of Neurotrophins in Brain Aging: A Perspective in Honor of Regino Perez-Polo
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Effect of Long-Term Exposure to Aluminum on the Acetylcholinesterase Activity in the Central Nervous System and Erythrocytes
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The nerve growth factor family
inferredcites →https://doi.org/10.1016/j.brainresrev.2003.08.007openalex-snapshot
Fas ligand/Fas system in the brain: regulator of immune and apoptotic responses
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2010.10.698openalex-snapshot
4-O-Methylhonokiol attenuates memory impairment in presenilin 2 mutant mice through reduction of oxidative damage and inactivation of astrocytes and the ERK pathway
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Cardioprotective effect of grape seed proanthocyanidins on isoproterenol-induced myocardial injury in rats
inferredcites →https://doi.org/10.1016/j.ijom.2007.11.011openalex-snapshot
Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus after surgical extraction of mandibular third molars
inferredcites →https://doi.org/10.1016/j.imlet.2007.09.002openalex-snapshot
Altered plasma cytokine levels in Alzheimer's disease: Correlation with the disease progression
inferredcites →https://doi.org/10.1016/j.jinorgbio.2005.04.021openalex-snapshot
Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture
inferredcites →https://doi.org/10.1016/j.jpsychires.2006.01.014openalex-snapshot
BDNF serum and CSF concentrations in Alzheimer’s disease, normal pressure hydrocephalus and healthy controls
inferredcites →https://doi.org/10.1016/j.mrgentox.2008.08.007openalex-snapshot
Developmental and genetic toxicity of stannous chloride in mouse dams and fetuses
inferredcites →https://doi.org/10.1016/j.nbd.2004.11.006openalex-snapshot
Amyloid-β peptide triggers Fas-independent apoptosis and differentiation of neural progenitor cells
inferredcites →https://doi.org/10.1016/j.nbd.2008.12.007openalex-snapshot
Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway
inferredcites →https://doi.org/10.1016/j.neulet.2007.10.025openalex-snapshot
TGF-β1 is increased in a transgenic mouse model of familial Alzheimer's disease and causes neuronal apoptosis
inferredcites →https://doi.org/10.1016/j.nutres.2009.01.009openalex-snapshot
Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects
inferredcites →https://doi.org/10.1016/j.phrs.2003.11.006openalex-snapshot
Protective effect of l-cysteine and glutathione on the modulated suckling rat brain Na+,K+-ATPase and Mg2+-ATPase activities induced by the in vitro galactosaemia
inferredcites →https://doi.org/10.1016/j.tox.2008.10.009openalex-snapshot
Susceptibility of mitochondrial superoxide dismutase to aluminium induced oxidative damage
inferredcites →https://doi.org/10.1016/s0006-8993(00)03176-0openalex-snapshot
β-Amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology
inferredcites →https://doi.org/10.1016/s0014-5793(98)00562-6openalex-snapshot
Oxidative stress and hypoxia/reoxygenation trigger CD95 (APO‐1/Fas) ligand expression in microglial cells
inferredcites →https://doi.org/10.1016/s0021-9258(19)52451-6openalex-snapshot
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
inferredcites →https://doi.org/10.1016/s0024-3205(03)00426-0openalex-snapshot
Dietary supplementation of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery
inferredcites →https://doi.org/10.1016/s0047-6374(02)00188-4openalex-snapshot
Preliminary studies on Alzheimer's disease using cDNA microarrays
inferredcites →https://doi.org/10.1016/s0165-5728(00)00321-0openalex-snapshot
Hydrogen peroxide triggers the expression of Fas/FasL in astrocytoma cell lines and augments apoptosis
inferredcites →https://doi.org/10.1016/s0165-5728(03)00158-9openalex-snapshot
Interleukin-6, β-amyloid peptide and NMDA interactions in rat cortical neurons
inferredcites →https://doi.org/10.1016/s0168-0102(02)00201-8openalex-snapshot
Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide
inferredcites →https://doi.org/10.1016/s0168-8278(98)80145-1openalex-snapshot
Serum levels of soluble Fas antigen in chronic hepatitis C patients
inferredcites →https://doi.org/10.1016/s0197-4580(01)00306-2openalex-snapshot
Gene expression profiling of amyloid beta peptide-stimulated human post-mortem brain microglia
inferredcites →https://doi.org/10.1016/s0268-9499(95)80005-0openalex-snapshot
Characterization of nattokinase-degraded products from human fibrinogen or cross-linked fibrin
inferredcites →https://doi.org/10.1016/s0748-5514(86)80066-6openalex-snapshot
Intracellular proteolytic systems may function as secondary antioxidant defenses: An hypothesis
inferredcites →https://doi.org/10.1016/s0968-0004(00)89100-8openalex-snapshot
Defective protein folding as a basis of human disease
inferredcites →https://doi.org/10.1021/jf000020kopenalex-snapshot
Potent Fibrinolytic Enzyme from a Mutant of Bacillus subtilis IMR-NK1
inferredcites →https://doi.org/10.1021/jf803072ropenalex-snapshot
Amyloid-Degrading Ability of Nattokinase from Bacillus subtilis Natto
inferredcites →https://doi.org/10.1038/nm1202-793openalex-snapshot
Serum insulin-like growth factor I regulates brain amyloid-β levels
inferredcites →https://doi.org/10.1038/nm793openalex-snapshot
Serum insulin-like growth factor I regulates brain amyloid-β levels
inferredcites →https://doi.org/10.1038/nrg1111openalex-snapshot
Human and mouse proteases: a comparative genomic approach
inferredcites →https://doi.org/10.1042/0264-6021:3430371openalex-snapshot
Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein
inferredcites →https://doi.org/10.1046/j.1440-1843.2003.00482.xopenalex-snapshot
Effect of the proteolytic enzyme serrapeptase in patients with chronic airway disease
inferredcites →https://doi.org/10.1046/j.1471-4159.2000.0752133.xopenalex-snapshot
Coordinated Expression of β‐Amyloid Precursor Protein and the Putative β‐Secretase BACE and α‐Secretase ADAM10 in Mouse and Human Brain
inferredcites →https://doi.org/10.1073/pnas.081612998openalex-snapshot
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10
inferredcites →https://doi.org/10.1073/pnas.96.7.3922openalex-snapshot
Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease
inferredcites →https://doi.org/10.1074/jbc.m101751200openalex-snapshot
The Profibrinolytic Enzyme Subtilisin NAT Purified fromBacillus subtilis Cleaves and Inactivates Plasminogen Activator Inhibitor Type 1
inferredcites →https://doi.org/10.1091/mbc.e07-08-0811openalex-snapshot
Neuronal Death by Oxidative Stress Involves Activation of FOXO3 through a Two-Arm Pathway That Activates Stress Kinases and Attenuates Insulin-like Growth Factor I Signaling
inferredcites →https://doi.org/10.1093/clinchem/43.10.1965openalex-snapshot
Immunological measurement of transforming growth factor-beta 1 (TGF-β1) in blood; assay development and comparison
inferredcites →https://doi.org/10.1101/pdb.prot065789openalex-snapshot
Two-Photon Imaging of Neural Networks in a Mouse Model of Alzheimer’s Disease
inferredcites →https://doi.org/10.1126/science.181.4096.223openalex-snapshot
Principles that Govern the Folding of Protein Chains
inferredcites →https://doi.org/10.1146/annurev.biochem.68.1.1015openalex-snapshot
The 26S Proteasome: A Molecular Machine Designed for Controlled Proteolysis
inferredcites →https://doi.org/10.1172/jci20864openalex-snapshot
A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model
inferredcites →https://doi.org/10.1177/030006059001800506openalex-snapshot
Evaluation of Serratia Peptidase in Acute or Chronic Inflammation of Otorhinolaryngology Pathology: A Multicentre, Double-Blind, Randomized Trial versus Placebo
inferredcites →https://doi.org/10.1186/1742-2094-1-11openalex-snapshot
Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised.
inferredcites →https://doi.org/10.1210/en.133.4.1797openalex-snapshot
Bioavailability of insulin-like growth factors (IGFs) in rats determined by the molecular distribution of human IGF-binding protein-3
inferredcites →https://doi.org/10.1289/ehp.30-1637724openalex-snapshot
Experimental study of biological effects of leads and aluminum following oral administration
inferredcites →https://doi.org/10.1385/mn:29:2:167openalex-snapshot
Hydrogen Peroxide As a Diffusible Signal Molecule in Synaptic Plasticity
inferredcites →https://doi.org/10.1523/jneurosci.20-01-00149.2000openalex-snapshot
Neuronal–Glial Interactions Mediated by Interleukin-1 Enhance Neuronal Acetylcholinesterase Activity and mRNA Expression
inferredcites →https://doi.org/10.1523/jneurosci.21-19-07551.2001openalex-snapshot
Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.
inferredcites →https://doi.org/10.15537/1658-3175.4740openalex-snapshot
Berberine and total base from rhizoma coptis chinensis attenuate brain injury in an aluminum-induced rat model of neurodegenerative disease
inferredcites →https://doi.org/10.2106/00004623-200606000-00006openalex-snapshot
THE EFFECT OF PROTEOLYTIC ENZYME SERRATIOPEPTIDASE IN THE TREATMENT OF EXPERIMENTAL IMPLANT-RELATED INFECTION
inferredcites →https://doi.org/10.2146/ajhp050509openalex-snapshot
Nattokinase for prevention of thrombosis
inferredcites →https://doi.org/10.2165/0002512-200926020-00005openalex-snapshot
Diagnosis and Treatment of Patients with Severe Alzheimer’s Disease
inferredcites →https://doi.org/10.2165/00044011-200019010-00003openalex-snapshot
Short-Term Treatment of Painful Osteoarthritis of the Knee with Oral Enzymes
inferredcites →https://doi.org/10.2174/1381612053381620openalex-snapshot
Inflammatory Process in Parkinsons Disease: Role for Cytokines
inferredcites →https://doi.org/10.3233/jad-2004-6304openalex-snapshot
Alzheimer-associated neuronal thread protein mediated cell death is linked to impaired insulin signaling
inferredcites →https://doi.org/10.4049/jimmunol.181.10.7254openalex-snapshot
Fibrillar Amyloid-β Peptides Activate Microglia via TLR2: Implications for Alzheimer’s Disease
inferredcites →https://doi.org/10.4314/ajb.v7i10.58688openalex-snapshot
Effect of water pollution on expression of immune response genes of Solea aegyptiaca in Lake Qarun

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4111083openalex-extracted
Protective Effects of Nattokinase Against Microvascular Abnormalities and Neuroinflammation by Regulating HMGB1 Signaling in Diabetic Retinopathy
inferred← citeshttps://doi.org/10.1007/978-1-4939-0956-8_13openalex-snapshot
Pharmacogenomics of Alzheimer’s Disease: Novel Therapeutic Strategies for Drug Development
inferred← citeshttps://doi.org/10.1007/s00203-024-03889-6openalex-snapshot
An up-to-date review of biomedical applications of serratiopeptidase and its biobetter derivatives as a multi-potential metalloprotease
inferred← citeshttps://doi.org/10.1007/s00253-014-6135-3openalex-snapshot
Nattokinase: production and application
inferred← citeshttps://doi.org/10.1007/s00253-022-12356-5openalex-snapshot
Serrapeptase impairs biofilm, wall, and phospho-homeostasis of resistant and susceptible Staphylococcus aureus
inferred← citeshttps://doi.org/10.1007/s00253-023-12772-1openalex-snapshot
In vitro and in silico evaluation of the serrapeptase effect on biofilm and amyloids of Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1007/s00394-022-02937-5openalex-snapshot
Soy product intake and risk of incident disabling dementia: the JPHC Disabling Dementia Study
inferred← citeshttps://doi.org/10.1007/s10719-015-9620-8openalex-snapshot
Interactions between nattokinase and heparin/GAGs
inferred← citeshttps://doi.org/10.1007/s10787-025-01641-0openalex-snapshot
Uncovering the intricacies of IGF-1 in Alzheimer’s disease: new insights from regulation to therapeutic targeting
inferred← citeshttps://doi.org/10.1007/s10930-021-10023-8openalex-snapshot
Fibrinolytic and ACE Inhibitory Activity of Nattokinase Extracted from Bacillus subtilis VITMS 2: A Strain Isolated from Fermented Milk of Vigna unguiculata
inferred← citeshttps://doi.org/10.1007/s11356-022-21126-9openalex-snapshot
Nattokinase attenuates bisphenol A or gamma irradiation-mediated hepatic and neural toxicity by activation of Nrf2 and suppression of inflammatory mediators in rats
inferred← citeshttps://doi.org/10.1007/s11515-017-1461-3openalex-snapshot
Production, purification, characterization, immobilization, and application of Serrapeptase: a review
inferred← citeshttps://doi.org/10.1007/s12011-021-03083-5openalex-snapshot
Centella asiatica Alleviates AlCl3-induced Cognitive Impairment, Oxidative Stress, and Neurodegeneration by Modulating Cholinergic Activity and Oxidative Burden in Rat Brain
inferred← citeshttps://doi.org/10.1007/s12035-024-04457-1openalex-snapshot
Insulin-Like Growth Factor Signaling in Alzheimer’s Disease: Pathophysiology and Therapeutic Strategies
inferred← citeshttps://doi.org/10.1007/s13596-018-0331-0openalex-snapshot
Focalization of thrombosis and therapeutic perspectives: a memoir
inferred← citeshttps://doi.org/10.1016/b978-0-12-821039-0.00012-5openalex-snapshot
Importance of fermented foods on human health
inferred← citeshttps://doi.org/10.1016/b978-0-12-823506-5.00018-7openalex-snapshot
Production of fibrinolytic enzymes during food production
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102308openalex-snapshot
The significance of precisely regulating heme oxygenase-1 expression: Another avenue for treating age-related ocular disease?
inferred← citeshttps://doi.org/10.1016/j.bcab.2022.102564openalex-snapshot
Nattokinase: Structure, applications and sources
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118362openalex-snapshot
Eriocitrin and its derivatives against Alzheimer’s disease: Cumulative accounts of in vitro and in vivo studies
inferred← citeshttps://doi.org/10.1016/j.brainres.2016.04.022openalex-snapshot
Protective effect of transient receptor potential vanilloid subtype 1 (TRPV1) modulator, against behavioral, biochemical and structural damage in experimental models of Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.brainres.2024.149352openalex-snapshot
“Nattokinase as a potential therapeutic agent for preventing blood-brain barrier dysfunction in neurodegenerative disorders”
inferred← citeshttps://doi.org/10.1016/j.btre.2020.e00544openalex-snapshot
Serratiopeptidase: Insights into the therapeutic applications
inferred← citeshttps://doi.org/10.1016/j.crbiot.2025.100316openalex-snapshot
Multifaceted microbial enzyme nattokinase: a comprehensive review on therapeutics applications, production technologies and intellectual property landscape
inferred← citeshttps://doi.org/10.1016/j.ejphar.2017.09.043openalex-snapshot
The present and future of pharmacotherapy of Alzheimer’s disease: A comprehensive review
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Vascular Necrosis of the Upper Extremity After Self-Treatment for Peyronie's Disease
inferred← citeshttps://doi.org/10.1016/j.fshw.2023.02.042openalex-snapshot
Degradation of amyloid β-peptides catalyzed by nattokinase in vivo and in vitro
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e26849openalex-snapshot
Development of novel natto using legumes produced in Europe
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.07.303openalex-snapshot
Purification, physicochemical properties, and statistical optimization of fibrinolytic enzymes especially from fermented foods: A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.jff.2020.104251openalex-snapshot
Nattokinase mitigated dextran sulfate sodium-induced chronic colitis by regulating microbiota and suppressing tryptophan metabolism via inhibiting IDO-1
inferred← citeshttps://doi.org/10.1016/j.jrras.2025.101660openalex-snapshot
Magnetized water mitigates AlCl3-induced oxidative stress and Alzheimer's-like neurotoxicity in rats
inferred← citeshttps://doi.org/10.1016/j.jtemb.2021.126902openalex-snapshot
Aluminum inhibits non-amyloid pathways via retinoic acid receptor
inferred← citeshttps://doi.org/10.1016/j.msec.2018.07.025openalex-snapshot
Co-delivery of curcumin and serratiopeptidase in HeLa and MCF-7 cells through nanoparticles show improved anti-cancer activity
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2022.104896openalex-snapshot
Protective role of IGF-1 and GLP-1 signaling activation in neurological dysfunctions
inferred← citeshttps://doi.org/10.1016/j.pharma.2024.05.008openalex-snapshot
Advances and challenges in serratiopeptidase topical formulation
inferred← citeshttps://doi.org/10.1016/j.toxrep.2020.06.001openalex-snapshot
Exploiting Citrus aurantium seeds and their secondary metabolites in the management of Alzheimer disease
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c08718openalex-snapshot
Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin
inferred← citeshttps://doi.org/10.1051/wujns/2026312166openalex-snapshot
Advances in Nattokinase Research: Therapeutic Potential and Applications
inferred← citeshttps://doi.org/10.1080/10408398.2021.1910481openalex-snapshot
Phosphocalcic metabolism and the role of vitamin D, vitamin K2, and nattokinase supplementation
inferred← citeshttps://doi.org/10.1080/10408398.2022.2134980openalex-snapshot
Production, purification, and functional properties of microbial fibrinolytic enzymes produced by microorganism obtained from soy-based fermented foods: developments and challenges
inferred← citeshttps://doi.org/10.1080/2314808x.2022.2139114openalex-snapshot
Centella asiatica L. Urban protects against cognitive dysfunction in alluminum chloride-induced neurotoxicity in rats via inhibition of acetylcholinesterase level
inferred← citeshttps://doi.org/10.1111/1753-0407.13439openalex-snapshot
Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy
inferred← citeshttps://doi.org/10.1155/jdr/5519447openalex-snapshot
ADAM9 Genetic Variants and Their Role in Modulating Enzyme Activity in Diabetes and Metabolic Traits
inferred← citeshttps://doi.org/10.1167/iovs.62.6.25openalex-snapshot
Nattokinase Attenuates Retinal Neovascularization Via Modulation of Nrf2/HO-1 and Glial Activation
inferred← citeshttps://doi.org/10.1177/1177271918785130openalex-snapshot
Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases
inferred← citeshttps://doi.org/10.1177/1934578x251332132openalex-snapshot
Nattokinase Mitigates Myocardial Damage and Renal Dysfunction in γ-Irradiated Rats Treated with Isoproterenol
inferred← citeshttps://doi.org/10.1186/1550-2783-11-27openalex-snapshot
Effect of an herbal/botanical supplement on recovery from delayed onset muscle soreness: a randomized placebo-controlled trial
inferred← citeshttps://doi.org/10.1186/s40360-021-00506-wopenalex-snapshot
Safety assessment of subtilisin QK in rats
inferred← citeshttps://doi.org/10.12677/ojns.2024.122034openalex-snapshot
Research Progress in Nattokinase and Its Pharmacology
inferred← citeshttps://doi.org/10.1371/journal.pone.0155733openalex-snapshot
Meta-Analysis of Serum Insulin-Like Growth Factor 1 in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.18174/647603openalex-snapshot
Microbial thiamine production : Harnessing the power of microbes for meaty aromas
inferred← citeshttps://doi.org/10.20961/jthp.v16i1.72623openalex-snapshot
Kajian Enzim Fibrinolitik pada Mikroorganisme Asal Pangan Fermentasi Asia: Review
inferred← citeshttps://doi.org/10.2174/1574888x18666230523155659openalex-snapshot
Conditioned Media Therapy in Alzheimer's Disease: Current Findings and Future Challenges
inferred← citeshttps://doi.org/10.21873/invivo.13744openalex-snapshot
Effect of Nattokinase in D-galactose- and Aluminum Chloride-induced Alzheimer’s Disease Model of Rat
inferred← citeshttps://doi.org/10.22141/pjs.14.3.2024.432openalex-snapshot
Perspectives for using serratiopeptidase in systemic enzyme therapy for low-intensity chronic inflammation and pain syndromes: from mechanisms of action to practical implementation (literature review)
inferred← citeshttps://doi.org/10.23880/act-16000205openalex-snapshot
Potential of the Combination of a Systemic Enzyme Complex and Probiotics administration to Combat COVID-19: A Randomized Open Label Prospective Analysis
inferred← citeshttps://doi.org/10.26599/fshw.2022.9250198openalex-snapshot
Nattokinase as a functional food ingredient: therapeutic applications and mechanisms in age-related diseases
inferred← citeshttps://doi.org/10.3233/jad-190837openalex-snapshot
Bacillus Subtilis Delays Neurodegeneration and Behavioral Impairment in the Alzheimer’s Disease Model Caenorhabditis Elegans
inferred← citeshttps://doi.org/10.3389/fimmu.2021.582556openalex-snapshot
Nutraceutical Approach to Preventing Coronavirus Disease 2019 and Related Complications
inferred← citeshttps://doi.org/10.3389/fphar.2021.603997openalex-snapshot
Serratiopeptidase, A Serine Protease Anti-Inflammatory, Fibrinolytic, and Mucolytic Drug, Can Be a Useful Adjuvant for Management in COVID-19
inferred← citeshttps://doi.org/10.3390/biom12070980openalex-snapshot
Biotechnology, Bioengineering and Applications of Bacillus Nattokinase
inferred← citeshttps://doi.org/10.3390/cimb45030142openalex-snapshot
Serratiopeptidase Attenuates Lipopolysaccharide-Induced Vascular Inflammation by Inhibiting the Expression of Monocyte Chemoattractant Protein-1
inferred← citeshttps://doi.org/10.3390/fermentation8070307openalex-snapshot
Enhanced Production Process of Recombinant Mature Serratiopeptidase in Escherichia coli Using Fed-Batch Culture by Self-Proteolytic Activity of Fusion Protein
inferred← citeshttps://doi.org/10.3390/fermentation9110950openalex-snapshot
Nattokinase: Insights into Biological Activity, Therapeutic Applications, and the Influence of Microbial Fermentation
inferred← citeshttps://doi.org/10.3390/foods10112779openalex-snapshot
Changes in Functionality of Germinated and Non-Germinated Brown Rice Fermented by Bacillus natto
inferred← citeshttps://doi.org/10.3390/foods11131867openalex-snapshot
Recent Advances in Nattokinase-Enriched Fermented Soybean Foods: A Review
inferred← citeshttps://doi.org/10.3390/foods14203482openalex-snapshot
Optimization of EPA-Nattokinase Nanoemulsions Processed by High-Pressure Homogenization to Enhance Stability and Thrombolytic Efficacy
inferred← citeshttps://doi.org/10.3390/ijms18030523openalex-snapshot
Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease
inferred← citeshttps://doi.org/10.3390/ijms21207790openalex-snapshot
An Overview of ADAM9: Structure, Activation, and Regulation in Human Diseases
inferred← citeshttps://doi.org/10.3390/life13112196openalex-snapshot
Fibrin and Fibrinolytic Enzyme Cascade in Thrombosis: Unravelling the Role
inferred← citeshttps://doi.org/10.3390/nu13062031openalex-snapshot
Data Recorded in Real Life Support the Safety of Nattokinase in Patients with Vascular Diseases
inferred← citeshttps://doi.org/10.3390/pharmaceutics13111880openalex-snapshot
Microbial Fibrinolytic Enzymes as Anti-Thrombotics: Production, Characterisation and Prodigious Biopharmaceutical Applications
inferred← citeshttps://doi.org/10.3390/pharmaceutics15051386openalex-snapshot
Germanium Dioxide Nanoparticles Mitigate Biochemical and Molecular Changes Characterizing Alzheimer’s Disease in Rats
inferred← citeshttps://doi.org/10.4014/jmb.1812.12058openalex-snapshot
Nattokinase Crude Extract Inhibits Hepatocellular Carcinoma Growth in Mice
inferred← citeshttps://doi.org/10.4236/aer.2021.91001openalex-snapshot
Analysis of Main Components and Prospects of Natto
inferred← citeshttps://doi.org/10.6084/m9.figshare.14850622openalex-snapshot
Additional file 1 of Safety assessment of subtilisin QK in rats
inferred← citeshttps://doi.org/10.62767/jecacm504.6557openalex-snapshot
Automated, Microscopic Measurement of Fibrinaloid Microclots and Their Degradation by Nattokinase, the Main Natto Protease
inferred← citeshttps://doi.org/10.71217/uju.2(6).2025.53-69openalex-snapshot
SYSTEMIC ENZYME THERAPY DRUGS IN THE TREATMENT OF PATIENTS WITH CHRONIC INFLAMMATORY DISEASES OF THE MALE GENITAL ORGANS
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