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Effects of low- and high-frequency electroacupuncture on protein expression and distribution of TRPV1 and P2X3 in rats with peripheral nerve injury

https://doi.org/10.1177/0964528420968845
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cne.24302openalex-snapshot
The reduction of intraepidermal P2X3 nerve fiber density correlates with behavioral hyperalgesia in a rat model of nerve injury‐induced pain
inferredcites →https://doi.org/10.1002/jnr.23451openalex-snapshot
Electroacupuncture and A‐317491 depress the transmission of pain on primary afferent mediated by the P2X3 receptor in rats with chronic neuropathic pain states
inferredcites →https://doi.org/10.1007/978-1-61779-561-9_15openalex-snapshot
The Spared Nerve Injury Model of Neuropathic Pain
inferredcites →https://doi.org/10.1007/s00221-002-1263-xopenalex-snapshot
Alteration of dorsal root ganglion P2X 3 receptor expression and function following spinal nerve ligation in the rat
inferredcites →https://doi.org/10.1007/s11302-015-9447-6openalex-snapshot
Effect of electroacupuncture on P2X3 receptor regulation in the peripheral and central nervous systems of rats with visceral pain caused by irritable bowel syndrome
inferredcites →https://doi.org/10.1007/s11302-015-9481-4openalex-snapshot
Differential expression of ATP-gated P2X receptors in DRG between chronic neuropathic pain and visceralgia rat models
inferredcites →https://doi.org/10.1016/0165-0270(94)90144-9openalex-snapshot
Quantitative assessment of tactile allodynia in the rat paw
inferredcites →https://doi.org/10.1016/j.brainresbull.2008.02.026openalex-snapshot
Effect of tetramethylpyrazine on primary afferent transmission mediated by P2X3 receptor in neuropathic pain states
inferredcites →https://doi.org/10.1016/j.ejphar.2014.11.039openalex-snapshot
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain
inferredcites →https://doi.org/10.1016/j.expneurol.2007.09.004openalex-snapshot
Long-term synaptic plasticity in the spinal dorsal horn and its modulation by electroacupuncture in rats with neuropathic pain
inferredcites →https://doi.org/10.1016/j.jneumeth.2011.04.036openalex-snapshot
Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats
inferredcites →https://doi.org/10.1016/j.lfs.2016.06.025openalex-snapshot
Electroacupuncture analgesia with different frequencies is mediated via different opioid pathways in acute visceral hyperalgesia rats
inferredcites →https://doi.org/10.1016/j.lfs.2018.03.028openalex-snapshot
Parameter-specific analgesic effects of electroacupuncture mediated by degree of regulation TRPV1 and P2X3 in inflammatory pain in rats
inferredcites →https://doi.org/10.1016/j.neuroscience.2012.11.015openalex-snapshot
P2X3 and TRPV1 functionally interact and mediate sensitization of trigeminal sensory neurons
inferredcites →https://doi.org/10.1016/j.pain.2005.09.007openalex-snapshot
Mechanisms underlying enhanced P2X receptor-mediated responses in the neuropathic pain state
inferredcites →https://doi.org/10.1016/j.pain.2009.01.006openalex-snapshot
Cross-inhibition between native and recombinant TRPV1 and P2X3 receptors
inferredcites →https://doi.org/10.1016/j.pain.2009.04.013openalex-snapshot
Differential regulation of TRP channels in a rat model of neuropathic pain
inferredcites →https://doi.org/10.1016/j.pain.2013.11.013openalex-snapshot
Neuropathic pain in the general population: A systematic review of epidemiological studies
inferredcites →https://doi.org/10.1016/j.pneurobio.2008.05.004openalex-snapshot
Neural mechanism underlying acupuncture analgesia
inferredcites →https://doi.org/10.1016/s0304-3940(02)01302-2openalex-snapshot
Changes in the gene expression of six subtypes of P2X receptors in rat dorsal root ganglion after spinal nerve ligation
inferredcites →https://doi.org/10.1016/s0304-3959(00)00276-1openalex-snapshot
Spared nerve injury: an animal model of persistent peripheral neuropathic pain
inferredcites →https://doi.org/10.1016/s0304-3959(02)00067-2openalex-snapshot
VR1, but not P2X3, increases in the spared L4 DRG in rats with L5 spinal nerve ligation
inferredcites →https://doi.org/10.1016/s0304-3959(02)00261-0openalex-snapshot
The effect of high and low frequency electroacupuncture in pain after lower abdominal surgery
inferredcites →https://doi.org/10.1016/s1474-4422(14)70251-0openalex-snapshot
Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis
inferredcites →https://doi.org/10.1038/srep42531openalex-snapshot
Electroacupuncture Attenuates CFA-induced Inflammatory Pain by suppressing Nav1.8 through S100B, TRPV1, Opioid, and Adenosine Pathways in Mice
inferredcites →https://doi.org/10.1046/j.0953-816x.2001.01591.xopenalex-snapshot
VR1 protein expression increases in undamaged DRG neurons after partial nerve injury
inferredcites →https://doi.org/10.1046/j.1460-9568.2003.02504.xopenalex-snapshot
Selective increase of tumour necrosis factor‐alpha in injured and spared myelinated primary afferents after chronic constrictive injury of rat sciatic nerve
inferredcites →https://doi.org/10.1089/acm.2011.0914openalex-snapshot
Factors Associated with Conflicting Findings on Acupuncture for Tension-Type Headache: Qualitative and Quantitative Analyses
inferredcites →https://doi.org/10.1097/aap.0b013e318203087fopenalex-snapshot
Mechanical Hypersensitivity, Sympathetic Sprouting, and Glial Activation Are Attenuated by Local Injection of Corticosteroid Near the Lumbar Ganglion in a Rat Model of Neuropathic Pain
inferredcites →https://doi.org/10.1097/aln.0000000000000101openalex-snapshot
Mechanisms of Acupuncture–Electroacupuncture on Persistent Pain
inferredcites →https://doi.org/10.1136/acupmed-2013-010324openalex-snapshot
An Exploratory Review of the Electroacupuncture Literature: Clinical Applications and Endorphin Mechanisms
inferredcites →https://doi.org/10.1136/acupmed-2015-010951openalex-snapshot
Electroacupuncture Relieves Labour Pain and Influences the Spinal Dynorphin/κ-Opioid Receptor System in Rats
inferredcites →https://doi.org/10.1152/ajpgi.00180.2013openalex-snapshot
Combined genetic and pharmacological inhibition of TRPV1 and P2X3 attenuates colorectal hypersensitivity and afferent sensitization
inferredcites →https://doi.org/10.1155/2013/170910openalex-snapshot
Low Frequency Electroacupuncture Alleviated Spinal Nerve Ligation Induced Mechanical Allodynia by Inhibiting TRPV1 Upregulation in Ipsilateral Undamaged Dorsal Root Ganglia in Rats
inferredcites →https://doi.org/10.1155/2014/129875openalex-snapshot
Effect of Electroacupuncture on Rats with Chronic Constriction Injury-Induced Neuropathic Pain
inferredcites →https://doi.org/10.1177/1099800418804896openalex-snapshot
Beneficial Effects of Electroacupuncture on Neuropathic Pain Evoked by Spinal Cord Injury and Involvement of PI3K-mTOR Mechanisms
inferredcites →https://doi.org/10.1186/1744-8069-9-13openalex-snapshot
Intervention of Electroacupuncture on Spinal p38 MAPK/ATF-2/VR-1 Pathway in Treating Inflammatory Pain Induced by CFA in Rats
inferredcites →https://doi.org/10.1213/ane.0b013e318246536dopenalex-snapshot
The Effects of Electroacupuncture at the ST36 (Zusanli) Acupoint on Cancer Pain and Transient Receptor Potential Vanilloid Subfamily 1 Expression in Walker 256 Tumor-Bearing Rats
inferredcites →https://doi.org/10.1213/ane.0b013e31826f0a4aopenalex-snapshot
The Effects of Electroacupuncture on the Extracellular Signal-Regulated Kinase 1/2/P2X3 Signal Pathway in the Spinal Cord of Rats with Chronic Constriction Injury
inferredcites →https://doi.org/10.1590/0004-282x20180128openalex-snapshot
Involvement of adenosine A1 receptor in electroacupuncture-mediated inhibition of astrocyte activation during neuropathic pain
inferredcites →https://doi.org/10.2217/pmt-2018-0052openalex-snapshot
Nonopioid Versus Opioid Agents for Chronic Neuropathic Pain, Rheumatoid Arthritis Pain, Cancer Pain and Low Back Pain
inferredcites →https://doi.org/10.3109/00207454.2014.922559openalex-snapshot
Surgical animal models of neuropathic pain: Pros and Cons
inferredcites →https://doi.org/10.3349/ymj.2007.48.1.41openalex-snapshot
Antiallodynic Effect of Pregabalin in Rat Models of Sympathetically Maintained and Sympathetic Independent Neuropathic Pain

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4093994openalex-extracted
The Role of Spinal RIP3 in Inflammatory Pain and Electroacupuncture-Mediated Analgesic Effect in Mice
inferred← citeshttps://doi.org/10.2139/ssrn.4673416openalex-extracted
Key Targets of Signal Transduction Neural Mechanisms in Acupuncture Treatment of Cardiovascular Diseases: Hypothalamus and Autonomic Nervous System
inferred← citeshttps://doi.org/10.1007/s11302-024-09985-yopenalex-snapshot
The role of purinergic signaling in acupuncture-mediated relief of neuropathic and inflammatory pain
inferred← citeshttps://doi.org/10.1016/j.ctmp.2024.200149openalex-snapshot
Different genes involved in the amelioration of chronic neuropathic pain and comorbid anxiety by electroacupuncture with different intensities
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e38197openalex-snapshot
Key targets of signal transduction neural mechanisms in acupuncture treatment of cardiovascular diseases: Hypothalamus and autonomic nervous system
inferred← citeshttps://doi.org/10.1016/j.joim.2026.07.005openalex-snapshot
Low-frequency electroacupuncture alleviates neuropathic pain via cannabinoid receptor type 2 signaling in the spinal cord dorsal horn
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.120839openalex-snapshot
Role of spinal RIP3 in inflammatory pain and electroacupuncture-mediated analgesic effect in mice
inferred← citeshttps://doi.org/10.1016/j.lfs.2024.122954openalex-snapshot
Current insights and therapeutic strategies for targeting TRPV1 in neuropathic pain management
inferred← citeshttps://doi.org/10.1016/j.neurom.2022.07.009openalex-snapshot
Spinal Sirtuin 3 Contributes to Electroacupuncture Analgesia in Mice With Chronic Constriction Injury–Induced Neuropathic Pain
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2021.12.017openalex-snapshot
Electroacupuncture Pretreatment Attenuates Cerebral Ischemia-Reperfusion Injury in Rats Through Transient Receptor Potential Vanilloid 1-Mediated Anti-apoptosis via Inhibiting NF-κB Signaling Pathway
inferred← citeshttps://doi.org/10.1016/j.pmn.2026.04.021openalex-snapshot
Research Advances in Acupuncture Treatment for Chronic Pain
inferred← citeshttps://doi.org/10.1016/j.wjam.2023.05.002openalex-snapshot
Role of transient receptor potential vanilloid subfamily 1 in mediating the analgesic effects of acupuncture on pathological pain
inferred← citeshttps://doi.org/10.1101/2025.01.23.633455openalex-snapshot
Lipid nanoparticle delivery of siRNA to dorsal root ganglion neurons to treat pain
inferred← citeshttps://doi.org/10.1111/jcmm.18240openalex-snapshot
Electroacupuncture suppresses neuronal ferroptosis to relieve chronic neuropathic pain
inferred← citeshttps://doi.org/10.1155/2022/1489841openalex-snapshot
Electroacupuncture Alleviates Neuropathic Pain through Regulating miR-206-3p Targeting BDNF after CCI
inferred← citeshttps://doi.org/10.1177/09645284241279874openalex-snapshot
Electroacupuncture inhibits TLR4/NF-κB signaling in the dorsal root ganglion of rats with spared nerve injury
inferred← citeshttps://doi.org/10.1186/s13256-026-06027-6openalex-snapshot
Electroacupuncture for the treatment of infraorbital nerve injury caused by zygomaticomaxillary complex fracture: a case report
inferred← citeshttps://doi.org/10.21203/rs.3.rs-657177/v1openalex-snapshot
Electroacupuncture Pretreatment Attenuates Cerebral Ischemia-Reperfusion Injury through Transient Receptor Potential Vanilloid 1-Mediated Anti-Apoptosis via Inhibiting NF-kB Signaling Pathway
inferred← citeshttps://doi.org/10.2147/jpr.s357435openalex-snapshot
Efficacy of Electroacupuncture for the Treatment of Postherpetic Neuralgia: Study Protocol for a Multicenter Randomized Controlled Trial
inferred← citeshttps://doi.org/10.3389/fmed.2025.1616035openalex-snapshot
The efficacy of electroacupuncture for postherpetic neuralgia arising from herpes zoster affecting the cephalo-facial area: study protocol for a double center randomized controlled trial
inferred← citeshttps://doi.org/10.3389/fmed.2026.1924469openalex-snapshot
Efficacy and safety of 2 Hz versus 100 Hz electroacupuncture for pain-dominant shoulder periarthritis: a study protocol for a single-center randomized controlled trial
inferred← citeshttps://doi.org/10.3389/fneur.2023.1093849openalex-snapshot
Role of nerve signal transduction and neuroimmune crosstalk in mediating the analgesic effects of acupuncture for neuropathic pain
inferred← citeshttps://doi.org/10.3389/fnins.2021.636348openalex-snapshot
Neuregulin1-ErbB4 Signaling in Spinal Cord Participates in Electroacupuncture Analgesia in Inflammatory Pain
inferred← citeshttps://doi.org/10.3389/fnins.2022.940343openalex-snapshot
Potential mechanisms of acupuncture for neuropathic pain based on somatosensory system
inferred← citeshttps://doi.org/10.3389/fnmol.2022.974007openalex-snapshot
Shared nociceptive dorsal root ganglion neurons participating in acupoint sensitization
inferred← citeshttps://doi.org/10.3389/fphar.2021.593043openalex-snapshot
Phosphoproteomic Profiling of Rat’s Dorsal Root Ganglia Reveals mTOR as a Potential Target in Bone Cancer Pain and Electro-Acupuncture’s Analgesia
inferred← citeshttps://doi.org/10.3389/fphar.2021.680198openalex-snapshot
Increasing Efficiency of Repetitive Electroacupuncture on Purine- and Acid-Induced Pain During a Three-Week Treatment Schedule
inferred← citeshttps://doi.org/10.3390/ani14060884openalex-snapshot
Early Intensive Neurorehabilitation in Traumatic Peripheral Nerve Injury—State of the Art
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