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Li-Fraumeni Syndrome
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1 of the 179 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1158/0008-5472.can-04-1145 (notice 2019-04-15).
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/jama.296.22.2727openalex-snapshot
Preimplantation Genetic Diagnosis for Cancer Syndromes
inferredcites →https://doi.org/10.1001/jama.299.11.1315openalex-snapshot
F18-Fluorodeoxyglucose–Positron Emission Tomography/Computed Tomography Screening in Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1002/(sici)1097-0142(19970801)80:3+<569::aid-cncr6>3.0.co;2-4openalex-snapshot
Psychologic aspects of cancer genetic testing
inferredcites →https://doi.org/10.1002/cncr.22834openalex-snapshot
Telomere length in peripheral blood cells of germline TP53 mutation carriers is shorter than that of normal individuals of corresponding age
inferredcites →https://doi.org/10.1002/cncr.26377openalex-snapshot
Early onset HER2‐positive breast cancer is associated with germline TP53 mutations
inferredcites →https://doi.org/10.1002/gepi.1370120103openalex-snapshot
ARCAD: A method for estimating age‐dependent disease risk associated with mutation carrier status from family data
inferredcites →https://doi.org/10.1002/humu.10136openalex-snapshot
Increasing evidence that germline mutations inCHEK2do not cause Li-Fraumeni syndrome
inferredcites →https://doi.org/10.1002/humu.10185openalex-snapshot
GermlineTP53 mutations and Li-Fraumeni syndrome
inferredcites →https://doi.org/10.1002/humu.10218openalex-snapshot
Germline TP53 Mutations and Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1002/humu.20495openalex-snapshot
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database
inferredcites →https://doi.org/10.1002/humu.21151openalex-snapshot
Detailed haplotype analysis at the TP53 locus in p.R337H mutation carriers in the population of Southern Brazil: evidence for a founder effect
inferredcites →https://doi.org/10.1002/ijc.1021openalex-snapshot
Two metachronous tumors in the radiotherapy fields of a patient with Li‐Fraumeni syndrome
inferredcites →https://doi.org/10.1002/j.1460-2075.1990.tb08279.xopenalex-snapshot
Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form.
inferredcites →https://doi.org/10.1002/pbc.21836openalex-snapshot
Early detection of adrenocortical carcinoma in a child with Li–Fraumeni syndrome
inferredcites →https://doi.org/10.1002/pon.1352openalex-snapshot
Psychological functioning in persons considering genetic counseling and testing for Li–Fraumeni syndrome
inferredcites →https://doi.org/10.1002/pon.1951openalex-snapshot
Distress in partners of individuals diagnosed with or at high risk of developing tumors due to rare hereditary cancer syndromes
inferredcites →https://doi.org/10.1002/pon.933openalex-snapshot
Psychological impact of genetic testing for cancer susceptibility: an update of the literature
inferredcites →https://doi.org/10.1006/jmbi.1998.1897openalex-snapshot
In vitro analysis of the dominant negative effect of p53 mutants
inferredcites →https://doi.org/10.1006/scbi.1996.0035openalex-snapshot
The p53-deficient mouse: a model for basic and applied cancer studies
inferredcites →https://doi.org/10.1007/s000180050271openalex-snapshot
Covalent and noncovalent modifiers of the p53 protein
inferredcites →https://doi.org/10.1007/s00439-005-0016-xopenalex-snapshot
Generation or birth cohort effect on cancer risk in Li–Fraumeni syndrome
inferredcites →https://doi.org/10.1007/s00439-011-0957-1openalex-snapshot
Joint effects of germ-line TP53 mutation, MDM2 SNP309, and gender on cancer risk in family studies of Li–Fraumeni syndrome
inferredcites →https://doi.org/10.1007/s00439-011-1039-0openalex-snapshot
Sex-specific effect of the TP53 PIN3 polymorphism on cancer risk in a cohort study of TP53 germline mutation carriers
inferredcites →https://doi.org/10.1007/s100380200055openalex-snapshot
Is there anticipation in the age at onset of cancer in families with Li-Fraumeni syndrome?
inferredcites →https://doi.org/10.1007/s10495-009-0330-1openalex-snapshot
Targeting p53 for enhanced radio- and chemo-sensitivity
inferredcites →https://doi.org/10.1007/s10689-004-1946-5openalex-snapshot
The TP53 mutational spectrum and frequency of CHEK2*1100delC in Li–Fraumeni-like kindreds
inferredcites →https://doi.org/10.1007/s10689-009-9245-9openalex-snapshot
Childhood predictive genetic testing for Li–Fraumeni syndrome
inferredcites →https://doi.org/10.1007/s10689-009-9265-5openalex-snapshot
Attitude towards pre-implantation genetic diagnosis for hereditary cancer
inferredcites →https://doi.org/10.1007/s10689-010-9368-zopenalex-snapshot
Regular surveillance for Li-fraumeni syndrome: advice, adherence and perceived benefits
inferredcites →https://doi.org/10.1007/s10689-012-9557-zopenalex-snapshot
Routine TP53 testing for breast cancer under age 30: ready for prime time?
inferredcites →https://doi.org/10.1016/0092-8674(79)90293-9openalex-snapshot
Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
inferredcites →https://doi.org/10.1016/0092-8674(91)90384-bopenalex-snapshot
Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation
inferredcites →https://doi.org/10.1016/j.ajhg.2010.10.007openalex-snapshot
A Common Molecular Mechanism Underlies Two Phenotypically Distinct 17p13.1 Microdeletion Syndromes
inferredcites →https://doi.org/10.1016/j.cancergencyto.2009.04.014openalex-snapshot
The TP53 gene promoter is not methylated in families suggestive of Li-Fraumeni syndrome with no germline TP53 mutations
inferredcites →https://doi.org/10.1016/j.canlet.2005.12.039openalex-snapshot
The TP53 mutation, R337H, is associated with Li-Fraumeni and Li-Fraumeni-like syndromes in Brazilian families
inferredcites →https://doi.org/10.1016/j.canlet.2007.10.044openalex-snapshot
Detection of R337H, a germline TP53 mutation predisposing to multiple cancers, in asymptomatic women participating in a breast cancer screening program in Southern Brazil
inferredcites →https://doi.org/10.1016/j.cell.2004.11.004openalex-snapshot
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1016/j.cell.2004.11.006openalex-snapshot
Gain of Function of a p53 Hot Spot Mutation in a Mouse Model of Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1016/j.cell.2004.11.022openalex-snapshot
A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans
inferredcites →https://doi.org/10.1016/j.cell.2011.12.013openalex-snapshot
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
inferredcites →https://doi.org/10.1016/j.ejca.2005.01.026openalex-snapshot
Identification of five new families strengthens the link between childhood choroid plexus carcinoma and germline TP53 mutations
inferredcites →https://doi.org/10.1016/j.ejca.2005.11.032openalex-snapshot
BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives
inferredcites →https://doi.org/10.1016/j.mce.2011.09.010openalex-snapshot
Towards an understanding of the role of p53 in adrenocortical carcinogenesis
inferredcites →https://doi.org/10.1016/j.semradonc.2010.08.008openalex-snapshot
Radiotherapy in the Treatment of Hereditary Breast Cancer
inferredcites →https://doi.org/10.1016/s0002-9440(10)64194-6openalex-snapshot
Variable Levels of Chromosomal Instability and Mitotic Spindle Checkpoint Defects in Breast Cancer
inferredcites →https://doi.org/10.1016/s0002-9440(10)64853-5openalex-snapshot
Development of Spontaneous Mammary Tumors in BALB/c p53 Heterozygous Mice
inferredcites →https://doi.org/10.1016/s0039-6060(03)00410-0openalex-snapshot
Androgen-secreting adrenal tumors
inferredcites →https://doi.org/10.1016/s0140-6736(00)02347-3openalex-snapshot
Presymptomatic DNA testing and prophylactic surgery in families with a BRCA1 or BRCA2 mutation
inferredcites →https://doi.org/10.1016/s0140-6736(03)12856-5openalex-snapshot
Prediction of pathogenic mutations in patients with early-onset breast cancer by family history
inferredcites →https://doi.org/10.1016/s0165-4608(00)00303-4openalex-snapshot
Identification of a novel PTEN intronic deletion in Li-Fraumeni syndrome and its effect on RNA processing
inferredcites →https://doi.org/10.1016/s0304-3835(99)00291-8openalex-snapshot
Analysis of Li–Fraumeni syndrome and Li–Fraumeni-like families for germline mutations in Bcl10
inferredcites →https://doi.org/10.1016/s0960-9822(00)00002-6openalex-snapshot
Tumor spectrum analysis in p53-mutant mice
inferredcites →https://doi.org/10.1016/s1097-2765(00)80002-7openalex-snapshot
Is a p53-Regulated Inhibitor of G2/M Progression
inferredcites →https://doi.org/10.1016/s1470-2045(09)70089-0openalex-snapshot
Highly prevalent TP53 mutation predisposing to many cancers in the Brazilian population: a case for newborn screening?
inferredcites →https://doi.org/10.1016/s1470-2045(11)70119-xopenalex-snapshot
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study
inferredcites →https://doi.org/10.1016/s1472-6483(10)61953-0openalex-snapshot
Celebrating preimplantation genetic diagnosis of p53 mutations in Li-Fraumeni syndrome
inferredcites →https://doi.org/10.1038/278261a0openalex-snapshot
T antigen is bound to a host protein in SY40-transformed cells
inferredcites →https://doi.org/10.1038/35160openalex-snapshot
Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c
inferredcites →https://doi.org/10.1038/356215a0openalex-snapshot
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
inferredcites →https://doi.org/10.1038/358080a0openalex-snapshot
Amplification of a gene encoding a p53-associated protein in human sarcomas
inferredcites →https://doi.org/10.1038/358083a0openalex-snapshot
Wild-type p53 activates transcription in vitro
inferredcites →https://doi.org/10.1038/bjc.1995.390openalex-snapshot
A possible screening test for inherited p53-related defects based on the apoptotic response of peripheral blood lymphocytes to DNA damage
inferredcites →https://doi.org/10.1038/bjc.1998.364openalex-snapshot
Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families
inferredcites →https://doi.org/10.1038/ejhg.2009.25openalex-snapshot
Genetic testing in asymptomatic minors
inferredcites →https://doi.org/10.1038/ejhg.2009.26openalex-snapshot
Genetic testing in asymptomatic minors: recommendations of the European Society of Human Genetics
inferredcites →https://doi.org/10.1038/ng1093-124openalex-snapshot
Screening patients for heterozygous p53 mutations using a functional assay in yeast
inferredcites →https://doi.org/10.1038/ng1097-141openalex-snapshot
KILLER/DR5 is a DNA damage–inducible p53–regulated death receptor gene
inferredcites →https://doi.org/10.1038/ng1193-225openalex-snapshot
Spontaneous and carcinogen–induced tumorigenesis in p53–deficient mice
inferredcites →https://doi.org/10.1038/ng1282openalex-snapshot
Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice
inferredcites →https://doi.org/10.1038/ng879openalex-snapshot
Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations
inferredcites →https://doi.org/10.1038/nm0495-302openalex-snapshot
Testing for cancer genes: Decisions, decisions
inferredcites →https://doi.org/10.1038/nrc1235openalex-snapshot
Comparative biology of mouse versus human cells: modelling human cancer in mice
inferredcites →https://doi.org/10.1038/nsb730openalex-snapshot
A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer
inferredcites →https://doi.org/10.1038/sj.bjc.6690313openalex-snapshot
Exclusion of the genes CDKN2 and PTEN as causative gene defects in Li–Fraumeni syndrome
inferredcites →https://doi.org/10.1038/sj.ejhg.5201715openalex-snapshot
The single-nucleotide polymorphism 309 in the MDM2 gene contributes to the Li–Fraumeni syndrome and related phenotypes
inferredcites →https://doi.org/10.1038/sj.onc.1201041openalex-snapshot
A detailed study of loss of heterozygosity on chromosome 17 in tumours from Li – Fraumeni patients carrying a mutation to the TP53 gene
inferredcites →https://doi.org/10.1038/sj.onc.1201050openalex-snapshot
Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations
inferredcites →https://doi.org/10.1038/sj.onc.1202033openalex-snapshot
Cancer phenotype correlates with constitutional TP53 genotype in families with the Li–Fraumeni syndrome
inferredcites →https://doi.org/10.1038/sj.onc.1202667openalex-snapshot
Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45
inferredcites →https://doi.org/10.1038/sj.onc.1202783openalex-snapshot
p53 compound heterozygosity in a severely affected child with Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1038/sj.onc.1204369openalex-snapshot
Characterization of germline TP53 splicing mutations and their genetic and functional analysis
inferredcites →https://doi.org/10.1038/sj.onc.1204373openalex-snapshot
The role of tetramerization in p53 function
inferredcites →https://doi.org/10.1038/sj.onc.1204621openalex-snapshot
Relative frequency and morphology of cancers in carriers of germline TP53 mutations
inferredcites →https://doi.org/10.1038/sj.onc.1206155openalex-snapshot
Screening for TP53 rearrangements in families with the Li–Fraumeni syndrome reveals a complete deletion of the TP53 gene
inferredcites →https://doi.org/10.1038/sj.onc.1207396openalex-snapshot
Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes
inferredcites →https://doi.org/10.1038/sj.onc.1209877openalex-snapshot
The CHEK2 gene and inherited breast cancer susceptibility
inferredcites →https://doi.org/10.1053/j.gastro.2005.10.014openalex-snapshot
Prevalence of Early Onset Colorectal Cancer in 397 Patients With Classic Li–Fraumeni Syndrome
inferredcites →https://doi.org/10.1056/nejm199205143262002openalex-snapshot
Germline Mutations of the p53 Tumor-Suppressor Gene in Children and Young Adults with Second Malignant Neoplasms
inferredcites →https://doi.org/10.1056/nejm199209243271309openalex-snapshot
Preimplantation Genetic Diagnosis
inferredcites →https://doi.org/10.1067/msy.2003.145openalex-snapshot
Cystosarcoma phyllodes (phyllodes tumor) of the male breast
inferredcites →https://doi.org/10.1073/pnas.0802970105openalex-snapshot
Excessive genomic DNA copy number variation in the Li–Fraumeni cancer predisposition syndrome
inferredcites →https://doi.org/10.1073/pnas.1431692100openalex-snapshot
Understanding the function–structure and function–mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis
inferredcites →https://doi.org/10.1073/pnas.161479898openalex-snapshot
An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma
inferredcites →https://doi.org/10.1073/pnas.68.4.820openalex-snapshot
Mutation and Cancer: Statistical Study of Retinoblastoma
inferredcites →https://doi.org/10.1073/pnas.76.5.2420openalex-snapshot
Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse.
inferredcites →https://doi.org/10.1073/pnas.83.1.130openalex-snapshot
The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13).
inferredcites →https://doi.org/10.1073/pnas.89.14.6413openalex-snapshot
Germ-line mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein.
inferredcites →https://doi.org/10.1073/pnas.92.9.3963openalex-snapshot
A simple p53 functional assay for screening cell lines, blood, and tumors.
inferredcites →https://doi.org/10.1073/pnas.97.8.4174openalex-snapshot
High metastatic potential in mice inheriting a targeted p53 missense mutation
inferredcites →https://doi.org/10.1080/095530096145139openalex-snapshot
Fibroblasts from Li-Fraumeni patients are resistant to low dose-rate irradiation
inferredcites →https://doi.org/10.1084/jem.188.11.2033openalex-snapshot
p53 Activates the CD95 (APO-1/Fas) Gene in Response to DNA Damage by Anticancer Drugs
inferredcites →https://doi.org/10.1086/341943openalex-snapshot
A CHEK2 Genetic Variant Contributing to a Substantial Fraction of Familial Breast Cancer
inferredcites →https://doi.org/10.1086/374567openalex-snapshot
Germline p53 Mutations in a Cohort with Childhood Sarcoma: Sex Differences in Cancer Risk
inferredcites →https://doi.org/10.1093/carcin/bgn044openalex-snapshot
Constitutional CHEK2 mutations are associated with a decreased risk of lung and laryngeal cancers
inferredcites →https://doi.org/10.1093/emboj/17.16.4657openalex-snapshot
Retention of wild‐type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation
inferredcites →https://doi.org/10.1093/jnci/43.6.1365openalex-snapshot
Rhabdomyosarcoma in Children: Epidemiologic Study and Identification of a Familial Caneer Syndrome
inferredcites →https://doi.org/10.1093/jnci/84.15.1156openalex-snapshot
Recommendations on Predictive Testing for Germ Line p53 Mutations Among Cancer-Prone Individuals
inferredcites →https://doi.org/10.1093/jnci/90.8.606openalex-snapshot
Multiple Primary Cancers in Families With Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1093/jncimonographs/lgi027openalex-snapshot
Preimplantation Genetic Diagnosis (PGD) for Heritable Neoplasia
inferredcites →https://doi.org/10.1093/pch/8.1.42openalex-snapshot
Guidelines for genetic testing of healthy children
inferredcites →https://doi.org/10.1097/00003086-200208000-00011openalex-snapshot
Genetics of Childhood Cancer
inferredcites →https://doi.org/10.1097/01.gim.0000214632.52958.01openalex-snapshot
Evaluation of a decision aid for families considering p53 genetic counseling and testing
inferredcites →https://doi.org/10.1097/01.mph.0000140650.65591.f1openalex-snapshot
Predictive Genetic Testing for Childhood Cancer: Taking the Road Less Traveled By
inferredcites →https://doi.org/10.1097/yco.0b013e3283252d80openalex-snapshot
Psychosocial aspects of genetic testing
inferredcites →https://doi.org/10.1126/science.1589764openalex-snapshot
Oncogenic Forms of p53 Inhibit p53-Regulated Gene Expression
inferredcites →https://doi.org/10.1126/science.1978757openalex-snapshot
Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms
inferredcites →https://doi.org/10.1126/science.2047879openalex-snapshot
Identification of p53 as a Sequence-Specific DNA-Binding Protein
inferredcites →https://doi.org/10.1126/science.252.5007.827openalex-snapshot
Ultradeep (>300 Kilometers) Ultramafic Xenoliths: Petrological Evidence from the Transition Zone
inferredcites →https://doi.org/10.1126/science.2649981openalex-snapshot
Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas
inferredcites →https://doi.org/10.1126/science.278.5340.1043openalex-snapshot
Human Cancer Syndromes: Clues to the Origin and Nature of Cancer
inferredcites →https://doi.org/10.1126/science.286.5449.2528openalex-snapshot
Heterozygous Germ Line hCHK2 Mutations in Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1126/science.289.5478.357popenalex-snapshot
Screening hCHK2 for Mutations
inferredcites →https://doi.org/10.1126/science.289.5478.359aopenalex-snapshot
Screening hCHK2 for Mutations
inferredcites →https://doi.org/10.1128/jvi.62.10.3903-3906.1988openalex-snapshot
Two distinct regions of the murine p53 primary amino acid sequence are implicated in stable complex formation with simian virus 40 T antigen
inferredcites →https://doi.org/10.1128/mcb.17.1.460openalex-snapshot
Proteolytic Cleavage of Human p53 by Calpain: a Potential Regulator of Protein Stability
inferredcites →https://doi.org/10.1128/mcb.21.17.5869-5878.2001openalex-snapshot
c-Abl Regulates p53 Levels under Normal and Stress Conditions by Preventing Its Nuclear Export and Ubiquitination
inferredcites →https://doi.org/10.1128/mcb.8.1.461openalex-snapshot
Phosphorylation of p53 in Normal and Simian Virus 40-Transformed NIH 3T3 Cells
inferredcites →https://doi.org/10.1128/mcb.9.9.3982openalex-snapshot
High Incidence of Lung, Bone, and Lymphoid Tumors in Transgenic Mice Overexpressing Mutant Alleles of the p53 Oncogene
inferredcites →https://doi.org/10.1136/bmj.314.7078.441openalex-snapshot
Who should talk to patients with cancer about genetics?
inferredcites →https://doi.org/10.1136/jmg.2004.030551openalex-snapshot
Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation
inferredcites →https://doi.org/10.1136/jmg.2005.037952openalex-snapshot
Impact of the MDM2 SNP309 and p53 Arg72Pro polymorphism on age of tumour onset in Li-Fraumeni syndrome
inferredcites →https://doi.org/10.1136/jmg.2008.057570openalex-snapshot
Molecular basis of the Li–Fraumeni syndrome: an update from the French LFS families
inferredcites →https://doi.org/10.1136/jmg.2008.058958openalex-snapshot
High frequency of de novo mutations in Li–Fraumeni syndrome
inferredcites →https://doi.org/10.1136/jmg.2008.064972openalex-snapshot
Predictive diagnosis of the cancer prone Li–Fraumeni syndrome by accident: new challenges through whole genome array testing
inferredcites →https://doi.org/10.1136/jmg.2009.066704openalex-snapshot
TP53 PIN3 and MDM2 SNP309 polymorphisms as genetic modifiers in the Li–Fraumeni syndrome: impact on age at first diagnosis
inferredcites →https://doi.org/10.1136/jmg.2010.078113openalex-snapshot
A novel HER2-positive breast cancer phenotype arising from germline TP53 mutations: Table 1
inferredcites →https://doi.org/10.1136/jmg.34.9.746openalex-snapshot
Uptake of genetic testing for cancer predisposition.
inferredcites →https://doi.org/10.1136/jmg.37.8.e13openalex-snapshot
Absence of germline p16 INK4a alterations in p53 wild type Li-Fraumeni syndrome families
inferredcites →https://doi.org/10.1136/jmg.38.1.43openalex-snapshot
Sensitivity and predictive value of criteria for p53germline mutation screening
inferredcites →https://doi.org/10.1136/jmg.38.4.253openalex-snapshot
Detection of 11 germline inactivating TP53 mutations and absence of TP63 andHCHK2 mutations in 17 French families with Li-Fraumeni or Li-Fraumeni-like syndrome
inferredcites →https://doi.org/10.1136/jmg.39.11.833openalex-snapshot
Genetic testing in hereditary non-polyposis colorectal cancer families with a MSH2, MLH1, or MSH6 mutation
inferredcites →https://doi.org/10.1146/annurev.genom.3.032802.120023openalex-snapshot
M OLECULAR M ECHANISMS FOR G ENOMIC D ISORDERS
inferredcites →https://doi.org/10.1155/2012/786930openalex-snapshot
Genetic Testing for Minors: Comparison between Italian and British Guidelines
inferredcites →https://doi.org/10.1158/0008-5472.427.65.2openalex-snapshot
Genetic Mapping of a Third Li-Fraumeni Syndrome Predisposition Locus to Human Chromosome 1q23
inferredcites →https://doi.org/10.1158/0008-5472.can-04-1145openalex-snapshot
Transactivation of the EGR1 Gene Contributes to Mutant p53 Gain of Function
inferredcites →https://doi.org/10.1158/0008-5472.can-05-0825openalex-snapshot
A Single Nucleotide Polymorphism in the MDM2 Gene: From a Molecular and Cellular Explanation to Clinical Effect
inferredcites →https://doi.org/10.1158/0008-5472.can-05-4247openalex-snapshot
Joint Effects of Germ-Line p53 Mutation and Sex on Cancer Risk in Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1158/0008-5472.can-06-0180openalex-snapshot
MDM2 SNP309 Accelerates Tumor Formation in a Gender-Specific and Hormone-Dependent Manner
inferredcites →https://doi.org/10.1158/0008-5472.can-06-3682openalex-snapshot
Younger Age of Cancer Initiation Is Associated with Shorter Telomere Length in Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1158/0008-5472.can-09-0851openalex-snapshot
Population-Based Estimate of the Contribution of TP53 Mutations to Subgroups of Early-Onset Breast Cancer: Australian Breast Cancer Family Study
inferredcites →https://doi.org/10.1158/1055-9965.1403.13.8openalex-snapshot
Germ Line BAX Alterations Are Infrequent in Li-Fraumeni Syndrome
inferredcites →https://doi.org/10.1182/blood.v87.10.4376.bloodjournal87104376openalex-snapshot
The p53 gene in pediatric therapy-related leukemia and myelodysplasia
inferredcites →https://doi.org/10.1186/1748-717x-5-104openalex-snapshot
Radio-induced malignancies after breast cancer postoperative radiotherapy in patients with Li-Fraumeni syndrome
inferredcites →https://doi.org/10.1186/1897-4287-7-4openalex-snapshot
The contribution of CHEK2 to the TP53-negative Li-Fraumeni phenotype
inferredcites →https://doi.org/10.1200/jco.1996.14.5.1730openalex-snapshot
Statement of the American Society of Clinical Oncology: genetic testing for cancer susceptibility, Adopted on February 20, 1996.
inferredcites →https://doi.org/10.1200/jco.2000.18.10.2135openalex-snapshot
Anticipated Versus Actual Emotional Reactions to Disclosure of Results of Genetic Tests for Cancer Susceptibility: Findings From p53 and BRCA1 Testing Programs
inferredcites →https://doi.org/10.1200/jco.2003.03.189openalex-snapshot
American Society of Clinical Oncology Policy Statement Update: Genetic Testing for Cancer Susceptibility
inferredcites →https://doi.org/10.1200/jco.2007.12.5922openalex-snapshot
CHEK2*1100delC Genotyping for Clinical Assessment of Breast Cancer Risk: Meta-Analyses of 26,000 Patient Cases and 27,000 Controls
inferredcites →https://doi.org/10.1200/jco.2008.16.6959openalex-snapshot
Beyond Li Fraumeni Syndrome: Clinical Characteristics of Families With p53 Germline Mutations
inferredcites →https://doi.org/10.1200/jco.2008.21.2712openalex-snapshot
Professionals Assess the Acceptability of Preimplantation Genetic Diagnosis and Prenatal Diagnosis for Managing Inherited Predisposition to Cancer
inferredcites →https://doi.org/10.1200/jco.2009.22.7967openalex-snapshot
2009 Version of the Chompret Criteria for Li Fraumeni Syndrome
inferredcites →https://doi.org/10.1200/jco.2009.23.9855openalex-snapshot
Prenatal Diagnosis, Preimplantation Genetic Diagnosis, and Cancer: Was Hamlet Wrong?
inferredcites →https://doi.org/10.1200/jco.2009.27.2112openalex-snapshot
Genetic Testing in Li-Fraumeni Syndrome: Uptake and Psychosocial Consequences
inferredcites →https://doi.org/10.1200/jco.2015.63.0996openalex-snapshot
American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility
inferredcites →https://doi.org/10.1371/journal.pone.0010813openalex-snapshot
Effects of MDM2, MDM4 and TP53 Codon 72 Polymorphisms on Cancer Risk in a Cohort Study of Carriers of TP53 Germline Mutations
inferredcites →https://doi.org/10.1542/peds.107.6.1451openalex-snapshot
Ethical Issues With Genetic Testing in Pediatrics
inferredcites →https://doi.org/10.1590/s0004-27302004000500009openalex-snapshot
Founder effect for the highly prevalent R337H mutation of tumor suppressor p53 in Brazilian patients with adrenocortical tumors
inferredcites →https://doi.org/10.1667/0033-7587(2002)157[0158:dccigi]2.0.co;2openalex-snapshot
Delayed Chromosome Changes in Gamma-Irradiated Normal and Li-Fraumeni Fibroblasts
inferredcites →https://doi.org/10.18632/aging.100498openalex-snapshot
Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice
inferredcites →https://doi.org/10.2165/00024669-200504040-00008openalex-snapshot
American Society of Clinical Oncology
inferredcites →https://doi.org/10.2217/14796694.4.6.759openalex-snapshot
Potential of Advexin ® : A p53 Gene-Replacement Therapy in Li–Fraumeni Syndrome
inferredcites →https://doi.org/10.3343/kjlm.2008.28.6.493openalex-snapshot
Genetic Counseling Can Influence the Course of a Suspected Familial Cancer Syndrome Patient: From a Case of Li-Fraumeni Like Syndrome with a Germline Mutation in the TP53 Gene
inferredcites →https://doi.org/10.7326/0003-4819-71-4-747openalex-snapshot
Soft-Tissue Sarcomas, Breast Cancer, and Other Neoplasms
inferredcites →https://doi.org/10.7326/0003-4819-88-5-725_6openalex-snapshot
Current Medical Diagnosis and Treatment.
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.3960702openalex-extracted
Cancer Surveillance for Patients with Li-Fraumeni Syndrome in Brazil is Cost-Effective
inferred← citeshttps://doi.org/10.1001/jamaoncol.2015.0197openalex-snapshot
GermlineTP53Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry
inferred← citeshttps://doi.org/10.1001/jamaoncol.2016.6389openalex-snapshot
Frequency of Thyroid Carcinoma in Brazilian TP53 p.R337H Carriers With Li Fraumeni Syndrome
inferred← citeshttps://doi.org/10.1002/9781118464557.ch67openalex-snapshot
Uncommon Adrenal Tumors in Children and Adolescents
inferred← citeshttps://doi.org/10.1002/9781118919408.ch1openalex-snapshot
Recent Development in Methodology for Gene Network Problems and Inferences
inferred← citeshttps://doi.org/10.1002/9781119000822.hfcm143openalex-snapshot
Hereditary Cancer Syndromes: Risk Assessment and Genetic Counseling
inferred← citeshttps://doi.org/10.1002/9781119000822.hfcm143.pub2openalex-snapshot
Hereditary Cancer Syndromes: Risk Assessment and Genetic Counseling
inferred← citeshttps://doi.org/10.1002/9781119196235.ch77openalex-snapshot
Uncommon Adrenal Tumors in Children and Adolescents
inferred← citeshttps://doi.org/10.1002/cam4.3427openalex-snapshot
Radiation therapy and secondary malignancy in Li‐Fraumeni syndrome: A hereditary cancer registry study
inferred← citeshttps://doi.org/10.1002/ccr3.2698openalex-snapshot
Breast cancer suspected to originate from familial hereditary tumors: A case report
inferred← citeshttps://doi.org/10.1002/cncr.30703openalex-snapshot
Contribution of the TP53 R337H mutation to the cancer burden in southern Brazil: Insights from the study of 55 families of children with adrenocortical tumors
inferred← citeshttps://doi.org/10.1002/cncr.33922openalex-snapshot
Subsequent malignant neoplasms in the Childhood Cancer Survivor Study: Occurrence of cancer types in which human papillomavirus is an established etiologic risk factor
inferred← citeshttps://doi.org/10.1002/emmm.201101105openalex-snapshot
Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes
inferred← citeshttps://doi.org/10.1002/gcc.22956openalex-snapshot
Single nucleotide polymorphism array‐based signature of low hypodiploidy in acute lymphoblastic leukemia
inferred← citeshttps://doi.org/10.1002/hed.24594openalex-snapshot
Li–Fraumeni syndrome presenting as mucosal melanoma: Case report and treatment considerations
inferred← citeshttps://doi.org/10.1002/humu.22254openalex-snapshot
Drastic Effect of GermlineTP53Missense Mutations in Li-Fraumeni Patients
inferred← citeshttps://doi.org/10.1002/humu.22507openalex-snapshot
Insights into Wild-Type and Mutant p53 Functions Provided by Genetically Engineered Mice
inferred← citeshttps://doi.org/10.1002/humu.22514openalex-snapshot
TP53 Mutants in the Tower of Babel of Cancer Progression
inferred← citeshttps://doi.org/10.1002/humu.23320openalex-snapshot
Higher-than-expected population prevalence of potentially pathogenic germlineTP53variants in individuals unselected for cancer history
inferred← citeshttps://doi.org/10.1002/mgg3.70177openalex-snapshot
Clinical Features and Treatment Strategies of Li‐Fraumeni Syndrome Patients With Inherited TP53 Mutations
inferred← citeshttps://doi.org/10.1002/pbc.20700openalex-snapshot
Malignant triton tumor in a patient with Li‐Fraumeni syndrome and a novel TP53 mutation
inferred← citeshttps://doi.org/10.1002/pbc.24269openalex-snapshot
The germline TP53 mutation c.722 C>T promotes bone and liver tumorigenesis at a young age
inferred← citeshttps://doi.org/10.1002/pbc.31487openalex-snapshot
A Unique Case of a Pediatric Patient with Six Childhood Cancers in Association with a Germline TP53 Gene Pathogenic Variant
inferred← citeshttps://doi.org/10.1002/wsbm.1342openalex-snapshot
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial
inferred← citeshttps://doi.org/10.1007/164_2017_55openalex-snapshot
Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4419-8044-1_2openalex-snapshot
DNA Damage Signaling Downstream of ATM
inferred← citeshttps://doi.org/10.1007/978-1-4614-5116-7_1openalex-snapshot
Epidemiology and Etiology of Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-3-030-03952-3_13openalex-snapshot
IER5 Is a p53-Regulated Activator of HSF1 That Contributes to Promotion of Cancer
inferred← citeshttps://doi.org/10.1007/978-3-030-66853-2_7openalex-snapshot
Genetic Predispositions and Prophylactic Mastectomy in Breast Cancer Patients
inferred← citeshttps://doi.org/10.1007/978-3-030-71113-9_3-1openalex-snapshot
Predisposing Genetic Variants and Potent Genetic Mutations in Cancer
inferred← citeshttps://doi.org/10.1007/978-3-030-74448-9_12openalex-snapshot
Inherited Pediatric Cancer in Low- and Intermediate-Resource Countries
inferred← citeshttps://doi.org/10.1007/978-3-030-94110-9_17openalex-snapshot
Role of Genetics in Gynaecological Cancers
inferred← citeshttps://doi.org/10.1007/978-3-031-23687-7_8openalex-snapshot
Pediatric Brain and Brainstem Tumors
inferred← citeshttps://doi.org/10.1007/978-3-031-23705-8_7openalex-snapshot
Tumors of Choroid Plexus and Other Ventricular Tumors
inferred← citeshttps://doi.org/10.1007/978-3-031-76882-8_3openalex-snapshot
Predisposing Genetic Variants and Potent Genetic Mutations in Cancer
inferred← citeshttps://doi.org/10.1007/978-3-319-28100-1_23-1openalex-snapshot
Non-Odontogenic Bone Pathology
inferred← citeshttps://doi.org/10.1007/978-3-319-28845-1_5222-1openalex-snapshot
Li-Fraumeni Syndrome
inferred← citeshttps://doi.org/10.1007/978-3-319-78762-6_9openalex-snapshot
P53 in Head and Neck Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.1007/978-3-642-56889-3_8openalex-snapshot
Hereditärer Brust- und Eierstockkrebs
inferred← citeshttps://doi.org/10.1007/978-3-662-48590-3_4openalex-snapshot
Screening for Genetic Susceptibility to Paediatric Tumours
inferred← citeshttps://doi.org/10.1007/978-94-017-9211-0_1openalex-snapshot
p53 and Hereditary Cancer
inferred← citeshttps://doi.org/10.1007/978-94-017-9421-3_4openalex-snapshot
p53 at the Crossroads Between Stress Response Signaling and Tumorigenesis: From Molecular Mechanisms to Therapeutic Opportunities
inferred← citeshttps://doi.org/10.1007/978-981-10-4726-8_2openalex-snapshot
Transcription Factors as Detection and Diagnostic Biomarkers in Cancer
inferred← citeshttps://doi.org/10.1007/978-981-15-6171-9_5openalex-snapshot
Molecular Mechanisms of Early Breast Cancer
inferred← citeshttps://doi.org/10.1007/s00204-019-02578-4openalex-snapshot
The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro
inferred← citeshttps://doi.org/10.1007/s00216-022-04388-7openalex-snapshot
Electrochemical biosensors for analysis of DNA point mutations in cancer research
inferred← citeshttps://doi.org/10.1007/s00292-017-0365-yopenalex-snapshot
Pathogenese und genetischer Hintergrund des Osteosarkoms
inferred← citeshttps://doi.org/10.1007/s00330-024-10983-2openalex-snapshot
Baseline surveillance in Li Fraumeni syndrome using whole-body MRI: a systematic review and updated meta-analysis
inferred← citeshttps://doi.org/10.1007/s00381-015-2868-2openalex-snapshot
Reply to: Familial syndromes associated with intracranial tumours: a review
inferred← citeshttps://doi.org/10.1007/s00381-023-06112-xopenalex-snapshot
Medulloblastomas, CNS embryonal tumors, and cerebellar mutism syndrome: advances in care and future directions
inferred← citeshttps://doi.org/10.1007/s00401-014-1348-1openalex-snapshot
Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors
inferred← citeshttps://doi.org/10.1007/s00439-017-1845-0openalex-snapshot
Expanding the spectrum of germline variants in cancer
inferred← citeshttps://doi.org/10.1007/s10549-014-3011-xopenalex-snapshot
Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer
inferred← citeshttps://doi.org/10.1007/s10549-017-4531-yopenalex-snapshot
Clinical implications of germline mutations in breast cancer: TP53
inferred← citeshttps://doi.org/10.1007/s10549-018-4938-0openalex-snapshot
A portrait of germline mutation in Brazilian at-risk for hereditary breast cancer
inferred← citeshttps://doi.org/10.1007/s10549-021-06410-5openalex-snapshot
Uptake and timing of bilateral and contralateral risk-reducing mastectomy in women with Li–Fraumeni syndrome
inferred← citeshttps://doi.org/10.1007/s10689-010-9368-zopenalex-snapshot
Regular surveillance for Li-fraumeni syndrome: advice, adherence and perceived benefits
inferred← citeshttps://doi.org/10.1007/s10689-012-9557-zopenalex-snapshot
Routine TP53 testing for breast cancer under age 30: ready for prime time?
inferred← citeshttps://doi.org/10.1007/s10689-013-9667-2openalex-snapshot
The MDM2 285G–309G haplotype is associated with an earlier age of tumour onset in patients with Li-Fraumeni syndrome
inferred← citeshttps://doi.org/10.1007/s10689-014-9754-zopenalex-snapshot
Further evidence for pathogenicity of the TP53 tetramerization domain mutation p.Arg342Pro in Li–Fraumeni syndrome
inferred← citeshttps://doi.org/10.1007/s10689-016-9895-3openalex-snapshot
Evaluation of TP53 Pro72Arg and MDM2 SNP285–SNP309 polymorphisms in an Italian cohort of LFS suggestive patients lacking identifiable TP53 germline mutations
inferred← citeshttps://doi.org/10.1007/s10689-016-9935-zopenalex-snapshot
TP53 and CDKN1A mutation analysis in families with Li–Fraumeni and Li–Fraumeni like syndromes
inferred← citeshttps://doi.org/10.1007/s10689-016-9943-zopenalex-snapshot
Uptake of prenatal diagnostic testing for retinoblastoma compared to other hereditary cancer syndromes in the Netherlands
inferred← citeshttps://doi.org/10.1007/s10689-016-9964-7openalex-snapshot
Psychosocial morbidity in TP53 mutation carriers: is whole-body cancer screening beneficial?
inferred← citeshttps://doi.org/10.1007/s10689-017-0028-4openalex-snapshot
p53 signaling pathway polymorphisms, cancer risk and tumor phenotype in TP53 R337H mutation carriers
inferred← citeshttps://doi.org/10.1007/s10689-019-00153-5openalex-snapshot
Radiotherapy-induced malignancies in breast cancer patients with TP53 pathogenic germline variants (Li–Fraumeni syndrome)
inferred← citeshttps://doi.org/10.1007/s10863-025-10059-wopenalex-snapshot
The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer
inferred← citeshttps://doi.org/10.1007/s10897-015-9905-xopenalex-snapshot
Easing the Burden: Describing the Role of Social, Emotional and Spiritual Support in Research Families with Li‐Fraumeni Syndrome
inferred← citeshttps://doi.org/10.1007/s10897-018-0288-7openalex-snapshot
Lay Perspectives on Receiving Different Types of Genomic Secondary Findings: a Qualitative Vignette Study
inferred← citeshttps://doi.org/10.1007/s11010-017-2977-1openalex-snapshot
Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors
inferred← citeshttps://doi.org/10.1007/s11033-022-07840-0openalex-snapshot
Frequency of germline genetic variants in women with a personal or family history of breast cancer from Brazil
inferred← citeshttps://doi.org/10.1007/s11060-020-03509-5openalex-snapshot
Epigenetics impacts upon prognosis and clinical management of choroid plexus tumors
inferred← citeshttps://doi.org/10.1007/s11670-012-0232-6openalex-snapshot
Inhibitory effects of 5-Aza-2′-deoxycytidine and trichostatin A in combination with p53-expressing adenovirus on human laryngocarcinoma cells
inferred← citeshttps://doi.org/10.1007/s11899-022-00663-7openalex-snapshot
Germline CHEK2 and ATM Variants in Myeloid and Other Hematopoietic Malignancies
inferred← citeshttps://doi.org/10.1007/s12609-018-0282-yopenalex-snapshot
Risk and Prevention for Highly Penetrant Genes
inferred← citeshttps://doi.org/10.1007/s12609-023-00478-2openalex-snapshot
Genetic Considerations in the Locoregional Management of Breast Cancer: a Review of Current Evidence
inferred← citeshttps://doi.org/10.1007/s13577-025-01198-8openalex-snapshot
Establishment and characterization of NCC-OS2-C1: a novel patient-derived cell line of osteosarcoma
inferred← citeshttps://doi.org/10.1007/s40291-013-0020-0openalex-snapshot
Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome
inferred← citeshttps://doi.org/10.1007/s40487-017-0047-1openalex-snapshot
DNA Mutations May Not Be the Cause of Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-800249-0.00008-1openalex-snapshot
Genetically Engineered Mice as Experimental Tools to Dissect the Critical Events in Breast Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-801565-0.00004-4openalex-snapshot
Etio-pathogenesis I
inferred← citeshttps://doi.org/10.1016/b978-0-12-801565-0.00007-xopenalex-snapshot
Etio-Pathogenesis IV
inferred← citeshttps://doi.org/10.1016/b978-0-12-811785-9.00043-0openalex-snapshot
Advances in Sarcoma Genomics and Therapeutic Management
inferred← citeshttps://doi.org/10.1016/b978-0-12-816920-9.00005-5openalex-snapshot
Hereditary predispositions to tumors, tumor suppressor genes, and their clinico-genomic complexities
inferred← citeshttps://doi.org/10.1016/b978-0-12-821567-8.00013-0openalex-snapshot
p53 supplementation as a targeted cancer gene therapy for glioblastoma
inferred← citeshttps://doi.org/10.1016/b978-0-323-48555-5.00007-7openalex-snapshot
Cancer Syndromes That Present in Childhood
inferred← citeshttps://doi.org/10.1016/b978-0-323-52480-3.50100-1openalex-snapshot
Adrenal Cortical Neoplasms in Children
inferred← citeshttps://doi.org/10.1016/bs.acr.2025.08.008openalex-snapshot
An overview of the diagnosis and management of Choroid Plexus tumors
inferred← citeshttps://doi.org/10.1016/j.advms.2016.12.002openalex-snapshot
A novel germline TP53 mutation p.Pro190Arg detected in a patient with lung and bilateral breast cancers
inferred← citeshttps://doi.org/10.1016/j.ajhg.2023.08.014openalex-snapshot
Current and new frontiers in hereditary cancer surveillance: Opportunities for liquid biopsy
inferred← citeshttps://doi.org/10.1016/j.ajhg.2026.07.011openalex-snapshot
Shared inheritance reveals landscape of somatic and germline cancer risk in TP53
inferred← citeshttps://doi.org/10.1016/j.ajoms.2019.05.004openalex-snapshot
A rare mandibular osteosarcoma case of Li-Franmeni syndrome with a germline p53R273H mutation
inferred← citeshttps://doi.org/10.1016/j.annpat.2020.02.015openalex-snapshot
Les tumeurs héréditaires de l’ovaire vues par le pathologiste
inferred← citeshttps://doi.org/10.1016/j.bbadis.2024.167612openalex-snapshot
tp53 R217H and R242H mutant zebrafish exhibit dysfunctional p53 hallmarks and recapitulate Li-Fraumeni syndrome phenotypes
inferred← citeshttps://doi.org/10.1016/j.bbcan.2020.188339openalex-snapshot
BRCA1/P53: Two strengths in cancer chemoprevention
inferred← citeshttps://doi.org/10.1016/j.bbcan.2021.188556openalex-snapshot
Tumor suppressor p53: Biology, signaling pathways, and therapeutic targeting
inferred← citeshttps://doi.org/10.1016/j.bbcan.2022.188843openalex-snapshot
Amazing roles of extrachromosomal DNA in cancer progression
inferred← citeshttps://doi.org/10.1016/j.beem.2026.102099openalex-snapshot
Germline and somatic genetic drivers of adrenocortical tumours
inferred← citeshttps://doi.org/10.1016/j.biocel.2018.12.008openalex-snapshot
Induced pluripotent stem cells: A new strategy to model human cancer
inferred← citeshttps://doi.org/10.1016/j.biochi.2023.09.026openalex-snapshot
Transactivation by partial function P53 family mutants is increased by the presence of G-quadruplexes at a promoter site
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115256openalex-snapshot
Current progress of pig models for liver cancer research
inferred← citeshttps://doi.org/10.1016/j.breast.2023.02.002openalex-snapshot
A matched case-control study of the prognosis of early breast cancer in patients with Li-Fraumeni syndrome (BREAST TP53)
inferred← citeshttps://doi.org/10.1016/j.cancergen.2015.03.004openalex-snapshot
Genomic profile of a Li-Fraumeni-like syndrome patient with a 45,X/46,XX karyotype, presenting neither mutations in TP53 nor clinical stigmata of Turner syndrome
inferred← citeshttps://doi.org/10.1016/j.cancergen.2015.12.012openalex-snapshot
Rare germline variant (rs78378222) in the TP53 3' UTR: Evidence for a new mechanism of cancer predisposition in Li-Fraumeni syndrome
inferred← citeshttps://doi.org/10.1016/j.cancergen.2019.11.005openalex-snapshot
MIR605 rs2043556 is associated with the occurrence of multiple primary tumors in TP53 p.(Arg337His) mutation carriers
inferred← citeshttps://doi.org/10.1016/j.cancergen.2021.10.002openalex-snapshot
Molecular profiling of osteosarcoma in children and adolescents from different age groups using a next-generation sequencing panel
inferred← citeshttps://doi.org/10.1016/j.canep.2021.101947openalex-snapshot
Individual and neighbourhood socioeconomic measures and the risk of non-central nervous system solid tumours in children: A nationwide register-based case-control study in Denmark
inferred← citeshttps://doi.org/10.1016/j.cell.2026.03.005openalex-snapshot
Senescence in cancer: Hallmarks, paradoxes, and therapeutic promise
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.06.057openalex-snapshot
Systemic Akt1 Deletion after Tumor Onset in p53 Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.11.007openalex-snapshot
p53 Regulates Progenitor Cell Quiescence and Differentiation in the Airway
inferred← citeshttps://doi.org/10.1016/j.clinthera.2016.03.017openalex-snapshot
Advances in Hereditary Colorectal and Pancreatic Cancers
inferred← citeshttps://doi.org/10.1016/j.clinthera.2016.03.037openalex-snapshot
Cancer Genomics: Targeting Inherited Risk and Somatic Mutations in Precision Oncology
inferred← citeshttps://doi.org/10.1016/j.cllc.2019.11.012openalex-snapshot
High Prevalence of EGFR Mutations in Lung Adenocarcinomas From Brazilian Patients Harboring the TP53 p.R337H Variant
inferred← citeshttps://doi.org/10.1016/j.coisb.2016.12.015openalex-snapshot
Prevalence and penetrance of Li-Fraumeni cancer predisposition syndrome
inferred← citeshttps://doi.org/10.1016/j.ctro.2017.10.004openalex-snapshot
Increasing genomic instability during cancer therapy in a patient with Li-Fraumeni syndrome
inferred← citeshttps://doi.org/10.1016/j.ctrv.2017.11.001openalex-snapshot
Advances in sarcoma gene mutations and therapeutic targets
inferred← citeshttps://doi.org/10.1016/j.dnarep.2019.05.004openalex-snapshot
Crosstalk between P53 and DNA damage response in ageing
inferred← citeshttps://doi.org/10.1016/j.ejca.2019.05.005openalex-snapshot
Reproductive factors associated with breast cancer risk in Li–Fraumeni syndrome
inferred← citeshttps://doi.org/10.1016/j.gene.2023.148069openalex-snapshot
Functional pri-miR-34b/c rs4938723 and KRAS 3′UTR rs61764370 SNPs: Novel phenotype modifiers in Li-Fraumeni Syndrome?
inferred← citeshttps://doi.org/10.1016/j.giec.2021.03.010openalex-snapshot
Inherited Predisposition to Gastric Cancer
inferred← citeshttps://doi.org/10.1016/j.humpath.2017.06.018openalex-snapshot
Pathologic findings in breast, fallopian tube, and ovary specimens in non- BRCA hereditary breast and/or ovarian cancer syndromes: a study of 18 patients with deleterious germline mutations in RAD51C , BARD1 , BRIP1 , PALB2 , MUTYH , or CHEK2
inferred← citeshttps://doi.org/10.1016/j.humpath.2018.06.024openalex-snapshot
Clinicopathologic characterization of breast carcinomas in patients with non-BRCA germline mutations: results from a single institution’s high-risk population
inferred← citeshttps://doi.org/10.1016/j.ijrobp.2018.01.096openalex-snapshot
Does Prophylactic Radiation Therapy to Avoid Gynecomastia in Patients With Prostate Cancer Increase the Risk of Breast Cancer?
inferred← citeshttps://doi.org/10.1016/j.ijscr.2024.110323openalex-snapshot
Her2-positive breast cancer in a young patient with Li-Fraumeni syndrome: A comprehensive case study
inferred← citeshttps://doi.org/10.1016/j.jgg.2021.12.012openalex-snapshot
Characteristics of TP53 germline variants and their correlations with Li-Fraumeni syndrome or Li-Fraumeni-like syndrome in Chinese tumor patients
inferred← citeshttps://doi.org/10.1016/j.jid.2022.02.004openalex-snapshot
Spectrum and Incidence of Skin Cancer among Individuals with Li-Fraumeni Syndrome
inferred← citeshttps://doi.org/10.1016/j.jmb.2022.167663openalex-snapshot
Cancer-related Mutations with Local or Long-range Effects on an Allosteric Loop of p53
inferred← citeshttps://doi.org/10.1016/j.jpedsurg.2016.01.004openalex-snapshot
Risk-reduction surgery in pediatric surgical oncology: A perspective
inferred← citeshttps://doi.org/10.1016/j.lana.2022.100265openalex-snapshot
Cancer surveillance for patients with Li-Fraumeni Syndrome in Brazil: A cost-effectiveness analysis
inferred← citeshttps://doi.org/10.1016/j.lrr.2025.100538openalex-snapshot
Le lymphome cutanée primitif diffus à grandes cellules B : à propos d’un cas Primary cutaneous diffuse large B-cell lymphoma: a case report
inferred← citeshttps://doi.org/10.1016/j.lungcan.2014.11.005openalex-snapshot
EFGR-mutant lung adenocarcinoma and Li-Fraumeni syndrome: Report of two cases and review of the literature
inferred← citeshttps://doi.org/10.1016/j.mpdhp.2012.01.003openalex-snapshot
Li–Fraumeni syndrome: a role for surgical pathologists?
inferred← citeshttps://doi.org/10.1016/j.pan.2022.05.005openalex-snapshot
Identification of high-risk germline variants for the development of pancreatic cancer: Common characteristics and potential guidance to screening guidelines
inferred← citeshttps://doi.org/10.1016/j.pcl.2014.09.013openalex-snapshot
Genetic and Nongenetic Risk Factors for Childhood Cancer
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.105245openalex-snapshot
p73: From the p53 shadow to a major pharmacological target in anticancer therapy
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2017.05.019openalex-snapshot
CRISPR-engineered genome editing for the next generation neurological disease modeling
inferred← citeshttps://doi.org/10.1016/j.rmcr.2018.03.006openalex-snapshot
Multiple metachronous and synchronous malignancies with lung and thorax involvement. Report of two cases
inferred← citeshttps://doi.org/10.1016/j.semcancer.2019.08.021openalex-snapshot
Statistical genomics in rare cancer
inferred← citeshttps://doi.org/10.1016/j.semcancer.2022.02.002openalex-snapshot
Targeting OXPHOS and the electron transport chain in cancer; Molecular and therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.semcdb.2013.12.014openalex-snapshot
Illuminating p53 function in cancer with genetically engineered mouse models
inferred← citeshttps://doi.org/10.1016/j.soc.2015.06.006openalex-snapshot
The Genetics of Colorectal Cancer
inferred← citeshttps://doi.org/10.1016/j.tranon.2020.100922openalex-snapshot
Bacterial nucleomodulins and cancer: An unresolved enigma
inferred← citeshttps://doi.org/10.1016/j.trecan.2019.11.004openalex-snapshot
Mutant p53 on the Path to Metastasis
inferred← citeshttps://doi.org/10.1016/j.wneu.2018.08.203openalex-snapshot
Pediatric Case of Li-Fraumeni Syndrome Complicated with Supratentorial Anaplastic Ependymoma
inferred← citeshttps://doi.org/10.1016/j.yasu.2014.05.004openalex-snapshot
Screening for Pancreatic Cancer
inferred← citeshttps://doi.org/10.1016/j.yexcr.2014.09.028openalex-snapshot
Studying p53 family proteins in yeast: Induction of autophagic cell death and modulation by interactors and small molecules
inferred← citeshttps://doi.org/10.1016/j.ygyno.2007.03.040openalex-snapshot
Myeloid sarcoma of the vulva as the presenting symptom in a patient with acute myeloid leukemia
inferred← citeshttps://doi.org/10.1016/s0025-7753(07)72466-1openalex-snapshot
Nuevos retos de la oncología molecular en el cáncer de ovario
inferred← citeshttps://doi.org/10.1016/s0246-0467(22)43449-0openalex-snapshot
10.1016/s0246-0467(22)43449-0
inferred← citeshttps://doi.org/10.1016/s1097-2765(02)00527-0openalex-snapshot
Structural and Functional Versatility of the FHA Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
inferred← citeshttps://doi.org/10.1016/s2211-033x(22)47101-5openalex-snapshot
Principios del tratamiento quirúrgico de los sarcomas de tejidos blandos
inferred← citeshttps://doi.org/10.1016/s2211-0801(23)00005-5openalex-snapshot
Principi di trattamento chirurgico dei sarcomi dei tessuti molli
inferred← citeshttps://doi.org/10.1021/tx500403topenalex-snapshot
Pyrrolizidine Alkaloids: Potential Role in the Etiology of Cancers, Pulmonary Hypertension, Congenital Anomalies, and Liver Disease
inferred← citeshttps://doi.org/10.1038/ejhg.2013.68openalex-snapshot
Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours
inferred← citeshttps://doi.org/10.1038/nature22312openalex-snapshot
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations
inferred← citeshttps://doi.org/10.1038/ng.2532openalex-snapshot
The genomic landscape of hypodiploid acute lymphoblastic leukemia
inferred← citeshttps://doi.org/10.1038/npjgenmed.2016.15openalex-snapshot
Germline hemizygous deletion of CDKN2A–CDKN2B locus in a patient presenting with Li–Fraumeni syndrome
inferred← citeshttps://doi.org/10.1038/nrclinonc.2014.41openalex-snapshot
Li-Fraumeni syndrome: cancer risk assessment and clinical management
inferred← citeshttps://doi.org/10.1038/nrendo.2017.16openalex-snapshot
Germline and somatic genetics of osteosarcoma — connecting aetiology, biology and therapy
inferred← citeshttps://doi.org/10.1038/s41388-020-1361-xopenalex-snapshot
NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity
inferred← citeshttps://doi.org/10.1038/s41392-025-02549-5openalex-snapshot
p53: from understanding its structure to advances in therapeutic targeting
inferred← citeshttps://doi.org/10.1038/s41409-026-02838-9openalex-snapshot
Impact of TP53 alterations on outcomes in pediatric and young adult patients with relapsed / refractory B-cell acute lymphoblastic leukemia after CD19-CAR T-Cell therapy
inferred← citeshttps://doi.org/10.1038/s41416-023-02204-2openalex-snapshot
Is it still worth pursuing the repurposing of metformin as a cancer therapeutic?
inferred← citeshttps://doi.org/10.1038/s41418-022-00962-9openalex-snapshot
Should mutant TP53 be targeted for cancer therapy?
inferred← citeshttps://doi.org/10.1038/s41418-023-01236-8openalex-snapshot
Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent
inferred← citeshttps://doi.org/10.1038/s41419-021-03638-3openalex-snapshot
Single loss of a Trp53 allele triggers an increased oxidative, DNA damage and cytokine inflammatory responses through deregulation of IκBα expression
inferred← citeshttps://doi.org/10.1038/s41420-017-0009-2openalex-snapshot
Modeling cancer using patient-derived induced pluripotent stem cells to understand development of childhood malignancies
inferred← citeshttps://doi.org/10.1038/s41431-026-02014-zopenalex-snapshot
Non-invasive screening in hereditary cancer: a randomized controlled trial to test cell-free DNA-based early detection in the CHARM consortium
inferred← citeshttps://doi.org/10.1038/s41431-026-02061-6openalex-snapshot
Tumor patterns and cancer risk in carriers of TP53 exonic germline variants that alter mRNA splicing
inferred← citeshttps://doi.org/10.1038/s41467-020-17596-5openalex-snapshot
Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome
inferred← citeshttps://doi.org/10.1038/s41467-024-51529-wopenalex-snapshot
Cell-free DNA from germline TP53 mutation carriers reflect cancer-like fragmentation patterns
inferred← citeshttps://doi.org/10.1038/s41467-025-62894-5openalex-snapshot
Peripheral blood DNA methylation predicts the early onset of primary tumor in TP53 mutation carriers
inferred← citeshttps://doi.org/10.1038/s41467-026-73163-4openalex-snapshot
Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers
inferred← citeshttps://doi.org/10.1038/s41525-018-0074-3openalex-snapshot
Rare TP53 variant associated with Li-Fraumeni syndrome exhibits variable penetrance in a Saudi family
inferred← citeshttps://doi.org/10.1038/s41556-017-0009-8openalex-snapshot
Mechanical cues control mutant p53 stability through a mevalonate–RhoA axis
inferred← citeshttps://doi.org/10.1038/s41568-020-0265-yopenalex-snapshot
Tumour predisposition and cancer syndromes as models to study gene–environment interactions
inferred← citeshttps://doi.org/10.1038/s41598-017-10333-xopenalex-snapshot
Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas
inferred← citeshttps://doi.org/10.1038/s41598-019-51735-3openalex-snapshot
Radiation-induced malignancies after intensity-modulated versus conventional mediastinal radiotherapy in a small animal model
inferred← citeshttps://doi.org/10.1038/s44320-024-00032-xopenalex-snapshot
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
inferred← citeshttps://doi.org/10.1039/c8ra08246dopenalex-snapshot
Design, synthesis, and bioactivity evaluation of antitumor sorafenib analogues
inferred← citeshttps://doi.org/10.1053/j.gastro.2005.10.014openalex-snapshot
Prevalence of Early Onset Colorectal Cancer in 397 Patients With Classic Li–Fraumeni Syndrome
inferred← citeshttps://doi.org/10.1053/j.gastro.2018.10.063openalex-snapshot
Early-Onset Colorectal Cancer in Patients with Li Fraumeni Syndrome: Is It Really Enough to Justify Early Colon Cancer Screening?
inferred← citeshttps://doi.org/10.1053/j.seminoncol.2015.09.015openalex-snapshot
Hereditary cancer syndromes as model systems for chemopreventive agent development
inferred← citeshttps://doi.org/10.1053/j.seminoncol.2016.10.001openalex-snapshot
Updates on breast cancer genetics: Clinical implications of detecting syndromes of inherited increased susceptibility to breast cancer
inferred← citeshttps://doi.org/10.1053/j.sempedsurg.2005.11.008openalex-snapshot
Malignant adrenal tumors
inferred← citeshttps://doi.org/10.1055/s-0042-1757325openalex-snapshot
The Molecular Genetics of Colorectal Cancer, Hereditary Colorectal Cancer Syndromes, and Early-Onset Colorectal Cancer
inferred← citeshttps://doi.org/10.1056/nejm200012213432508openalex-snapshot
Hyperparathyroid and Hypoparathyroid Disorders
inferred← citeshttps://doi.org/10.1080/14737159.2022.2049247openalex-snapshot
Reviewing the occurrence of large genomic rearrangements in patients with inherited cancer predisposing syndromes: importance of a comprehensive molecular diagnosis
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