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Similarities between COVID-19 and anti-MDA5 syndrome: what can we learn for better care?

https://doi.org/10.1183/13993003.01618-2020
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/art.41105openalex-snapshot
Multicenter Prospective Study of the Efficacy and Safety of Combined Immunosuppressive Therapy With High‐Dose Glucocorticoid, Tacrolimus, and Cyclophosphamide in Interstitial Lung Diseases Accompanied by Anti–Melanoma Differentiation–Associated Gene 5–Positive Dermatomyositis
inferredcites →https://doi.org/10.1016/j.jaci.2020.05.019openalex-snapshot
Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial
inferredcites →https://doi.org/10.1016/j.rmed.2011.05.006openalex-snapshot
HRCT features of interstitial lung disease in dermatomyositis with anti-CADM-140 antibody
inferredcites →https://doi.org/10.1016/j.tim.2018.08.007openalex-snapshot
A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation
inferredcites →https://doi.org/10.1016/j.virusres.2012.02.002openalex-snapshot
Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506
inferredcites →https://doi.org/10.1016/s0140-6736(20)30628-0openalex-snapshot
COVID-19: consider cytokine storm syndromes and immunosuppression
inferredcites →https://doi.org/10.1038/d41586-020-01824-5openalex-snapshot
Coronavirus breakthrough: dexamethasone is first drug shown to save lives
inferredcites →https://doi.org/10.1056/nejmc1900045openalex-snapshot
Tofacitinib in Amyopathic Dermatomyositis–Associated Interstitial Lung Disease
inferredcites →https://doi.org/10.1080/14397595.2018.1548918openalex-snapshot
Serum neopterin as well as ferritin, soluble interleukin-2 receptor, KL-6 and anti-MDA5 antibody titer provide markers of the response to therapy in patients with interstitial lung disease complicating anti-MDA5 antibody-positive dermatomyositis
inferredcites →https://doi.org/10.1093/rheumatology/keu258openalex-snapshot
Cytokine profiles in polymyositis and dermatomyositis complicated by rapidly progressive or chronic interstitial lung disease
inferredcites →https://doi.org/10.1093/rheumatology/key188openalex-snapshot
Tofacitinib for refractory interstitial lung diseases in anti-melanoma differentiation-associated 5 gene antibody-positive dermatomyositis
inferredcites →https://doi.org/10.1111/1346-8138.14092openalex-snapshot
Associations between anti‐melanoma differentiation‐associated gene 5 antibody and demographics, clinical characteristics and laboratory results of patients with dermatomyositis: A systematic meta‐analysis
inferredcites →https://doi.org/10.1212/wnl.0000000000009727openalex-snapshot
Different phenotypes in dermatomyositis associated with anti-MDA5 antibody

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Diagnostic Challenge of Anti-MDA5 Myositis with Respiratory Failure During COVID-19 Pandemic
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Presence and Implications of Anti‐Angiotensin Converting Enzyme‐2 Immunoglobulin M Antibodies in Anti‐Melanoma‐Differentiation‐Associated 5 Dermatomyositis
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Prognostic Role of Interferon‐λ3 in Anti–Melanoma Differentiation–Associated Gene 5–Positive Dermatomyositis‐Associated Interstitial Lung Disease
inferred← citeshttps://doi.org/10.1002/ctm2.70226openalex-snapshot
Monocyte–macrophage dynamics as key in disparate lung and peripheral immune responses in severe anti‐melanoma differentiation‐associated gene 5‐positive dermatomyositis‐related interstitial lung disease
inferred← citeshttps://doi.org/10.1007/978-981-19-1946-6_23openalex-snapshot
Microorganisms in Pathogenesis and Management of Dermatomyositis (DM) and Polymyositis (PM)
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Understanding and managing anti-MDA 5 dermatomyositis, including potential COVID-19 mimicry
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Anti-MDA5 dermatomyositis after COVID-19 vaccination: a case-based review
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COVID-19 and Myositis: What We Know So Far
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The Role of Environmental Factors in the Development of Idiopathic Inflammatory Myopathies: a Narrative Review
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MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients
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Advances in Biomarkers and Therapeutic Targets for Idiopathic Inflammatory Myopathies Related Lung Disease
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Pharmacologic Treatment of Anti-MDA5 Rapidly Progressive Interstitial Lung Disease
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Expanding the spectrum of the hyperferritinemic syndrome, from pathogenic mechanisms to clinical observations, and therapeutic implications
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COVID-19 and the antiphospholipid syndrome
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Environmental Risks for Inflammatory Myopathies
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COVID-19 and interstitial lung diseases: A multifaceted look at the relationship between the two diseases
inferred← citeshttps://doi.org/10.1016/s2665-9913(20)30270-8openalex-snapshot
B-cell depletion with rituximab in the COVID-19 pandemic: where do we stand?
inferred← citeshttps://doi.org/10.1038/s41409-022-01730-6openalex-snapshot
Interstitial lung disease with anti-melanoma differentiation-associated gene 5 antibody after allogeneic hematopoietic stem cell transplantation
inferred← citeshttps://doi.org/10.1038/s41467-022-34145-4openalex-snapshot
Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications
inferred← citeshttps://doi.org/10.1038/s41584-023-01054-9openalex-snapshot
Anti-MDA5 antibody-positive dermatomyositis: pathogenesis and clinical progress
inferred← citeshttps://doi.org/10.1038/s41598-025-10895-1openalex-snapshot
Dysregulated type I/III interferon system in circulation from patients with anti-MDA5-positive dermatomyositis
inferred← citeshttps://doi.org/10.1093/omcr/omab061openalex-snapshot
Clinically amyopathic dermatomyositis during the COVID-19 pandemic
inferred← citeshttps://doi.org/10.1093/rheumatology/keaa816openalex-snapshot
The aetiopathogenic significance, clinical relevance and therapeutic implications of vasculopathy in idiopathic inflammatory myopathy
inferred← citeshttps://doi.org/10.1093/rheumatology/keab371openalex-snapshot
Antiviral proinflammatory phenotype of monocytes in anti-MDA5 antibody-associated interstitial lung disease
inferred← citeshttps://doi.org/10.1093/rheumatology/keac450openalex-snapshot
Time-dependent changes in RPILD and mortality risk in anti-MDA5+ DM patients: a cohort study of 272 cases in China
inferred← citeshttps://doi.org/10.1097/bor.0000000000000908openalex-snapshot
Anti-MDA5 dermatomyositis: an update from bench to bedside
inferred← citeshttps://doi.org/10.1101/2020.07.29.20164780openalex-snapshot
Analysis of the correlation between anti-MDA5 antibody and the severity of COVID-19: a retrospective study
inferred← citeshttps://doi.org/10.1111/1744-9987.14106openalex-snapshot
Effectiveness and safety of plasma exchange for anti‐MDA5 antibody–positive clinically amyopathic dermatomyositis with rapidly progressive interstitial lung disease refractory to intensive immune suppression therapy: A case series
inferred← citeshttps://doi.org/10.1172/jci154886openalex-snapshot
The intersection of COVID-19 and autoimmunity
inferred← citeshttps://doi.org/10.1186/s12575-021-00145-9openalex-snapshot
Effects of Cell Proteostasis Network on the Survival of SARS-CoV-2
inferred← citeshttps://doi.org/10.1186/s12890-026-04272-5openalex-snapshot
Dual-positive anti-aminoacyl-tRNA synthetase and anti-melanoma differentiation-associated gene 5 antibody-related rapidly progressive interstitial lung disease in a patient with severe coronavirus disease 2019 complicated by probable pulmonary aspergillosis and pneumothorax: a case report
inferred← citeshttps://doi.org/10.1186/s13075-025-03639-zopenalex-snapshot
Single-cell sequencing reveals distinct peripheral immune responses in anti-MDA5 antibody positive dermatomyositis with rapidly progressive interstitial lung disease
inferred← citeshttps://doi.org/10.1186/s43042-024-00601-7openalex-snapshot
The IFIH1 gene variants rs1990760 and rs2111485 are associated with COVID-19 susceptibility and affect IFIH1 protein levels in Iraqis
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Inflammatory Myopathies
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Anti-MDA5 Antibody Positive Clinically Amyopathic Dermatomyositis Associated with Rapidly Progressive Interstitial Lung Disease
inferred← citeshttps://doi.org/10.12998/wjcc.v11.i23.5580openalex-snapshot
Anti-melanoma differentiation-associated gene 5 and anti-Ro52 antibody-dual positive dermatomyositis accompanied by rapidly lung disease: Three case reports
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Rapidly Progressive Interstitial Lung Disease Associated with Melanoma Differentiation-Associated Gene 5 Antibody
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А new coronavirus infection associated CNS involvement in children: literature review and clinical case description
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The possible role of molecular mimicry in SARS-CoV-2-mediated autoimmunity: an immunobiochemical basis
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Comparison of chest radiological findings between coronavirus disease 2019 pneumonia and anti-melanoma differentiation-associated gene 5 antibody- positive interstitial pneumonia by artificial intelligence-based quantitative computed tomography image analysis
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New-onset Anti-melanoma Differentiation-associated Gene 5 Antibody Positive Clinically Amyopathic Dermatomyositis Following COVID-19
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COVID-19: A Great Mime or a Trigger Event of Autoimmune Manifestations?
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A novel intergenic variant linked to IFIH1 rs1990760 polymorphism, rs2111485, shows an association with susceptibility to coronavirus disease 2019 and influences IFIH1 protein levels.
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Dermatomyositis With Anti-MDA5 Antibodies: Bioclinical Features, Pathogenesis and Emerging Therapies
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Presence of Anti-MDA5 Antibody and Its Value for the Clinical Assessment in Patients With COVID-19: A Retrospective Cohort Study
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Rituximab in the Treatment of Interstitial Lung Diseases Related to Anti-Melanoma Differentiation-Associated Gene 5 Dermatomyositis: A Systematic Review
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New-onset dermatomyositis following COVID-19: A case report
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Transcriptomic profiling and longitudinal study reveal the relationship of anti-MDA5 titer and type I IFN signature in MDA5+ dermatomyositis
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Editorial: Advances in understanding the pathogenesis of and designing therapies for connective tissue disease-associated interstitial lung disease
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Unraveling Muscle Impairment Associated With COVID-19 and the Role of 3D Culture in Its Investigation
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Baricitinib and Pulse Steroids Combination Treatment in Hyperinflammatory COVID-19: A Rheumatological Approach in the Intensive Care Unit
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Two-Years Follow-Up of Symptoms and Return to Work in Complex Post-COVID-19 Patients
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Interstitial Lung Disease (ILD) in Immune Inflammatory Myopathies—A Comprehensive Review Focusing on ILD in Antisynthetase Syndrome and MDA5 Dermatomyositis
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Vitamin D Serum Levels and the Development of Intensive Care Unit-Acquired Weakness: Insights from a COVID-19 Intensive Care Cohort
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Persistent SARS-CoV-2 Infection, EBV, HHV-6 and Other Factors May Contribute to Inflammation and Autoimmunity in Long COVID
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Antimelanoma Differentiation-Associated Gene 5 Antibody–Positive Interstitial Lung Disease After Vaccination With COVID-19 mRNA Vaccines
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Dr. Kitajima et al reply
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Efficacy of plasma exchange for rapidly progressive interstitial lung disease caused by anti-MDA5 antibody-positive dermatomyositis: Report of a case showing resistance to combined immunosuppressive treatment
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