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Metabolic pathway engineering based on metabolomics confers acetic and formic acid tolerance to a recombinant xylose-fermenting strain of Saccharomyces cerevisiae

https://doi.org/10.1186/1475-2859-10-2
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jctb.1676openalex-snapshot
Increased tolerance and conversion of inhibitors in lignocellulosic hydrolysates by Saccharomyces cerevisiae
inferredcites →https://doi.org/10.1002/yea.1370openalex-snapshot
A 5‐hydroxymethyl furfural reducing enzyme encoded by the Saccharomyces cerevisiae ADH6 gene conveys HMF tolerance
inferredcites →https://doi.org/10.1002/yea.1578openalex-snapshot
Identification of an NADH‐dependent 5‐hydroxymethylfurfural‐reducing alcohol dehydrogenase in Saccharomyces cerevisiae
inferredcites →https://doi.org/10.1002/yea.320010108openalex-snapshot
Primary structure of the Saccharomyces cerevisiae GAL7 gene
inferredcites →https://doi.org/10.1007/10_2007_057openalex-snapshot
Development of Efficient Xylose Fermentation in Saccharomyces cerevisiae: Xylose Isomerase as a Key Component
inferredcites →https://doi.org/10.1007/bf00902736openalex-snapshot
Isolation and characterization of the Pichia stipitis transketolase gene and expression in a xylose-utilising Saccharomyces cerevisiae transformant
inferredcites →https://doi.org/10.1007/bf02921515openalex-snapshot
Isolation of acetic acid-tolerant Baker’s yeast variants in a turbidostat
inferredcites →https://doi.org/10.1007/s00253-004-1798-9openalex-snapshot
Xylose chemostat isolates of Saccharomyces cerevisiae show altered metabolite and enzyme levels compared with xylose, glucose, and ethanol metabolism of the original strain
inferredcites →https://doi.org/10.1007/s00253-005-0142-3openalex-snapshot
Tolerance to furfural-induced stress is associated with pentose phosphate pathway genes ZWF1, GND1, RPE1, and TKL1 in Saccharomyces cerevisiae
inferredcites →https://doi.org/10.1007/s00253-006-0575-3openalex-snapshot
High activity of xylose reductase and xylitol dehydrogenase improves xylose fermentation by recombinant Saccharomyces cerevisiae
inferredcites →https://doi.org/10.1007/s00253-007-1029-2openalex-snapshot
Metabolomics: current state and evolving methodologies and tools
inferredcites →https://doi.org/10.1007/s00253-009-2101-xopenalex-snapshot
Ethanol production from xylose in engineered Saccharomyces cerevisiae strains: current state and perspectives
inferredcites →https://doi.org/10.1007/s00253-009-2198-yopenalex-snapshot
Novel strategy for yeast construction using δ-integration and cell fusion to efficiently produce ethanol from raw starch
inferredcites →https://doi.org/10.1007/s002530100742openalex-snapshot
Effect of overexpression of Saccharomyces cerevisiae Pad1p on the resistance to phenylacrylic acids and lignocellulose hydrolysates under aerobic and oxygen-limited conditions
inferredcites →https://doi.org/10.1007/s00438-009-0461-7openalex-snapshot
Evolutionarily engineered ethanologenic yeast detoxifies lignocellulosic biomass conversion inhibitors by reprogrammed pathways
inferredcites →https://doi.org/10.1007/s10482-006-9085-7openalex-snapshot
Alcoholic fermentation of carbon sources in biomass hydrolysates by Saccharomyces cerevisiae: current status
inferredcites →https://doi.org/10.1007/s11306-008-0116-4openalex-snapshot
Leakage-free rapid quenching technique for yeast metabolomics
inferredcites →https://doi.org/10.1007/s12010-007-9063-1openalex-snapshot
Dilute sulfuric acid pretreatment of agricultural and agro-industrial residues for ethanol production
inferredcites →https://doi.org/10.1016/0003-2697(90)90595-zopenalex-snapshot
Molecular cloning: A laboratory manual
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Fermentative performance of bacteria and yeasts in lignocellulose hydrolysates
inferredcites →https://doi.org/10.1016/j.biortech.2003.08.011openalex-snapshot
Xylose fermentation by genetically modified Saccharomyces cerevisiae 259ST in spent sulfite liquor
inferredcites →https://doi.org/10.1016/j.biotechadv.2007.04.001openalex-snapshot
Genetic improvement of Saccharomyces cerevisiae for xylose fermentation
inferredcites →https://doi.org/10.1016/j.copbio.2006.05.008openalex-snapshot
Engineering yeasts for xylose metabolism
inferredcites →https://doi.org/10.1016/j.enzmictec.2008.03.001openalex-snapshot
Improvement of ethanol productivity during xylose and glucose co-fermentation by xylose-assimilating S. cerevisiae via expression of glucose transporter Sut1
inferredcites →https://doi.org/10.1016/j.jbiotec.2009.05.001openalex-snapshot
Mechanisms of yeast stress tolerance and its manipulation for efficient fuel ethanol production
inferredcites →https://doi.org/10.1016/j.mib.2008.04.002openalex-snapshot
Separation and mass spectrometry in microbial metabolomics
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Mass spectrometry based metabolomics and enzymatic assays for functional genomics
inferredcites →https://doi.org/10.1016/j.tibtech.2006.10.004openalex-snapshot
Bio-ethanol – the fuel of tomorrow from the residues of today
inferredcites →https://doi.org/10.1016/s0141-0229(03)00214-xopenalex-snapshot
Effect of inhibitory compounds found in biomass hydrolysates on growth and xylose fermentation by a genetically engineered strain of S. cerevisiae
inferredcites →https://doi.org/10.1016/s0141-0229(98)00101-xopenalex-snapshot
The generation of fermentation inhibitors during dilute acid hydrolysis of softwood
inferredcites →https://doi.org/10.1016/s0960-8524(99)00161-3openalex-snapshot
Fermentation of lignocellulosic hydrolysates. II: inhibitors and mechanisms of inhibition
inferredcites →https://doi.org/10.1021/ac0202684openalex-snapshot
Pressure-Assisted Capillary Electrophoresis Electrospray Ionization Mass Spectrometry for Analysis of Multivalent Anions
inferredcites →https://doi.org/10.1021/ac900999topenalex-snapshot
Quantitative Evaluation of Intracellular Metabolite Extraction Techniques for Yeast Metabolomics
inferredcites →https://doi.org/10.1021/jf062330uopenalex-snapshot
Prediction of Japanese Green Tea Ranking by Gas Chromatography/Mass Spectrometry-Based Hydrophilic Metabolite Fingerprinting
inferredcites →https://doi.org/10.1093/jaoac/58.5.1085openalex-snapshot
Methods of Enzymatic Analysis
inferredcites →https://doi.org/10.1093/jb/mvp028openalex-snapshot
A Simple and Immediate Method for Simultaneously Evaluating Expression Level and Plasmid Maintenance in Yeast
inferredcites →https://doi.org/10.1099/00221287-129-4-965openalex-snapshot
An Enzymic Analysis of NADPH Production and Consumption in Candida utilis
inferredcites →https://doi.org/10.1111/j.1365-2672.1992.tb04990.xopenalex-snapshot
Another explanation for the toxicity of fermentation acids at low pH: anion accumulation versus uncoupling
inferredcites →https://doi.org/10.1111/j.1567-1364.2009.00487.xopenalex-snapshot
Effects of acetic acid on the kinetics of xylose fermentation by an engineered, xylose-isomerase-basedSaccharomyces cerevisiaestrain
inferredcites →https://doi.org/10.1126/science.1114736openalex-snapshot
The Path Forward for Biofuels and Biomaterials
inferredcites →https://doi.org/10.1128/aem.01781-07openalex-snapshot
Development of Bottom-Fermenting Saccharomyces Strains That Produce High SO 2 Levels, Using Integrated Metabolome and Transcriptome Analysis
inferredcites →https://doi.org/10.1128/aem.61.12.4184-4190.1995openalex-snapshot
Xylose-metabolizing Saccharomyces cerevisiae strains overexpressing the TKL1 and TAL1 genes encoding the pentose phosphate pathway enzymes transketolase and transaldolase
inferredcites →https://doi.org/10.1128/aem.66.8.3381-3386.2000openalex-snapshot
Anaerobic Xylose Fermentation by Recombinant Saccharomyces cerevisiae Carrying XYL1 , XYL2 , and XKS1 in Mineral Medium Chemostat Cultures
inferredcites →https://doi.org/10.1128/aem.67.3.1163-1170.2001openalex-snapshot
Development of a Saccharomyces cerevisiae Strain with Enhanced Resistance to Phenolic Fermentation Inhibitors in Lignocellulose Hydrolysates by Heterologous Expression of Laccase
inferredcites →https://doi.org/10.1128/aem.69.2.740-746.2003openalex-snapshot
Molecular Analysis of a Saccharomyces cerevisiae Mutant with Improved Ability To Utilize Xylose Shows Enhanced Expression of Proteins Involved in Transport, Initial Xylose Metabolism, and the Pentose Phosphate Pathway
inferredcites →https://doi.org/10.1128/aem.70.4.2307-2317.2004openalex-snapshot
Molecular Basis for Anaerobic Growth of Saccharomyces cerevisiae on Xylose, Investigated by Global Gene Expression and Metabolic Flux Analysis
inferredcites →https://doi.org/10.1128/aem.70.6.3681-3686.2004openalex-snapshot
Endogenous Xylose Pathway in Saccharomyces cerevisiae
inferredcites →https://doi.org/10.1128/aem.71.12.8249-8256.2005openalex-snapshot
Improvement of Xylose Uptake and Ethanol Production in Recombinant Saccharomyces cerevisiae through an Inverse Metabolic Engineering Approach
inferredcites →https://doi.org/10.1128/mmbr.00025-07openalex-snapshot
Progress in Metabolic Engineering of Saccharomyces cerevisiae
inferredcites →https://doi.org/10.1385/abab:129:1:278openalex-snapshot
Effect of Inhibitors Released During Steam-Explosion Pretreatment of Barley Straw on Enzymatic Hydrolysis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Metabolic Engineering Strategies to Enhance Microbial Production of Biopolymers
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Zinc, magnesium, and calcium ion supplementation confers tolerance to acetic acid stress in industrial Saccharomyces cerevisiae utilizing xylose
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Elucidation of ethanol tolerance mechanisms in Saccharomyces cerevisiae by global metabolite profiling
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Combined Cell Surface Display of β‐ d ‐Glucosidase (BGL), Maltose Transporter (MAL11), and Overexpression of Cytosolic Xylose Reductase (XR) in Saccharomyces cerevisiae Enhance Cellobiose/Xylose Coutilization for Xylitol Bioproduction from Lignocellulosic Biomass
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Overexpression of Transcription Factor ZNF1 of Glycolysis Improves Bioethanol Productivity under High Glucose Concentration and Enhances Acetic Acid Tolerance of Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1002/biot.70258openalex-snapshot
Systems‐Level Metabolic Regulation Strategies of Xylose Metabolism in Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1002/bit.24992openalex-snapshot
Comparative metabolic profiling revealed limitations in xylose‐fermenting yeast during co‐fermentation of glucose and xylose in the presence of inhibitors
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The amino‐terminal tail of Hxt11 confers membrane stability to the Hxt2 sugar transporter and improves xylose fermentation in the presence of acetic acid
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Coupled metabolic‐hydrodynamic modeling enabling rational scale‐up of industrial bioprocesses
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Optimization of 1,2,4‐butanetriol production from xylose in Saccharomyces cerevisiae by metabolic engineering of NADH/NADPH balance
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Mass Spectrometry for Metabolomics and Biomass Composition Analyses
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Synthetic Biology and Biofilms
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Bridging Omics Technologies with Synthetic Biology in Yeast Industrial Biotechnology
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Reduction of furan derivatives by overexpressing NADH-dependent Adh1 improves ethanol fermentation using xylose as sole carbon source with Saccharomyces cerevisiae harboring XR–XDH pathway
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Compounds inhibiting the bioconversion of hydrothermally pretreated lignocellulose
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Inverse metabolic engineering based on transient acclimation of yeast improves acid-containing xylose fermentation and tolerance to formic and acetic acids
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Xylose fermentation efficiency and inhibitor tolerance of the recombinant industrial Saccharomyces cerevisiae strain NAPX37
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IoGAS1, a GPI-Anchored Protein Derived from Issatchenkia orientalis, Confers Tolerance of Saccharomyces cerevisiae to Multiple Acids
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Deletion of the PHO13 gene in Saccharomyces cerevisiae improves ethanol production from lignocellulosic hydrolysate in the presence of acetic and formic acids, and furfural
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Sm-like protein enhanced tolerance of recombinant Saccharomyces cerevisiae to inhibitors in hemicellulosic hydrolysate
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Glucose content in the liquid hydrolysate after dilute acid pretreatment is affected by the starch content in rice straw
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RETRACTED: Detoxification of acidic biorefinery waste liquor for production of high value amino acid
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Pretreatment of extruded Napier grass by hydrothermal process with dilute sulfuric acid and fermentation using a cellulose-hydrolyzing and xylose-assimilating yeast for ethanol production
inferred← citeshttps://doi.org/10.1016/j.biortech.2025.132649openalex-snapshot
Single cell protein production of co-culture Kodamaea ohmeri and Lactococcus lactis in corn straw hydrolysate
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2011.10.011openalex-snapshot
Development of yeast cell factories for consolidated bioprocessing of lignocellulose to bioethanol through cell surface engineering
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2013.05.002openalex-snapshot
Flux analysis and metabolomics for systematic metabolic engineering of microorganisms
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2015.08.004openalex-snapshot
White biotechnology: State of the art strategies for the development of biocatalysts for biorefining
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2026.108920openalex-snapshot
Engineering Yarrowia lipolytica as a next-generation biomanufacturing platform for sustainable lignocellulosic biorefineries
inferred← citeshttps://doi.org/10.1016/j.bjm.2016.11.011openalex-snapshot
Inhibitor tolerance of a recombinant flocculating industrial Saccharomyces cerevisiae strain during glucose and xylose co-fermentation
inferred← citeshttps://doi.org/10.1016/j.cbpa.2015.06.004openalex-snapshot
Rational design and evolutional fine tuning of Saccharomyces cerevisiae for biomass breakdown
inferred← citeshttps://doi.org/10.1016/j.ces.2020.115933openalex-snapshot
Intracellular redox manipulation of Zymomonas mobilis for improving tolerance against lignocellulose hydrolysate-derived stress
inferred← citeshttps://doi.org/10.1016/j.copbio.2011.10.014openalex-snapshot
Metabolomics-assisted synthetic biology
inferred← citeshttps://doi.org/10.1016/j.copbio.2014.10.001openalex-snapshot
Biological insights through nontargeted metabolomics
inferred← citeshttps://doi.org/10.1016/j.copbio.2014.12.012openalex-snapshot
Improving conversion yield of fermentable sugars into fuel ethanol in 1st generation yeast-based production processes
inferred← citeshttps://doi.org/10.1016/j.copbio.2016.11.006openalex-snapshot
Recent applications of metabolomics to advance microbial biofuel production
inferred← citeshttps://doi.org/10.1016/j.febslet.2012.02.008openalex-snapshot
Metabolomics methods for the synthetic biology of secondary metabolism
inferred← citeshttps://doi.org/10.1016/j.funbio.2025.101709openalex-snapshot
Impact of complex inhibitors in straw hydrolysates on xylose-fermenting Saccharomyces cerevisiae and inhibitor-tolerant strain construction
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2026.151349openalex-snapshot
Friedelane-type oxidosqualene cyclases in friedelin production: Advances in biosynthesis, functional characterization, structure–function relationships, and engineering strategies
inferred← citeshttps://doi.org/10.1016/j.indcrop.2020.113120openalex-snapshot
Dissecting the role of heterogeneity and hydrothermal pretreatment of sugarcane bagasse in metabolic pathways for biofuels production
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2011.12.013openalex-snapshot
Widely targeted metabolic profiling analysis of yeast central metabolites
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2012.12.007openalex-snapshot
Current metabolomics: Practical applications
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2013.05.027openalex-snapshot
Isolation and characterization of a mutant recombinant Saccharomyces cerevisiae strain with high efficiency xylose utilization
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2013.07.007openalex-snapshot
Co-expression of TAL1 and ADH1 in recombinant xylose-fermenting Saccharomyces cerevisiae improves ethanol production from lignocellulosic hydrolysates in the presence of furfural
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2014.09.004openalex-snapshot
Improved ethanol production from xylose in the presence of acetic acid by the overexpression of the HAA1 gene in Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2015.02.011openalex-snapshot
Metabolomic analysis of acid stress response in Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2016.12.009openalex-snapshot
Synthetic metabolic bypass for a metabolic toggle switch enhances acetyl-CoA supply for isopropanol production by Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2017.03.004openalex-snapshot
Evaluation of Saccharomyces cerevisiae GAS1 with respect to its involvement in tolerance to low pH and salt stress
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2017.05.015openalex-snapshot
Orthogonal partial least squares/projections to latent structures regression-based metabolomics approach for identification of gene targets for improvement of 1-butanol production in Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2017.08.001openalex-snapshot
Selection of yeast Saccharomyces cerevisiae promoters available for xylose cultivation and fermentation
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2018.08.013openalex-snapshot
Metabolome analysis revealed the knockout of glyoxylate shunt as an effective strategy for improvement of 1-butanol production in transgenic Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2021.09.015openalex-snapshot
Dynamic metabolic engineering of Escherichia coli improves fermentation for the production of pyruvate and its derivatives
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2023.10.004openalex-snapshot
Comprehensive metabolic profiling of Geotrichum candidum and comparison with Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2011.06.025openalex-snapshot
Direct ethanol production from hemicellulosic materials of rice straw by use of an engineered yeast strain codisplaying three types of hemicellulolytic enzymes on the surface of xylose-utilizing Saccharomyces cerevisiae cells
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2012.05.021openalex-snapshot
Development of microbial cell factories for bio-refinery through synthetic bioengineering
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2012.10.017openalex-snapshot
Gene expression cross-profiling in genetically modified industrial Saccharomyces cerevisiae strains during high-temperature ethanol production from xylose
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2016.04.005openalex-snapshot
Microaerobic conversion of xylose to ethanol in recombinant Saccharomyces cerevisiae SX6 MUT expressing cofactor-balanced xylose metabolic enzymes and deficient in ALD6
inferred← citeshttps://doi.org/10.1016/j.jprot.2015.09.001openalex-snapshot
Saccharomyces cerevisiae as a model in ecotoxicological studies: A post-genomics perspective
inferred← citeshttps://doi.org/10.1016/j.lwt.2015.12.046openalex-snapshot
GC–MS based metabolomics approach of Kimchi for the understanding of Lactobacillus plantarum fermentation characteristics
inferred← citeshttps://doi.org/10.1016/j.lwt.2022.114035openalex-snapshot
Effects of Cell-Cell Interactions between a. Oryzae and Z. Rouxii on Morphology and Secondary Metabolites
inferred← citeshttps://doi.org/10.1016/j.mimet.2013.04.006openalex-snapshot
Sample preparation for the metabolomics investigation of poly-gamma-glutamate-producing Bacillus licheniformis by GC–MS
inferred← citeshttps://doi.org/10.1016/j.procbio.2012.05.004openalex-snapshot
Consolidated bioprocessing and simultaneous saccharification and fermentation of lignocellulose to ethanol with thermotolerant yeast strains
inferred← citeshttps://doi.org/10.1016/j.procbio.2014.07.017openalex-snapshot
Efficient bioethanol production by overexpression of endogenous Saccharomyces cerevisiae xylulokinase and NADPH-dependent aldose reductase with mutated strictly NADP+-dependent Pichia stipitis xylitol dehydrogenase
inferred← citeshttps://doi.org/10.1016/j.procbio.2021.01.024openalex-snapshot
Metabolomic analysis reveals Kluyveromyces marxianus’s stress responses during high-temperature ethanol fermentation
inferred← citeshttps://doi.org/10.1016/j.renene.2026.126312openalex-snapshot
Technical assessment of Agave sisalana leaves as feedstock for integrated first- and second-generation ethanol production
inferred← citeshttps://doi.org/10.1016/j.rser.2019.109353openalex-snapshot
Progress toward improving ethanol production through decreased glycerol generation in Saccharomyces cerevisiae by metabolic and genetic engineering approaches
inferred← citeshttps://doi.org/10.1016/j.synbio.2020.01.001openalex-snapshot
Biofilm architecture: An emerging synthetic biology target
inferred← citeshttps://doi.org/10.1016/j.synbio.2022.11.001openalex-snapshot
Design and construction of microbial cell factories based on systems biology
inferred← citeshttps://doi.org/10.1016/j.synbio.2024.04.006openalex-snapshot
Biotransformation of ethylene glycol by engineered Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.tibtech.2013.10.003openalex-snapshot
Lignocellulosic ethanol production at high-gravity: challenges and perspectives
inferred← citeshttps://doi.org/10.1016/j.tibtech.2014.03.003openalex-snapshot
Recombinant hyperthermophilic enzyme expression in plants: a novel approach for lignocellulose digestion
inferred← citeshttps://doi.org/10.1016/j.tibtech.2019.07.009openalex-snapshot
Dynamic Metabolomics for Engineering Biology: Accelerating Learning Cycles for Bioproduction
inferred← citeshttps://doi.org/10.1016/j.tim.2011.07.005openalex-snapshot
Applications of systems biology towards microbial fuel production
inferred← citeshttps://doi.org/10.1016/j.ymben.2012.03.004openalex-snapshot
A molecular transporter engineering approach to improving xylose catabolism in Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1016/j.ymben.2014.02.008openalex-snapshot
Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch
inferred← citeshttps://doi.org/10.1016/j.ymben.2015.02.004openalex-snapshot
Enhanced tolerance of Saccharomyces cerevisiae to multiple lignocellulose-derived inhibitors through modulation of spermidine contents
inferred← citeshttps://doi.org/10.1016/j.ymben.2015.04.005openalex-snapshot
Self-induced metabolic state switching by a tunable cell density sensor for microbial isopropanol production
inferred← citeshttps://doi.org/10.1016/j.ymben.2017.04.003openalex-snapshot
Metabolomics-driven approach to solving a CoA imbalance for improved 1-butanol production in Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.ymben.2017.08.002openalex-snapshot
Reconstruction of a metabolic regulatory network in Escherichia coli for purposeful switching from cell growth mode to production mode in direct GABA fermentation from glucose
inferred← citeshttps://doi.org/10.1021/ac302881eopenalex-snapshot
Evaluation and Optimization of Metabolome Sample Preparation Methods for Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c04160openalex-snapshot
Proteomic Profiling and Stress Response in Pediococcus acidilactici under Acetic Acid
inferred← citeshttps://doi.org/10.1021/es201648gopenalex-snapshot
Microbially Mediated Mineral Carbonation: Roles of Phototrophy and Heterotrophy
inferred← citeshttps://doi.org/10.1021/jf305322topenalex-snapshot
Detection of Orally Administered Inositol Stereoisomers in Mouse Blood Plasma and Their Effects on Translocation of Glucose Transporter 4 in Skeletal Muscle Cells
inferred← citeshttps://doi.org/10.1038/nrmicro.2016.32openalex-snapshot
Fuelling the future: microbial engineering for the production of sustainable biofuels
inferred← citeshttps://doi.org/10.1038/s41598-019-41863-1openalex-snapshot
Increased flux in acetyl-CoA synthetic pathway and TCA cycle of Kluyveromyces marxianus under respiratory conditions
inferred← citeshttps://doi.org/10.1038/s41598-022-26686-xopenalex-snapshot
The potential of multistress tolerant yeast, Saccharomycodes ludwigii, for second-generation bioethanol production
inferred← citeshttps://doi.org/10.1038/s41598-023-39661-xopenalex-snapshot
Streamlined identification of strain engineering targets for bioprocess improvement using metabolic pathway enrichment analysis
inferred← citeshttps://doi.org/10.1038/s41598-023-48408-7openalex-snapshot
Adaptive laboratory evolution under acetic acid stress enhances the multistress tolerance and ethanol production efficiency of Pichia kudriavzevii from lignocellulosic biomass
inferred← citeshttps://doi.org/10.1039/c4mt00275jopenalex-snapshot
The impact of zinc sulfate addition on the dynamic metabolic profiling of Saccharomyces cerevisiae subjected to long term acetic acid stress treatment and identification of key metabolites involved in the antioxidant effect of zinc
inferred← citeshttps://doi.org/10.1039/c7ra04049kopenalex-snapshot
Enhanced fuel ethanol production from rice straw hydrolysate by an inhibitor-tolerant mutant strain of Scheffersomyces stipitis
inferred← citeshttps://doi.org/10.1071/ch16022openalex-snapshot
Development of Lignocellulosic Biorefinery Technologies: Recent Advances and Current Challenges
inferred← citeshttps://doi.org/10.1080/1343943x.2017.1389614openalex-snapshot
Overexpression of CO2-responsive CCT protein, a key regulator of starch synthesis strikingly increases the glucose yield from rice straw for bioethanol production
inferred← citeshttps://doi.org/10.1089/ind.2013.0004openalex-snapshot
Prediction of Weak Acid Toxicity in Saccharomyces cerevisiae Using Genome-Scale Metabolic Models
inferred← citeshttps://doi.org/10.1089/ind.2021.0029openalex-snapshot
Effects of Temperature and pH on Salt-Stressed Yeast Cultures in Non-Detoxified Coconut Hydrolysate
inferred← citeshttps://doi.org/10.1093/femsyr/fox061openalex-snapshot
Transporter engineering in biomass utilization by yeast
inferred← citeshttps://doi.org/10.1093/femsyr/foy011openalex-snapshot
Spathaspora passalidarum selected for resistance to AFEX hydrolysate shows decreased cell yield
inferred← citeshttps://doi.org/10.1093/jxb/ert134openalex-snapshot
Dynamic metabolic profiling of cyanobacterial glycogen biosynthesis under conditions of nitrate depletion
inferred← citeshttps://doi.org/10.1093/nar/gkv358openalex-snapshot
ChiNet uncovers rewired transcription subnetworks in tolerant yeast for advanced biofuels conversion
inferred← citeshttps://doi.org/10.1111/j.1567-1364.2011.00771.xopenalex-snapshot
From network models to network responses: integration of thermodynamic and kinetic properties of yeast genome-scale metabolic networks
inferred← citeshttps://doi.org/10.1111/j.1567-1364.2011.00775.xopenalex-snapshot
Evolutionary engineering of Saccharomyces cerevisiae for improved industrially important properties
inferred← citeshttps://doi.org/10.1111/j.1567-1364.2011.00779.xopenalex-snapshot
A systems-level approach for metabolic engineering of yeast cell factories
inferred← citeshttps://doi.org/10.11118/978-80-7701-093-1-0138openalex-snapshot
INVOLVEMENT OF 4-PENTENOIC ACID IN CAUSING QUALITY DETERIORATION OF NETTLE SILAGE: STUDY OF ANTIBACTERIAL MECHANISM
inferred← citeshttps://doi.org/10.11606/t.97.2020.tde-29012020-154552openalex-snapshot
Produção de etanol celulósico por >i /i< a partir do bagaço de cana-de-açúcar: estratégia para melhorar fermentabilidade e estudo do perfil metabólico durante fermentação de hidrolisado hemicelulósico
inferred← citeshttps://doi.org/10.1186/1475-2859-10-5openalex-snapshot
Xylitol production from xylose mother liquor: a novel strategy that combines the use of recombinant Bacillus subtilis and Candida maltosa
inferred← citeshttps://doi.org/10.1186/1475-2859-10-69openalex-snapshot
A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's disease
inferred← citeshttps://doi.org/10.1186/1475-2859-11-156openalex-snapshot
Systems metabolic engineering, industrial biotechnology and microbial cell factories
inferred← citeshttps://doi.org/10.1186/1475-2859-12-113openalex-snapshot
Bacterial cell factories for recombinant protein production; expanding the catalogue
inferred← citeshttps://doi.org/10.1186/1475-2859-13-64openalex-snapshot
Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli
inferred← citeshttps://doi.org/10.1186/1754-6834-6-16openalex-snapshot
Bioconversion of lignocellulose: inhibitors and detoxification
inferred← citeshttps://doi.org/10.1186/1756-0500-6-201openalex-snapshot
PCR on yeast colonies: an improved method for glyco-engineered Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1186/preaccept-5300899441378705openalex-snapshot
Development of a GIN11/FRT-based multiple-gene integration technique affording inhibitor-tolerant, hemicellulolytic, xylose-utilizing abilities to industrial Saccharomyces cerevisiae strains for ethanol production from undetoxified lignocellulosic hemicelluloses
inferred← citeshttps://doi.org/10.1186/s12864-019-5959-8openalex-snapshot
Natural allelic variations of Saccharomyces cerevisiae impact stuck fermentation due to the combined effect of ethanol and temperature; a QTL-mapping study
inferred← citeshttps://doi.org/10.1186/s12866-015-0373-0openalex-snapshot
Hyperphosphorylation of DegU cancels CcpA-dependent catabolite repression of rocG in Bacillus subtilis
inferred← citeshttps://doi.org/10.1186/s12934-014-0151-yopenalex-snapshot
Metabolomic basis of laboratory evolution of butanol tolerance in photosynthetic Synechocystis sp. PCC 6803
inferred← citeshttps://doi.org/10.1186/s12934-015-0240-6openalex-snapshot
Eliminating the isoleucine biosynthetic pathway to reduce competitive carbon outflow during isobutanol production by Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1186/s12934-015-0242-4openalex-snapshot
Engineering Saccharomyces pastorianus for the co-utilisation of xylose and cellulose from biomass
inferred← citeshttps://doi.org/10.1186/s12934-016-0465-zopenalex-snapshot
Improving ethanol yield in acetate-reducing Saccharomyces cerevisiae by cofactor engineering of 6-phosphogluconate dehydrogenase and deletion of ALD6
inferred← citeshttps://doi.org/10.1186/s12934-018-0927-6openalex-snapshot
Metabolome analysis-based design and engineering of a metabolic pathway in Corynebacterium glutamicum to match rates of simultaneous utilization of d-glucose and l-arabinose
inferred← citeshttps://doi.org/10.1186/s12934-018-0998-4openalex-snapshot
Widespread effect of N-acetyl-d-glucosamine assimilation on the metabolisms of amino acids, purines, and pyrimidines in Scheffersomyces stipitis
inferred← citeshttps://doi.org/10.1186/s12934-021-01596-1openalex-snapshot
Stepwise metabolic engineering of Candida tropicalis for efficient xylitol production from xylose mother liquor
inferred← citeshttps://doi.org/10.1186/s12934-026-02987-yopenalex-snapshot
Response mechanisms of xylitol-producing Saccharomyces cerevisiae strains to acetic acid and furfural and the role of SPI1, CTT1, and CLB1 in tolerance
inferred← citeshttps://doi.org/10.1186/s13068-015-0258-3openalex-snapshot
Tolerance and adaptive evolution of triacylglycerol-producing Rhodococcus opacus to lignocellulose-derived inhibitors
inferred← citeshttps://doi.org/10.1186/s13068-015-0329-5openalex-snapshot
Increasing proline and myo-inositol improves tolerance of Saccharomyces cerevisiae to the mixture of multiple lignocellulose-derived inhibitors
inferred← citeshttps://doi.org/10.1186/s13068-015-0421-xopenalex-snapshot
Polygenic analysis and targeted improvement of the complex trait of high acetic acid tolerance in the yeast Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1186/s13068-016-0583-1openalex-snapshot
A new laboratory evolution approach to select for constitutive acetic acid tolerance in Saccharomyces cerevisiae and identification of causal mutations
inferred← citeshttps://doi.org/10.1186/s13068-017-0781-5openalex-snapshot
Genome-wide search for candidate genes for yeast robustness improvement against formic acid reveals novel susceptibility (Trk1 and positive regulators) and resistance (Haa1-regulon) determinants
inferred← citeshttps://doi.org/10.1186/s13068-019-1643-0openalex-snapshot
Structure-based directed evolution improves S. cerevisiae growth on xylose by influencing in vivo enzyme performance
inferred← citeshttps://doi.org/10.1186/s13068-020-01833-6openalex-snapshot
Engineering prokaryotic regulator IrrE to enhance stress tolerance in budding yeast
inferred← citeshttps://doi.org/10.1186/s13068-021-01935-9openalex-snapshot
Identification of the major fermentation inhibitors of recombinant 2G yeasts in diverse lignocellulose hydrolysates
inferred← citeshttps://doi.org/10.1186/s13568-015-0175-7openalex-snapshot
Disruption of PHO13 improves ethanol production via the xylose isomerase pathway
inferred← citeshttps://doi.org/10.1186/s13568-016-0210-3openalex-snapshot
Metabolome analysis of Saccharomyces cerevisiae and optimization of culture medium for S-adenosyl-l-methionine production
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