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Chronic Palmitate But Not Oleate Exposure Induces Endoplasmic Reticulum Stress, Which May Contribute to INS-1 Pancreatic β-Cell Apoptosis
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/jcp.10187openalex-snapshot
Pleiotropic effects of fatty acids on pancreatic β‐cells
inferredcites →https://doi.org/10.1002/jemt.1060160110openalex-snapshot
Improved uranyl acetate staining for electron microscopy
inferredcites →https://doi.org/10.1007/bf02473201openalex-snapshot
Improving structural integrity of cryosections for immunogold labeling
inferredcites →https://doi.org/10.1007/s00125-005-1861-9openalex-snapshot
Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro
inferredcites →https://doi.org/10.1007/s001250100021openalex-snapshot
A choice of death - the signal-transduction of immune-mediated beta-cell apoptosis
inferredcites →https://doi.org/10.1016/0143-4160(85)90041-7openalex-snapshot
Measurement of cytosolic free Ca2+ in individual small cells using fluorescence microscopy with dual excitation wavelengths
inferredcites →https://doi.org/10.1016/j.jchemneu.2004.05.004openalex-snapshot
Survival and apoptosis signals in ER stress: the role of protein kinases
inferredcites →https://doi.org/10.1016/j.jchemneu.2004.05.008openalex-snapshot
Caspases involved in ER stress-mediated cell death
inferredcites →https://doi.org/10.1016/s0006-2952(02)00860-2openalex-snapshot
Troglitazone does not protect rat pancreatic β cells against free fatty acid-induced cytotoxicity
inferredcites →https://doi.org/10.1016/s0008-6363(99)00384-3openalex-snapshot
Morphologic and biochemical hallmarks of apoptosis
inferredcites →https://doi.org/10.1016/s0021-9258(19)47340-7openalex-snapshot
Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps.
inferredcites →https://doi.org/10.1016/s0092-8674(00)00039-8openalex-snapshot
Megavesicles Implicated in the Rapid Transport of Intracisternal Aggregates across the Golgi Stack
inferredcites →https://doi.org/10.1016/s0092-8674(01)00611-0openalex-snapshot
XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor
inferredcites →https://doi.org/10.1016/s1097-2765(00)00108-8openalex-snapshot
Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells
inferredcites →https://doi.org/10.1016/s1388-1981(02)00342-6openalex-snapshot
Lipoapoptosis: its mechanism and its diseases
inferredcites →https://doi.org/10.1016/s1534-5807(02)00203-4openalex-snapshot
ER Stress Regulation of ATF6 Localization by Dissociation of BiP/GRP78 Binding and Unmasking of Golgi Localization Signals
inferredcites →https://doi.org/10.1038/16729openalex-snapshot
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
inferredcites →https://doi.org/10.1038/35014014openalex-snapshot
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
inferredcites →https://doi.org/10.1038/415092aopenalex-snapshot
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
inferredcites →https://doi.org/10.1038/nm1259openalex-snapshot
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis
inferredcites →https://doi.org/10.1038/sj.cdd.4401373openalex-snapshot
Roles of CHOP/GADD153 in endoplasmic reticulum stress
inferredcites →https://doi.org/10.1053/meta.2002.35200openalex-snapshot
Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: Possible role of oxidative stress
inferredcites →https://doi.org/10.1073/pnas.95.5.2498openalex-snapshot
Fatty acid-induced β cell apoptosis: A link between obesity and diabetes
inferredcites →https://doi.org/10.1073/pnas.96.5.2327openalex-snapshot
Regulation of fatty acid homeostasis in cells: Novel role of leptin
inferredcites →https://doi.org/10.1074/jbc.m110636200openalex-snapshot
The Luminal Domain of ATF6 Senses Endoplasmic Reticulum (ER) Stress and Causes Translocation of ATF6 from the ER to the Golgi
inferredcites →https://doi.org/10.1074/jbc.m208756200openalex-snapshot
Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic β-Cells (INS-1)
inferredcites →https://doi.org/10.1074/jbc.m410876200openalex-snapshot
Proteasome Inhibition Alters Glucose-stimulated (Pro)insulin Secretion and Turnover in Pancreatic β-Cells
inferredcites →https://doi.org/10.1074/jbc.r400008200openalex-snapshot
Signaling the Unfolded Protein Response from the Endoplasmic Reticulum
inferredcites →https://doi.org/10.1091/mbc.10.11.3787openalex-snapshot
Mammalian Transcription Factor ATF6 Is Synthesized as a Transmembrane Protein and Activated by Proteolysis in Response to Endoplasmic Reticulum Stress
inferredcites →https://doi.org/10.1093/jb/mvh122openalex-snapshot
Differential Contributions of ATF6 and XBP1 to the Activation of Endoplasmic Reticulum Stress-Responsive cis-Acting Elements ERSE, UPRE and ERSE-II
inferredcites →https://doi.org/10.1101/gad.1250704openalex-snapshot
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
inferredcites →https://doi.org/10.1126/science.1103160openalex-snapshot
Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes
inferredcites →https://doi.org/10.1126/science.287.5453.664openalex-snapshot
Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1
inferredcites →https://doi.org/10.1128/mcb.20.14.5096-5106.2000openalex-snapshot
ATF6 as a Transcription Activator of the Endoplasmic Reticulum Stress Element: Thapsigargin Stress-Induced Changes and Synergistic Interactions with NF-Y and YY1
inferredcites →https://doi.org/10.1146/annurev.cellbio.18.011402.160624openalex-snapshot
Transcriptional and Translational Control in the Mammalian Unfolded Protein Response
inferredcites →https://doi.org/10.1146/annurev.med.47.1.69openalex-snapshot
AN INTEGRATED VIEW OF β-CELL DYSFUNCTION IN TYPE-II DIABETES
inferredcites →https://doi.org/10.1172/jci119534openalex-snapshot
Role of nitric oxide in obesity-induced beta cell disease.
inferredcites →https://doi.org/10.1177/153537020322801018openalex-snapshot
Impact of Endoplasmic Reticulum Stress Pathway on Pancreatic β-Cells and Diabetes Mellitus
inferredcites →https://doi.org/10.1210/en.130.1.167openalex-snapshot
Establishment of 2-mercaptoethanol-dependent differentiated insulin- secreting cell lines
inferredcites →https://doi.org/10.1210/en.140.8.3422openalex-snapshot
Sodium Palmitate Induces Partial Mitochondrial Uncoupling and Reactive Oxygen Species in Rat Pancreatic Islets in Vitro
inferredcites →https://doi.org/10.1210/en.142.11.4777openalex-snapshot
The Effect of Chronic Exposure to Fatty Acids on Gene Expression in Clonal Insulin-Producing Cells: Studies Using High Density Oligonucleotide Microarray
inferredcites →https://doi.org/10.1210/en.2001-211282openalex-snapshot
Mitochondrial Dysfunction Is Involved in Apoptosis Induced by Serum Withdrawal and Fatty Acids in the β-Cell Line Ins-1
inferredcites →https://doi.org/10.1210/en.2004-0478openalex-snapshot
Free Fatty Acids and Cytokines Induce Pancreatic β-Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor-κB and Endoplasmic Reticulum Stress
inferredcites →https://doi.org/10.1210/endo.140.8.6908openalex-snapshot
Sodium Palmitate Induces Partial Mitochondrial Uncoupling and Reactive Oxygen Species in Rat Pancreatic Isletsin Vitro1
inferredcites →https://doi.org/10.1210/endo.142.1.7863openalex-snapshot
Free Fatty Acid-Induced Inhibition of Glucose and Insulin-Like Growth Factor I-Induced Deoxyribonucleic Acid Synthesis in the Pancreatic β-Cell Line INS-11
inferredcites →https://doi.org/10.2174/1566524053766004openalex-snapshot
Type 2 Diabetes, Insulin Secretion and β-Cell Mass
inferredcites →https://doi.org/10.2337/diab.44.8.863openalex-snapshot
Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications
inferredcites →https://doi.org/10.2337/diabetes.50.1.69openalex-snapshot
Distinct Effects of Saturated and Monounsaturated Fatty Acids on β-Cell Turnover and Function
inferredcites →https://doi.org/10.2337/diabetes.50.2007.s118openalex-snapshot
Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover.
inferredcites →https://doi.org/10.2337/diabetes.50.8.1771openalex-snapshot
Inverse Relationship Between Cytotoxicity of Free Fatty Acids in Pancreatic Islet Cells and Cellular Triglyceride Accumulation
inferredcites →https://doi.org/10.2337/diabetes.51.2007.s455openalex-snapshot
Endoplasmic Reticulum Stress and the Development of Diabetes
inferredcites →https://doi.org/10.2337/diabetes.51.4.977openalex-snapshot
Expression Profiling of Palmitate- and Oleate-Regulated Genes Provides Novel Insights Into the Effects of Chronic Lipid Exposure on Pancreatic β-Cell Function
inferredcites →https://doi.org/10.2337/diabetes.52.3.726openalex-snapshot
Monounsaturated Fatty Acids Prevent the Deleterious Effects of Palmitate and High Glucose on Human Pancreatic β-Cell Turnover and Function
inferredcites →https://doi.org/10.2337/diabetes.53.1.129openalex-snapshot
Gene and Protein Kinase Expression Profiling of Reactive Oxygen Species-Associated Lipotoxicity in the Pancreatic β-Cell Line MIN6
inferredcites →https://doi.org/10.2337/diabetes.53.2007.s119openalex-snapshot
β-Cell Glucose Toxicity, Lipotoxicity, and Chronic Oxidative Stress in Type 2 Diabetes
inferredcites →https://doi.org/10.2337/diabetes.54.4.968openalex-snapshot
Endoplasmic Reticulum Stress–Induced Apoptosis Is Partly Mediated by Reduced Insulin Signaling Through Phosphatidylinositol 3-Kinase/Akt and Increased Glycogen Synthase Kinase-3β in Mouse Insulinoma Cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Protein-Rich Foods, Sea Foods, and Gut Microbiota Amplify Immune Responses in Chronic Diseases and Cancers – Targeting Perk as a Novel Therapeutic Strategy for Cancer
inferred← citeshttps://doi.org/10.1002/9783527628100.ch21openalex-snapshot
Nutrient‐Derived Endogenous Toxins in the Pathogenesis of Type 2 Diabetes at the β‐Cell Level
inferred← citeshttps://doi.org/10.1002/cbf.3067openalex-snapshot
Binding of polyunsaturated fatty acids to LXRα and modulation of SREBP‐1 interaction with a specific SCD1 promoter element
inferred← citeshttps://doi.org/10.1002/dmrr.1132openalex-snapshot
Diabetes as a disease of endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.1002/dmrr.1295openalex-snapshot
Cell death‐inducing DFF45‐like effector b (Cideb) is present in pancreatic beta‐cells and involved in palmitate induced beta‐cell apoptosis
inferred← citeshttps://doi.org/10.1002/dmrr.896openalex-snapshot
Gene expression regulated by pioglitazone and exenatide in normal and diabetic rat islets exposed to lipotoxicity
inferred← citeshttps://doi.org/10.1002/ehf2.14224openalex-snapshot
Diabetic Cardiomyopathy: A Brief Summary on Lipid Toxicity
inferred← citeshttps://doi.org/10.1002/ejlt.201100309openalex-snapshot
Beta‐cell injury in Ncb5or‐null mice is exacerbated by consumption of a high‐fat diet
inferred← citeshttps://doi.org/10.1002/ejlt.201200058openalex-snapshot
High fat feeding exacerbates endoplasmic reticulum stress and beta cell demise
inferred← citeshttps://doi.org/10.1002/hep.25601openalex-snapshot
Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice
inferred← citeshttps://doi.org/10.1002/jcb.21701openalex-snapshot
Protective effects of R‐alpha‐lipoic acid and acetyl‐ L ‐carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid
inferred← citeshttps://doi.org/10.1002/jcb.22734openalex-snapshot
Fatty acid‐induced oxidation and triglyceride formation is higher in insulin‐producing MIN6 cells exposed to oleate compared to palmitate
inferred← citeshttps://doi.org/10.1002/jcb.23450openalex-snapshot
Inhibition of GPR40 protects MIN6 β cells from palmitate‐induced ER stress and apoptosis
inferred← citeshttps://doi.org/10.1002/jcb.24032openalex-snapshot
Thapsigargin down‐regulates protein levels of GRP78/BiP in INS‐1E cells
inferred← citeshttps://doi.org/10.1002/jcp.22255openalex-snapshot
Cannabinoid receptor 1 mediates palmitic acid‐induced apoptosis via endoplasmic reticulum stress in human renal proximal tubular cells
inferred← citeshttps://doi.org/10.1002/jev2.12232openalex-snapshot
A multi‐omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
inferred← citeshttps://doi.org/10.1002/jsfa.7764openalex-snapshot
Effect of prebiotics of Agave salmiana fed to healthy Wistar rats
inferred← citeshttps://doi.org/10.1002/lipd.70005openalex-snapshot
Solubilization of Saturated Fatty Acids and Its Lysophosphatidylcholine by Complexation With Bovine Serum Albumin
inferred← citeshttps://doi.org/10.1002/mnfr.201700737openalex-snapshot
Sulforaphane Improves Abnormal Lipid Metabolism via Both ERS‐Dependent XBP1/ACC &SCD1 and ERS‐Independent SREBP/FAS Pathways
inferred← citeshttps://doi.org/10.1002/mnfr.201900183openalex-snapshot
Targeting PLIN2/PLIN5‐PPARγ: Sulforaphane Disturbs the Maturation of Lipid Droplets
inferred← citeshttps://doi.org/10.1002/mnfr.202001076openalex-snapshot
Sulforaphane Balances Ca 2+ Homeostasis Injured by Excessive Fat via Mitochondria‐Associated Membrane (MAM)
inferred← citeshttps://doi.org/10.1007/978-1-4020-9701-0_4openalex-snapshot
Chronic Inflammation in the Metabolic Syndrome: Emphasis on Adipose Tissue
inferred← citeshttps://doi.org/10.1007/978-3-030-05067-2_7openalex-snapshot
The Unfolded Protein Response in Triple-Negative Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-3-030-11488-6_5openalex-snapshot
Unfolded Protein Response: Cause or Consequence of Lipid and Lipoprotein Metabolism Disturbances?
inferred← citeshttps://doi.org/10.1007/978-3-030-49844-3_8openalex-snapshot
Protein Kinases Signaling in Pancreatic Beta-cells Death and Type 2 Diabetes
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The Taurine-Conjugated Bile Acid (TUDCA) Normalizes Insulin Secretion in Pancreatic β-Cells Exposed to Fatty Acids: The Role of Mitochondrial Metabolism
inferred← citeshttps://doi.org/10.1007/978-3-031-63657-8_13openalex-snapshot
Endoplasmic Reticulum Stress and Obesity
inferred← citeshttps://doi.org/10.1007/978-3-031-63657-8_16openalex-snapshot
The Mechanism of Leptin Resistance in Obesity and Therapeutic Perspective
inferred← citeshttps://doi.org/10.1007/978-3-319-01008-3_5openalex-snapshot
The Beta Cell in Metabolic Syndrome
inferred← citeshttps://doi.org/10.1007/978-3-319-48382-5_11openalex-snapshot
Endoplasmic Reticulum Stress and Obesity
inferred← citeshttps://doi.org/10.1007/978-3-319-48382-5_16openalex-snapshot
Diet-Induced Obesity and the Mechanism of Leptin Resistance
inferred← citeshttps://doi.org/10.1007/978-4-431-75452-7_12openalex-snapshot
Regulation of Beta-Cell Growth and Death
inferred← citeshttps://doi.org/10.1007/978-94-007-4351-9_9openalex-snapshot
Pathological ER Stress in β Cells
inferred← citeshttps://doi.org/10.1007/s00018-009-0049-8openalex-snapshot
Intersection of the unfolded protein response and hepatic lipid metabolism
inferred← citeshttps://doi.org/10.1007/s00125-006-0590-zopenalex-snapshot
Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes
inferred← citeshttps://doi.org/10.1007/s00125-007-0609-0openalex-snapshot
Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs
inferred← citeshttps://doi.org/10.1007/s00125-007-0674-4openalex-snapshot
Acute nutrient regulation of the unfolded protein response and integrated stress response in cultured rat pancreatic islets
inferred← citeshttps://doi.org/10.1007/s00125-007-0816-8openalex-snapshot
The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients
inferred← citeshttps://doi.org/10.1007/s00125-009-1506-5openalex-snapshot
Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload
inferred← citeshttps://doi.org/10.1007/s00125-010-1833-6openalex-snapshot
Neuronal nitric oxide synthase protects the pancreatic beta cell from glucolipotoxicity-induced endoplasmic reticulum stress and apoptosis
inferred← citeshttps://doi.org/10.1007/s00125-010-1958-7openalex-snapshot
Translationally controlled tumour protein (TCTP) is a novel glucose-regulated protein that is important for survival of pancreatic beta cells
inferred← citeshttps://doi.org/10.1007/s00125-012-2643-9openalex-snapshot
Identification of direct forkhead box O1 targets involved in palmitate-induced apoptosis in clonal insulin-secreting cells using chromatin immunoprecipitation coupled to DNA selection and ligation
inferred← citeshttps://doi.org/10.1007/s00125-015-3563-2openalex-snapshot
The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells
inferred← citeshttps://doi.org/10.1007/s00125-017-4310-7openalex-snapshot
HSF1 acetylation decreases its transcriptional activity and enhances glucolipotoxicity-induced apoptosis in rat and human beta cells
inferred← citeshttps://doi.org/10.1007/s00441-009-0926-3openalex-snapshot
Oleate and linoleate stimulate degradation of β-casein in prolactin-treated HC11 mouse mammary epithelial cells
inferred← citeshttps://doi.org/10.1007/s00775-011-0780-0openalex-snapshot
Vanadyl bisacetylacetonate protects β cells from palmitate-induced cell death through the unfolded protein response pathway
inferred← citeshttps://doi.org/10.1007/s10068-010-0029-7openalex-snapshot
Anticancer effect of lipids partially purified from Pacific oyster, Crassostrea gigas on PC3 cells
inferred← citeshttps://doi.org/10.1007/s10495-008-0298-2openalex-snapshot
Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer
inferred← citeshttps://doi.org/10.1007/s10495-009-0352-8openalex-snapshot
Diabetes and apoptosis: lipotoxicity
inferred← citeshttps://doi.org/10.1007/s10495-011-0576-2openalex-snapshot
CHOP deletion does not impact the development of diabetes but suppresses the early production of insulin autoantibody in the NOD mouse
inferred← citeshttps://doi.org/10.1007/s10495-014-1021-0openalex-snapshot
ClC-3 deficiency protects preadipocytes against apoptosis induced by palmitate in vitro and in type 2 diabetes mice
inferred← citeshttps://doi.org/10.1007/s10495-015-1150-0openalex-snapshot
Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways
inferred← citeshttps://doi.org/10.1007/s10495-019-01587-zopenalex-snapshot
Artemisinin and dihydroartemisinin promote β-cell apoptosis induced by palmitate via enhancing ER stress
inferred← citeshttps://doi.org/10.1007/s10565-008-9067-9openalex-snapshot
Effects of ethanol on pancreatic beta-cell death: interaction with glucose and fatty acids
inferred← citeshttps://doi.org/10.1007/s11010-007-9461-2openalex-snapshot
Saturated fatty acid-mediated endoplasmic reticulum stress and apoptosis are augmented by trans-10, cis-12-conjugated linoleic acid in liver cells
inferred← citeshttps://doi.org/10.1007/s11010-009-0142-1openalex-snapshot
Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells
inferred← citeshttps://doi.org/10.1007/s11010-011-1211-9openalex-snapshot
Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway
inferred← citeshttps://doi.org/10.1007/s11010-015-2387-1openalex-snapshot
SEAP activity serves for demonstrating ER stress induction by glucolipotoxicity as well as testing ER stress inhibitory potential of therapeutic agents
inferred← citeshttps://doi.org/10.1007/s11102-024-01477-xopenalex-snapshot
Treatment of acromegaly-induced diabetes: an updated proposal
inferred← citeshttps://doi.org/10.1007/s11154-008-9101-5openalex-snapshot
β-cell failure as a complication of diabetes
inferred← citeshttps://doi.org/10.1007/s11154-021-09664-yopenalex-snapshot
Extracellular vesicles—incorporated microRNA signature as biomarker and diagnosis of prediabetes state and its complications
inferred← citeshttps://doi.org/10.1007/s11377-009-0373-4openalex-snapshot
Neue Aspekte zur Pathogenese der NASH
inferred← citeshttps://doi.org/10.1007/s11596-011-0249-yopenalex-snapshot
Genistein reverses free fatty acid-induced insulin resistance in HepG2 hepatocytes through targeting JNK
inferred← citeshttps://doi.org/10.1007/s11883-014-0455-8openalex-snapshot
Lipidomic Profiling at the Interface of Metabolic Surgery and Cardiovascular Disease
inferred← citeshttps://doi.org/10.1007/s11906-007-0084-5openalex-snapshot
Lipid-induced cell dysfunction and cell death: Lessons from yeast
inferred← citeshttps://doi.org/10.1007/s12020-010-9432-3openalex-snapshot
Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways
inferred← citeshttps://doi.org/10.1007/s12020-012-9633-zopenalex-snapshot
Mitochondrial reactive oxygen species (ROS) inhibition ameliorates palmitate-induced INS-1 beta cell death
inferred← citeshttps://doi.org/10.1007/s12020-012-9826-5openalex-snapshot
Rosiglitazone protects against palmitate-induced pancreatic beta-cell death by activation of autophagy via 5′-AMP-activated protein kinase modulation
inferred← citeshttps://doi.org/10.1007/s12020-015-0531-zopenalex-snapshot
Implications of ghrelin and hexarelin in diabetes and diabetes-associated heart diseases
inferred← citeshttps://doi.org/10.1007/s12031-010-9383-4openalex-snapshot
Intra-Islet PACAP Protects Pancreatic β-Cells Against Glucotoxicity and Lipotoxicity
inferred← citeshttps://doi.org/10.1007/s12192-018-0893-2openalex-snapshot
Scopoletin intervention in pancreatic endoplasmic reticulum stress induced by lipotoxicity
inferred← citeshttps://doi.org/10.1007/s13238-016-0258-5openalex-snapshot
Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival
inferred← citeshttps://doi.org/10.1007/s43440-020-00101-6openalex-snapshot
Chronic activation of GPR40 does not negatively impact upon BRIN-BD11 pancreatic β-cell physiology and function
inferred← citeshttps://doi.org/10.1016/b978-0-12-800174-5.00011-9openalex-snapshot
Cellular Inhibitor of Apoptosis Protein-1 and Survival of Beta Cells Undergoing Endoplasmic Reticulum Stress
inferred← citeshttps://doi.org/10.1016/b978-0-12-811297-7.00027-5openalex-snapshot
Strategies to Counter Saturated Fatty Acid (SFA)-Mediated Lipointoxication
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2021.02.013openalex-snapshot
Molecular mechanisms of lipotoxicity-induced pancreatic β-cell dysfunction
inferred← citeshttps://doi.org/10.1016/j.abb.2008.04.015openalex-snapshot
A chemical chaperone 4-PBA ameliorates palmitate-induced inhibition of glucose-stimulated insulin secretion (GSIS)
inferred← citeshttps://doi.org/10.1016/j.abb.2010.10.011openalex-snapshot
Supplement of TCA cycle intermediates protects against high glucose/palmitate-induced INS-1 beta cell death
inferred← citeshttps://doi.org/10.1016/j.abb.2014.11.009openalex-snapshot
Downregulation of adipose triglyceride lipase promotes cardiomyocyte hypertrophy by triggering the accumulation of ceramides
inferred← citeshttps://doi.org/10.1016/j.arteri.2014.02.003openalex-snapshot
PPARα atenúa el estrés del retículo endoplasmático inducido por palmitato en células cardíacas humanas por medio de la inducción de la actividad AMPK
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2012.11.003openalex-snapshot
The regional ratio of cholesteryl palmitate to cholesteryl oleate measured by ToF-SIMS as a key parameter of atherosclerosis
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2017.09.004openalex-snapshot
Stearic acid at physiologic concentrations induces in vitro lipotoxicity in circulating angiogenic cells
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2024.118623openalex-snapshot
Role of fatty acids in the pathogenesis of ß-cell failure and Type-2 diabetes
inferred← citeshttps://doi.org/10.1016/j.bbadis.2011.07.016openalex-snapshot
Development of diabetes in lean Ncb5or-null mice is associated with manifestations of endoplasmic reticulum and oxidative stress in beta cells
inferred← citeshttps://doi.org/10.1016/j.bbadis.2014.12.021openalex-snapshot
Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic cells
inferred← citeshttps://doi.org/10.1016/j.bbadis.2015.02.012openalex-snapshot
Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet
inferred← citeshttps://doi.org/10.1016/j.bbadis.2017.06.003openalex-snapshot
Lipid-induced endoplasmic reticulum stress in X-linked adrenoleukodystrophy
inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.06.021openalex-snapshot
Modulation of cellular membrane properties as a potential therapeutic strategy to counter lipointoxication in obstructive pulmonary diseases
inferred← citeshttps://doi.org/10.1016/j.bbalip.2009.08.006openalex-snapshot
Glucolipotoxicity of the pancreatic beta cell
inferred← citeshttps://doi.org/10.1016/j.bbalip.2009.09.006openalex-snapshot
Drosophila as a lipotoxicity model organism — more than a promise?
inferred← citeshttps://doi.org/10.1016/j.bbalip.2009.12.016openalex-snapshot
Obese and anorexic yeasts: Experimental models to understand the metabolic syndrome and lipotoxicity
inferred← citeshttps://doi.org/10.1016/j.bbalip.2016.06.012openalex-snapshot
Oleate protects beta-cells from the toxic effect of palmitate by activating pro-survival pathways of the ER stress response
inferred← citeshttps://doi.org/10.1016/j.bbalip.2017.11.006openalex-snapshot
Cell culture models of fatty acid overload: Problems and solutions
inferred← citeshttps://doi.org/10.1016/j.bbalip.2019.06.002openalex-snapshot
Sphingolipids and the unfolded protein response
inferred← citeshttps://doi.org/10.1016/j.bbalip.2024.159452openalex-snapshot
Protective effect of oleic acid against very long-chain fatty acid-induced apoptosis in peroxisome-deficient CHO cells
inferred← citeshttps://doi.org/10.1016/j.bbalip.2025.159670openalex-snapshot
Different effects of Lorenzo's oil components against very long-chain fatty acid-induced endoplasmic reticulum stress in peroxisome-deficient CHO cells
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2021.119138openalex-snapshot
Site-1 and site-2 proteases: A team of two in regulated proteolysis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.08.013openalex-snapshot
Glucolipotoxicity in INS-1E cells is counteracted by carnitine palmitoyltransferase 1 over-expression
inferred← citeshttps://doi.org/10.1016/j.bbrc.2011.11.073openalex-snapshot
Metformin prevents endoplasmic reticulum stress-induced apoptosis through AMPK-PI3K-c-Jun NH2 pathway
inferred← citeshttps://doi.org/10.1016/j.bbrc.2011.11.118openalex-snapshot
Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice
inferred← citeshttps://doi.org/10.1016/j.bbrc.2012.08.072openalex-snapshot
Role of ERp46 in β-cell lipoapoptosis through endoplasmic reticulum stress pathway as well as the protective effect of exendin-4
inferred← citeshttps://doi.org/10.1016/j.bbrc.2013.10.130openalex-snapshot
Oleate rescues INS-1E β-cells from palmitate-induced apoptosis by preventing activation of the unfolded protein response
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.05.057openalex-snapshot
LNK deficiency aggravates palmitate-induced preadipocyte apoptosis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.153773openalex-snapshot
ER stress: A putative therapeutic target for diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.bcp.2014.08.013openalex-snapshot
Free fatty acids as modulators of the NLRP3 inflammasome in obesity/type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.biocel.2008.08.006openalex-snapshot
Endoplasmic reticulum stress underlying the pro-apoptotic effect of epigallocatechin gallate in mouse hepatoma cells
inferred← citeshttps://doi.org/10.1016/j.biochi.2010.04.005openalex-snapshot
Preparation and functional analysis of recombinant protein transduction domain-metallothionein fusion proteins
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.110769openalex-snapshot
Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.111315openalex-snapshot
Adipose tissue and insulin resistance in obese
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114776openalex-snapshot
Cordycepin protects islet β-cells against glucotoxicity and lipotoxicity via modulating related proteins of ROS/JNK signaling pathway
inferred← citeshttps://doi.org/10.1016/j.bpj.2023.03.001openalex-snapshot
Palmitate-mediated disruption of the endoplasmic reticulum decreases intracellular vesicle motility
inferred← citeshttps://doi.org/10.1016/j.brainres.2010.11.013openalex-snapshot
Hyperglycemia magnifies Schwann cell dysfunction and cell death triggered by PA-induced lipotoxicity
inferred← citeshttps://doi.org/10.1016/j.brainres.2011.08.059openalex-snapshot
AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells
inferred← citeshttps://doi.org/10.1016/j.canlet.2023.216352openalex-snapshot
Fatty acids in cancer chemoresistance
inferred← citeshttps://doi.org/10.1016/j.cca.2012.10.001openalex-snapshot
Age-related distributions of nine fasting plasma free fatty acids in a population of Chinese adults
inferred← citeshttps://doi.org/10.1016/j.ceb.2010.11.005openalex-snapshot
The binary switch that controls the life and death decisions of ER stressed β cells
inferred← citeshttps://doi.org/10.1016/j.ceca.2024.102961openalex-snapshot
ER stress as a sentinel mechanism for ER Ca2+ homeostasis
inferred← citeshttps://doi.org/10.1016/j.cell.2015.06.006openalex-snapshot
ER Stress in Dendritic Cells Promotes Cancer
inferred← citeshttps://doi.org/10.1016/j.cellsig.2018.03.013openalex-snapshot
Caveolin-1 deficiency protects pancreatic β cells against palmitate-induced dysfunction and apoptosis
inferred← citeshttps://doi.org/10.1016/j.cellsig.2022.110535openalex-snapshot
ATF5 is a regulator of ER stress and β-cell apoptosis in different mouse models of genetic- and diet-induced obesity and diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.02.003openalex-snapshot
Fatty Acid Elongase 7 Catalyzes Lipidome Remodeling Essential for Human Cytomegalovirus Replication
inferred← citeshttps://doi.org/10.1016/j.clnu.2020.06.035openalex-snapshot
MiRNAs profile as biomarkers of nutritional therapy for the prevention of type 2 diabetes mellitus: From the CORDIOPREV study
inferred← citeshttps://doi.org/10.1016/j.coph.2009.07.003openalex-snapshot
Endoplasmic reticulum stress in β-cells and development of diabetes
inferred← citeshttps://doi.org/10.1016/j.diabet.2007.10.009openalex-snapshot
Postprandial fatty acid metabolism in the development of lipotoxicity and type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.ebiom.2015.03.012openalex-snapshot
Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes
inferred← citeshttps://doi.org/10.1016/j.ebiom.2020.103038openalex-snapshot
Glued in lipids: Lipointoxication in cystic fibrosis
inferred← citeshttps://doi.org/10.1016/j.ecl.2024.10.004openalex-snapshot
Treatment of Type 2 Diabetes in Patients with Obesity
inferred← citeshttps://doi.org/10.1016/j.ejphar.2012.09.023openalex-snapshot
A compound (DW1182v) protecting high glucose/palmitate-induced glucolipotoxicity to INS-1 beta cells preserves islet integrity and improves hyperglycemia in obese db/db mouse
inferred← citeshttps://doi.org/10.1016/j.ejphar.2014.09.047openalex-snapshot
Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway
inferred← citeshttps://doi.org/10.1016/j.ejphar.2016.03.023openalex-snapshot
Anti-diabetic effect of 3-hydroxy-2-naphthoic acid, an endoplasmic reticulum stress-reducing chemical chaperone
inferred← citeshttps://doi.org/10.1016/j.ejphar.2022.175221openalex-snapshot
Endoplasmic reticulum stress: A common pharmacologic target of cardioprotective drugs
inferred← citeshttps://doi.org/10.1016/j.ejphar.2024.177003openalex-snapshot
Asperuloside activates hepatic NRF2 signaling to stimulate mitochondrial metabolism and restore lipid homeostasis in high fat diet-induced MAFLD
inferred← citeshttps://doi.org/10.1016/j.fct.2018.12.022openalex-snapshot
Cellular toxicity of dietary trans fatty acids and its correlation with ceramide and diglyceride accumulation
inferred← citeshttps://doi.org/10.1016/j.febslet.2008.03.026openalex-snapshot
Oleanolic acid enhances insulin secretion in pancreatic β‐cells
inferred← citeshttps://doi.org/10.1016/j.febslet.2010.03.041openalex-snapshot
p24 family type 1 transmembrane proteins are required for insulin biosynthesis and secretion in pancreatic β‐cells
inferred← citeshttps://doi.org/10.1016/j.febslet.2014.04.030openalex-snapshot
Attenuation of unfolded protein response and apoptosis by mReg2 induced GRP78 in mouse insulinoma cells
inferred← citeshttps://doi.org/10.1016/j.foodchem.2012.10.088openalex-snapshot
Grape seed procyanidin extract modulates proliferation and apoptosis of pancreatic beta-cells
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2011.04.019openalex-snapshot
ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2014.04.011openalex-snapshot
(−)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.07.021openalex-snapshot
ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.11.010openalex-snapshot
(–)-Epicatechin in the control of glucose homeostasis: Involvement of redox-regulated mechanisms
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2020.11.023openalex-snapshot
Transient NADPH oxidase 2-dependent H2O2 production drives early palmitate-induced lipotoxicity in pancreatic islets
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e32804openalex-snapshot
Sustained feeding of a diet high in fat resulted in a decline in the liver's insulin-degrading enzyme levels in association with the induction of oxidative and endoplasmic reticulum stress in adult male rats: Evaluation of 4-phenylbutyric acid
inferred← citeshttps://doi.org/10.1016/j.ijcard.2014.03.176openalex-snapshot
PPARβ/δ attenuates palmitate-induced endoplasmic reticulum stress and induces autophagic markers in human cardiac cells
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.101368openalex-snapshot
GRP75 mediates endoplasmic reticulum–mitochondria coupling during palmitate-induced pancreatic β-cell apoptosis
inferred← citeshttps://doi.org/10.1016/j.jcjd.2016.02.001openalex-snapshot
The Herbal Medicine Cordyceps sinensis Protects Pancreatic Beta Cells from Streptozotocin-Induced Endoplasmic Reticulum Stress
inferred← citeshttps://doi.org/10.1016/j.jep.2020.112970openalex-snapshot
Costus pictus D. Don leaf extract stimulates GLP-1 secretion from GLUTag L-cells and has cytoprotective effects in BRIN-BD11 β-cells
inferred← citeshttps://doi.org/10.1016/j.jlr.2021.100095openalex-snapshot
PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions
inferred← citeshttps://doi.org/10.1016/j.jlr.2026.101036openalex-snapshot
Lipid desaturation and cellular viability: mechanisms, stem cell insights, and a desaturation window model
inferred← citeshttps://doi.org/10.1016/j.jmb.2019.09.016openalex-snapshot
Recent Insights Into Mechanisms of β-Cell Lipo- and Glucolipotoxicity in Type 2 Diabetes
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2014.03.007openalex-snapshot
Proanthocyanidins protect against early diabetic peripheral neuropathy by modulating endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2016.01.010openalex-snapshot
Docosahexaenoic acid and palmitic acid reciprocally modulate monocyte activation in part through endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.1016/j.lfs.2007.12.023openalex-snapshot
Comparison of the effect of individual saturated and unsaturated fatty acids on cell growth and death induction in the human pancreatic β-cell line NES2Y
inferred← citeshttps://doi.org/10.1016/j.lfs.2010.10.012openalex-snapshot
Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2 liver cells
inferred← citeshttps://doi.org/10.1016/j.lfs.2011.02.022openalex-snapshot
Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15
inferred← citeshttps://doi.org/10.1016/j.mce.2007.04.004openalex-snapshot
Involvement of Ca2+-mediated apoptotic signals in palmitate-induced MIN6N8a beta cell death
inferred← citeshttps://doi.org/10.1016/j.mce.2007.06.006openalex-snapshot
A busy cell—Endoplasmic reticulum stress in the pancreatic β-cell
inferred← citeshttps://doi.org/10.1016/j.mce.2008.12.005openalex-snapshot
Role of the transcriptional factor C/EBPβ in free fatty acid-elicited β-cell failure
inferred← citeshttps://doi.org/10.1016/j.mce.2009.09.031openalex-snapshot
Obesity and Type 2 diabetes: Slow down!—Can metabolic deceleration protect the islet beta cell from excess nutrient-induced damage?
inferred← citeshttps://doi.org/10.1016/j.mce.2011.09.013openalex-snapshot
Suppression of FoxO1/cell death-inducing DNA fragmentation factor α-like effector A (Cidea) axis protects mouse β-cells against palmitic acid-induced apoptosis
inferred← citeshttps://doi.org/10.1016/j.mce.2012.07.004openalex-snapshot
Repression of sterol regulatory element-binding protein 1-c is involved in the protective effects of exendin-4 in pancreatic β-cell line
inferred← citeshttps://doi.org/10.1016/j.mce.2013.12.002openalex-snapshot
Toxicity generated through inhibition of pyruvate carboxylase and carnitine palmitoyl transferase-1 is similar to high glucose/palmitate-induced glucolipotoxicity in INS-1 beta cells
inferred← citeshttps://doi.org/10.1016/j.mce.2015.03.007openalex-snapshot
Involvement of iron depletion in palmitate-induced lipotoxicity of beta cells
inferred← citeshttps://doi.org/10.1016/j.mce.2015.05.003openalex-snapshot
Fatty Acid-Binding Protein 4 mediates apoptosis via endoplasmic reticulum stress in mesangial cells of diabetic nephropathy
inferred← citeshttps://doi.org/10.1016/j.mce.2015.06.025openalex-snapshot
The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK
inferred← citeshttps://doi.org/10.1016/j.mce.2016.08.034openalex-snapshot
GLP-1 analogue recovers impaired insulin secretion from human islets treated with palmitate via down-regulation of SOCS2
inferred← citeshttps://doi.org/10.1016/j.metabol.2009.10.012openalex-snapshot
Palmitate induces insulin resistance without significant intracellular triglyceride accumulation in HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.metabol.2026.156607openalex-snapshot
Metformin suppresses β-cell apoptosis under ER stress by inhibiting protein translation
inferred← citeshttps://doi.org/10.1016/j.molmet.2015.01.003openalex-snapshot
Clic4, a novel protein that sensitizes β-cells to apoptosis
inferred← citeshttps://doi.org/10.1016/j.molmet.2017.07.017openalex-snapshot
Inhibition of cholinergic potentiation of insulin secretion from pancreatic islets by chronic elevation of glucose and fatty acids: Protection by casein kinase 2 inhibitor
inferred← citeshttps://doi.org/10.1016/j.molmet.2023.101773openalex-snapshot
HILPDA is a lipotoxic marker in adipocytes that mediates the autocrine negative feedback regulation of triglyceride hydrolysis by fatty acids and alleviates cellular lipotoxic stress
inferred← citeshttps://doi.org/10.1016/j.molmet.2023.101845openalex-snapshot
Independent activation of CREB3L2 by glucose fills a regulatory gap in mouse β-cells by co-ordinating insulin biosynthesis with secretory granule formation
inferred← citeshttps://doi.org/10.1016/j.molmet.2024.102082openalex-snapshot
Epigenetic suppression of creatine kinase B in adipocytes links endoplasmic reticulum stress to obesity-associated inflammation
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2010.11.035openalex-snapshot
Palmitate induces apoptosis in Schwann cells via both ceramide-dependent and independent pathways
inferred← citeshttps://doi.org/10.1016/j.numecd.2008.10.010openalex-snapshot
From chronic overnutrition to insulin resistance: The role of fat-storing capacity and inflammation
inferred← citeshttps://doi.org/10.1016/j.peptides.2009.11.011openalex-snapshot
Inhibition of Foxo1 mediates protective effects of ghrelin against lipotoxicity in MIN6 pancreatic β-cells
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2021.108033openalex-snapshot
Spexin: Its role, regulation, and therapeutic potential in the hypothalamus
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2024.108604openalex-snapshot
Protein-rich foods, sea foods, and gut microbiota amplify immune responses in chronic diseases and cancers – Targeting PERK as a novel therapeutic strategy for chronic inflammatory diseases, neurodegenerative disorders, and cancer
inferred← citeshttps://doi.org/10.1016/j.phrs.2019.104516openalex-snapshot
The role of MicroRNAs on endoplasmic reticulum stress in myocardial ischemia and cardiac hypertrophy
inferred← citeshttps://doi.org/10.1016/j.phrs.2025.107823openalex-snapshot
Targeting endoplasmic reticulum proteostasis in liver fibrosis: From signaling mechanisms to therapeutic opportunities
inferred← citeshttps://doi.org/10.1016/j.physbeh.2021.113312openalex-snapshot
The chemical chaperon 4-phenyl butyric acid restored high-fat diet- induced hippocampal insulin content and insulin receptor level reduction along with spatial learning and memory deficits in male rats
inferred← citeshttps://doi.org/10.1016/j.plefa.2010.02.018openalex-snapshot
Unsaturated fatty acids as cytoprotective agents in the pancreatic β-cell
inferred← citeshttps://doi.org/10.1016/j.plipres.2022.101198openalex-snapshot
Endoplasmic reticulum stress and lipids in health and diseases
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2017.08.001openalex-snapshot
Astrocytes and endoplasmic reticulum stress: A bridge between obesity and neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2026.107092openalex-snapshot
A comprehensive review on the mechanistics of free fatty acid-induced insulin resistance and it’s therapeutics: Molecular perspectives
inferred← citeshttps://doi.org/10.1016/j.redox.2022.102407openalex-snapshot
Integrated regulation of stress responses, autophagy and survival by altered intracellular iron stores
inferred← citeshttps://doi.org/10.1016/j.regpep.2009.12.017openalex-snapshot
Ghrelin inhibits cell apoptosis induced by lipotoxicity in pancreatic β-cell line
inferred← citeshttps://doi.org/10.1016/j.semcdb.2016.01.027openalex-snapshot
Mitochondria in human pluripotent stem cell apoptosis
inferred← citeshttps://doi.org/10.1016/j.tcb.2015.03.004openalex-snapshot
From zero to six double bonds: phospholipid unsaturation and organelle function
inferred← citeshttps://doi.org/10.1016/j.tem.2011.02.008openalex-snapshot
Endoplasmic reticulum stress and pancreatic β-cell death
inferred← citeshttps://doi.org/10.1016/j.tem.2014.02.003openalex-snapshot
Lipotoxic endoplasmic reticulum stress, β cell failure, and type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.tox.2025.154188openalex-snapshot
Antimony induces mitochondria-dependent and ER stress-triggered apoptosis via the oxidative stress-activated JNK signaling pathway in pancreatic islet β-cells
inferred← citeshttps://doi.org/10.1016/j.yexcr.2009.12.008openalex-snapshot
Synergistic effect of cAMP and palmitate in promoting altered mitochondrial function and cell death in HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.yexcr.2014.10.007openalex-snapshot
ATF6β regulates the Wfs1 gene and has a cell survival role in the ER stress response in pancreatic β-cells
inferred← citeshttps://doi.org/10.1016/j.yexcr.2015.09.022openalex-snapshot
Exocrine pancreas ER stress is differentially induced by different fatty acids
inferred← citeshttps://doi.org/10.1016/j.yexcr.2017.03.032openalex-snapshot
Palmitate mediated diacylglycerol accumulation causes endoplasmic reticulum stress, Plin2 degradation, and cell death in H9C2 cardiomyoblasts
inferred← citeshttps://doi.org/10.1016/j.yexcr.2019.04.031openalex-snapshot
PAQR3 regulates phosphorylation of FoxO1 in insulin-resistant HepG2 cells via NF-κB signaling pathway
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2014.10.002openalex-snapshot
Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/s1001-9294(11)60006-0openalex-snapshot
Regulation of Acyl-coenzyme A:Cholesterol Acyltransferase 2 Expression by Saturated Fatty Acids
inferred← citeshttps://doi.org/10.1016/s1875-5364(20)30054-6openalex-snapshot
Sangguayin preparation prevents palmitate-induced apoptosis by suppressing endoplasmic reticulum stress and autophagy in db/db mice and MIN6 pancreatic β-cells
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