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Sex-Specific Responses to Opiates: Animal and Human Studies

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cne.20962openalex-snapshot
Sex differences in the anatomical and functional organization of the periaqueductal gray‐rostral ventromedial medullary pathway in the rat: A potential circuit mediating the sexually dimorphic actions of morphine
inferredcites →https://doi.org/10.1002/cne.902250202openalex-snapshot
Demonstration of a sexual dimorphism in the distribution of serotonin‐immunoreactive fibers in the medial preoptic nucleus of the rat
inferredcites →https://doi.org/10.1002/cne.902760309openalex-snapshot
Distribution of opioid peptides in the preoptic region: Immunohistochemical evidence for a steroid‐sensitive enkephalin sexual dimorphism
inferredcites →https://doi.org/10.1007/bf00289259openalex-snapshot
The influence of gender on the frequency of pain and sedative medication administered to postoperative patients
inferredcites →https://doi.org/10.1007/bf01958921openalex-snapshot
Opioids and behavior: genetic aspects
inferredcites →https://doi.org/10.1007/bf01966467openalex-snapshot
Effects of pentazocine and acetylsalicylic acid on pain-rating, pain-related evoked potentials and vigilance in relationship to pharmakokinetic parameters
inferredcites →https://doi.org/10.1007/bf02245427openalex-snapshot
Endopeptidase 24.15 inhibition and opioid antinociception
inferredcites →https://doi.org/10.1007/bf03020523openalex-snapshot
Gender and pain upon movement are associated with the requirements for postoperative patient-controllediv analgesia: a prospective survey of 2,298 Chinese patients
inferredcites →https://doi.org/10.1007/s001010100206openalex-snapshot
[Postoperative pain therapy with hydromorphone and metamizole. A prospective randomized study in intravenous patient-controlled analgesia (PCA)].
inferredcites →https://doi.org/10.1007/s00213-001-0949-2openalex-snapshot
Sex and rat strain determine sensitivity to κ opioid-induced antinociception
inferredcites →https://doi.org/10.1007/s00213-002-1143-xopenalex-snapshot
Influence of gonadectomy on the antinociceptive effects of opioids in male and female rats
inferredcites →https://doi.org/10.1007/s002130000453openalex-snapshot
Sex-related differences in the antinociceptive effects of opioids: importance of rat genotype, nociceptive stimulus intensity, and efficacy at the µ opioid receptor
inferredcites →https://doi.org/10.1007/s002130050911openalex-snapshot
Sex differences in development of morphine tolerance and dependence in the rat
inferredcites →https://doi.org/10.1007/s002130100806openalex-snapshot
Early neonatal experience of Long-Evans rats results in long-lasting changes in morphine tolerance and dependence
inferredcites →https://doi.org/10.1007/s002130100821openalex-snapshot
Importance of sex and relative efficacy at the µ opioid receptor in the development of tolerance and cross-tolerance to the antinociceptive effects of opioids
inferredcites →https://doi.org/10.1016/0006-291x(82)92143-xopenalex-snapshot
Evidence contradicting the notion that gonadal hormones regulate brain opiate receptors
inferredcites →https://doi.org/10.1016/0006-8993(82)90758-2openalex-snapshot
Sex-related difference in the rat pituitary [Met5]-enkephalin level — altered by gonadectomy
inferredcites →https://doi.org/10.1016/0006-8993(85)91273-9openalex-snapshot
Analgesic, locomotor and lethal effects of morphine in the mouse: Strain comparisons
inferredcites →https://doi.org/10.1016/0006-8993(86)91261-8openalex-snapshot
Sexually dimorphic opioid distribution in the preoptic area: manipulation by gonadal steroids
inferredcites →https://doi.org/10.1016/0006-8993(90)90009-zopenalex-snapshot
Differential regulation of proenkephalin gene expression by estrogen in the ventromedial hypothalamus of male and female rats: implications for the molecular basis of a sexually differentiated behavior
inferredcites →https://doi.org/10.1016/0006-8993(90)90936-6openalex-snapshot
Developmental changes in opiate-induced analgesia in deer mice: sex and population differences
inferredcites →https://doi.org/10.1016/0006-8993(94)90366-2openalex-snapshot
μ-Opiate receptor binding is up-regulated in mice selectively bred for high stress-induced analgesia
inferredcites →https://doi.org/10.1016/0014-2999(82)90005-xopenalex-snapshot
Possible physiological role of adrenal and gonadal steroids in morphine analgesia
inferredcites →https://doi.org/10.1016/0014-2999(83)90319-9openalex-snapshot
Ovarian steroids and modulation of morphine-induced analgesia and catalepsy in female rats
inferredcites →https://doi.org/10.1016/0018-506x(91)90052-jopenalex-snapshot
Effects of estradiol and progesterone on the sensitivity to pain and on morphine-induced antinociception in female rats
inferredcites →https://doi.org/10.1016/0024-3205(83)90003-6openalex-snapshot
Testosterone does not influence opiate binding sites in the male rat brain
inferredcites →https://doi.org/10.1016/0024-3205(84)90633-7openalex-snapshot
Endocrine influences on the actions of morphine: IV. effects of sex and strain
inferredcites →https://doi.org/10.1016/0028-3908(84)90231-4openalex-snapshot
Monosodium glutamate and analgesia induced by morphineTest-specific effects
inferredcites →https://doi.org/10.1016/0028-3908(89)90197-4openalex-snapshot
Sex-related differences in the effects of morphine and stress on visceral pain
inferredcites →https://doi.org/10.1016/0031-9384(93)90042-eopenalex-snapshot
Interactions among aging, gender, and gonadectomy effects upon morphine antinociception in rats
inferredcites →https://doi.org/10.1016/0091-3057(87)90351-0openalex-snapshot
Sex and day-night differences in opiate-induced responses of insular wild deer mice, Peromyscus maniculatus triangularis
inferredcites →https://doi.org/10.1016/0091-3057(89)90363-8openalex-snapshot
Roles of gender, gonadectomy and estrous phase in the analgesic effects of intracerebroventricular morphine in rats
inferredcites →https://doi.org/10.1016/0091-3057(92)90015-8openalex-snapshot
Effect of adrenal and sex hormones on opioid analgesia and opioid receptor regulation
inferredcites →https://doi.org/10.1016/0091-3057(92)90075-qopenalex-snapshot
Roles of gender and gonadectomy in pilocarpine and clonidine analgesia in rats
inferredcites →https://doi.org/10.1016/0091-3057(93)90200-dopenalex-snapshot
Sex differences in the antinociceptive effects of the enkephalinase inhibitor, SCH 34826
inferredcites →https://doi.org/10.1016/0169-328x(89)90017-xopenalex-snapshot
Estrogen regulation of proenkephalin gene expression in the ventromedial hypothalamus of the rat: temporal qualities and synergism with progesterone
inferredcites →https://doi.org/10.1016/0196-9781(92)90038-5openalex-snapshot
Sex differences in the effects of Tyr-MIF-1 on morphine- and stress-induced analgesia
inferredcites →https://doi.org/10.1016/0196-9781(92)90096-lopenalex-snapshot
Sex differences in the effects of neuropeptide FF and IgG from neuropeptide FF on morphine- and stress-induced analgesia
inferredcites →https://doi.org/10.1016/0304-3940(96)12402-2openalex-snapshot
Gender difference in analgesic response to the kappa-opioid pentazocine
inferredcites →https://doi.org/10.1016/0304-3959(91)90168-wopenalex-snapshot
Gender effects and central opioid analgesia
inferredcites →https://doi.org/10.1016/0304-3959(95)00092-5openalex-snapshot
Estrogen and progesterone activate spinal kappa-opiate receptor analgesic mechanisms
inferredcites →https://doi.org/10.1016/0304-3959(95)00214-6openalex-snapshot
Gender variations in clinical pain experience
inferredcites →https://doi.org/10.1016/0306-4522(95)00335-gopenalex-snapshot
Enhancement of morphine analgesia by the GABAB agonist baclofen
inferredcites →https://doi.org/10.1016/0306-4522(96)00338-7openalex-snapshot
Orphanin FQ is a functional anti-opioid peptide
inferredcites →https://doi.org/10.1016/0361-9230(88)90032-9openalex-snapshot
Organismic variables and pain inhibition: Roles of gender and aging
inferredcites →https://doi.org/10.1016/0361-9230(90)90169-zopenalex-snapshot
Sex differences in the inhibitory effects of the NMDA antagonist, MK-801, on morphine and stress-induced analgesia
inferredcites →https://doi.org/10.1016/j.brainres.2004.03.056openalex-snapshot
Sex differences in systemic morphine analgesic tolerance following intrathecal morphine injections
inferredcites →https://doi.org/10.1016/j.ejphar.2004.01.012openalex-snapshot
Estrous cycle stage-dependent expression of acute tolerance to morphine analgesia in rats
inferredcites →https://doi.org/10.1016/j.ejphar.2006.02.020openalex-snapshot
Effects of memantine on estrogen-dependent acute tolerance to the morphine analgesia in female rats
inferredcites →https://doi.org/10.1016/j.ejphar.2006.10.010openalex-snapshot
Sex differences and role of gonadal hormones on glutamate level in the nucleus accumbens in morphine tolerant rats: A microdialysis study
inferredcites →https://doi.org/10.1016/j.jpain.2004.11.005openalex-snapshot
Morphine responses and experimental pain: Sex differences in side effects and cardiovascular responses but not analgesia
inferredcites →https://doi.org/10.1016/j.neuroscience.2006.08.034openalex-snapshot
Organizational and activational effects of testosterone on carrageenan-induced inflammatory pain and morphine analgesia
inferredcites →https://doi.org/10.1016/j.pain.2006.01.019openalex-snapshot
Influence of low doses of naltrexone on morphine antinociception and morphine tolerance in male and female rats of four strains
inferredcites →https://doi.org/10.1016/j.pbb.2003.12.020openalex-snapshot
Morphine tolerance in male and female rats
inferredcites →https://doi.org/10.1016/j.pbb.2005.02.003openalex-snapshot
NMDA antagonist modulation of morphine antinociception in female vs. male rats
inferredcites →https://doi.org/10.1016/j.pmn.2006.09.004openalex-snapshot
Pain Perception and Expression: The Influence of Gender, Personal Self-Efficacy, and Lifespan Socialization
inferredcites →https://doi.org/10.1016/s0006-8993(00)02685-8openalex-snapshot
A comparison of morphine analgesic tolerance in male and female mice
inferredcites →https://doi.org/10.1016/s0006-8993(00)03301-1openalex-snapshot
Morphine tolerance after chronic intracerebroventricular injection in male and female mice
inferredcites →https://doi.org/10.1016/s0006-8993(01)03350-9openalex-snapshot
Reversal of sex differences in morphine analgesia elicited from the ventrolateral periaqueductal gray in rats by neonatal hormone manipulations
inferredcites →https://doi.org/10.1016/s0006-8993(97)00569-6openalex-snapshot
Sex differences in N-methyl-d-aspartate involvement in κ opioid and non-opioid predator-induced analgesia in mice
inferredcites →https://doi.org/10.1016/s0006-8993(98)00353-9openalex-snapshot
Microinjection of morphine into the rostral ventromedial medulla produces greater antinociception in male compared to female rats
inferredcites →https://doi.org/10.1016/s0006-8993(98)00841-5openalex-snapshot
Sex differences in cocaine- and nicotine-induced antinociception in the rat
inferredcites →https://doi.org/10.1016/s0006-8993(98)01364-xopenalex-snapshot
Morphine antinociception elicited from the ventrolateral periaqueductal gray is sensitive to sex and gonadectomy differences in rats
inferredcites →https://doi.org/10.1016/s0009-9236(03)00152-8openalex-snapshot
Side effects of opioids during short-term administration: effect of age, gender, and race
inferredcites →https://doi.org/10.1016/s0014-2999(03)01782-5openalex-snapshot
Modification of morphine analgesia and tolerance by flumazenil in male and female rats
inferredcites →https://doi.org/10.1016/s0014-2999(97)01434-9openalex-snapshot
Characterization of neonatal rat morphine tolerance and dependence
inferredcites →https://doi.org/10.1016/s0022-3565(24)29556-2openalex-snapshot
Sex-Related Differences in Antinociception and Tolerance Development following Chronic Intravenous Infusion of Morphine in the Rat: Modulatory Role of Testosterone via Morphine Clearance
inferredcites →https://doi.org/10.1016/s0022-3565(24)36827-2openalex-snapshot
Sex Differences in Opioid Antinociception
inferredcites →https://doi.org/10.1016/s0022-3565(24)36831-4openalex-snapshot
Sex-Related Differences in Morphine’s Antinociceptive Activity: Relationship to Serum and Brain Morphine Concentrations
inferredcites →https://doi.org/10.1016/s0022-3565(24)38281-3openalex-snapshot
Sex Differences in Supraspinal Morphine Analgesia Are Dependent on Genotype
inferredcites →https://doi.org/10.1016/s0022-3565(25)21187-9openalex-snapshot
Gender-related differences in the antinociceptive properties of morphine.
inferredcites →https://doi.org/10.1016/s0022-3565(25)31528-4openalex-snapshot
Differential effects of leucine and methionine enkephalin on morphine-induced analgesia, acute tolerance and dependence.
inferredcites →https://doi.org/10.1016/s0022-3565(25)33466-xopenalex-snapshot
Endocrine influences on the actions of morphine. I. Alteration of target gland hormones.
inferredcites →https://doi.org/10.1016/s0165-6147(98)01279-6openalex-snapshot
Opioids: first lessons from knockout mice
inferredcites →https://doi.org/10.1016/s0169-328x(97)00194-0openalex-snapshot
Progesterone increases levels of μ-opioid receptor mRNA in the preoptic area and arcuate nucleus of ovariectomized, estradiol-treated female rats
inferredcites →https://doi.org/10.1016/s0196-9781(00)00252-7openalex-snapshot
Agonistic effects of the opioid buprenorphine on the nociceptin/OFQ receptor
inferredcites →https://doi.org/10.1016/s0304-3959(02)00457-8openalex-snapshot
Gonadal steroid hormone modulation of nociception, morphine antinociception and reproductive indices in male and female rats
inferredcites →https://doi.org/10.1016/s0304-3959(99)00119-0openalex-snapshot
The kappa opioid nalbuphine produces gender- and dose-dependent analgesia and antianalgesia in patients with postoperative pain
inferredcites →https://doi.org/10.1016/s0306-4522(01)00179-8openalex-snapshot
Orphanin FQ produces gender-specific modulation of trigeminal nociception: behavioral and electrophysiological observations
inferredcites →https://doi.org/10.1016/s0376-8716(00)00186-1openalex-snapshot
Morphine responses in humans: a retrospective analysis of sex differences
inferredcites →https://doi.org/10.1016/s1082-3174(99)70044-9openalex-snapshot
Does opioid analgesia show a gender preference for females?
inferredcites →https://doi.org/10.1016/s1082-3174(99)70045-0openalex-snapshot
Sex differences in opioid analgesia
inferredcites →https://doi.org/10.1016/s1550-8579(05)80042-7openalex-snapshot
Sex differences in pain perception
inferredcites →https://doi.org/10.1017/s0140525x97221485openalex-snapshot
Sex differences in pain
inferredcites →https://doi.org/10.1038/nm1196-1248openalex-snapshot
Kappa–opioids produce significantly greater analgesia in women than in men
inferredcites →https://doi.org/10.1046/j.1365-2702.1998.00192.xopenalex-snapshot
The prevalence and perception of pain amongst hospital in‐patients
inferredcites →https://doi.org/10.1073/pnas.0730053100openalex-snapshot
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans
inferredcites →https://doi.org/10.1073/pnas.93.7.3048openalex-snapshot
The genetics of pain and pain inhibition.
inferredcites →https://doi.org/10.1095/biolreprod32.3.501openalex-snapshot
Gonadal Steroid-Induced Modification of Opiate Binding Sites in Anterior Hypothalamus of Female Rats
inferredcites →https://doi.org/10.1097/00000539-199806000-00023openalex-snapshot
Experimental Pain in Healthy Human Subjects
inferredcites →https://doi.org/10.1097/00000542-199804000-00009openalex-snapshot
Sex-related Differences in the Influence of Morphine on Ventilatory Control in Humans
inferredcites →https://doi.org/10.1097/00000542-199905000-00017openalex-snapshot
Sex Differences in Morphine-induced Ventilatory Depression Reside within the Peripheral Chemoreflex Loop
inferredcites →https://doi.org/10.1097/00000542-200008000-00034openalex-snapshot
Gender Differences in Opioid-mediated Analgesia
inferredcites →https://doi.org/10.1097/00000542-200011000-00018openalex-snapshot
Sex Differences in Morphine Analgesia
inferredcites →https://doi.org/10.1097/00000542-200301000-00011openalex-snapshot
Difference in Risk Factors for Postoperative Nausea and Vomiting
inferredcites →https://doi.org/10.1097/00000542-200401000-00021openalex-snapshot
Pharmacokinetic-Pharmacodynamic Modeling of Morphine-6-glucuronide-induced Analgesia in Healthy Volunteers
inferredcites →https://doi.org/10.1097/00000542-200507000-00020openalex-snapshot
Alfentanil and Placebo Analgesia
inferredcites →https://doi.org/10.1097/00000542-200507000-00023openalex-snapshot
Sex- and Age-related Differences in Morphine Requirements for Postoperative Pain Relief
inferredcites →https://doi.org/10.1097/00001756-199609020-00012openalex-snapshot
Orphanin FQ acts as a supraspinal, but not a spinal, anti-opioid peptide
inferredcites →https://doi.org/10.1097/00005650-198106000-00004openalex-snapshot
Physicians?? Attitudes Toward Female Patients
inferredcites →https://doi.org/10.1097/00006565-199602000-00009openalex-snapshot
Conscious sedation for pediatric orthopaedic emergencies
inferredcites →https://doi.org/10.1097/00132586-199908000-00058openalex-snapshot
Experimental Pain in Healthy Human Subjects: Gender Differences in Nociception and in Response to Ibuprofen
inferredcites →https://doi.org/10.1111/j.1440-1681.1995.tb02012.xopenalex-snapshot
SEX DIFFERENCES AND THE EFFECT OF GONADECTOMY ON MORPHINE‐INDUCED ANTINOCICEPTION AND DEPENDENCE IN RATS AND MICE
inferredcites →https://doi.org/10.1124/jpet.107.123620openalex-snapshot
Sexually Dimorphic Recruitment of Spinal Opioid Analgesic Pathways by the Spinal Application of Morphine
inferredcites →https://doi.org/10.1124/jpet.300.2.695openalex-snapshot
Role of Steroids in Sex Differences in Morphine-Induced Analgesia: Activational and Organizational Effects
inferredcites →https://doi.org/10.1136/bmj.322.7288.710openalex-snapshot
Sex differences in speed of emergence and quality of recovery after anaesthesia: cohort study
inferredcites →https://doi.org/10.1136/jmg.2004.027698openalex-snapshot
Melanocortin-1 receptor gene variants affect pain and μ-opioid analgesia in mice and humans
inferredcites →https://doi.org/10.1146/annurev.ne.07.030184.001521openalex-snapshot
Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry
inferredcites →https://doi.org/10.1152/ajpregu.00831.2005openalex-snapshot
NMDA receptor antagonism disrupts the development of morphine analgesic tolerance in male, but not female C57BL/6J mice
inferredcites →https://doi.org/10.1159/000124154openalex-snapshot
Castration Affects Male Rat Brain Opiate Receptor Content
inferredcites →https://doi.org/10.1159/000125040openalex-snapshot
Alterations in Brain Opiate Receptor Mechanisms on Proestrous Afternoon
inferredcites →https://doi.org/10.1210/endo-119-5-2297openalex-snapshot
Response of Rat Pituitary Anterior Lobe Prodynorphin Products to Changes in Gonadal Steroid Environment*
inferredcites →https://doi.org/10.1210/endo-126-2-804openalex-snapshot
Estrogen and Progesterone Regulate Opiate Receptor Densities in Multiple Brain Regions*
inferredcites →https://doi.org/10.1213/01.ane.0000080153.36643.83openalex-snapshot
Women Experience More Pain and Require More Morphine Than Men to Achieve a Similar Degree of Analgesia
inferredcites →https://doi.org/10.1523/jneurosci.4783-06.2006openalex-snapshot
Activation of Opioid Receptor Like-1 Receptor in the Spinal Cord Produces Sex-Specific Antinociception in the Rat: Estrogen Attenuates Antinociception in the Female, whereas Testosterone Is Required for the Expression of Antinociception in the Male
inferredcites →https://doi.org/10.1592/phco.24.17.1675.52335openalex-snapshot
Analgesic and Hemodynamic Effects of a Single 7.5‐mg Intravenous Dose of Morphine in Patients with Moderate‐to‐Severe Postoperative Pain
inferredcites →https://doi.org/10.3727/107156995819563492openalex-snapshot
MU OPIOID RECEPTOR (MOR-1) mRNA LEVELS ARE ALTERED IN MICE WITH DIFFERENTIAL ANALGESIC SENSITIVITY TO THE MU AGONIST DAMGO

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4133352openalex-extracted
Sex Differences in the Impact of Pain, Morphine Administration and Morphine Withdrawal on Quality of Life in Rats
inferred← citeshttps://doi.org/10.1002/9780470921920.edm004openalex-snapshot
Sex Differences in Drug Metabolism
inferred← citeshttps://doi.org/10.1002/cphy.c100061openalex-snapshot
Effects of Anesthetics, Sedatives, and Opioids on Ventilatory Control
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2012.tb00463.xopenalex-snapshot
Effects of Anesthetics, Sedatives, and Opioids on Ventilatory Control
inferred← citeshttps://doi.org/10.1002/jnr.25103openalex-snapshot
Sex differences in morphine sensitivity are associated with differential glial expression in the brainstem of rats with neuropathic pain
inferred← citeshttps://doi.org/10.1002/npr2.70148openalex-snapshot
The rs10781468 Genetic Polymorphism of the Gαq ( GNAQ ) Gene Is Associated With Responsiveness to Opioid Analgesics in Patients With Postoperative and Cancer Pain: An Exploratory Study
inferred← citeshttps://doi.org/10.1007/164_2019_282openalex-snapshot
Genetic Background and Sex: Impact on Generalizability of Research Findings in Pharmacology Studies
inferred← citeshttps://doi.org/10.1007/978-3-319-12108-6_11openalex-snapshot
Hormonal Regulation of Liver Cytochrome P450 Enzymes
inferred← citeshttps://doi.org/10.1007/s00213-013-3129-2openalex-snapshot
Pharmacological traits of delta opioid receptors: pitfalls or opportunities?
inferred← citeshttps://doi.org/10.1007/s00213-014-3784-yopenalex-snapshot
Sex differences in the effects of adolescent social deprivation on alcohol consumption in μ-opioid receptor knockout mice
inferred← citeshttps://doi.org/10.1007/s00540-025-03581-zopenalex-snapshot
Opioid ceiling in non-cancer pain: a 90-MME hard stop may overlook sex-specific pharmacokinetics
inferred← citeshttps://doi.org/10.1016/b978-0-12-802388-4.00003-3openalex-snapshot
Sex Differences in Neuroanatomy and Neurophysiology
inferred← citeshttps://doi.org/10.1016/b978-0-323-05541-3.00026-0openalex-snapshot
Anesthesia for Cesarean Delivery
inferred← citeshttps://doi.org/10.1016/j.arr.2014.03.001openalex-snapshot
Geriatric dyspnea: Doing worse, feeling better
inferred← citeshttps://doi.org/10.1016/j.bbr.2018.01.031openalex-snapshot
Morphine antinociception on thermal sensitivity and place conditioning in male and female rats treated with intraplantar complete freund’s adjuvant
inferred← citeshttps://doi.org/10.1016/j.brainres.2010.09.040openalex-snapshot
The effects of acupuncture on the brain networks for emotion and cognition: An observation of gender differences
inferred← citeshttps://doi.org/10.1016/j.brainres.2017.01.011openalex-snapshot
Dissociation of morphine analgesic effects in the sensory and affective components of formalin-induced spontaneous pain in male and female rats
inferred← citeshttps://doi.org/10.1016/j.drugalcdep.2009.10.012openalex-snapshot
Psychopharmacological effects of oxycodone in healthy volunteers: Roles of alcohol-drinking status and sex
inferred← citeshttps://doi.org/10.1016/j.drugalcdep.2009.11.019openalex-snapshot
Obstructive sleep apnea is more common than central sleep apnea in methadone maintenance patients with subjective sleep complaints
inferred← citeshttps://doi.org/10.1016/j.ejcts.2009.09.041openalex-snapshot
Influence of gender on quality of life after lung surgery☆
inferred← citeshttps://doi.org/10.1016/j.ijcard.2014.11.019openalex-snapshot
Need for gender-specific pre-analytical testing: The dark side of the moon in laboratory testing
inferred← citeshttps://doi.org/10.1016/j.jcma.2013.05.003openalex-snapshot
An investigation on influential factors of patient-controlled epidural analgesic requirement over time for upper abdominal surgeries
inferred← citeshttps://doi.org/10.1016/j.jocn.2020.04.030openalex-snapshot
Gender differences in use of prolonged non-operative therapies prior to index ACDF surgery
inferred← citeshttps://doi.org/10.1016/j.jopan.2010.05.005openalex-snapshot
Opioids
inferred← citeshttps://doi.org/10.1016/j.jpain.2010.01.270openalex-snapshot
A Multicenter, Randomized, Double-Blind, Controlled Dose Finding Study of NGX-4010, a High-Concentration Capsaicin Patch, for the Treatment of Postherpetic Neuralgia
inferred← citeshttps://doi.org/10.1016/j.lfs.2010.10.007openalex-snapshot
Sex differences in kappa opioid pharmacology
inferred← citeshttps://doi.org/10.1016/j.molpha.2026.100112openalex-snapshot
Differential impacts of exon 1–associated and exon 11–associated variants of the rat mu opioid receptor gene, Oprm1, on buprenorphine- and morphine-induced analgesia and respiratory depression in male rats
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2022.104522openalex-snapshot
Sex differences in opioid receptor mediated effects: Role of androgens
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2022.104992openalex-snapshot
Placentophagia and the Tao of POEF
inferred← citeshttps://doi.org/10.1016/j.neulet.2009.10.016openalex-snapshot
Testosterone is essential for α2-adrenoceptor-induced antinociception in the trigeminal region of the male rat
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2012.04.028openalex-snapshot
Sex differences in the Nociceptin/Orphanin FQ system in rat spinal cord following chronic morphine treatment
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2025.110563openalex-snapshot
Pharmacological and pharmacokinetic study of Isobutyryfentanyl in female and male CD1 Mice
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2010.08.016openalex-snapshot
Altered morphine-induced analgesia in neurotensin type 1 receptor null mice
inferred← citeshttps://doi.org/10.1016/j.pain.2010.06.012openalex-snapshot
Do sex differences exist in opioid analgesia? A systematic review and meta-analysis of human experimental and clinical studies
inferred← citeshttps://doi.org/10.1016/j.pain.2010.09.018openalex-snapshot
Sex-specificity and estrogen-dependence of kappa opioid receptor-mediated antinociception and antihyperalgesia
inferred← citeshttps://doi.org/10.1016/j.pain.2010.11.033openalex-snapshot
Evaluation of menstrual cycle effects on morphine and pentazocine analgesia
inferred← citeshttps://doi.org/10.1016/j.pain.2014.05.032openalex-snapshot
TAOK3 , a novel genome-wide association study locus associated with morphine requirement and postoperative pain in a retrospective pediatric day surgery population
inferred← citeshttps://doi.org/10.1016/j.pbb.2008.09.015openalex-snapshot
Study of morphine-induced dependence in gonadectomized male and female mice
inferred← citeshttps://doi.org/10.1016/j.pbb.2016.06.006openalex-snapshot
Sex differences in responsiveness to the prescription opioid oxycodone in mice
inferred← citeshttps://doi.org/10.1016/j.physbeh.2021.113630openalex-snapshot
Fentanyl-induced acute and conditioned behaviors in two inbred mouse lines: Potential role for Glyoxalase
inferred← citeshttps://doi.org/10.1016/j.pmn.2010.11.005openalex-snapshot
Women’s Pain Management Issues
inferred← citeshttps://doi.org/10.1016/j.psyneuen.2009.08.008openalex-snapshot
Sex differences in the self-administration of cannabinoids and other drugs of abuse
inferred← citeshttps://doi.org/10.1016/j.resp.2015.06.003openalex-snapshot
Inhaled carbon dioxide causes dose-dependent paradoxical bradypnea in animals anesthetized with pentobarbital, but not with isoflurane or ketamine
inferred← citeshttps://doi.org/10.1016/j.resp.2024.104300openalex-snapshot
Cardiorespiratory failure induced by inhalation of aerosolized fentanyl in anesthetized rats
inferred← citeshttps://doi.org/10.1016/j.sjpain.2012.02.001openalex-snapshot
Epidural pain management after open lateral thoracotomy: Female patients have better pain relief and need smaller amounts of analgesics than males
inferred← citeshttps://doi.org/10.1016/j.taap.2025.117550openalex-snapshot
Cardiorespiratory failure and sudden death induced by carfentanil exposure: Involvement of central mu1 opioid receptors
inferred← citeshttps://doi.org/10.1016/j.wneu.2018.08.131openalex-snapshot
Gender Differences in Use of Prolonged Nonoperative Therapies Before Index Lumbar Surgery
inferred← citeshttps://doi.org/10.1016/j.yfrne.2012.09.004openalex-snapshot
Importance of sex to pain and its amelioration; relevance of spinal estrogens and its membrane receptors
inferred← citeshttps://doi.org/10.1016/j.yfrne.2014.04.003openalex-snapshot
Sex differences in addictive disorders
inferred← citeshttps://doi.org/10.1016/j.yfrne.2019.100766openalex-snapshot
Effects of opioids on the parental brain in health and disease
inferred← citeshttps://doi.org/10.1016/j.yhbeh.2018.04.009openalex-snapshot
Effects of opioid- and non-opioid analgesics on responses to psychosocial stress in humans
inferred← citeshttps://doi.org/10.1016/s0034-7094(11)70091-5openalex-snapshot
Sex and Pain Perception and Analgesia
inferred← citeshttps://doi.org/10.1017/9781316443217.004openalex-snapshot
Covariate Analysis in Clinical Anaesthesia
inferred← citeshttps://doi.org/10.1021/acschemneuro.2c00779openalex-snapshot
Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model
inferred← citeshttps://doi.org/10.1021/acsptsci.0c00066openalex-snapshot
Abuse Liability, Anti-Nociceptive, and Discriminative Stimulus Properties of IBNtxA
inferred← citeshttps://doi.org/10.1038/npp.2013.193openalex-snapshot
Obesity at Conception Programs the Opioid System in the Offspring Brain
inferred← citeshttps://doi.org/10.1038/nrn3360openalex-snapshot
Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon
inferred← citeshttps://doi.org/10.1038/s41386-023-01711-3openalex-snapshot
Delayed estrogen actions diminish food consumption without changing food approach, motor activity, or hypothalamic activation elicited by corticostriatal µ-opioid signaling
inferred← citeshttps://doi.org/10.1038/s41598-020-76934-1openalex-snapshot
Experimental sleep disruption attenuates morphine analgesia: findings from a randomized trial and implications for the opioid abuse epidemic
inferred← citeshttps://doi.org/10.1038/srep34493openalex-snapshot
Electroacupuncture in conscious free-moving mice reduces pain by ameliorating peripheral and central nociceptive mechanisms
inferred← citeshttps://doi.org/10.1038/tpj.2013.30openalex-snapshot
Genetic variation in OPRD1 and the response to treatment for opioid dependence with buprenorphine in European-American females
inferred← citeshttps://doi.org/10.1080/00207454.2019.1709841openalex-snapshot
Long-time effects of prenatal morphine, tramadol, methadone, and buprenorphine exposure on seizure and anxiety in immature rats
inferred← citeshttps://doi.org/10.1080/22201173.2009.10872580openalex-snapshot
Gender and pain—is it an issue?
inferred← citeshttps://doi.org/10.1093/acprof:oso/9780195373035.003.0028openalex-snapshot
8.3 Imaging Dopamine’s Role in Drug Abuse and Addiction
inferred← citeshttps://doi.org/10.1093/bja/aeq089openalex-snapshot
Assessment of nociceptin/orphanin FQ and μ-opioid receptor mRNA in the human right atrium
inferred← citeshttps://doi.org/10.1095/biolreprod.115.128686openalex-snapshot
Systemic Morphine Treatment Derails Normal Uterine Receptivity, Leading to Embryo Implantation Failure in Mice1
inferred← citeshttps://doi.org/10.1097/01.mjt.0000433939.84373.2dopenalex-snapshot
A Randomized Comparison of Remifentanil Target-Controlled Infusion Versus Dexmedetomidine Single-Dose Administration
inferred← citeshttps://doi.org/10.1097/01.orn.0000406638.19178.07openalex-snapshot
New thinking about postoperative pain management
inferred← citeshttps://doi.org/10.1097/aco.0b013e32831a4074openalex-snapshot
Update on the role of paravertebral blocks for thoracic surgery: are they worth it?
inferred← citeshttps://doi.org/10.1097/aln.0b013e31818db88copenalex-snapshot
Phase 2, Double-blind, Placebo-controlled, Dose-Response Trial of Intravenous Adenosine for Perioperative Analgesia
inferred← citeshttps://doi.org/10.1097/ana.0000000000000094openalex-snapshot
Determination of EC95 of Remifentanil for Smooth Emergence From Propofol Anesthesia in Patients Undergoing Transsphenoidal Surgery
inferred← citeshttps://doi.org/10.1097/bsd.0000000000000761openalex-snapshot
Sex-specific and Age-specific Analgesia for Early Postoperative Pain Management After Lumbar Decompressive Surgery
inferred← citeshttps://doi.org/10.1097/j.pain.0000000000001420openalex-snapshot
Increased pain sensitivity and decreased opioid analgesia in T-cell-deficient mice and implications for sex differences
inferred← citeshttps://doi.org/10.1097/md.0000000000003878openalex-snapshot
Optimal effect-site concentration of remifentanil for preventing cough during removal of the double-lumen endotracheal tube from sevoflurane-remifentanil anesthesia
inferred← citeshttps://doi.org/10.1097/md.0000000000005032openalex-snapshot
Effect of sex differences in remifentanil requirements for the insertion of a laryngeal mask airway during propofol anesthesia
inferred← citeshttps://doi.org/10.1097/md.0000000000011258openalex-snapshot
Predicting effective remifentanil concentration in 95% of patients to prevent emergence cough after laryngomicroscopic surgery
inferred← citeshttps://doi.org/10.1097/pcc.0b013e318253c80eopenalex-snapshot
Opioid Analgesia in Mechanically Ventilated Children
inferred← citeshttps://doi.org/10.1111/acem.12529openalex-snapshot
Gender Differences in Acute and Chronic Pain in the Emergency Department: Results of the 2014Academic Emergency MedicineConsensus Conference Pain Section
inferred← citeshttps://doi.org/10.1111/acer.13898openalex-snapshot
Exploring Sex Differences in the Attenuation of Ethanol Drinking by Naltrexone in Dependent Rats During Early and Protracted Abstinence
inferred← citeshttps://doi.org/10.1111/bcpt.12069openalex-snapshot
Spinal RhoA/Rho Kinase Signalling Pathway may Participate in the Development of Bone Cancer Pain
inferred← citeshttps://doi.org/10.1111/bcpt.13330openalex-snapshot
Population pharmacokinetic‐pharmacodynamic modelling of liquid and controlled‐release formulations of oxycodone in healthy volunteers
inferred← citeshttps://doi.org/10.1111/bcpt.13634openalex-snapshot
Effect of Roux‐en‐Y gastric bypass on the pharmacokinetic‐pharmacodynamic relationships of liquid and controlled‐release formulations of oxycodone
inferred← citeshttps://doi.org/10.1111/bph.12645openalex-snapshot
Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain
inferred← citeshttps://doi.org/10.1111/bph.12728openalex-snapshot
Modulation of imidazoline I 2binding sites by CR 4056 relieves postoperative hyperalgesia in male and female rats
inferred← citeshttps://doi.org/10.1111/j.1365-2044.2008.05760.xopenalex-snapshot
Association between human opioid receptor genes polymorphisms and pressure pain sensitivity in females*
inferred← citeshttps://doi.org/10.1111/j.1365-2885.2010.01264.xopenalex-snapshot
The influence of modulation of P‐glycoprotein and /or Cytochrome P450 3A on the pharmacokinetics and pharmacodynamics of orally administered morphine in dogs
inferred← citeshttps://doi.org/10.1111/j.1399-6576.2011.02620.xopenalex-snapshot
Smooth emergence in men undergoing nasal surgery: the effect site concentration of remifentanil for preventing cough after sevoflurane‐balanced anaesthesia
inferred← citeshttps://doi.org/10.1111/j.1460-9592.2010.03515.xopenalex-snapshot
Pain management in 100 episodes of severe mucositis in children
inferred← citeshttps://doi.org/10.1111/j.1526-4637.2010.01004.xopenalex-snapshot
A Multicenter, Randomized, Double-Blind, Controlled Study of NGX-4010, a High-Concentration Capsaicin Patch, for the Treatment of Postherpetic Neuralgia
inferred← citeshttps://doi.org/10.1111/j.1526-4637.2012.01467.xopenalex-snapshot
Medical and Psychological Risks and Consequences of Long-Term Opioid Therapy in Women
inferred← citeshttps://doi.org/10.1111/j.1533-2500.2010.00414.xopenalex-snapshot
Fentanyl Buccal Tablet for Breakthrough Cancer Pain: Why Titrate?
inferred← citeshttps://doi.org/10.1111/jnc.15798openalex-snapshot
Improving neuropathic pain treatment – by rigorous stratification from bench to bedside
inferred← citeshttps://doi.org/10.1124/dmd.122.000915openalex-snapshot
Sexual Dimorphism in the Expression of Cytochrome P450 Enzymes in Rat Heart, Liver, Kidney, Lung, Brain, and Small Intestine
inferred← citeshttps://doi.org/10.1124/jpet.111.183905openalex-snapshot
Sex Difference in κ-Opioid Receptor (KOPR)-Mediated Behaviors, Brain Region KOPR Level and KOPR-Mediated Guanosine 5′-O-(3-[35S]Thiotriphosphate) Binding in the Guinea Pig
inferred← citeshttps://doi.org/10.1124/mol.120.119552openalex-snapshot
Spinal Opioid Tolerance Depends upon Platelet-Derived Growth Factor Receptor-β Signaling, Not μ-Opioid Receptor Internalization
inferred← citeshttps://doi.org/10.1152/japplphysiol.00116.2026openalex-snapshot
Partially countering the physiological effects of fentanyl with naloxone or d -cysteine ethyl ester in adult goats
inferred← citeshttps://doi.org/10.1155/2009/462879openalex-snapshot
The Role of the Periaqueductal Gray in the Modulation of Pain in Males and Females: Are the Anatomy and Physiology Really that Different?
inferred← citeshttps://doi.org/10.11606/t.5.2010.tde-22092010-112609openalex-snapshot
O impacto neuroendocrinológico do uso prolongado de morfina por vias espinal e oral no tratamento da dor crônica
inferred← citeshttps://doi.org/10.1161/jaha.122.029081openalex-snapshot
Plasma Pro‐Enkephalin A and Incident Cognitive Impairment: The Reasons for Geographic and Racial Differences in Stroke Cohort
inferred← citeshttps://doi.org/10.1177/1099800411419493openalex-snapshot
Sex Differences in Pain Responses at Maturity Following Neonatal Repeated Minor Pain Exposure in Rats
inferred← citeshttps://doi.org/10.1177/15593258221092367openalex-snapshot
A Response Surface Analysis of the Combination of Dexmedetomidine and Sufentanil for Attenuating the Haemodynamic Response to Endotracheal Intubation
inferred← citeshttps://doi.org/10.1186/1744-8069-9-45openalex-snapshot
Sex Differences in Opioid Analgesia and Addiction: Interactions among Opioid Receptors and Estrogen Receptors
inferred← citeshttps://doi.org/10.1186/2042-6410-3-26openalex-snapshot
Neural and psychosocial contributions to sex differences in knee osteoarthritic pain
inferred← citeshttps://doi.org/10.1186/s12871-020-0951-zopenalex-snapshot
Effect of sex differences in remifentanil requirements for inhibiting the response to a CO2 pneumoperitoneum during propofol anesthesia: an up-and-down sequential allocation trial
inferred← citeshttps://doi.org/10.1213/ane.0000000000002016openalex-snapshot
Factors Influencing Quality of Pain Management in a Physician Staffed Helicopter Emergency Medical Service
inferred← citeshttps://doi.org/10.1213/ane.0b013e3181788cb6openalex-snapshot
Sex and Gender in the Perioperative Period: Wake Up to Reality
inferred← citeshttps://doi.org/10.1213/ane.0b013e31822c9a44openalex-snapshot
The Optimal Dose of Prophylactic Intravenous Naloxone in Ameliorating Opioid-Induced Side Effects in Children Receiving Intravenous Patient-Controlled Analgesia Morphine for Moderate to Severe Pain
inferred← citeshttps://doi.org/10.12703/p7-56openalex-snapshot
The search for novel analgesics: targets and mechanisms
inferred← citeshttps://doi.org/10.1371/journal.pone.0218074openalex-snapshot
Effect-site concentration of remifentanil for smooth emergence from sevoflurane anesthesia in patients undergoing endovascular neurointervention
inferred← citeshttps://doi.org/10.1590/s0034-70942011000600014openalex-snapshot
Sexo e percepção da dor e analgesia
inferred← citeshttps://doi.org/10.1590/s1806-00132011000200016openalex-snapshot
Opioides, sexo e gênero
inferred← citeshttps://doi.org/10.21203/rs.3.rs-5949417/v1openalex-snapshot
Effect of sex differences on the median effective dose of remimazolam combined with remifentanil in gastroscopy: an up-and-down sequential allocation trial
inferred← citeshttps://doi.org/10.2147/cia.s151476openalex-snapshot
Sex-related differences in effect-site concentration of remifentanil for preventing anesthetic emergence cough in elderly patients
inferred← citeshttps://doi.org/10.22159/ajpcr.2018.v11i8.26624openalex-snapshot
INFLUENCE OF GENDER AND OBESITY ON ANALGESIC MODULATION OF TRAMADOL IN RATS
inferred← citeshttps://doi.org/10.2217/17455057.5.1.79openalex-snapshot
Gender Differences and Pain Medication
inferred← citeshttps://doi.org/10.2217/17455057.5.2.205openalex-snapshot
Pharmacologic Management of the Older Woman Undergoing Surgery
inferred← citeshttps://doi.org/10.2217/pgs.12.152openalex-snapshot
Pharmacogenomics of Opioids and Perioperative Pain Management
inferred← citeshttps://doi.org/10.22541/au.160167496.62768848openalex-snapshot
Sex Differences in Opioid-Mediated Effects: Role of Androgens
inferred← citeshttps://doi.org/10.25267/commons.2013.v2.i1.07openalex-snapshot
Women's Pain
inferred← citeshttps://doi.org/10.29252/jarums.18.1.70openalex-snapshot
Effects of Testosterone on Analgesia in Formalin-Treated Mice
inferred← citeshttps://doi.org/10.30802/aalas-cm-19-000066openalex-snapshot
A Review of Strain and Sex Differences in Response to Pain and Analgesia in Mice
inferred← citeshttps://doi.org/10.3103/s0096392514030055openalex-snapshot
Behavioral effect of soymorphin-5-amide in rats
inferred← citeshttps://doi.org/10.3349/ymj.2014.55.3.807openalex-snapshot
Sex Differences in Remifentanil Requirements for Preventing Cough during Anesthetic Emergence
inferred← citeshttps://doi.org/10.3389/fnbeh.2020.00074openalex-snapshot
Sex Differences and the Role of Estradiol in Mesolimbic Reward Circuits and Vulnerability to Cocaine and Opiate Addiction
inferred← citeshttps://doi.org/10.3389/fpsyt.2015.00024openalex-snapshot
Importance of Sex Differences in Impulse Control and Addictions
inferred← citeshttps://doi.org/10.3389/fpsyt.2015.00175openalex-snapshot
Sex Differences in Behavioral Dyscontrol: Role in Drug Addiction and Novel Treatments
inferred← citeshttps://doi.org/10.3390/biomedicines11092460openalex-snapshot
Gender-Specific Interactions in a Visual Object Recognition Task in Persons with Opioid Use Disorder
inferred← citeshttps://doi.org/10.3390/jcm13195682openalex-snapshot
Assessing Gender Differences in Neuropathic Pain Management: Findings from a Real-Life Clinical Cross-Sectional Observational Study
inferred← citeshttps://doi.org/10.3390/jpm12060907openalex-snapshot
Sex-Related Differences in Pharmacological Response to CNS Drugs: A Narrative Review
inferred← citeshttps://doi.org/10.3904/kjim.2016.044openalex-snapshot
Initial titration with 200 μg fentanyl buccal tablets: a retrospective safety analysis in Korean cancer patients
inferred← citeshttps://doi.org/10.3906/sag-1701-113openalex-snapshot
Sex-related differences in the efficacy of dexamethasone pretreatmentfor postoperative analgesia in patients undergoing laparoscopiccholecystectomy: a randomized controlled study
inferred← citeshttps://doi.org/10.4097/kjae.2010.58.3.244openalex-snapshot
The influence of age and gender on remifentanil EC50for preventing rocuronium induced withdrawal movements
inferred← citeshttps://doi.org/10.70675/3e455976zb236z4f29zb2e9z85216103c7ddopenalex-snapshot
Apport de l'imagerie par tomographie d'émission de positons pour l'étude de la variabilité de réponse aux opioïdes
inferred← citeshttps://doi.org/10.82308/12349openalex-snapshot
Social modulation and communication of pain in the laboratory mouse
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