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Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ajmg.a.20426openalex-snapshot
Association of chromosomal regions 3p21.2, 10p13, and 16p13.3 with nonsyndromic cleft lip and palate
inferredcites →https://doi.org/10.1002/dvdy.10466openalex-snapshot
Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome
inferredcites →https://doi.org/10.1002/dvdy.21534openalex-snapshot
Mice with an anterior cleft of the palate survive neonatal lethality
inferredcites →https://doi.org/10.1006/dbio.1998.8994openalex-snapshot
FGF-10 Is a Chemotactic Factor for Distal Epithelial Buds during Lung Development
inferredcites →https://doi.org/10.1006/dbio.1999.9317openalex-snapshot
Cell Migration and Chick Limb Development: Chemotactic Action of FGF-4 and the AER
inferredcites →https://doi.org/10.1006/dbio.2000.9644openalex-snapshot
Medial Edge Epithelial Cell Fate during Palatal Fusion
inferredcites →https://doi.org/10.1006/dbio.2002.0729openalex-snapshot
Wnt5a Participates in Distal Lung Morphogenesis
inferredcites →https://doi.org/10.1016/j.cell.2004.09.019openalex-snapshot
Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth
inferredcites →https://doi.org/10.1016/j.devcel.2005.05.016openalex-snapshot
Wnt9b Plays a Central Role in the Regulation of Mesenchymal to Epithelial Transitions Underlying Organogenesis of the Mammalian Urogenital System
inferredcites →https://doi.org/10.1016/j.devcel.2007.02.016openalex-snapshot
Wnt-5A/Ror2 Regulate Expression of XPAPC through an Alternative Noncanonical Signaling Pathway
inferredcites →https://doi.org/10.1016/j.ydbio.2004.09.010openalex-snapshot
The cellular and molecular etiology of the cleft secondary palate in Fgf10 mutant mice
inferredcites →https://doi.org/10.1016/j.ydbio.2005.08.035openalex-snapshot
Wnt5a regulates Shh and Fgf10 signaling during lung development
inferredcites →https://doi.org/10.1016/j.ydbio.2006.02.017openalex-snapshot
Medaka unextended-fin mutants suggest a role for Hoxb8a in cell migration and osteoblast differentiation during appendage formation
inferredcites →https://doi.org/10.1016/j.ydbio.2006.07.042openalex-snapshot
Molecular control of secondary palate development
inferredcites →https://doi.org/10.1016/j.yexcr.2007.03.013openalex-snapshot
Cortactin involvement in the keratinocyte growth factor and fibroblast growth factor 10 promotion of migration and cortical actin assembly in human keratinocytes
inferredcites →https://doi.org/10.1016/s0022-3468(66)80019-2openalex-snapshot
The pathogenesis of cleft palate
inferredcites →https://doi.org/10.1016/s0092-8674(01)00336-1openalex-snapshot
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
inferredcites →https://doi.org/10.1016/s0168-9525(02)02770-1openalex-snapshot
Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?
inferredcites →https://doi.org/10.1016/s0925-4773(03)00004-2openalex-snapshot
The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation
inferredcites →https://doi.org/10.1016/s1535-6108(02)00045-4openalex-snapshot
Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma
inferredcites →https://doi.org/10.1016/s1535-6108(03)00268-xopenalex-snapshot
Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue
inferredcites →https://doi.org/10.1038/78099openalex-snapshot
Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk
inferredcites →https://doi.org/10.1038/8792openalex-snapshot
Sox9 is required for cartilage formation
inferredcites →https://doi.org/10.1038/sj.embor.7400386openalex-snapshot
Fyn/Yes and non‐canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements
inferredcites →https://doi.org/10.1046/j.1365-2443.2000.00300.xopenalex-snapshot
Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation
inferredcites →https://doi.org/10.1046/j.1365-2443.2003.00662.xopenalex-snapshot
The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway
inferredcites →https://doi.org/10.1073/pnas.1631288100openalex-snapshot
Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest
inferredcites →https://doi.org/10.1083/jcb.133.5.1123openalex-snapshot
Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development.
inferredcites →https://doi.org/10.1083/jcb.200303158openalex-snapshot
Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation
inferredcites →https://doi.org/10.1083/jcb.200306024openalex-snapshot
TGFβ3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development
inferredcites →https://doi.org/10.1083/jcb.200607127openalex-snapshot
Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration
inferredcites →https://doi.org/10.1086/382196openalex-snapshot
Homozygous WNT3 Mutation Causes Tetra-Amelia in a Large Consanguineous Family
inferredcites →https://doi.org/10.1093/molehr/gam034openalex-snapshot
FGF 10 and Sprouty 2 modulate trophoblast invasion and branching morphogenesis
inferredcites →https://doi.org/10.1095/biolreprod.105.042739openalex-snapshot
Mice Null for Frizzled4 (Fzd4−/−) Are Infertile and Exhibit Impaired Corpora Lutea Formation and Function1
inferredcites →https://doi.org/10.1101/gad.11.24.3286openalex-snapshot
Wnt signaling: a common theme in animal development
inferredcites →https://doi.org/10.1111/j.1365-2443.2007.01128.xopenalex-snapshot
Wnt5a modulates glycogen synthase kinase 3 to induce phosphorylation of receptor tyrosine kinase Ror2
inferredcites →https://doi.org/10.1111/j.1469-7580.2005.00474.xopenalex-snapshot
Regional regulation of palatal growth and patterning along the anterior–posterior axis in mice
inferredcites →https://doi.org/10.1111/j.1741-4520.2006.00103.xopenalex-snapshot
Regional heterogeneity in the developing palate: morphological and molecular evidence for normal and abnormal palatogenesis
inferredcites →https://doi.org/10.1126/science.1151250openalex-snapshot
Wnt5a Control of Cell Polarity and Directional Movement by Polarized Redistribution of Adhesion Receptors
inferredcites →https://doi.org/10.1172/jci200420384openalex-snapshot
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate
inferredcites →https://doi.org/10.1186/1741-7007-3-23openalex-snapshot
Wnt5 signaling in vertebrate pancreas development
inferredcites →https://doi.org/10.1242/dev.005132openalex-snapshot
Wnt signaling mediates regional specification in the vertebrate face
inferredcites →https://doi.org/10.1242/dev.008250openalex-snapshot
Wnt5a is required for proper mammary gland development and TGF-β-mediated inhibition of ductal growth
inferredcites →https://doi.org/10.1242/dev.02013openalex-snapshot
Shox2-deficient mice exhibit a rare type of incomplete clefting of the secondary palate
inferredcites →https://doi.org/10.1242/dev.119.1.97openalex-snapshot
Xwnt -5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis
inferredcites →https://doi.org/10.1242/dev.122.10.3035openalex-snapshot
Msx1 controls inductive signaling in mammalian tooth morphogenesis
inferredcites →https://doi.org/10.1242/dev.126.17.3869openalex-snapshot
Pathogenesis of cleft palate in TGF-β3 knockout mice
inferredcites →https://doi.org/10.1242/dev.126.20.4557openalex-snapshot
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
inferredcites →https://doi.org/10.1242/dev.126.6.1211openalex-snapshot
A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo
inferredcites →https://doi.org/10.1242/dev.129.17.4135openalex-snapshot
Rescue of cleft palate inMsx1-deficient mice by transgenicBmp4reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis
inferredcites →https://doi.org/10.1371/journal.pbio.0040115openalex-snapshot
Purified Wnt5a Protein Activates or Inhibits β-Catenin–TCF Signaling Depending on Receptor Context
inferredcites →https://doi.org/10.1387/ijdb.12068957openalex-snapshot
TGF-beta3 is required for the adhesion and intercalation of medial edge epithelial cells during palate fusion
inferredcites →https://doi.org/10.1523/jneurosci.1175-06.2006openalex-snapshot
The Wnt Receptor Ryk Is Required for Wnt5a-Mediated Axon Guidance on the Contralateral Side of the Corpus Callosum
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/1873-3468.12963openalex-snapshot
Disruption of Wnt production in Shh lineage causes bone malformation in mice, mimicking human Malik–Percin‐type syndactyly
inferred← citeshttps://doi.org/10.1002/9780470015902.a0020915.pub2openalex-snapshot
Craniofacial Defects and Cleft Lip and Palate
inferred← citeshttps://doi.org/10.1002/ajmg.a.62748openalex-snapshot
High prevalence of deleterious mutations in concomitant nonsyndromic cleft and outflow tract heart defects
inferred← citeshttps://doi.org/10.1002/bdr2.1754openalex-snapshot
Genetics and signaling mechanisms of orofacial clefts
inferred← citeshttps://doi.org/10.1002/bdr2.1853openalex-snapshot
Lithium‐induced overexpression of β‐catenin delays murine palatal shelf elevation by Cdc‐42 mediated F‐actin remodeling in mesenchymal cells
inferred← citeshttps://doi.org/10.1002/bdr2.2244openalex-snapshot
Retinoic acid delays murine palatal shelf elevation by inhibiting Wnt5a‐mediated noncanonical Wnt signaling and downstream Cdc‐42/F‐actin remodeling in mesenchymal cells
inferred← citeshttps://doi.org/10.1002/bdra.23079openalex-snapshot
A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects
inferred← citeshttps://doi.org/10.1002/bdra.23126openalex-snapshot
Developmental profiles of the murine palatal methylome
inferred← citeshttps://doi.org/10.1002/bdrb.20261openalex-snapshot
Effects of the histamine H1 antagonist chlorcyclizine on rat fetal palate development
inferred← citeshttps://doi.org/10.1002/bdrc.20180openalex-snapshot
Palate morphogenesis: Current understanding and future directions
inferred← citeshttps://doi.org/10.1002/dvdy.151openalex-snapshot
Role of noncanonical Wnt ligands and Ror‐family receptor tyrosine kinases in the development, regeneration, and diseases of the musculoskeletal system
inferred← citeshttps://doi.org/10.1002/dvdy.21934openalex-snapshot
Expression of WNT signalling pathway genes during chicken craniofacial development
inferred← citeshttps://doi.org/10.1002/dvdy.21991openalex-snapshot
Ror‐family receptor tyrosine kinases in noncanonical Wnt signaling: Their implications in developmental morphogenesis and human diseases
inferred← citeshttps://doi.org/10.1002/dvdy.22156openalex-snapshot
WNT5A mutations in patients with autosomal dominant Robinow syndrome
inferred← citeshttps://doi.org/10.1002/dvdy.22212openalex-snapshot
Ror2 is required for midgut elongation during mouse development
inferred← citeshttps://doi.org/10.1002/dvdy.22336openalex-snapshot
Expression of Gpr177, a Wnt trafficking regulator, in mouse embryogenesis
inferred← citeshttps://doi.org/10.1002/dvdy.22339openalex-snapshot
Mesenchymal cell remodeling during mouse secondary palate reorientation
inferred← citeshttps://doi.org/10.1002/dvdy.22362openalex-snapshot
Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded
inferred← citeshttps://doi.org/10.1002/dvdy.22466openalex-snapshot
Gsk3β is required in the epithelium for palatal elevation in mice
inferred← citeshttps://doi.org/10.1002/dvdy.22550openalex-snapshot
Wnt5a regulates growth, patterning, and odontoblast differentiation of developing mouse tooth
inferred← citeshttps://doi.org/10.1002/dvdy.24224openalex-snapshot
Palatogenesis and cutaneous repair: A two‐headed coin
inferred← citeshttps://doi.org/10.1002/dvdy.24376openalex-snapshot
Ectodermal Wnt controls nasal pit morphogenesis through modulation of the BMP/FGF/JNK signaling axis
inferred← citeshttps://doi.org/10.1002/dvg.22397openalex-snapshot
Generation of Shox2‐Cre allele for tissue specific manipulation of genes in the developing heart, palate, and limb
inferred← citeshttps://doi.org/10.1002/dvg.23441openalex-snapshot
Sox9CreER ‐mediated deletion of β‐catenin in palatal mesenchyme results in delayed palatal elevation accompanied with repressed canonical Wnt signaling and reduced actin polymerization
inferred← citeshttps://doi.org/10.1002/glia.23086openalex-snapshot
Critical role of Ror2 receptor tyrosine kinase in regulating cell cycle progression of reactive astrocytes following brain injury
inferred← citeshttps://doi.org/10.1002/glia.24483openalex-snapshot
Wnt5a/Ror2 promotes Nrf2‐mediated tissue protective function of astrocytes after brain injury
inferred← citeshttps://doi.org/10.1002/jcb.23044openalex-snapshot
Effects of phenytoin and Echinacea purpurea extract on proliferation and apoptosis of mouse embryonic palatal mesenchymal cells
inferred← citeshttps://doi.org/10.1002/jcb.28251openalex-snapshot
Perspective into the regulation of cell‐generated forces toward stem cell migration and differentiation
inferred← citeshttps://doi.org/10.1002/mgg3.53openalex-snapshot
Analysis of PRICKLE 1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations
inferred← citeshttps://doi.org/10.1002/pbc.22201openalex-snapshot
Role of Wnt inhibitory factor‐1 and Wnt/wingless signaling in choroid plexus tumors
inferred← citeshttps://doi.org/10.1007/164_2021_532openalex-snapshot
WNT Signaling Is a Key Player in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1007/978-1-0716-1847-9_6openalex-snapshot
Methods of Palate Culture in Later Palatogenesis: Elevation, Horizontal Outgrowth, and Fusion
inferred← citeshttps://doi.org/10.1007/978-1-4939-2053-2_11openalex-snapshot
Mouse Models of Receptor Tyrosine Kinases
inferred← citeshttps://doi.org/10.1007/978-3-030-46024-2_8openalex-snapshot
Fundamental Mechanisms of Orofacial Clefts
inferred← citeshttps://doi.org/10.1007/s00223-026-01566-yopenalex-snapshot
The Important Role of Polycystin in the Skeletal System
inferred← citeshttps://doi.org/10.1007/s00441-014-1925-6openalex-snapshot
Prickle1 is necessary for the caudal migration of murine facial branchiomotor neurons
inferred← citeshttps://doi.org/10.1007/s00441-015-2169-9openalex-snapshot
Role of region-distinctive expression of Rac1 in regulating fibronectin arrangement during palatal shelf elevation
inferred← citeshttps://doi.org/10.1007/s00441-018-2944-5openalex-snapshot
Conditional deletion of Bmp2 in cranial neural crest cells recapitulates Pierre Robin sequence in mice
inferred← citeshttps://doi.org/10.1007/s00795-021-00297-3openalex-snapshot
The concurrent stimulation of Wnt and FGF8 signaling induce differentiation of dental mesenchymal cells into odontoblast-like cells
inferred← citeshttps://doi.org/10.1007/s10456-026-10068-2openalex-snapshot
MCC links Wnt/PCP signaling to endothelial polarity and vascular remodeling
inferred← citeshttps://doi.org/10.1007/s13105-013-0262-7openalex-snapshot
Down-regulation of Wnt10a by RNA interference inhibits proliferation and promotes apoptosis in mouse embryonic palatal mesenchymal cells through Wnt/β-catenin signaling pathway
inferred← citeshttps://doi.org/10.1007/s13277-015-4470-3openalex-snapshot
Wnt5a and Ror2 expression associate with the disease progress of primary thyroid lymphoma
inferred← citeshttps://doi.org/10.1007/s13277-015-4471-2openalex-snapshot
Wnt5a and Ror2 expression associate with the disease progress of primary thyroid lymphoma
inferred← citeshttps://doi.org/10.1007/s13402-022-00757-7openalex-snapshot
WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma
inferred← citeshttps://doi.org/10.1016/b978-0-12-394592-1.00008-9openalex-snapshot
Wnt Regulation of Planar Cell Polarity (PCP)
inferred← citeshttps://doi.org/10.1016/b978-0-12-397157-9.00042-4openalex-snapshot
Molecular Strategies in the Study and Repair of Palatal Defects
inferred← citeshttps://doi.org/10.1016/b978-0-443-23739-3.00029-8openalex-snapshot
Regulatory mechanisms of palate and tongue development
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2014.11.005openalex-snapshot
Receptor Tyrosine Kinase Signaling
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2016.09.003openalex-snapshot
ROR-Family Receptor Tyrosine Kinases
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2023.01.009openalex-snapshot
Non-canonical WNT5A-ROR signaling: New perspectives on an ancient developmental pathway
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2014.10.003openalex-snapshot
Insight into the Role of Wnt5a-Induced Signaling in Normal and Cancer Cells
inferred← citeshttps://doi.org/10.1016/j.aanat.2026.152858openalex-snapshot
Palatal shelf integrated into tissue segment derived from maxillary process: A comparative study of the growth of its parts during the human embryonic period
inferred← citeshttps://doi.org/10.1016/j.ajpath.2013.07.034openalex-snapshot
Reactivation of NCAM1 Defines a Subpopulation of Human Adult Kidney Epithelial Cells with Clonogenic and Stem/Progenitor Properties
inferred← citeshttps://doi.org/10.1016/j.archoralbio.2017.06.019openalex-snapshot
The secreted protein WNT5A regulates condylar chondrocyte proliferation, hypertrophy and migration
inferred← citeshttps://doi.org/10.1016/j.bbadis.2015.08.007openalex-snapshot
Congenital Short Bowel Syndrome: from clinical and genetic diagnosis to the molecular mechanisms involved in intestinal elongation
inferred← citeshttps://doi.org/10.1016/j.bbrc.2015.01.148openalex-snapshot
Retinoic acid inhibits histone methyltransferase Whsc1 during palatogenesis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.10.079openalex-snapshot
Inhibition of the Zeb family prevents murine palatogenesis through regulation of apoptosis and the cell cycle
inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.04.090openalex-snapshot
Increased miR-200c levels disrupt palatal fusion by affecting apoptosis, cell proliferation, and cell migration
inferred← citeshttps://doi.org/10.1016/j.bone.2024.117038openalex-snapshot
The role of Map1b in regulating osteoblast polarity, proliferation, differentiation and migration
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.110935openalex-snapshot
Deciphering the origins and fates of steroidogenic lineages in the mouse testis
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.113354openalex-snapshot
Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
inferred← citeshttps://doi.org/10.1016/j.csbj.2025.09.031openalex-snapshot
Single-cell multiome characterizing intercellular communication and intracellular regulation of epithelium and mesenchymal during secondary palate development in mice
inferred← citeshttps://doi.org/10.1016/j.dib.2018.03.010openalex-snapshot
Gene datasets associated with mouse cleft palate
inferred← citeshttps://doi.org/10.1016/j.diff.2016.05.001openalex-snapshot
Retinoic acid signalling in the development of the epidermis, the limbs and the secondary palate
inferred← citeshttps://doi.org/10.1016/j.gde.2013.05.003openalex-snapshot
Planar cell polarity in vertebrate limb morphogenesis
inferred← citeshttps://doi.org/10.1016/j.isci.2025.111972openalex-snapshot
Fine-tuning of Wnt signaling by RNA surveillance factor Smg5 in the mouse craniofacial development
inferred← citeshttps://doi.org/10.1016/j.jgg.2021.07.006openalex-snapshot
Essential role of Msx1 in regulating anterior-posterior patterning of the secondary palate in mice
inferred← citeshttps://doi.org/10.1016/j.matbio.2013.02.005openalex-snapshot
Dual functions for WNT5A during cartilage development and in disease
inferred← citeshttps://doi.org/10.1016/j.mce.2009.06.002openalex-snapshot
Is Wnt signalling the final common pathway leading to bone formation?
inferred← citeshttps://doi.org/10.1016/j.mod.2010.11.003openalex-snapshot
Zebrafish wnt9a is expressed in pharyngeal ectoderm and is required for palate and lower jaw development
inferred← citeshttps://doi.org/10.1016/j.mod.2012.07.004openalex-snapshot
Rgs19 regulates mouse palatal fusion by modulating cell proliferation and apoptosis in the MEE
inferred← citeshttps://doi.org/10.1016/j.placenta.2010.01.012openalex-snapshot
Orphan Receptor Kinase ROR2 is Expressed in the Mouse Uterus
inferred← citeshttps://doi.org/10.1016/j.reprotox.2010.10.006openalex-snapshot
TGFβ-1 and Wnt-3a interact to induce unique gene expression profiles in murine embryonic palate mesenchymal cells
inferred← citeshttps://doi.org/10.1016/j.reprotox.2014.10.018openalex-snapshot
Strain-dependent effects of transforming growth factor-β1 and 2 during mouse secondary palate development
inferred← citeshttps://doi.org/10.1016/j.reprotox.2018.03.004openalex-snapshot
Inactivation of Fgfr2 gene in mouse secondary palate mesenchymal cells leads to cleft palate
inferred← citeshttps://doi.org/10.1016/j.tcb.2010.03.001openalex-snapshot
Cell/tissue-tropic functions of Wnt5a signaling in normal and cancer cells
inferred← citeshttps://doi.org/10.1016/j.tice.2022.101783openalex-snapshot
Comparative analysis of mouse embryonic palatal mesenchymal cells isolated by two primary culture methods
inferred← citeshttps://doi.org/10.1016/j.ydbio.2009.09.020openalex-snapshot
Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse
inferred← citeshttps://doi.org/10.1016/j.ydbio.2009.09.028openalex-snapshot
Signaling integration in the rugae growth zone directs sequential SHH signaling center formation during the rostral outgrowth of the palate
inferred← citeshttps://doi.org/10.1016/j.ydbio.2009.11.021openalex-snapshot
New directions in craniofacial morphogenesis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2010.08.014openalex-snapshot
Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2010.10.023openalex-snapshot
BmprIa is required in mesenchymal tissue and has limited redundant function with BmprIb in tooth and palate development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2010.12.021openalex-snapshot
Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.01.004openalex-snapshot
The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal–mesenchymal interaction
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.10.009openalex-snapshot
Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.06.020openalex-snapshot
Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2013.02.013openalex-snapshot
An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation
inferred← citeshttps://doi.org/10.1016/j.ydbio.2018.02.002openalex-snapshot
Notum attenuates Wnt/β–catenin signaling to promote tracheal cartilage patterning
inferred← citeshttps://doi.org/10.1016/j.yexcr.2010.12.015openalex-snapshot
Wnt signalling mediates the cross-talk between bone marrow derived pre-adipocytic and pre-osteoblastic cell populations
inferred← citeshttps://doi.org/10.1016/j.yexcr.2016.02.015openalex-snapshot
Inhibition of p300 histone acetyltransferase activity in palate mesenchyme cells attenuates Wnt signaling via aberrant E-cadherin expression
inferred← citeshttps://doi.org/10.1038/onc.2009.175openalex-snapshot
Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling
inferred← citeshttps://doi.org/10.1038/onc.2009.305openalex-snapshot
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma
inferred← citeshttps://doi.org/10.1038/s41368-022-00188-yopenalex-snapshot
Bone morphogenetic protein 7 mediates stem cells migration and angiogenesis: therapeutic potential for endogenous pulp regeneration
inferred← citeshttps://doi.org/10.1038/s41398-017-0057-7openalex-snapshot
Common basis for orofacial clefting and cortical interneuronopathy
inferred← citeshttps://doi.org/10.1038/s41598-021-81123-9openalex-snapshot
SPECC1L-deficient primary mouse embryonic palatal mesenchyme cells show speed and directionality defects
inferred← citeshttps://doi.org/10.1038/s41598-024-76069-7openalex-snapshot
DPP an extracellular matrix molecule induces Wnt5a mediated signaling to promote the differentiation of adult stem cells into odontogenic lineage
inferred← citeshttps://doi.org/10.1074/jbc.m113.522003openalex-snapshot
Avian Facial Morphogenesis Is Regulated by c-Jun N-terminal Kinase/Planar Cell Polarity (JNK/PCP) Wingless-related (WNT) Signaling
inferred← citeshttps://doi.org/10.1074/jbc.m115.701177openalex-snapshot
The A-kinase Anchoring Protein GSKIP Regulates GSK3β Activity and Controls Palatal Shelf Fusion in Mice
inferred← citeshttps://doi.org/10.1074/jbc.m117.785709openalex-snapshot
The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle
inferred← citeshttps://doi.org/10.1080/08941939.2017.1383536openalex-snapshot
A Review of Primary Thyroid Lymphoma: Molecular Factors, Diagnosis and Management
inferred← citeshttps://doi.org/10.1080/14647273.2023.2251678openalex-snapshot
Tissue engineering studies in male infertility disorder
inferred← citeshttps://doi.org/10.1091/mbc.e09-05-0415openalex-snapshot
Dkk-1 Inhibits Intestinal Epithelial Cell Migration by Attenuating Directional Polarization of Leading Edge Cells
inferred← citeshttps://doi.org/10.1093/hmg/ddab211openalex-snapshot
In-frame deletion of SPECC1L microtubule association domain results in gain-of-function phenotypes affecting embryonic tissue movement and fusion events
inferred← citeshttps://doi.org/10.1093/hmg/ddq462openalex-snapshot
Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B
inferred← citeshttps://doi.org/10.1093/hmg/ddv088openalex-snapshot
A mutation in FRIZZLED2 impairs Wnt signaling and causes autosomal dominant omodysplasia
inferred← citeshttps://doi.org/10.1093/nar/gkq037openalex-snapshot
Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon
inferred← citeshttps://doi.org/10.1095/biolreprod.111.095232openalex-snapshot
Loss of Wnt5a Disrupts Primordial Germ Cell Migration and Male Sexual Development in Mice1
inferred← citeshttps://doi.org/10.1096/fj.201902849ropenalex-snapshot
E2F1‐Ror2 signaling mediates coordinated transcriptional regulation to promote G1/S phase transition in bFGF‐stimulated NIH/3T3 fibroblasts
inferred← citeshttps://doi.org/10.1096/fj.202001597ropenalex-snapshot
Prospects of circadian clock in joint cartilage development
inferred← citeshttps://doi.org/10.1097/sap.0b013e318295dcb8openalex-snapshot
Targeted Mutations of Genes Reveal Important Roles in Palatal Development in Mice
inferred← citeshttps://doi.org/10.1101/2020.02.05.935189openalex-snapshot
Foxg1 Organizes Cephalic Ectoderm to Repress Mandibular Fate, Regulate Apoptosis, Generate Choanae, Elaborate the Auxiliary Eye and Pattern the Upper Jaw
inferred← citeshttps://doi.org/10.1101/2020.07.25.221069openalex-snapshot
Expression of Wnt5a defines the major progenitors of fetal and adult Leydig cells
inferred← citeshttps://doi.org/10.1101/2020.09.10.292359openalex-snapshot
Cellular mechanisms of chick limb bud morphogenesis
inferred← citeshttps://doi.org/10.1101/2021.01.28.428634openalex-snapshot
In-frame deletion of SPECC1L microtubule binding domain results in embryonic tissue movement and fusion defects
inferred← citeshttps://doi.org/10.1101/2021.10.25.465629openalex-snapshot
The Isl1/Shh/Wnt5a cascade controls the invasion of myoblasts by tuning the CXCL12/CXCR4 axis during tongue morphogenesis
inferred← citeshttps://doi.org/10.1101/2025.03.25.645191openalex-snapshot
Cell polarity of neural crest-derived mesenchymal cells controls craniofacial development
inferred← citeshttps://doi.org/10.1101/cshperspect.a002964openalex-snapshot
Planar Cell Polarity Signaling: The Developing Cell's Compass
inferred← citeshttps://doi.org/10.1111/cga.12438openalex-snapshot
Stage‐dependent function of Wnt5a during male external genitalia development
inferred← citeshttps://doi.org/10.1111/cge.13141openalex-snapshot
Common variants in DLG1 locus are associated with non‐syndromic cleft lip with or without cleft palate
inferred← citeshttps://doi.org/10.1111/dgd.12851openalex-snapshot
Live imaging observation of elevation of the anterior palatal shelf in mouse embryos
inferred← citeshttps://doi.org/10.1111/gtc.12676openalex-snapshot
Genetic interactions between Ror2 and Wnt9a, Ror1 and Wnt9a and Ror2 and Ror1: Phenotypic analysis of the limb skeleton and palate in compound mutants
inferred← citeshttps://doi.org/10.1111/j.1365-2443.2011.01487.xopenalex-snapshot
Critical role of Wnt5a-Ror2 signaling in motility and invasiveness of carcinoma cells following Snail-mediated epithelial-mesenchymal transition
inferred← citeshttps://doi.org/10.1111/j.1600-0722.2011.00938.xopenalex-snapshot
Genotype and haplotype analysis of WNT genes in non‐syndromic cleft lip with or without cleft palate
inferred← citeshttps://doi.org/10.1111/j.1748-1716.2011.02297.xopenalex-snapshot
Wnt11 in 2011 – the regulation and function of a non‐canonical Wnt
inferred← citeshttps://doi.org/10.1111/joa.12291openalex-snapshot
Diversity in primary palate ontogeny of amniotes revealed with 3D imaging
inferred← citeshttps://doi.org/10.1111/joa.12425openalex-snapshot
Mapping cellular processes in the mesenchyme during palatal development in the absence of Tbx1 reveals complex proliferation changes and perturbed cell packing and polarity
inferred← citeshttps://doi.org/10.1111/nyas.14293openalex-snapshot
Deletion of Wnt5a in osteoclasts results in bone loss through decreased bone formation
inferred← citeshttps://doi.org/10.1111/odi.14174openalex-snapshot
Revisiting the embryogenesis of lip and palate development
inferred← citeshttps://doi.org/10.1126/sciadv.aec2511openalex-snapshot
Cis-regulatory evolution shapes facial diversity in birds and mammals
inferred← citeshttps://doi.org/10.1126/scitranslmed.aax3063openalex-snapshot
ROR2 blockade as a therapy for osteoarthritis
inferred← citeshttps://doi.org/10.1128/mcb.00177-10openalex-snapshot
Ror2/Frizzled Complex Mediates Wnt5a-Induced AP-1 Activation by Regulating Dishevelled Polymerization
inferred← citeshttps://doi.org/10.1128/mcb.00491-14openalex-snapshot
Role of Wnt5a-Ror2 Signaling in Morphogenesis of the Metanephric Mesenchyme during Ureteric Budding
inferred← citeshttps://doi.org/10.1136/jmedgenet-2015-103619openalex-snapshot
A splicing mutation in VPS4B causes dentin dysplasia I
inferred← citeshttps://doi.org/10.1139/bcb-2016-0216openalex-snapshot
Wnt5A regulates the expression of ROR2 tyrosine kinase receptor in ovarian cancer cells
inferred← citeshttps://doi.org/10.1152/ajprenal.00566.2009openalex-snapshot
Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes
inferred← citeshttps://doi.org/10.1155/2020/6758934openalex-snapshot
Long Noncoding RNA TUG1 Promotes the Function in ox-LDL-Treated HA-VSMCs via miR-141-3p/ROR2 Axis
inferred← citeshttps://doi.org/10.1159/000323213openalex-snapshot
Occurrence of Cleft-Palate and Alteration of Tgf-β3 Expression and the Mechanisms Leading to Palatal Fusion in Mice following Dietary Folic-Acid Deficiency
inferred← citeshttps://doi.org/10.1159/000337523openalex-snapshot
The Mouse as a Developmental Model for Cleft Lip and Palate Research
inferred← citeshttps://doi.org/10.1159/000337619openalex-snapshot
Wnt Signaling in Lip and Palate Development
inferred← citeshttps://doi.org/10.11606/t.41.2016.tde-01082016-100632openalex-snapshot
Variantes genéticas de risco às fissuras orofaciais
inferred← citeshttps://doi.org/10.1172/jci83535openalex-snapshot
Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation
inferred← citeshttps://doi.org/10.1177/0022034515583532openalex-snapshot
Gpr177-mediated Wnt Signaling Is Required for Secondary Palate Development
inferred← citeshttps://doi.org/10.1177/0022034517703580openalex-snapshot
Molecular and Cellular Mechanisms of Palate Development
inferred← citeshttps://doi.org/10.1177/0022034517716916openalex-snapshot
Abnormal WNT5A Signaling Causes Mandibular Hypoplasia in Robinow Syndrome
inferred← citeshttps://doi.org/10.1177/0022034517719865openalex-snapshot
Modulating Wnt Signaling Rescues Palate Morphogenesis in Pax9 Mutant Mice
inferred← citeshttps://doi.org/10.1177/0022034518811861openalex-snapshot
The Function and Regulatory Network of Pax9 Gene in Palate Development
inferred← citeshttps://doi.org/10.1177/0022034519872478openalex-snapshot
Requirement of Hyaluronan Synthase-2 in Craniofacial and Palate Development
inferred← citeshttps://doi.org/10.1177/09636897251372397openalex-snapshot
Photobiomodulation-induced activation of Wnt signaling enhances differentiation of adipose-derived stem cells into tenocytes: Mechanistic insights into regenerative signaling pathways
inferred← citeshttps://doi.org/10.1177/1055665617732782openalex-snapshot
Association of WNT Pathway Genes With Nonsyndromic Cleft Lip With or Without Cleft Palate
inferred← citeshttps://doi.org/10.1177/10556656261464115openalex-snapshot
Association Study of Wnt Pathway Genes with Non-syndromic Orofacial Cleft in Han Chinese
inferred← citeshttps://doi.org/10.1177/1535370215584889openalex-snapshot
Wnt5a attenuates hypoxia-induced pulmonary arteriolar remodeling and right ventricular hypertrophy in mice
inferred← citeshttps://doi.org/10.1177/1947601912448820openalex-snapshot
Targeting of Noncanonical Wnt5a Signaling by AP-1 Blocker Dominant-Negative Jun When It Inhibits Skin Carcinogenesis
inferred← citeshttps://doi.org/10.1186/1471-213x-14-3openalex-snapshot
Neural crest-specific deletion of Ldb1 leads to cleft secondary palate with impaired palatal shelf elevation
inferred← citeshttps://doi.org/10.1186/1750-1326-5-3openalex-snapshot
Wnt-5aoccludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons
inferred← citeshttps://doi.org/10.1186/s11658-016-0003-3openalex-snapshot
WNT5A–ROR2 is induced by inflammatory mediators and is involved in the migration of human ovarian cancer cell line SKOV-3
inferred← citeshttps://doi.org/10.1186/s13287-019-1340-8openalex-snapshot
Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway
inferred← citeshttps://doi.org/10.1210/me.2010-0037openalex-snapshot
WNT5A Regulates Chondrocyte Differentiation through Differential Use of the CaN/NFAT and IKK/NF-κB Pathways
inferred← citeshttps://doi.org/10.1242/dev.046987openalex-snapshot
Oriented cell motility and division underlie early limb bud morphogenesis
inferred← citeshttps://doi.org/10.1242/dev.050591openalex-snapshot
Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation
inferred← citeshttps://doi.org/10.1242/dev.052001openalex-snapshot
Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes
inferred← citeshttps://doi.org/10.1242/dev.067082openalex-snapshot
Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development
inferred← citeshttps://doi.org/10.1242/dev.083352openalex-snapshot
Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes
inferred← citeshttps://doi.org/10.1242/dev.157750openalex-snapshot
Small-molecule Wnt agonists correct cleft palates in Pax9 mutant mice in utero
inferred← citeshttps://doi.org/10.1242/dev.196360openalex-snapshot
Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development
inferred← citeshttps://doi.org/10.1242/dev.200533openalex-snapshot
Single-cell transcriptomic signatures and gene regulatory networks modulated by Wls in mammalian midline facial formation and clefts
inferred← citeshttps://doi.org/10.1242/dev.200788openalex-snapshot
ISL1/SHH/CXCL12 signaling regulates myogenic cell migration during mouse tongue development
inferred← citeshttps://doi.org/10.1242/dmm.037051openalex-snapshot
Wnt signaling in orofacial clefts: crosstalk, pathogenesis and models
inferred← citeshttps://doi.org/10.1266/ggs.19-00029openalex-snapshot
Transposable elements as genetic accelerators of evolution: contribution to genome size, gene regulatory network rewiring and morphological innovation
inferred← citeshttps://doi.org/10.13188/2332-3442.1000014openalex-snapshot
Planar Polarity Factors as Potential Tumor Suppressors in the Urogenital Tract
inferred← citeshttps://doi.org/10.1371/journal.pgen.1002428openalex-snapshot
Ror2 Enhances Polarity and Directional Migration of Primordial Germ Cells
inferred← citeshttps://doi.org/10.1371/journal.pgen.1004479openalex-snapshot
Wnt Signaling Interacts with Bmp and Edn1 to Regulate Dorsal-Ventral Patterning and Growth of the Craniofacial Skeleton
inferred← citeshttps://doi.org/10.1371/journal.pgen.1006380openalex-snapshot
Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate
inferred← citeshttps://doi.org/10.1371/journal.pone.0011493openalex-snapshot
Maternal Genes and Facial Clefts in Offspring: A Comprehensive Search for Genetic Associations in Two Population-Based Cleft Studies from Scandinavia
inferred← citeshttps://doi.org/10.1371/journal.pone.0054410openalex-snapshot
Requirement for Dlgh-1 in Planar Cell Polarity and Skeletogenesis during Vertebrate Development
inferred← citeshttps://doi.org/10.1371/journal.pone.0066107openalex-snapshot
Augmented BMPRIA-Mediated BMP Signaling in Cranial Neural Crest Lineage Leads to Cleft Palate Formation and Delayed Tooth Differentiation
inferred← citeshttps://doi.org/10.1371/journal.pone.0080526openalex-snapshot
WNT5A Encodes Two Isoforms with Distinct Functions in Cancers
inferred← citeshttps://doi.org/10.1371/journal.pone.0136951openalex-snapshot
Altered FGF Signaling Pathways Impair Cell Proliferation and Elevation of Palate Shelves
inferred← citeshttps://doi.org/10.1371/journal.pone.0145169openalex-snapshot
A PTK7/Ror2 Co-Receptor Complex Affects Xenopus Neural Crest Migration
inferred← citeshttps://doi.org/10.1387/ijdb.140094jdopenalex-snapshot
Regional divergence of palate medial edge epithelium along the anterior to posterior axis
inferred← citeshttps://doi.org/10.15252/embj.2018101230openalex-snapshot
The Wnt/Ca2+ pathway is involved in interneuronal communication mediated by tunneling nanotubes
inferred← citeshttps://doi.org/10.1590/1678-7757-2023-0353openalex-snapshot
Exploring the role of the WNT5A rs566926 polymorphism and its interactions in non-syndromic orofacial cleft: a multicenter study in Brazil
inferred← citeshttps://doi.org/10.1597/13-018openalex-snapshot
2,3,7,8-Tetrachlorodibenzo-p-dioxin Delays Palatal Shelf Elevation and Suppresses Wnt5a and Lymphoid Enhancing-Binding Factor 1 Signaling in Developing Palate
inferred← citeshttps://doi.org/10.1597/13-146openalex-snapshot
Association of WNT9B Gene Polymorphisms with Nonsyndromic Cleft Lip with or Without Cleft Palate in Brazilian Nuclear Families
inferred← citeshttps://doi.org/10.17169/refubium-17041openalex-snapshot
Characterization of a BMP co-receptor
inferred← citeshttps://doi.org/10.18632/oncotarget.5643openalex-snapshot
Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion
inferred← citeshttps://doi.org/10.20396/bjos.v25i00.8677494openalex-snapshot
Relation of the WNT5A gene and non-syndromic orofacial clefts
inferred← citeshttps://doi.org/10.21037/atm-22-5772openalex-snapshot
Transcriptome sequencing analysis of the role of β-catenin in F-actin reorganization in embryonic palatal mesenchymal cells
inferred← citeshttps://doi.org/10.21451/1984-3143-ar904openalex-snapshot
Primordial germ cell migration and the Wnt signaling pathway
inferred← citeshttps://doi.org/10.2485/jhtb.20.133openalex-snapshot
Gene Expression Profiling of Retinoic Acid Induced Cleft Palate
inferred← citeshttps://doi.org/10.2741/3957openalex-snapshot
The Wnt signaling pathways and cell adhesion
inferred← citeshttps://doi.org/10.2741/4076openalex-snapshot
Regulation of endochondral ossification by transcription factors
inferred← citeshttps://doi.org/10.3389/fcell.2021.667581openalex-snapshot
WNT5B in Physiology and Disease
inferred← citeshttps://doi.org/10.3389/fcell.2022.838871openalex-snapshot
Lyn Phosphorylates and Controls ROR1 Surface Dynamics During Chemotaxis of CLL Cells
inferred← citeshttps://doi.org/10.3389/fcell.2022.891763openalex-snapshot
The Ror-Family Receptors in Development, Tissue Regeneration and Age-Related Disease
inferred← citeshttps://doi.org/10.3389/fcell.2024.1497002openalex-snapshot
Epithelial-mesenchymal crosstalk: the scriptwriter of craniofacial morphogenesis
inferred← citeshttps://doi.org/10.3389/fcell.2026.1740081openalex-snapshot
Persistent Wnt/β-catenin signaling disables soft palatogenesis and palatal osteogenesis by inducing mesenchymal condensation
inferred← citeshttps://doi.org/10.3389/fphys.2012.00488openalex-snapshot
Molecular signaling along the anterior–posterior axis of early palate development
inferred← citeshttps://doi.org/10.3389/fphys.2016.00060openalex-snapshot
Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue
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