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Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo

https://doi.org/10.1242/dev.038893
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/dvdy.20034openalex-snapshot
Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human
inferredcites →https://doi.org/10.1002/dvg.20442openalex-snapshot
Parameters influencing derivation of embryonic stem cells from murine embryos
inferredcites →https://doi.org/10.1006/dbio.1994.1312openalex-snapshot
Oct-4 Transcription Factor Is Differentially Expressed in the Mouse Embryo during Establishment of the First Two Extraembryonic Cell Lineages Involved in Implantation
inferredcites →https://doi.org/10.1006/dbio.1996.0165openalex-snapshot
GATA-6: A Zinc Finger Transcription Factor That Is Expressed in Multiple Cell Lineages Derived from Lateral Mesoderm
inferredcites →https://doi.org/10.1006/dbio.1999.9265openalex-snapshot
Suppression of SHP-2 and ERK Signalling Promotes Self-Renewal of Mouse Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/0925-4773(96)00531-xopenalex-snapshot
Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis
inferredcites →https://doi.org/10.1016/j.cell.2008.12.006openalex-snapshot
Germline Competent Embryonic Stem Cells Derived from Rat Blastocysts
inferredcites →https://doi.org/10.1016/j.cell.2008.12.007openalex-snapshot
Capture of Authentic Embryonic Stem Cells from Rat Blastocysts
inferredcites →https://doi.org/10.1016/j.cell.2009.07.039openalex-snapshot
Nanog Is the Gateway to the Pluripotent Ground State
inferredcites →https://doi.org/10.1016/j.devcel.2006.02.020openalex-snapshot
Early Lineage Segregation between Epiblast and Primitive Endoderm in Mouse Blastocysts through the Grb2-MAPK Pathway
inferredcites →https://doi.org/10.1016/j.devcel.2009.02.003openalex-snapshot
The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass
inferredcites →https://doi.org/10.1016/j.stem.2009.05.015openalex-snapshot
Naive and Primed Pluripotent States
inferredcites →https://doi.org/10.1016/s0076-6879(03)65023-8openalex-snapshot
Defined Conditions for Neural Commitment and Differentiation
inferredcites →https://doi.org/10.1016/s0092-8674(00)81702-xopenalex-snapshot
Mammalian Grb2 Regulates Multiple Steps in Embryonic Development and Malignant Transformation
inferredcites →https://doi.org/10.1016/s0092-8674(00)81769-9openalex-snapshot
Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4
inferredcites →https://doi.org/10.1016/s0092-8674(03)00392-1openalex-snapshot
Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/s0092-8674(03)00393-3openalex-snapshot
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
inferredcites →https://doi.org/10.1016/s0092-8674(03)00847-xopenalex-snapshot
BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3
inferredcites →https://doi.org/10.1038/292154a0openalex-snapshot
Establishment in culture of pluripotential cells from mouse embryos
inferredcites →https://doi.org/10.1038/309255a0openalex-snapshot
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
inferredcites →https://doi.org/10.1038/336684a0openalex-snapshot
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
inferredcites →https://doi.org/10.1038/336688a0openalex-snapshot
Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
inferredcites →https://doi.org/10.1038/nature05950openalex-snapshot
Derivation of pluripotent epiblast stem cells from mammalian embryos
inferredcites →https://doi.org/10.1038/nature05972openalex-snapshot
New cell lines from mouse epiblast share defining features with human embryonic stem cells
inferredcites →https://doi.org/10.1038/nature06968openalex-snapshot
The ground state of embryonic stem cell self-renewal
inferredcites →https://doi.org/10.1038/ng.173openalex-snapshot
Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos
inferredcites →https://doi.org/10.1038/nm.1996openalex-snapshot
Validated germline-competent embryonic stem cell lines from nonobese diabetic mice
inferredcites →https://doi.org/10.1038/sj.onc.1210473openalex-snapshot
Indirubin-3′-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
inferredcites →https://doi.org/10.1042/bj20070797openalex-snapshot
The selectivity of protein kinase inhibitors: a further update
inferredcites →https://doi.org/10.1073/pnas.0608156103openalex-snapshot
Self-renewal of embryonic stem cells by a small molecule
inferredcites →https://doi.org/10.1073/pnas.0712136105openalex-snapshot
X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells
inferredcites →https://doi.org/10.1073/pnas.72.12.5099openalex-snapshot
Immunosurgery of mouse blastocyst.
inferredcites →https://doi.org/10.1073/pnas.78.12.7634openalex-snapshot
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.
inferredcites →https://doi.org/10.1073/pnas.94.11.5709openalex-snapshot
The origin and efficient derivation of embryonic stem cells in the mouse
inferredcites →https://doi.org/10.1073/pnas.95.9.5082openalex-snapshot
Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development
inferredcites →https://doi.org/10.1093/biolreprod/8.4.491openalex-snapshot
Determining the Stage of the Estrous Cycle in the Mouse by the Appearance of the Vagina
inferredcites →https://doi.org/10.1095/biolreprod.102.006197openalex-snapshot
Rapid Loss of Oct-4 and Pluripotency in Cultured Rodent Blastocysts and Derivative Cell Lines1
inferredcites →https://doi.org/10.1098/rstb.2003.1327openalex-snapshot
Genesis of embryonic stem cells
inferredcites →https://doi.org/10.1126/science.1092674openalex-snapshot
Reactivation of the Paternal X Chromosome in Early Mouse Embryos
inferredcites →https://doi.org/10.1126/science.1092727openalex-snapshot
Epigenetic Dynamics of Imprinted X Inactivation During Early Mouse Development
inferredcites →https://doi.org/10.1126/science.1149185openalex-snapshot
Profiling Essential Genes in Human Mammary Cells by Multiplex RNAi Screening
inferredcites →https://doi.org/10.1126/science.282.5396.2072openalex-snapshot
Promotion of Trophoblast Stem Cell Proliferation by FGF4
inferredcites →https://doi.org/10.1242/dev.010223openalex-snapshot
Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development
inferredcites →https://doi.org/10.1242/dev.01586openalex-snapshot
A germ cell origin of embryonic stem cells?
inferredcites →https://doi.org/10.1242/dev.01801openalex-snapshot
Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst
inferredcites →https://doi.org/10.1242/dev.02880openalex-snapshot
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment
inferredcites →https://doi.org/10.1242/dev.030957openalex-snapshot
Klf4 reverts developmentally programmed restriction of ground state pluripotency
inferredcites →https://doi.org/10.1242/dev.120.5.1335openalex-snapshot
msd is required for mesoderm induction in mice
inferredcites →https://doi.org/10.1242/dev.120.8.2259openalex-snapshot
Expression and function of FGF-4 in peri-implantation development in mouse embryos
inferredcites →https://doi.org/10.1242/dev.127.24.5449openalex-snapshot
Taube nuss is a novel gene essential for the survival of pluripotent cells of early mouse embryos
inferredcites →https://doi.org/10.1242/dev.88.1.303openalex-snapshot
Regeneration of endoderm from primitive ectoderm in the mouse embryo: fact or artifact?
inferredcites →https://doi.org/10.1371/journal.pbio.0060253openalex-snapshot
Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition
inferredcites →https://doi.org/10.1385/1-59745-037-5:91openalex-snapshot
Derivation and Propagation of Embryonic Stem Cells in Serum- and Feeder-Free Culture
inferredcites →https://doi.org/10.1387/ijdb.7981049openalex-snapshot
Strain difference in establishment of mouse embryonic stem (ES) cell lines
inferredcites →https://doi.org/10.1387/ijdb.9184330openalex-snapshot
Reflections on the biology of embryonic stem (ES) cells
inferredcites →https://doi.org/10.1530/jrf.0.0660161openalex-snapshot
Preservation of hamster oocytes to assay the fertilizing capacity of human spermatozoa
inferredcites →https://doi.org/10.1634/stemcells.2007-0086openalex-snapshot
Efficient Derivation of Embryonic Stem Cells by Inhibition of Glycogen Synthase Kinase-3

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4750446openalex-extracted
STAT3 Signalling Drives Tissue Expansion During Postimplantation Mouse Development
inferred← citeshttps://doi.org/10.1002/9780470889909.ch26openalex-snapshot
Human Pluripotent Cells: The Biology of Pluripotency
inferred← citeshttps://doi.org/10.1002/adma.201505723openalex-snapshot
Directed Assembly and Development of Material‐Free Tissues with Complex Architectures
inferred← citeshttps://doi.org/10.1002/advs.202407971openalex-snapshot
LIF Promotes Sec15b‐Mediated STAT3 Exosome Secretion to Maintain Stem Cell Pluripotency in Mouse Embryonic Development
inferred← citeshttps://doi.org/10.1002/ajmg.a.35573openalex-snapshot
Assessing pre‐implantation embryo development in mice provides a rationale for understanding potential adverse effects of ART and PGD procedures
inferred← citeshttps://doi.org/10.1002/bies.201100018openalex-snapshot
Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models
inferred← citeshttps://doi.org/10.1002/bies.201200162openalex-snapshot
Would the real human embryonic stem cell please stand up?
inferred← citeshttps://doi.org/10.1002/bies.202400077openalex-snapshot
Relationship of PSC to embryos: Extending and refining capture of PSC lines from mammalian embryos
inferred← citeshttps://doi.org/10.1002/bies.202400108openalex-snapshot
Propagating pluripotency – The conundrum of self‐renewal
inferred← citeshttps://doi.org/10.1002/cbin.10411openalex-snapshot
Reprogramming of endometrial adult stromal cells in the presence of a ROCK inhibitor, thiazovivin, could obtain more efficient iPSCs
inferred← citeshttps://doi.org/10.1002/cbin.10847openalex-snapshot
Simultaneous targeted inhibition of Sox2‐Oct4 transcription factors using decoy oligodeoxynucleotides to repress stemness properties in mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1002/cbin.10998openalex-snapshot
Ca2+‐depended signaling pathways regulate self‐renewal and pluripotency of stem cells
inferred← citeshttps://doi.org/10.1002/cbin.11153openalex-snapshot
Inhibition of transcription factor T‐cell factor 3 (TCF3) using the oligodeoxynucleotide strategy increases embryonic stem cell stemness: possible application in regenerative medicine
inferred← citeshttps://doi.org/10.1002/cbin.12168openalex-snapshot
A high‐throughput screen in mESCs to identify the cross‐talk between signaling, endocytosis, and pluripotency
inferred← citeshttps://doi.org/10.1002/cpsc.85openalex-snapshot
Generation of ERK‐Independent Human and Non‐Human Primate Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1002/cyto.a.24551openalex-snapshot
Timely stimulation of early embryo promotes the acquisition of pluripotency
inferred← citeshttps://doi.org/10.1002/dvdy.22447openalex-snapshot
Ectopic expression of GATA6 bypasses requirement for Grb2 in primitive endoderm formation
inferred← citeshttps://doi.org/10.1002/dvdy.23851openalex-snapshot
Ectopic expression of Fgf3 leads to aberrant lineage segregation in the mouse parthenote preimplantation embryos
inferred← citeshttps://doi.org/10.1002/dvdy.24261openalex-snapshot
SPREDs (Sprouty Related Proteins with EVH1 Domain) promote self‐renewal and inhibit mesodermal differentiation in murine embryonic stem cells
inferred← citeshttps://doi.org/10.1002/dvdy.24471openalex-snapshot
Signaling pathways in mammalian preimplantation development: Linking cellular phenotypes to lineage decisions
inferred← citeshttps://doi.org/10.1002/dvg.22368openalex-snapshot
Anatomy of a blastocyst: Cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo
inferred← citeshttps://doi.org/10.1002/dvg.22849openalex-snapshot
Derivation of chondrocyte and osteoblast reporter mouse embryonic stem cell lines
inferred← citeshttps://doi.org/10.1002/dvg.23470openalex-snapshot
Nhlrc2 is crucial during mouse gastrulation
inferred← citeshttps://doi.org/10.1002/embj.201387638openalex-snapshot
Shaking up the salt and pepper: origins of cellular heterogeneity in the inner cell mass of the blastocyst
inferred← citeshttps://doi.org/10.1002/emmm.201000065openalex-snapshot
Pluripotent stem cells: private obsession and public expectation
inferred← citeshttps://doi.org/10.1002/jcb.23244openalex-snapshot
Effect of dual‐specificity protein phosphatase 5 on pluripotency maintenance and differentiation of mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1002/jcp.28759openalex-snapshot
Effect of embryo cryopreservation on derivation efficiency, pluripotency, and differentiation capacity of mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1002/jnr.23687openalex-snapshot
Implications of mitogen‐activated protein kinase signaling in glioma
inferred← citeshttps://doi.org/10.1002/mrd.22346openalex-snapshot
Germ‐cell culture conditions facilitate the production of mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1002/mrd.22646openalex-snapshot
Conserved roles of fibroblast growth factor receptor 2 signaling in the regulation of inner cell mass development in bovine blastocysts
inferred← citeshttps://doi.org/10.1002/mrd.70002openalex-snapshot
Early Cell Lineage Formation in Mammals: Complexity, Species Diversity, and Susceptibility to Disruptions Impacting Embryo Viability
inferred← citeshttps://doi.org/10.1002/rmb2.70059openalex-snapshot
Dissecting Human Embryogenesis With Blastoids: Insights Into Lineage Specification and Early Development
inferred← citeshttps://doi.org/10.1002/stem.1018openalex-snapshot
Protein Kinase C Mediated Extraembryonic Endoderm Differentiation of Human Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1002/stem.1119openalex-snapshot
Dual Inhibition of Src and GSK3 Maintains Mouse Embryonic Stem Cells, Whose Differentiation Is Mechanically Regulated by Src Signaling
inferred← citeshttps://doi.org/10.1002/stem.1284openalex-snapshot
Transcription Elongation Factor Tcea3 Regulates the Pluripotent Differentiation Potential of Mouse Embryonic Stem Cells Via the Lefty1-Nodal-Smad2 Pathway
inferred← citeshttps://doi.org/10.1002/stem.1287openalex-snapshot
Concise Review: Bone Marrow Meets Blastocyst: Lessons from an Unlikely Encounter
inferred← citeshttps://doi.org/10.1002/stem.1323openalex-snapshot
Dynamic Migration and Cell-Cell Interactions of Early Reprogramming Revealed by High-Resolution Time-Lapse Imaging
inferred← citeshttps://doi.org/10.1002/stem.1442openalex-snapshot
PDGF signaling is required for primitive endoderm cell survival in the inner cell mass of the mouse blastocyst
inferred← citeshttps://doi.org/10.1002/stem.1889openalex-snapshot
Acute Loss of Cited2 Impairs Nanog Expression and Decreases Self-Renewal of Mouse Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1002/stem.1992openalex-snapshot
Single-Cell XIST Expression in Human Preimplantation Embryos and Newly Reprogrammed Female Induced Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1002/stem.2067openalex-snapshot
Dynamic Proteomic Profiling of Extra-Embryonic Endoderm Differentiation in Mouse Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1002/stem.2507openalex-snapshot
Concise Review: Lessons from Naïve Human Pluripotent Cells
inferred← citeshttps://doi.org/10.1002/stem.2647openalex-snapshot
Disrupting Interactions Between β-Catenin and Activating TCFs Reconstitutes Ground State Pluripotency in Mouse Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1002/stem.3008openalex-snapshot
PDGF Signaling in Primitive Endoderm Cell Survival Is Mediated by PI3K-mTOR Through p53-Independent Mechanism
inferred← citeshttps://doi.org/10.1002/stem.530openalex-snapshot
Neuronatin Promotes Neural Lineage in ESCs via Ca2+ Signaling
inferred← citeshttps://doi.org/10.1002/stem.712openalex-snapshot
The RNA-Binding Protein Unr Prevents Mouse Embryonic Stem Cells Differentiation Toward the Primitive Endoderm Lineage
inferred← citeshttps://doi.org/10.1002/wdev.220openalex-snapshot
The mammalian blastocyst
inferred← citeshttps://doi.org/10.1002/wdev.259openalex-snapshot
Properties of embryoid bodies
inferred← citeshttps://doi.org/10.1002/wdev.319openalex-snapshot
Making lineage decisions with biological noise: Lessons from the early mouse embryo
inferred← citeshttps://doi.org/10.1007/7651_2015_253openalex-snapshot
Maximizing Clonal Embryonic Stem Cell Derivation by ERK Pathway Inhibition
inferred← citeshttps://doi.org/10.1007/978-1-0716-1908-7_1openalex-snapshot
Deriving Human Naïve Embryonic Stem Cell Lines from Donated Supernumerary Embryos Using Physical Distancing and Signal Inhibition
inferred← citeshttps://doi.org/10.1007/978-1-4419-7037-4openalex-snapshot
The Cell Biology of Stem Cells
inferred← citeshttps://doi.org/10.1007/978-1-4419-7037-4_1openalex-snapshot
Early Embryonic Cell Fate Decisions in the Mouse
inferred← citeshttps://doi.org/10.1007/978-1-4614-1475-9_13openalex-snapshot
Induced Pluripotential Stem Cells and the Prospects for Cardiac Cell Therapy
inferred← citeshttps://doi.org/10.1007/978-1-61779-210-6_21openalex-snapshot
Derivation of Mouse Embryonic Stem Cell Lines from Blastocysts Produced by Fertilization and Somatic Cell Nuclear Transfer
inferred← citeshttps://doi.org/10.1007/978-3-319-63187-5_6openalex-snapshot
XEN and the Art of Stem Cell Maintenance: Molecular Mechanisms Maintaining Cell Fate and Self-Renewal in Extraembryonic Endoderm Stem (XEN) Cell Lines
inferred← citeshttps://doi.org/10.1007/978-3-642-20792-1_18openalex-snapshot
Derivation of Murine ES Cell Lines
inferred← citeshttps://doi.org/10.1007/978-3-642-30406-4_10openalex-snapshot
Cell Lineage Allocation Within the Inner Cell Mass of the Mouse Blastocyst
inferred← citeshttps://doi.org/10.1007/978-3-642-30406-4_11openalex-snapshot
Formation of Distinct Cell Types in the Mouse Blastocyst
inferred← citeshttps://doi.org/10.1007/978-3-642-30406-4_18openalex-snapshot
Mouse and Human Pluripotent Stem Cells and the Means of Their Myogenic Differentiation
inferred← citeshttps://doi.org/10.1007/978-94-007-2993-3_33openalex-snapshot
Somatic Cell Reprogramming: Role of Homeodomain Protein Nanog
inferred← citeshttps://doi.org/10.1007/978-94-007-4798-2_13openalex-snapshot
Reprogramming and Pluripotency of Epiblast Stem Cells
inferred← citeshttps://doi.org/10.1007/978-94-007-6621-1_17openalex-snapshot
Epigenetic Regulation of Stem Cells
inferred← citeshttps://doi.org/10.1007/s00018-012-0991-8openalex-snapshot
Current perspectives of the signaling pathways directing neural crest induction
inferred← citeshttps://doi.org/10.1007/s00018-014-1596-1openalex-snapshot
From pluripotency to forebrain patterning: an in vitro journey astride embryonic stem cells
inferred← citeshttps://doi.org/10.1007/s00018-014-1630-3openalex-snapshot
A close look at the mammalian blastocyst: epiblast and primitive endoderm formation
inferred← citeshttps://doi.org/10.1007/s00018-015-1833-2openalex-snapshot
Molecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency network
inferred← citeshttps://doi.org/10.1007/s00109-012-0912-1openalex-snapshot
The reciprocal relationship between primordial germ cells and pluripotent stem cells
inferred← citeshttps://doi.org/10.1007/s00285-023-01959-9openalex-snapshot
Adjusting the range of cell–cell communication enables fine-tuning of cell fate patterns from checkerboard to engulfing
inferred← citeshttps://doi.org/10.1007/s00412-012-0365-xopenalex-snapshot
Establishment of epigenetic patterns in development
inferred← citeshttps://doi.org/10.1007/s00441-021-03530-8openalex-snapshot
Cell fate determination and Hippo signaling pathway in preimplantation mouse embryo
inferred← citeshttps://doi.org/10.1007/s10735-024-10338-7openalex-snapshot
Signaling pathway regulators in preimplantation embryos
inferred← citeshttps://doi.org/10.1007/s10815-018-1360-9openalex-snapshot
Single blastomeres as a source of mouse embryonic stem cells: effect of genetic background, medium supplements, and signaling modulators on derivation efficiency
inferred← citeshttps://doi.org/10.1007/s11248-019-00168-9openalex-snapshot
Introducing gene deletions by mouse zygote electroporation of Cas12a/Cpf1
inferred← citeshttps://doi.org/10.1007/s11626-019-00341-8openalex-snapshot
The N-end rule pathway enzyme Naa10 supports epiblast specification in mouse embryonic stem cells by modulating FGF/MAPK
inferred← citeshttps://doi.org/10.1007/s12015-012-9382-7openalex-snapshot
Effect of Small Molecule Supplements during In Vitro Culture of Mouse Zygotes and Parthenogenetic Embryos on Hypoblast Formation and Stem Cell Derivation
inferred← citeshttps://doi.org/10.1007/s12015-015-9620-xopenalex-snapshot
Pluripotent Conversion of Muscle Stem Cells Without Reprogramming Factors or Small Molecules
inferred← citeshttps://doi.org/10.1007/s12015-017-9782-9openalex-snapshot
Noncoding RNAs in the Regulation of Pluripotency and Reprogramming
inferred← citeshttps://doi.org/10.1007/s12015-022-10441-wopenalex-snapshot
RBM47 is a Critical Regulator of Mouse Embryonic Stem Cell Differentiation
inferred← citeshttps://doi.org/10.1007/s12015-022-10490-1openalex-snapshot
Maternal Undernutrition Induces Cell Signalling and Metabolic Dysfunction in Undifferentiated Mouse Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1007/s12035-013-8532-5openalex-snapshot
Receptor Tyrosine Kinase (RTK) Signalling in the Control of Neural Stem and Progenitor Cell (NSPC) Development
inferred← citeshttps://doi.org/10.1007/s12522-014-0199-8openalex-snapshot
How are pluripotent cells captured in culture?
inferred← citeshttps://doi.org/10.1007/s13238-012-2920-xopenalex-snapshot
Delineating nuclear reprogramming
inferred← citeshttps://doi.org/10.1016/b978-0-12-386015-6.00022-6openalex-snapshot
Factors Regulating Pluripotency and Differentiation in Early Mammalian Embryos and Embryo-derived Stem Cells
inferred← citeshttps://doi.org/10.1016/b978-0-12-394304-0.00012-9openalex-snapshot
Mechanisms of Cardiogenesis in Cardiovascular Progenitor Cells
inferred← citeshttps://doi.org/10.1016/b978-0-12-416022-4.00001-9openalex-snapshot
Mechanisms of Pluripotency In Vivo and In Vitro
inferred← citeshttps://doi.org/10.1016/b978-0-12-813570-9.00005-xopenalex-snapshot
In Vitro Spermatogenesis From Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1016/b978-0-12-820071-1.00012-8openalex-snapshot
Signaling pathways influencing stem cell self-renewal and differentiation
inferred← citeshttps://doi.org/10.1016/b978-0-323-91380-5.00014-9openalex-snapshot
In vitro spermatogenesis from pluripotent stem cells
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2015.11.015openalex-snapshot
Making the Mouse Blastocyst
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2016.04.006openalex-snapshot
The Genetic Regulation of Cell Fate During Preimplantation Mouse Development
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2016.04.007openalex-snapshot
Capturing Identity and Fate Ex Vivo
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2017.10.010openalex-snapshot
The Regulative Nature of Mammalian Embryos
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2017.11.002openalex-snapshot
States and Origins of Mammalian Embryonic Pluripotency In Vivo and in a Dish
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2017.11.004openalex-snapshot
Human Pre-gastrulation Development
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2017.11.005openalex-snapshot
Pre-implantation Development of Domestic Animals
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2017.11.008openalex-snapshot
Capturing and Interconverting Embryonic Cell Fates in a Dish
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2017.12.001openalex-snapshot
Primitive Endoderm Differentiation: From Specification to Epithelialization
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2023.01.010openalex-snapshot
The role of Wnt signaling in the development of the epiblast and axial progenitors
inferred← citeshttps://doi.org/10.1016/j.advenzreg.2010.09.017openalex-snapshot
Deciphering the signaling pathways of cancer stem cells of glioblastoma multiforme: Role of Akt/mTOR and MAPK pathways
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2013.10.001openalex-snapshot
OCT4: Dynamic DNA binding pioneers stem cell pluripotency
inferred← citeshttps://doi.org/10.1016/j.bbih.2025.101020openalex-snapshot
Altered behaviour and immune response in mice with NHLRC2 p.Asp148Tyr variant
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.12.144openalex-snapshot
Characterization of goat inner cell mass derived cells in double kinase inhibition condition
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.01.037openalex-snapshot
ERK-independent African Green monkey pluripotent stem cells in a putative chimera-competent state
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.03.081openalex-snapshot
Inhibitory action of an ERK1/2 inhibitor on primitive endoderm cell differentiation from mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2022.02.002openalex-snapshot
An efficient method of inducing differentiation of mouse embryonic stem cells into primitive endodermal cells
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2017.12.014openalex-snapshot
VE-Cadherin regulates the self-renewal of mouse embryonic stem cells via LIF/Stat3 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.bpj.2015.12.020openalex-snapshot
Cell Fate Specification Based on Tristability in the Inner Cell Mass of Mouse Blastocysts
inferred← citeshttps://doi.org/10.1016/j.cbi.2019.108919openalex-snapshot
Modification of stem cell states by alcohol and acetaldehyde
inferred← citeshttps://doi.org/10.1016/j.ceb.2012.09.005openalex-snapshot
Signaling networks in human pluripotent stem cells
inferred← citeshttps://doi.org/10.1016/j.ceca.2016.01.005openalex-snapshot
Calcium signaling in human pluripotent stem cells
inferred← citeshttps://doi.org/10.1016/j.cell.2009.07.039openalex-snapshot
Nanog Is the Gateway to the Pluripotent Ground State
inferred← citeshttps://doi.org/10.1016/j.cell.2011.06.052openalex-snapshot
Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1016/j.cell.2012.04.002openalex-snapshot
Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1016/j.cell.2013.03.012openalex-snapshot
Exit from Pluripotency Is Gated by Intracellular Redistribution of the bHLH Transcription Factor Tfe3
inferred← citeshttps://doi.org/10.1016/j.cell.2025.07.018openalex-snapshot
A complete model of mouse embryogenesis through organogenesis enabled by chemically induced embryo founder cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2012.08.029openalex-snapshot
Developmental Plasticity Is Bound by Pluripotency and the Fgf and Wnt Signaling Pathways
inferred← citeshttps://doi.org/10.1016/j.celrep.2013.01.017openalex-snapshot
Tcf15 Primes Pluripotent Cells for Differentiation
inferred← citeshttps://doi.org/10.1016/j.celrep.2013.04.034openalex-snapshot
Totipotent Embryonic Stem Cells Arise in Ground-State Culture Conditions
inferred← citeshttps://doi.org/10.1016/j.celrep.2013.07.029openalex-snapshot
Conserved Regulation of the JAK/STAT Pathway by the Endosomal Protein Asrij Maintains Stem Cell Potency
inferred← citeshttps://doi.org/10.1016/j.celrep.2014.07.002openalex-snapshot
Genome-wide Functional Analysis Reveals Factors Needed at the Transition Steps of Induced Reprogramming
inferred← citeshttps://doi.org/10.1016/j.celrep.2014.11.032openalex-snapshot
Erk Signaling Suppresses Embryonic Stem Cell Self-Renewal to Specify Endoderm
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.02.010openalex-snapshot
Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.02.036openalex-snapshot
YAP Induces Human Naive Pluripotency
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.05.041openalex-snapshot
Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.07.009openalex-snapshot
Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.10.074openalex-snapshot
MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency State
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115238openalex-snapshot
Aurora B controls microtubule stability to regulate abscission dynamics in stem cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115506openalex-snapshot
STAT3 signaling enhances tissue expansion during postimplantation mouse development
inferred← citeshttps://doi.org/10.1016/j.cels.2023.07.008openalex-snapshot
A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation
inferred← citeshttps://doi.org/10.1016/j.coisb.2018.08.002openalex-snapshot
(De)constructing the blastocyst: Lessons in self-organization from the mouse
inferred← citeshttps://doi.org/10.1016/j.cub.2011.09.010openalex-snapshot
Blimp1 Expression Predicts Embryonic Stem Cell Development In Vitro
inferred← citeshttps://doi.org/10.1016/j.cub.2025.07.031openalex-snapshot
Live imaging endogenous transcription factor dynamics reveals mechanisms of epiblast and primitive endoderm fate segregation
inferred← citeshttps://doi.org/10.1016/j.devcel.2010.02.012openalex-snapshot
Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst
inferred← citeshttps://doi.org/10.1016/j.devcel.2010.07.014openalex-snapshot
An Early Developmental Role for miRNAs in the Maintenance of Extraembryonic Stem Cells in the Mouse Embryo
inferred← citeshttps://doi.org/10.1016/j.devcel.2011.10.019openalex-snapshot
Primitive Endoderm Differentiates via a Three-Step Mechanism Involving Nanog and RTK Signaling
inferred← citeshttps://doi.org/10.1016/j.devcel.2013.05.004openalex-snapshot
Oct4 Cell-Autonomously Promotes Primitive Endoderm Development in the Mouse Blastocyst
inferred← citeshttps://doi.org/10.1016/j.devcel.2014.04.011openalex-snapshot
GATA6 Levels Modulate Primitive Endoderm Cell Fate Choice and Timing in the Mouse Blastocyst
inferred← citeshttps://doi.org/10.1016/j.devcel.2015.10.011openalex-snapshot
Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis
inferred← citeshttps://doi.org/10.1016/j.devcel.2016.06.014openalex-snapshot
Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency
inferred← citeshttps://doi.org/10.1016/j.devcel.2017.05.003openalex-snapshot
Lineage Establishment and Progression within the Inner Cell Mass of the Mouse Blastocyst Requires FGFR1 and FGFR2
inferred← citeshttps://doi.org/10.1016/j.devcel.2017.05.004openalex-snapshot
Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency
inferred← citeshttps://doi.org/10.1016/j.devcel.2019.05.024openalex-snapshot
Epiblast Formation by TEAD-YAP-Dependent Expression of Pluripotency Factors and Competitive Elimination of Unspecified Cells
inferred← citeshttps://doi.org/10.1016/j.devcel.2019.05.032openalex-snapshot
Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.09.030openalex-snapshot
Live Visualization of ERK Activity in the Mouse Blastocyst Reveals Lineage-Specific Signaling Dynamics
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.11.017openalex-snapshot
Embryonic Stem Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK
inferred← citeshttps://doi.org/10.1016/j.devcel.2021.05.011openalex-snapshot
Tissue mechanics in stem cell fate, development, and cancer
inferred← citeshttps://doi.org/10.1016/j.devcel.2023.09.013openalex-snapshot
In vitro generation of mouse morula-like cells
inferred← citeshttps://doi.org/10.1016/j.devcel.2024.10.001openalex-snapshot
PI3K/AKT signaling controls ICM maturation and proper epiblast and primitive endoderm specification in mice
inferred← citeshttps://doi.org/10.1016/j.ejcb.2013.03.003openalex-snapshot
Dual effects of peroxisome proliferator-activated receptor γ on embryonic stem cell self-renewal in presence and absence of leukemia inhibitory factor
inferred← citeshttps://doi.org/10.1016/j.febslet.2010.09.016openalex-snapshot
SHP2 is a downstream target of ZAP70 to regulate JAK1/STAT3 and ERK signaling pathways in mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1016/j.febslet.2015.04.055openalex-snapshot
Architectural hallmarks of the pluripotent genome
inferred← citeshttps://doi.org/10.1016/j.gde.2010.05.006openalex-snapshot
Developmental control of the early mammalian embryo: competition among heterogeneous cells that biases cell fate
inferred← citeshttps://doi.org/10.1016/j.gde.2012.03.001openalex-snapshot
Accessing naïve human pluripotency
inferred← citeshttps://doi.org/10.1016/j.gde.2012.03.004openalex-snapshot
Mutual exclusion of transcription factors and cell behaviour in the definition of vertebrate embryonic territories
inferred← citeshttps://doi.org/10.1016/j.gde.2017.07.013openalex-snapshot
Signaling networks in the control of pluripotency
inferred← citeshttps://doi.org/10.1016/j.gde.2023.102088openalex-snapshot
Recent advances in stem cell-based blastocyst models
inferred← citeshttps://doi.org/10.1016/j.gde.2023.102115openalex-snapshot
In vitro models of human hypoblast and mouse primitive endoderm
inferred← citeshttps://doi.org/10.1016/j.gpb.2020.08.004openalex-snapshot
Npac Is a Co-Factor of Histone H3K36me3 and Regulates Transcriptional Elongation in Mouse Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1016/j.heliyon.2018.e00667openalex-snapshot
Single cell expression analysis of primate-specific retroviruses-derived HPAT lincRNAs in viable human blastocysts identifies embryonic cells co-expressing genetic markers of multiple lineages
inferred← citeshttps://doi.org/10.1016/j.isci.2023.108106openalex-snapshot
The salt-and-pepper pattern in mouse blastocysts is compatible with signaling beyond the nearest neighbors
inferred← citeshttps://doi.org/10.1016/j.jbior.2022.100946openalex-snapshot
Defining the role of mTOR pathway in the regulation of stem cells of glioblastoma
inferred← citeshttps://doi.org/10.1016/j.jbior.2025.101143openalex-snapshot
Complex role of mTOR signaling pathway in glioblastoma and its stem cells
inferred← citeshttps://doi.org/10.1016/j.jmb.2017.04.013openalex-snapshot
Protein Kinases in Pluripotency—Beyond the Usual Suspects
inferred← citeshttps://doi.org/10.1016/j.mod.2016.06.002openalex-snapshot
ESCs injected into the 8-cell stage mouse embryo modify pattern of cleavage and cell lineage specification
inferred← citeshttps://doi.org/10.1016/j.mod.2016.06.003openalex-snapshot
Regulation of amino acid transporters in pluripotent cell populations in the embryo and in culture; novel roles for sodium-coupled neutral amino acid transporters
inferred← citeshttps://doi.org/10.1016/j.molcel.2012.07.010openalex-snapshot
Protection against De Novo Methylation Is Instrumental in Maintaining Parent-of-Origin Methylation Inherited from the Gametes
inferred← citeshttps://doi.org/10.1016/j.molcel.2016.06.039openalex-snapshot
OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation
inferred← citeshttps://doi.org/10.1016/j.scr.2011.11.001openalex-snapshot
Self-organizing circuitry and emergent computation in mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1016/j.scr.2014.04.012openalex-snapshot
Development of FGF2-dependent pluripotent stem cells showing naive state characteristics from murine preimplantation inner cell mass
inferred← citeshttps://doi.org/10.1016/j.scr.2014.11.005openalex-snapshot
Transcriptome analysis of chicken ES, blastodermal and germ cells reveals that chick ES cells are equivalent to mouse ES cells rather than EpiSC
inferred← citeshttps://doi.org/10.1016/j.scr.2018.05.005openalex-snapshot
Metabolic plasticity during transition to naïve-like pluripotency in canine embryo-derived stem cells
inferred← citeshttps://doi.org/10.1016/j.scr.2018.05.008openalex-snapshot
Isolation of primitive mouse extraembryonic endoderm (pXEN) stem cell lines
inferred← citeshttps://doi.org/10.1016/j.scr.2018.07.005openalex-snapshot
Distinct requirements for the maintenance and establishment of mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1016/j.semcdb.2014.09.012openalex-snapshot
Protein tyrosine phosphatase regulation of stem and progenitor cell biology
inferred← citeshttps://doi.org/10.1016/j.semcdb.2015.06.004openalex-snapshot
Single cells get together: High-resolution approaches to study the dynamics of early mouse development
inferred← citeshttps://doi.org/10.1016/j.stem.2010.03.015openalex-snapshot
Tracing the Derivation of Embryonic Stem Cells from the Inner Cell Mass by Single-Cell RNA-Seq Analysis
inferred← citeshttps://doi.org/10.1016/j.stem.2010.11.027openalex-snapshot
Calcineurin-NFAT Signaling Critically Regulates Early Lineage Specification in Mouse Embryonic Stem Cells and Embryos
inferred← citeshttps://doi.org/10.1016/j.stem.2012.02.020openalex-snapshot
NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment
inferred← citeshttps://doi.org/10.1016/j.stem.2012.02.023openalex-snapshot
The Germ Cell Determinant Blimp1 Is Not Required for Derivation of Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1016/j.stem.2013.04.023openalex-snapshot
Reduced Oct4 Expression Directs a Robust Pluripotent State with Distinct Signaling Activity and Increased Enhancer Occupancy by Oct4 and Nanog
inferred← citeshttps://doi.org/10.1016/j.stem.2014.01.021openalex-snapshot
Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming
inferred← citeshttps://doi.org/10.1016/j.stem.2014.03.001openalex-snapshot
Kinome-wide Functional Analysis Highlights the Role of Cytoskeletal Remodeling in Somatic Cell Reprogramming
inferred← citeshttps://doi.org/10.1016/j.stem.2014.04.015openalex-snapshot
Klf2 Is an Essential Factor that Sustains Ground State Pluripotency
inferred← citeshttps://doi.org/10.1016/j.stem.2016.12.004openalex-snapshot
New Insights into Early Human Development: Lessons for Stem Cell Derivation and Differentiation
inferred← citeshttps://doi.org/10.1016/j.stem.2019.07.009openalex-snapshot
Distinct Molecular Trajectories Converge to Induce Naive Pluripotency
inferred← citeshttps://doi.org/10.1016/j.stem.2020.07.005openalex-snapshot
Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency
inferred← citeshttps://doi.org/10.1016/j.stem.2020.10.018openalex-snapshot
Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate
inferred← citeshttps://doi.org/10.1016/j.stem.2021.01.008openalex-snapshot
Membrane Tension Locks In Pluripotency
inferred← citeshttps://doi.org/10.1016/j.stem.2022.06.003openalex-snapshot
Cell competition and the regulative nature of early mammalian development
inferred← citeshttps://doi.org/10.1016/j.stem.2024.01.009openalex-snapshot
Hallmarks of totipotent and pluripotent stem cell states
inferred← citeshttps://doi.org/10.1016/j.stem.2024.05.003openalex-snapshot
Naive pluripotent stem cell-based models capture FGF-dependent human hypoblast lineage specification
inferred← citeshttps://doi.org/10.1016/j.stem.2024.06.010openalex-snapshot
Unraveling the function of FGF signaling in human hypoblast specialization
inferred← citeshttps://doi.org/10.1016/j.stemcr.2013.07.003openalex-snapshot
Robust Self-Renewal of Rat Embryonic Stem Cells Requires Fine-Tuning of Glycogen Synthase Kinase-3 Inhibition
inferred← citeshttps://doi.org/10.1016/j.stemcr.2015.11.012openalex-snapshot
BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1016/j.stemcr.2016.02.003openalex-snapshot
OSKM Induce Extraembryonic Endoderm Stem Cells in Parallel to Induced Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1016/j.stemcr.2016.02.005openalex-snapshot
Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass
inferred← citeshttps://doi.org/10.1016/j.stemcr.2016.07.009openalex-snapshot
Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency
inferred← citeshttps://doi.org/10.1016/j.stemcr.2016.09.012openalex-snapshot
Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency
inferred← citeshttps://doi.org/10.1016/j.stemcr.2017.09.019openalex-snapshot
Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells
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