On the public citation graph

Inflammasome activation and assembly at a glance

https://doi.org/10.1242/jcs.207365

0 signed · 613 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1521-4141(200205)32:5<1464::aid-immu1464>3.0.co;2-gopenalex-snapshot

Cytotoxicity and interleukin-1β processing following Shigella flexneri infection of human monocyte-derived dendritic cells

inferredcites →https://doi.org/10.1002/eji.201040425openalex-snapshot

Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome

inferredcites →https://doi.org/10.1002/eji.201545523openalex-snapshot

Caspase‐4 mediates non‐canonical activation of the NLRP3 inflammasome in human myeloid cells

inferredcites →https://doi.org/10.1002/eji.201545655openalex-snapshot

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5

inferredcites →https://doi.org/10.1002/eji.201545772openalex-snapshot

Caspase‐11 activates a canonical NLRP3 inflammasome by promoting K + efflux

inferredcites →https://doi.org/10.1002/humu.20080openalex-snapshot

Infevers: An evolving mutation database for auto-inflammatory syndromes

inferredcites →https://doi.org/10.1002/ijc.28891openalex-snapshot

Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patients

inferredcites →https://doi.org/10.1002/prot.24287openalex-snapshot

Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase‐1

inferredcites →https://doi.org/10.1016/j.ajpath.2016.10.015openalex-snapshot

IL-1β and Caspase-1 Drive Autoinflammatory Disease Independently of IL-1α or Caspase-8 in a Mouse Model of Familial Mediterranean Fever

inferredcites →https://doi.org/10.1016/j.cell.2011.04.022openalex-snapshot

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

inferredcites →https://doi.org/10.1016/j.cell.2012.07.007openalex-snapshot

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

inferredcites →https://doi.org/10.1016/j.cell.2014.01.063openalex-snapshot

Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation

inferredcites →https://doi.org/10.1016/j.cell.2014.02.008openalex-snapshot

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

inferredcites →https://doi.org/10.1016/j.cell.2014.11.047openalex-snapshot

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

inferredcites →https://doi.org/10.1016/j.cell.2015.06.001openalex-snapshot

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

inferredcites →https://doi.org/10.1016/j.cell.2016.04.015openalex-snapshot

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation

inferredcites →https://doi.org/10.1016/j.cell.2016.09.012openalex-snapshot

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

inferredcites →https://doi.org/10.1016/j.celrep.2013.06.024openalex-snapshot

Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation

inferredcites →https://doi.org/10.1016/j.celrep.2014.05.008openalex-snapshot

XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation

inferredcites →https://doi.org/10.1016/j.celrep.2014.06.028openalex-snapshot

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

inferredcites →https://doi.org/10.1016/j.chom.2010.11.007openalex-snapshot

Differential Requirement for Caspase-1 Autoproteolysis in Pathogen-Induced Cell Death and Cytokine Processing

inferredcites →https://doi.org/10.1016/j.chom.2014.07.001openalex-snapshot

Epithelium-Intrinsic NAIP/NLRC4 Inflammasome Drives Infected Enterocyte Expulsion to Restrict Salmonella Replication in the Intestinal Mucosa

inferredcites →https://doi.org/10.1016/j.imlet.2012.07.003openalex-snapshot

Interferon-inducible Ifi200-family genes as modifiers of lupus susceptibility

inferredcites →https://doi.org/10.1016/j.immuni.2007.10.002openalex-snapshot

Intracellular NOD-like Receptors in Host Defense and Disease

inferredcites →https://doi.org/10.1016/j.immuni.2009.04.012openalex-snapshot

A Mutation in the Nlrp3 Gene Causing Inflammasome Hyperactivation Potentiates Th17 Cell-Dominant Immune Responses

inferredcites →https://doi.org/10.1016/j.immuni.2009.05.005openalex-snapshot

Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity

inferredcites →https://doi.org/10.1016/j.immuni.2011.02.020openalex-snapshot

Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice

inferredcites →https://doi.org/10.1016/j.immuni.2012.02.014openalex-snapshot

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

inferredcites →https://doi.org/10.1016/j.immuni.2012.06.013openalex-snapshot

Cell Volume Regulation Modulates NLRP3 Inflammasome Activation

inferredcites →https://doi.org/10.1016/j.immuni.2012.07.006openalex-snapshot

The NLRP12 Inflammasome Recognizes Yersinia pestis

inferredcites →https://doi.org/10.1016/j.immuni.2012.08.027openalex-snapshot

NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells

inferredcites →https://doi.org/10.1016/j.immuni.2013.05.016openalex-snapshot

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

inferredcites →https://doi.org/10.1016/j.immuni.2015.10.009openalex-snapshot

Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock

inferredcites →https://doi.org/10.1016/j.immuni.2016.01.012openalex-snapshot

Human Monocytes Engage an Alternative Inflammasome Pathway

inferredcites →https://doi.org/10.1016/j.immuni.2017.07.011openalex-snapshot

Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition

inferredcites →https://doi.org/10.1016/j.molcel.2012.11.009openalex-snapshot

Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity

inferredcites →https://doi.org/10.1016/j.molcel.2014.02.018openalex-snapshot

Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes

inferredcites →https://doi.org/10.1016/j.str.2015.10.001openalex-snapshot

Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR Activation

inferredcites →https://doi.org/10.1016/s0092-8674(00)80943-5openalex-snapshot

Murine Caspase-11, an ICE-Interacting Protease, Is Essential for the Activation of ICE

inferredcites →https://doi.org/10.1016/s1097-2765(02)00599-3openalex-snapshot

The Inflammasome

inferredcites →https://doi.org/10.1038/cr.2015.139openalex-snapshot

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

inferredcites →https://doi.org/10.1038/nature02664openalex-snapshot

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

inferredcites →https://doi.org/10.1038/nature04517openalex-snapshot

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

inferredcites →https://doi.org/10.1038/nature07710openalex-snapshot

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

inferredcites →https://doi.org/10.1038/nature07725openalex-snapshot

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

inferredcites →https://doi.org/10.1038/nature09663openalex-snapshot

A role for mitochondria in NLRP3 inflammasome activation

inferredcites →https://doi.org/10.1038/nature10394openalex-snapshot

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

inferredcites →https://doi.org/10.1038/nature10510openalex-snapshot

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

inferredcites →https://doi.org/10.1038/nature10558openalex-snapshot

Non-canonical inflammasome activation targets caspase-11

inferredcites →https://doi.org/10.1038/nature11250openalex-snapshot

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

inferredcites →https://doi.org/10.1038/nature11290openalex-snapshot

Novel role of PKR in inflammasome activation and HMGB1 release

inferredcites →https://doi.org/10.1038/nature11351openalex-snapshot

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

inferredcites →https://doi.org/10.1038/nature13449openalex-snapshot

Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

inferredcites →https://doi.org/10.1038/nature13683openalex-snapshot

Inflammatory caspases are innate immune receptors for intracellular LPS

inferredcites →https://doi.org/10.1038/nature13788openalex-snapshot

Dietary modulation of the microbiome affects autoinflammatory disease

inferredcites →https://doi.org/10.1038/nature15514openalex-snapshot

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

inferredcites →https://doi.org/10.1038/nature15541openalex-snapshot

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

inferredcites →https://doi.org/10.1038/nature16959openalex-snapshot

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

inferredcites →https://doi.org/10.1038/nature18590openalex-snapshot

Pore-forming activity and structural autoinhibition of the gasdermin family

inferredcites →https://doi.org/10.1038/nature18629openalex-snapshot

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

inferredcites →https://doi.org/10.1038/nature22393openalex-snapshot

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

inferredcites →https://doi.org/10.1038/nature22967openalex-snapshot

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

inferredcites →https://doi.org/10.1038/ncomms4209openalex-snapshot

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation

inferredcites →https://doi.org/10.1038/ng.3066openalex-snapshot

Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

inferredcites →https://doi.org/10.1038/ng.3089openalex-snapshot

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

inferredcites →https://doi.org/10.1038/ng1724openalex-snapshot

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

inferredcites →https://doi.org/10.1038/ng756openalex-snapshot

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome

inferredcites →https://doi.org/10.1038/ni.1631openalex-snapshot

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

inferredcites →https://doi.org/10.1038/ni.1636openalex-snapshot

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

inferredcites →https://doi.org/10.1038/ni.1702openalex-snapshot

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

inferredcites →https://doi.org/10.1038/ni.1859openalex-snapshot

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

inferredcites →https://doi.org/10.1038/ni.1864openalex-snapshot

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

inferredcites →https://doi.org/10.1038/ni.1960openalex-snapshot

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

inferredcites →https://doi.org/10.1038/ni.2222openalex-snapshot

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

inferredcites →https://doi.org/10.1038/ni.2550openalex-snapshot

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

inferredcites →https://doi.org/10.1038/ni.2749openalex-snapshot

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity

inferredcites →https://doi.org/10.1038/ni.2829openalex-snapshot

The PYRIN domain–only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses

inferredcites →https://doi.org/10.1038/ni.3118openalex-snapshot

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

inferredcites →https://doi.org/10.1038/ni.3119openalex-snapshot

Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida

inferredcites →https://doi.org/10.1038/ni.3333openalex-snapshot

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

inferredcites →https://doi.org/10.1038/ni.3457openalex-snapshot

Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS

inferredcites →https://doi.org/10.1038/ni.3487openalex-snapshot

Control of the innate immune response by the mevalonate pathway

inferredcites →https://doi.org/10.1038/ni.3538openalex-snapshot

NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations

inferredcites →https://doi.org/10.1038/ni1344openalex-snapshot

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf

inferredcites →https://doi.org/10.1038/ni1346openalex-snapshot

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

inferredcites →https://doi.org/10.1038/nm.3908openalex-snapshot

Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt

inferredcites →https://doi.org/10.1038/sj.cdd.4402195openalex-snapshot

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

inferredcites →https://doi.org/10.1073/pnas.0707370105openalex-snapshot

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

inferredcites →https://doi.org/10.1073/pnas.0803933105openalex-snapshot

The Nalp3 inflammasome is essential for the development of silicosis

inferredcites →https://doi.org/10.1073/pnas.0913087107openalex-snapshot

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

inferredcites →https://doi.org/10.1073/pnas.1003738107openalex-snapshot

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

inferredcites →https://doi.org/10.1073/pnas.1306376110openalex-snapshot

Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation

inferredcites →https://doi.org/10.1073/pnas.1320294111openalex-snapshot

IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation

inferredcites →https://doi.org/10.1073/pnas.1321700111openalex-snapshot

Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS

inferredcites →https://doi.org/10.1073/pnas.1415756111openalex-snapshot

Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function

inferredcites →https://doi.org/10.1073/pnas.1507579112openalex-snapshot

Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy

inferredcites →https://doi.org/10.1073/pnas.1601636113openalex-snapshot

NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β–mediated osteomyelitis

inferredcites →https://doi.org/10.1073/pnas.1601700113openalex-snapshot

Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activation

inferredcites →https://doi.org/10.1073/pnas.1607769113openalex-snapshot

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

inferredcites →https://doi.org/10.1073/pnas.1613156113openalex-snapshot

Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation

inferredcites →https://doi.org/10.1074/jbc.c100250200openalex-snapshot

Identification of Ipaf, a Human Caspase-1-activating Protein Related to Apaf-1

inferredcites →https://doi.org/10.1074/jbc.c115.700492openalex-snapshot

A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation

inferredcites →https://doi.org/10.1074/jbc.m110.139048openalex-snapshot

Sodium Overload and Water Influx Activate the NALP3 Inflammasome

inferredcites →https://doi.org/10.1074/jbc.m112.378323openalex-snapshot

Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity

inferredcites →https://doi.org/10.1074/jbc.m112.401406openalex-snapshot

Toll or Interleukin-1 Receptor (TIR) Domain-containing Adaptor Inducing Interferon-β (TRIF)-mediated Caspase-11 Protease Production Integrates Toll-like Receptor 4 (TLR4) Protein- and Nlrp3 Inflammasome-mediated Host Defense against Enteropathogens

inferredcites →https://doi.org/10.1074/jbc.m113.468033openalex-snapshot

Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly

inferredcites →https://doi.org/10.1074/jbc.m115.645549openalex-snapshot

Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase

inferredcites →https://doi.org/10.1074/jbc.m606721200openalex-snapshot

Essential Role for Caspase-8 in Toll-like Receptors and NFκB Signaling

inferredcites →https://doi.org/10.1074/jbc.m607594200openalex-snapshot

Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA

inferredcites →https://doi.org/10.1074/jbc.m608083200openalex-snapshot

ATP Activates a Reactive Oxygen Species-dependent Oxidative Stress Response and Secretion of Proinflammatory Cytokines in Macrophages

inferredcites →https://doi.org/10.1084/jem.20051659openalex-snapshot

Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

inferredcites →https://doi.org/10.1084/jem.20071632openalex-snapshot

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8

inferredcites →https://doi.org/10.1084/jem.20132486openalex-snapshot

The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation

inferredcites →https://doi.org/10.1084/jem.20141091openalex-snapshot

An inherited mutation in NLRC4 causes autoinflammation in human and mice

inferredcites →https://doi.org/10.1084/jem.20142384openalex-snapshot

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β

inferredcites →https://doi.org/10.1084/jem.20160933openalex-snapshot

NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain

inferredcites →https://doi.org/10.1086/340786openalex-snapshot

New Mutations of CIAS1 That Are Responsible for Muckle-Wells Syndrome and Familial Cold Urticaria: A Novel Mutation Underlies Both Syndromes

inferredcites →https://doi.org/10.1086/341357openalex-snapshot

Chronic Infantile Neurological Cutaneous and Articular Syndrome Is Caused by Mutations in CIAS1, a Gene Highly Expressed in Polymorphonuclear Cells and Chondrocytes

inferredcites →https://doi.org/10.1089/jir.2009.0096openalex-snapshot

Interferon-Inducible p200-Family Proteins as Novel Sensors of Cytoplasmic DNA: Role in Inflammation and Autoimmunity

inferredcites →https://doi.org/10.1093/hmg/7.8.1317openalex-snapshot

Non-founder mutations in the MEFV gene establish this gene as the cause of familial Mediterranean fever (FMF)

inferredcites →https://doi.org/10.1101/gr.10.8.1095openalex-snapshot

Genomic Sequence Analysis of the Mouse Naip Gene Array

inferredcites →https://doi.org/10.1107/s2053230x1303135xopenalex-snapshot

Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling

inferredcites →https://doi.org/10.1111/imr.12282openalex-snapshot

CARD ‐ and pyrin‐only proteins regulating inflammasome activation and immunity

inferredcites →https://doi.org/10.1111/j.1462-5822.2006.00751.xopenalex-snapshot

Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

inferredcites →https://doi.org/10.1126/science.1156995openalex-snapshot

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

inferredcites →https://doi.org/10.1126/science.1169841openalex-snapshot

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

inferredcites →https://doi.org/10.1126/science.1230751openalex-snapshot

Caspase-11 Protects Against Bacteria That Escape the Vacuole

inferredcites →https://doi.org/10.1126/science.1240248openalex-snapshot

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

inferredcites →https://doi.org/10.1126/science.1240988openalex-snapshot

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

inferredcites →https://doi.org/10.1126/science.aac5489openalex-snapshot

Structural and biochemical basis for induced self-propagation of NLRC4

inferredcites →https://doi.org/10.1126/science.aac5789openalex-snapshot

Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization

inferredcites →https://doi.org/10.1126/scitranslmed.3002001openalex-snapshot

Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions

inferredcites →https://doi.org/10.1126/scitranslmed.aaf1471openalex-snapshot

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation

inferredcites →https://doi.org/10.1128/iai.00898-10openalex-snapshot

NALP1 Influences Susceptibility to Human Congenital Toxoplasmosis, Proinflammatory Cytokine Response, and Fate ofToxoplasma gondii-Infected Monocytic Cells

inferredcites →https://doi.org/10.1128/iai.01032-08openalex-snapshot

Anthrax Lethal Toxin Triggers the Formation of a Membrane-Associated Inflammasome Complex in Murine Macrophages

inferredcites →https://doi.org/10.1128/iai.01170-13openalex-snapshot

NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii

inferredcites →https://doi.org/10.1128/mbio.01117-13openalex-snapshot

Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii

inferredcites →https://doi.org/10.1158/1541-7786.mcr-13-0145openalex-snapshot

AIM2, an IFN-Inducible Cytosolic DNA Sensor, in the Development of Benign Prostate Hyperplasia and Prostate Cancer

inferredcites →https://doi.org/10.1172/jci71543openalex-snapshot

Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies

inferredcites →https://doi.org/10.1182/blood-2003-07-2531openalex-snapshot

Molecular basis of the spectral expression of CIAS1 mutations associated with phagocytic cell-mediated autoinflammatory disorders CINCA/NOMID, MWS, and FCU

inferredcites →https://doi.org/10.1182/blood-2010-08-303115openalex-snapshot

Tumor suppressor death-associated protein kinase is required for full IL-1β production

inferredcites →https://doi.org/10.1186/1471-2148-12-140openalex-snapshot

The mammalian PYHIN gene family: Phylogeny, evolution and expression

inferredcites →https://doi.org/10.1189/jlb.3hi0814-371rropenalex-snapshot

Syk is involved in NLRP3 inflammasome-mediated caspase-1 activation through adaptor ASC phosphorylation and enhanced oligomerization

inferredcites →https://doi.org/10.1371/journal.ppat.0020018openalex-snapshot

Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity

inferredcites →https://doi.org/10.1371/journal.ppat.1001222openalex-snapshot

Inflammasome Sensor Nlrp1b-Dependent Resistance to Anthrax Is Mediated by Caspase-1, IL-1 Signaling and Neutrophil Recruitment

inferredcites →https://doi.org/10.1371/journal.ppat.1002659openalex-snapshot

Proteolytic Processing of Nlrp1b Is Required for Inflammasome Activity

inferredcites →https://doi.org/10.1371/journal.ppat.1003452openalex-snapshot

Direct Proteolytic Cleavage of NLRP1B Is Necessary and Sufficient for Inflammasome Activation by Anthrax Lethal Factor

inferredcites →https://doi.org/10.1371/journal.ppat.1004005openalex-snapshot

A Highly Conserved Toxo1 Haplotype Directs Resistance to Toxoplasmosis and Its Associated Caspase-1 Dependent Killing of Parasite and Host Macrophage

inferredcites →https://doi.org/10.1371/journal.ppat.1004150openalex-snapshot

The Inflammasome Pyrin Contributes to Pertussis Toxin-Induced IL-1β Synthesis, Neutrophil Intravascular Crawling and Autoimmune Encephalomyelitis

inferredcites →https://doi.org/10.15252/embj.201694696openalex-snapshot

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

inferredcites →https://doi.org/10.2119/molmed.2013.00162openalex-snapshot

Increased Expression and Activation of Absent in Melanoma 2 Inflammasome Components in Lymphocytic Infiltrates of Abdominal Aortic Aneurysms

inferredcites →https://doi.org/10.4049/jimmunol.0903114openalex-snapshot

Cutting Edge: Resistance to Bacillus anthracis Infection Mediated by a Lethal Toxin Sensitive Allele of Nalp1b/Nlrp1b

inferredcites →https://doi.org/10.4049/jimmunol.1102272openalex-snapshot

Activation of the Pyrin Inflammasome by Intracellular Burkholderia cenocepacia

inferredcites →https://doi.org/10.4049/jimmunol.1301549openalex-snapshot

Cutting Edge: Mouse NAIP1 Detects the Type III Secretion System Needle Protein

inferredcites →https://doi.org/10.4049/jimmunol.1301681openalex-snapshot

Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome

inferredcites →https://doi.org/10.4049/jimmunol.1302839openalex-snapshot

FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes

inferredcites →https://doi.org/10.4049/jimmunol.1403100openalex-snapshot

Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin

inferredcites →https://doi.org/10.4049/jimmunol.1502538openalex-snapshot

Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA

inferredcites →https://doi.org/10.4049/jimmunol.169.8.4088openalex-snapshot

Cutting Edge: CATERPILLER: A Large Family of Mammalian Genes Containing CARD, Pyrin, Nucleotide-Binding, and Leucine-Rich Repeat Domains

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4673402openalex-extracted

Shengxian Decoction Protects Against Obesity-Induced Cardiac Injuryin Rats by Regulating the Hk1/Nlrp3 Signalling Pathway

inferred← citeshttps://doi.org/10.1002/advs.202204900openalex-snapshot

Nanoreporter for Real‐Time Monitoring of Inflammasome Activity and Targeted Therapy

inferred← citeshttps://doi.org/10.1002/ame2.12361openalex-snapshot

Microglial ApoD ‐induced NLRC4 inflammasome activation promotes Alzheimer's disease progression

inferred← citeshttps://doi.org/10.1002/cbdv.202301628openalex-snapshot

Two New Prostaglandin‐Like Compounds from Callicarpa arborea Roxb and Their NLRP3 Inflammasome Activation Inhibitory Activity

inferred← citeshttps://doi.org/10.1002/ctm2.849openalex-snapshot

Hepatic pannexin‐1 mediates ST2+ regulatory T cells promoting resolution of inflammation in lipopolysaccharide‐induced endotoxemia

inferred← citeshttps://doi.org/10.1002/eji.202250266openalex-snapshot

The innate immune response in tauopathies

inferred← citeshttps://doi.org/10.1002/glia.23896openalex-snapshot

Intranasal anti‐caspase‐1 therapy preserves myelin and glucose metabolism in a model of progressive multiple sclerosis

inferred← citeshttps://doi.org/10.1002/iid3.1062openalex-snapshot

Regulation of cell proliferation and transdifferentiation compensates for ventilator‐induced lung injury mediated by NLRP3 inflammasome activation

inferred← citeshttps://doi.org/10.1002/iid3.70213openalex-snapshot

Molecular Mechanism of NLRP3 Inflammasome in Inflammatory Diseases and Tumors

inferred← citeshttps://doi.org/10.1002/iid3.750openalex-snapshot

The role of the NLRP3 inflammasome in chronic inflammation in asthma and chronic obstructive pulmonary disease

inferred← citeshttps://doi.org/10.1002/jbt.23592openalex-snapshot

Inhibition of NLRP3 inflammasome—A potential mechanistic therapeutic for treatment of polycystic ovary syndrome?

inferred← citeshttps://doi.org/10.1002/jlb.3mir0917-350ropenalex-snapshot

An update on cell intrinsic negative regulators of the NLRP3 inflammasome

inferred← citeshttps://doi.org/10.1002/jlb.3mr0720-472rropenalex-snapshot

The role of the microbiome and the NLRP3 inflammasome in the gut and lung

inferred← citeshttps://doi.org/10.1002/kjm2.70273openalex-snapshot

NETosis in the Kidney, Liver, and Lung of Mice With Cecal Ligation and Puncture‐Induced Sepsis and the Ameliorating Effects of Adipose‐Derived Stem Cell Exosomes

inferred← citeshttps://doi.org/10.1002/mco2.70844openalex-snapshot

The Multifaceted Role of Pyroptosis: Molecular Mechanisms, Crosstalk with Other Cell Death Pathways, and Therapeutic Implications

inferred← citeshttps://doi.org/10.1002/mnfr.201801230openalex-snapshot

Epigallocatechin‐3‐Gallate Attenuates Microglial Inflammation and Neurotoxicity by Suppressing the Activation of Canonical and Noncanonical Inflammasome via TLR4/NF‐κB Pathway

inferred← citeshttps://doi.org/10.1007/978-1-0716-2553-8_15openalex-snapshot

Simultaneous Detection of Inflammasome Activation and Membrane Damage During Pyroptosis

inferred← citeshttps://doi.org/10.1007/978-3-030-68748-9_17openalex-snapshot

Redox and Inflammatory Signaling, the Unfolded Protein Response, and the Pathogenesis of Pulmonary Hypertension

inferred← citeshttps://doi.org/10.1007/978-3-031-25879-4_2openalex-snapshot

Pathogenesis of Atherosclerosis: A Multifactorial Process

inferred← citeshttps://doi.org/10.1007/978-3-031-26322-4_4openalex-snapshot

Alimentation, Bacterial Metabolites, and Host Intestinal Epithelium

inferred← citeshttps://doi.org/10.1007/978-3-031-26945-5_15openalex-snapshot

Acupuncture for Counteracting P2X4 and P2X7 Receptor Involvement in Neuroinflammation

inferred← citeshttps://doi.org/10.1007/978-981-19-8342-9_1openalex-snapshot

Cardioimmunology: An Interdisciplinary Approach

inferred← citeshttps://doi.org/10.1007/978-981-97-7905-5_10openalex-snapshot

Mechanisms of PANoptosis and Its Implications in Cancer Progression and Treatment

inferred← citeshttps://doi.org/10.1007/s00018-021-04072-6openalex-snapshot

DExD/H-box helicases: multifunctional regulators in antiviral innate immunity

inferred← citeshttps://doi.org/10.1007/s00018-022-04211-7openalex-snapshot

ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system

inferred← citeshttps://doi.org/10.1007/s00018-026-06185-2openalex-snapshot

TRPV4 is involved in NLRP3 and NLRP1 inflammasomes activation after pilocarpine-induced status epilepticus in mice

inferred← citeshttps://doi.org/10.1007/s00044-020-02692-4openalex-snapshot

Structural insights of sulfonamide-based NLRP3 inflammasome inhibitors: design, synthesis, and biological characterization

inferred← citeshttps://doi.org/10.1007/s00210-024-02994-zopenalex-snapshot

A current review on P2X7 receptor antagonist patents in the treatment of neuroinflammatory disorders: a patent review on antagonists

inferred← citeshttps://doi.org/10.1007/s00210-024-03261-xopenalex-snapshot

RETRACTED ARTICLE: Betaine alleviates doxorubicin-related cardiotoxicity via suppressing oxidative stress and inflammation via the NLRP3/SIRT1 pathway

inferred← citeshttps://doi.org/10.1007/s00411-018-0768-zopenalex-snapshot

Temporarily increased TGFβ following radon spa correlates with reduced pain while serum IL-18 is a general predictive marker for pain sensitivity

inferred← citeshttps://doi.org/10.1007/s10495-021-01682-0openalex-snapshot

Programmed cell death, redox imbalance, and cancer therapeutics

inferred← citeshttps://doi.org/10.1007/s10495-025-02089-xopenalex-snapshot

PANoptosis: a potential target of atherosclerotic cardiovascular disease

inferred← citeshttps://doi.org/10.1007/s10753-020-01301-1openalex-snapshot

Understanding the Role of Inflammasomes in Rheumatoid Arthritis

inferred← citeshttps://doi.org/10.1007/s10787-020-00691-wopenalex-snapshot

Pharmacological inhibition of soluble epoxide hydrolase attenuates chronic experimental autoimmune encephalomyelitis by modulating inflammatory and anti-inflammatory pathways in an inflammasome-dependent and -independent manner

inferred← citeshttps://doi.org/10.1007/s11010-022-04602-1openalex-snapshot

The role of Nod-like receptor protein 3 inflammasome activated by ion channels in multiple diseases

inferred← citeshttps://doi.org/10.1007/s11010-024-05147-1openalex-snapshot

Unveiling the nexus: pyroptosis and its crucial implications in liver diseases

inferred← citeshttps://doi.org/10.1007/s11064-020-03109-9openalex-snapshot

Ibuprofen Exerts Antiepileptic and Neuroprotective Effects in the Rat Model of Pentylenetetrazol-Induced Epilepsy via the COX-2/NLRP3/IL-18 Pathway

inferred← citeshttps://doi.org/10.1007/s11259-024-10505-xopenalex-snapshot

Mycobacterium intracellulare mediates macrophage pyroptosis by activating AIM2 and NLRP3 inflammasomes

inferred← citeshttps://doi.org/10.1007/s12013-025-01912-1openalex-snapshot

PANoptosis: Molecular Mechanisms, Regulatory Pathways, and Implications in Disease Pathogenesis

inferred← citeshttps://doi.org/10.1007/s12026-022-09285-wopenalex-snapshot

Cytokine storm and targeted therapy in hemophagocytic lymphohistiocytosis

inferred← citeshttps://doi.org/10.1007/s12035-025-04975-6openalex-snapshot

Upregulation of NLRP3 Inflammasome in Specific Hippocampal Regions: Strengthening the Link Between Neuroinflammation and Selective Vulnerability in Alzheimer’s Disease

inferred← citeshttps://doi.org/10.1007/s12094-023-03241-2openalex-snapshot

Cervical carcinoma induces NLRP3 inflammasome activation and IL-1ß release in human peripheral blood monocytes affecting patients’ overall survival

inferred← citeshttps://doi.org/10.1007/s12264-023-01034-9openalex-snapshot

Glia Connect Inflammation and Neurodegeneration in Multiple Sclerosis

inferred← citeshttps://doi.org/10.1007/s12640-026-00791-5openalex-snapshot

Tubuloside B Alleviates Aβ25-35 Induced PC12 Cell Injury by Attenuating Pyroptosis, Apoptosis and Excessive Autophagy

inferred← citeshttps://doi.org/10.1007/s12672-023-00701-7openalex-snapshot

Possible therapeutic targets for NLRP3 inflammasome-induced breast cancer

inferred← citeshttps://doi.org/10.1007/s13258-021-01152-6openalex-snapshot

Inhibition of FOSL2 aggravates the apoptosis of ovarian cancer cells by promoting the formation of inflammasomes

inferred← citeshttps://doi.org/10.1007/s40265-023-01838-zopenalex-snapshot

A Review of RRx-001: A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation

inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.11167-5openalex-snapshot

Role of Inflammation and Inflammasomes in Bone Pathophysiology

inferred← citeshttps://doi.org/10.1016/b978-0-12-812102-3.00004-xopenalex-snapshot

Innate and Adaptive Systems of Immunity

inferred← citeshttps://doi.org/10.1016/b978-0-12-820476-4.00043-6openalex-snapshot

Inflammation

inferred← citeshttps://doi.org/10.1016/b978-0-323-54755-0.00001-2openalex-snapshot

Basic Principles of Pathology

inferred← citeshttps://doi.org/10.1016/b978-0-323-63600-1.00003-xopenalex-snapshot

10.1016/b978-0-323-63600-1.00003-x

inferred← citeshttps://doi.org/10.1016/b978-0-323-85654-6.00052-6openalex-snapshot

Inflammation as a mediator of stress-related psychiatric disorders

inferred← citeshttps://doi.org/10.1016/b978-0-323-87822-7.00001-8openalex-snapshot

Basic Principles of Pathology

inferred← citeshttps://doi.org/10.1016/b978-0-323-91802-2.00036-0openalex-snapshot

Regulation of neutrophil NETosis by inflammasome

inferred← citeshttps://doi.org/10.1016/b978-0-323-99570-2.00003-5openalex-snapshot

Role of pattern recognition receptors in cardiac remodeling

inferred← citeshttps://doi.org/10.1016/bs.ant.2026.03.011openalex-snapshot

Synaptic health in brain disorders: Impact of nanoplastic exposure

inferred← citeshttps://doi.org/10.1016/bs.ant.2026.03.012openalex-snapshot

Developmental exposure to microplastics: A hidden threat to early brain maturation

inferred← citeshttps://doi.org/10.1016/bs.apcsb.2019.08.007openalex-snapshot

Microglial NLRP3 inflammasome activation in multiple sclerosis

inferred← citeshttps://doi.org/10.1016/bs.mie.2019.07.008openalex-snapshot

Protein interactions of the inflammasome adapter ASC by solution NMR

inferred← citeshttps://doi.org/10.1016/j.abb.2019.05.023openalex-snapshot

Structure, interactions and self-assembly of ASC-dependent inflammasomes

inferred← citeshttps://doi.org/10.1016/j.abb.2026.110885openalex-snapshot

The neuroprotective effect of eugenol in aluminum chloride-induced Alzheimer's rats: Insights into the role of TLR4/MyD88/NF-kB and NLRP3 inflammasome/gasdermin D signaling pathways

inferred← citeshttps://doi.org/10.1016/j.acthis.2024.152211openalex-snapshot

RETRACTED: miR-103-3p attenuates liver injury with severe acute pancreatitis by inhibiting pyroptosis through miR-103-3p/NLRP1 axis

inferred← citeshttps://doi.org/10.1016/j.arr.2019.100966openalex-snapshot

Is Alzheimer’s disease an inflammasomopathy?

inferred← citeshttps://doi.org/10.1016/j.arr.2020.101192openalex-snapshot

The involvement of NLRP3 inflammasome in the treatment of Alzheimer’s disease

inferred← citeshttps://doi.org/10.1016/j.autrev.2018.01.020openalex-snapshot

NLRP3: A promising therapeutic target for autoimmune diseases

inferred← citeshttps://doi.org/10.1016/j.bbcan.2020.188357openalex-snapshot

Caspase-8: The double-edged sword

inferred← citeshttps://doi.org/10.1016/j.bbi.2018.09.001openalex-snapshot

Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke

inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114861openalex-snapshot

Luxeptinib disables NLRP3 inflammasome-mediated IL-1β release and pathways required for secretion of inflammatory cytokines IL-6 and TNFα

inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115569openalex-snapshot

Targeting the NLRP3 inflammasome in diabetic retinopathy: From pathogenesis to therapeutic strategies

inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115861openalex-snapshot

NLRP3 inflammasome in hepatic diseases: A pharmacological target

inferred← citeshttps://doi.org/10.1016/j.bcp.2026.118057openalex-snapshot

ISG15/ISGylation in central nervous system diseases: molecular mechanisms and therapeutic targeting

inferred← citeshttps://doi.org/10.1016/j.biocel.2021.106013openalex-snapshot

Mitochondrial dysfunction as a driver of NLRP3 inflammasome activation and its modulation through mitophagy for potential therapeutics

inferred← citeshttps://doi.org/10.1016/j.biocel.2025.106880openalex-snapshot

Paxillin mediates lung epithelial injury by activating NLRP3 inflammasomes in an acute respiratory distress syndrome mouse model

inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.109537openalex-snapshot

Inhibition of the NLRP3 pathway as a strategy for SLE therapy

inferred← citeshttps://doi.org/10.1016/j.biopha.2021.111428openalex-snapshot

The involvement of NLRP3 inflammasome in the treatment of neurodegenerative diseases

inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115393openalex-snapshot

Role of the NLRP3 inflammasome in gynecological disease

inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115692openalex-snapshot

The role of hepatocyte mitochondrial DNA in liver injury

inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118110openalex-snapshot

Mitigation of nicotine-induced podocyte injury through inhibition of thioredoxin interacting protein

inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118286openalex-snapshot

Pyroptosis in acute respiratory distress syndrome and pulmonary fibrosis

inferred← citeshttps://doi.org/10.1016/j.brainresbull.2019.10.010openalex-snapshot

Involvement of NLRC4 inflammasome through caspase-1 and IL-1β augments neuroinflammation and contributes to memory impairment in an experimental model of Alzheimer's like disease

inferred← citeshttps://doi.org/10.1016/j.brainresbull.2024.110964openalex-snapshot

Argon neuroprotection in ischemic stroke and its underlying mechanism

inferred← citeshttps://doi.org/10.1016/j.cell.2024.09.032openalex-snapshot

IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer

inferred← citeshttps://doi.org/10.1016/j.cellsig.2020.109552openalex-snapshot

Synergistic activation of p53 by actinomycin D and nutlin-3a is associated with the upregulation of crucial regulators and effectors of innate immunity

inferred← citeshttps://doi.org/10.1016/j.celrep.2021.108887openalex-snapshot

Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

inferred← citeshttps://doi.org/10.1016/j.celrep.2023.112728openalex-snapshot

Mitochondria-derived cell-to-cell communication

inferred← citeshttps://doi.org/10.1016/j.celrep.2025.116232openalex-snapshot

Emerging roles for innate and adaptive immunity in tauopathies

inferred← citeshttps://doi.org/10.1016/j.clim.2022.109013openalex-snapshot

The critical role of short-chain fatty acids in health and disease: A subtle focus on cardiovascular disease-NLRP3 inflammasome-angiogenesis axis

inferred← citeshttps://doi.org/10.1016/j.crimmu.2021.10.005openalex-snapshot

Extracellular vesicles derived from head and neck squamous cells carcinoma inhibit NLRP3 inflammasomes

inferred← citeshttps://doi.org/10.1016/j.csbj.2021.07.038openalex-snapshot

From pyroptosis, apoptosis and necroptosis to PANoptosis: A mechanistic compendium of programmed cell death pathways

inferred← citeshttps://doi.org/10.1016/j.ctarc.2022.100545openalex-snapshot

Studying ferroptosis and pyroptosis as new cell death mechanisms induced by ionizing radiation in Ehrlich solid tumor-bearing mice

inferred← citeshttps://doi.org/10.1016/j.cyto.2022.155808openalex-snapshot

Multifaceted roles of IL-38 in inflammation and cancer

inferred← citeshttps://doi.org/10.1016/j.cyto.2023.156347openalex-snapshot

Role of inflammasomes and cytokines in immune dysfunction of liver cirrhosis

inferred← citeshttps://doi.org/10.1016/j.dci.2019.103523openalex-snapshot

Characterization of immune response against Mycobacterium marinum infection in the main hematopoietic organ of adult zebrafish (Danio rerio)

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.118921openalex-snapshot

Blue light induces corneal epithelial damage by activating the NLRP3 inflammasome pathway

inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113417openalex-snapshot

Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities

inferred← citeshttps://doi.org/10.1016/j.ejphar.2022.175468openalex-snapshot

20(S)-Protopanaxatriol ameliorates MAFLD by inhibiting NLRP3 inflammasome

inferred← citeshttps://doi.org/10.1016/j.ejphar.2026.179140openalex-snapshot

Trichostatin A improves impaired autophagic flux associated with ERK/FoxO3a signaling to alleviate acute pancreatitis

inferred← citeshttps://doi.org/10.1016/j.eng.2025.07.039openalex-snapshot

Xuanfei Baidu Formula Ameliorates Influenza A Virus-Induced Lung Inflammation by Repressing the NLRP3 Inflammasome in Macrophages

inferred← citeshttps://doi.org/10.1016/j.envint.2024.108631openalex-snapshot

Methylmercury induces inflammatory response and autophagy in microglia through the activation of NLRP3 inflammasome

inferred← citeshttps://doi.org/10.1016/j.exer.2021.108687openalex-snapshot

Antimycin A-induced mitochondrial dysfunction regulates inflammasome signaling in human retinal pigment epithelial cells

inferred← citeshttps://doi.org/10.1016/j.exer.2024.109952openalex-snapshot

Protective effects of curcumin on corneal endothelial cell PANoptosis and monocyte adhesion induced by tumor necrosis factor-alpha and interferon-gamma in rats

inferred← citeshttps://doi.org/10.1016/j.expneurol.2019.113080openalex-snapshot

Neural-respiratory inflammasome axis in traumatic brain injury

inferred← citeshttps://doi.org/10.1016/j.expneurol.2021.113943openalex-snapshot

Astrocytes in the Traumatic Brain Injury: the Good and the Bad

inferred← citeshttps://doi.org/10.1016/j.foodres.2026.118559openalex-snapshot

Water-soluble tomato concentrate combats vascular aging through the regulation of endothelial cell senescence via DNA-sensing AIM2 inflammasome

inferred← citeshttps://doi.org/10.1016/j.fsi.2025.110676openalex-snapshot

Zebrafish Kat7b can up-regulate Nek7 to promote the NLRP3 inflammasome signaling pathway inhibited by β-sitosterol

inferred← citeshttps://doi.org/10.1016/j.gendis.2023.01.009openalex-snapshot

Fantastic voyage: The journey of NLRP3 inflammasome activation

inferred← citeshttps://doi.org/10.1016/j.gene.2025.149546openalex-snapshot

Targeting programmed cell death pathways in gastric cancer: a focus on pyroptosis, apoptosis, necroptosis and PANoptosis

inferred← citeshttps://doi.org/10.1016/j.humimm.2025.111610openalex-snapshot

NLRP3 genetic variants and their impact on psoriasis susceptibility, severity, and risk of psoriatic arthritis

inferred← citeshttps://doi.org/10.1016/j.intimp.2020.106520openalex-snapshot

Physiological concentrations of bilirubin control inflammatory response by inhibiting NF-κB and inflammasome activation

inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110103openalex-snapshot

Hesperetin ameliorates spinal cord injury by inhibiting NLRP3 inflammasome activation and pyroptosis through enhancing Nrf2 signaling

inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110362openalex-snapshot

LMCD1 is involved in tubulointerstitial inflammation in the early phase of renal fibrosis by promoting NFATc1-mediated NLRP3 activation

inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110423openalex-snapshot

Eleutheroside E from pre-treatment of Acanthopanax senticosus (Rupr.etMaxim.) Harms ameliorates high-altitude-induced heart injury by regulating NLRP3 inflammasome-mediated pyroptosis via NLRP3/caspase-1 pathway

inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113006openalex-snapshot

Inflammation unleashed: The role of pyroptosis in chronic liver diseases

inferred← citeshttps://doi.org/10.1016/j.isci.2021.102103openalex-snapshot

Regulatory T cells induced by B cells suppress NLRP3 inflammasome activation and alleviate monosodium urate-induced gouty inflammation

inferred← citeshttps://doi.org/10.1016/j.jare.2024.06.010openalex-snapshot

Pyroptosis: A spoiler of peaceful coexistence between cells in degenerative bone and joint diseases

inferred← citeshttps://doi.org/10.1016/j.jbc.2022.101566openalex-snapshot

Inflammasome regulation by adaptor isoforms, ASC and ASCb, via differential self-assembly

inferred← citeshttps://doi.org/10.1016/j.jchemneu.2024.102393openalex-snapshot

Oxyberberine protects middle cerebral artery occlusion triggered cerebral injury through TLR4/NLRP3 pathway in rats

inferred← citeshttps://doi.org/10.1016/j.jcjd.2020.11.003openalex-snapshot

Effect of Empagliflozin and Liraglutide on the Nucleotide-Binding and Oligomerization Domain-Like Receptor Family Pyrin Domain-Containing 3 Inflammasome in a Rodent Model of Type 2 Diabetes Mellitus

inferred← citeshttps://doi.org/10.1016/j.jddst.2025.106803openalex-snapshot

Cationic lipid based nanoparticles-formulated artesunate as a neurotherapeutic agent in Alzheimer's disease: Targeting inflammasome activation and pyroptosis pathway

inferred← citeshttps://doi.org/10.1016/j.jep.2021.114715openalex-snapshot

Panaxadiol inhibits IL-1β secretion by suppressing zinc finger protein 91-regulated activation of non-canonical caspase-8 inflammasome and MAPKs in macrophages

inferred← citeshttps://doi.org/10.1016/j.jep.2025.120104openalex-snapshot

Cornus officinalis loganin attenuates acute lung injury in mice via regulating the PI3K/AKT/NLRP3 axis

inferred← citeshttps://doi.org/10.1016/j.jmb.2021.167301openalex-snapshot

Pyroptosis-Induced Inflammation and Tissue Damage

inferred← citeshttps://doi.org/10.1016/j.jphs.2025.09.003openalex-snapshot

Endothelial NLRP3-mediated pyroptosis induces blood-brain barrier and neuronal damage in Huntington's disease models

inferred← citeshttps://doi.org/10.1016/j.jri.2023.104173openalex-snapshot

NLRP3 inflammasome pathway, the hidden balance in pregnancy: A comprehensive review

inferred← citeshttps://doi.org/10.1016/j.jtos.2024.09.007openalex-snapshot

Recent advances in NLRP3 inflammasome in corneal diseases: Preclinical insights and therapeutic implications

inferred← citeshttps://doi.org/10.1016/j.lfs.2023.122076openalex-snapshot

Reactive oxygen species trigger inflammasome activation after intracellular microbial interaction

inferred← citeshttps://doi.org/10.1016/j.mam.2020.100887openalex-snapshot

NLRP12 in innate immunity and inflammation

inferred← citeshttps://doi.org/10.1016/j.metabol.2019.153989openalex-snapshot

HFD refeeding in mice after fasting impairs learning by activating caspase-1 in the brain

inferred← citeshttps://doi.org/10.1016/j.molimm.2018.12.024openalex-snapshot

Inflammasome activation and Th17 responses

inferred← citeshttps://doi.org/10.1016/j.molimm.2023.06.007openalex-snapshot

Potential roles of inflammasomes in the pathophysiology of Psoriasis: A comprehensive review

inferred← citeshttps://doi.org/10.1016/j.mtadv.2022.100252openalex-snapshot

Harnessing chitosan and poly-(γ-glutamic acid)-based biomaterials towards cancer immunotherapy

inferred← citeshttps://doi.org/10.1016/j.nano.2022.102548openalex-snapshot

Macrophage-targeted shikonin-loaded nanogels for modulation of inflammasome activation

inferred← citeshttps://doi.org/10.1016/j.nbd.2019.104578openalex-snapshot

Finding intestinal fortitude: Integrating the microbiome into a holistic view of depression mechanisms, treatment, and resilience

inferred← citeshttps://doi.org/10.1016/j.neubiorev.2022.104969openalex-snapshot

Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview

inferred← citeshttps://doi.org/10.1016/j.neuint.2024.105747openalex-snapshot

The Janus face of HIF-1α in ischemic stroke and the possible associated pathways

inferred← citeshttps://doi.org/10.1016/j.neulet.2021.135954openalex-snapshot

BRCC3 promotes activation of the NLRP6 inflammasome following cerebral ischemia/reperfusion (I/R) injury in rats

inferred← citeshttps://doi.org/10.1016/j.neuro.2023.06.006openalex-snapshot

Fisetin attenuates arsenic and fluoride subacute co-exposure induced neurotoxicity via regulating TNF-α mediated activation of NLRP3 inflammasome

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2020.09.036openalex-snapshot

Hypoxia Inducible Factor-1α (HIF-1α) Mediates NLRP3 Inflammasome-Dependent-Pyroptotic and Apoptotic Cell Death Following Ischemic Stroke

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2024.03.029openalex-snapshot

Mechanism of NLRP3 Inflammasome in Epilepsy and Related Therapeutic Agents

inferred← citeshttps://doi.org/10.1016/j.npep.2025.102521openalex-snapshot

Netrin-3 enhances recovery and reduces inflammation following spinal cord injury via suppressing NLRP1 inflammasome activation

inferred← citeshttps://doi.org/10.1016/j.parint.2020.102119openalex-snapshot

Angiostrongylus cantonensis activates inflammasomes in meningoencephalitic BALB/c mice

inferred← citeshttps://doi.org/10.1016/j.phrs.2021.105447openalex-snapshot

Pyroptosis is a critical immune-inflammatory response involved in atherosclerosis

inferred← citeshttps://doi.org/10.1016/j.phrs.2022.106635openalex-snapshot

Cell death regulation: A new way for natural products to treat osteoporosis

inferred← citeshttps://doi.org/10.1016/j.phrs.2024.107383openalex-snapshot

Cell life-or-death events in osteoporosis: All roads lead to mitochondrial dynamics

inferred← citeshttps://doi.org/10.1016/j.phymed.2023.155193openalex-snapshot

Lupeol alleviates autoimmune myocarditis by suppressing macrophage pyroptosis and polarization via PPARα/LACC1/NF-κB signaling pathway

inferred← citeshttps://doi.org/10.1016/j.phymed.2024.155516openalex-snapshot

Luteolin rescues postmenopausal osteoporosis elicited by OVX through alleviating osteoblast pyroptosis via activating PI3K-AKT signaling

inferred← citeshttps://doi.org/10.1016/j.phymed.2025.156394openalex-snapshot

Natural products target pyroptosis for ameliorating neuroinflammation: A novel antidepressant strategy

inferred← citeshttps://doi.org/10.1016/j.phymed.2026.158707openalex-snapshot

Elucidating the therapeutic potential of natural products in alleviating diabetic cardiomyopathy: contemporary progress and forthcoming opportunities

inferred← citeshttps://doi.org/10.1016/j.preghy.2024.101142openalex-snapshot

Association of NLRP3 and IL-4 VNTR polymorphisms and genetic susceptibility to preeclampsia: A case-control study

inferred← citeshttps://doi.org/10.1016/j.retram.2020.07.003openalex-snapshot

Mechanistic insights into the role of pyroptosis in rheumatoid arthritis

inferred← citeshttps://doi.org/10.1016/j.reuma.2020.06.004openalex-snapshot

Respuesta inflamatoria en relación con COVID-19 y otros fenotipos protrombóticos

inferred← citeshttps://doi.org/10.1016/j.reumae.2020.06.007openalex-snapshot

Inflammatory response in relation to COVID-19 and other prothrombotic phenotypes

inferred← citeshttps://doi.org/10.1016/j.smim.2018.10.006openalex-snapshot

Interleukin-1α as an intracellular alarmin in cancer biology

inferred← citeshttps://doi.org/10.1016/j.taap.2023.116672openalex-snapshot

Quercetin inhibits the NOX2/ROS-mediated NF-κB/TXNIP signaling pathway to ameliorate pyroptosis of cardiomyocytes to relieve sepsis-induced cardiomyopathy

inferred← citeshttps://doi.org/10.1016/j.tox.2020.152668openalex-snapshot

Ozone exposure promotes pyroptosis in rat lungs via the TLR2/4-NF-κB-NLRP3 signaling pathway

inferred← citeshttps://doi.org/10.1016/j.trsl.2022.08.011openalex-snapshot

The NLRP3 inflammasome fires up heme-induced inflammation in hemolytic conditions

inferred← citeshttps://doi.org/10.1016/j.trsl.2022.08.014openalex-snapshot

Inflammasome activation in traumatic brain injury and Alzheimer's disease

inferred← citeshttps://doi.org/10.1016/j.trsl.2023.02.001openalex-snapshot

Genetic predisposition to Alzheimer's disease alters inflammasome activity after traumatic brain injury

inferred← citeshttps://doi.org/10.1016/j.virol.2022.01.003openalex-snapshot

SARS-CoV-2 viroporin encoded by ORF3a triggers the NLRP3 inflammatory pathway

inferred← citeshttps://doi.org/10.1016/j.yexcr.2023.113860openalex-snapshot

Cell death classification: A new insight based on molecular mechanisms

inferred← citeshttps://doi.org/10.1016/j.ymthe.2024.04.007openalex-snapshot

Interaction of SMAC with a survivin-derived peptide alters essential cancer hallmarks: Tumor growth, inflammation, and immunosuppression

inferred← citeshttps://doi.org/10.1021/acs.chemrestox.9b00467openalex-snapshot

Safe-by-Design of Glucan Nanoparticles: Size Matters When Assessing the Immunotoxicity

inferred← citeshttps://doi.org/10.1021/acs.jafc.0c06534openalex-snapshot

Lycopene Ameliorates Di(2-ethylhexyl) Phthalate-Induced Pyroptosis in Spleen via Suppression of Classic Caspase-1/NLRP3 Pathway

inferred← citeshttps://doi.org/10.1038/s41392-021-00687-0openalex-snapshot

Pattern recognition receptors in health and diseases

inferred← citeshttps://doi.org/10.1038/s41401-020-00603-2openalex-snapshot

NOD-like receptors in autoimmune diseases

inferred← citeshttps://doi.org/10.1038/s41467-019-09753-2openalex-snapshot

Caspase-1 initiates apoptosis in the absence of gasdermin D

inferred← citeshttps://doi.org/10.1038/s41467-022-28967-5openalex-snapshot

CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT

inferred← citeshttps://doi.org/10.1038/s41467-026-69398-wopenalex-snapshot

Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancer

inferred← citeshttps://doi.org/10.1038/s41584-018-0078-5openalex-snapshot

Calcium crystal deposition diseases — beyond gout

inferred← citeshttps://doi.org/10.1038/s41586-020-2025-2openalex-snapshot

Pathway paradigms revealed from the genetics of inflammatory bowel disease

inferred← citeshttps://doi.org/10.1038/s41590-021-00886-5openalex-snapshot

NLRP3 inflammasome in cancer and metabolic diseases

inferred← citeshttps://doi.org/10.1038/s41598-018-35792-8openalex-snapshot

CASP4 gene silencing in epithelial cancer cells leads to impairment of cell migration, cell-matrix adhesion and tissue invasion

inferred← citeshttps://doi.org/10.1038/s41598-020-70102-1openalex-snapshot

Treatment of mice with S4B6 IL-2 complex prevents lethal toxoplasmosis via IL-12- and IL-18-dependent interferon-gamma production by non-CD4 immune cells

inferred← citeshttps://doi.org/10.1038/s41598-021-93831-3openalex-snapshot

The immunoregulatory function of peripheral blood CD71+ erythroid cells in systemic-onset juvenile idiopathic arthritis

inferred← citeshttps://doi.org/10.1038/s41598-021-94850-wopenalex-snapshot

A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

inferred← citeshttps://doi.org/10.1038/s41598-024-75805-3openalex-snapshot

Inhibition of NLRP3 inflammasome contributes to paclitaxel efficacy in triple negative breast cancer treatment

inferred← citeshttps://doi.org/10.1053/j.gastro.2018.11.081openalex-snapshot

Genetics, Cell Biology, and Pathophysiology of Pancreatitis

inferred← citeshttps://doi.org/10.1056/evidoa2200145openalex-snapshot

Oral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19: Interim Analysis

inferred← citeshttps://doi.org/10.1057/s41599-026-07758-zopenalex-snapshot

Psychological significance of cross boarder FDI in perceived subjective well-being of indigenous communities: insights from resettlement practices

inferred← citeshttps://doi.org/10.1080/08830185.2022.2052064openalex-snapshot

Pyroptosis in neurodegenerative diseases: What lies beneath the tip of the iceberg?

inferred← citeshttps://doi.org/10.1080/0886022x.2025.2538798openalex-snapshot

Mechanisms of NLRP3 inflammasome in chronic kidney disease and the effects of traditional Chinese medicines

inferred← citeshttps://doi.org/10.1080/1061186x.2025.2474644openalex-snapshot

Development of a bio-inspired phagocytic stable nanoghost with anti-inflammatory properties for management of inflammation in ulcerative colitis

inferred← citeshttps://doi.org/10.1080/10641963.2020.1867159openalex-snapshot

Expression of urotensin II is positively correlated with pyroptosis-related molecules in patients with severe preeclampsia

inferred← citeshttps://doi.org/10.1080/14728222.2019.1599359openalex-snapshot

Opportunities for future therapeutic interventions for hyperoxaluria: targeting oxidative stress

inferred← citeshttps://doi.org/10.1080/14728222.2020.1738391openalex-snapshot

Alzheimer’s disease: microglia targets and their modulation to promote amyloid phagocytosis and mitigate neuroinflammation

inferred← citeshttps://doi.org/10.1080/14728222.2024.2366872openalex-snapshot

Targeting inflammasome complexes as a novel therapeutic strategy for mood disorders

inferred← citeshttps://doi.org/10.1080/15548627.2023.2249392openalex-snapshot

Pristimerin suppresses AIM2 inflammasome by modulating AIM2-PYCARD/ASC stability via selective autophagy to alleviate tendinopathy

inferred← citeshttps://doi.org/10.1080/1744666x.2021.1937129openalex-snapshot

Regulation of crystal induced inflammation: current understandings and clinical implications

inferred← citeshttps://doi.org/10.1080/26895293.2025.2543709openalex-snapshot

Research progress in mechanisms of neurotoxicity induced by micro(nano)plastic exposure

inferred← citeshttps://doi.org/10.1089/vim.2020.0227openalex-snapshot

Activation of Interleukin-1 β Release and Pyroptosis by Transmissible Gastroenteritis Virus Is Dependent on the NOD-Like Receptor Protein 3 Inflammasome in Porcine Intestinal Epithelial Cell Line

inferred← citeshttps://doi.org/10.1089/vim.2022.0010openalex-snapshot

Pathway of Cell Death and Its Role in Virus Infection

inferred← citeshttps://doi.org/10.1093/abbs/gmab137openalex-snapshot

NLRP3 inflammasome signal pathway involves in Vibrio harveyi-induced inflammatory response in murine peritoneal macrophages in vitro

inferred← citeshttps://doi.org/10.1093/jleuko/qiae206openalex-snapshot

Neonatal neutrophils exhibit reduced NLRP3 inflammasome activation

inferred← citeshttps://doi.org/10.1093/jmcb/mjac077openalex-snapshot

Argon mitigates post-stroke neuroinflammation by regulating M1/M2 polarization and inhibiting NF-κB/NLRP3 inflammasome signaling

inferred← citeshttps://doi.org/10.1093/jnen/nlae066openalex-snapshot

Increased inflammasome protein expression identified in microglia from postmortem brains with schizophrenia

inferred← citeshttps://doi.org/10.1093/jnen/nlag014openalex-snapshot

Cross-talk between pyroptosis and miRNAs in Alzheimer disease neuropathology, therapeutic targeting of NLRP inflammasomes, and recent advances in nanoparticle-targeted therapy

inferred← citeshttps://doi.org/10.1093/nutrit/nuac039openalex-snapshot

Insights into diet-associated oxidative pathomechanisms in inflammatory bowel disease and protective effects of functional amino acids

inferred← citeshttps://doi.org/10.1093/rheumatology/key438openalex-snapshot

Emerging roles for chemokines and cytokines as orchestrators of immunopathology in Sjögren’s syndrome

inferred← citeshttps://doi.org/10.1093/rheumatology/kez296openalex-snapshot

Calcium crystals and auto-inflammation

showing the first 200 of 454 · page through all 454

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.