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Possible Association of Acute Lateral-Wall Myocardial Infarction and Bitter Orange Supplement

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.289.19.2560openalex-snapshot
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure The JNC 7 Report
inferredcites →https://doi.org/10.1002/clc.4960200505openalex-snapshot
Coronary risk factors, endothelial function, and atherosclerosis: A review
inferredcites →https://doi.org/10.1016/0024-3205(95)02195-oopenalex-snapshot
Fructus aurantii reduced portal pressure in portal hypertensive rats
inferredcites →https://doi.org/10.1016/s0095-4543(03)00006-xopenalex-snapshot
The prevalence of obesity
inferredcites →https://doi.org/10.1016/s0367-326x(99)00093-3openalex-snapshot
Antiobesity and cardiovascular toxic effects of Citrus aurantium extracts in the rat: a preliminary report
inferredcites →https://doi.org/10.1016/s0731-7085(02)00153-xopenalex-snapshot
Determination of adrenergic agonists from extracts and herbal products of Citrus aurantium L. var. amara by LC
inferredcites →https://doi.org/10.1038/clpt.1981.154openalex-snapshot
A method for estimating the probability of adverse drug reactions
inferredcites →https://doi.org/10.1056/nejm199907223410402openalex-snapshot
Sex, Clinical Presentation, and Outcome in Patients with Acute Coronary Syndromes
inferredcites →https://doi.org/10.1097/00002826-200305000-00005openalex-snapshot
Medications and Substances as a Cause of Headache: A Systematic Review of the Literature
inferredcites →https://doi.org/10.1097/00005768-200210000-00022openalex-snapshot
Symposium: conference on the science and policy of performance-enhancing products
inferredcites →https://doi.org/10.1126/science.301.5640.1669copenalex-snapshot
Ephedra-Free Is Not Danger-Free
inferredcites →https://doi.org/10.1136/bmj.291.6500.940openalex-snapshot
Unreviewed Reports
inferredcites →https://doi.org/10.1177/00912700122012652openalex-snapshot
Seville (sour) Orange Juice: Synephrine Content and Cardiovascular Effects in Normotensive Adults
inferredcites →https://doi.org/10.5860/choice.46-0032openalex-snapshot
Natural Medicines Comprehensive Database
inferredcites →https://doi.org/10.7326/0003-4819-111-5-447_3openalex-snapshot
Pharmacotherapy: A Pathophysiologic Approach

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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The Safety of Citrus aurantium (Bitter Orange) and its Primary Protoalkaloid p‐Synephrine
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Glutamine Parenteral Nutrition in Pneumonia
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Over-the-Counter Nutritional Supplements: Implications for Critically Ill Patients
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Weight Loss Ingredients
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Citrus aurantium
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Pharmacological Treatment of the Overweight Patient
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Sympathomimetic Agents
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Sympathomimetic Agents
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Structural isomerization of synephrine influences its uptake and ensuing glutathione depletion in rat-isolated cardiomyocytes
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Aurantii Fructus: a systematic review of ethnopharmacology, phytochemistry and pharmacology
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Cardiovascular Toxicity of Citrus aurantium in Exercised Rats
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Review of Case Reports on Adverse Events Related to Pre-workout Supplements Containing Synephrine
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Role of Selected Medicinal Plants in Sports Nutrition and Energy Homeostasis
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Herbal Medicines – Acanthaceae – Zygophyllaceae
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Rutaceae
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Hemodynamic effects of ephedra-free weight-loss supplements in humans
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Advising Patients Who Use Dietary Supplements
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Multi-ingredient, Caffeine-containing Dietary Supplements: History, Safety, and Efficacy
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Herbalists’ perception of risks involving commonly sold medicinal plants in Italy
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Concentrations of p-synephrine in fruits and leaves of Citrus species (Rutaceae) and the acute toxicity testing of Citrus aurantium extract and p-synephrine
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Synephrine: From trace concentrations to massive consumption in weight-loss
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Synephrine: From trace concentrations to massive consumption in weight-loss
inferred← citeshttps://doi.org/10.1016/j.fct.2013.07.041openalex-snapshot
Investigating herb–drug interactions: The effect of Citrus aurantium fruit extract on the pharmacokinetics of amiodarone in rats
inferred← citeshttps://doi.org/10.1016/j.foodchem.2020.127306openalex-snapshot
Sweet and bitter oranges: An updated comparative review of their bioactives, nutrition, food quality, therapeutic merits and biowaste valorization practices
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Arrhythmogenicity of weight-loss supplements marketed on the Internet
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Integrating Complementary Medicine Into Cardiovascular Medicine
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Unexplained Supraventricular Tachycardia and Myocardial Injury After Bitter Orange Supplement Use in a Young Woman
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Availability of Weight-Loss Supplements: Results of an Audit of Retail Outlets in a Southeastern City
inferred← citeshttps://doi.org/10.1016/j.jccase.2016.12.008openalex-snapshot
Ascending aortic dissection in a young patient using a synephrine-containing workout supplement
inferred← citeshttps://doi.org/10.1016/j.jep.2025.120917openalex-snapshot
A review of ethnoveterinary botanical medicines used in Uganda: Their phytochemistry, bioactivity and toxicity
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Assessment of the adverse event reports associated with Citrus aurantium (bitter orange) from April 2004 to October 2009
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Canadian Consensus on Female Nutrition: Adolescence, Reproduction, Menopause, and Beyond
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Consensus canadien sur la nutrition féminine : adolescence, reproduction, ménopause et au-delà
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Development and validation of a GC/IT-MS method for simultaneous quantitation of para and meta-synephrine in biological samples
inferred← citeshttps://doi.org/10.1016/j.microc.2023.109809openalex-snapshot
Determination of synephrine in herbal plants using an isotopically labeled internal standard HPLC–MS/MS method
inferred← citeshttps://doi.org/10.1016/j.taap.2012.04.006openalex-snapshot
Physiological effects following administration of Citrus aurantium for 28 days in rats
inferred← citeshttps://doi.org/10.1016/j.tox.2019.04.010openalex-snapshot
Analysis of the cytotoxic, genotoxic, mutagenic, and pro-oxidant effect of synephrine, a component of thermogenic supplements, in human hepatic cells in vitro
inferred← citeshttps://doi.org/10.1016/j.yrtph.2009.03.001openalex-snapshot
Subchronic toxicity of Citrus aurantium L. (Rutaceae) extract and p-synephrine in mice
inferred← citeshttps://doi.org/10.1016/s0001-4079(19)33710-0openalex-snapshot
Dopage et compléments alimentaires
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48 Treatments used in complementary and alternative medicine
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Mass Spectrometric Determination of the Predominant Adrenergic Protoalkaloids in Bitter Orange (Citrus aurantium)
inferred← citeshttps://doi.org/10.1038/clpt.2012.241openalex-snapshot
Multiple Dosing of Ephedra-Free Dietary Supplements: Hemodynamic, Electrocardiographic, and Bacterial Contamination Effects
inferred← citeshttps://doi.org/10.1039/c1np00035gopenalex-snapshot
Natural products in anti-obesity therapy
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Herbs–Are they Safe Enough? An Overview
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Heart Toxicity Related to Herbs and Dietary Supplements: Online Table of Case Reports. Part 4 of 5.
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Review of Published Bitter Orange Extract and p-Synephrine Adverse Event Clinical Study Case Reports
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Ephedra
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Analysis of Ephedra-Free Labeled Dietary Supplements Sold in the San Francisco Bay Area in 2003
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Evaluation of the Stimulant Content of Dietary Supplements Marketed as “Ephedra-Free”
inferred← citeshttps://doi.org/10.1093/chromsci/46.1.61openalex-snapshot
Determination of Caffeine and Sympathomimetic Alkaloids in Weight Loss Supplements by High-Performance Liquid Chromatography
inferred← citeshttps://doi.org/10.1093/jaoac/90.1.68openalex-snapshot
Determination of Synephrine in Bitter Orange Raw Materials, Extracts, and Dietary Supplements by Liquid Chromatography with Ultraviolet Detection: Single-Laboratory Validation
inferred← citeshttps://doi.org/10.1097/asa.0b013e31825f1b6aopenalex-snapshot
Anesthesia and Herbal Supplements
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Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update
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Dietary Supplements for Improving Body Composition and Reducing Body Weight: Where Is the Evidence?
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Pharmacological Treatment of the Overweight Patient
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Avaliação da mutagenicidade, genotoxicidade e alterações no perfil de expressão gênica induzida pela sinefrina em células humanas >i /i<
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Herbal Product Contamination and Toxicity
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Toxicological Effects of a Mixture Used in Weight Loss Products: p -Synephrine Associated With Ephedrine, Salicin, and Caffeine
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A Review of the Safety and Efficacy of Citrus aurantium in Weight Management
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References
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Encyclopedia of Dietary Supplements
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Bitter Orange
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Safety issues associated with commercially available energy drinks
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Assessment of herbal weight loss supplement counseling provided to patients by pharmacists and nonpharmacists in community settings
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Potential for toxicity with use of bitter orange extract and guarana for weight loss
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Perceived Efficacy, Indications, and Information Sources for Medically Indigent Patients and Their Healthcare Providers Regarding Dietary Supplements
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Blood Pressure and Heart Rate Effects Following a Single Dose of Bitter Orange
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Coronary vasospasm and raspberry ketones weight-loss supplement – is there a link?
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Absence of QTc‐Interval–Prolonging or Hemodynamic Effects of a Single Dose of Bitter‐Orange Extract in Healthy Subjects
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Patient's knowledge and awareness about the effect of the over-the-counter (OTC) drugs and dietary supplements on laboratory test results: a survey in 18 European countries
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Risk assessment of synephrine
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An Evidence-Based Systematic Review of Bitter Orange (Citrus aurantium) by the Natural Standard Research Collaboration
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Suppressive Effect of Citrus aurantium against Body Fat Accumulation and Its Safety
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Effect of Citrus Aurantium Combined with Caffeine and/or Tea Catechins on Body Fat Accumulation and Its Safety in Rats
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Synephrine in dietary supplements and specialized foodstuffs: biological activity, safety and methods of analysis
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Pharmacoepidemiological Data on Drug–Herb Interactions: Serotonin Syndrome, Arrhythmias and the Emerging Role of Artificial Intelligence
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Mise en contexte
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Exercise-Induced Syncope Associated With QT Prolongation and Ephedra-Free Xenadrine
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Ischemic Stroke Associated With Use of an Ephedra-Free Dietary Supplement Containing Synephrine
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Ischemic Colitis Associated With Use of a Bitter Orange-Containing Dietary Weight-Loss Supplement
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Reporting Associations Between Dietary Supplements and Adverse Events–Reply–I
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Variant Angina Associated With Bitter Orange in a Dietary Supplement
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An overview of Citrus aurantium used in treatment of various diseases
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Ventricular Fibrillation Associated With Use of Synephrine Containing Dietary Supplement
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