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PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1006/bbrc.1999.1145openalex-snapshot
Role of the β3-Adrenergic Receptor and/or a Putative β4-Adrenergic Receptor on the Expression of Uncoupling Proteins and Peroxisome Proliferator-Activated Receptor-γ Coactivator-1
inferredcites →https://doi.org/10.1006/bbrc.2000.3134openalex-snapshot
cDNA Cloning and mRNA Analysis of PGC-1 in Epitrochlearis Muscle in Swimming-Exercised Rats
inferredcites →https://doi.org/10.1007/978-1-4615-5653-4_7openalex-snapshot
Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo
inferredcites →https://doi.org/10.1007/s00125-002-0783-zopenalex-snapshot
No association between the G482S polymorphism of the proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene and Type II diabetes in French Caucasians.
inferredcites →https://doi.org/10.1007/s00125-002-0803-zopenalex-snapshot
A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes
inferredcites →https://doi.org/10.1007/s001250100032openalex-snapshot
Mutation analysis of peroxisome proliferator-activated receptor-γ coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus
inferredcites →https://doi.org/10.1016/j.cell.2004.09.013openalex-snapshot
Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice
inferredcites →https://doi.org/10.1016/s0002-9440(10)63565-1openalex-snapshot
Non-Obese Diabetic Mice Rapidly Develop Dramatic Sympathetic Neuritic Dystrophy
inferredcites →https://doi.org/10.1016/s0006-291x(02)00881-1openalex-snapshot
Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle
inferredcites →https://doi.org/10.1016/s0021-9258(19)47245-1openalex-snapshot
The Tissue-specific Expression and Developmental Regulation of Two Nuclear Genes Encoding Rat Mitochondrial Proteins
inferredcites →https://doi.org/10.1016/s0092-8674(00)80611-xopenalex-snapshot
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
inferredcites →https://doi.org/10.1016/s0092-8674(00)81410-5openalex-snapshot
A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
inferredcites →https://doi.org/10.1016/s0896-6273(02)00744-4openalex-snapshot
Ataxia and Paroxysmal Dyskinesia in Mice Lacking Axonally Transported FGF14
inferredcites →https://doi.org/10.1016/s1043-2760(01)00457-xopenalex-snapshot
PGC-1, a versatile coactivator
inferredcites →https://doi.org/10.1016/s1096-7192(03)00017-9openalex-snapshot
Characterization of fatty acid oxidation in human muscle mitochondria and myoblasts
inferredcites →https://doi.org/10.1023/a:1006834912257openalex-snapshot
Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vitro
inferredcites →https://doi.org/10.1038/35093050openalex-snapshot
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
inferredcites →https://doi.org/10.1038/35093131openalex-snapshot
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
inferredcites →https://doi.org/10.1038/35098123openalex-snapshot
Erratum: correction: CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
inferredcites →https://doi.org/10.1038/nature00904openalex-snapshot
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
inferredcites →https://doi.org/10.1038/nature01667openalex-snapshot
Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
inferredcites →https://doi.org/10.1038/ng1180openalex-snapshot
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
inferredcites →https://doi.org/10.1038/nm1044openalex-snapshot
PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3
inferredcites →https://doi.org/10.1038/nm898openalex-snapshot
Dexamethasone induction of hypertension and diabetes is PPAR-α dependent in LDL receptor–null mice
inferredcites →https://doi.org/10.1056/nejmoa031314openalex-snapshot
Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
inferredcites →https://doi.org/10.1073/pnas.0401401101openalex-snapshot
Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
inferredcites →https://doi.org/10.1073/pnas.1032913100openalex-snapshot
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
inferredcites →https://doi.org/10.1073/pnas.88.18.8277openalex-snapshot
RETRACTED: Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy.
inferredcites →https://doi.org/10.1074/jbc.c100631200openalex-snapshot
Peroxisome Proliferator-activated Receptor γ Coactivator 1β (PGC-1β), A Novel PGC-1-related Transcription Coactivator Associated with Host Cell Factor
inferredcites →https://doi.org/10.1074/jbc.m004913200openalex-snapshot
A Targeted Apolipoprotein B-38.9-producing Mutation Causes Fatty Livers in Mice Due to the Reduced Ability of Apolipoprotein B-38.9 to Transport Triglycerides
inferredcites →https://doi.org/10.1074/jbc.m201134200openalex-snapshot
The PGC-1-related Protein PERC Is a Selective Coactivator of Estrogen Receptor α
inferredcites →https://doi.org/10.1096/fj.02-0367comopenalex-snapshot
Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC‐1
inferredcites →https://doi.org/10.1097/01.wcb.0000122743.72175.52openalex-snapshot
Quantitative RT-PCR Analysis of Uncoupling Protein Isoforms in Mouse Brain Cortex: Methodological Optimization and Comparison of Expression with Brown Adipose Tissue and Skeletal Muscle
inferredcites →https://doi.org/10.1101/gad.1138104openalex-snapshot
Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) regulates triglyceride metabolism by activation of the nuclear receptor FXR
inferredcites →https://doi.org/10.1101/gad.1177604openalex-snapshot
Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
inferredcites →https://doi.org/10.1113/jphysiol.2002.034850openalex-snapshot
Exercise induces transient transcriptional activation of the PGC‐1α gene in human skeletal muscle
inferredcites →https://doi.org/10.1126/science.1082889openalex-snapshot
Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance
inferredcites →https://doi.org/10.1128/mcb.20.5.1868-1876.2000openalex-snapshot
The Coactivator PGC-1 Cooperates with Peroxisome Proliferator-Activated Receptor α in Transcriptional Control of Nuclear Genes Encoding Mitochondrial Fatty Acid Oxidation Enzymes
inferredcites →https://doi.org/10.1128/mcb.21.11.3738-3749.2001openalex-snapshot
PGC-1-Related Coactivator, a Novel, Serum-Inducible Coactivator of Nuclear Respiratory Factor 1-Dependent Transcription in Mammalian Cells
inferredcites →https://doi.org/10.1128/mcb.23.22.7947-7956.2003openalex-snapshot
Reduced Fat Mass in Mice Lacking Orphan Nuclear Receptor Estrogen-Related Receptor α
inferredcites →https://doi.org/10.1128/mcb.24.20.9079-9091.2004openalex-snapshot
Estrogen-Related Receptor α Directs Peroxisome Proliferator-Activated Receptor α Signaling in the Transcriptional Control of Energy Metabolism in Cardiac and Skeletal Muscle
inferredcites →https://doi.org/10.1152/ajpcell.00409.2002openalex-snapshot
PPARγ coactivator-1α expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations
inferredcites →https://doi.org/10.1152/ajpcell.1996.270.5.c1413openalex-snapshot
Activation of a novel metabolic gene regulatory pathway by chronic stimulation of skeletal muscle
inferredcites →https://doi.org/10.1152/ajpcell.1999.277.6.c1210openalex-snapshot
Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter
inferredcites →https://doi.org/10.1152/ajpendo.00051.2003openalex-snapshot
Effects of acute bouts of running and swimming exercise on PGC-1α protein expression in rat epitrochlearis and soleus muscle
inferredcites →https://doi.org/10.1152/ajpheart.1998.274.5.h1828openalex-snapshot
End-systolic stress-velocity and pressure-dimension relationships by transthoracic echocardiography in mice
inferredcites →https://doi.org/10.1152/ajpregu.1999.277.4.r1210openalex-snapshot
Glucose and fatty acid metabolism in the isolated working mouse heart
inferredcites →https://doi.org/10.1161/01.atv.0000019404.65403.71openalex-snapshot
Respiratory Uncoupling Lowers Blood Pressure Through a Leptin-Dependent Mechanism in Genetically Obese Mice
inferredcites →https://doi.org/10.1161/01.hyp.0000050962.48249.b7openalex-snapshot
Peroxisome Proliferator–Activated Receptor-γ Coactivator-1 Gene Locus
inferredcites →https://doi.org/10.1161/01.res.0000117088.36577.ebopenalex-snapshot
Cardiac-Specific Induction of the Transcriptional Coactivator Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Promotes Mitochondrial Biogenesis and Reversible Cardiomyopathy in a Developmental Stage-Dependent Manner
inferredcites →https://doi.org/10.1172/jci10268openalex-snapshot
Peroxisome proliferator–activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis
inferredcites →https://doi.org/10.1172/jci11497openalex-snapshot
PPARα deficiency reduces insulin resistance and atherosclerosis in apoE-null mice
inferredcites →https://doi.org/10.1172/jci6713openalex-snapshot
RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload
inferredcites →https://doi.org/10.1210/er.2002-0012openalex-snapshot
Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator
inferredcites →https://doi.org/10.1523/jneurosci.20-13-04809.2000openalex-snapshot
Altered Stress-Induced Anxiety in Adenylyl Cyclase Type VIII-Deficient Mice
inferredcites →https://doi.org/10.2337/diabetes.51.4.1281openalex-snapshot
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 Gene Locus
inferredcites →https://doi.org/10.2337/diabetes.53.5.1385openalex-snapshot
Complex Haplotypes of the PGC-1α Gene Are Associated With Carbohydrate Metabolism and Type 2 Diabetes
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Visualizing the Role of ER Stress in Diabetic Cardiomyopathy: A Bibliometric Analysis
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PI3K/PTEN signaling in liver diseases
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A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat
inferred← citeshttps://doi.org/10.1002/ana.24294openalex-snapshot
Mutual exacerbation of peroxisome proliferator‐activated receptor γ coactivator 1α deregulation and α‐synuclein oligomerization
inferred← citeshttps://doi.org/10.1002/cne.21211openalex-snapshot
Localization of the transcriptional coactivator PGC‐1α to GABAergic neurons during maturation of the rat brain
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Mechanisms of Exercise‐Induced Mitochondrial Biogenesis in Skeletal Muscle: Implications for Health and Disease
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Physiological Systems in Promoting Frailty
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Insulin Regulation of Hepatic Lipid Homeostasis
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Molecular pathways regulating the formation of brown‐like adipocytes in white adipose tissue
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Peri‐implantation lethality in mice lacking the PGC‐1‐related coactivator protein
inferred← citeshttps://doi.org/10.1002/em.20575openalex-snapshot
Mitochondrial dysfunction in neurodegenerative diseases and cancer
inferred← citeshttps://doi.org/10.1002/hep.23719openalex-snapshot
Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis
inferred← citeshttps://doi.org/10.1002/hep.27437openalex-snapshot
Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism
inferred← citeshttps://doi.org/10.1002/iub.1097openalex-snapshot
Peroxisome proliferator‐activated receptor‐γ cofactors in neurodegeneration
inferred← citeshttps://doi.org/10.1002/iub.164openalex-snapshot
Age‐associated mitochondrial dysfunction in skeletal muscle: Contributing factors and suggestions for long‐term interventions
inferred← citeshttps://doi.org/10.1002/iub.32openalex-snapshot
The role of PAS kinase in regulating energy metabolism
inferred← citeshttps://doi.org/10.1002/iub.342openalex-snapshot
cAMP/Ca2+ response element‐binding protein plays a central role in the biogenesis of respiratory chain proteins in mammalian cells
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2011.tb00370.xopenalex-snapshot
Mechanisms of Exercise‐Induced Mitochondrial Biogenesis in Skeletal Muscle: Implications for Health and Disease
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2022.tb00224.xopenalex-snapshot
Physiological Systems in Promoting Frailty
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2023.tb00269.xopenalex-snapshot
Insulin Regulation of Hepatic Lipid Homeostasis
inferred← citeshttps://doi.org/10.1002/jcp.22812openalex-snapshot
Enhanced lipid—but not carbohydrate—supported mitochondrial respiration in skeletal muscle of PGC‐1α overexpressing mice
inferred← citeshttps://doi.org/10.1002/jcp.25735openalex-snapshot
Fibroblast Growth Factor 21 (FGF21) Promotes Formation of Aerobic Myofibers via the FGF21‐SIRT1‐AMPK‐PGC1α Pathway
inferred← citeshttps://doi.org/10.1002/jcp.25840openalex-snapshot
Mimicking exercise in three‐dimensional bioengineered skeletal muscle to investigate cellular and molecular mechanisms of physiological adaptation
inferred← citeshttps://doi.org/10.1002/jcsm.12846openalex-snapshot
AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology
inferred← citeshttps://doi.org/10.1002/jcsm.70090openalex-snapshot
Skeletal Muscle PGC‐1α Remodels Mitochondrial Phospholipidome but Does Not Alter Energy Efficiency for ATP Synthesis
inferred← citeshttps://doi.org/10.1002/jsfa.9352openalex-snapshot
Dietary salmon milt extracts attenuate hepatosteatosis and liver dysfunction in diet‐induced fatty liver model
inferred← citeshttps://doi.org/10.1002/mco2.70285openalex-snapshot
Sulfide Quinone Oxidoreductase Alleviates Acute Ulcerative Colitis by Regulating Mitochondrial Dysfunction
inferred← citeshttps://doi.org/10.1002/mus.22217openalex-snapshot
PGC‐1α protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model
inferred← citeshttps://doi.org/10.1002/path.5631openalex-snapshot
TWEAK–Fn14 as a common pathway in the heart and the kidneys in cardiorenal syndrome
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The wasting‐associated metabolite succinate disrupts myogenesis and impairs skeletal muscle regeneration
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Cardiac function and disease: emerging role of small ubiquitin‐related modifier
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Signaling Pathways Controlling Muscle Fiber Size and Type In Response To Nerve Activity
inferred← citeshttps://doi.org/10.1007/5584_2022_742openalex-snapshot
HSF1 and Its Role in Huntington’s Disease Pathology
inferred← citeshttps://doi.org/10.1007/978-0-387-30411-3_29openalex-snapshot
7.3 Transcriptional Integration of Mitochondrial Biogenesis
inferred← citeshttps://doi.org/10.1007/978-1-0716-2213-1_1openalex-snapshot
Cell-Based Assays to Identify ERR and ERR/PGC Modulators
inferred← citeshttps://doi.org/10.1007/978-1-4419-7130-2_9openalex-snapshot
Cardiac Dysfunction and Metabolism: Unravelling the Molecular Cross-Talk
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Bigenomic Regulation of Cytochrome c Oxidase in Neurons and the Tight Coupling Between Neuronal Activity and Energy Metabolism
inferred← citeshttps://doi.org/10.1007/978-1-4614-4599-9_18openalex-snapshot
Mitochondria Play an Essential Role in Heart Failure
inferred← citeshttps://doi.org/10.1007/978-1-4939-1227-8_6openalex-snapshot
Transcriptional Control of Mitochondrial Biogenesis and Maturation
inferred← citeshttps://doi.org/10.1007/978-1-60327-043-4_4openalex-snapshot
Fat Metabolism in Insulin Resistance and Type 2 Diabetes
inferred← citeshttps://doi.org/10.1007/978-1-60761-147-9_5openalex-snapshot
The Multidimensional Role of Mitochondria in Heart Failure
inferred← citeshttps://doi.org/10.1007/978-1-61779-891-7_4openalex-snapshot
PPAR/PGC-1 Regulation of Metabolism in Cardiac Disease
inferred← citeshttps://doi.org/10.1007/978-3-030-04816-7_3openalex-snapshot
Exercise and the Mitochondria
inferred← citeshttps://doi.org/10.1007/978-3-031-15613-7_17openalex-snapshot
Targeting the Mitochondrion in Diabetic Neuropathy
inferred← citeshttps://doi.org/10.1007/978-3-031-63657-8_2openalex-snapshot
Misalignment of Circadian Rhythms in Diet-Induced Obesity
inferred← citeshttps://doi.org/10.1007/978-3-031-88361-3_2openalex-snapshot
Mitochondrial Biogenesis in Skeletal Muscle
inferred← citeshttps://doi.org/10.1007/978-3-031-88361-3_21openalex-snapshot
Training-Induced Metabolic Adaptations in Skeletal Muscle
inferred← citeshttps://doi.org/10.1007/978-3-319-01008-3_6openalex-snapshot
The Skeletal Muscle in Metabolic Syndrome
inferred← citeshttps://doi.org/10.1007/978-3-319-19821-7_2openalex-snapshot
Brown Adipose Tissue and Obesity
inferred← citeshttps://doi.org/10.1007/978-3-319-48382-5_2openalex-snapshot
Circadian Rhythms in Diet-Induced Obesity
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Mitochondria and Cardiac Hypertrophy
inferred← citeshttps://doi.org/10.1007/978-3-319-55330-6_28openalex-snapshot
Mitochondrial Dysfunction in the Diabetic Kidney
inferred← citeshttps://doi.org/10.1007/978-3-319-57193-5_4openalex-snapshot
Huntington’s Disease: Pathogenic Mechanisms and Therapeutic Targets
inferred← citeshttps://doi.org/10.1007/978-3-642-13517-0_8openalex-snapshot
Transcriptional Regulation of Brown and White Adipogenesis
inferred← citeshttps://doi.org/10.1007/978-88-470-0376-7_3openalex-snapshot
Exercise-Induced Mitochondrial Biogenesis in Skeletal Muscle
inferred← citeshttps://doi.org/10.1007/978-88-470-0376-7_9openalex-snapshot
Mitochondria in Cell Life and Death
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The Role and Regulation of PGC-1α and PGC-1β in Skeletal Muscle Adaptation
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High-Throughput Screening and Hazard Testing Prioritization
inferred← citeshttps://doi.org/10.1007/s00018-006-6600-yopenalex-snapshot
Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise
inferred← citeshttps://doi.org/10.1007/s00018-012-1025-2openalex-snapshot
Energy dysfunction in Huntington’s disease: insights from PGC-1α, AMPK, and CKB
inferred← citeshttps://doi.org/10.1007/s00018-014-1574-7openalex-snapshot
Circadian clocks and energy metabolism
inferred← citeshttps://doi.org/10.1007/s00109-023-02326-3openalex-snapshot
Mitochondrial transplantation as a possible therapeutic option for sarcopenia
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PGC-1α: a potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes
inferred← citeshttps://doi.org/10.1007/s00125-006-0467-1openalex-snapshot
Amelioration of glucose tolerance by hepatic inhibition of nuclear factor κB in db/db mice
inferred← citeshttps://doi.org/10.1007/s00125-008-1050-8openalex-snapshot
Sequence variation between the mouse and human glucose-6-phosphatase catalytic subunit gene promoters results in differential activation by peroxisome proliferator activated receptor gamma coactivator-1α
inferred← citeshttps://doi.org/10.1007/s00125-013-2971-4openalex-snapshot
Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function
inferred← citeshttps://doi.org/10.1007/s00204-014-1336-1openalex-snapshot
Hepatotoxic effects of (tri)azole fungicides in a broad dose range
inferred← citeshttps://doi.org/10.1007/s00204-023-03488-2openalex-snapshot
Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes
inferred← citeshttps://doi.org/10.1007/s00210-024-03316-zopenalex-snapshot
Empagliflozin demonstrates cytotoxicity and synergy with tamoxifen in ER-positive breast cancer cells: anti-proliferative and anti-survival effects
inferred← citeshttps://doi.org/10.1007/s00246-011-9889-8openalex-snapshot
Peroxisome Proliferator Activated Receptor-Alpha (PPARα) and PPAR Gamma Coactivator-1alpha (PGC-1α) Regulation of Cardiac Metabolism in Diabetes
inferred← citeshttps://doi.org/10.1007/s00281-013-0406-4openalex-snapshot
Functional crosstalk of PGC-1 coactivators and inflammation in skeletal muscle pathophysiology
inferred← citeshttps://doi.org/10.1007/s00335-019-09802-7openalex-snapshot
Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis
inferred← citeshttps://doi.org/10.1007/s00395-011-0213-9openalex-snapshot
Mitochondrial biogenesis and PGC-1α deacetylation by chronic treadmill exercise: differential response in cardiac and skeletal muscle
inferred← citeshttps://doi.org/10.1007/s00424-010-0834-0openalex-snapshot
PGC-1α-mediated adaptations in skeletal muscle
inferred← citeshttps://doi.org/10.1007/s00424-017-2076-xopenalex-snapshot
Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts
inferred← citeshttps://doi.org/10.1007/s00438-015-1026-6openalex-snapshot
Transcriptome analysis reveals the potential contribution of long noncoding RNAs to brown adipocyte differentiation
inferred← citeshttps://doi.org/10.1007/s00439-012-1205-zopenalex-snapshot
Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset
inferred← citeshttps://doi.org/10.1007/s00705-013-1892-3openalex-snapshot
Hepatitis C virus nonstructural protein 5A favors upregulation of gluconeogenic and lipogenic gene expression leading towards insulin resistance: a metabolic syndrome
inferred← citeshttps://doi.org/10.1007/s00726-015-2126-7openalex-snapshot
β-Hydroxy-β-methylbutyrate, mitochondrial biogenesis, and skeletal muscle health
inferred← citeshttps://doi.org/10.1007/s10059-013-2336-3openalex-snapshot
A Nutrigenomic Framework to Identify Time-Resolving Responses of Hepatic Genes in Diet-Induced Obese Mice
inferred← citeshttps://doi.org/10.1007/s10103-026-04976-4openalex-snapshot
10.6 μm laser moxibustion can improve oxidative stress and abnormal energy metabolism in liver of hypothyroidism rats through Nrf2/HO-1 and Nrf2/PGC-1α/TFAM pathways
inferred← citeshttps://doi.org/10.1007/s10522-008-9177-zopenalex-snapshot
Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated mice
inferred← citeshttps://doi.org/10.1007/s10565-022-09716-2openalex-snapshot
Mitochondrial quality control in cardiac ischemia/reperfusion injury: new insights into mechanisms and implications
inferred← citeshttps://doi.org/10.1007/s10616-018-0242-4openalex-snapshot
Cyanidin-3-glucoside enhances mitochondrial function and biogenesis in a human hepatocyte cell line
inferred← citeshttps://doi.org/10.1007/s10620-007-0193-7openalex-snapshot
The Transition from Fatty Liver to NASH Associates with SAMe Depletion in db/db Mice Fed a Methionine Choline-Deficient Diet
inferred← citeshttps://doi.org/10.1007/s10753-014-9850-0openalex-snapshot
PGC-1α Expression Is Increased in Leukocytes in Experimental Acute Pancreatitis
inferred← citeshttps://doi.org/10.1007/s10863-010-9290-yopenalex-snapshot
Mitochondrial matters of the brain: the role in Huntington’s disease
inferred← citeshttps://doi.org/10.1007/s10863-014-9576-6openalex-snapshot
Impaired mitochondrial homeostasis and neurodegeneration: towards new therapeutic targets?
inferred← citeshttps://doi.org/10.1007/s10863-017-9736-6openalex-snapshot
Adrenaline induces mitochondrial biogenesis in rat liver
inferred← citeshttps://doi.org/10.1007/s11010-010-0520-8openalex-snapshot
Activation of PPARδ promotes mitochondrial energy metabolism and decreases basal insulin secretion in palmitate-treated β-cells
inferred← citeshttps://doi.org/10.1007/s11010-011-0789-2openalex-snapshot
Overexpression of PGC-1β improves insulin sensitivity and mitochondrial function in 3T3-L1 adipocytes
inferred← citeshttps://doi.org/10.1007/s11010-017-3010-4openalex-snapshot
IGF-II-mediated downregulation of peroxisome proliferator-activated receptor-γ coactivator-1α in myoblast cells involves PI3K/Akt/FoxO1 signaling pathway
inferred← citeshttps://doi.org/10.1007/s11033-011-1172-9openalex-snapshot
Polymorphisms of the 5′ regulatory region of the porcine PPARGC1A gene and the effects on muscle fiber characteristics and meat quality
inferred← citeshttps://doi.org/10.1007/s11064-019-02809-1openalex-snapshot
PGC-1α, Sirtuins and PARPs in Huntington’s Disease and Other Neurodegenerative Conditions: NAD+ to Rule Them All
inferred← citeshttps://doi.org/10.1007/s11154-013-9260-xopenalex-snapshot
Role of oxytocin signaling in the regulation of body weight
inferred← citeshttps://doi.org/10.1007/s11154-013-9273-5openalex-snapshot
Genetic models of PGC-1 and glucose metabolism and homeostasis
inferred← citeshttps://doi.org/10.1007/s11154-016-9358-zopenalex-snapshot
The effects of indoor and outdoor temperature on metabolic rate and adipose tissue – the Mississippi perspective on the obesity epidemic
inferred← citeshttps://doi.org/10.1007/s11427-015-4833-4openalex-snapshot
Transcriptional regulatory circuits controlling muscle fiber type switching
inferred← citeshttps://doi.org/10.1007/s11596-012-1041-3openalex-snapshot
Role of neuropeptide Y and peroxisome proliferator-activated receptor γ coactivator-1α in stress cardiomyopathy
inferred← citeshttps://doi.org/10.1007/s11626-021-00595-1openalex-snapshot
Therapeutic potential of ginsenoside Rg3 and Rf for Huntington’s disease
inferred← citeshttps://doi.org/10.1007/s11892-015-0671-9openalex-snapshot
Mitochondrial Dysfunction in Diabetic Neuropathy: a Series of Unfortunate Metabolic Events
inferred← citeshttps://doi.org/10.1007/s11894-009-0083-6openalex-snapshot
Nontriglyceride Hepatic Lipotoxicity: The New Paradigm for the Pathogenesis of NASH
inferred← citeshttps://doi.org/10.1007/s11897-012-0102-zopenalex-snapshot
AMP-activated Protein Kinase in the Control of Cardiac Metabolism and Remodeling
inferred← citeshttps://doi.org/10.1007/s12017-018-8486-xopenalex-snapshot
Thermodynamics in Neurodegenerative Diseases: Interplay Between Canonical WNT/Beta-Catenin Pathway–PPAR Gamma, Energy Metabolism and Circadian Rhythms
inferred← citeshttps://doi.org/10.1007/s12035-009-8095-7openalex-snapshot
Abnormal Mitochondrial Dynamics—A Novel Therapeutic Target for Alzheimer's Disease?
inferred← citeshttps://doi.org/10.1007/s12035-015-9090-9openalex-snapshot
The Neuro-Immune Pathophysiology of Central and Peripheral Fatigue in Systemic Immune-Inflammatory and Neuro-Immune Diseases
inferred← citeshttps://doi.org/10.1007/s12035-020-01900-xopenalex-snapshot
Muscarinic Toxin 7 Signals Via Ca2+/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration
inferred← citeshttps://doi.org/10.1007/s12035-025-05611-zopenalex-snapshot
Deciphering the PGC-1α-TFAM Axis in Parkinson’s Disease (PD) — A Mechanism Approach Targeting Therapeutics for PD
inferred← citeshttps://doi.org/10.1007/s12041-008-0067-6openalex-snapshot
Energy-responsive timekeeping
inferred← citeshttps://doi.org/10.1007/s13105-011-0083-5openalex-snapshot
Expression of nuclear-encoded genes involved in mitochondrial biogenesis and dynamics in experimentally denervated muscle
inferred← citeshttps://doi.org/10.1007/s40519-018-0622-yopenalex-snapshot
PGC-1α activation: a therapeutic target for type 2 diabetes?
inferred← citeshttps://doi.org/10.1007/s43440-024-00619-zopenalex-snapshot
Mitochondrial targeted antioxidants as potential therapy for huntington’s disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-375003-7.00004-2openalex-snapshot
The Genetics of Brown Adipose Tissue
inferred← citeshttps://doi.org/10.1016/b978-0-12-381328-2.00015-8openalex-snapshot
Pathogenic Mechanisms in Huntington's Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-381510-1.00016-8openalex-snapshot
Transcriptional Control of Striated Muscle Mitochondrial Biogenesis and Function
inferred← citeshttps://doi.org/10.1016/b978-0-12-381510-1.00059-4openalex-snapshot
Skeletal Muscle Metabolism
inferred← citeshttps://doi.org/10.1016/b978-0-12-381510-1.00064-8openalex-snapshot
Skeletal Muscle Adaptation to Exercise
inferred← citeshttps://doi.org/10.1016/b978-0-12-404599-6.00013-5openalex-snapshot
Gene Profiling, Energy Metabolism, and Remodeling of the Failing Heart
inferred← citeshttps://doi.org/10.1016/b978-0-12-404599-6.00016-0openalex-snapshot
Post-Genomic Analysis of Fatty Acid and Glucose Metabolism in Cardiovascular Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.11474-6openalex-snapshot
Mitochondria and Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-802394-5.00003-0openalex-snapshot
Metabolically Relevant Cell Biology – Role of Intracellular Organelles for Cardiac Metabolism
inferred← citeshttps://doi.org/10.1016/b978-0-12-813553-2.00007-5openalex-snapshot
Obesity, mitochondrial dysfunction, and obstructive lung disease
inferred← citeshttps://doi.org/10.1016/b978-0-323-90456-8.00012-0openalex-snapshot
Triplicated HSA21 genes and mtDNA on mitochondrial dysfunction
inferred← citeshttps://doi.org/10.1016/b978-0-443-15260-3.00018-1openalex-snapshot
Molecular regulation of mitochondrial turnover by exercise: tissue adaptation through mitochondrial biogenesis and mitophagy
inferred← citeshttps://doi.org/10.1016/b978-0-444-63233-3.00011-7openalex-snapshot
The CAG–polyglutamine repeat diseases: a clinical, molecular, genetic, and pathophysiologic nosology
inferred← citeshttps://doi.org/10.1016/b978-0-444-64074-1.00047-1openalex-snapshot
Thermoregulatory disorders in Huntington disease
inferred← citeshttps://doi.org/10.1016/b978-1-4160-6641-5.00024-6openalex-snapshot
Etiology, Pathology, and Pathogenesis
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2024.01.005openalex-snapshot
The role of metabolism in cardiac development
inferred← citeshttps://doi.org/10.1016/bs.irn.2019.04.002openalex-snapshot
Role of mitochondria in diabetic peripheral neuropathy: Influencing the NAD+-dependent SIRT1–PGC-1α–TFAM pathway
inferred← citeshttps://doi.org/10.1016/j.abb.2022.109150openalex-snapshot
Plantar stimulation prevents the decrease in fatigue resistance in rat soleus muscle under one week of hindlimb suspension
inferred← citeshttps://doi.org/10.1016/j.abb.2022.109445openalex-snapshot
Selenium and selenoproteins in thermogenic adipocytes
inferred← citeshttps://doi.org/10.1016/j.addr.2010.09.016openalex-snapshot
Nuclear receptor coregulators as a new paradigm for therapeutic targeting
inferred← citeshttps://doi.org/10.1016/j.apsb.2020.10.007openalex-snapshot
Energy metabolism disorders and potential therapeutic drugs in heart failure
inferred← citeshttps://doi.org/10.1016/j.arr.2009.03.003openalex-snapshot
The coordination of nuclear and mitochondrial communication during aging and calorie restriction
inferred← citeshttps://doi.org/10.1016/j.arr.2018.03.004openalex-snapshot
PGC-1α sparks the fire of neuroprotection against neurodegenerative disorders
inferred← citeshttps://doi.org/10.1016/j.arr.2018.10.004openalex-snapshot
Genetic modifiers of age-at-onset in polyglutamine diseases
inferred← citeshttps://doi.org/10.1016/j.bbabio.2007.11.003openalex-snapshot
Mitochondrial biogenesis in fast skeletal muscle of CK deficient mice
inferred← citeshttps://doi.org/10.1016/j.bbabio.2010.02.017openalex-snapshot
Alterations in the mitochondrial regulatory pathways constituted by the nuclear co-factors PGC-1α or PGC-1β and mitofusin 2 in skeletal muscle in type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.bbadis.2009.08.001openalex-snapshot
Downstream mechanisms triggered by mitochondrial dysfunction in the basal ganglia: From experimental models to neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.bbadis.2011.11.014openalex-snapshot
Antioxidants in Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.bbadis.2016.01.019openalex-snapshot
Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system
inferred← citeshttps://doi.org/10.1016/j.bbadis.2021.166208openalex-snapshot
Mitochondrial function, dynamics and quality control in the pathophysiology of HFpEF
inferred← citeshttps://doi.org/10.1016/j.bbadis.2023.166877openalex-snapshot
Downregulation of PGC-1α during cisplatin-induced muscle atrophy in murine skeletal muscle
inferred← citeshttps://doi.org/10.1016/j.bbagen.2009.04.005openalex-snapshot
PGC-1α in aging and anti-aging interventions
inferred← citeshttps://doi.org/10.1016/j.bbagen.2016.10.022openalex-snapshot
Globular CTRP3 promotes mitochondrial biogenesis in cardiomyocytes through AMPK/PGC-1α pathway
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2011.10.011openalex-snapshot
Nucleus-encoded regulators of mitochondrial function: Integration of respiratory chain expression, nutrient sensing and metabolic stress
inferred← citeshttps://doi.org/10.1016/j.bbalip.2009.11.008openalex-snapshot
ADD1/SREBP1c activates the PGC1-α promoter in brown adipocytes
inferred← citeshttps://doi.org/10.1016/j.bbalip.2024.159590openalex-snapshot
Hippo pathway activation causes multiple lipid derangements in a murine model of cardiomyopathy
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2010.09.019openalex-snapshot
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2012.08.015openalex-snapshot
Perturbations in the gene regulatory pathways controlling mitochondrial energy production in the failing heart
inferred← citeshttps://doi.org/10.1016/j.bbapap.2009.11.023openalex-snapshot
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
inferred← citeshttps://doi.org/10.1016/j.bbr.2016.07.021openalex-snapshot
Lack of age-related clinical progression in PGC-1α-deficient mice – implications for mitochondrial encephalopathies
inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.03.126openalex-snapshot
Estrogen-related receptor α is essential for the expression of antioxidant protection genes and mitochondrial function
inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.07.079openalex-snapshot
Potential role of lipin-1 in exercise-induced mitochondrial biogenesis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.12.109openalex-snapshot
Identification of novel targets for PGC-1α and histone deacetylase inhibitors in neuroblastoma cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2010.05.018openalex-snapshot
PGC-1α accelerates cytosolic Ca2+ clearance without disturbing Ca2+ homeostasis in cardiac myocytes
inferred← citeshttps://doi.org/10.1016/j.bbrc.2014.01.033openalex-snapshot
Development of a stable cell line with an intact PGC-1α/ERRα axis for screening environmental chemicals
inferred← citeshttps://doi.org/10.1016/j.bbrc.2014.01.188openalex-snapshot
Study of cholesterol metabolism in Huntington′s disease
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.09.063openalex-snapshot
Carbon monoxide stimulates astrocytic mitochondrial biogenesis via L-type Ca 2+ channel-mediated PGC-1α/ERRα activation
inferred← citeshttps://doi.org/10.1016/j.bcp.2015.06.032openalex-snapshot
Pharmacological induction of mitochondrial biogenesis as a therapeutic strategy for the treatment of type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115717openalex-snapshot
Peroxisom proliferator-activated receptor-γ coactivator-1α in neurodegenerative disorders: A promising therapeutic target
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116137openalex-snapshot
Adipose tissue in cortisol excess: What Cushing’s syndrome can teach us?
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116185openalex-snapshot
Transcriptional control of cardiac energy metabolism in health and disease: Lessons from animal models
inferred← citeshttps://doi.org/10.1016/j.biocel.2009.02.004openalex-snapshot
Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.biocel.2011.10.001openalex-snapshot
Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis
inferred← citeshttps://doi.org/10.1016/j.biocel.2022.106361openalex-snapshot
Roles of lipid metabolism and its regulatory mechanism in idiopathic pulmonary fibrosis: A review
inferred← citeshttps://doi.org/10.1016/j.biochi.2012.09.025openalex-snapshot
24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115271openalex-snapshot
Energy metabolism: A critical target of cardiovascular injury
inferred← citeshttps://doi.org/10.1016/j.biopsych.2011.07.012openalex-snapshot
Prioritization and Association Analysis of Murine-Derived Candidate Genes in Anxiety-Spectrum Disorders
inferred← citeshttps://doi.org/10.1016/j.biopsych.2017.11.018openalex-snapshot
Mitochondrial Etiology of Neuropsychiatric Disorders
inferred← citeshttps://doi.org/10.1016/j.brainres.2007.07.063openalex-snapshot
Quantitative immuno-electron microscopic analysis of depolarization-induced expression of PGC-1α in cultured rat visual cortical neurons
inferred← citeshttps://doi.org/10.1016/j.brainres.2010.03.082openalex-snapshot
Differential gene expression between neuropeptide Y expressing neurons of the dorsomedial nucleus of the Hypothalamus and the Arcuate Nucleus: Microarray Analysis Study
inferred← citeshttps://doi.org/10.1016/j.cardiores.2006.08.023openalex-snapshot
The PPAR regulatory system in cardiac physiology and disease
inferred← citeshttps://doi.org/10.1016/j.cbpa.2019.04.011openalex-snapshot
Metabolic regulation by the PGC-1α and PGC-1β coactivators in larval zebrafish (Danio rerio)
inferred← citeshttps://doi.org/10.1016/j.cca.2008.08.011openalex-snapshot
PPAR-α L162V and PGC-1 G482S gene polymorphisms, but not PPAR-γ P12A, are associated with alcohol consumption in a Spanish Mediterranean population
inferred← citeshttps://doi.org/10.1016/j.cell.2006.09.015openalex-snapshot
Transcriptional Repression of PGC-1α by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration
inferred← citeshttps://doi.org/10.1016/j.cell.2006.09.024openalex-snapshot
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
inferred← citeshttps://doi.org/10.1016/j.cell.2006.10.023openalex-snapshot
PGC-1α, a New Therapeutic Target in Huntington's Disease?
inferred← citeshttps://doi.org/10.1016/j.cell.2006.11.013openalex-snapshot
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
inferred← citeshttps://doi.org/10.1016/j.cell.2025.06.029openalex-snapshot
A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons
inferred← citeshttps://doi.org/10.1016/j.cellsig.2018.02.009openalex-snapshot
Physiological functions of FBW7 in cancer and metabolism
inferred← citeshttps://doi.org/10.1016/j.cellsig.2024.111478openalex-snapshot
Sirt1-mediated deacetylation of PGC-1α alleviated hepatic steatosis in type 2 diabetes mellitus via improving mitochondrial fatty acid oxidation
inferred← citeshttps://doi.org/10.1016/j.celrep.2013.04.023openalex-snapshot
Disconnecting Mitochondrial Content from Respiratory Chain Capacity in PGC-1-Deficient Skeletal Muscle
inferred← citeshttps://doi.org/10.1016/j.celrep.2013.05.030openalex-snapshot
RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression
inferred← citeshttps://doi.org/10.1016/j.celrep.2013.05.032openalex-snapshot
Nontelomeric Role for Rap1 in Regulating Metabolism and Protecting against Obesity
inferred← citeshttps://doi.org/10.1016/j.celrep.2014.04.046openalex-snapshot
Inhibition of Endothelial p53 Improves Metabolic Abnormalities Related to Dietary Obesity
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.06.006openalex-snapshot
Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.01.087openalex-snapshot
Loss of Hepatic Oscillatory Fed microRNAs Abrogates Refed Transition and Causes Liver Dysfunctions
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.108952openalex-snapshot
Mitochondrial biogenesis in developing astrocytes regulates astrocyte maturation and synapse formation
inferred← citeshttps://doi.org/10.1016/j.cmet.2005.05.004openalex-snapshot
Metabolic control through the PGC-1 family of transcription coactivators
inferred← citeshttps://doi.org/10.1016/j.cmet.2005.08.010openalex-snapshot
The orphan nuclear receptor SHP regulates PGC-1α expression and energy production in brown adipocytes
inferred← citeshttps://doi.org/10.1016/j.cmet.2006.04.002openalex-snapshot
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
inferred← citeshttps://doi.org/10.1016/j.cmet.2006.08.005openalex-snapshot
Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway
inferred← citeshttps://doi.org/10.1016/j.cmet.2006.10.003openalex-snapshot
PGC1α expression is controlled in skeletal muscles by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.cmet.2006.10.004openalex-snapshot
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration
inferred← citeshttps://doi.org/10.1016/j.cmet.2007.01.003openalex-snapshot
Ménage-à-Trois 1 Is Critical for the Transcriptional Function of PPARγ Coactivator 1
inferred← citeshttps://doi.org/10.1016/j.cmet.2007.06.005openalex-snapshot
The Nuclear Receptor ERRα Is Required for the Bioenergetic and Functional Adaptation to Cardiac Pressure Overload
inferred← citeshttps://doi.org/10.1016/j.cmet.2007.08.004openalex-snapshot
The Transcriptional Corepressor RIP140 Regulates Oxidative Metabolism in Skeletal Muscle
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