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Single-cell transcription analysis of Plasmodium vivax blood-stage parasites identifies stage- and species-specific profiles of expression

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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A superfamily of variant genes encoded in the subtelomeric region of Plasmodium vivax
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Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites
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StringTie enables improved reconstruction of a transcriptome from RNA-seq reads
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Massively parallel digital transcriptional profiling of single cells
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A general and flexible method for signal extraction from single-cell RNA-seq data
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Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes
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Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross
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Characterization of P. vivax blood stage transcriptomes from field isolates reveals similarities among infections and complex gene isoforms
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New insights into the Plasmodium vivax transcriptome using RNA-Seq
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Chloroquine-ResistantPlasmodium vivaxfrom Indonesia
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The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites
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Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture
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Statistical significance for genomewide studies
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Role of Plasmodium vivax Duffy-binding protein 1 in invasion of Duffy-null Africans
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Transcriptome profiling of Plasmodium vivax in Saimiri monkeys identifies potential ligands for invasion
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A family of erythrocyte binding proteins of malaria parasites.
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New insights into the blood‐stage transcriptome of Plasmodium falciparum using RNA‐Seq
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PbGEST mediates malaria transmission to both mosquito and vertebrate host
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Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
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PLASMODIUM VIVAX CHESSON STRAIN
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Discovery of Gene Function by Expression Profiling of the Malaria Parasite Life Cycle
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The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle
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Plasmodium falciparumSTEVOR Proteins Are Highly Expressed in Patient Isolates and Located in the Surface Membranes of Infected Red Blood Cells and the Apical Tips of Merozoites
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Assessing the Genetic Diversity of the Aldolase Genes of Plasmodium falciparum and Plasmodium vivax and Its Potential Effect on Performance of Aldolase-Detecting Rapid Diagnostic Tests
inferredcites →https://doi.org/10.1128/mbio.00625-18openalex-snapshot
Bone Marrow Is a Major Parasite Reservoir in Plasmodium vivax Infection
inferredcites →https://doi.org/10.1146/annurev-micro-090817-062712openalex-snapshot
Regulation of Sexual Commitment and Gametocytogenesis in Malaria Parasites
inferredcites →https://doi.org/10.1182/blood-2014-08-596015openalex-snapshot
Plasmodium vivax: restricted tropism and rapid remodeling of CD71-positive reticulocytes
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Plasmodium vivax aldolase-specific monoclonal antibodies and its application in clinical diagnosis of malaria infections in China
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Concentration and purification by magnetic separation of the erythrocytic stages of all human Plasmodium species
inferredcites →https://doi.org/10.1186/1475-2875-9-129openalex-snapshot
Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests
inferredcites →https://doi.org/10.1186/s12864-015-2320-8openalex-snapshot
Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1
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Comparative transcriptomics of female and male gametocytes in Plasmodium berghei and the evolution of sex in alveolates
inferredcites →https://doi.org/10.1186/s12915-014-0086-0openalex-snapshot
A comprehensive evaluation of rodent malaria parasite genomes and gene expression
inferredcites →https://doi.org/10.1186/s12936-015-0612-8openalex-snapshot
Plasmodium knowlesi gene expression differs in ex vivo compared to in vitro blood-stage cultures
inferredcites →https://doi.org/10.1186/s12936-018-2584-yopenalex-snapshot
A multiplex assay for the sensitive detection and quantification of male and female Plasmodium falciparum gametocytes
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TheCaenorhabditis eleganshistone hairpin-binding protein is required for core histone gene expression and is essential for embryonic and postembryonic cell division
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Early evolution of histone mRNA 3′ end processing
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A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor
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Probing Plasmodium falciparum sexual commitment at the single-cell level
inferredcites →https://doi.org/10.12688/wellcomeopenres.9876.1openalex-snapshot
A new Plasmodium vivax reference sequence with improved assembly of the subtelomeres reveals an abundance of pir genes
inferredcites →https://doi.org/10.1371/journal.pntd.0000653openalex-snapshot
A Systems-Based Analysis of Plasmodium vivax Lifecycle Transcription from Human to Mosquito
inferredcites →https://doi.org/10.1371/journal.pntd.0001811openalex-snapshot
Whole Genome Sequencing of Field Isolates Provides Robust Characterization of Genetic Diversity in Plasmodium vivax
inferredcites →https://doi.org/10.1371/journal.pntd.0002569openalex-snapshot
De Novo Assembly of a Field Isolate Genome Reveals Novel Plasmodium vivax Erythrocyte Invasion Genes
inferredcites →https://doi.org/10.1371/journal.pntd.0005365openalex-snapshot
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile
inferredcites →https://doi.org/10.1371/journal.pntd.0006555openalex-snapshot
Genetic diversity in two Plasmodium vivax protein ligands for reticulocyte invasion
inferredcites →https://doi.org/10.1371/journal.ppat.1001165openalex-snapshot
Identification and Genome-Wide Prediction of DNA Binding Specificities for the ApiAP2 Family of Regulators from the Malaria Parasite
inferredcites →https://doi.org/10.1371/journal.ppat.1004558openalex-snapshot
Parasite Biomass-Related Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Vivax Malaria
inferredcites →https://doi.org/10.1371/journal.ppat.1006080openalex-snapshot
Plasmodium falciparum Nucleosomes Exhibit Reduced Stability and Lost Sequence Dependent Nucleosome Positioning
inferredcites →https://doi.org/10.1385/1-59259-271-6:85openalex-snapshot
Nonhuman Primate Models: II. Infection of Saimiri and Aotus Monkeys with Plasmodium vivax
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The Susceptibility of the Indonesian I/CDC Strain of Plasmodium vivax to Chloroquine
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Review : Reticulocyte maturation: mitoptosis and exosome release
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Global Epidemiology of Plasmodium vivax
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The Infection of Reticulocytes by Plasmodium Vivax
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Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Plasmodium vivax gametocytes and transmission
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Single-cell genome sequencing of protozoan parasites
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There and back again: malaria parasite single-cell transcriptomics comes full circle
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Single-cell views of the Plasmodium life cycle
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Dynamic Chromatin Structure and Epigenetics Control the Fate of Malaria Parasites
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Single-cell profiling reveals immunoregulation of artemisinin on CD8+GZMB+ T cells via JAK2-STAT3 in malaria-infected mice
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Application of single-cell transcriptomics to kinetoplastid research
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A single-cell atlas of Plasmodium falciparum transmission through the mosquito
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Stochastic expression of invasion genes in Plasmodium falciparum schizonts
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Humanized mice for investigating sustained Plasmodium vivax blood-stage infections and transmission
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Single-cell analyses of polyclonal Plasmodium vivax infections and their consequences on parasite transmission
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Identification of cross-stage, cross-species malaria CD8+ T cell antigens
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Single-cell RNA sequencing reveals developmental heterogeneity among Plasmodium berghei sporozoites
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A suitable RNA preparation methodology for whole transcriptome shotgun sequencing harvested from Plasmodium vivax-infected patients
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Novel single-cell preservation and RNA sequencing technology unlocks field studies for Plasmodium natural infections
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Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development
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Robustness and resilience of computational deconvolution methods for bulk RNA sequencing data
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Flowcytometric and ImageStream RNA-FISH Gene Expression, Quantification and Phenotypic Characterization of Blood Stages and Sporozoites From Human Malaria Species
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Low-volume Plasmodium blood sample processing protocols for untargeted transcriptomics optimized using Plasmodium knowlesi
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Efficient transcriptome profiling across the malaria parasite erythrocytic cycle by flow sorting
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Humanized mice for sustained Plasmodium vivax blood-stage infection and transmission
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Machine learning approaches for classification of Plasmodium falciparum life cycle stages using single-cell transcriptomes
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Comparative transcriptomics reveal differential gene expression in Plasmodium vivax geographical isolates and implications on erythrocyte invasion mechanisms
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The dynamic transcriptome of Plasmodium malariae in the mosquito
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Plasmodium vivax transcriptomics: What is new?
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Genome annotation with long RNA reads reveals new patterns of gene expression and improves single-cell analyses in an ant brain
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Analysis of pir gene expression across the Plasmodium life cycle
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Systems biology of malaria explored with nonhuman primates
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Comparative single-cell transcriptional atlases of Babesia species reveal conserved and species-specific expression profiles
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Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures
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Malian children infected with Plasmodium ovale and Plasmodium falciparum display very similar gene expression profiles
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Long read single cell RNA sequencing reveals the isoform diversity of Plasmodium vivax transcripts
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Comparative transcriptomics reveal differential gene expression among Plasmodium vivax geographical isolates and implications on erythrocyte invasion mechanisms
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Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages
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From Genes to Transcripts, a Tightly Regulated Journey in Plasmodium
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Band 3–mediated Plasmodium vivax invasion is associated with transcriptional variation in PvTRAg genes
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Differential Trafficking and Expression of PIR Proteins in Acute and Chronic Plasmodium Infections
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Paving the Way: Contributions of Big Data to Apicomplexan and Kinetoplastid Research
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Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets
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Plasmodium vivax spleen-dependent protein 1 and its role in extracellular vesicles-mediated intrasplenic infections
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Additional file 1 of Genome annotation with long RNA reads reveals new patterns of gene expression and improves single-cell analyses in an ant brain
inferred← citeshttps://doi.org/10.6084/m9.figshare.17087803openalex-snapshot
Additional file 3 of Genome annotation with long RNA reads reveals new patterns of gene expression and improves single-cell analyses in an ant brain
inferred← citeshttps://doi.org/10.6084/m9.figshare.17087806openalex-snapshot
Additional file 4 of Genome annotation with long RNA reads reveals new patterns of gene expression and improves single-cell analyses in an ant brain
inferred← citeshttps://doi.org/10.6084/m9.figshare.17087812openalex-snapshot
Additional file 5 of Genome annotation with long RNA reads reveals new patterns of gene expression and improves single-cell analyses in an ant brain
inferred← citeshttps://doi.org/10.6084/m9.figshare.17087815openalex-snapshot
Additional file 6 of Genome annotation with long RNA reads reveals new patterns of gene expression and improves single-cell analyses in an ant brain
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A Plasmodium knowlesi A1-H.1 transcriptome time course focusing on the late asexual blood stages
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Stage-aware transcriptomics reveals selective haplotype persistence in short-term ex vivo cultured Plasmodium vivax
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Humanized mice as model for Plasmodium vivax infection
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