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High mutation rates limit evolutionary adaptation in Escherichia coli
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Escherichia coli mutator genes
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Use of the rpoB gene to determine the specificity of base substitution mutations on the Escherichia coli chromosome
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Inbreeding in artificial selection programmes
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The constraints of finite size in asexual populations and the rate of the ratchet
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Inbreeding in artificial selection programmes
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The effect of linkage on limits to artificial selection
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Deleterious mutations and the evolution of sexual reproduction
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The Lower Bound to the Evolution of Mutation Rates
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The effect of deleterious mutations on neutral molecular variation.
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Rates of Spontaneous Mutation
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The Consequences of Growth of a Mutator Strain of Escherichia coli as Measured by Loss of Function Among Multiple Gene Targets and Loss of Fitness
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Long-Term Experimental Evolution inEscherichia coli.IX. Characterization of Insertion Sequence-Mediated Mutations and Rearrangements
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The Effect of Deleterious Alleles on Adaptation in Asexual Populations
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THE MUTATIONAL LOAD WITH EPISTATIC GENE INTERACTIONS IN FITNESS
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THE AVERAGE NUMBER OF GENERATIONS UNTIL FIXATION OF A MUTANT GENE IN A FINITE POPULATION
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SELECTION FOR HIGH MUTATION RATES IN CHEMOSTATS
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THE EVOLUTIONARY ADVANTAGE OF RECOMBINATION
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The Mutational Meltdown in Asexual Populations
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The Balance Between Mutators and Nonmutators in Asexual Populations
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Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli
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Precise measurement of the fitness effects of spontaneous mutations by droplet digital PCR inBurkholderia cenocepacia
inferred← citeshttps://doi.org/10.1093/genetics/iyac028openalex-snapshot
The effect of weak clonal interference on average fitness trajectories in the presence of macroscopic epistasis
inferred← citeshttps://doi.org/10.1093/genetics/iyaf157openalex-snapshot
The role of environmental stress in promoting mutators through evolutionary rescue: quantitative predictions
inferred← citeshttps://doi.org/10.1093/icb/icac146openalex-snapshot
Time-Series Sequences for Evolutionary Inferences
inferred← citeshttps://doi.org/10.1093/ismeco/ycaf205openalex-snapshot
Reciprocal transplantation experiments reveal local adaptation of seaweed-associated bacteria
inferred← citeshttps://doi.org/10.1093/mnrasl/slz166openalex-snapshot
Stellar proton event-induced surface radiation dose as a constraint on the habitability of terrestrial exoplanets
inferred← citeshttps://doi.org/10.1093/molbev/msab341openalex-snapshot
Multiple Novel Traits without Immediate Benefits Originate in Bacteria Evolving on Single Antibiotics
inferred← citeshttps://doi.org/10.1093/molbev/msaf182openalex-snapshot
Antimutator and Mutational Spectrum Effects Can Combine to Reduce Evolutionary Potential in Escherichia coli ΔnudJ
inferred← citeshttps://doi.org/10.1093/nar/gkab1244openalex-snapshot
Development of a genome-targeting mutator for the adaptive evolution of microbial cells
inferred← citeshttps://doi.org/10.1093/nar/gky751openalex-snapshot
Directed evolution of Escherichia coli with lower-than-natural plasmid mutation rates
inferred← citeshttps://doi.org/10.1101/2023.01.16.524324openalex-snapshot
A field theoretic approach to non-equilibrium population genetics in the strong selection regime
inferred← citeshttps://doi.org/10.1101/2024.08.20.608874openalex-snapshot
Quantifying microbial fitness in high-throughput experiments
inferred← citeshttps://doi.org/10.1101/2024.12.15.628562openalex-snapshot
Could Quantum-Mediated Bacterial Signaling Explain Adaptive Mutation?
inferred← citeshttps://doi.org/10.1101/2025.01.28.635215openalex-snapshot
Evolutionary potential of the Escherichia coli antimutator Δ nudJ is reduced via altered mutational spectrum
inferred← citeshttps://doi.org/10.1101/2025.09.22.677663openalex-snapshot
Mutation bias is a key predictor of adaptation rate
inferred← citeshttps://doi.org/10.1111/1755-0998.13649openalex-snapshot
A road map for in vivo evolution experiments with blood‐borne parasitic microbes
inferred← citeshttps://doi.org/10.1111/eva.13062openalex-snapshot
Application of simultaneous selective pressures slows adaptation
inferred← citeshttps://doi.org/10.1111/eva.13155openalex-snapshot
Interspecific hybrids show a reduced adaptive potential under DNA damaging conditions
inferred← citeshttps://doi.org/10.1111/eva.70069openalex-snapshot
Navigating Host Immunity and Concurrent Ozone Stress: Strain‐Resolved Metagenomics Reveals Maintenance of Intraspecific Diversity and Genetic Variation in Xanthomonas on Pepper
inferred← citeshttps://doi.org/10.1111/jeb.13764openalex-snapshot
Genomic signatures of UV resistance evolution in Escherichia coli depend on the growth phase during exposure
inferred← citeshttps://doi.org/10.1126/science.adh3860openalex-snapshot
A rugged yet easily navigable fitness landscape
inferred← citeshttps://doi.org/10.1128/mbio.01822-19openalex-snapshot
Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection
inferred← citeshttps://doi.org/10.1128/mbio.03310-25openalex-snapshot
The unique role of nucS -mediated noncanonical mismatch repair in Mycobacterium tuberculosis resistance evolution
inferred← citeshttps://doi.org/10.1128/msphere.00704-19openalex-snapshot
High Genomic Diversity and Heterogenous Origins of Pathogenic and Antibiotic-Resistant Escherichia coli in Household Settings Represent a Challenge to Reducing Transmission in Low-Income Settings
inferred← citeshttps://doi.org/10.1128/spectrum.02528-22openalex-snapshot
Transcriptional Potential Determines the Adaptability of Escherichia coli Strains with Different Fitness Backgrounds
inferred← citeshttps://doi.org/10.1142/s1793962323500034openalex-snapshot
A multi-optimization-based genetic algorithm mapper design for three transmit uncoded space-time diversity systems
inferred← citeshttps://doi.org/10.11606/d.76.2019.tde-14102019-163039openalex-snapshot
Estudo de parâmetros microbianos em múltiplas sessões de terapia fotodinâmica antimicrobiana
inferred← citeshttps://doi.org/10.1371/journal.pbio.3000617openalex-snapshot
Low mutational load and high mutation rate variation in gut commensal bacteria
inferred← citeshttps://doi.org/10.1371/journal.pbio.3002049openalex-snapshot
Increased male investment in sperm competition results in reduced maintenance of gametes
inferred← citeshttps://doi.org/10.1371/journal.pbio.3002711openalex-snapshot
Collective peroxide detoxification determines microbial mutation rate plasticity in E. coli
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1007727openalex-snapshot
Gene expression noise can promote the fixation of beneficial mutations in fluctuating environments
inferred← citeshttps://doi.org/10.1371/journal.pgen.1009806openalex-snapshot
Empirical estimates of the mutation rate for an alphabaculovirus
inferred← citeshttps://doi.org/10.1371/journal.pgen.1010030openalex-snapshot
Viral protein instability enhances host-range evolvability
inferred← citeshttps://doi.org/10.1371/journal.pgen.1011627openalex-snapshot
Quantitative analysis of relationship between mutation rate and speed of adaptation under antibiotic exposure in Escherichia coli
inferred← citeshttps://doi.org/10.1534/g3.120.401124openalex-snapshot
Escherichia coli with a Tunable Point Mutation Rate for Evolution Experiments
inferred← citeshttps://doi.org/10.1534/genetics.119.302754openalex-snapshot
Selective Inbreeding: Genetic Crosses Drive Apparent Adaptive Mutation in the Cairns-Foster System of Escherichia coli
inferred← citeshttps://doi.org/10.18174/557306openalex-snapshot
On the role of ribosomal proteins in stress resistance and fitness of Listeria monocytogenes : a laboratory evolution approach
inferred← citeshttps://doi.org/10.20944/preprints201812.0205.v1openalex-snapshot
Dynamic Evolution Hypothesis of Organisms
inferred← citeshttps://doi.org/10.22215/etd/2020-14245openalex-snapshot
Identification of Hypermutator Enterohemorrhagic Escherishia coli (EHEC) Using a High Throughput Screening Method to Inform Food Safety Investigations
inferred← citeshttps://doi.org/10.29350/qjps.2022.27.1.1604openalex-snapshot
Design of a bacterial system using Escherichia coli to detect the mutagenic effect of some drugs
inferred← citeshttps://doi.org/10.3126/njz.v6is1.50523openalex-snapshot
Molecular phylogeny of swallowtail butterflies (Lepidoptera: Papilionidae) based on mitochondrial cytochrome c oxidase I (COI) gene from Bangladesh
inferred← citeshttps://doi.org/10.32873/unl.dc.manter25openalex-snapshot
The Evolutionary Dynamics of Infectious Diseases on an Unstable Planet: Insights from Modeling the Stockholm Paradigm
inferred← citeshttps://doi.org/10.33612/diss.864174360openalex-snapshot
Evolvability and organismal architecture
inferred← citeshttps://doi.org/10.33612/diss.925124601openalex-snapshot
Evolvability in the context of antibiotic resistance
inferred← citeshttps://doi.org/10.3389/fevo.2024.1335452openalex-snapshot
Unravelling the factors of evolutionary repeatability: insights and perspectives on predictability in evolutionary biology
inferred← citeshttps://doi.org/10.3389/fmicb.2019.01845openalex-snapshot
Inactivation of a Mismatch-Repair System Diversifies Genotypic Landscape of Escherichia coli During Adaptive Laboratory Evolution
inferred← citeshttps://doi.org/10.3389/fmicb.2022.914040openalex-snapshot
A Nuclei-Based Conceptual Model of (Eco)evolutionary Dynamics in Fungal Heterokaryons
inferred← citeshttps://doi.org/10.3389/fmicb.2022.990969openalex-snapshot
Global coordination of the mutation and growth rates across the genetic and nutritional variety in Escherichia coli
inferred← citeshttps://doi.org/10.3390/antibiotics13050452openalex-snapshot
Genetic Alternatives for Experimental Adaptation to Colistin in Three Pseudomonas aeruginosa Lineages
inferred← citeshttps://doi.org/10.3390/ijms24108717openalex-snapshot
Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks
inferred← citeshttps://doi.org/10.3390/microorganisms11020275openalex-snapshot
Accelerated Adaptive Laboratory Evolution by Automated Repeated Batch Processes in Parallelized Bioreactors
inferred← citeshttps://doi.org/10.3390/philosophies6020033openalex-snapshot
To What Inanimate Matter Are We Most Closely Related and Does the Origin of Life Harbor Meaning?
inferred← citeshttps://doi.org/10.61186/ijbc.16.3.63openalex-snapshot
The Positive Impact of Virulence Genes in Bacterial Pathogenicity and Colonization on the Large Bowel in Colorectal Cancer Patients
inferred← citeshttps://doi.org/10.64898/2026.01.06.697716openalex-snapshot
Spontaneous mutation rate in Saccharomyces cerevisiae is lower in nutritional and genotypic conditions reducing specific growth rate
inferred← citeshttps://doi.org/10.7150/thno.59535openalex-snapshot
The therapeutic potential of inorganic polyphosphate: A versatile physiological polymer to control coronavirus disease (COVID-19)
inferred← citeshttps://doi.org/10.7554/elife.102635openalex-snapshot
Quantifying microbial fitness in high-throughput experiments
inferred← citeshttps://doi.org/10.7554/elife.102635.1openalex-snapshot
Quantifying microbial fitness in high-throughput experiments
inferred← citeshttps://doi.org/10.7554/elife.102635.3openalex-snapshot
Quantifying microbial fitness in high-throughput experiments
inferred← citeshttps://doi.org/10.7554/elife.78618openalex-snapshot
Vaccination decreases the risk of influenza A virus reassortment but not genetic variation in pigs
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